MERRILL LYNCH COLORADO MUNICIPAL BOND FUND OF THE MLMSMST
N-30D, 1996-03-26
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<PAGE>


MERRILL LYNCH
COLORADO
MUNICIPAL
BOND FUND







FUND LOGO







Semi-Annual Report

January 31, 1996



Officers and Trustees

Arthur Zeikel, President and Trustee
James H. Bodurtha, Trustee
Herbert I. London, Trustee
Robert R. Martin, Trustee
Joseph L. May, Trustee
Andre F. Perold, Trustee
Terry K. Glenn, Executive Vice President
Donald C. Burke, Vice President
Vincent R. Giordano, Vice President
Kenneth A. Jacob, Vice President
Hugh T. Hurley, Portfolio Manager
Gerald M. Richard, Treasurer
Jerry Weiss, Secretary


Custodian
State Street Bank and Trust Company
P.O. Box 351
Boston, MA 02101
<PAGE>

Transfer Agent
Merrill Lynch Financial Data Services, Inc.
4800 Deer Lake Drive East
Jacksonville, FL 32246-6484
(800) 637-3863











This report is not authorized for use as an offer of sale or a
solicitation of an offer to buy shares of the Fund unless
accompanied or preceded by the Fund's current prospectus. Past
performance results shown in this report should not be considered a
representation of future performance. Investment return and
principal value of shares will fluctuate so that shares, when
redeemed, may be worth more or less than their original cost.
Statements and other information herein are as dated and are subject
to change.



Merrill Lynch Colorado
Municipal Bond Fund
Merrill Lynch Multi-State
Municipal Series Trust
Box 9011
Princeton, NJ
08543-9011



TO OUR SHAREHOLDERS
<PAGE>
Although the partial shutdown of the US Government curtailed the
release of most economic data in the latter part of the six-month
period ended January 31, 1996, it was nonetheless apparent that
gross domestic product (GDP) growth was losing momentum. Consumer
spending is barely growing, the industrial sector is at a virtual
standstill and, despite lower mortgage rates, there is little or no
pick-up in housing activity. With inflationary pressures subdued,
the Federal Reserve Board responded to the slowing economy by
continuing to modestly lower short-term interest rates.
Historically, it has taken some time for shifts in monetary policy
to have an impact on economic growth. Therefore, the Federal Reserve
Board's gradual shift to lowering interest rates, which began early
last year, may not be reflected in a pick-up in real economic growth
until later this year.

The impasse between the Clinton Administration and Congress over the
Federal budget continues, although both sides have made concessions
since the debate began. It appears that investors are currently
focusing on the progress that has been made rather than on the
differences that remain. Initially, President Clinton proposed
deficits of about $190 billion annually through fiscal year 2002,
but now proposes balanced budgets, as do the Republicans. Current
indications are that a piecemeal budget accord is the most likely
outcome. Even without the proposed policy changes, it appears that
the US Federal budget deficit would remain stable at about 2% of GDP
for the rest of the decade. This would be far better than is the
case for most Group of Seven industrial nations, and for the United
States would represent a great improvement over the last 15 years.
Although this may fall short of investors' best expectations, it
appears that the Federal budget debate over the past year has
resulted in a trend toward a more conservative fiscal policy.

The Municipal Market
The municipal bond market rallied strongly during the six months
ended January 31, 1996. Long-term, tax-exempt revenue bond yields,
as measured by the Bond Buyer Revenue Bond Index, declined over 65
basis points (0.65%) to end the January period at 5.69%. Continued
weak economic conditions coupled with low inflation fostered a very
positive environment for almost all fixed-income investments during
the last three months of 1995. Long-term US Treasury bond yields
also declined approximately 65 basis points to 6.00% by January 31,
1996. Both US Treasury and long-term tax-exempt bond yields are near
their lowest levels in the past two years.

The municipal bond market had to contend with a number of
difficulties for much of 1995. Various tax reform proposals have
made the future tax advantage of municipal bonds uncertain. This
has, at a minimum, reduced the overall demand for tax-exempt
securities. At the same time, as municipal bond yields declined, tax-
exempt authorities have rushed to issue debt at near historic low
yield levels. During the six-month period ended January 31, 1996,
approximately $90 billion in municipal securities were underwritten,
an increase of over 30% compared to the same period last year.
However, as early 1995 issuance was significantly reduced, the last
12 months issuance of approximately $160 billion remained the same
as that issued a year earlier. Tax-exempt bond yields declined
throughout the six months ended January 31, 1996, despite investor
uncertainty and increased supply pressures.
<PAGE>
It is likely that the municipal market will regain much of the
technical support it enjoyed earlier in 1995. 1995 issuance remained
significantly below levels underwritten in 1993, when over $290
billion in long-term tax-exempt securities were issued. Also,
municipal investors received over $25 billion in bond maturities,
coupon income and early redemptions on January 1, 1996. This $25
billion is almost twice the average monthly issuance for 1995. The
amount of outstanding municipal securities will continue to decline
throughout 1996 and into early 1997. As the uncertainties
surrounding proposed tax reforms are resolved in 1996, the tax-
exempt bond market's renewed technical position should provide
support to municipal bond prices.

Many of the features that made tax-exempt products attractive to
investors last year are still in place. Long-term, A-rated municipal
revenue bonds continue to yield well over 90% of comparable US
Treasury bond yields. Historically, analysts have considered yields
in excess of 82% attractive for long-term investors. For example,
currently available tax-exempt bond yields generate taxable
equivalent yields in excess of 8.50% for an investor in the 36%
Federal income tax bracket. While the uncertainties regarding
potential changes in current tax law remain, it appears that, at
current price levels, bond investors have discounted at least some
of the uncertainty.

