PALATIN TECHNOLOGIES INC
10KSB, 1997-09-26
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                     U.S. SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                      ------------------------------------


                                   FORM 10-KSB

|X|      ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
         ACT OF 1934 FOR THE FISCAL YEAR ENDED JUNE 30, 1997

                                       or

|_|      TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
         EXCHANGE ACT OF 1934

                         Commission file number 0-22686

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                           PALATIN TECHNOLOGIES, INC.
                 (Name of small business issuer in its charter)

               Delaware                               95-4078884
   (State or other jurisdiction of        (I.R.S. Employer Identification No.)
    incorporation or organization) 
 
    214 Carnegie Center - Suite 100
        Princeton, New Jersey                           08540
(Address of principal executive offices)              (Zip Code)

                    Issuer's telephone number: (609) 520-1911

       Securities registered under Section 12(b) of the Exchange Act: None

         Securities registered under Section 12(g) of the Exchange Act:

                     Common Stock, par value $.01 per share
                                (Title of class)

Check  whether the issuer (1) filed all reports  required to be filed by Section
13 or 15(d) of the  Exchange  Act during the past 12 months (or for such shorter
period that the registrant was required to file such reports),  and (2) has been
subject to such filing requirements for the past 90 days. Yes X   No __

Check if there is no disclosure of delinquent  filers in response to Item 405 of
Regulation S-B contained in this form, and no disclosure  will be contained,  to
the best of the  registrant's  knowledge,  in  definitive  proxy or  information
statements  incorporated  by reference in Part III of this Form 10-KSB or by any
amendment to this Form 10-KSB. |_|

The issuer's revenues for the period ended June 30, 1997 were $722,357.

The aggregate  market value of the voting and  non-voting  common equity held by
non-affiliates computed by reference to the price at which the common equity was
sold, or the average bid and asked price of such common equity,  as of September
23, 1997, was $16,903,608.

As of September 23, 1997, 3,041,111 shares of the registrant's common stock, par
value $.01 per share, were outstanding.

Documents incorporated by reference: None.

Transitional Small Business Disclosure Format:  Yes __    No X

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<TABLE>
<CAPTION>

                                                     Table of Contents
<S>               <C>                                                                                                 <C>

                                                          PART I                                                      Page

Item  1.          Description of Business..........................................................................      1

Item  2.          Description of Property............................................................................   25

Item  3.          Legal Proceedings.................................................................................    25

Item  4.          Submission of Matters to a Vote of Security Holders...............................................    26


                                                          PART II

Item  5.          Market for Common Equity and Related Stockholder Matters..........................................    27

Item  6.          Management's Discussion and Analysis
                  of Financial Condition and Results of Operations..................................................    30

Item  7.          Financial Statements...............................................................................   33

Item  8.          Changes In and Disagreements with Accountants
                  on Accounting and Financial Disclosure.............................................................   34


                                                         PART III

Item  9.          Directors, Executive Officers, Promoters and Control Persons;
                  Compliance with Section 16(a) of the Exchange Act..................................................   34

Item 10.          Executive Compensation.............................................................................   37

Item 11.          Security Ownership of Certain Beneficial Owners and Management.....................................   42

Item 12.          Certain Relationships and Related Transactions.....................................................   48

Item 13.          Exhibits and Reports on Form 8-K...................................................................   49

Signatures        ...................................................................................................   54

</TABLE>


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         Unless  the  context  otherwise  requires,(i)  all  references  to  the
"Company" or "Palatin" include Palatin  Technologies,  Inc. and its wholly-owned
subsidiary, RhoMed Incorporated ("RhoMed"), (ii) all references to the Company's
activities, results of operations and financial condition prior to June 25, 1996
relate to RhoMed and (iii) all  references to the Company's  common stock,  $.01
par value (the "Common  Stock") are to the  Company's  Common Stock after giving
effect to the 1-for-10  reverse  split of the Common Stock  effected on July 19,
1996 and the 1-for-4  reverse split of the Common Stock effected on September 5,
1997.  See  Item 1 and  Item 4 in  this  Annual  Report  on  Form  10-KSB  (this
"Report").

         Certain   statements   in  this  Report   constitute   "forward-looking
statements" within the meaning of the Private  Securities  Litigation Reform Act
of 1995.  Such  forward-looking  statements  involve  known and  unknown  risks,
uncertainties and other factors which may cause the actual results,  performance
or achievements of the Company, or industry results, to be materially  different
from any future results,  performance,  or achievements  expressed or implied by
such  forward-looking  statements.  Such  factors  include,  among  others,  the
following:  delays in product  development;  problems  or delays  with  clinical
trials;  failure to receive or delays in receiving regulatory approval;  lack of
enforceability of patents and proprietary rights; lack of reimbursement; general
economic  and  business   conditions;   industry   capacity;   industry  trends;
competition;  material costs and  availability;  changes in business strategy or
development plans; quality of management;  availability, terms and deployment of
capital; business abilities and judgment of personnel; availability of qualified
personnel;  changes in, or the failure to comply with,  government  regulations;
and  other  factors  referenced  in this  Report.  When  used  in  this  Report,
statements  that are not  statements  of  historical  fact may be  deemed  to be
forward-looking   statements.   Without   limiting  the  foregoing,   the  words
"anticipates,"   "plans,"  "intends,"  "expects"  and  similar  expressions  are
intended to identify such forward-looking statements.  Readers are cautioned not
to place undue reliance on these forward-looking statements, which speak only as
of the date hereof. The Company undertakes no obligation to publicly release the
result of any revisions to these forward-looking  statements that may be made to
reflect  events  or  circumstances  after  the date  hereof  or to  reflect  the
occurrence of unanticipated events.



                                     PART I

ITEM 1.           DESCRIPTION OF BUSINESS.

GENERAL

         The Company is a development-stage  biopharmaceutical company dedicated
to developing  and  commercializing  products and  technologies  for  diagnostic
imaging,   cancer  therapy  and  ethical  drug  development  utilizing  peptide,
monoclonal   antibody   and   radiopharmaceutical   technologies.   The  Company
concentrates its activities in two technology  areas,  each of which the Company
believes  may  be  used  to  develop  products  with  potential  diagnostic  and
therapeutic   applications.   These  technologies   involve  the  Company's  (i)
patent-pending Metal Ion-induced  Distinctive Array of Structures  ("MIDAS(TM)")
metallopeptide   technology   ("MIDAS   technology")   and  (ii)   patented  and
patent-pending direct radiolabeling technology.

         The Company  believes that the MIDAS  technology  represents a platform
technology which may enable the design and synthesis of novel peptide analogs or
mimics.  Further, the Company believes that its MIDAS technology may provide the
Company with the flexibility to generate its own  pharmaceutical  products,  and
the  ability  to  target  and  complement   existing   product   portfolios  and
technological bases of

                                     Page 1

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other  companies.  The  Company  intends  to seek to  enter  into  collaborative
arrangements  to assist in development,  manufacturing  and marketing of certain
proposed products utilizing the MIDAS technology. The Company has entered into a
license  option  agreement  as to  certain  proposed  products  based  on  MIDAS
technology. See "MIDAS Technology" in this Item 1.

         The Company is  developing  two  proposed  products  incorporating  its
direct radiolabeling technology, (i) LeuTech(TM),  an infection and inflammation
imaging product,  and (ii) PT-5, a radiotherapeutic  peptide somatostatin analog
for cancer therapy. The Company is devoting substantial efforts and resources to
the  development  of  LeuTech,  which  the  Company  believes  will be its first
proposed  product  to  enter  Company-sponsored  clinical  trials.  The  Company
anticipates  seeking one or more marketing partners for LeuTech prior to product
approval. See "Direct Radiolabeling Technology" in this Item 1.

         The  Company  is at an  early  stage  of  development  and  has not yet
completed the  development of any products based on either its MIDAS  technology
or its direct radiolabeling technology.  Accordingly,  the Company has not begun
to market or generate revenues from the  commercialization of any such products.
It will be a number  of  years,  if ever,  before  the  Company  will  recognize
significant revenues from product sales or royalties. The Company's technologies
and products  under  development  will require  significant  time-consuming  and
costly research, development, pre-clinical studies, clinical testing, regulatory
approval and significant additional investment prior to their commercialization,
which may never occur. There can be no assurance that the Company's research and
development  programs  will be  successful,  that its products  will exhibit the
expected  biological results in humans, will prove to be safe and efficacious in
clinical  trials or will obtain the  required  regulatory  approvals or that the
Company or its  collaborators  will be successful in obtaining market acceptance
of any of the  Company's  products.  There can be no assurance  that the Company
will be  successful  in  entering  into  strategic  alliances  or  collaborative
arrangements  on  commercially  reasonable  terms,  if  at  all,  or  that  such
arrangements will be successful, or that the parties with which the Company will
establish  arrangements will perform their obligations under such  arrangements.
The Company or its collaborators  may encounter  problems and delays relating to
research and development,  regulatory approval, manufacturing and marketing. The
failure by the Company to address  successfully  such  problems and delays would
have a material adverse effect on the Company. In addition,  no assurance can be
given that  proprietary  rights of third  parties  will not preclude the Company
from  marketing  its  proposed  products or that third  parties  will not market
superior or equivalent products.

MIDAS TECHNOLOGY

         Role and Function of Peptides.  Peptides,  short chains of amino acids,
play important  roles in regulating a variety of biological  functions.  Natural
peptides  function by  conforming  or bending to fit specific  molecules on cell
surfaces, called receptors,  thereby signaling the cell to initiate a biological
activity.  Some important  biological functions that are affected in this manner
include overall growth and behavior,  inflammatory  responses,  immune responses
and wound healing.

         In order to effectively regulate cell signaling, a peptide must bind to
its target receptor with high affinity. The affinity of a peptide for its target
receptor is highly  dependent on its  three-dimensional  shape or  conformation.
Many  naturally  occurring  peptides  are  flexible  and can  take  on  multiple
conformations,  allowing  them to  interact  with  more  than  one  type of cell
receptor,  and to control multiple functions within the body. However, when such
peptides are used as drugs, this multiple reactivity is a disadvantage as it may
lead to side effects. The ability to construct high-affinity,  receptor-specific
peptides  offers a significant  opportunity to develop potent  receptor-specific
drugs.

                                     Page 2

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         Introduction  to  MIDAS  Technology.  The  Company  believes  that  its
patent-pending  MIDAS  technology  can be used to rationally  design and produce
receptor-specific drugs. Using MIDAS, highly stable metallopeptide complexes are
formed,  in which the metal ion locks or constrains  the peptide into a specific
conformation. By designing MIDAS peptides to mimic the conformation required for
a specific receptor,  a stable,  receptor-specific  drug, with high affinity and
enhanced biological activity, can be made.  Radiopharmaceutical  products, which
may be diagnostic or therapeutic,  may be developed using radioactive metal ions
in MIDAS peptides.  Non-radioactive metal ions may be used in the development of
biopharmaceutical MIDAS peptides.

         The  Company is  engaged in  research  and  development  on a number of
product  opportunities for its MIDAS  technology,  including use as a thrombosis
imaging agent,  an infection  imaging agent and an  immunostimulatory  agent. No
prediction can be made,  however, as to when or whether the areas in which there
are  ongoing  MIDAS   technology   research   projects  will  yield   scientific
discoveries, or whether such research projects will lead to commercial products

         Research  Projects.   Certain   pre-clinical  work  on  development  of
MIDAS-based  products has been  supported,  in part, by three Phase I grants for
$100,000,  $93,948  and $94,970  under the Small  Business  Innovative  Research
("SBIR") program awarded to the Company by the National  Institutes of Health of
the  Department of Health and Human  Services  ("NIH").  The Company  intends to
apply for Phase II SBIR grants,  each in an amount of up to  $750,000,  although
there can be no assurance that any Phase II grant will be awarded.

         Other  Potential  Opportunities.  The Company is evaluating a number of
product  opportunities  for  its  MIDAS  technology,   and  believes  that  this
technology may have medical applications in a variety of areas, including immune
disorders,  cancers and  cardiology.  The Company intends to expand research and
development  of  MIDAS  technology   applications  primarily  through  strategic
alliances  with  other  entities.  No  assurances  can  be  made  regarding  the
establishment or the timing of such alliances, and the failure to establish such
alliances on a timely basis could limit the  Company's  ability to develop MIDAS
technology and could have a material adverse effect on the Company.  The Company
expects  to  devote  resources  to  expand  research  and  development  of MIDAS
technology to the extent funding is available.

         Option  Agreement with Nihon. The Company entered into a License Option
Agreement (the "Option  Agreement") with Nihon  Medi-Physics Ltd.  ("Nihon"),  a
Japanese developer and manufacturer of  radiopharmaceutical  drugs,  pursuant to
which the Company  received an initial  payment of  $1,000,000  before  Japanese
withholding taxes of $100,000. Pursuant to the Option Agreement (i) Nihon has an
option to exclusively  license  certain  jointly  developed  radiopharmaceutical
diagnostic  products based on the Company's MIDAS  technology and (ii) Nihon can
maintain its option by making  certain  milestone  payments based on progress in
product  development.  Nihon  may  exercise  its  right to  negotiate  a license
agreement  at any time upon  notice  and  payment  of  additional  monies to the
Company.  There can be no  assurance  that future  payments  provided for in the
Option Agreement will be made, that the Company and Nihon will ever enter into a
definitive  license agreement,  or that a definitive  strategic alliance between
the Company and Nihon will result in the development or commercialization of any
product.  In the event  that  Nihon  gives  notice of its right to  negotiate  a
license  agreement,  and the  parties  cannot  agree on  terms  of such  license
agreement,  the Company may be required to repay  $550,000 to Nihon.  Failure to
enter into a definitive  license  agreement,  or being required to repay certain
monies to Nihon, may have a material adverse effect on the Company. See Item 6.

                                     Page 3

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DIRECT RADIOLABELING TECHNOLOGY

         The Company has developed and patented  radiolabeling  technologies for
the  direct  radiolabeling  of  antibodies,  peptides  and other  proteins  with
diagnostic and therapeutic radioisotopes.

         LeuTech Diagnostic  Imaging Product.  LeuTech, a proposed product under
development  that  utilizes  direct  radiolabeling  technology,  is a murine (or
mouse)  monoclonal  antibody-based  product  designed  to be  labeled  with  the
diagnostic  radioisotope  technetium-99m.  When  labeled  with   technetium-99m,
LeuTech is intended to be used for diagnosis of  infections,  occult  abscesses,
sites of inflammatory disease and other conditions involving high concentrations
of white blood cells.

         The Company  believes that LeuTech can be used for the rapid  diagnosis
of a variety of difficult to diagnose  infections and occult  abscesses.  Occult
abscesses are hidden infections that are generally characterized as being highly
localized.  Examples  of typical  occult  abscesses  include  infections  of the
intra-abdominal  area,  such as  intestinal,  spleen,  liver  or  urinary  tract
abscesses,  as well as  bone,  prosthetic  and  other  abscesses.  In a  typical
abscess,  as in most infections,  large numbers of white blood cells congre gate
at the site of the infection.  Thus, if the location of  concentrations of white
blood cells is known,  the site of the infection is also known. It is crucial in
the  diagnosis  and  treatment  of occult  abscesses  that the  location  of the
infection be  determined,  as location  will  frequently  determine  the type of
therapy which is appropriate.

         The most specific  procedure  currently  available for nuclear medicine
imaging  of sites of  infection  involves  removal  of blood  from the  patient,
isolating white blood cells from the patient's  blood,  radiolabeling  the white
blood  cells and  injecting  the  radiolabeled  white  blood cells back into the
patient.  The  radiolabeled  white blood cells then  localize at the site of the
infection, and can be detected using nuclear medicine diagnostic equipment. This
procedure is expensive,  involves risks to patients and  technicians  associated
with blood handling, is difficult to perform and generally takes at least twelve
hours.

         LeuTech has been  formulated as a  lyophilized,  or  freeze-dried,  kit
containing  the modified  antibody and reagents  required for the  radiolabeling
process.  Prior  to use,  LeuTech  will be  labeled  with   technetium-99m  by a
radiopharmacy  or  by a  hospital's  nuclear  medicine  department.  LeuTech  is
designed to bind, in the body, to white blood cells already  present at the site
of the infection or circulating in the blood stream. Therefore, LeuTech does not
require handling or processing of patient blood.

