FARALLON CAPITAL MANAGEMENT LLC
SC 13D, 2000-01-11
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                                   PURSUANT TO
                          RULE 101(d) OF REGULATION S-T

                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                  SCHEDULE 13D
                                 (Rule 13d-101)

             INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
            TO RULE 13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO
                                  RULE 13d-2(a)

                           (Amendment No. _________)1

                     Spiros Development Corporation II, Inc.
                                (Name of Issuer)

                Callable Common Stock, par value $.001 per share
   (Formerly Traded as Part of Spiros Development Corporation II, Inc. Units)
                         (Title of Class of Securities)

                                    848936100
                                 (CUSIP Number)

                                 Mark C. Wehrly
                       Farallon Capital Management, L.L.C.
                         One Maritime Plaza, Suite 1325
                         San Francisco, California 94111
                                 (415) 421-2132
                  (Name, Address and Telephone Number of Person
                Authorized to Receive Notices and Communications)

                                January 1, 2000
             (Date of Event which Requires Filing of this Statement)

     If the filing  person has  previously  filed a statement on Schedule 13G to
report the  acquisition  that is the subject of this Schedule 13D, and is filing
this  schedule  because  of Rule  13d-1(e),  13d-1(f)  or  13d-1(g),  check  the
following box [ ].

          Note.  Schedules filed in paper format shall include a signed original
     and five copies of the schedule,  including all exhibits. See Rule 13d-7(b)
     for other parties to whom copies are to be sent.

                         (Continued on following pages)
                               Page 1 of 39 Pages
                         Exhibit Index Found on Page 38



- -----------------------
     1 The  remainder  of this cover  page  shall be filled out for a  reporting
person's  initial  filing on this  form with  respect  to the  subject  class of
securities,  and for any subsequent amendment containing information which would
alter disclosures provided in a prior cover page.

     The  information  required on the remainder of this cover page shall not be
deemed to be "filed"  for the purpose of Section 18 of the  Securities  Exchange
Act of 1934 or otherwise  subject to the  liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================
- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Farallon Capital Partners, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however, is a beneficial
            owner only of the securities reported by it on this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         WC, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         California
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           259,200 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      259,200 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE  AMOUNT  BENEFICIALLY  OWNED BY EACH REPORTING PERSON
         259,200
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         4.1% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 2 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Farallon Capital Institutional Partners, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however, is a beneficial
            owner only of the securities reported by it on this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         WC
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         California
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           249,100 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      249,100 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE  AMOUNT  BENEFICIALLY  OWNED BY EACH REPORTING PERSON
         249,100
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         3.9% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 3 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Farallon Capital Institutional Partners II, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however, is a beneficial
            owner only of the securities reported by it on this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         WC
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         California
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           127,200 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      127,200 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE  AMOUNT  BENEFICIALLY  OWNED BY EACH REPORTING PERSON
         127,200
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         2.0% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 4 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Farallon Capital Institutional Partners III, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however, is a beneficial
            owner only of the securities reported by it on this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         WC
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         Delaware
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           214,800 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      214,800 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE  AMOUNT  BENEFICIALLY  OWNED BY EACH REPORTING PERSON
         214,800
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         3.4% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 5 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Tinicum Partners, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however, is a beneficial
            owner only of the securities reported by it on this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         WC, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         New York
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           21,900 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      21,900 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE  AMOUNT  BENEFICIALLY  OWNED BY EACH REPORTING  PERSON
         21,900
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         0.3% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 6 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Farallon Capital Management, L.L.C.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         Delaware
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           502,200 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      502,200 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE  AMOUNT  BENEFICIALLY  OWNED BY EACH REPORTING PERSON
         502,200
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         7.9% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IA, OO
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 7 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Farallon Partners, L.L.C.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         Delaware
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           872,200 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      872,200 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE  AMOUNT  BENEFICIALLY  OWNED BY EACH REPORTING PERSON
         872,200
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         13.8% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         OO
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 8 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Enrique H. Boilini
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         Argentina
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 9 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         David I. Cohen
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         South Africa
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 10 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Joseph F. Downes
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 11 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         William F. Duhamel
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 12 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Fleur E. Fairman
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           872,200 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      872,200 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE  AMOUNT  BENEFICIALLY  OWNED BY EACH REPORTING PERSON
         872,200
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         13.8% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 13 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Jason M. Fish
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 14 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Andrew B. Fremder
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 15 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Richard B. Fried
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 16 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         William F. Mellin
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 17 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Stephen L. Millham
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 18 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Meridee A. Moore
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 19 of 39 Pages
<PAGE>