Looking ahead, it may be unreasonable to expect to duplicate the
double-digit returns produced by most tax-exempt issues in 1995,
given current municipal bond yields. Municipal bond yields would
have to decline to levels not seen since the 1960s in order to
generate such significant returns in the coming years. While the
current economic environment may still justify additional declines
in interest rates, it may be prudent to expect some period of
consolidation before the interest rate decline resumes. Tax-exempt
bond market performance in 1996 is likely to be generated more by
enhancing current income and limiting credit risk than by
significant interest rate declines.

Portfolio Strategy
Merrill Lynch Colorado Municipal Bond Fund continued to benefit from
lower interest rates and higher bond prices. Throughout the six
months ended January 31, 1996, the Fund remained fully invested, and
we focused our investments on high-quality performance-oriented
municipal bonds. Credit quality remains a factor when considering
Fund investments, as 95% of the portfolio's total assets are
currently rated A or better by at least one of the major rating
services.
<PAGE>
Since the Fund commenced operations two years ago, we have
experienced wide swings in interest rates. During the six-month
period ended January 31, 1996, the Fund capitalized on falling
interest rates. If interest rates continue to fall during the
upcoming months as expected, a sizable percentage of the portfolio
may be prerefunded to benefit shareholders.

While growth of the Fund has slowed, demand for Colorado municipal
bonds remained robust. In the upcoming months, we will seek to
enhance the total return to our shareholders without sacrificing
yield or credit quality.

In Conclusion
We appreciate your ongoing interest in Merrill Lynch Colorado
Municipal Bond Fund, and we look forward to serving your investment
needs and objectives in the months and years to come.

Sincerely,







(Arthur Zeikel)
Arthur Zeikel
President







(Vincent R. Giordano)
Vincent R. Giordano
Vice President







(Hugh T. Hurley III)
Hugh T. Hurley III
Portfolio Manager

<PAGE>

March 8, 1996



We are pleased to announce that Hugh T. Hurley III is responsible
for the day-to-day management of Merrill Lynch Colorado Municipal
Bond Fund. Mr. Hurley has been employed by Merrill Lynch Asset
Management, L.P. (an affiliate of the Fund's investment adviser)
since 1996 as Vice President and since 1993 as Assistant Vice
President. Prior thereto, he was a Municipal Bond Broker with Titus
and Donnelly Municipal Bond Brokers from 1990 to 1993.



PERFORMANCE DATA


About Fund Performance

Investors are able to purchase shares of the Fund through the
Merrill Lynch Select Pricing SM System, which offers four pricing
alternatives:

* Class A Shares incur a maximum initial sales charge (front-end load)
  of 4% and bear no ongoing distribution or account maintenance fees.
  Class A Shares are available only to eligible investors.

* Class B Shares are subject to a maximum contingent deferred sales
  charge of 4% if redeemed during the first year, decreasing 1% each
  year thereafter to 0% after the fourth year. In addition, Class B
  Shares are subject to a distribution fee of 0.25% and an account
  maintenance fee of 0.25%. These shares automatically convert to
  Class D Shares after approximately 10 years.

* Class C Shares are subject to a distribution fee of 0.35% and an
  account maintenance fee of 0.25%. In addition, Class C Shares are
  subject to a 1% contingent deferred sales charge if redeemed within
  one year of purchase.
 
* Class D Shares incur a maximum initial sales charge of 4% and an
  account maintenance fee of 0.10% (but no distribution fee).

None of the past results shown should be considered a representation
of future performance. Investment return and principal value of
shares will fluctuate so that shares, when redeemed, may be worth
more or less than their original cost. Dividends paid to each class
of shares will vary because of the different levels of account
maintenance, distribution and transfer agency fees applicable to
each class, which are deducted from the income available to be paid
to shareholders.
<PAGE>




<TABLE>
Recent Performance Results
<CAPTION>
                                                                               12 Month    3 Month
                                                1/31/96  10/31/95    1/31/95   % Change    % Change
<S>                                              <C>       <C>        <C>       <C>         <C>
Class A Shares*                                  $9.82     $9.54      $9.07     + 8.27%     +2.94%
Class B Shares*                                   9.82      9.54       9.07     + 8.27      +2.94
Class C Shares*                                   9.82      9.55       9.08     + 8.15      +2.83
Class D Shares*                                   9.81      9.54       9.07     + 8.16      +2.83
Class A Shares--Total Return*                                                   +14.36(1)   +4.26(2)
Class B Shares--Total Return*                                                   +13.78(3)   +4.13(4)
Class C Shares--Total Return*                                                   +13.52(5)   +4.00(6)
Class D Shares--Total Return*                                                   +14.13(7)   +4.13(8)
Class A Shares--Standardized 30-day Yield         4.57%
Class B Shares--Standardized 30-day Yield         4.26%
Class C Shares--Standardized 30-day Yield         4.16%
Class D Shares--Standardized 30-day Yield         4.48%


<FN>
  *Investment results shown do not reflect sales charges; results
   shown would be lower if a sales charge was included.
(1)Percent change includes reinvestment of $0.519 per share ordinary
   income dividends.
(2)Percent change includes reinvestment of $0.125 per share ordinary
   income dividends.
(3)Percent change includes reinvestment of $0.471 per share ordinary
   income dividends.
(4)Percent change includes reinvestment of $0.113 per share ordinary
   income dividends.
(5)Percent change includes reinvestment of $0.460 per share ordinary
   income dividends.
(6)Percent change includes reinvestment of $0.111 per share ordinary
   income dividends.
(7)Percent change includes reinvestment of $0.509 per share ordinary
   income dividends.
(8)Percent change includes reinvestment of $0.123 per share ordinary
   income dividends.
</TABLE>


PERFORMANCE DATA (continued)
<PAGE>
<TABLE>
Performance Summary--Class A Shares
<CAPTION>
                           Net Asset Value        Capital Gains
Period Covered          Beginning     Ending       Distributed          Dividends Paid*     % Change**
<S>                      <C>          <C>              <C>                  <C>              <C>
11/26/93--12/31/93       $10.00       $10.14           --                   $0.042           + 1.82%
1994                      10.14         8.81           --                    0.512           - 8.19
1995                       8.81         9.80           --                    0.521           +17.56
1/1/96--1/31/96            9.80         9.82           --                    0.029           + 0.60
                                                                            ------
                                                                      Total $1.104

