MERRILL LYNCH COLORADO MUNICIPAL BOND FUND OF THE MLMSMST
497J, 1994-04-20
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                 MERRILL LYNCH COLORADO MUNICIPAL BOND FUND OF
               MERRILL LYNCH MULTI-STATE MUNICIPAL SERIES TRUST


                                         April 18, 1994

VIA ELECTRONIC FILING
- ---------------------

Securities and Exchange Commission
450 Fifth Street, N.W.
Judiciary Plaza
Washington, D.C. 20549

Attention: Division of Investment Management

           Re:  Merrill Lynch Colorado Municipal Bond    
                Fund of Merrill Lynch Multi-State        
                Municipal Series Trust                   
                Pre-Effective Amendment No. 1 to the     
                Registration Statement on Form N-1A      
                (Securities Act File No. 33-50051;       
                Investment Company Act File No. 811-4375)
                ----------------------------------------- 

Ladies and Gentlemen:

     Pursuant to Rule 497(j) under the Securities Act of 1933, as amended (the 
"1933 Act"), Merrill Lynch Colorado Municipal Bond Fund (the "Fund") of Merrill 
Lynch Multi-State Municipal Series Trust hereby certifies that:

     (1)  the forms of prospectus and statement of additional information that  
          would have been filed pursuant to Rule 497(e) under the 1933 Act would
          not have differed from that contained in Post-Effective Amendment No.
          1 (the "Amendment") to the Fund's Registration Statement on Form N-1A
          (the "Registration Statement"), constituting the most recent amendment
          to the Fund's Registration Statement; and

     (2)  the text of the Amendment to the Fund's Registration Statement was    
          filed electronically with the Securities and Exchange Commission on
          April 13, 1994.

                         Very truly yours,
                                                                                
                         MERRILL LYNCH COLORADO MUNICIPAL BOND
                              FUND OF MERRILL LYNCH MULTI-STATE
                              MUNICIPAL SERIES TRUST

                         By:  /s/ Jerry Weiss
                             ----------------------------------
                                  Jerry Weiss
                                  Secretary
     


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