                                       13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Thomas F. Steyer
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY
- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


                              Page 20 of 39 Pages
<PAGE>

                                      13D
===============================
CUSIP No. 848936100
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
         Mark C. Wehrly
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [   ]
                                                                 (b) [ X ]**
         ** The reporting  persons  making this filing hold an aggregate  of
            1,374,400 Shares, which is 21.7% of the class of securities.
            The reporting person on this cover page, however,  may be
            deemed a beneficial owner only of the securities reported by it on
            this cover page.
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*
         AF, OO
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                     [   ]
- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION
         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY           1,374,400 [See 11 below and the Preliminary Note.]
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER
                      1,374,400 [See 11 below and the Preliminary Note.]
- ----------------------=========================================================
   11    AGGREGATE AMOUNT  BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,374,400
         [Reflects the separation of the Spiros Development Corporation II, Inc.
         Units into underlying  Spiros  Development  Corporation II, Inc. Shares
         and Dura Pharmaceuticals, Inc. Warrants as described in the Preliminary
         Note herein. The Reporting Person's beneficial  ownership in the Spiros
         Development  Corporation  II, Inc.  Shares  underlying the Units is the
         same as it was prior to  separation.  See the Schedule 13D filed by the
         Reporting Person with respect to the Spiros Development Corporation II,
         Inc. Units. See also the Preliminary Note.]
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*
                                                                     [   ]
- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
         21.7% [Reflects the separation of the Spiros Development Corporation
         II, Inc. Units into underlying Spiros Development Corporation II,
         Inc. Shares and Dura Pharmaceuticals, Inc. Warrants as described in
         the Preliminary Note herein.  The Reporting Person's beneficial
         ownership in the Spiros Development Corporation II, Inc. Shares
         underlying the Units is the same as it was prior to separation.  See
         the Schedule 13D filed by the Reporting Person with respect to the
         Spiros Development Corporation II, Inc. Units.  See also the
         Preliminary Note.]
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*
         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 21 of 39 Pages
<PAGE>


Preliminary Note.

     On January 1, 2000 (the "Separation Date"), the Units of Spiros Development
Corporation  II,  Inc.  (the  "Units"),  each  composed of one share of callable
common stock, par value $.001 per share, of Spiros  Development  Corporation II,
Inc.  (the  "Shares")  and one  warrant to  purchase  1/4 of one share of common
stock,  par  value  $.001  per  share,  of  Dura   Pharmaceuticals,   Inc.  (the
"Warrants"),  separated. As a result of the separation, the component Shares and
Warrants began trading  independently  and the Units have ceased to exist.  This
Schedule  13D is being filed to report  beneficial  ownership  of the Shares (as
opposed  to the  Units) as a result of the  separation  of the  Shares  from the
Units.  There have been no  transactions  in the Shares by any of the  Reporting
Persons (as defined below) since the Separation Date.

     Prior to the Separation Date, the Reporting Persons had reported beneficial
ownership  of the Units on a  Schedule  13D which was most  recently  amended on
November 12, 1999.

Item 1. Security And Issuer.

     This statement  relates to shares of Callable Common Stock, par value $.001
per share  (the  "Shares")  of Spiros  Development  Corporation  II,  Inc.  (the
"Company").  The Company's principal offices are located at 7475 Lusk Boulevard,
San Diego, California, 92121.

Item 2. Identity And Background.

     (a) This statement is filed by the entities and persons  listed below,  all
of whom together are referred to herein as the "Reporting Persons."

      The Partnerships

            (i)   Farallon  Capital   Partners,   L.P.,  a  California   limited
                  partnership ("FCP"), with respect to the Shares held by it;

            (ii)  Farallon Capital  Institutional  Partners,  L.P., a California
                  limited partnership ("FCIP"),  with respect to the Shares held
                  by it;


                              Page 22 of 39 Pages
<PAGE>

            (iii) Farallon Capital Institutional Partners II, L.P., a California
                  limited  partnership  ("FCIP II"),  with respect to the Shares
                  held by it;

            (iv)  Farallon Capital Institutional  Partners III, L.P., a Delaware
                  limited  partnership  ("FCIP III"), with respect to the Shares
                  held by it; and

             (v)  Tinicum  Partners,   L.P.,  a  New  York  limited  partnership
                  ("Tinicum"), with respect to the Shares held by it.