                                                      Cumulative total return as of 1/31/96: +10.56%**

<FN>
 *Figures may include short-term capital gains distributions.
**Figures assume reinvestment of all dividends and capital gains
  distributions at net asset value on the payable date, and do not
  include sales charge; results would be lower if sales charge was
  included.
</TABLE>


<TABLE>
Performance Summary--Class B Shares
<CAPTION>
                           Net Asset Value        Capital Gains
Period Covered          Beginning     Ending       Distributed          Dividends Paid*     % Change**
<S>                      <C>          <C>              <C>                  <C>              <C>
11/26/93--12/31/93       $10.00       $10.14           --                   $0.037           + 1.77%
1994                      10.14         8.81           --                    0.465           - 8.66
1995                       8.81         9.80           --                    0.474           +16.97
1/1/96--1/31/96            9.80         9.82           --                    0.026           + 0.57
                                                                            ------
                                                                      Total $1.002

                                                      Cumulative total return as of 1/31/96: + 9.35%**

<FN>
 *Figures may include short-term capital gains distributions.
**Figures assume reinvestment of all dividends and capital gains
  distributions at net asset value on the payable date, and do not
  reflect deduction of any sales charge; results would be lower if
  sales charge was deducted.
</TABLE>

<PAGE>
<TABLE>
Performance Summary--Class C Shares
<CAPTION>
                           Net Asset Value        Capital Gains
Period Covered           Beginning     Ending      Distributed          Dividends Paid*     % Change**
<S>                       <C>          <C>             <C>                  <C>              <C>
10/21/94--12/31/94        $9.03        $8.81           --                   $0.077           - 1.57%
1995                       8.81         9.80           --                    0.462           +16.83
1/1/96--1/31/96            9.80         9.82           --                    0.025           + 0.57
                                                                            ------
                                                                      Total $0.564

                                                      Cumulative total return as of 1/31/96: +15.65%**

<FN>
 *Figures may include short-term capital gains distributions.
**Figures assume reinvestment of all dividends and capital gains
  distributions at net asset value on the payable date, and do not
  reflect deduction of any sales charge; results would be lower if
  sales charge was deducted.
</TABLE>


PERFORMANCE DATA (concluded)

<TABLE>
Performance Summary--Class D Shares
<CAPTION>
                           Net Asset Value        Capital Gains
Period Covered          Beginning     Ending       Distributed          Dividends Paid*     % Change**
<S>                       <C>          <C>             <C>                  <C>              <C>
10/21/94--12/31/94        $9.03        $8.81           --                   $0.097           - 1.34%
1995                       8.81         9.80           --                    0.512           +17.45
1/1/96--1/31/96            9.80         9.81           --                    0.028           + 0.49
                                                                            ------
                                                                      Total $0.637

                                                      Cumulative total return as of 1/31/96: +16.45%**

<FN>
 *Figures may include short-term capital gains distributions.
**Figures assume reinvestment of all dividends and capital gains
  distributions at net asset value on the payable date, and do not
  include sales charge; results would be lower if sales charge was
  included.
</TABLE>



Average Annual Total Return
<PAGE>
                                    % Return Without  % Return With
                                       Sales Charge    Sales Charge**

Class A Shares*

Year Ended 12/31/95                       +17.56%        +12.86%
Inception (11/26/93)
through 12/31/95                          + 4.61         + 2.59

[FN]
 *Maximum sales charge is 4%.
**Assuming maximum sales charge.



                                        % Return        % Return
                                       Without CDSC    With CDSC**

Class B Shares*

Year Ended 12/31/95                       +16.97%        +12.97%
Inception (11/26/93)
through 12/31/95                          + 4.08         + 3.17

[FN]
 *Maximum contingent deferred sales charge is 4% and is reduced to 0%
  after 4 years.
**Assuming payment of applicable contingent deferred sales charge.



                                        % Return        % Return
                                       Without CDSC    With CDSC**

Class C Shares*

Year Ended 12/31/95                       +16.83%        +15.83%
Inception (10/21/94)
through 12/31/95                          +12.41         +12.41

[FN]
 *Maximum contingent deferred sales charge is 1% and is reduced to 0%
  after 1 year.
**Assuming payment of applicable contingent deferred sales charge.



                                     % Return Without % Return With
                                       Sales Charge    Sales Charge**

Class D Shares*

Year Ended 12/31/95                       +17.45%        +12.75%
Inception (10/21/94)
through 12/31/95                          +13.13         + 9.33
<PAGE>
[FN]
 *Maximum sales charge is 4%.
**Assuming maximum sales charge.



PORTFOLIO ABBREVIATIONS


To simplify the listings of Merrill Lynch Colorado Municipal Bond
Fund's portfolio holdings in the Schedule of Investments, we have
abbreviated the names of many of the securities according to the
list at right.

