MERRILL LYNCH COLORADO MUNICIPAL BOND FUND OF THE MLMSMST
24F-2NT, 1996-09-24
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			 U.S. Securities and Exchange Commission
				  Washington, D.C.  20549

					  Form 24F-2
			    Annual Notice of Securities Sold
				 Pursuant to Rule 24f-2




1.  Name and address of Issuer:

    Merrill Lynch Multi-State Municipal Series Trust:
        Merrill Lynch Colorado Municipal Bond Fund
    P.O. Box 9011
    Princeton, N.J.  08543-9011


2.  Name of each series or class of funds for which this notice
    is filed:

    Merrill Lynch Colorado Municipal Bond Fund - Class A
    Merrill Lynch Colorado Municipal Bond Fund - Class B
    Merrill Lynch Colorado Municipal Bond Fund - Class C
    Merrill Lynch Colorado Municipal Bond Fund - Class D

3.  Investment Company Act File Number:   811-4375

    Securities Act File Number:   33-50051


4.  Last day of fiscal year for which this notice is filed:

		 July 31, 1996   

5.  Check box if this notice is being filed more than 180 days 
    after the close of the issuer's fiscal year for purposes of
    reporting securities sold after the close of the fiscal year 
    but before termination of the issuer's 24f-2 declaration:
	
		     [  ]

6.  Date of termination of issuer's declaration under rule 
    24f-2(a)(1), if applicable :



7.  Number and amount of securities of the same class or series 
    which had been registered under the Securities Act of 1933
    other than pursuant to rule 24f-2 in a prior fiscal year,
    but which remained unsold at the beginning of the 
    fiscal year:

			0 shares            


8.  Number and amount of securities registered during the fiscal
    year other than pursuant to rule 24f-2:


			0 shares          


9.  Number and aggregate sale price of securities sold during 
    the fiscal year:

		 767,753 shares              $7,335,316


10.  Number and aggregate sale price of securities sold during 
     the fiscal year in reliance upon registration pursuant to 
     rule 24f-2:

		767,753 shares              $7,335,316



11.  Number and aggregate sale price of securities issued during 
     the fiscal year in connection with dividend reinvestment
     plans, if applicable :


		 56,414 shares              $  537,485


12.  Calculation of registration fee:
     
     (i)   Aggregate sale price of securities 
	   sold during the fiscal year in
	   reliance on rule 24f-2 
	   (from Item 10):                          $7,335,316

     (ii)  Aggregate price of shares issued
	   in connection with dividend		  
	   reinvestment plans (from Item
	   11, if applicable):                    + $  537,485

     (iii)Aggregate price of shares redeemed 	  
	  or repurchased during the fiscal	  
	  year (if applicable):                   - $6,467,031

     (iv) Aggregate price of shares redeemed 
	  or repurchased and previously
	  applied as a reduction to 
	  filing fees pursuant to rule
	  24e-2 (if applicable):                  + $0

     (v)  Net aggregate price of securities
	  sold and issued during the 
	  fiscal year in reliance upon
	  rule 24f-2 [line (i), plus line (ii),     $1,405,770
	  less line (iii), plus line (iv)]
	  (if applicable):

     (vi) Multiplier prescribed by Section
	  6(b) of the Securities Act of
	  1933 or other applicable law or
	  regulation :                          x    1/2900

     (vii)Fee due [line (i) or line (v)
	  multiplied by line (vi)]:                 $484.75




13.  Check box if fees are being remitted to the Commission's
     lockbox depository as described in section 3a of the 
     Commission's Rules of Informal and Other Procedures
     (17 CFR 202.3a).
		 
		       [X]

     Date of mailing or wire transfer of filing fees to the
     Commission's lockbox depository:

		September 21, 1996

			       SIGNATURES

     This report has been signed below by the following persons
     on behalf of the issuer and in the capacities and on the
     dates indicated.


     By 

	/s/Jaclyn Scheck
	Jaclyn Scheck, Assistant Secretary
				

    Date September 21, 1996
    






September 24, 1996



Merrill Lynch Multi-State Municipal Series Trust
P.O. Box 9011
Princeton, New Jersey  08543-9011

Dear Sir or Madam:

     This opinion is furnished in connection with 
the notice (the "Notice") to be filed by Merrill Lynch 
Multi-State Municipal Series Trust, a Massachusetts 
business trust (the "Trust"), with the Securities and 
Exchange Commission pursuant to Rule 24f-2
under the Investment Company Act of 1940, as 
amended.  The Notice is being filed to make definite 
the registration under the Securities Act of 1933, as 
amended, of 11,316,957 shares of beneficial interest, 
par value $0.10 per share, of the Trust (the "Shares") 
which were sold during the Trust's fiscal year ended
July 31, 1996.  The Shares consist of 986,390 shares 
of beneficial interest of Merrill Lynch Pennsylvania 
Municipal Bond Fund (the "Pennsylvania Fund"); 
266,892 shares of beneficial interest of Merrill Lynch 
New Jersey Municipal Bond Fund (the "New Jersey 
Fund"); 2,147,650 shares of beneficial interest of
Merrill Lynch Florida Municipal Bond Fund (the 
"Florida Fund"); 1,200,134 shares of beneficial 
interest of Merrill Lynch Ohio Municipal Bond Fund 
(the "Ohio Fund"); 240,664 shares of beneficial 
interest of the Merrill Lynch Arizona Municipal Bond 
Fund (the "Arizona Fund"); 479,662 shares of 
beneficial interest of the Merrill Lynch North Carolina 
Municipal Bond Fund (the "North Carolina Fund"); 
1,774,823 shares of beneficial interest of the Merrill 
Lynch Michigan Municipal Bond Fund (the "Michigan
Fund"); 208,865 shares of beneficial interest of the 
Merrill Lynch Oregon Municipal Bond Fund (the 
"Oregon Fund"); 1,430,784 shares of beneficial 
interest of the Merrill Lynch Connecticut Municipal 
Bond Fund (the "Connecticut Fund"); 1,035,759 
shares of beneficial interest of the Merrill Lynch 
Maryland Municipal Bond Fund (the "Maryland 
Fund"); 532,204 shares of beneficial interest of 
the Merrill Lynch New Mexico Municipal Bond Fund 
(the "New Mexico Fund"); 767,753 shares of 
beneficial interest of the Merrill Lynch Colorado 
Municipal Bond Fund (the "Colorado Fund"); and 
245,377 shares of beneficial interest of the Merrill 
Lynch Arkansas Municipal Bond Fund (the 
"Arkansas Fund").  The Pennsylvania, New Jersey, 
Florida, Minnesota, Massachusetts, Texas, Ohio, 
Arizona, North Carolina, Michigan, Oregon,
Connecticut, Maryland, New Mexico, Colorado and 
Arkansas Funds comprise 16 of the 17 series of the 
Trust currently offering their shares to the public.

     As counsel for the Trust, we are familiar with the
proceedings taken by it in connection with the 
authorization, issuance and sale of the Shares.  In 
addition, we have examined and are familiar with the 
Declaration of Trust of the Trust, the By-Laws of the 
Trust and such other documents as we have deemed
relevant to the matters referred to in this opinion.

     Based upon the foregoing, we are of the opinion 
that the Shares were legally issued, fully paid and 
non-assessable.

     In rendering this opinion, we have relied as to 
matters of Massachusetts law upon an opinion of 
Bingham, Dana & Gould, dated September 19, 1996, 
rendered to the Trust.

     We hereby consent to the filing of this opinion with 
the Securities and Exchange Commission as an 
attachment to the Notice.

Very truly yours,












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