     FCP, FCIP, FCIP II, FCIP III and Tinicum are together referred to herein as
the "Partnerships."

      The Management Company

            (vi)  Farallon  Capital  Management,   L.L.C.,  a  Delaware  limited
                  liability company (the "Management Company"),  with respect to
                  the Shares held by certain  accounts managed by the Management
                  Company (the "Managed Accounts").2

      The General Partner Of The Partnerships

            (vii) Farallon  Partners,   L.L.C.,  a  Delaware  limited  liability
                  company   which  is  the  general   partner  of  each  of  the
                  Partnerships  (the  "General  Partner"),  with  respect to the
                  Shares held by each of the Partnerships.

      The Managing Members Of The General Partner And The Management Company

            (viii) The  following  twelve  persons who are managing  members of
                   both the General  Partner and the Management  Company,  with
                   respect  to the  Shares  held  by the  Partnerships  and the
                   Managed Accounts:  Enrique H. Boilini ("Boilini"),  David I.
                   Cohen  ("Cohen"),  Joseph F. Downes  ("Downes"),  William F.
                   Duhamel  ("Duhamel"),  Jason M.  Fish  ("Fish"),  Andrew  B.
                   Fremder ("Fremder"),  Richard B. Fried ("Fried"), William F.
                   Mellin ("Mellin"),  Stephen L. Millham ("Millham"),  Meridee
                   A. Moore ("Moore"),  Thomas F. Steyer ("Steyer") and Mark C.
                   Wehrly ("Wehrly"); and

            (ix)  the thirteenth  managing member of the General Partner,  Fleur
                  E. Fairman ("Fairman"), with respect to the Shares held by the
                  Partnerships.


- -----------------------
     2 Of the Shares reported by the Management Company on behalf of the Managed
Accounts,  53,100  Shares  (equal  to  approximately  0.8% of the  total  Shares
currently  outstanding) are held by The Absolute Return Fund of The Common Fund,
a  non-profit  corporation  whose  principal  address  is 450  Post  Road  East,
Westport, Connecticut 06881.

                              Page 23 of 39 Pages
<PAGE>

     Boilini,  Cohen, Downes,  Duhamel,  Fairman, Fish, Fremder,  Fried, Mellin,
Millham,  Moore,  Steyer  and  Wehrly  are  together  referred  to herein as the
"Individual Reporting Persons."

     (b) The address of the principal  business and principal  office of (i) the
Partnerships,  the General  Partner and the  Management  Company is One Maritime
Plaza,  Suite  1325,  San  Francisco,  California  94111  and  (ii)  each of the
Individual Reporting Persons is set forth in Annex 1 hereto.

     (c) The principal business of each of the Partnerships is that of a private
investment  fund  engaging in the purchase and sale of  investments  for its own
account.  The principal business of the General Partner is to act as the general
partner of the Partnerships. The principal business of the Management Company is
that of a registered  investment adviser.  The principal business of each of the
Individual Reporting Persons is set forth in Annex 1 hereto.

     (d) None of the Partnerships,  the Management Company,  the General Partner
or any of the Individual Reporting Persons has, during the last five years, been
convicted in a criminal  proceeding  (excluding  traffic  violations  or similar
misdemeanors).

     (e) None of the Partnerships,  the Management Company,  the General Partner
or any of the Individual Reporting Persons has, during the last five years, been
party to a civil  proceeding of a judicial or  administrative  body of competent
jurisdiction and as a result of such proceeding was or is subject to a judgment,
decree  or final  order  enjoining  future  violations  of,  or  prohibiting  or
mandating activities subject to, federal or state securities laws or finding any
violation with respect to such laws.

     (f) The  citizenship of each of the  Partnerships,  the General Partner and
the  Management  Company is set forth above.  Each of the  Individual  Reporting
Persons is a United  States  citizen other than (i) Enrique H. Boilini who is an
Argentinean citizen and (ii) David I. Cohen who is a South African citizen.


                              Page 24 of 39 Pages
<PAGE>

     The other  information  required  by Item 2 relating  to the  identity  and
background of the Reporting Persons is set forth in Annex 1 hereto.

Item 3. Source And Amount Of Funds And Other Consideration.