AMT     Alternative Minimum Tax (subject to)
IDR     Industrial Development  Revenue Bonds
S/F     Single-Family
UT      Unlimited Tax
VRDN    Variable Rate Demand Notes



<TABLE>
SCHEDULE OF INVESTMENTS                                                                                   (in Thousands)
<CAPTION>
S&P     Moody's        Face                                                                                      Value
Ratings Ratings       Amount                                  Issue                                            (Note 1a)

Colorado--98.9%
<S>      <S>         <C>      <S>                                                                               <C>
A+       A1          $1,000   Adams and Arapahoe Counties, Colorado, Joint School District Number
                              28 (Aurora), UT, Series C, 5.75% due 12/01/2006                                   $  1,080

AAA      Aaa          1,000   Alamosa and Conejos Counties, Colorado, School District Number 11,
                              5% due 12/01/2015 (c)                                                                  977

AAA      Aaa          1,000   Arapahoe County, Colorado, Capital Improvement Trust Fund, Highway Revenue
                              Bonds(E470 Vehicle Registration), Series A, 6.15% due 8/31/2026 (b)                  1,080

AA       Aa           1,400   Arapahoe County, Colorado, School District Number 5 (Cherry Creek),
                              Series B, 5.15% due 12/15/2015                                                       1,388

AAA      Aaa          1,175   Arvada, Colorado, Sales and Use Tax Revenue Refunding and Improvement
                              Bonds, 6.25% due 12/01/2017 (d)                                                      1,263

AAA      Aaa          1,000   Auraria, Colorado, Higher Education Center Revenue Bonds (Student Fee),
                              Series B, 6.50% due 11/01/2016(c)                                                    1,087
<PAGE>
AAA      Aaa            500   Bayfield County, Colorado, Joint School District Number 10, Building Revenue
                              Bonds, UT, Series R, 6.65% due 6/01/2015 (b)                                           567

                              Colorado Health Facilities Authority Revenue Bonds:
AAA      Aaa          1,000     Refunding (Boulder Community Hospital), Series B, 5.875% due 10/01/2023 (b)        1,038
NR*      Baa1           500     (Swedish Medical Center Project), Series A, 6.80% due 1/01/2003 (f)                  580

NR*      Aa             955   Colorado Housing Financing Authority, Refunding Bonds, Series D-II, 8.125%
                              due 6/01/2025                                                                        1,093

NR*      Aa             950   Colorado Housing Financing Authority, S/F Program, AMT, Senior Series F,
                              8.625% due 6/01/2025 (e)                                                             1,091

A+       A1             800   Colorado Springs, Colorado, Revenue Bonds (Colorado College Project),
                              5.125% due 6/01/2016                                                                   783

                              Colorado Springs, Colorado, Utilities Revenue Bonds, Series A:
AA       Aa           1,125     6.10% due 11/15/2024                                                               1,191
AA       Aa             500     Refunding, 6.50% due 11/15/2015                                                      545
</TABLE>


<TABLE>
SCHEDULE OF INVESTMENTS (concluded)                                                                       (in Thousands)
<CAPTION>
S&P     Moody's        Face                                                                                      Value
Ratings Ratings       Amount                                  Issue                                            (Note 1a)

Colorado (concluded)
<S>      <S>         <C>      <S>                                                                               <C>      
AA       Aa          $1,000   Colorado Water Resource Power Development Authority, Clean Water Revenue
                              Bonds, Series A, 6.30% due 9/01/2014                                              $  1,078

BBB      Baa            500   Denver, Colorado, City and County Airport Revenue Bonds, AMT, Series D,
                              7.75% due 11/15/2013                                                                   596

                              Denver, Colorado, City and County School District  Number 1, Refunding Bonds,
                              Series A:
A+       A            1,000     6.50% due 6/01/2010                                                                1,154
A+       A            2,000     6.50% due 12/01/2010                                                               2,323

AAA      Aaa          2,750   Douglas County, Colorado, School District Number 1 Revenue Bonds (Douglas
                              and Elbert Counties Improvement Project), Series A, 6.50% due 12/15/2016 (b)         3,090

NR*      Aa1          1,000   El Paso County, Colorado, School District Number 12 Revenue Bonds (Cheyenne
                              Mountain), UT, 6.65% due 9/15/2014                                                   1,111

AAA      Aaa          1,000   Garfield, Pitkin and Eagle Counties, Colorado, School District Number 1
                              Revenue Bonds(Roaring Fork), UT, 6.60% due 6/15/2004 (b)(f)                          1,157

AAA      Aaa          1,000   Gunnison Watershed, Colorado, School District Number 1 Revenue Bonds, UT,
                              5% due 12/01/2015 (b)                                                                  977
<PAGE>
AAA      Aaa          1,500   La Plata County, Colorado, School District Number 9 Revenue Bonds (R Durango),
                              UT, 6.60% due 11/01/2017 (d)                                                         1,656

A1+      NR*            500   Pitkin County, Colorado, IDR, Refunding (Aspen Skiing Co. Project), VRDN, AMT,
                              Series B, 4% due 4/01/2014 (a)                                                         500

NR*      A              750   Pitkin County, Colorado, Refunding and Improvement Bonds, UT, 6.875% due
                              12/01/2024                                                                             836

AAA      Aaa          1,000   Poudre County, Colorado, Poudre County, District Hospital Revenue Bonds,
                              6.625% due 12/01/2001 (c)(f)                                                         1,134

AAA      Aaa          1,000   Summit County, Colorado, School District Number 1 Revenue Bonds (Summit),
                              UT, 6.70% due 12/01/2014 (d)                                                         1,135

Total Investments (Cost--$28,437)--98.9%                                                                          30,510

Other Assets Less Liabilities--1.1%                                                                                  354
                                                                                                                --------
Net Assets--100.0%                                                                                              $ 30,864
                                                                                                                ========
<FN>
(a)The interest rate is subject to change periodically based upon
   prevailing market rates. The interest rate shown is the rate in
   effect at January 31, 1996.
(b)MBIA Insured.
(c)AMBAC Insured.
(d)FGIC Insured.
(e)FHA Insured.
(f)Prerefunded.
  *Not Rated.