         Preliminary    clinical   trials   have   been   conducted   under   an
Investigational   New  Drug   Application   ("IND")  held  in  the  name  of  an
investigator,  using  purified  antibody or kits provided by the Company.  Forty
patient  studies  have  been  completed  at  UCLA/Harbor  Medical  Center in Los
Angeles,  with images  obtained in a variety of  diseases,  including  acute and
suspected appendicitis,  pulmonary infections and other abdominal infections. In
seven cases satisfactory images were not obtained,  due primarily to labeling or
product  formulation  failures  with  early  kit  formulations.  In some  cases,
diagnostic  images have been obtained within five minutes of  administration  of
LeuTech,  and in all  cases  in  which a  definitive  diagnosis  could  be made,
diagnostic images have been obtained within 90 minutes. An additional  seventeen
patient studies were completed in Germany at the University of Gottingen,  using
kits manufactured by a third party to the Company's specifications,  with images
obtained in osteomyelitis and soft tissue infections.

         The Company has entered into an exclusive  license  agreement  with The
Wistar Institute of Anatomy and Biology ("Wistar Institute") to use the antibody
and cell line used for LeuTech for a defined  field of use.  Failure to meet the
performance  criteria  for any reason or any other  event of  default  under the
license  agreement  leading to termination of the license  agreement with Wistar
Institute would have a material

                                     Page 4

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adverse  effect on the  Company.  While the Company has  negotiated  a long-term
contractual  arrangement for the manufacture of the purified antibody  necessary
for LeuTech,  there can be no  assurance  that such  contractor  will be able to
successfully  manufacture  purified  antibody for LeuTech on a sustained  basis,
that such contractor will remain in the contract  manufacturing business for the
time  required by the  Company,  or that the Company  will be able to enter into
such  contractual  arrangements  as to other  steps and  components  required to
manufacture  LeuTech. To date, the Company has only manufactured LeuTech in lots
preparatory to initiating  clinical  trial use, and has not  determined  whether
commercial  quantities  of LeuTech in  conformity  with these  standards  can be
manufactured on a sustained basis at an acceptable  cost. Such  manufacture must
be done under good manufacturing  practices ("GMP")  requirements  prescribed by
the United  States  Food and Drug  Administration  ("FDA")  and other  agencies.
Certain steps in the manufacture of LeuTech,  including contract  manufacture of
purified antibody, vialing and lyophilization, have been done under GMP.

         The Company  intends to file an IND  application on LeuTech to initiate
clinical trials on one or more selected  indications in the second half of 1997,
and to complete Phase III clinical  trials and file  regulatory  applications to
market with the FDA in the second half of 1998.  There can be no assurance  that
the Company's LeuTech development program will be successful,  that the FDA will
permit the Company's planned clinical trials to proceed, that LeuTech will prove
to be safe and efficacious in clinical trials,  that LeuTech can be manufactured
in commercially required quantities on a sustained basis at an acceptable price,
that LeuTech will obtain the required  regulatory  approvals or that the Company
or its  collaborators  will be  successful  in obtaining  market  acceptance  of
LeuTech.  The Company or its  collaborators  may  encounter  problems and delays
relating to research and development,  regulatory  approval,  manufacturing  and
marketing of LeuTech.

         PT-5 Cancer Therapeutic Product. PT-5 is a rhenium-labeled somatostatin
peptide analog being developed by the Company which is intended to treat cancers
by  regional  delivery  of  tumor  cell-targeted  radiotherapy.  PT-5  binds  to
somatostatin  receptors.  Somatostatin is a natural peptide hormone  involved in
the regulation of cell growth and  differentiation,  and somatostatin  receptors
are over-expressed on a wide variety of cancers. PT-5 is intended to target such
cancers and deliver a therapeutic  dose of  rhenium-188,  a  radioisotope  which
emits high energy beta radiation, to the cancer.

         The  Company  has  developed  a  reproducible,  easy to use,  and  high
efficiency direct  radiolabeling  method for PT-5; developed a lyophilized final
product formulation; conducted biodistribution studies of PT-5 in normal animals
using several  different  routes of  administration,  including  intravenous and
intra-cavity  administration;  conducted  biodistribution  studies  of  PT-5  in
tumor-bearing  animals;  and demonstrated  that PT-5 has a specific  therapeutic
effect in animal models of three  different  human tumors -- lung,  prostate and
breast cancers.

         The Company  believes PT-5 may have  applications for local or regional
administration to any  compartmentalized  cancer which is  somatostatin-receptor
positive.  The cancer must be  compartmentalized  in order for local or regional
administration  to work and must express  somatostatin  receptors in  reasonably
high levels in order to obtain the  targeting  benefits of PT-5.  Expression  of
somatostatin receptors varies by type of cancer.  However, until clinical trials
are completed,  specific  clinical utility and  applications,  if any, cannot be
determined.

         The Company is working with  researchers  at the  University of Bonn in
Germany to initiate clinical trials of patients with bronchial cancer metastatic
to the pleural cavity.  PT-5 will be administered by infusion  directly into the
pleural  cavity.  This trial is  primarily  designed  to obtain  safety and dose
response

                                     Page 5

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data, and secondarily to obtain evidence of efficacy,  including tumor stasis or
regression and improvement in cancer-associated biological markers.

         PT-5 requires a source of radioactive rhenium,  preferably rhenium-188.
This  isotope can be  produced  by a variety of  methods,  including a generator
system;  however,  clinical grade radioactive rhenium is not currently available
in the United States.  The Company is aware of an experimental  generator system
developed  in  the  United  States  by Oak  Ridge  National  Laboratory,  and an
additional  experimental  generator system available in Europe. The Company does
not intend to seek to commercialize  any source of radioactive  rhenium,  but is
aware of other companies seeking to commercialize radioactive rhenium. There can
be no assurance  that,  regardless of the status of product  development  by the
Company,  any acceptable  form of radioactive  rhenium will ever be commercially
available in the United States or other  countries at acceptable  prices,  if at
all, in which  event the  Company may never be able to develop or  commercialize
PT-5.

         The Company is  discussing  entering into a  collaborative  arrangement
with a third  party to use a specific  somatostatin  analog  for PT-5,  and both
parties are waiting to evaluate  the  results of  preliminary  clinical  trials.
There  can be no  assurance  that  the  Company  will  be  able  to  conclude  a
collaborative  arrangement on acceptable terms, if at all. If the Company cannot
conclude such  arrangement,  the Company will either abandon PT-5 development or
seek to develop a substitute using MIDAS  technology.  There can be no assurance
that the Company will be able to enter into an arrangement with another party on
acceptable  terms if at all, or will be able to develop a substitute using MIDAS
technology in a reasonable  period of time, or at all. There can be no assurance
that the Company's PT-5 development  program will be successful,  that PT-5 will
exhibit the expected  biological  results in humans,  that PT-5 will prove to be
safe and  efficacious  in  clinical  trials,  that the  Company  will obtain the
required   regulatory   approvals  for  PT-5,   or   that  the  Company  or  its
collaborators  will be successful in obtaining  market  acceptance of PT-5.  The
Company or its  collaborators  may  encounter  problems  and delays  relating to
research and development,  regulatory  approval,  manufacturing and marketing of
PT-5.

RHOCHEK PRODUCT

         The  Company  had  manufactured  and  marketed,  under the  trade  name
RhoChek,  a quality  control  test  product  for  measuring  the  immunoreactive
fraction of radiolabeled  antibodies specific to certain cancer antigens. Due to
insufficient  sales,  the Company  discontinued  product sales of RhoChek in the
fiscal year ended June 30, 1997. See Item 6.

MARKETS FOR PRODUCTS

         The Company's  proposed  products and  technologies  are intended to be
utilized in two  distinct  pharmaceutical  markets.  One market,  intended to be
addressed by LeuTech,  PT-5 and certain  proposed  products  resulting  from the
Company's MIDAS technology, is the radiopharmaceutical market. The other market,
intended  to be  addressed  by other  proposed  products  resulting  from  MIDAS
technology, is the larger biopharmaceutical market.

         The  radiopharmaceutical  market involves both  diagnostic  imaging and
therapeutic applications.  For imaging, trace amounts of a radioisotope bound to
a radiopharmaceutical drug are injected into a patient and detected with nuclear
medicine   diagnostic   equipment,   generally  a  gamma  camera.  For  therapy,
radioisotopes which emit radiation lethal to cancer cells are employed.

                                     Page 6

<PAGE>



         The Company  believes that proposed  products  resulting from its MIDAS
technology  can be used for a variety of  biopharmaceutical  applications  where
non-radioactive but  receptor-specific  drugs are desired.  The Company believes
the MIDAS technology may be applicable to a number of disease states,  including
immune  disorders,  cancer,  and cardiac therapy.  There are a limited number of
receptor-specific,  peptide-based drugs commercially  available,  but none which
employ a  metallopeptide.  There can be no assurance that MIDAS  technology will
result in the development of any such drugs.

RESEARCH AND DEVELOPMENT EXPENDITURES

         In the fiscal  year ended June 30,  1997 and the ten months  ended June
30, 1996 the Company spent  $3,409,983 and $869,896,  respectively,  on research
and development activities.

GRANTS AND COLLABORATIVE RESEARCH

         The Company applies for grants with the NIH and other  federally-funded
agencies  ("Research  Grants") to develop its products and  technologies.  Since
inception,  the  Company has been  awarded  over $2.8  million in  peer-reviewed
Research  Grants.  During the fiscal year ended June 30,  1997,  the Company had
four active Phase I SBIR Research  Grants.  Generally,  the maximum  amount of a
Phase I SBIR Research  Grant is $100,000,  and the maximum  amount of a Phase II
SBIR Research  Grant is $750,000.  There can be no assurance that any additional
Research Grants will be awarded.

         The Company  has,  where  scientifically  or  technologically  merited,
actively solicited  Cooperative  Research and Development  Agreements  ("CRADA")
with agencies of the federal  government,  involving  collaborative  development
activities with the Company. The Company currently has no active CRADAs, but has
completed  CRADAs  with Los  Alamos  National  Laboratory,  Brookhaven  National
Laboratory,  Oak Ridge  National  Laboratory  and  Sandia  National  Laboratory,
relating primarily to radiopharmaceutical drug development,  including PT-5, and
animal studies of proposed radiopharmaceutical products.

COMPETITION

         The  biopharmaceutical  and  radiopharmaceutical  industries are highly
competitive.  In the biopharmaceutical industry, there are a number of companies
developing  peptide-based  drugs,  including  companies  exploring  a number  of
different approaches to making  conformationally-constrained  short peptides for
use as therapeutic drugs. In the radiopharmaceutical industry, there are several
companies   devoted  to   development   and   commercialization   of  monoclonal
antibody-based  products and  peptide-based  products.  The Company is likely to
encounter  significant   competition  with  respect  to  its  proposed  products
currently under development. Many of the Company's competitors which are engaged
in  the   biopharmaceutical   field,   and  in  particular  the  development  of
peptide-based  products,  have substantially greater financial and technological
resources and marketing  capabilities than the Company,  and have  significantly
greater   experience  in  research  and  development.   Many  of  the  Company's
competitors  which  are  engaged  in  the  radiopharmaceutical   field,  and  in
particular the development of antibody- and peptide-based products, have greater
financial  and  technological  resources  and  marketing  capabilities  than the
Company, and have significantly  greater experience in research and development.
Accordingly,  the Company's  competitors may succeed in developing  products and
underlying  technologies  more  rapidly  than  the  Company,  and in  developing
products  that are more  effective  and useful and are less costly than any that
may be  developed  by the  Company,  and may  also be more  successful  than the
Company in  manufacturing  and marketing such products.  Academic  institutions,
hospitals,   governmental   agencies  and  other  public  and  private  research
organizations are also conducting research and seeking patent protection and may
develop competing products or technologies on their own or through collaborative
arrangements.

                                     Page 7

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         The Company  believes  that the  technological  attributes  of LeuTech,
including  the ease of  preparation,  rapidity  of imaging,  apparent  targeting
specificity and use of technetium-99m  (the most widely available  radioisotope)
will enable the Company to compete  effectively  in this  market.  However,  the
Company is aware of at least one company  developing an  antibody-based  product
which may  compete  with  LeuTech as to certain  indications,  which  product is
marketed in certain  European  countries  and for which  regulatory  approval is
pending  in the United  States.  The  Company  is also aware of another  company
developing  a  peptide-based  product  which may also compete with LeuTech as to
certain indications.

         The Company is aware of a number of companies  developing  technologies
relating  to the use of  peptides  as drugs,  including  a variety of  different
approaches to making conformationally-constrained short peptides.

         The Company is pursuing areas of product  development in which there is
the potential for extensive technological innovation in relatively short periods
of time. The Company's  competitors may succeed in developing  products that are
safer or more effective  than those of the Company's  proposed  products.  Rapid
technological  change or  developments  by others  may  result in the  Company's
proposed products becoming obsolete or non-competitive.

PATENTS AND PROPRIETARY INFORMATION

         The Company  aggressively seeks patent protection for its technology in
the United  States and,  selectively,  in those foreign  countries  where in the
Company's  judgment  such  protection  is  important to the  development  of the
Company's business.

         The  Company's  patents  and  pending   applications  are  directed  to
radiolabeling of antibodies,  antibody fragments,  and peptides; MIDAS peptides;
and to methods for making and using the foregoing in diagnostic and  therapeutic
applications.  The Company owns or has rights to 16 U.S. patents,  eight pending
U.S.  patent  applications,  four  allowed  U.S.  patent  applications  and nine
counterpart   patents  and  eight  pending   applications  in  selected  foreign
countries.

         Certain of the patents and  pending  applications  owned by the Company
have been  assigned to affiliates  of Aberlyn  Holding Co.,  Inc.  (collectively
"Aberlyn")  to secure  long-term  financing  but the  Company has  retained  the
exclusive  right to practice  these patents  itself and to grant  licenses under
these  patents to third  parties.  The  Company  is  obligated  to make  monthly
payments to Aberlyn in discharge of the Company's debt obligation of $91,695 per
month through May 1, 1999. On  completion of scheduled  payments,  all rights to
the patents and pending  applications  will be assigned to the  Company.  In the
event of default by the Company, Aberlyn has the right to require the Company to
cease using the patents, and to sell or exclusively license the patents to other
parties.  The patents and pending  applications  pertain to LeuTech and PT-5. In
addition,  the Company has semi-exclusive rights in a basic United States patent
relating to direct radiolabeling of antibodies, and its Canadian counterpart.

         Two of the Company's  basic U.S.  patents for direct  radiolabeling  of
antibodies and other proteins were involved in a  priority-of-invention  contest
(interference) in the U.S. Patent and Trademark Office with a patent application
owned by a third party.  This  proceeding  has been  settled,  and the Company's
patents  have  emerged  from  reissue  proceedings  in  which  the  scope of the
Company's  claims has been  somewhat  limited.  The  Company  believes  that the
current claim scope will not materially  adversely affect the Company's  current
product development plans, and is sufficient to protect the Company's underlying
inventions.

                                     Page 8

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         One of the Company's granted European patents (directed to selection of
patient-specific  antibody cocktails) is involved in an opposition proceeding at
the European Patent Office. The Company has received a favorable first decision,
but the opposing party has filed an appeal.  The Company believes that the final
outcome of this  proceeding,  even if adverse  to the  Company,  will not have a
material adverse effect on the Company's current product development plans.

         The Company's success will depend in substantial part on its ability to
obtain  patents,  defend and enforce its  patents,  maintain  trade  secrets and
operate without  infringing upon the proprietary  rights of others,  both in the
United States and abroad.