     As stated in the  Preliminary  Note,  this  Schedule  13D is being filed to
reflect the separation of the Shares from the Units on the Separation  Date. The
net  investment  costs  (including  commissions)  for all Units  acquired by the
Reporting  Persons  through the filing of the last amendment to the Schedule 13D
filed by the  Reporting  Persons with respect to the Units were reported in that
Schedule 13D. As stated therein,  for purposes of such filings,  100% of the net
Unit price for each Unit was  attributed to the  underlying  Share.  For further
information  regarding the net investment costs (including  commissions) of such
Units (and corresponding Shares), see the Schedule 13D, as amended, filed by the
Reporting Persons with respect to the Units.

     The net investment cost for the Shares underlying the Units purchased since
the filing of the last amendment to the Schedule 13D through the Separation Date
is as follows:

      Entity        Shares Acquired3    Approximate Net Investment Cost4
      FCP              11,700                $59,905.50
      FCIP             11,000                $56,318.00
      FCIP II           1,900                 $9,728.00
      FCIP III          2,600                $13,306.00
      Tinicum             700                 $3,587.50
      Managed
        Accounts       19,600               $100,355.00

     The consideration  for such acquisitions was obtained as follows:  (i) with
respect to FCIP, FCIP II and FCIP III, from working  capital;  (ii) with respect
to FCP and Tinicum, from working


- -----------------------
     3 All  the  Shares  were  acquired  as  part of the  Units  at the  time of
purchase.

     4 As the Shares  traded as part of the Units at the time of  purchase,  the
reported  cost is a per Unit cost.  For purposes of this  Schedule  13D, the net
investment cost attributes all the Unit cost to the related Share.



                              Page 25 of 39 Pages
<PAGE>

capital,  and/or from borrowings  pursuant to margin accounts  maintained in the
ordinary  course of business by FCP and  Tinicum at  Goldman,  Sachs & Co.;  and
(iii) with  respect to the Managed  Accounts,  from the working  capital of each
Managed Account and/or from borrowings pursuant to margin accounts maintained in
the  ordinary  course of business  by some of the  Managed  Accounts at Goldman,
Sachs  & Co.  FCP,  Tinicum  and  some  of the  Managed  Accounts  hold  certain
securities in their respective margin accounts at Goldman,  Sachs & Co., and the
accounts  may from time to time  have  debit  balances.  It is not  possible  to
determine the amount of borrowings, if any, used to acquire the Shares.

Item 4. Purpose Of The Transaction.

     The purpose of the  acquisition  of the Shares is for  investment,  and the
acquisitions of the Shares by each of the  Partnerships and the Managed Accounts
were made in the  ordinary  course of business and were not made for the purpose
of acquiring control of the Company.

     Although no Reporting  Person has any specific  plan or proposal to acquire
or dispose of Shares,  consistent  with its investment  purpose,  each Reporting
Person  at any time  and from  time to time may  acquire  additional  Shares  or
dispose of any or all of its Shares depending upon an ongoing  evaluation of the
investment  in  the  Shares,  prevailing  market  conditions,  other  investment
opportunities,  liquidity  requirements  of the  Reporting  Person  and/or other
investment  considerations.   No  Reporting  Person  has  made  a  determination
regarding a maximum or minimum  number of Shares  which it may hold at any point
in time.

     Also,  consistent with their investment  intent,  the Reporting Persons may
engage in communications  with one or more  shareholders of the Company,  one or
more  officers  of the  Company  and/or  one or more  members  of the  board  of
directors of the Company regarding the Company, including but not limited to its
operations.


                              Page 26 of 39 Pages
<PAGE>

     Except to the extent the foregoing  may be deemed a plan or proposal,  none
of the  Reporting  Persons has any plans or proposals  which relate to, or could
result in,  any of the  matters  referred  to in  paragraphs  (a)  through  (j),
inclusive,  of the instructions to Item 4 of Schedule 13D. The Reporting Persons
may,  at any time and from time to time,  review or  reconsider  their  position
and/or change their purpose  and/or  formulate  plans or proposals  with respect
thereto.

Item 5. Interest In Securities Of The Issuer.

     (a) The Partnerships

          (a),(b)   The  information set forth in Rows 7 through 13 of the cover
                    page hereto for each  Partnership is incorporated  herein by
                    reference for each such  Partnership.  The percentage amount
                    set forth in Row 13 of each  cover page  filed  herewith  as
                    well as  Footnote  Two hereto is  calculated  based upon the
                    6,325,000  Shares  outstanding  as of  November  1,  1999 as
                    reported by the Company in its Quarterly Report on Form 10-Q
                    for the  period  ended  September  30,  1999  filed with the
                    Securities and Exchange Commission on November 15, 1999.