See Notes to Financial Statements.
</TABLE>



FINANCIAL INFORMATION

<PAGE>
<TABLE>
Statement of Assets and Liabilities as of January 31, 1996
<CAPTION>
<S>                 <S>                                                                    <C>              <C>
Assets:             Investments, at value (identified cost--$28,437,116) (Note 1a)                          $ 30,509,816
                    Cash                                                                                          54,802
                    Receivables:
                      Interest                                                             $    355,881
                      Securities sold                                                            30,430
                      Investment adviser (Note 2)                                                10,136          396,447
                                                                                           ------------
                    Deferred organization expenses (Note 1e)                                                      21,217
                    Prepaid expenses and other assets (Note 1e)                                                   47,572
                                                                                                            ------------
                    Total assets                                                                              31,029,854
                                                                                                            ------------

Liabilities:        Payables:
                      Dividends to shareholders (Note 1f)                                        36,375
                      Beneficial interest redeemed                                               27,246
                      Distributor (Note 2)                                                        8,063           71,684
                                                                                           ------------
                    Accrued expenses                                                                              93,806
                                                                                                            ------------
                    Total liabilities                                                                            165,490
                                                                                                            ------------

Net Assets:         Net assets                                                                              $ 30,864,364
                                                                                                            ============

Net Assets          Class A Shares of beneficial interest, $.10 par value, unlimited
Consist of:         number of shares authorized                                                             $     97,554
                    Class B Shares of beneficial interest, $.10 par value, unlimited
                    number of shares authorized                                                                  192,823
                    Class C Shares of beneficial interest, $.10 par value, unlimited
                    number of shares authorized                                                                    4,991
                    Class D Shares of beneficial interest, $.10 par value, unlimited
                    number of shares authorized                                                                   18,941
                    Paid-in capital in excess of par                                                          30,481,458
                    Accumulated realized capital losses on investments--net (Note 5)                          (2,004,103)
                    Unrealized appreciation on investments--net                                                2,072,700
                                                                                                            ------------
                    Net assets                                                                              $ 30,864,364
                                                                                                            ============

Net Asset Value:    Class A--Based on net assets of $9,579,481 and 975,539 shares
                    of beneficial interest outstanding                                                      $       9.82
                                                                                                            ============
                    Class B--Based on net assets of $18,935,612 and 1,928,233 shares
                    of beneficial interest outstanding                                                      $       9.82
                                                                                                            ============
                    Class C--Based on net assets of $490,252 and 49,910 shares
                    of beneficial interest outstanding                                                      $       9.82
                                                                                                            ============
                    Class D--Based on net assets of $1,859,019 and 189,410 shares
                    of beneficial interest outstanding                                                      $       9.81
                                                                                                            ============
See Notes to Financial Statements.
</TABLE>


FINANCIAL INFORMATION (continued)
<PAGE>
<TABLE>
Statement of Operations
<CAPTION>
                                                                                                For the Six Months Ended
                                                                                                        January 31, 1996
<S>                 <S>                                                                    <C>              <C>  
Investment Income   Interest and amortization of premium and discount earned                                $    852,048
(Note 1d):

Expenses:           Investment advisory fees (Note 2)                                      $     81,719
                    Account maintenance and distribution fees--Class B (Note 2)                  45,055
                    Professional fees                                                            26,526
                    Printing and shareholder reports                                             23,039
                    Accounting services (Note 2)                                                 15,148
                    Registration fees (Note 1e)                                                  11,185
                    Transfer agent fees--Class B (Note 2)                                         4,905
                    Amortization of organization expenses (Note 1e)                               3,266
                    Transfer agent fees--Class A (Note 2)                                         2,114
                    Pricing fees                                                                  2,046
                    Custodian fees                                                                1,569
                    Account maintenance and distribution fees--Class C (Note 2)                   1,286
                    Account maintenance fees--Class D (Note 2)                                      742
                    Trustees' fees and expenses                                                     716
                    Transfer agent fees--Class D (Note 2)                                           319
                    Transfer agent fees--Class C (Note 2)                                           122
                    Other                                                                           798
                                                                                           ------------
                    Total expenses before reimbursement                                         220,555
                    Reimbursement of expenses (Note 2)                                         (108,153)
                                                                                           ------------
                    Total expenses after reimbursement                                                           112,402
                                                                                                            ------------
                    Investment income--net                                                                       739,646
                                                                                                            ------------

Realized &          Realized loss on investments--net                                                            (40,188)
Unrealized          Change in unrealized appreciation on investments--net                                      1,310,878
Gain (Loss) on                                                                                              ------------
Investments--Net    Net Increase in Net Assets Resulting from Operations                                    $  2,010,336
(Notes 1b, 1d & 3):                                                                                         ============


                    See Notes to Financial Statements.
</TABLE>


FINANCIAL INFORMATION (continued)

<TABLE>
Statements of Changes in Net Assets
<CAPTION>
<PAGE>
                                                                                             For the
                                                                                            Six Months        For the
                                                                                              Ended          Year Ended
Increase (Decrease) in Net Assets:                                                        Jan. 31, 1996    July 31, 1995
<S>                 <S>                                                                    <C>              <C>
Operations:         Investment income--net                                                 $    739,646     $  1,363,938
                    Realized loss on investments--net                                           (40,188)      (1,161,781)
                    Change in unrealized appreciation/depreciation on investments--net        1,310,878        1,501,199
                                                                                           ------------     ------------
                    Net increase in net assets resulting from operations                      2,010,336        1,703,356
                                                                                           ------------     ------------

Dividends to        Investment income--net:
Shareholders          Class A                                                                  (259,410)        (524,727)
(Note 1f):            Class B                                                                  (431,696)        (795,258)
                      Class C                                                                   (10,010)          (1,891)
                      Class D                                                                   (38,530)         (42,062)
                                                                                           ------------     ------------
                    Net decrease in net assets resulting from dividends to shareholders        (739,646)      (1,363,938)
                                                                                           ------------     ------------

Beneficial Interest Net increase in net assets derived from beneficial interest 
Transactions        transactions                                                              1,296,540        2,801,169
(Note 4):                                                                                  ============     ============

Net Assets:         Total increase in net assets                                              2,567,230        3,140,587
                    Beginning of period                                                      28,297,134       25,156,547
                                                                                           ------------     ------------
                    End of period                                                          $ 30,864,364     $ 28,297,134
                                                                                           ============     ============
                    See Notes to Financial Statements.
</TABLE>


