CADUS PHARMACEUTICAL CORP
S-8 POS, 1997-12-23
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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<PAGE>
                                                      Registration No. 333-21871

================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                              -------------------
                                 POST-EFFECTIVE
                               AMENDMENT NO. 2 TO
                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                        CADUS PHARMACEUTICAL CORPORATION
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)

                                    Delaware
         --------------------------------------------------------------
         (State or other jurisdiction of incorporation or organization)

                                   13-3660391
                      ------------------------------------
                      (I.R.S. Employer Identification No.)

           777 Old Saw Mill River Road, Tarrytown, New York 10591-6705
           -----------------------------------------------------------
                    (Address of Principal Executive Offices)

             Cadus Pharmaceutical Corporation 1993 Stock Option Plan
              Cadus Pharmaceutical Corporation 1996 Incentive Plan
              Written Compensation Contracts with Certain Employees
           Written Compensation Contracts with Non-Employee Directors
             Written Compensation Contracts with Certain Consultants
           -----------------------------------------------------------
                            (Full Title of the Plan)

                                 Jeremy M. Levin
                        Cadus Pharmaceutical Corporation
                           777 Old Saw Mill River Road
                         Tarrytown, New York 10591-6705
                     ---------------------------------------
                     (Name and Address of Agent For Service)

                                 (914) 345-3344
          -------------------------------------------------------------
          (Telephone Number, Including Area Code, of Agent For Service)

                        Copy to: Salomon R. Sassoon, Esq.
                     Morrison Cohen Singer & Weinstein, LLP
                              750 Lexington Avenue
                            New York, New York 10022
                                 (212) 735-8600

================================================================================

<PAGE>

                  Cadus Pharmaceutical Corporation (the "Company") hereby amends
the Registration Statement on Form S-8 (the "Registration Statement") filed with
the Securities and Exchange Commission (the "SEC") on February 14, 1997, File
No. 333-21871, as amended by Post-Effective Amendment No. 1 thereto, filed with
the SEC on March 10, 1997, in order to register an additional 1,000,000 shares
of Common Stock that are issuable upon the exercise of options and stock
appreciation rights which may be granted under the Company's 1996 Incentive Plan
(the "Plan"), which additional 1,000,000 shares of Common Stock were added
pursuant to Amendment No. 2 to the Plan adopted by the Board of Directors of the
Company on December 11, 1997. The contents of the Registration Statement filed
with the SEC by the Company on February 14, 1997, Post-Effective Amendment No. 1
to the Registration Statement filed with the SEC on March 10, 1997, and all
documents referenced therein are incorporated herein by reference.

<PAGE>

                         CALCULATION OF REGISTRATION FEE

<TABLE>
<CAPTION>
==================================================================================================================================
      Title of Securities            Amount to be           Proposed Maximum             Proposed Maximum            Amount of
       to be Registered               Registered        Offering Price Per Share     Aggregate Offering Price     Registration Fee
==================================================================================================================================
<S>                                  <C>                <C>                          <C>                          <C>      
Common Stock, par value $0.01
per share, issuable upon exercise
of options and stock appreciation
rights which may be granted           Additional
under 1996 Incentive Plan              1,000,000               $8.3125(1)                 $8,312,500.00               $2,452.19
==================================================================================================================================

            Total Registration Fee   . . . . . . . . . . . . . . . . . . . . . . . . . .  $2,452.19
==================================================================================================================================
</TABLE>

- -------------------------

(1)      Estimated in accordance with Rules 457(c) and (h) solely for the
         purpose of calculating the registration fee and based upon the average
         of the high and low trade prices of Common Stock of Cadus
         Pharmaceutical Corporation as reported by the NASDAQ Stock Market on
         December 18, 1997.

                                        1

<PAGE>


                                   SIGNATURES


                  Pursuant to the requirements of the Securities Act of 1933, as
amended, the registrant certifies that it has reasonable grounds to believe that
it meets all of the requirements for filing on Form S-8 and has duly caused this
Post-Effective Amendment No. 2 to the Registration Statement to be signed on its
behalf by the undersigned, thereunto duly authorized, in the City of Tarrytown,
State of New York, on this 17th day of December, 1997.

                                    CADUS PHARMACEUTICAL CORPORATION

                                    By:  /s/ Jeremy M. Levin
                                         -------------------------------------
                                         Jeremy M. Levin
                                         President and Chief Executive Officer

                  Pursuant to the requirements of the Securities Act of 1933, as
amended, this Post-Effective Amendment No. 2 to the Registration Statement has
been signed below by the following persons in the capacities and on the dates
indicated:

<TABLE>
<CAPTION>
         Signature                                            Title                                           Date
         ---------                                            -----                                           ----
<S>                                              <C>                                                    <C> 
/s/ Jeremy M. Levin                              President and Chief Executive Officer                  December 17, 1997
- ------------------------------------             (Principal Executive Officer) and
     Jeremy M. Levin                             Chairman of the Board of Directors