          (c)  The trade dates, number of Shares purchased or sold and the price
               per Share (including  commissions) for all purchases and sales of
               the Shares by the Partnerships  since the filing of Amendment No.
               8 to Schedule 13D filed by the Reporting  Persons with respect to
               the Units on  November  12, 1999 are set forth on  Schedules  A-E
               hereto  and are  incorporated  herein by  reference.  All of such
               transactions were open-market transactions.

          (d)  The  General  Partner  has the power to direct the affairs of the
               Partnerships,  including the  disposition  of the proceeds of the
               sale of the Shares. The Individual Reporting Persons are managing
               members of the General Partner.

          (e)  Not applicable.

     (b)  The Management Company


          (a),(b)   The  information set forth in Rows 7 through 13 of the cover
                    page  hereto  for the  Management  Company  is  incorporated
                    herein by reference.

          (c)  The trade dates, number of Shares purchased or sold and the price
               per Share (including  commissions) for all purchases and sales of
               the Shares by


                              Page 27 of 39 Pages
<PAGE>

               the Partnerships  since the filing of Amendment No. 8 to Schedule
               13D filed by the  Reporting  Persons with respect to the Units on
               November  12,  1999 are set forth on  Schedule  F hereto  and are
               incorporated  herein by reference.  All of such transactions were
               open-market transactions.

          (d)  The Management Company,  as an investment adviser,  has the power
               to direct  the  disposition  of the  proceeds  of the sale of the
               Shares held by the Managed  Accounts.  The  Individual  Reporting
               Persons other than Fairman are managing members of the Management
               Company.

          (e)  Not applicable.

     (c) The General Partner

          (a),(b)   The  information set forth in Rows 7 through 13 of the cover
                    page hereto for the General Partner is  incorporated  herein
                    by reference.

          (c)  None.

          (d)  The  General  Partner  has the power to direct the affairs of the
               Partnerships,  including the  disposition  of the proceeds of the
               sale of the Shares. The Individual Reporting Persons are managing
               members of the General Partner.

          (e)  Not applicable.

     (d) The Individual Reporting Persons

          (a),(b)   The  information set forth in Rows 7 through 13 of the cover
                    page  hereto  for  each  Individual   Reporting   Person  is
                    incorporated  herein by reference  for each such  Individual
                    Reporting Person.

          (c)  None.

          (d)  The  General  Partner  has the power to direct the affairs of the
               Partnerships,  including the  disposition  of the proceeds of the
               sale of the Shares.  The  Management  Company,  as an  investment
               adviser,  has the power to direct the disposition of the proceeds
               of the  sale of the  Shares  held by the  Managed  Accounts.  The
               Individual  Reporting Persons are managing members of the General
               Partner.  The Individual Reporting Persons other than Fairman are
               managing members of the Management Company.

          (e)  Not applicable.


      The Shares reported hereby for the  Partnerships are owned directly by the
Partnerships  and those  reported  by the  Management  Company  on behalf of the
Managed  Accounts  are owned  directly


                              Page 28 of 39 Pages
<PAGE>

by the  Managed  Accounts.  The  General  Partner,  as  general  partner  to the
Partnerships,  may be deemed to be the beneficial owner of all such Shares owned
by the  Partnerships.  The  Management  Company,  as  investment  adviser to the
Managed  Accounts,  may be deemed to be the beneficial  owner of all such Shares
owned by the Managed Accounts.  The eleven Individual  Reporting Persons who are
managing members of both the General Partner and the Management Company may each
be deemed to be the beneficial owner of all such Shares held by the Partnerships
and the  Managed  Accounts.  Fairman,  as a managing  member of only the General
Partner, may be deemed to be the beneficial owner of all such Shares held by the
Partnerships.  Each of the  Management  Company,  the  General  Partner  and the
Individual  Reporting  Persons hereby disclaims any beneficial  ownership of any
such Shares.

Item 6. Contracts, Arrangements, Understandings Or
        Relationships With Respect To Securities Of The Issuer.

     Except  as  described   above,   there  are  no  contracts,   arrangements,
understandings or relationships (legal or otherwise) among the Reporting Persons
or between such persons and any other person with respect to any  securities  of
the Company,  including but not limited to transfer or voting of any  securities
of the Company, finder's fees, joint ventures, loan or option arrangements, puts
or calls, guarantees of profits,  divisions of profits or loss, or the giving or
withholding of proxies.

