KEMPER DEFINED FUNDS SERIES 45
497J, 1995-07-10
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                         KEMPER UNIT INVESTMENT TRUSTS
                             77 WEST WACKER DRIVE
                            CHICAGO, ILLINOIS 60601

                                 July 10, 1995


Securities and Exchange Commission
450 Fifth Street, N.W.
Washington D.C. 20549-1004

Attn: Filing Desk, Stop 1-4


      Re:               Kemper Defined Funds Series 45
                     (File No. 33-60401) (CIK No. 910913)
                     ------------------------------------

Gentlemen:

      In accordance with the provisions of Rule 497(j) of Regulation C under the
Securities Act of 1933 (the "Securities Act") this letter serves to certify that
the most recent amendment to the registration statement on Form S-6 for the
above captioned Trust does not differ from that which would have been filed
pursuant to Rule 497(b) of the Securities Act. Amendment No. 1, which was the
most recent Amendment to the Registration Statement, filed electronically with
the Commission on July 7, 1995.

                                       Very truly yours,



                                       KEMPER UNIT INVESTMENT TRUSTS


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