FINANCIAL INFORMATION (concluded)
<PAGE>
<TABLE>
Financial Highlights
<CAPTION>
                                                                       Class A                        Class B
                                                            For the              For the    For the             For the
                                                              Six      For the    Period      Six     For the    Period
The following per share data and ratios have been derived    Months      Year     Nov. 26,   Months     Year     Nov. 26,
from information provided in the financial statements.       Ended      Ended    1993++ to   Ended     Ended    1993++ to
                                                            Jan. 31,   July 31,   July 31,  Jan. 31,  July 31,   July 31,
Increase (Decrease) in Net Asset Value:                       1996       1995       1994      1996      1995       1994
<S>                 <S>                                     <C>        <C>        <C>       <C>       <C>        <C>     
Per Share           Net asset value, beginning of period    $  9.41    $  9.38    $ 10.00   $  9.41   $  9.38    $ 10.00
Operating                                                   -------    -------    -------   -------   -------    -------
Performance:        Investment income--net                      .26        .52        .34       .23       .48        .31
                    Realized and unrealized gain (loss) on
                    investments--net                            .41        .03       (.62)      .41       .03       (.62)
                                                            -------    -------    -------   -------   -------    -------
                    Total from investment operations            .67        .55       (.28)      .64       .51       (.31)
                                                            -------    -------    -------   -------   -------    -------
                    Less dividends from investment 
                    income--net                                (.26)      (.52)      (.34)     (.23)     (.48)      (.31)
                                                            -------    -------    -------   -------   -------    -------
                    Net asset value, end of period          $  9.82    $  9.41    $  9.38   $  9.82   $  9.41    $  9.38
                                                            =======    =======    =======   =======   =======    =======

Total Investment    Based on net asset value per share        7.14%+++   6.20%     (2.83%)+++ 6.87%+++  5.66%     (3.16%)+++
Return:**                                                   =======    =======    =======   =======   =======    =======


Ratios to           Expenses, net of reimbursement             .43%*      .24%       .03%*     .94%*     .76%       .54%*
Average                                                     =======    =======    =======   =======   =======    =======
Net Assets:         Expenses                                  1.16%*     1.40%      1.52%*    1.67%*    1.93%      2.03%*
                                                            =======    =======    =======   =======   =======    =======
                    Investment income--net                    5.29%*     5.71%      5.36%*    4.78%*    5.20%      4.73%*
                                                            =======    =======    =======   =======   =======    =======

Supplemental        Net assets, end of period (in 
Data:               thousands)                              $ 9,579    $ 9,755    $10,634   $18,936   $17,116    $14,522
                                                            =======    =======    =======   =======   =======    =======
                    Portfolio turnover                       33.55%     73.86%     82.71%    33.55%    73.86%     82.71%
                                                            =======    =======    =======   =======   =======    =======

<CAPTION>
                                                                                     Class C              Class D
                                                                               For the    For the     For the   For the
                                                                                 Six       Period       Six      Period
The following per share data and ratios have been derived                       Months    Oct. 21,     Months    Oct. 21,
from information provided in the financial statements.                          Ended    1994++ to     Ended    1994++ to
                                                                               Jan. 31,   July 31,    Jan. 31,   July 31,
Increase (Decrease) in Net Asset Value:                                          1996       1995        1996       1995
<S>                 <S>                                                       <C>        <C>         <C>        <C>
Per Share           Net asset value, beginning of period                      $   9.41   $   9.03    $   9.40   $   9.03
Operating                                                                     --------   --------    --------   --------
Performance:        Investment income--net                                         .23        .35         .25        .40
                    Realized and unrealized gain on investments--net               .41        .38         .41        .37
                                                                              --------   --------    --------   --------
                    Total from investment operations                               .64        .73         .66        .77
                                                                              --------   --------    --------   --------
                    Less dividends from investment income--net                    (.23)      (.35)       (.25)      (.40)
                                                                              --------   --------    --------   --------
                    Net asset value, end of period                            $   9.82   $   9.41    $   9.81   $   9.40
                                                                              ========   ========    ========   ========

Total Investment    Based on net asset value per share                           6.81%+++   8.27%+++    7.09%+++   8.74%+++
Return:**                                                                     ========   ========    ========   ========

Ratios to           Expenses, net of reimbursement                               1.05%*      .95%*       .53%*      .38%*
Average                                                                       ========   ========    ========   ========
Net Assets:         Expenses                                                     1.76%*     2.04%*      1.25%*     1.49%*
                                                                              ========   ========    ========   ========
                    Investment income--net                                       4.66%*     5.01%*      5.18%*     5.66%*
                                                                              ========   ========    ========   ========

Supplemental        Net assets, end of period (in thousands)                  $    490   $    162    $  1,859   $  1,265
Data:                                                                         ========   ========    ========   ========
                    Portfolio turnover                                          33.55%     73.86%      33.55%     73.86%
                                                                              ========   ========    ========   ========
<PAGE>
                 <FN>
                   *Annualized.
                  **Total investment returns exclude the effects of sales loads.
                  ++Commencement of Operations.
                 +++Aggregate total investment return.