Item 7. Materials To Be Filed As Exhibits.

     There is filed  herewith as Exhibit 1 a written  agreement  relating to the
filing of joint acquisition statements as required by Rule 13d-1(f)(1) under the
Securities Exchange Act of 1934, as amended.


                              Page 29 of 39 Pages
<PAGE>


                                   SIGNATURES

     After reasonable  inquiry and to the best of our knowledge and belief,  the
undersigned  certify that the  information  set forth in this statement is true,
complete and correct.

Dated: January 11, 2000

                    /s/ Thomas F. Steyer
                    ----------------------------------------
                    FARALLON PARTNERS, L.L.C.,
                    on its own behalf and as General Partner of
                    FARALLON CAPITAL PARTNERS, L.P.,
                    FARALLON CAPITAL INSTITUTIONAL PARTNERS, L.P.,
                    FARALLON CAPITAL INSTITUTIONAL PARTNERS II, L.P.,
                    FARALLON CAPITAL INSTITUTIONAL PARTNERS III, L.P.,
                    And TINICUM PARTNERS, L.P.,
                    By Thomas F. Steyer,
                    Senior Managing Member

                    /s/ Thomas F. Steyer
                    ----------------------------------------
                    FARALLON CAPITAL MANAGEMENT, L.L.C.,
                    By Thomas F. Steyer,
                    Senior Managing Member

                    /s/ Thomas F. Steyer
                    ----------------------------------------
                    Thomas F. Steyer, individually and as attorney-in-fact
                    for each of Enrique H. Boilini,  David I. Cohen,
                    Joseph F. Downes, William F. Duhamel, Fleur E. Fairman,
                    Jason M. Fish, Andrew B. Fremder, Richard B. Fried,
                    William F. Mellin, Stephen L. Millham, Meridee A. Moore
                    and Mark C. Wehrly.

     The Powers of Attorney,  each executed by Boilini,  Cohen, Downes, Fairman,
Fish,  Fremder,  Mellin,  Millham and Moore authorizing  Steyer to sign and file
this Schedule 13D on each person's behalf, which were filed with Amendment No. 1
to the  Schedule  13D filed  with the  Securities  and  Exchange  Commission  on
September 26, 1997, by such  Reporting  Persons with respect to the Common Stock
of Sphere Drake Holdings  Limited,  are hereby  incorporated  by reference.  The
Powers of Attorney executed by Duhamel and Fried authorizing  Steyer to sign and
file this Schedule 13D on each person's behalf,  which were filed with Amendment
No. 1 to the Schedule 13G filed with the Securities  and Exchange  Commission on
January 13, 1999, by such Reporting Persons with respect to the Callable Class A
Common  Shares  of  CliniChem  Development  Inc.,  are  hereby  incorporated  by
reference.  The Power of Attorney executed by Mark C. Wehrly  authorizing Steyer
to sign and file this Schedule 13D on his behalf, which was filed with Amendment
No. 2 to the Schedule 13D filed with the Securities  and Exchange  Commission on
January 10, 2000, by such Reporting  Person with respect to the Common Shares of
Axogen Limited, is hereby incorporated by reference.


                              Page 30 of 39 Pages
<PAGE>


                                                                         ANNEX 1



     Set forth  below with  respect to the  Management  Company  and the General
Partner is the  following  information:  (a) name;  (b) address;  (c)  principal
business;  (d) state of  organization;  and (e) controlling  persons.  Set forth
below with respect to each  managing  member of the  Management  Company and the
General Partner is the following:  (a) name; (b) business address; (c) principal
occupation; and (d) citizenship.

1.    The Management Company

      (a)   Farallon Capital Management, L.L.C.
      (b)   One Maritime Plaza, Suite 1325
            San Francisco, California  94111
      (c)   Serves as investment adviser to various managed accounts
      (d)   Delaware limited liability company
      (e)   Managing  Members:  Thomas  F.  Steyer,  Senior  Managing  Member;
            Enrique H. Boilini,  David I. Cohen, Joseph F. Downes,  William F.
            Duhamel,  Jason M. Fish,  Andrew B.  Fremder,  Richard  B.  Fried,
            William F. Mellin,  Stephen L. Millham,  Meridee A. Moore and Mark
            C. Wehrly, Managing Members.