         In  general,   the  patent   positions   of   companies   relying  upon
biotechnology  are highly  uncertain  in general and involve  complex  legal and
factual questions.  To date there has emerged no consistent policy regarding the
breadth of claims that are properly accorded to biotechnology patents. There can
thus be no assurance that patents will issue from the patent  applications filed
by the Company or its  licensors or that the scope of any claims  granted in any
patent will provide meaningful proprietary protection or a competitive advantage
to the Company. There can be no assurance that the validity or enforceability of
patents  issued or licensed to the Company will not be  challenged by others or,
if challenged, will be upheld by a court. In addition, there can be no assurance
that  competitors  will not be able to circumvent any patents issued or licensed
to the Company.  In the United  States,  patent  applications  are maintained in
secrecy until they issue as patents,  and thus  publications  in the  scientific
literature lag behind actual discoveries. Scientific publications also generally
appear  after a patent  application,  if any,  is filed.  As a result of delayed
publication, the Company cannot be certain that its scientists were the first to
make inventions covered by its patents and patent applications.

         In the event a third party has also filed a patent application relating
to an  invention  claimed in a Company  patent  application,  the Company may be
required to participate in an interference  proceeding adjudicated by the United
States  Patent and  Trademark  Office to determine  priority of  invention.  The
possibility  of  an   interference   proceeding   could  result  in  substantial
uncertainties  and  cost  for the  Company,  even  if the  eventual  outcome  is
favorable to the Company.  An adverse outcome could result in the Company losing
patent  protection for the subject of the  interference,  subject the Company to
significant  liabilities  to third  parties  and  require  the Company to obtain
licenses  from  third  parties  at  undetermined  cost  or to  cease  using  the
technology.

         While no patent that would be infringed by manufacture,  use or sale of
the Company's  proposed  products has come to the attention of the Company,  the
Company's  proposed  products are still in the  development  stage,  and neither
their  formulations  nor their method of  manufacture  is  finalized.  Moreover,
patents,  the claims of which would be  infringed  by the  Company's  commercial
activities,  might not have yet been issued. There can thus be no assurance that
the  manufacture,  use or sale  of the  Company's  proposed  products  will  not
infringe  patent  rights  of  others.   The  Company  may  be  unable  to  avoid
infringement  of any such  patents  and may have to seek a  license,  defend  an
infringement  action, or challenge the validity of such patents in court.  There
can be no assurance that a license will be available to the Company,  if at all,
upon terms and  conditions  acceptable  to the Company or that the Company  will
prevail  in  any  patent  litigation.  Patent  litigation  is  costly  and  time
consuming,  and there can be no assurance that the Company will have  sufficient
resources  to pursue such  litigation.  If the Company does not obtain a license
under any such patents, is found liable for infringement, or is not able to have
them declared invalid,  the Company may be liable for significant money damages,
may encounter significant delays in bringing products to market,

                                     Page 9

<PAGE>



or may be  precluded  from  participating  in the  manufacture,  use or  sale of
products or methods of treatment covered by such patents.

         The Company relies substantially in its product development  activities
on certain  technologies  which are neither  patentable nor  proprietary and are
therefore potentially available to the Company's  competitors.  The Company also
relies on certain  proprietary  technologies  (trade secrets and know-how) which
are not  patentable.  Although  the  Company  has  taken  steps to  protect  its
unpatented   trade   secrets  and   know-how,   in  part   through  the  use  of
confidentiality  agreements  with its employees,  consultants and certain of its
contractors,  there  can be no  assurance  that  these  agreements  will  not be
breached,  that the Company would have adequate  remedies for any breach or that
the Company's trade secrets will not otherwise  become known or be independently
developed or discovered by competitors.  If the Company's employees,  scientific
consultants or collaborators develop inventions or processes  independently that
may be applicable to the Company's product candidates,  disputes may arise about
ownership  of  proprietary  rights  to  those  inventions  and  processes.  Such
inventions and processes will not necessarily become the Company's property, but
may remain the  property of those  persons or their  employers.  Protracted  and
costly  litigation  could be necessary to enforce and determine the scope of the
Company's  proprietary  rights.  Failure to obtain or maintain  patent and trade
secret protection,  for any reason,  could have a material adverse effect on the
Company.

         Certain of the Company's  patents are directed to inventions  developed
within  the  Company or within  academic  institutions  from  which the  Company
earlier acquired rights to such patents with funds from United States government
agencies.  As a result of these  arrangements,  the United States government may
have rights in certain inventions developed during the course of the performance
of federally  funded  projects as required by law or agreements with the funding
agency.

         Several  bills  affecting  patent  rights have been  introduced  in the
United  States  Congress.  These bills  address  various  aspects of patent law,
including  publication  of pending  patent  applications,  modifications  of the
patent  term,  re-examination,  subject  matter  and  enforceability.  It is not
certain  whether  any of these  bills will be enacted  into law or what form new
laws may take.  Accordingly,  the effect of legislative  change on the Company's
intellectual property estate is uncertain.

GOVERNMENTAL REGULATION

         The  manufacture  and  marketing  of the  Company's  proposed  products
requires  approval of the FDA and comparable  agencies in foreign  countries and
state regulatory authorities.  The FDA has established regulations and guidances
which apply, among other things, to the clinical testing, manufacturing, safety,
efficacy,  labeling, storage, record keeping, approval,  advertising,  promotion
and marketing of the Company's proposed products.  Noncompliance with applicable
requirements  can result in fines,  recalls or  seizures of  products,  total or
partial  suspension  of  production,  refusal  of the FDA to  approve  marketing
applications and criminal prosecution.

         In most cases, there is a substantial period of time between conception
of a proposed product and its approval for commercial sale.  Determining product
formulation  and  manufacturing  can take a number of years to complete,  as can
pre-clinical studies. Clinical trials and related studies can also take a number
of  years  to  complete.  The  period  between  the  date  of  submission  of an
application  for  approval  to market  and the date of  approval  by the FDA has
averaged  two to four  years  for  diagnostic  imaging  products,  although  the
approval process may take longer.  The length of time of the approval process is
a function of a number of variables, including the quality of the submission and
studies  presented,  the potential  contribution  that the proposed product will
make in improving the treatment of the disease in question and

                                     Page 10

<PAGE>



the  workload at the FDA.  There can be no assurance  that any of the  Company's
proposed products will successfully proceed through the approval process or that
any of the proposed  products  will be approved in any specific  period of time.
Depending  upon  marketing  and  distribution   plans  and  arrangements  for  a
particular  product,  the Company may require  additional time before a proposed
product can be made available for commercial sale, if at all.

         The steps required before  pharmaceutical  products can be produced and
marketed usually include  pre-clinical  non-human studies,  the filing of an IND
application,  clinical trials and the filing and approval of a Biologics License
Application  ("BLA")  for  products  classified  as  "biologics"  or filing  and
approval of a New Drug Application ("NDA") for drug products. LeuTech is subject
to the  requirement  of a BLA,  while PT-5 and  proposed  products  based on the
Company's MIDAS technology are subject to the requirement of a NDA.

         Pre-clinical  studies are  conducted  in the  laboratory  and in animal
model systems to gain preliminary information on the drug's effectiveness and to
identify  major safety  problems.  The results of these studies are submitted to
the FDA as part of the IND  application  before approval can be obtained for the
commencement of testing in humans.  The clinical  testing program required for a
new biological or  pharmaceutical  product  typically  involves three sequential
phases, but the phases may overlap. In the initial clinical evaluation, Phase I,
the product is tested for safety, dosage tolerance, distribution,  excretion and
pharmacodynamics.  Phase II involves studies in a limited patient populations to
evaluate the effectiveness of the product for a particular indication, to refine
optimal dosage and schedules of  administration,  and to identify  possible side
effects and risks. For diagnostic imaging agents, such as LeuTech, typically the
smallest quantity of product producing satisfactory images will be employed. For
therapeutic  products  the side  effects  and risks of  increased  doses must be
balanced against increased  therapeutic benefits.  For radiolabeled  therapeutic
products,  such as PT-5, the radiation dose to critical organs provides an upper
limit to the dosage.  When a product appears to be effective in Phase II trials,
it is then evaluated in Phase III clinical  trials.  Phase III trials consist of
additional  testing for effectiveness and safety with an expanded patient group,
usually at  multiple  test sites.  Therapeutic  products  are often  compared to
standard   treatments,   if  such  treatments   exist,  to  determine   relative
effectiveness in randomized trials.

         When Phase III studies are  complete,  the results of the  pre-clinical
and clinical studies, along with manufacturing information, are submitted to the
FDA in the  form  of  either  a BLA or a NDA.  Both  the  BLA  and  NDA  involve
considerable  data  collection,  verification  and analysis,  the preparation of
summaries of the  production  and testing  processes,  pre-clinical  studies and
clinical trials. The FDA must approve the BLA or NDA, as applicable,  before the
product may be marketed.  The FDA may deny a BLA or NDA if applicable regulatory
criteria are not satisfied,  may require additional  testing or information,  or
may require  post-marketing  testing,  including extensive Phase IV studies, and
surveillance  to monitor  the  effects of the  product in general  use.  Product
approvals  may be  withdrawn  if  compliance  with  regulatory  standards is not
maintained or if problems occur following initial  marketing.  In addition,  the
FDA may in some  circumstances  impose  restrictions on the use of the drug that
may limit its market potential.

         In addition to obtaining  either BLA or NDA  approval  from the FDA for
any of the Company's proposed products,  if the proposed product is manufactured
in the United  States the drug  manufacturing  establishment  must be registered
with,  and  inspected by, the FDA. Such drug  manufacturing  establishments  are
subject to biennial inspections by the FDA, and must comply with GMP regulations
enforced by the FDA. To supply  products for use in the United  States,  foreign
manufacturing  establishments  must  comply with GMP and are subject to periodic
inspection by the FDA or by corresponding regulatory agencies in

                                     Page 11

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such other countries under reciprocal agreements with the FDA. In complying with
standards established by the FDA, manufacturing  establishments must continue to
expend time,  money and effort in the areas of production and quality control to
ensure full  technical  compliance.  Components of LeuTech are  manufactured  by
contract  manufacturing  establishments both in the United States and in foreign
countries,  and the  Company  anticipates  that  PT-5  will be  manufactured  by
contract manufacturing establishments. The Company is dependent on such contract
manufacturing  establishments  for, and will have only limited control over, the
commercial  manufacturing  of its proposed  products in compliance  with FDA and
other regulatory requirements.

         The Company has very limited experience in conducting  clinical trials.
Clinical  trials are  conducted  in  accordance  with FDA  regulations  covering
protection  of human  subjects and clinical  practice  protocols  detailing  the
objectives  of the study,  parameters  for  monitoring  safety and  criteria for
determining effectiveness. The Company will either need to rely on third parties
to design and administer  required  clinical trials or expend  resources to hire
additional  personnel  to  administer  such  clinical  trials.  There  can be no
assurance  that the Company will be able to find  appropriate  third  parties to
design  and  administer  clinical  trials  or that  the  Company  will  have the
resources to hire personnel to administer clinical trials.

         No proposed  product being  evaluated by the Company has been submitted
for  approval  or  approved  by the FDA or any other  regulatory  authority  for
marketing,  and there can be no  assurance  that any such  product  will ever be
approved  for  marketing or that the Company will be able to obtain the labeling
claims desired for its proposed products. The Company is and will continue to be
dependent upon laboratories and medical institutions conducting its pre-clinical
studies and clinical  trials to maintain both good  laboratory and good clinical
practices  consistent  with FDA  regulations.  Data obtained  from  pre-clinical
studies and clinical trials are subject to varying  interpretations  which could
delay,  limit or prevent FDA  regulatory  approval.  Delays or rejections may be
encountered based upon changes in FDA policy for drug approval during the period
of development and FDA regulatory review. Similar delays also may be encountered
in foreign countries.

         There can be no assurance that FDA or other regulatory approval for any
proposed products developed by the Company will be granted on a timely basis, or
at all. Delay in obtaining or failure to obtain such  regulatory  approvals will
have a material adverse effect on the Company.

MANUFACTURING AND MARKETING

         To be  successful,  the  Company's  products  must be  manufactured  in
commercial  quantities  under  GMP  requirements  prescribed  by the  FDA and at
acceptable  costs.  The  Company  has not yet  manufactured  any  pharmaceutical
products in commercial  quantities and currently does not have the facilities to
manufacture  any products in commercial  quantities  under GMP. In the event the
Company  determines  to  establish a  manufacturing  facility,  it will  require
substantial additional funds, the hiring and retention of significant additional
personnel  and  compliance  with  extensive  regulations  applicable  to  such a
facility.   The  Company  has  no  experience   in   commercial   pharmaceutical
manufacturing,  and there can be no  assurance  that the Company will be able to
establish such a facility successfully and, if established, that it will be able
to manufacture products in commercial quantities for sale at competitive prices.
If the  Company  determines  to rely on  collaborators,  licensees  or  contract
manufacturers for the commercial  manufacture of its products,  the Company will
be dependent on such  corporate  partners or other  entities  for, and will have
only limited control over, the commercial  manufacturing of its products.  While
the Company has entered into  manufacturing  arrangements as to certain portions
of the  manufacture  of LeuTech  under GMP,  there can be no assurance  that the
contract manufacturer will perform as agreed or will remain in the contract

                                     Page 12

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manufacturing business for the time required by the Company, or that the Company
will be able to enter  into  such  manufacturing  arrangements  as to  remaining
portions of the  manufacture  of  LeuTech.  There can be no  assurance  that the
Company will be able to enter into any such manufacturing arrangements as to its
other proposed products on acceptable terms, if at all.

         LeuTech requires  purified  monoclonal  antibody,  made from a specific
parent cell line.  There are, on a global  basis,  a limited  number of contract
manufacturers capable of producing purified monoclonal  antibodies.  The Company
has  entered  into   manufacturing   arrangements   with  third-party   contract
manufacturers  for GMP production and  purification  of the monoclonal  antibody
required for LeuTech and for GMP vialing and lyophilization of LeuTech.

         Proposed  products   resulting  from  MIDAS  technology  and  PT-5  are
synthetic  peptides.  The peptides are synthesized from readily  available amino
acids, and the production  process  involves  well-established  technology.  The
Company currently contracts with third-party manufacturers for the production of
peptides and anticipates doing so in the future.

         PT-5  requires  a  source  of  radioactive   rhenium  in  order  to  be
commercialized.  There can be no  assurance  that,  regardless  of the status of
product  development by the Company,  any acceptable form of radioactive rhenium
will ever be commercially available in the United States or other countries. See
"Direct  Radiolabeling  Technology -- PT-5 Cancer  Therapeutic  Product" in this
Item 1.

         The  Company  intends  to  package  and  ship  its  radiopharmaceutical
products in the form of non-radioactive  kits. Prior to patient  administration,
the product would be radiolabeled with the specified radioisotope,  generally by
a specialized  radiopharmacy.  The Company does not intend to sell or distribute
any radioactive substance.

         The Company has limited experience in marketing, including distribution
and sales, of  pharmaceutical  products,  and will have to develop a sales force
and/or  rely on its  collaborators,  licensees  or  arrangements  with others to
provide  for the  marketing,  distribution  and  sales of its  products.  If the
Company  determines to rely on  collaborators,  licensees or  arrangements  with
others for the marketing,  distribution and sales of its proposed products,  the
Company will be dependent  on such  collaborators  and others for, and will have
only limited  control over,  marketing,  distribution  and sales of its proposed
products.

         Successful  sales of the  Company's  proposed  products  in the  United
States  and  other  countries  will  depend  on  the  availability  of  adequate
reimbursement  from third-party  payors such as governmental  entities,  managed
care  organizations and private insurance plans.  Reimbursement by a third-party
payor may depend on a number of factors,  including  the  payor's  determination
that  use of a  product  is  safe  and  efficacious,  neither  experimental  nor
investigational,  medically necessary,  appropriate for the specific patient and
cost  effective.  Since  reimbursement  approval  is  required  from each  payor
individually,  seeking such approvals is a  time-consuming  and costly  process.
Third-party payors routinely limit reimbursement  coverage and in many instances
are exerting  significant  pressure on medical  suppliers to lower their prices.
There is significant  uncertainty concerning  third-party  reimbursement for the
use of any pharmaceutical product incorporating new technology,  and there is no
assurance  that  third-party  reimbursement  will be available for the Company's
proposed products,  or that such reimbursement,  if obtained,  will be adequate.
Less than full  reimbursement by governmental and other  third-party  payors for
the Company's  products would  adversely  affect the market  acceptance of these
products and would also have a material adverse effect on the Company.  Further,
health care reimbursement systems vary from country to country, and there can be

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no assurance  that  third-party  reimbursement  will be made  available  for the
Company's proposed products under any other reimbursement system.

