GLYKO BIOMEDICAL LTD
NT 10-K, 1999-03-31
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             Washington, D. C. 20549


                                   FORM 12b-25


                           NOTIFICATION OF LATE FILING

                                                    SEC FILE NUMBER: 000-21994

                                                    CUSIP NUMBER: 379904105


(Check One):      [ X ] Form 10-KSB [   ] Form 20-F           [   ]  Form 11-K
                  [   ] Form 10-QSB [   ] Form N-SAR


                  For Period Ended:           December 31, 1998     
             
                 [ ]  Transition Report on Form 10-K 
                 [ ]  Transition Report on Form 20-F
                 [ ]  Transition Report on Form 11-K
                 [ ]  Transition Report on Form 10-Q
                 [ ]  Transition Report on Form N-SAR               
                 For the Transition Period Ended:                               

Read Instruction (on back page) Before Preparing Form.  Please Print or Type.
Nothing  in this  form  shall be  construed  to imply  that the  Commission  has
verified any information contained herein.

If the notification  relates to a portion of the filing checked above,  identify
the Item(s) to which the notification relates:




PART I - REGISTRANT INFORMATION

Full Name of Registrant GLYKO BIOMEDICAL, LTD.

Former Name if Applicable N/A                                                  

Address of Principal Executive Office (Street and Number) 371 Bel Marin Keys
Blvd. #210

City, State and Zip Code   Novato, California  94949                           


PART II - RULES 12b-25(b) AND (c)

If the subject  report could not be filed without  reasonable  effort or expense
and the  registrant  seeks relief  pursuant to Rule  12-b-25(b),  the  following
should be completed. (Check box if appropriate)

[X]  (a) The reasons described in reasonable detail in Part III of this form
         could not be eliminated without reasonable effort or expense;
[X]  (b) The subject annual report, semi-annual report, transition report on
         Form 10-KSB,  Form 20-F, 11-K, or Form N-SAR, or portion thereof,  will
         be  filed  on or  before  the  fifteenth  calendar  day  following  the
         prescribed  due date;  or the subject  quarterly  report of  transition
         report on Form  10-QSB,  or portion  thereof will be filed on or before
         the fifteenth calendar day following the prescribed due date; and
[ ]  (c) The  accountant's  statement  or other  exhibit  required by Rule
         12b-25(c) has been attached if applicable.



<PAGE>



PART III - NARRATIVE

   State below in reasonable detail the reasons why the Form 10-KSB, 11-K, 
10-QSB, N-SAR, or the transition report or portion thereof, could not be filed
within the prescribed time period.  (Attach Extra Sheets if Needed)

A company  affiliated with Glyko  Biomedical,  Ltd., of which Glyko  Biomedical,
Ltd. owns less than fifty percent (50%) of the  outstanding  capital stock,  was
unable to  complete  its audit in time to include  information  related to it in
Glyko Biomedical,  Ltd.'s 10-KSB. As this affiliate represents Glyko Biomedical,
Ltd.'s  principal  asset, the results of operations of the affiliate will have a
material impact on Glyko Biomedical,  Ltd.'s business,  financial  condition and
results of operations.


PART IV - OTHER INFORMATION

(1)      Name and telephone number of person to contact in regard to this 
          notification
         Raymond W. Anderson            (415)                 382-3500         
         (Name)                     (Area Code)      (Telephone Number)

(2)      Have all other periodic  reports  required under Section 13 or 15(d) of
         the  Securities  Exchange  Act of 1934 or Section 30 of the  Investment
         Company  Act of 1940  during  the  preceding  12  months  (or for  such
         shorter) period that the registrant was required to file such report(s)
         been filed? If answer is no, identify report(s).
                 [ X ] Yes  [  ] No

(3)      Is it anticipated that any significant  change in results of operations
         from  the  corresponding  period  for  the  last  fiscal  year  will be
         reflected  by the  earnings  statements  to be  included in the subject
         report or portion thereof?
                 [  ]  Yes [ X ]  No

         If  so,  attach  an  explanation  of  the  anticipated   change,   both
         narratively and quantitatively,  and, if appropriate, state the reasons
         why a reasonable estimate of the results cannot be made.



                             GLYKO BIOMEDICAL, LTD.
                  (Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned 
hereunto duly authorized.

Date:  March 30, 1999                    By:  /s/    John C. Klock, M.D.       
       --------------                    ---------------------------------------
                                             John C. Klock, M.D., President

INSTRUCTION: The form may be signed by an executive officer of the registrant or
by any other duly  authorized  representative.  The name and title of the person
signing  the form  shall  be typed or  printed  beneath  the  signature.  If the
statement is signed on behalf of the registrant by an authorized  representative
(other than an executive officer), evidence of the representative's authority to
sign on behalf of the registrant shall be filed with the form.







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