2.    The General Partner

      (a)   Farallon Partners, L.L.C.
      (b)   c/o Farallon Capital Management, L.L.C.
            One Maritime Plaza, Suite 1325
            San Francisco, California  94111
      (c)   Serves as general partner to investment partnerships
      (d)   Delaware limited liability company
      (e)   Managing  Members:  Thomas  F.  Steyer,  Senior  Managing  Member;
            Enrique H. Boilini,  David I. Cohen, Joseph F. Downes,  William F.
            Duhamel,  Fleur E.  Fairman,  Jason M.  Fish,  Andrew B.  Fremder,
            Richard B. Fried, William F. Mellin,  Stephen L. Millham,  Meridee
            A. Moore and Mark C. Wehrly, Managing Members.

3.    The Individual Reporting Persons

      Except as stated  below,  each of the  Individual  Reporting  Persons is a
      United  States  citizen  whose  business  address is c/o Farallon  Capital
      Management,  L.L.C.,  One  Maritime  Plaza,  Suite  1325,  San  Francisco,
      California  94111.  Enrique H.  Boilini is an  Argentinean  citizen  whose
      business address is c/o Farallon Capital Management, L.L.C., 75 Holly Hill
      Lane,  Greenwich,  Connecticut  06830.  David I. Cohen is a South  African
      citizen. The principal occupation of Thomas F. Steyer is serving as senior
      managing  member of the Management  Company and the General  Partner.  The
      principal  occupation  of Fairman  is serving as a managing  member of the
      General  Partner.  The  principal  occupation  of  each  other  Individual
      Reporting  Person is serving as a managing  member of both the  Management
      Company and the General Partner.

                              Page 31 of 39 Pages
<PAGE>


                                   SCHEDULE A

                         FARALLON CAPITAL PARTNERS, L.P.


                                 NO. OF SHARES5
                                 PURCHASED (P)              PRICE
       TRADE DATE                 OR SOLD (S)             PER SHARE6

        12-15-99                   8,800 (P)               $5.13
        12-17-99                    600 (P)                $5.03
        12-17-99                   2,300 (P)               $5.13










- -----------------------
     5 All  the  Shares  were  acquired  as  part of the  Units  at the  time of
purchase.

     6 As the Shares  traded as part of the Units at the time of  purchase,  the
reported  cost is a per Unit cost.  For purposes of this  Schedule  13D, the net
investment cost attributes all the Unit cost to the related Share.


                              Page 32 of 39 Pages
<PAGE>


                                   SCHEDULE B

                  FARALLON CAPITAL INSTITUTIONAL PARTNERS, L.P.


                                 NO. OF SHARES7
                                 PURCHASED (P)              PRICE
       TRADE DATE                 OR SOLD (S)             PER SHARE8

        12-15-99                   8,100 (P)               $5.13
        12-17-99                    600 (P)                $5.03
        12-17-99                   2,300 (P)               $5.13












- -----------------------
     7 All  the  Shares  were  acquired  as  part of the  Units  at the  time of
purchase.

     8 As the Shares  traded as part of the Units at the time of  purchase,  the
reported  cost is a per Unit cost.  For purposes of this  Schedule  13D, the net
investment cost attributes all the Unit cost to the related Share.

                              Page 33 of 39 Pages
<PAGE>


                                   SCHEDULE C

               FARALLON CAPITAL INSTITUTIONAL PARTNERS II, L.P.


                                 NO. OF SHARES9
                                 PURCHASED (P)              PRICE
       TRADE DATE                 OR SOLD (S)             PER SHARE10

        12-15-99                   1,400 (P)               $5.13
        12-17-99                    100 (P)                $5.03
        12-17-99                    400 (P)                $5.13













- -----------------------
     9 All  the  Shares  were  acquired  as  part of the  Units  at the  time of
purchase.

     10 As the Shares  traded as part of the Units at the time of purchase,  the
reported  cost is a per Unit cost.  For purposes of this  Schedule  13D, the net
investment cost attributes all the Unit cost to the related Share.


                              Page 34 of 39 Pages
<PAGE>


                                   SCHEDULE D

              FARALLON CAPITAL INSTITUTIONAL PARTNERS III, L.P.


                                 NO. OF SHARES11
                                 PURCHASED (P)              PRICE
       TRADE DATE                 OR SOLD (S)             PER SHARE12

        12-15-99                   1,800 (P)               $5.13
        12-17-99                    200 (P)                $5.03
        12-17-99                    600 (P)                $5.13











- ------------------------
     11 All  the  Shares  were  acquired  as part of the  Units  at the  time of
purchase.