PRODUCT LIABILITY AND INSURANCE

         The Company's  business may be affected by potential  product liability
risks which are inherent in the testing, manufacturing and marketing of proposed
pharmaceutical  products  to be  developed  by  the  Company.  There  can  be no
assurance  that  product  liability  claims  will not be  asserted  against  the
Company, its collaborators or licensees.  The use of proposed products developed
by the  Company in  clinical  trials and the  subsequent  sale of such  proposed
products is likely to cause the Company to bear all or a portion of those risks.
Such litigation claims could have a material adverse effect on the Company.  The
Company  has  liability  insurance  providing  up  to  $1,000,000  coverage  per
occurrence  and in the aggregate as to certain  clinical  trial risks,  and will
seek   to   obtain   additional   product   liability   insurance   before   the
commercialization  of its  products.  There can be no assurance,  however,  that
insurance  will be available to the Company on acceptable  terms,  if at all, or
that such  coverage  once  obtained  would be  adequate  to protect  the Company
against  future  claims or that a medical  malpractice  or other claim would not
materially  and  adversely  affect  the  Company.  Furthermore,  there can be no
assurance  that any  collaborators  or  licensees  of the Company  will agree to
indemnify the Company, be sufficiently insured or have a net worth sufficient to
satisfy any such product liability  claims. In addition,  products such as those
proposed  to be sold by the  Company  may be subject  to recall  for  unforeseen
reasons. Such a recall could have a material adverse effect on the Company.

EMPLOYEES

         As of June 30, 1997, the Company employed 16 persons full time, of whom
11 were engaged in research  and  development  activities  and 5 were engaged in
administration and management. Of the Company's employees, 4 hold Ph.D. degrees.
The Company, from time to time, hires scientific  consultants to work on certain
of its research and development programs.  The Company believes that it has been
successful in attracting skilled and experienced scientific personnel;  however,
competition for such personnel is intense.

         None of the Company's  employees is covered by a collective  bargaining
agreement. The Company's employees have executed confidentiality agreements. The
Company considers relations with its employees to be good.

          The Company  relies,  in  substantial  part,  and for the  foreseeable
future will rely, on certain independent organizations, advisors and consultants
to  provide   certain   services,   including   substantially   all  aspects  of
manufacturing,  regulatory  approval  and clinical  management.  There can be no
assurance  that  the  services  of  independent   organizations,   advisors  and
consultants  will continue to be available to the Company on a timely basis when
needed,  or that the Company could find  qualified  replacements.  The Company's
advisors  and   consultants   generally   sign   agreements   that  provide  for
confidentiality of the Company's proprietary information.  However, there can be
no assurance  that the Company will be able to maintain the  confidentiality  of
the  Company's  technology,  the  dissemination  of which  could have a material
adverse effect on the Company.

HISTORY AND MERGER

          General.  The Company was incorporated under the laws of the  State of
Delaware on November 21, 1986.  From  November 4, 1993,  when the Company,  then
named Interfilm, acquired Interfilm

                                     Page 14

<PAGE>



Technologies,  Inc., a New York corporation,  through May 9, 1995, Interfilm was
primarily  engaged in the  business  of  exploiting  the  rights  related to its
interactive motion picture process, including the production and distribution of
interactive  motion pictures for initial exhibition in theaters and subsequently
in enhanced versions for distribution to the home market.  Interfilm consummated
an initial  public  offering on October 28, 1993, and on May 10, 1995, the Board
of Directors of Interfilm  decided to  substantially  curtail the  operations of
Interfilm and its subsidiaries.  Interfilm conducted no business activities from
May 10, 1995 until June 25, 1996.

         Merger with  RhoMed.  On June 25, 1996,  a newly  formed,  wholly-owned
subsidiary  of  Interfilm,  Interfilm  Acquisition  Corporation,  a  New  Mexico
corporation,  merged with and into RhoMed, a New Mexico corporation,  and all of
RhoMed's  outstanding  equity  securities were  ultimately  exchanged for equity
securities  of the Company  (the  "Merger").  As a result of the Merger,  RhoMed
became a  wholly-owned  subsidiary  of the  Company,  with the holders of RhoMed
preferred  stock and  RhoMed  common  stock  (including  the  holders of "RhoMed
Securities" as hereafter defined) receiving an aggregate of an approximately 96%
interest  in the equity  securities  of the  Company on a  fully-diluted  basis.
Additionally,  all  warrants  and  options to  purchase  common  stock of RhoMed
outstanding immediately prior to the Merger (the "RhoMed Securities"), including
without  limitation,  any rights underlying  RhoMed's qualified and nonqualified
stock option plans, were  automatically  converted into rights to receive,  upon
exercise,  Common  Stock,  in the same manner in which  shares of RhoMed  common
stock were  converted.  Since the former  stockholders  of RhoMed  acquired,  by
reason of the Merger, more than a 50% controlling  interest in the Company,  the
Merger has been treated,  for  accounting  purposes,  as a reverse  acquisition.
Consequently,  the historical  financial statements of the Company prior to June
25, 1996, are those of RhoMed.

         In  connection  with  the  Merger,   certain   pre-Merger   assets  and
liabilities of the Company and one of its wholly-owned subsidiaries,  consisting
principally  of  certain  intellectual  property  and  litigation  claims,  were
transferred to an unaffiliated limited liability  partnership for the benefit of
the Company's pre-Merger  stockholders as of a record date of June 21, 1996. See
Item 3.

         On July 19,  1996,  the  Company  filed an  amendment  to its  Restated
Certificate of Incorporation, as amended ("Certificate of Incorporation"), which
(i) effected the change of name of the Company from  Interfilm,  Inc. to Palatin
Technologies,  Inc., (ii) increased the total number of authorized shares of the
Company's  Common  Stock from  10,000,000  to  25,000,000  and (iii)  effected a
1-for-10 reverse split of the Common Stock (the "Charter Amendment").

         Reverse Stock Split and Increase in Authorized Capital. On September 5,
1997, the Company filed an amendment to its Certificate of Incorporation,  which
(i)  increased the total number of  authorized  shares of the  Company's  Common
Stock from 25,000,000 to 75,000,000 and the total number of authorized shares of
the Company's  preferred  stock from 2,000,000 to 10,000,000 and (ii) effected a
1-for-4 reverse split of the Common Stock (the "Second Charter Amendment").

         As a  result  of the  Merger,  Charter  Amendment  and  Second  Charter
Amendment, each share of RhoMed preferred stock was converted into approximately
 .1167  shares  of  Common  Stock,  and each  share of  RhoMed  common  stock was
converted into approximately .0461 shares of Common Stock.

                                     Page 15

<PAGE>



IMPORTANT FACTORS REGARDING FORWARD-LOOKING STATEMENTS

         The  following  important  factors,   among  others,  could  cause  the
Company's actual results,  performance or achievements,  or industry results, to
differ  materially  from  those  expressed  in  the  Company's   forward-looking
statements  in this Report and presented  elsewhere by  management  from time to
time.

         Early  Stage  of  Development;   Uncertainty  of  Product  Development;
Technological  Uncertainty.  The Company is at an early stage of development and
has not yet completed the  development of any products based on either its MIDAS
technology or its direct radiolabeling technology.  Accordingly, the Company has
not begun to market or generate revenues from the  commercialization of any such
products.  It will be a number  of  years,  if ever,  before  the  Company  will
recognize  significant  revenues from product sales or royalties.  The Company's
technologies   and  products   under   development   will  require   significant
time-consuming and costly research,  development,  preclinical studies, clinical
testing,  regulatory  approval and significant  additional  investment  prior to
their  commercialization,  which may never occur. There can be no assurance that
the Company's  research and  development  programs will be successful,  that its
products  will  exhibit  the  expected  biological  results in humans,  that its
products  will prove to be safe and  efficacious,  that its products will obtain
the  required  regulatory  approvals,  demonstrate  substantial  therapeutic  or
diagnostic benefit, be commercialized on a timely basis, experience no design or
manufacturing  problems,  be  manufactured on a large scale, or be economical to
market, or that the Company or its collaborators will be successful in obtaining
market  acceptance  of any of the  Company's  products  or  generate  sufficient
revenue to support research and development programs.  There can be no assurance
that the Company will be  successful  in entering  into  strategic  alliances or
collaborative  arrangements  on commercially  reasonable  terms, if at all, that
such arrangements will be successful, or that the parties with which the Company
will  establish   arrangements   will  perform  their   obligations  under  such
arrangements. The Company or its collaborators may encounter problems and delays
relating to research and development,  regulatory  approval,  manufacturing  and
marketing.  The failure by the Company to successfully address such problems and
delays  would have a material  adverse  effect on the Company.  In addition,  no
assurance  can be  given  that  proprietary  rights  of third  parties  will not
preclude the Company from marketing its proposed  products or that third parties
will not market superior or equivalent products. See this Item 1 and Item 6.

         History of Operating  Losses and Accumulated  Deficit.  The Company has
incurred net operating losses since its inception  (January 28, 1986) and, as of
June 30, 1997, had an accumulated deficit of approximately $13.4 million,  which
has increased to date. The Company anticipates  incurring additional losses over
at least the next several  years and such losses are expected to increase as the
Company  expands its research and development  activities  relating to its MIDAS
technology and its direct radiolabeling  technology.  To achieve  profitability,
the Company,  alone or with others,  must successfully  develop its technologies
and products,  conduct preclinical studies and clinical trials,  obtain required
regulatory  approvals and  successfully  manufacture,  introduce and market such
technologies  and products.  The time required to reach  profitability is highly
uncertain,  and  there  can be no  assurance  that the  Company  will be able to
achieve profitability on a sustained basis, if at all. See Item 6.

         Need for  Additional  Financing and Access to Capital.  The Company has
incurred negative cash flow from operations since its inception. The Company has
expended,  and will continue to expend in the future, if available,  substantial
funds to continue its research and development  programs,  including preclinical
studies and clinical  trials,  to seek regulatory  approval of its products,  to
develop manufacturing and marketing capabilities, and to fund the growth that is
expected to occur if any of its proposed  products  are approved for  marketing.
Further, the Company has significant long-term debt that is due and payable

                                     Page 16

<PAGE>



during the fiscal years ending June 30, 1998 and 1999. The Company  expects that
its existing capital  resources will be adequate to make scheduled debt payments
and to fund its  operations  through June 1998.  No assurance  can be given that
there will be no events  affecting the Company's  operations  that would deplete
available resources significantly before such time. The Company's future capital
requirements  depend  on  many  factors,  including  continued  progress  in its
research and  development  activities,  progress  with  preclinical  studies and
clinical  trials,  prosecuting and enforcing  patent claims,  technological  and
market developments, the ability of the Company to establish product development
arrangements,  the  cost  of  manufacturing  scale-up  and  effective  marketing
activities and  collaborative  or other  arrangements.  The Company will seek to
obtain additional funds through public or private  financings,  including equity
or debt financings,  collaborative or other arrangements with corporate partners
and others,  and from other sources.  No assurance can be given that  additional
financing  will be available when needed,  if at all, or on terms  acceptable to
the Company. If adequate additional funds are not available,  the Company may be
required  to  delay,  scale  back  or  eliminate  certain  of  its  research  or
development activities,  its manufacturing and marketing efforts, or require the
Company to license to third parties certain  products or  technologies  that the
Company would otherwise seek to commercialize  itself. If adequate funds are not
available,  there will be a material and adverse effect on the Company. See Item
6.

         Patents and  Proprietary  Rights,  No  Assurance of  Enforceability  or
Significant Competitive Advantage. In general, the patent positions of companies
relying upon  biotechnology  are highly  uncertain and involve complex legal and
factual questions. To date, there has emerged no consistent policy regarding the
breadth of claims that are properly accorded to biotechnology patents. There can
be no assurance  that patents will issue from the patent  applications  filed by
the  Company or its  licensors  or that the scope of any  claims  granted in any
patent will provide meaningful proprietary protection or a competitive advantage
to the Company. There can be no assurance that the validity or enforceability of
patents  issued or licensed to the Company will not be  challenged by others or,
if challenged, will be upheld by a court. In addition, there can be no assurance
that  competitors  will not be able to circumvent any patents issued or licensed
to the Company.  In the United  States,  patent  applications  are maintained in
secrecy  until  they  issue as  patents,  and thus  publications  in the  patent
literature lag behind actual discoveries. Scientific publications also generally
appear  after a patent  application,  if any,  is filed.  As a result of delayed
publication, the Company cannot be certain that its scientists were the first to
make inventions covered by its patents and patent applications.

         In the event another party has also filed a patent application relating
to an  invention  claimed in a Company  patent  application,  the Company may be
required to participate in an interference  proceeding adjudicated by the United
States  Patent and  Trademark  Office to determine  priority of  invention.  The
possibility  of  an   interference   proceeding   could  result  in  substantial
uncertainties  and  cost  for the  Company,  even  if the  eventual  outcome  is
favorable to the Company.  An adverse outcome could result in the Company losing
patent  protection for the subject of the  interference,  subject the Company to
significant  liabilities  to third  parties  and  require  the Company to obtain
license  rights from third  parties at  undetermined  cost or to cease using the
technology.

         While no valid patent that would be infringed  by  manufacture,  use or
sale  of the  Company's  proposed  products  has  come to the  attention  of the
Company, the Company's proposed products are still in the development stage, and
neither  their  formulations  nor their  method  of  manufacture  is  finalized.
Moreover,  patents  the  claims of which  would be  infringed  by the  Company's
commercial activities may not have issued as yet. There can thus be no assurance
that the manufacture,  use or sale of the Company's  proposed  products will not
infringe patent rights of others. The Company may be unable to avoid

                                     Page 17

<PAGE>



infringement  of any such  patents  and may have to seek a  license,  defend  an
infringement  action, or challenge the validity of such patents in court.  There
can be no assurance that a license will be available to the Company,  if at all,
upon terms and  conditions  acceptable  to the Company or that the Company  will
prevail  in  any  patent  litigation.  Patent  litigation  is  costly  and  time
consuming,  and there can be no assurance that the Company will have  sufficient
resources  to pursue such  litigation.  If the Company does not obtain a license
under any such patents, is found liable for infringement, or is not able to have
them declared invalid,  the Company may be liable for significant money damages,
may  encounter  significant  delays in bringing  products  to market,  or may be
precluded  from  participating  in the  manufacture,  use or sale of products or
methods of treatment covered by such patents.

         The Company relies substantially in its product development  activities
on certain  technologies  which are neither  patentable nor  proprietary and are
therefore potentially available to the Company's  competitors.  The Company also
relies on certain  proprietary  technologies  (trade secrets and know-how) which
are not  patentable.  Although  the  Company  has  taken  steps to  protect  its
unpatented   trade   secrets  and   know-how,   in  part   through  the  use  of
confidentiality  agreements  with its employees,  consultants and certain of its
contractors,  there  can be no  assurance  that  these  agreements  will  not be
breached,  that the Company would have adequate  remedies for any breach or that
the Company's trade secrets will not otherwise  become known or be independently
developed or discovered by competitors.  If the Company's employees,  scientific
consultants or collaborators develop inventions or processes  independently that
may be applicable to the Company's product candidates,  disputes may arise about
ownership  of  proprietary  rights  to  those  inventions  and  processes.  Such
inventions and processes will not necessarily become the Company's property, but
may remain the  property of those  persons or their  employers.  Protracted  and
costly  litigation  could be necessary to enforce and determine the scope of the
Company's  proprietary  rights.  Failure to obtain or maintain  patent and trade
secret protection,  for any reason,  could have a material adverse effect on the
Company.

         Certain of the Company's  patents are directed to inventions  developed
with  funds  from  United  States   government   agencies  or  within   academic
institutions from which the Company earlier acquired rights to such patents.  As
a result of these arrangements,  the United States government may have rights in
certain  inventions  developed during the course of the performance of federally
funded projects as required by law or agreements with the funding agency.

