December 2,1999
Securities and Exchange Commission
450 Fifth Street, N.W.
Judiciary Plaza
Washington, D.C. 20549
Attention: Division of Investment Management
Re: Merrill Lynch Colorado Municipal Bond
Fund of Merrill Lynch Multi-State
Municipal Series Trust Post-Effective
Amendment No. 8 to the Registration
Statement on Form N-1A(Securities Act
File No. 33-50051 Investment Company
Act File No. 811-4375)
Ladies and Gentlemen:
Pursuant to Rule 497(j) under the Securities
Act of 1933, as amended (the "1933 Act"),
Merrill Lynch Colorado Municipal Bond Fund of
Merrill Lynch Multi-State Municipal Series Trust
(the "Trust") hereby certifies that:
(1) the form of prospectus and statement of additional
information that would have been filed pursuant
to Rule 497 (c) under the 1933 Act would not have
differed from that contained in Post-Effective
Amendment No. 8 to the Trust's Registration
Statement on Form N-1A, constituting the most
recent amendment to the Trust's Registration
Statement on Form N-1A; and
(2) the text of Post-Effective Amendment No. 8 to
the Trust's Registration Statement on Form N-1A
was filed electronically with the Securities and
Exchange Commission on November 24,1999.
Very truly yours,
Merrill Lynch Colorado Municipal
Bond Fund of Merrill Lynch Multi-
State Municipal Series Trust
By: Alice A. Pellegrino /s/
_________________________
Alice A. Pellegrino
Secretary