                    See Notes to Financial Statements.
</TABLE>



NOTES TO FINANCIAL STATEMENTS

1. Significant Accounting Policies:
Merrill Lynch Colorado Municipal Bond Fund (the "Fund") is part of
Merrill Lynch Multi-State Municipal Series Trust (the "Trust"). The
Fund is registered under the Investment Company Act of 1940 as a non-
diversified, open-end management investment company. These unaudited
financial statements reflect all adjustments which are, in the
opinion of management, necessary to a fair statement of the results
for the interim period presented. All such adjustments are of a
normal recurring nature. The Fund offers four classes of shares
under the Merrill Lynch Select Pricing SM System. Shares of Class A
and Class D are sold with a front-end sales charge. Shares of Class
B and Class C may be subject to a contingent deferred sales charge.
All classes of shares have identical voting, dividend, liquidation
and other rights and the same terms and conditions, except that
Class B, Class C and Class D Shares bear certain expenses related to
the account maintenance of such shares, and Class B and Class C
Shares also bear certain expenses related to the distribution of
such shares. Each class has exclusive voting rights with respect to
matters relating to its account maintenance and distribution
expenditures. The following is a summary of significant accounting
policies followed by the Fund.
<PAGE>
(a) Valuation of investments--Municipal bonds and other portfolio
securities in which the Fund invests are traded primarily in the
over-the-counter municipal bond and money markets and are valued at
the last available bid price in the over-the-counter market or on
the basis of yield equivalents as obtained from one or more dealers
that make markets in the securities. Financial futures contracts and
options thereon, which are traded on exchanges, are valued at their
settlement prices as of the close of such exchanges. Short-term
investments with remaining maturities of sixty days or less are
valued at amortized cost, which approximates market value.
Securities and assets for which market quotations are not readily
available are valued at fair value as determined in good faith by or
under the direction of the Board of Trustees of the Trust, including
valuations furnished by a pricing service retained by the Trust,
which may utilize a matrix system for valuations. The procedures of
the pricing service and its valuations are reviewed by the officers
of the Trust under the general supervision of the Trustees.

(b) Derivative financial instruments--The Fund may engage in various
portfolio strategies to seek to increase its return by hedging its
portfolio against adverse movements in the debt markets. Losses may
arise due to changes in the value of the contract or if the
counterparty does not perform under the contract.

* Financial futures contracts--The Fund may purchase or sell interest
rate futures contracts and options on such futures contracts for the
purpose of hedging the market risk on existing securities or the
intended purchase of securities. Futures contracts are contracts for
delayed delivery of securities at a specific future date and at a
specific price or yield. Upon entering into a contract, the Fund
deposits and maintains as collateral such initial margin as required
by the exchange on which the transaction is effected. Pursuant to
the contract, the Fund agrees to receive from or pay to the broker
an amount of cash equal to the daily fluctuation in value of the
contract. Such receipts or payments are known as variation margin
and are recorded by the Fund as unrealized gains or losses. When the
contract is closed, the Fund records a realized gain or loss equal
to the difference between the value of the contract at the time it
was opened and the value at the time it was closed.

(c) Income taxes--It is the Fund's policy to comply with the
requirements of the Internal Revenue Code applicable to regulated
investment companies and to distribute substantially all of its
taxable income to its shareholders. Therefore, no Federal income tax
provision is required.

(d) Security transactions and investment income--Security
transactions are recorded on the dates the transactions are entered
into (the trade dates). Interest income is recognized on the accrual
basis. Discounts and market premiums are amortized into interest
income. Realized gains and losses on security transactions are
determined on the identified cost basis.

(e) Deferred organization expenses and prepaid registration fees--
Deferred organization expenses are charged to expense on a straight-
line basis over a five-year period. Prepaid registration fees are
charged to expense as the related shares are issued.

(f) Dividends and distributions--Dividends from net investment
income are declared daily and paid monthly. Distributions of capital
gains are recorded on the ex-dividend dates.
<PAGE>
2. Investment Advisory Agreement and
Transactions with Affiliates:
The Fund has entered into an Investment Advisory Agreement with Fund
Asset Management, L.P. ("FAM"). The general partner of FAM is
Princeton Services, Inc. ("PSI"), an indirect wholly-owned
subsidiary of Merrill Lynch & Co., Inc. ("ML & Co."), which is the
limited partner. The Fund has also entered into a Distribution
Agreement and Distribution Plans with Merrill Lynch Funds
Distributor, Inc. ("MLFD" or "Distributor"), a wholly-owned
subsidiary of Merrill Lynch Group, Inc.

FAM is responsible for the management of the Fund's portfolio and
provides the necessary personnel, facilities, equipment and certain
other services necessary to the operations of the Fund. For such
services, the Fund pays a monthly fee based upon the average daily
value of the Fund's net assets at the following annual rates: 0.55%
of the Fund's average daily net assets not exceeding $500 million;
0.525% of average daily net assets in excess of $500 million but not
exceeding $1 billion; and 0.50% of average daily net assets in
excess of $1 billion.  The Investment Advisory Agreement obligates
FAM to reimburse the Fund to the extent the Fund's expenses
(excluding interest, taxes, distribution fees, brokerage fees and
commissions, and extraordinary items) exceed 2.5% of the Fund's
first $30 million of average daily net assets, 2.0% of the next $70
million of average daily net assets, and 1.5% of the average daily
net assets in excess thereof. FAM's obligation to reimburse the Fund
is limited to the amount of the management fee. No fee payment will
be made to FAM during any fiscal year which will cause such expenses
to exceed expense limitations at the time of payment. For the six
months ended January 31, 1996, FAM earned fees of $81,719, all of
which was voluntarily waived. FAM also reimbursed the Fund
additional expenses of $26,434.

Pursuant to the distribution plans (the "Distribution Plans")
adopted by the Fund in accordance with Rule 12b-1 under the
Investment Company Act of 1940, the Fund pays the Distributor
ongoing account maintenance and distribution fees. The fees are
accrued daily and paid monthly at annual rates based upon the
average daily net assets of the shares as follows:


                                       Account
                                     Maintenance    Distribution
                                         Fee            Fee

Class B                                 0.25%          0.25%
Class C                                 0.25%          0.35%
Class D                                 0.10%            --

<PAGE>
Pursuant to a sub-agreement with the Distributor, Merrill Lynch,
Pierce, Fenner & Smith Inc. ("MLPF&S"), a subsidiary of ML & Co.,
also provides account maintenance and distribution services to the
Fund. The ongoing account maintenance fee compensates the
Distributor and MLPF&S for providing account maintenance services to
Class B, Class C and Class D shareholders. The ongoing distribution
fee compensates the Distributor and MLPF&S for providing shareholder
and distribution-related services to Class B and Class C
shareholders.