         Several  bills  affecting  patent  rights have been  introduced  in the
United  States  Congress.  These bills  address  various  aspects of patent law,
including publication of pending patent applications, modification of the patent
term,  re-examination,  subject  matter and  enforceability.  It is not  certain
whether any of these  bills will be enacted  into law and  whether,  as enacted,
they would  affect the  scope,  validity  and  enforceability  of the  Company's
patents.  Accordingly,  the  effect  of  legislative  change  on  the  Company's
intellectual  property  estate  is  uncertain.   See  "Patents  and  Proprietary
Information" in this Item 1.

         Uncertainty of Development of MIDAS Technology.  The Company is engaged
in research and development on a number of product  opportunities  for its MIDAS
technology,  including use as a thrombosis  imaging agent, an infection  imaging
agent and an  immunostimulatory  agent,  and believes that MIDAS  technology may
have medical  applications in a variety of areas,  including  immune  disorders,
cancers and  cardiology.  The Company intends to expand research and development
of MIDAS technology  applications  primarily  through  strategic  alliances with
other  entities.  No assurances can be made regarding the  establishment  or the
timing of such  alliances,  and the failure to  establish  such  alliances  on a
timely basis could limit the Company's  ability to develop MIDAS  technology and
could have a material  adverse  effect on the  Company.  The Company  expects to
devote resources to expand research and development of

                                     Page 18

<PAGE>



MIDAS technology to the extent funding is available.  No prediction can be made,
however,  as to when or  whether  the  areas in which  there are  ongoing  MIDAS
technology research projects will yield scientific discoveries,  or whether such
research projects will lead to commercial  products.  See "MIDAS  Technology" in
this Item 1.

         While the  Company has entered  into the Option  Agreement  with Nihon,
pursuant to which Nihon has an option to exclusively  license  certain  products
based on the Company's MIDAS  technology,  there can be no assurance that future
payments provided for in the Option Agreement will be made, that the Company and
Nihon will ever enter into a definitive license agreement,  or that a definitive
strategic  alliance between the Company and Nihon will result in the development
or commercialization of any product. In the event that Nihon gives notice of its
right to negotiate a license agreement, and the parties cannot agree on terms of
such license agreement,  the Company will be required to repay certain monies to
Nihon.  Failure to enter into a definitive license agreement,  or being required
to repay  certain  monies to Nihon,  may have a material  adverse  effect on the
Company. See Item 6.

         Uncertainty of Development of LeuTech.  The Company has entered into an
exclusive license agreement with the Wistar Institute for a defined field of use
for the  antibody  and cell  line  used for  LeuTech,  which  license  agreement
contains certain performance criteria.  Failure to meet the performance criteria
for any reason or any other event of default under the license agreement leading
to termination of the exclusive  license  agreement with Wistar  Institute would
have a material adverse effect on the Company.  While the Company has negotiated
a long-term contractual arrangement for the manufacture of the purified antibody
necessary for LeuTech,  there can be no assurance that such  contractor  will be
able to successfully  manufacture  purified  antibody for LeuTech on a sustained
basis, that such contractor will remain in the contract  manufacturing  business
for the time required by the Company,  or that the Company will be able to enter
into such contractual  arrangements as to other steps and components required to
manufacture  LeuTech.  Such  manufacture  must be done  under  GMP  requirements
prescribed by the FDA and other governmental  agencies. To date, the Company has
only manufactured  LeuTech in lots preparatory to initiating clinical trial use,
with  certain  manufacturing  processes  having been done under GMP, and has not
determined  whether  commercial  quantities of LeuTech in conformity  with these
standards can be manufactured on a sustained basis at an acceptable cost.

         While the Company intends to file an IND on LeuTech with the FDA on one
or more selected  indications  in the second half of 1997, and to complete Phase
III clinical trials and file  regulatory  applications to market with the FDA in
the second half of 1998,  there can be no assurance  that the Company's  LeuTech
development  program will be successful,  that the FDA will permit the Company's
planned  clinical  trials to  proceed,  that  LeuTech  will prove to be safe and
efficacious in clinical trials, that LeuTech can be manufactured in commercially
required  quantities on a sustained basis at an acceptable  price,  that LeuTech
will  obtain  the  required  regulatory  approvals  or that the  Company  or its
collaborators will be successful in obtaining market acceptance of LeuTech.  The
Company or its  collaborators  may  encounter  problems  and delays  relating to
research and development,  regulatory  approval,  manufacturing and marketing of
LeuTech.  Failure to develop,  obtain regulatory  approval for,  manufacture and
market  LeuTech on a timely  basis would have a material  adverse  effect on the
Company. See "Direct Labeling Technology" in this Item 1.

         Uncertainty of Development of PT-5. The Company is discussing  entering
into  a  collaborative  arrangement  with  a  third  party  to  use  a  specific
somatostatin analog for PT-5. There can be no assurance that the Company will be
able to enter into a collaborative  arrangement on acceptable  terms, if at all.
If the

                                     Page 19

<PAGE>



Company cannot conclude such  arrangement,  the Company will either abandon PT-5
development or seek to develop a substitute using MIDAS technology. There can be
no  assurance  that the Company will be able to enter into an  arrangement  with
another  party on  acceptable  terms  if at all,  or will be able to  develop  a
substitute  using MIDAS  technology  in a reasonable  period of time, or at all.
There can be no assurance  that the Company's PT-5  development  program will be
successful,  that PT-5 will exhibit the expected  biological  results in humans,
that PT-5 will prove to be safe and  efficacious  in clinical  trials,  that the
Company  will obtain the required  regulatory  approvals  for PT-5,  or that the
Company or its  collaborators  will be successful in obtaining market acceptance
of PT-5.  The Company or its  collaborators  may  encounter  problems and delays
relating to research and development,  regulatory  approval,  manufacturing  and
marketing of PT-5.

         In addition, PT-5 requires a source of radioactive rhenium,  preferably
rhenium-188.  This isotope can be produced by a variety of methods,  including a
generator system;  however,  clinical grade radioactive rhenium is not currently
available  in the  United  States.  The  Company  is  aware  of an  experimental
generator   system  developed  in  the  United  States  by  Oak  Ridge  National
Laboratory, and an additional experimental generator system available in Europe.
The Company does not intend to seek to  commercialize  any source of radioactive
rhenium,  but is aware of other companies  seeking to commercialize  radioactive
rhenium.  There can be no assurance  that,  regardless  of the status of product
development by the Company, any acceptable form of radioactive rhenium will ever
be commercially  available in the United States or other countries at acceptable
prices,  if at all,  in which  event the Company may never be able to develop or
commercialize PT-5. See "Direct Labeling Technology" in this Item 1.

         Government  Regulation;  No  Assurance of Product  Approval.  Research,
development,  testing, clinical trials, manufacture,  distribution,  advertising
and marketing,  including distribution and sale, of pharmaceutical  products are
subject to extensive regulation by governmental authorities in the United States
and other  countries.  Prior to marketing,  proposed  products  developed by the
Company must undergo an extensive  regulatory  approval  process required by the
FDA and by comparable agencies in other countries.  This process, which includes
preclinical  studies and clinical  trials of each proposed  product to establish
safety  and  effectiveness  and  confirmation  by the FDA that good  laboratory,
clinical  and  manufacturing   practices  were  maintained  during  testing  and
manufacturing,  can take many years,  requires the  expenditure  of  substantial
resources  and  gives  larger  companies  with  greater  financial  resources  a
competitive  advantage  over the Company.  To date,  no proposed  product  being
evaluated by the Company has been  submitted for approval or approved by the FDA
or any other regulatory  authority for marketing,  and there can be no assurance
that any such product  will ever be submitted or approved for  marketing or that
the Company will be able to obtain the labeling claims desired for its products.
The  Company is and will  continue to be  dependent  upon the  laboratories  and
medical  institutions  conducting its preclinical studies and clinical trials to
maintain both good  laboratory and good clinical  practices.  Data obtained from
preclinical  studies and clinical trials are subject to varying  interpretations
which  could  delay,  limit  or  prevent  FDA  regulatory  approval.  Delays  or
rejections may be encountered based upon changes in FDA policy for drug approval
during the period of development and FDA regulatory review.  Similar delays also
may be encountered in foreign countries.

         There can be no assurance that FDA or other regulatory approval for any
products  developed by the Company will be granted on a timely basis, if at all.
Delay  in  obtaining  or  failure  to  obtain  such  regulatory  approvals  will
materially adversely affect the introduction and marketing of any products which
may be developed by the Company as well as the Company's results of operations.

                                     Page 20

<PAGE>



         When and if approvals are granted,  the Company, the approved drug, the
manufacture of such drug and the  facilities in which such drug is  manufactured
are subject to ongoing  regulatory  review.  Subsequent  discovery of previously
unknown  problems may result in  restriction on a product's use or withdrawal of
the product from the market. Adverse government regulation that might arise from
future  legislative  or  administrative  action,  particularly  as it relates to
health care reform and product  pricing,  cannot be predicted.  See  "Government
Regulation" in this Item 1.

         No Commercial Manufacturing Capability or Experience. To be successful,
the Company's  products must be manufactured in commercial  quantities under GMP
requirements  prescribed by the FDA and at acceptable costs. The Company has not
yet  manufactured  any  pharmaceutical  products in  commercial  quantities  and
currently does not have the facilities to manufacture any products in commercial
quantities  under  GMP.  In the event the  Company  determines  to  establish  a
manufacturing facility, it will require substantial additional funds, the hiring
and retention of significant  additional personnel and compliance with extensive
regulations  applicable  to such a facility.  The Company has no  experience  in
commercial pharmaceutical manufacturing,  and there can be no assurance that the
Company  will  be  able  to  establish  such a  facility  successfully  and,  if
established,  that  it  will  be able  to  manufacture  products  in  commercial
quantities for sale at competitive  prices. If the Company determines to rely on
collaborators,   licensees  or  contract   manufacturers   for  the   commercial
manufacture  of its  products,  the Company will be dependent on such  corporate
partners or other  entities for, and will have only limited  control  over,  the
commercial  manufacturing  of its  products.  While the Company has entered into
manufacturing  arrangements as to certain portions of the manufacture of LeuTech
under GMP, there can be no assurance that the contract manufacturer will perform
as agreed or will remain in the  contract  manufacturing  business  for the time
required by the  Company,  or that the  Company  will be able to enter into such
manufacturing  arrangements  as to  remaining  portions  of the  manufacture  of
LeuTech.  There can be no assurance  that the Company will be able to enter into
any  such  manufacturing  arrangements  as to its  other  proposed  products  on
acceptable terms, if at all. See "Manufacturing and Marketing" in this Item 1.

         Limited Clinical Trial Experience. Before obtaining required regulatory
approvals for the  commercial  sale of its proposed  products,  the Company must
demonstrate  through clinical trials that such products are safe and efficacious
for use. The Company is in various stages of testing,  but has not yet filed any
IND applications.  The initiation and completion of clinical trials is dependent
upon many factors,  including FDA  acquiescence,  the  availability of qualified
clinical  investigators  and access to suitable patient  populations.  Delays in
initiating and completing  clinical  trials may result in increased  trial costs
and delays in FDA submissions, which could have a material adverse effect on the
Company. To date, the Company has very limited experience in conducting clinical
trials.  The Company  will  either  need to rely on third  parties to design and
conduct any required  clinical  trials or expend  resources  to hire  additional
personnel to administer such clinical trials. There can be no assurance that the
Company  will be able to find  appropriate  third  parties to design and conduct
clinical  trials  or  that it will  have  the  resources  to hire  personnel  to
administer clinical trials in-house.

         A  number  of  companies  in  the  biotechnology   and   pharmaceutical
industries have suffered  significant  setbacks in clinical  trials,  even after
showing  promising  results  in  earlier  studies  or  trials.  There  can be no
assurance  that the Company will not encounter  problems in its clinical  trials
that will cause the Company to delay or suspend its  clinical  trials,  that the
clinical  trials of its proposed  products  will be completed at all,  that such
testing  will  ultimately  demonstrate  the safety or efficacy of such  proposed
products or that any proposed  products  will receive  regulatory  approval on a
timely basis, if at all. If any such problems  occur,  there would be a material
adverse effect on the Company. See "Government Regulation" in this Item 1.

                                     Page 21

<PAGE>



         Limited Marketing, Distribution or Sales Capability and Experience. The
Company has limited experience in marketing pharmaceutical  products,  including
distribution and selling of pharmaceutical  products, and will have to develop a
sales force and/or rely on  collaborators  or licensees or on arrangements  with
others to provide for the  marketing,  distribution,  and sales of its  proposed
products.  There can be no assurance  that the Company will be able to establish
marketing,  distribution and sales  capabilities or make arrangements with third
parties to perform such activities on acceptable terms,  which may result in the
lack of control by the Company over the marketing, distribution and sales of its
proposed  products.  In addition,  there can be no assurance that the Company or
any third party will be  successful in  marketing,  distributing  or selling any
products.  Furthermore,  the Company will compete with many other companies that
currently  have  extensive and  well-funded  marketing,  distribution  and sales
operations. See "Manufacturing and Marketing" in this Item 1.

         Competition.  The biopharmaceutical and radiopharmaceutical  industries
are highly competitive. In the biopharmaceutical industry, there are a number of
companies developing peptide-based drugs, including companies exploring a number
of different  approaches to making  conformationally-constrained  short peptides
for use as therapeutic  drugs. In the  radiopharmaceutical  industry,  there are
several  companies  devoted to development and  commercialization  of monoclonal
antibody-based  products and  peptide-based  products.  The Company is likely to
encounter  significant   competition  with  respect  to  its  proposed  products
currently under development. Many of the Company's competitors which are engaged
in  the   biopharmaceutical   field,   and  in  particular  the  development  of
peptide-based  products,  have substantially greater financial and technological
resources and marketing  capabilities than the Company,  and have  significantly
greater   experience  in  research  and  development.   Many  of  the  Company's
competitors  which  are  engaged  in  the  radiopharmaceutical   field,  and  in
particular the development of antibody- and peptide-based products, have greater
financial  and  technological  resources  and  marketing  capabilities  than the
Company, and have significantly  greater experience in research and development.
Accordingly,  the Company's  competitors may succeed in developing  products and
underlying  technologies  more  rapidly  than  the  Company,  and in  developing
products  that are more  effective  and useful and are less costly than any that
may be  developed  by the  Company,  and may  also be more  successful  than the
Company in  manufacturing  and marketing such products.  Academic  institutions,
hospitals,   governmental   agencies  and  other  public  and  private  research
organizations are also conducting research and seeking patent protection and may
develop competing products or technologies on their own or through collaborative
arrangements.

         The   Company  is  aware  of  at  least  one  company   developing   an
antibody-based product which may compete with LeuTech as to certain indications,
which product is marketed in certain European countries and for which regulatory
approval is pending in the United  States.  The Company is also aware of another
company  developing a peptide-based  product which may also compete with LeuTech
as to  certain  indications.  The  Company  is aware of a  number  of  companies
developing  technologies  relating to the use of peptides as drugs,  including a
variety of different  approaches  to making  conformationally-constrained  short
peptides. See "Competition" in this Item 1.

         The Company is pursuing areas of product  development in which there is
the potential for extensive technological innovation in relatively short periods
of time. Rapid technological  change or developments by others may result in the
Company's proposed products becoming obsolete or non-competitive.

