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- ------------------------- UNITED STATES SECURITIES AND EXCHANGE COMMISSION ------------------------------
FORM 4 Washington, D.C. 20549 OMB Approval
- ------------------------- STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP ------------------------------
[ ] Check this box if no OMB Number: 3235-0287
longer subject to Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Expires: September 30, 1998
Section 16. Form 4 Section 17(a) of the Public Utility Holding Company Act of 1935 or Estimated average burden
or Form 5 obligations Section 30(f) of the Investment Company Act of 1940 hours per response.......0.5
may continue. See ------------------------------
Instruction 1(b).
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(Print or Type Responses)
<S> <C> <C> <C>
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1. Name and Address of Reporting Person* 2. Issuer Name and Ticker 4. Statement for 6. Relationship of Reporting Person(s)
or Trading Symbol Month/Year to Issuer
(Check all applicable)
Pero Ronald W. OXiGENE, Inc. (OXGN) 12/99 [x] Director [ ] 10% Owner
------------------------------------ [x] Officer (give [ ] Other
(Last) (First) (Middle) title below) (specify below)
Chief Scientific Officer
c/o OXiGENE, Inc. ---------------------------------------
One Copley Place, Suite 602
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(Street) 3. I.R.S. Identification 5. If Amendment, 7. Individual or Joint/Group Filing
Number of Reporting Date of (Check Applicable Line)
Person (Voluntary) Original [X] Form Filed by One Reporting Person
Boston, MA 02116 (Month/Year) [ ] Form Filed by More than One
------------------------------------ Reporting Person
(City) (State) (Zip)
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TABLE I -- NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
<S> <C> <C> <C> <C> <C> <C>
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1. Title of Security 2. Trans- 3. Transaction 4. Securities Acquired (A) 5. Amount of 6. Ownership 7. Nature of
(Instr. 3) action Code (Instr. or Disposed of (D) Securities Form: Indirect
Date 8) (Instr. 3, 4 and 5) Beneficially Direct (D) Beneficial
(Month/ Owned at End or Indirect Ownership
Day/ of Month (I) (Instr. 4)
Year) (Instr. 3 (Instr. 4)
and 4)
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Code V Amount (A) or (D) Price
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Common Stock 12/15/99 S 26000 D 17.51 D
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Common Stock 12/15/99 S 11000 D 17.38 D
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Common Stock 12/15/99 S 8500 D 17.63 D
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Common Stock 12/15/99 S 3500 D 17.88 D
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Common Stock 12/15/99 S 1000 D 17.76 D
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Common Stock 12/16/99 S 2000 D 17.64 D
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Common Stock 12/16/99 S 1000 D 17.71 D
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Common Stock 12/16/99 S 23000 D 19.52 D
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Common Stock 12/16/99 S 22500 D 17.39 D
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Common Stock 12/16/99 S 10000 D 19.27 D
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Common Stock 12/16/99 S 9000 D 17.52 D
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Common Stock 12/16/99 S 4000 D 17.77 D
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Common Stock 12/16/99 S 17500 D 17.89 D
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Common Stock 12/16/99 S 1000 D 19.64 D
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Common Stock 12/16/99 S 1000 D 19.77 D
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Common Stock 12/20/99 S 5000 D 15.89 D
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Common Stock 12/20/99 S 22358 D 15.76 D
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Common Stock 12/20/99 S 10000 D 17.39 D
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Common Stock 12/20/99 S 10000 D 17.51 D
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Common Stock 12/20/99 S 10000 D 17.64 D
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Common Stock 12/20/99 S 2000 D 16.01 D
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Common Stock 12/20/99 S 1000 D 16.70 D
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Common Stock 12/20/99 S 200 D 16.51 D
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Common Stock 12/20/99 S 30 D 15.77 485,233 D
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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
SEC 1474 (7-96) (Over)
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FORM 4 (continued)
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TABLE II -- DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
(E.G., PUTS, CALLS, WARRANTS, OPTIONS, CONVERTIBLE SECURITIES)
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C> <C>
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1. Title 2. Conver- 3. Trans- 4. Trans- 5. Number of 6. Date 7. Title 8. Price 9. Number 10. Owner- 11. Nature of
of sion or action action Derivative Exer- and of of ship Indirect
Deri- Exercise Date Code Securities cisable Amount Deri- Deri- Form Beneficial
vative Price of (Instr. Acquired (A) and Expi- of vative vative of Deri- Ownership
Secu- Deri- (Month/ 8) or Disposed ration Under- Secu- Secu- vative (Instr. 4)
rity vative Day/ of (D) Date lying rity rities Security:
(Instr. Security Year) (Instr. 3, (Month/ Securi- (Instr. Benefi- Direct
3) 4, and 5) Day/ ties 5) cially (D) or
Year) (Instr. Owned Indirect
3 and 4) at End (I)
of (Instr.
Month 4)
(Instr.
4)
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Code V (A) (D) Date Expir- Title Amount
Exerci- ation or
sable Date Number
of
Shares
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Explanation of Responses:
<PAGE>
Ronald W. Pero
** Intentional misstatements or omissions of
facts constitute Federal Criminal Violations.
See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). By: /s/ Ronald W. Pero 5/25/00
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Ronald W. Pero Date
Note: File three copies of this Form, one of
which must be manually signed. If space
provided is insufficient, see Instruction
6 for procedure.
Potential persons who are to respond to the collection of information contained in this form are not required to respond unless form
displays a currently valid OMB number.
Page 2
SEC 1474 (7-97)
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