For the six months ended January 31, 1996, MLFD earned underwriting
discounts and MLPF&S earned dealer concessions on sales of the
Fund's Class A and Class D Shares as follows:


                                         MLFD         MLPF&S

Class A                                  $ 61         $  287
Class D                                  $952         $4,300


For the six months ended January 31, 1996, MLPF&S received
contingent deferred sales charges of $23,140 and $200 relating to
transactions in Class B and Class C Shares, respectively.

Merrill Lynch Financial Data Services, Inc. ("MLFDS"), a wholly-
owned subsidiary of ML & Co., is the Fund's transfer agent.

Accounting services are provided to the Fund by FAM at cost.

Certain officers and/or trustees of the Fund are officers and/or
directors of FAM, PSI, MLPF&S, MLFDS, MLFD, and/or ML & Co.


NOTES TO FINANCIAL STATEMENTS (concluded)


3. Investments:
Purchases and sales of investments, excluding short-term securities,
for the six months ended January 31, 1996 were $12,485,209 and
$9,490,828, respectively.

Net realized and unrealized gains (losses) as of January 31, 1996
were as follows:


                                    Realized      Unrealized
                                  Gains (Losses)    Gains

Long-term investments                $ 91,936    $ 2,072,700
Financial futures contracts          (132,124)            --
                                     --------    -----------
Total                                $(40,188)   $ 2,072,700
                                     ========    ===========

<PAGE>
As of January 31, 1996, net unrealized appreciation for Federal
income tax purposes aggregated $2,072,700, of which $2,073,278
related to appreciated securities and $578 related to depreciated
securities. The aggregate cost of investments at January 31, 1996
for Federal income tax purposes was $28,437,116.

4. Beneficial Interest Transactions:
Net increase in net assets derived from beneficial interest
transactions was $1,296,540 and $2,801,169 for the six months ended
January 31, 1996 and for the year ended July 31, 1995, respectively.

Transactions in shares of beneficial interest for each class were as
follows:


Class A Shares for the Six Months                   Dollar
Ended January 31, 1996                Shares        Amount

Shares sold                           137,590    $ 1,313,816
Shares issued to shareholders
in reinvestment of dividends            8,947         85,529
                                  -----------    -----------
Total issued                          146,537      1,399,345
Shares redeemed                      (207,769)    (1,983,491)
                                  -----------    -----------
Net decrease                          (61,232)   $  (584,146)
                                  ===========    ===========



Class A Shares for the Year                         Dollar
Ended July 31, 1995                   Shares        Amount

Shares sold                           845,320    $ 7,350,840
Shares issued to shareholders
in reinvestment of dividends           17,353        159,391
                                  -----------    -----------
Total issued                          862,673      7,510,231
Shares redeemed                      (958,997)    (8,589,491)
                                  -----------    -----------
Net decrease                          (96,324)   $(1,079,260)
                                  ===========    ===========



Class B Shares for the Six Months                   Dollar
Ended January 31, 1996                Shares        Amount
<PAGE>
Shares sold                           315,138    $ 3,018,344
Shares issued to shareholders
in reinvestment of dividends           17,276        165,298
                                  -----------    -----------
Total issued                          332,414      3,183,642
Shares redeemed                      (222,111)    (2,127,641)
Automatic conversion of shares         (1,211)       (11,493)
                                  -----------    -----------
Net increase                          109,092    $ 1,044,508
                                  ===========    ===========



Class B Shares for the Year                         Dollar
Ended July 31, 1995                   Shares        Amount

Shares sold                           590,823    $ 5,418,198
Shares issued to shareholders
in reinvestment of dividends           30,471        279,150
                                  -----------    -----------
Total issued                          621,294      5,697,348
Shares redeemed                      (349,817)    (3,164,237)
                                  -----------    -----------
Net increase                          271,477    $ 2,533,111
                                  ===========    ===========
                        



Class C Shares for the Six Months                   Dollar
Ended January 31, 1996                Shares        Amount

Shares sold                            37,155    $   350,941
Shares issued to shareholders
in reinvestment of dividends              587          5,639
                                  -----------    -----------
Total issued                           37,742        356,580
Shares redeemed                        (5,090)       (49,877)
                                  -----------    -----------
Net increase                           32,652    $   306,703
                                  ===========    ===========



Class C Shares for the Period
October 21, 1994++ to                               Dollar
July 31, 1995                         Shares        Amount
<PAGE>
Shares sold                            17,718    $   165,714
Shares issued to shareholders
in reinvestment of dividends              121          1,130
                                  -----------    -----------
Total issued                           17,839        166,844
Shares redeemed                          (581)        (5,534)
                                  -----------    -----------
Net increase                           17,258    $   161,310
                                  ===========    ===========

[FN]
++Commencement of Operations.



Class D Shares for the Six Months                   Dollar
Ended January 31, 1996                Shares        Amount

Shares sold                            60,076    $   579,673
Automatic conversion of shares          1,212         11,493
Shares issued to shareholders
in reinvestment of dividends            1,902         18,204
                                  -----------    -----------
Total issued                           63,190        609,370
Shares redeemed                        (8,256)       (79,895)
                                  -----------    -----------
Net increase                           54,934    $   529,475
                                  ===========    ===========



Class D Shares for the Period
October 21, 1994++ to                               Dollar
July 31, 1995                         Shares        Amount

Shares sold                           160,346    $ 1,421,717
Shares issued to shareholders
in reinvestment of dividends            1,729         16,078
                                  -----------    -----------
Total issued                          162,075      1,437,795
Shares redeemed                       (27,599)      (251,787)
                                  -----------    -----------
Net increase                          134,476    $ 1,186,008
                                  ===========    ===========

[FN]
++Commencement of Operations.

5. Capital Loss Carryforward:
At July 31, 1995, the Fund had a net capital loss carryforward of
approximately $1,707,000, all of which expires in 2003. This amount
will be available to offset like amounts of any future taxable
gains.
<PAGE>





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