     12 As the Shares  traded as part of the Units at the time of purchase,  the
reported  cost is a per Unit cost.  For purposes of this  Schedule  13D, the net
investment cost attributes all the Unit cost to the related Share.


                              Page 35 of 39 Pages
<PAGE>


                                   SCHEDULE E

                             TINICUM PARTNERS, L.P.


                                 NO. OF SHARES13
                                 PURCHASED (P)              PRICE
       TRADE DATE                 OR SOLD (S)             PER SHARE14

        12-15-99                    500 (P)                $5.13
        12-17-99                    200 (P)                $5.13














- ------------------------
     13 All  the  Shares  were  acquired  as part of the  Units  at the  time of
purchase.

     14 As the Shares  traded as part of the Units at the time of purchase,  the
reported  cost is a per Unit cost.  For purposes of this  Schedule  13D, the net
investment cost attributes all the Unit cost to the related Share.


                              Page 36 of 39 Pages
<PAGE>



                                   SCHEDULE F

                       FARALLON CAPITAL MANAGEMENT, L.L.C.


                                 NO. OF SHARES15
                                 PURCHASED (P)              PRICE
       TRADE DATE                 OR SOLD (S)             PER SHARE16

        12-15-99                  12,600 (P)               $5.13
        12-17-99                    900 (P)                $5.03
        12-17-99                   3,700 (P)               $5.13

        12-15-99                   1,800 (P)               $5.13
        12-17-99                    100 (P)                $5.03
        12-17-99                    500 (P)                $5.13













- ------------------------
     15 All  the  Shares  were  acquired  as part of the  Units  at the  time of
purchase.

     16 As the Shares  traded as part of the Units at the time of purchase,  the
reported  cost is a per Unit cost.  For purposes of this  Schedule  13D, the net
investment cost attributes all the Unit cost to the related Share.


                              Page 37 of 39 Pages
<PAGE>



                                  EXHIBIT INDEX

EXHIBIT 1                      Joint Acquisition Statement Pursuant to Rule 13D-
                               (f)(1)
















                              Page 38 of 39 Pages

<PAGE>



                                                                       EXHIBIT 1
                                                                              to
                                                                    SCHEDULE 13D

                           JOINT ACQUISITION STATEMENT
                           PURSUANT TO RULE 13D-(f)(1)

     The  undersigned  acknowledge  and agree that the  foregoing  statement  on
Schedule  13D is  filed  on  behalf  of each of the  undersigned  and  that  all
subsequent amendments to this statement on Schedule 13D shall be filed on behalf
of each of the  undersigned  without the  necessity of filing  additional  joint
acquisition   statements.   The  undersigned  acknowledge  that  each  shall  be
responsible for the timely filing of such  amendments,  and for the completeness
and accuracy of the information concerning him, her or it contained therein, but
shall not be responsible  for the  completeness  and accuracy of the information
concerning the other  entities or persons,  except to the extent that he, she or
it knows or has reason to believe that such information is inaccurate.

Dated: January 11, 2000

                        /s/ Thomas F. Steyer
                        ----------------------------------------
                        FARALLON PARTNERS, L.L.C.,
                        on its own behalf and as General Partner of
                        FARALLON CAPITAL PARTNERS, L.P.,
                        FARALLON CAPITAL INSTITUTIONAL PARTNERS, L.P.,
                        FARALLON CAPITAL INSTITUTIONAL PARTNERS II, L.P.,
                        FARALLON CAPITAL INSTITUTIONAL PARTNERS III, L.P.,
                        And TINICUM PARTNERS, L.P.,
                        By Thomas F. Steyer,
                        Senior Managing Member


                        /s/ Thomas F. Steyer
                        ----------------------------------------
                        FARALLON CAPITAL MANAGEMENT, L.L.C.,
                        By Thomas F. Steyer,
                        Senior Managing Member


                        /s/ Thomas F. Steyer
                        ----------------------------------------
                        Thomas F. Steyer, individually and as attorney-in-fact
                        for  each of  Enrique  H.  Boilini,  David  I.  Cohen,
                        Joseph F. Downes, William F. Duhamel, Fleur E. Fairman,
                        Jason M. Fish, Andrew  B.  Fremder,  Richard  B. Fried,
                        William F. Mellin, Stephen L. Millham, Meridee A. Moore
                        and Mark C. Wehrly.




                              Page 39 of 39 Pages



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