EPOCH BIOSCIENCES INC
POS AM, EX-23.1, 2000-12-28
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>   1

                                                                    Exhibit 23.1


                               CONSENT OF KPMG LLP
The Board of Directors
Epoch Biosciences, Inc.:

We consent to the use of our report incorporated herein by reference and to the
reference to our firm under the heading "Experts" in the prospectus.



KPMG LLP



Seattle, Washington
December 28, 2000




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