/s/ James S. Rielly                              Director of Finance, Controller,                       December 17, 1997
- ------------------------------------             Treasurer and Secretary (Principal
     James S. Rielly                             Financial and Accounting Officer)

                                                 Director                                               December 17, 1997
- ------------------------------------
     Carl C. Icahn

                                                 Director                                               December 17, 1997
- ------------------------------------
     Theodore Altman

/s/ Harold First                                 Director                                               December 17, 1997
- ------------------------------------
     Harold First

            *                                    Director                                               December 17, 1997
- ------------------------------------
     Peter Liebert


            *                                    Director                                               December 17, 1997
- ------------------------------------
     Robert Mitchell

            *                                    Director                                               December 17, 1997
- ------------------------------------
     Lawrence Muschek

                                                 Director                                               December 17, 1997
- ------------------------------------
     Mark H. Rachesky

                                                 Director                                               December 17, 1997
- ------------------------------------
     Leon E. Rosenberg

            *                                    Director                                               December 17, 1997
- ------------------------------------
     Nicole Vitullo

                                                 Director                                               December 17, 1997
- ------------------------------------
     Samuel D. Waksal

            *                                    Director                                               December 17, 1997
- ------------------------------------
     Jack G. Wasserman


*By: /s/ Jeremy M. Levin
     -------------------------------
     Jeremy M. Levin,
     Attorney-in-Fact
</TABLE>

                                        2

<PAGE>

                                  EXHIBIT INDEX

No.     Description
- ---     -----------

4.      Amendment No. 2 to Cadus Pharmaceutical Corporation 1996 Incentive Plan.

5.      Opinion of Morrison Cohen Singer & Weinstein, LLP, as to the validity
        of the securities being registered.

23.1    Consent of KPMG Peat Marwick LLP.

23.2    Consent of Morrison Cohen Singer & Weinstein, LLP (contained in its
        Opinion filed as Exhibit 5).




<PAGE>

                                    EXHIBIT 4

                                 AMENDMENT NO. 2
                                       TO
                        CADUS PHARMACEUTICAL CORPORATION
                               1996 INCENTIVE PLAN



         This Amendment No. 2 to the Cadus Pharmaceutical Corporation 1996
Incentive Plan (the "Plan") was adopted by the Board of Directors of Cadus
Pharmaceutical Corporation on December 11, 1997.

                  The first sentence of Section 2.2 of the Plan is hereby
amended to read as follows:

                  "2.2 Maximum Shares Available. The maximum aggregate number of
shares of Common Stock available for award under the Plan is 1,833,334, subject
to adjustment pursuant to Article 12 hereof."




<PAGE>

                                    EXHIBIT 5

                               OPINION OF COUNSEL

             [Letterhead of Morrison Cohen Singer & Weinstein, LLP]

                                 (212) 735-8600


                                    December 17, 1997

Cadus Pharmaceutical Corporation
777 Old Saw Mill River Road
Tarrytown, New York 10591

          Re:     Cadus Pharmaceutical Corporation
                  Post-Effective Amendment No. 2 to 
                  Registration Statement on Form S-8

Gentlemen:

          We have acted as counsel to Cadus Pharmaceutical Corporation, a
Delaware corporation (the "Company"), in connection with the preparation of
Post-Effective Amendment No. 2 to the Registration Statement on Form S-8
("Amendment No. 2") being filed by the Company with the Securities and Exchange
Commission under the Securities Act of 1933, as amended, covering an aggregate
of an additional 1,000,000 shares (the "Shares") of common stock of the Company,
$.01 par value per share (the "Common Stock"), issuable upon the exercise of
stock options and stock appreciation rights which may be granted under the
Company's 1996 Incentive Plan (the "Plan").

          In so acting, we have examined copies of such records of the Company
and such other certificates and documents as we have deemed relevant and
necessary for the opinion hereinafter set forth. In such examination, we have
assumed the genuineness of all signatures, the authenticity of all documents
submitted to us as originals and the conformity to authentic originals of all
documents submitted to us as certified or reproduced copies. We have also
assumed the legal capacities of all persons executing such documents and the
truth and correctness of any representations or warranties contained therein. As
to various questions of fact material to such opinion, we have relied upon
certificates of officers of the Company.

          Based upon and subject to the foregoing, we are of the opinion that
the Shares issuable upon exercise of the stock options and stock appreciation
rights which may be granted under the Plan, when paid for and issued in
accordance with the terms of such stock options and stock appreciation rights,
will be validly issued and fully paid and nonassessable.

          We hereby consent to your filing copies of this opinion as an exhibit
to Amendment No. 2.

                                    Very truly yours,

                                    /s/ Morrison Cohen Singer & Weinstein, LLP

                                    MORRISON COHEN SINGER & WEINSTEIN, LLP



<PAGE>



                        Independent Auditors' Consent
                        -----------------------------


The Board of Directors
Cadus Pharmaceutical Corporation:

We consent to the use of our report incorporated herein by reference.


White Plains, New York
December 22, 1997                      /s/ KPMG Peat Marwick LLP







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