         Dependence  on  Third-Party  Reimbursement.  Successful  sales  of  the
Company's proposed products in the United States and other countries will depend
on the availability of adequate  reimbursement  from third-party  payors such as
governmental entities, managed care organizations and private insurance

                                     Page 22

<PAGE>



plans.  Reimbursement by a third-party  payor may depend on a number of factors,
including  the  payor's  determination  that  use  of  a  product  is  safe  and
efficacious,  neither  experimental nor  investigational,  medically  necessary,
appropriate  for the specific  patient and cost effective.  Since  reimbursement
approval is required from each payor  individually,  seeking such approvals is a
time-consuming   and  costly  process.   Third-party   payors   routinely  limit
reimbursement  coverage and in many instances are exerting  significant pressure
on medical  suppliers to lower their prices.  There is  significant  uncertainty
concerning  third-party  reimbursement for the use of any pharmaceutical product
incorporating  new  technology,  and  there  is no  assurance  that  third-party
reimbursement  will be available for the Company's  proposed  products,  or that
such reimbursement,  if obtained, will be adequate. Less than full reimbursement
by governmental and other  third-party  payors for the Company's  products would
adversely  affect the market  acceptance of these products and would also have a
material  adverse  effect on the  Company.  Further,  health care  reimbursement
systems  vary from  country  to  country,  and there  can be no  assurance  that
third-party  reimbursement  will be made  available for the  Company's  proposed
products under any other reimbursement system. See "Manufacturing and Marketing"
in this Item 1.

         Health Care Reform. The health care industry is undergoing  fundamental
change in the United States as a result of economic,  political  and  regulatory
influences.  There exists a powerful trend toward managed care that is motivated
by a desire to reduce costs and prices of health care.  The Company  anticipates
that the  health  care  industry,  particularly  insurance  companies  and other
third-party  payors,  will  continue to promote  cost  containment  measures and
alternative  health care delivery systems,  and political debate of these issues
will most likely  continue.  The Company cannot  predict which specific  reforms
will be proposed or adopted by industry or government or the precise effect that
such  proposals or adoption  may have on the Company.  There can be no assurance
that health care reform  initiatives  will not have a material adverse effect on
the Company.

         Conducting Business Abroad. To the extent the Company conducts business
outside the United  States,  it may do so through  licenses,  joint  ventures or
other contractual arrangements for the development,  manufacturing and marketing
of its proposed  products.  No  assurance  can be given that the Company will be
able to establish suitable  arrangements,  that the necessary foreign regulatory
approvals  for its  proposed  product  will be  obtained,  that  foreign  patent
coverage will be available or that the development and marketing of its proposed
products through such licenses, joint ventures or other contractual arrangements
will be  successful.  The Company might also have greater  difficulty  obtaining
proprietary  protection for its proposed  products and technologies  outside the
United  States  and  enforcing  its  rights  in  foreign  courts.   Furthermore,
international operations and sales may be limited or disrupted by the imposition
of  governmental  controls  regulation  of  medical  products,   export  license
requirements,  political  instability,  trade restrictions,  changes in tariffs,
exchange  rate   fluctuations   and   difficulties  in  managing   international
operations.

         Risk of  Liability;  Adequacy of  Insurance  Coverage;  Risk of Product
Recall.  The Company's  business may be affected by potential  product liability
risks which are inherent in the testing, manufacturing and marketing of proposed
pharmaceutical  products  to be  developed  by  the  Company.  There  can  be no
assurance  that  product  liability  claims  will not be  asserted  against  the
Company, its collaborators or licensees.  The use of proposed products developed
by the  Company in  clinical  trials and the  subsequent  sale of such  proposed
products is likely to cause the Company to bear all or a portion of those risks.
Such litigation claims could have a material adverse effect on the Company.  The
Company  has  liability  insurance  providing  up  to  $1,000,000  coverage  per
occurrence  and in the aggregate as to certain  clinical  trial risks,  and will
seek   to   obtain   additional   product   liability   insurance   before   the
commercialization of its products.

                                     Page 23

<PAGE>



There can be no  assurance,  however,  that  insurance  will be available to the
Company on  acceptable  terms,  if at all, or that such  coverage  once obtained
would be adequate to protect the Company against future claims or that a medical
malpractice  or other  claim  would not  materially  and  adversely  affect  the
Company.  Furthermore,  there  can be no  assurance  that any  collaborators  or
licensees of the Company will agree to indemnify  the Company,  be  sufficiently
insured or have a net worth  sufficient  to satisfy any such  product  liability
claims.  In addition,  products such as those proposed to be sold by the Company
may be subject  to recall for  unforeseen  reasons.  Such a recall  could have a
material adverse effect on the Company. See "Government Regulation" and "Product
Liability and Insurance" in this Item 1.

         Dependence  on  Key   Management  and  Qualified   Personnel;   Limited
Personnel;  Dependence on Contractors.  The Company is highly dependent upon the
efforts of its  management.  The loss of the  services of one or more members of
management  could impede the achievement of development  objectives.  Due to the
specialized  scientific  nature of the Company's  business,  the Company is also
highly dependent upon its ability to attract and retain qualified scientific and
technical personnel. There is intense competition for qualified personnel in the
areas of the Company's activities and there can be no assurance that the Company
can presently,  or will be able to continue to, attract and retain the qualified
personnel  necessary  for  the  development  of its  existing  business  and its
expansion into areas and activities requiring additional expertise. In addition,
the Company's  intended or possible  growth and expansion  into areas  requiring
additional  skill  and  expertise,  such  as  marketing,   including  sales  and
distribution,  will require the  addition of new  management  personnel  and the
development of additional expertise by existing management  personnel.  The loss
of, or failure to recruit,  scientific,  technical and marketing and  managerial
personnel could have a material adverse effect on the Company.

          The Company  relies,  in  substantial  part,  and for the  foreseeable
future will rely, on certain independent organizations, advisors and consultants
to  provide   certain   services,   including   substantially   all  aspects  of
manufacturing,  regulatory  approval  and clinical  management.  There can be no
assurance  that  the  services  of  independent   organizations,   advisors  and
consultants  will continue to be available to the Company on a timely basis when
needed,  or that the Company could find  qualified  replacements.  The Company's
advisors  and   consultants   generally   sign   agreements   that  provide  for
confidentiality of the Company's proprietary information.  However, there can be
no assurance  that the Company will be able to maintain the  confidentiality  of
the  Company's  technology,  the  dissemination  of which  could have a material
adverse effect on the Company.

         Hazardous  Materials;  Compliance with Environmental  Regulations.  The
Company's  research and  development  involves the  controlled  use of hazardous
materials,  chemicals and various  radioactive  compounds.  Although the Company
believes that its safety procedures for handling and disposing of such materials
comply with the standards  prescribed by federal,  state and local  regulations,
the risk of accidental  contamination  or injury from these materials  cannot be
completely  eliminated.  In the event of such an accident,  the Company could be
held liable for any damages that result and any such liability  could exceed the
resources of the Company. The Company may incur substantial costs to comply with
environmental  regulations if the Company develops  manufacturing  capacity.  In
addition,  there can be no assurance that current or future  environmental laws,
rules,  regulations  or policies will not have a material  adverse effect on the
Company.

          Certain Interlocking Relationships;  Potential Conflicts of  Interest.
Certain of the  directors  of the Company are officers or directors of Paramount
Capital,  Inc. ("Paramount  Capital") or of Paramount Capital  Investments,  LLC
("Paramount Capital Investments"). Paramount Capital Investments is  a  merchant

                                     Page 24

<PAGE>



bank   and   venture   capital   firm    specializing   in   biotechnology   and
biopharmaceutical  companies.  In the regular course of its business,  Paramount
Capital Investments identifies,  evaluates and pursues investment  opportunities
in  biomedical  and   pharmaceutical   products,   technologies  and  companies.
Generally,  Delaware  corporate law requires that any  transactions  between the
Company and any of its affiliates be on terms that,  when taken as a whole,  are
substantially  as favorable to the Company as those then  reasonably  obtainable
from  a  person  who  is  not  an  affiliate  in  an  arms-length   transaction.
Nevertheless,  neither  Paramount  Capital  Investments  nor any other person is
obligated  pursuant to any agreement or  understanding  with the Company to make
any additional products or technologies  available to the Company, and there can
be no assurance,  and purchasers of the Common Stock should not expect, that any
biomedical  or  pharmaceutical  product or  technology  identified  by Paramount
Capital  Investments or any other person in the future will be made available to
the Company. In addition,  certain of the officers,  directors,  consultants and
advisors  to the  Company  may from time to time serve as  officers,  directors,
consultants or advisors to other  biopharmaceutical or biotechnology  companies.
There can be no assurance that such other  companies will not in the future have
interests in conflict with those of the Company. See Item 11 and Item 12.

         Risk of Loss  in  Lawsuit.  The  Company  and one of its  subsidiaries,
Interfilm  Technologies,  Inc.  (collectively,  "IT"),  are the  plaintiffs in a
lawsuit  against Sony  Corporation  of America and certain of its affiliates and
subsidiaries (collectively, "Sony") for breach of contract and breach of duty of
good faith and fair  dealing  (the "IT  Litigation").  In  November  1996,  Sony
asserted two counterclaims in the IT Litigation. The complaint and counterclaims
relate solely to the business activities of the Company prior to the Merger. The
IT  Litigation  is under the  control of and at the  expense of an  unaffiliated
limited liability partnership (the "Partnership"), and is solely for the benefit
of the Company's  pre-Merger  stockholders  as of June 21, 1996.  Based upon the
opinion of the  Company's  counsel of record in the IT  Litigation,  the Company
believes that the counterclaims are without merit.  However,  the Company may be
liable in the event that a  judgment  is  rendered  against  the  Company on the
counterclaims,  and the  assets  of the  Partnership  may not be  sufficient  to
provide full indemnification. See Item 3.



ITEM 2.           DESCRIPTION OF PROPERTY.

         The  Company's  executive  offices are located at 214 Carnegie  Center,
Suite 100,  Princeton,  New Jersey,  where it leases  approximately 4,000 square
feet under a lease which  expires  July 31,  2002.  In March  1997,  the Company
entered into a ten-year lease on  approximately  10,500 square feet for use as a
research  and  development  facility in Edison,  New  Jersey,  with a lease term
commencing  August 1, 1997. The Company had leased  approximately  14,000 square
feet in  Albuquerque,  New Mexico,  which served as the  Company's  research and
development  facility;  in August 1997 the  Albuquerque  facility was closed and
research and development  activities were relocated to the Edison facility.  The
properties the Company leases are in good condition.



ITEM 3.           LEGAL PROCEEDINGS.

         In April 1996, prior to the Merger, IT filed a complaint initiating the
IT Litigation in the Supreme Court of the State of New York, County of New York,
against  Sony for breach of  contract  and breach of duty of good faith and fair
dealing,  seeking  contract  damages of $18  million,  punitive  damages of $100
million and costs. The IT Litigation  relates solely to the business  activities
of the Company prior to the Merger and, pursuant to the Merger,  was included in
certain assets and liabilities of the Company

                                     Page 25

<PAGE>



transferred  to  the  Partnership  solely  for  the  benefit  of  the  Company's
stockholders  as of June 21,  1996.  Accordingly,  the  litigation  is under the
control of and at the expense of the  Partnership,  and the Company will receive
no financial benefit from the litigation, even if the litigation is successfully
concluded.  The assets of the  Partnership,  including  any proceeds from the IT
Litigation,  whether by judgment,  settlement  or  otherwise,  are  available to
indemnify the Company from certain liabilities arising out of the Merger.

         The  causes of action in the IT  Litigation  relate to the  actions  or
inactions of Sony under certain  agreements  entered into between IT and Sony in
April 1993, and as amended in November 1993 and October 1994 (collectively,  the
"Sony-IT  Agreement").  Pursuant to the original terms of the Sony-IT Agreement,
Sony was obligated,  among other things, to develop, produce, market, distribute
and exhibit three Cinematic Games. Subsequently,  at Sony's request, the Sony-IT
Agreement was amended so that Sony's  commitment to produce  Cinematic Games was
reduced to two Cinematic Games in exchange for, among other things, an increased
financial marketing  commitment by Sony. The first Sony-financed  Cinematic Game
was  initially  slated for release in the first half of 1994,  which release was
delayed until  February 1995.  Among other things,  IT alleges that the delay in
the opening of the first Cinematic Game,  which delay IT alleges was primarily a
result  of  Sony's  failure  to abide by the  terms  of the  Sony-IT  Agreement,
seriously harmed IT. Under the terms of the amended Sony-IT Agreement,  Sony was
obligated to begin  principal  photography of the next  Sony-financed  Cinematic
Game by May 15, 1995.

         In November 1996, Sony asserted two counterclaims in the IT Litigation,
generally alleging that the Company's pre-Merger executives misrepresented their
qualifications  and breached the Sony-IT Agreement by not recruiting  sufficient
exhibitors.  The counterclaims  relate solely to the business  activities of the
Company  prior  to the  Merger.  A denial  of the  material  allegations  in the
counterclaims has been filed on behalf of the Company in the IT Litigation.  The
IT Litigation  has been placed on a trial  calendar,  but no trial date has been
set. The  Partnership is obligated to indemnify the Company from certain claims,
including all liabilities and reasonable expenses and costs that the Company may
incur as a result of the IT  Litigation,  and the Company is closely  monitoring
the IT  Litigation.  The  Company  has  incurred  no  out-of-pocket  expenses in
connection with the IT Litigation.  The Company believes that the  Partnership's
assets consist  primarily of the IT Litigation,  certain  intellectual  property
assets and cash assets of approximately  $75,000,  with  liabilities  (primarily
contingent on a recovery in the IT Litigation) totaling approximately  $731,500.
Based upon the opinion of the Company's  counsel of record in the IT Litigation,
the Company  believes that the  counterclaims  are without merit.  However,  the
Company  may be liable in the event  that a judgment  is  rendered  against  the
Company  on the  counterclaims,  and the  assets of the  Partnership  may not be
sufficient to provide full indemnification.

         The Company is involved in various other claims and litigations arising
in the normal course of business,  consisting of actions  commenced  against the
Company prior to the Merger. Management believes that the outcome of such claims
and litigation will not have a material adverse effect on the Company.



ITEM 4.           SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

         No matters  were  submitted  to a vote of security  holders  during the
fourth  quarter of the fiscal year ended June 30, 1997.  However,  on August 21,
1997, and as adjourned to August 25, 1997, at a special meeting of stockholders,
the following matters were adopted by the  stockholders:  (i) the Company's 1996
Stock  Option  Plan,   (ii)  an  amendment  to  the  Company's   Certificate  of
Incorporation  increasing the authorized shares of capital stock from 27,000,000
to 85,000,000 shares, of which 75,000,000 are Common

                                     Page 26

<PAGE>



Stock  and  10,000,000  are  preferred   stock,  and  (iii)  amendments  to  the
Certificate of  Incorporation  authorizing a reverse stock split,  which reverse
split was  subsequently  set by the Board of Directors of the Company at 1-for-4
(the "Reverse  Split").  With respect to approval of the 1996 Stock Option Plan,
there  were  13,590,324  affirmative  votes,  261,058  negative  votes,  195,507
abstentions and 4,796,856 broker  non-votes.  The following table sets forth the
total votes cast with  respect to matters  (ii) and (iii)  above,  as to each of
which there was class voting,  with two classes  entitled to vote,  Common Stock
and Series A Convertible  Preferred  Stock.  The Series A Convertible  Preferred
Stock vote is shown as if converted into Common Stock.

<TABLE>
<CAPTION>

                                SERIES A CONVERTIBLE PREFERRED STOCK                               COMMON STOCK
                          ------------------------------------------------     ---------------------------------------------------
                                            Nega-                   Broker                      Nega-                     Broker
                          Affirmative       tive       Absten-       Non-      Affirmative      tive        Absten-        Non-
Issue                        Votes          Votes       tions       Votes         Votes         Votes        tions        Votes
- -----------------------   -----------     ---------   ---------    -------     -----------    ---------    ---------   -----------
<S>                        <C>            <C>         <C>             <C>    <C>             <C>            <C>        <C>    
(ii) Increase
authorized shares
of capital stock            7,300,365      120,967     120,966         0       6,150,679      122,648        26,125     5,001,995

(iii) Authorize
reverse stock split         7,421,332       20,161     100,805         0      10,950,353      114,965        30,990       205,139
</TABLE>


         The Second  Charter  Amendment  effecting  the  increase in  authorized
shares and  Reverse  Split was filed on  September  5, 1997.  Unless the context
otherwise  requires,  all  references  to the Company's  activities,  results of
operations and financial condition have been adjusted to give retroactive effect
to the Second Charter Amendment.


                                     PART II

ITEM 5.        MARKET FOR COMMON EQUITY AND RELATED STOCKHOLDER MATTERS.

         The Common  Stock has been  quoted on the OTC  Bulletin  Board(R)  (the
"Bulletin  Board")  since  October 1, 1995.  Currently,  the Common Stock trades
under the symbol  "PLTND;"  prior to the Reverse  Split the Common  Stock traded
under the symbol "PLTN." Before July 22, 1996, the Common Stock traded under the
symbol  "IFLM." The Common Stock began trading  publicly on the Nasdaq  National
Market(R)  ("NMS") on October 28, 1993 under the symbol  "IFLM."  Before October
28, 1993,  there was no public  market for the Common  Stock.  On September  30,
1995, the Common Stock was delisted from the NMS for failure to maintain certain
net  tangible  assets  requirements.  The Company has applied to have the Common
Stock quoted on the Nasdaq SmallCap  Market(sm).  There can be no assurance that
the Company will be able to meet the listing requirements of the Nasdaq SmallCap
Market, or if listed,  maintain the criteria for continued listing on the Nasdaq
SmallCap Market.

         The following  table gives the range of high and low bid information on
the Bulletin  Board for the Common Stock for each quarter  since the Merger,  as
obtained from The Nasdaq Stock Market, Inc. The quotations reflect  inter-dealer
prices, without retail mark-up,  mark-down or commission,  and may not represent
actual transactions.

                                     Page 27

<PAGE>




     PERIOD                                 HIGH BID PRICE         LOW BID PRICE
- -------------------------------------       --------------         -------------
June 26 - June 30, 1996 (1)                    $ 20                    $ 16
July 1 - September 30, 1996 (1)                  55                       7
October 1 - December 31, 1996 (1)              11 1/4                   5 3/8
January 1 - March 31, 1997 (1)                  9 1/4                   6 3/8
April 1 - June 30, 1997 (1)                       7                       5
July 1, 1997 - September 23, 1997 (1)           5 4/5                     8
- ------------------------

(1)      The prices in the table have been adjusted to give  retroactive  effect
         to the 1-for-10  reverse  split of the  outstanding  Common Stock which
         became  effective  on July  19,  1996  and  the  Reverse  Split  of the
         outstanding  Common Stock which became  effective on September 5, 1997.
         While  the  Merger  was  effective  June 26,  1996,  no  RhoMed  equity
         securities  were  exchanged  for Common Stock until July 19, 1996,  and
         accordingly  prices  on and prior to July 19,  1996 may not  accurately
         reflect the effects of the Merger.

         Holders.  On September 23, 1997, the approximate number  of holders  of
record of Common Stock was 189.

         Dividend  Policy.  The  Company  has  never  declared  or paid any cash
dividends on the Common Stock. The Company currently intends to retain earnings,
if any, for use in its business and therefore  does not  anticipate  paying cash
dividends in the foreseeable future.  Payment of future dividends,  if any, will
be at the discretion of the Board of Directors after taking into account various
factors, including the Company's financial condition, operating results, current
and  anticipated  cash needs and plans for expansion.  The Company may not pay a
dividend  or make  any  distribution  to  holders  of any  capital  stock of the
Company,  including  Common  Stock,  unless and until the  Company  first pays a
special  dividend or  distribution  of $100 per share to the holders of Series A
Convertible  Preferred  Stock,  and unless holders of two-thirds of the Series A
Convertible Preferred Stock approve the dividend.

         Recent Sales of Unregistered  Securities.  During the period covered by
this Report, except as previously included on a quarterly report on Form 10-QSB,
the Company sold the following  securities  without  registering  the securities
under the  Securities  Act of 1933, as amended (the  "Securities  Act"),  all in
non-underwritten transactions:

         (i) Series A Convertible  Preferred Stock.  The Company sold restricted
shares  of Series A  Convertible  Preferred  Stock to a total of 211  accredited
investors in a private placement for which Paramount Capital served as placement
agent (the "Series A Offering") and claimed  exemption under Section 4(2) of the
Securities Act and Regulation D promulgated thereunder.  The Company offered and
sold the securities solely to accredited  investors (as defined in Regulation D)
and  made no  general  solicitation.  The  certificates  representing  Series  A
Convertible   Preferred  Stock  bear  a  restrictive   legend.   Each  purchaser
represented  to the  Company  that the  purchaser  was  purchasing  the Series A
Convertible  Preferred  Stock for the purchaser's own account for investment and
not with a view toward resale or distribution to others.

                                     Page 28

<PAGE>

<TABLE>
<CAPTION>

                                   Number            Offering                  Cash
        Date of sale             of shares            price               commissions(1)
- ----------------------------- ---------------- --------------------  ------------------------
<S>                             <C>                   <C>                       <C> 

February 21, 1997                       30,630           $3,063,000                  $398,190
April 3, 1997                           76,225           $7,622,500                  $990,925
May 9, 1997                             30,925           $3,092,500                  $402,025
                                     ---------         ------------               -----------
                      TOTALS:          137,780          $13,778,000                $1,791,140
</TABLE>
         -------------------------------------
         (1)      Includes  commission  of  9%  and  a  non-accountable  expense
                  allowance  of  4%.  Does  not  include  the  Preferred   Stock
                  Placement Warrant, described below.

         Each share of Series A Convertible  Preferred Stock is convertible,  at
the option of the  holder  thereof,  into  approximately  20.2  shares of Common
Stock,  calculated  by  dividing  the  stated  value of each  share of  Series A
Convertible  Preferred  Stock  ($100.00) by the conversion  price of $4.96.  The
Series A Convertible  Preferred  Stock has a reset mechanism which provides that
the conversion price is subject to adjustment on May 9, 1998 (the "Reset Date"),
if the  average  closing  bid  price of the  Common  Stock for the  thirty  (30)
consecutive  trading  days  immediately  preceding  the Reset  Date (the  "Reset
Trading  Price") is less than 130% of the then  applicable  conversion  price (a
"Reset  Event").  Upon the  occurrence  of a Reset  Event,  the then  applicable
conversion  price will be reduced to the greater of (i) the Reset  Trading Price
divided  by 1.3 and  (ii)  50% of the  then  applicable  conversion  price.  The
conversion  price is also subject to  adjustment,  under certain  circumstances,
upon the sale or issuance of Common Stock for  consideration per share less than
either (i) the  conversion  price in effect on the date of sale or issuance,  or
(ii)  the  market  price  of the  Common  Stock  as of the  date of the  sale or
issuance.  Upon  the  occurrence  of a  merger,  reorganization,  consolidation,
reclassification, stock dividend or stock split which will result in an increase
or decrease in the number of shares of Common Stock  outstanding  the conversion
price is subject to adjustment.  The Series A Preferred Stock may be mandatorily
converted by the Company if,  commencing  May 9, 1998,  the closing bid price of
the Common Stock has exceeded 200% of the then applicable  conversion  price for
at least  twenty (20) trading  days in any thirty (30)  consecutive  trading day
period ending three (3) days prior to the date of conversion.

         (ii) Preferred Stock Placement Warrant.  The Company issued a Preferred
Stock  Placement  Warrant to purchase an aggregate of 13,778  shares of Series A
Convertible  Preferred Stock to Paramount Capital and/or its designees,  as part
of Paramount  Capital's  compensation  in connection  with the Series A Offering
described  above,  for a nominal  cash  price of  $13.78.  The  Preferred  Stock
Placement  Warrant is exercisable  for a period of five (5) years  commencing in
November  1997, at a price of $110 per share of Series A  Convertible  Preferred
Stock (110% of the offering price of Series A Convertible Preferred Stock in the
Series A Offering),  and  includes a cashless  exercise  provision.  The Company
claimed  exemption  under Section 4(2) of the Securities Act, issued the warrant
to Paramount  Capital and/or its designees as  compensation  and made no general
solicitation.  The Preferred Stock Placement Warrant bears a restrictive  legend
generally restricting transfer.

         (iii)  Common Stock issued on exercise of employee  stock  options.  On
April 11,  1997,  the Company sold 17,969  restricted  shares of Common Stock to
Edward J.  Quilty  (the  Company's  Chairman  of the  Board and Chief  Executive
Officer) upon partial  exercise of an option  granted to Mr. Quilty  pursuant to
his employment  agreement.  The Company claimed  exemption under Section 4(2) of
the Securities Act, as a

                                     Page 29

<PAGE>



transaction not involving any public  offering.  The stock subject to the option
is offered only to Mr. Quilty,  at approximately  $.217 per share. The option is
not  transferable  during Mr.  Quilty's  lifetime and the Common Stock issued on
exercise of the option is restricted.  The certificates  representing the Common
Stock  issued on exercise of the option bear  restrictive  legends.  The Company
sold the Common Stock directly to Mr. Quilty with no discount or commission.

         (iv) Common Stock issued to pay interest obligation. On April 30, 1997,
the Company sold 63,910  restricted  shares of Common Stock to Bioquest  Venture
Leasing Partnership L.P., the designee of Aberlyn, a creditor of the Company, as
payment in full of $303,171 of accrued  interest  which the Company owed Aberlyn
under a financing arrangement.  The Company claimed exemption under Section 4(2)
of the Securities Act, for a transaction not involving any public offering. This
was a one-time  transaction  negotiated at arm's length  between the Company and
its  largest  creditor.  The  Common  Stock  issued as payment  of  interest  is
restricted and the certificate representing the Common Stock bears a restrictive
legend.  Aberlyn  represented  to the Company that Aberlyn and its designee were
accredited  investors  (as  defined  in  Regulation  D) and that  Aberlyn or its
designee was  acquiring  the stock for its own account and not with a view to or
for sale in connection with any distribution of the Common Stock in violation of
the  Securities  Act. The Company  sold the Common  Stock  directly to Aberlyn's
designee with no commission.

         Registration Statement. Pursuant to the terms of the Series A Offering,
the Company filed a  registration  statement  with the  Securities  and Exchange
Commission  on Form SB-2 on August 13,  1997,  relating to  2,777,822  shares of
Common Stock issuable on conversion of the Series A Convertible  Preferred Stock
and  277,782  shares of Common  Stock  issuable  on  conversion  of the Series A
Convertible  Preferred  Stock  obtainable  upon exercise of the Preferred  Stock
Placement  Warrant.  This registration  statement also includes 63,910 shares of
Common  Stock  issued to Bioquest  Venture  Leasing  Partnership  L.P. to pay an
interest  obligation and approximately  447,026 shares of Common Stock issued or
issuable upon exercise of certain outstanding warrants. See Item 12 and Notes to
Consolidated Financial Statements.



ITEM 6.           MANAGEMENT'S DISCUSSION  AND  ANALYSIS  OF FINANCIAL CONDITION
                  AND RESULTS OF OPERATIONS.

GENERAL

         The following  discussion  and analysis  should be read in  conjunction
with the  consolidated  financial  statements and notes thereto filed as part of
this Report.

RESULTS OF OPERATIONS

YEAR ENDED JUNE 30, 1997 COMPARED TO THE YEAR ENDED JUNE 30, 1996

         Grants and contracts - During the year ended June 30, 1997, the Company
had four active Phase I SBIR Research Grants, totaling $394,970,  under the SBIR
program with the NIH. Grant and contract  revenue from these grants was $350,173
during the year ended June 30,  1997,  compared  to no revenue  from  grants and
contracts during the year ended June 30, 1996.

         License fees and royalties - In December 1996, the Company entered into
the Option  Agreement  with Nihon,  pursuant to which the Company  received,  in
January 1997, an initial payment of $1,000,000 before Japanese withholding taxes
of $100,000 (the "Initial  Payment").  The Company has accounted for the Initial
Payment by recognizing  license fee revenue of $350,000 and deferred license fee
revenue of

                                     Page 30

<PAGE>



$550,000.  The deferred license fee revenue will be recognized as revenue when a
license agreement is consummated.  In the event that the parties cannot agree on
terms of a  license  agreement,  then the  Company  could be  required  to repay
$550,000 of the Initial  Payment to Nihon.  There were no revenues  from license
fees or royalties during the year ended June 30, 1996.

         Sales - During the year ended June 30, 1997,  the Company  discontinued
sales of its RhoChek  product due to  insufficient  sales.  Total  revenues from
sales during the year ended June 30, 1997, were $22,184, compared to $27,517 for
the year ended June 30, 1996.

         Research and development  expenses - Research and development  expenses
increased to  $3,409,983  for the year ended June 30, 1997 from $953,730 for the
year ended June 30, 1996. The increase is attributable to expansion in the scale
of the Company's research and development  operations,  which expansion followed
completion of an equity  offering  immediately  prior to the Merger.  During the
year ended June 30, 1997, the Company  increased the  manufacturing  development
scale-up expenses for LeuTech by approximately $779,000,  incurred approximately
$200,000 in  increased  regulatory  consulting  related to LeuTech,  incurred an
increase  in  license  fees paid of  $170,000,  incurred  laboratory  relocation
expenses  of  $142,000,  and had its first  full year  with two  executive  vice
presidents  with  responsibilities  for  research  and  development  at a salary
expense of approximately  $300,000. The Company expects research and development
expenses  to  continue  to  increase  in  future  years as the  Company  expands
manufacturing  development  efforts and initiates clinical trials on LeuTech and
significantly expands its efforts to develop the MIDAS technology, including the
hiring of scientists and the acquisition of equipment and supplies.

         General  and  administrative  expenses  -  General  and  administrative
expenses  increased  to  $2,533,883  for the  year  ended  June  30,  1997  from
$1,633,598 for the year ended June 30, 1996. The increase is  attributable  to a
full year of expenses in the year ended June 30, 1997  related  primarily to the
hiring of certain key executives, the leasing of executive offices in New Jersey
and increased travel, legal and consulting expenses.  General and administrative
expenses were also affected by amortization, totaling approximately $395,000, of
the value of options and warrants issued to consultants and the value of options
granted at exercise  prices below the then current market price of the Company's
Common Stock. In addition,  the Company has been actively  searching for certain
products  and  technologies  to  license  or  acquire,  and  incurred  costs  in
evaluating these products and  technologies  during the year ended June 30, 1997
amounting  to  approximately  $187,000,  which has been  included in general and
administrative  expenses.  General and  administrative  expenses are expected to
remain consistent with the current levels for the 1998 fiscal year.

         Interest  income - Interest  income  increased to $296,009 for the year
ended June 30, 1997 from $10,515 for the year ended June 30, 1996.  The interest
income is primarily  the result of interest on the net proceeds from the Company
pre-Merger equity offering and the Series A Offering.

         Interest expense - Interest expense  decreased to $374,664 for the year
ended June 30, 1997 from $494,814 for the year ended June 30, 1996. The decrease
is mainly due to the repayment by the Company of certain  pre-Merger  notes, the
principal  amount of which was  $1,000,000,  in August  and  September  of 1996.
Interest  expense is  expected  to remain at current  levels for the 1998 fiscal
year.

         Net loss - Net loss increased to $5,300,164 for the year ended June 30,
1997 from $4,247,664 for the year ended June 30, 1996.

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<PAGE>



TEN MONTH PERIOD ENDED JUNE 30, 1996 COMPARED TO TEN MONTH PERIOD ENDED JUNE 30,
1995.

         License fees and royalties - License fees and  royalties  were zero for
the ten months ended June 30, 1996,  compared to $64,296 for the prior ten month
period.  During the ten months ended June 30,  1996,  there were no royalties on
product sales or new license agreements.

         Sales -  Sales  of  RhoChek,  the  sole  product  sold by the  Company,
decreased to $24,457 in the ten months ended June 30, 1996,  from $30,546 in the
prior ten month period.

         Research and development  expenses - Research and development  expenses
increased  by $391,983 to $869,896  for the ten months  ended June 30, 1996 from
$477,913 in the ten months ended June 30, 1995.  The majority of the increase is
attributable  to  development  of LeuTech,  including  increased  consulting and
manufacturing scale-up expenses.

         General  and  administrative  expenses  -  General  and  administrative
expenses  increased  to  $1,366,343  in the ten months  ended June 30, 1996 from
$598,560 for the ten months ended June 30, 1995. The majority of the increase is
due to the hiring of a Chairman of the Board and Chief Executive  Officer and of
a Chief Financial Officer, the leasing of general and administrative  offices in
New Jersey, and increased travel and consulting expenses.

         Other  expenses - Other  expenses  increased to $1,142,963  for the ten
months ended June 30, 1996 from $305,615 for the ten months ended June 30, 1995.
The increase is attributable primarily to increased interest expense, commission
and fees paid in connection  with the  Company's  pre-Merger  debt  offerings of
$168,970 and costs and fees associated with the Merger of $525,000.

         Net loss - Net loss  increased  to  $3,897,879  in the ten months ended
June 30, 1996, compared to $1,287,246 in the prior ten month period.

LIQUIDITY AND CAPITAL RESOURCES

         Since its inception, the Company has incurred net operating losses and,
as of June 30, 1997, had an accumulated deficit of $13,433,102.  The Company has
financed its net operating  losses through June 30, 1997 by a series of debt and
equity  financings.  At June 30, 1997, the Company had cash and cash equivalents
of $12,806,717.

         For the year ended June 30, 1997,  the net increase in cash amounted to
$6,015,417. Net cash used for operating activities was $4,126,684, net cash used
for  investing  activities  was  $279,705,  and net cash  provided by  financing
activities was $10,421,806.

         On December 2, 1996,  the Company  commenced the Series A Offering at a
price of $100,000  per unit,  each unit  consisting  of 1,000 shares of Series A
Convertible  Preferred  Stock.  The final  closing on the Series A Offering  was
effective as of May 9, 1997,  with the Company having sold an aggregate total of
137.78 units,  representing  137,780  shares of Series A  Convertible  Preferred
Stock,  for net  proceeds to the  Company of  approximately  $11,637,000,  after
deducting commission and other expenses of the Series A Offering.

         Pursuant  to the Option  Agreement,  Nihon can  maintain  its option to
license  certain  products  based on the MIDAS  technology  provided Nihon makes
certain milestone payments based on progress in product  development.  Nihon may
exercise its right to negotiate a license  agreement at any time upon notice and
payment of  additional  monies to the  Company.  In the event  that the  parties
cannot agree on terms of a license agreement, then the Company could be required
to repay $550,000 to Nihon. There can be no

                                     Page 32

<PAGE>



assurance  that the Company and Nihon will ever enter into a definitive  license
agreement, that additional payments provided for in the Option Agreement will be
made, or that the strategic  alliance  between the Company and Nihon will result
in the development or commercialization of any product.

         Pursuant to certain license agreements relating to LeuTech, the Company
is obligated  to make minimum  payments of $100,000 per year in the fiscal years
ending June 30, 1998 and 1999,  and  $125,000 in the fiscal year ending June 30,
2000.

         Pursuant to the terms of certain  notes  payable to  stockholders,  the
principal of which  aggregates  $80,000,  repayment of principal and interest is
required in the second quarter of the fiscal year ending June 30, 1998.

         Commencing  June 1997,  the  Company's  monthly  payments on  long-term
financing  provided by Aberlyn  increased  to $91,695,  representing  payment of
current  interest and  principal.  The final monthly  payment is scheduled to be
made in May 1999.

         In March 1997,  the Company  entered into a ten-year  lease on research
and development facilities in Edison, New Jersey, with the lease term commencing
August 1, 1997.  Minimum  future  lease  payments  escalate  from  approximately
$116,000  per year to $200,000  per year after the fifth year of the lease term.
The lease will expire in fiscal year 2007. The Company anticipates that the cost
of tenant improvements,  net of the landlord's contribution,  and acquisition of
laboratory equipment will amount to approximately $1,600,000.

         Effective August 1, 1997, the Company entered into a five-year lease on
administrative  offices in Princeton,  New Jersey. Minimum future lease payments
are approximately $97,000 per year.

         The Company  believes that it has sufficient cash and cash  equivalents
to fund the Company's  projected debt obligations and fund projected  operations
for fiscal year 1998.

         The Company expects to continue actively searching for certain products
and  technologies  to  license  or  acquire  in the  future.  If the  Company is
successful in identifying a product or technology for  acquisition,  substantial
funds  may be  required  for such  acquisition  and  subsequent  development  or
commercialization.  To date,  the Company has not completed an  acquisition  and
there  can be no  assurance  that any  acquisition  will be  consummated  in the
future.

         The Company anticipates  incurring  additional losses over at least the
next  several  years,  and such  losses are  expected to increase as the Company
expands its research and development activities relating to its MIDAS technology
and its direct radiolabeling technology. To achieve profitability,  the Company,
alone or with others,  must  successfully  develop its technologies and proposed
products,  conduct  pre-clinical  studies and clinical  trials,  obtain required
regulatory  approvals and successfully  manufacture and market such technologies
and  proposed  products.  The time  required  to reach  profitability  is highly
uncertain,  and  there  can be no  assurance  that the  Company  will be able to
achieve profitability on a sustained basis, if at all.



ITEM 7.           FINANCIAL STATEMENTS.

         The Company's  consolidated  financial statements appear following Item
13 of this Report.



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<PAGE>



ITEM 8.           CHANGES IN AND  DISAGREEMENTS  WITH  ACCOUNTANTS ON ACCOUNTING
                  AND FINANCIAL DISCLOSURE.

         As of July 9, 1996,  in connection  with the Merger,  Deloitte & Touche
LLP, the  Company's  independent  accountant  which was engaged as the principal
accountant to audit the  Company's  financial  statements,  was  dismissed.  The
Company,  after  consultation  with Arthur Andersen LLP, engaged Arthur Andersen
LLP as of July 9,  1996 as the  principal  accountant  to  audit  the  Company's
financial  statements.  Arthur  Andersen  LLP  served  as  RhoMed's  independent
accountant prior to the Merger.

         RhoMed,  prior to the Merger,  consulted  Arthur Andersen LLP regarding
the  application of accounting  principles to the proposed  Merger.  The primary
issue that was the subject of such consultations was the characterization of the
proposed  Merger for  accounting  purposes.  RhoMed was orally advised by Arthur
Andersen  LLP that the Merger would be treated as a  recapitalization  of RhoMed
with RhoMed as the acquirer (reverse acquisition),  and that the proposed Merger
would not constitute a business  combination.  The Company's former  accountant,
Deloitte & Touche LLP, was not consulted by the Company regarding such issue.

         The  Company's  decision  to change  accountants  was  recommended  and
approved by the Company's Board of Directors subsequent to the Merger based upon
the Company's  need for one  independent  accountant to be  responsible  for the
financial  statements of the Company  following the Merger.  During  Interfilm's
fiscal  years  ended  December  31, 1995 and 1994,  there were no  disagreements
between the Company and Deloitte & Touche LLP, the Company's former  independent
accountant,  on any matter of  accounting  principles  or  practices,  financial
statement  disclosure,   or  auditing  scope  or  procedure.   Further,   during
Interfilm's  fiscal  years  ended  December  31,  1995 and  1994,  respectively,
Deloitte  &  Touche  LLP's  opinion  with  respect  to the  Company's  financial
statements  was  qualified  as to the  Company's  ability to continue as a going
concern.



                                    PART III

ITEM 9.           DIRECTORS, EXECUTIVE OFFICERS, PROMOTERS AND CONTROL  PERSONS;
                  COMPLIANCE WITH SECTION 16(A) OF THE EXCHANGE ACT.

EXECUTIVE OFFICERS AND DIRECTORS

The following table sets forth the name and positions of the executive  officers
and directors of the Company:


Name                       Age       Position with the Company
- -----------------------   -----      ----------------------------------------
Edward J. Quilty (1)        46       Chairman of the Board, President, Chief
                                     Executive Officer and Director
Carl Spana, Ph.D.           35       Executive Vice President, Chief Technology
                                     Officer and Director
Charles Putnam              45       Executive Vice President
John J. McDonough           33       Vice President and Chief Financial Officer


                                     Page 34

<PAGE>



Name                              Age       Position with the Company
- -----------------------          -----      ---------------------------------
Michael S. Weiss (2)               31       Director
James T. O'Brien (2)               58       Director
John K.A. Prendergast, Ph.D. (1)   43       Director

- ------------------------------------
(1)      Member of the Compensation Committee.   Mr. Quilty, as President of the
         Company, is a member ex officio of the Compensation Committee.

(2)      Member of the Audit Committee.


     EDWARD J. QUILTY has been Chairman of the Board, President, Chief Executive
Officer and a director of the Company since June 25, 1996, the effective date of
the Merger,  and has been Chief Executive Officer and a director of RhoMed since
November 1995.  From July 1994 through  November 1995, Mr. Quilty was President,
Chief Executive Officer and a director of MedChem Products, Inc. ("MedChem"),  a
publicly traded medical device company,  which in September 1995 was merged into
C.R.  Bard,  Inc.  From  March 1992  through  July 1994,  Mr.  Quilty  served as
President and Chief  Executive  Officer of Life Medical  Sciences,  Inc.  ("Life
Medical"),  a publicly traded biotechnology  company.  From January 1987 through
October 1991,  Mr. Quilty  served as Executive  Vice  President of McGaw Inc., a
publicly traded pharmaceutical company. Mr. Quilty is also Chairman of the Board
and a director  of Derma  Sciences,  Inc.,  a  publicly  traded  medical  device
company.  Mr. Quilty received his M.B.A.  from Ohio University,  and a B.S. from
Southwest Missouri State University.

     CARL SPANA,  Ph.D., has been a director of the Company since June 25, 1996,
the effective  date of the Merger,  and has been a director of RhoMed since July
1995.  Since June 1996,  Dr. Spana has served as Executive  Vice  President  and
Chief Technology Officer of the Company and RhoMed. From June 1993 to June 1996,
Dr. Spana was Vice President of Paramount Capital  Investments,  a biotechnology
and  biopharmaceutical  merchant  banking  firm,  and of The  Castle  Group Ltd.
("Castle  Group"),   a  medical  venture  capital  firm.  At  Paramount  Capital
Investments  and at Castle Group,  Dr. Spana was  responsible  for  discovering,
evaluating, and commercializing  biotechnologies.  Through his work at Paramount
Capital  Investments and Castle Group, Dr. Spana co-founded and acquired several
private  biotechnology  firms.  From July  1991 to June  1993,  Dr.  Spana was a
Research  Associate at Bristol-Myers  Squibb,  a publicly traded  pharmaceutical
company,  where  he  was  involved  in  scientific  research  in  the  field  of
immunology.  Dr.  Spana  is a  director  of and was  Interim  President  of AVAX
Technologies,  Inc. ("AVAX"),  a publicly traded medical technology company. Dr.
Spana received his Ph.D. in Molecular Biology from The Johns Hopkins  University
and a B.S. in Biochemistry from Rutgers University.

     CHARLES  PUTNAM has been Executive Vice President of the Company since June
25, 1996, the effective date of the Merger,  and is responsible  for operations,
product  development and regulatory and clinical affairs.  From July 1994 to May
1996,  Mr. Putnam was Executive Vice  President,  Research and  Development,  of
MedChem.  At  MedChem,  Mr.  Putnam was  responsible  for  product  development,
regulatory  affairs,  clinical research and quality control.  From March 1993 to
July  1994,  Mr.  Putnam was Vice  President  of  Operations  and  Research  and
Development of Life Medical, where he was responsible

                                     Page 35

<PAGE>



for all aspects of manufacturing, product development and regulatory affairs for
the company's commercial product line. From March 1983 to March 1993, Mr. Putnam
was  employed  by  American  Cyanamid  Corporation  in a variety  of  positions,
including Director of Device Development.

     JOHN J.  McDONOUGH has been Vice President and Chief  Financial  Officer of
the Company since June 25, 1996, the effective date of the Merger,  and has been
Vice President and Chief Financial Officer of RhoMed since December,  1995. From
January 1992 through  December  1995,  Mr.  McDonough was employed by MedChem in
various  positions,  his final position being Vice President and Chief Financial
Officer.  Previously,  Mr.  McDonough was a manager with KPMG Peat Marwick.  Mr.
McDonough  received  his B.S.  in  Accountancy  from  Bentley  College  and is a
candidate  for an M.B.A.  from Harvard  Business  School due to graduate in June
1998.

     MICHAEL S. WEISS has been a director  of the Company  since June 25,  1996,
the effective  date of the Merger,  and has been a director of RhoMed since July
1995. Since November 1993, Mr. Weiss has been Associate General Counsel and then
General Counsel of Paramount Capital Investments and Senior Managing Director of
Paramount Capital. Prior to that Mr. Weiss was an attorney with Cravath,  Swaine
&  Moore.   Mr.  Weiss  also  serves  on  the  Board  of  Directors  of  Pacific
Pharmaceuticals,  Inc.,  AVAX,  as Secretary of Atlantic  Pharmaceuticals,  Inc.
("Atlantic Pharmaceuticals"), and as Vice Chairman of the Board and on the Board
of Directors of Genta Incorporated and as Chairman of the Board and on the Board
of Directors of Procept Inc., all publicly traded medical technology  companies.
Additionally,  Mr.  Weiss  is a member  of the  board of  directors  of  several
privately  held  biopharmaceutical  companies.  Mr. Weiss received his J.D. from
Columbia  University  School  of Law  and a  B.S.  in  Finance  from  The  State
University of New York at Albany.

     JAMES T.  O'BRIEN has been a director of the Company  since August 1, 1996.
Since  November  1991,  Mr.  O'Brien  has been  Chairman  of the Board of Access
Corporation, a provider of employment software and information. Since July 1996,
Mr. O'Brien has been President and Chief Executive  Officer of O'Brien Marketing
and Communications, an advertising and communications company. From 1989 to 1991
Mr. O'Brien was President and Chief Operating Officer of Elan Corporation,  PLC,
a publicly  traded  pharmaceutical  company.  From 1986 to 1989, Mr. O'Brien was
President and Chief Executive Officer of O'Brien Pharmaceuticals,  Inc. Prior to
this,  Mr.  O'Brien held various  management  positions  with Revlon Health Care
Group,  including  President of USV Laboratories  and the Armour  Pharmaceutical
Company; Lederle Laboratories; and Sandoz Pharmaceuticals, Inc. Mr. O'Brien is a
director of Carrington Laboratories,  Inc., a publicly traded pharmaceutical and
medical devices company, and Theratech,  Inc., a publicly traded  pharmaceutical
and drug delivery company.

     JOHN K.A.  PRENDERGAST,  Ph.D.  has been a director  of the  Company  since
August 28, 1996. Dr.  Prendergast has served as a Managing Director of Paramount
Capital  Investments  and as a Managing  Director of Castle Group since  October
1991. Dr. Prendergast is a co-founder and director of Avigen, Inc. ("Avigen"), a
medical technology  company,  and, from December 1992 to March 1996, served as a
Vice President and the Treasurer of Avigen, Inc. Dr. Prendergast is a co-founder
and  director of  Xenometrix,  Inc.,  AVAX,  and Atlantic  Pharmaceuticals,  all
publicly traded medical technology companies. Dr. Prendergast received M.Sc. and
Ph.D.  degrees from the University of New South Wales,  Sydney,  Australia and a
C.S.S. in Administration and Management from Harvard University.

         There  are no  family  relationships  between  directors  or  executive
officers.

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<PAGE>



         All directors hold office until the next annual meeting of stockholders
of the Company  and until  their  successors  have been  elected and  qualified.
Officers serve at the discretion of the Board of Directors.

         Certain of the officers and directors of the Company  currently do, and
may from time to time in the future,  serve as officers  or  directors  of other
biopharmaceutical or biotechnical companies. There can be no assurance that such
other  companies will not in the future have interests in conflict with those of
the Company.  See "Important  Factors  Regarding  Forward-Looking  Statements --
Certain Interlocking Relationships; Potential Conflicts of Interest" in Item 1.

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

          Edward J. Quilty  failed to timely report a transaction  on Form 4 for
the month of April 1997 and John K.A.  Prendergast  failed to timely  report his
initial  ownership  on Form 3 for the month of August 1996.  Mr.  Quilty and Mr.
Prendergast each subsequently  reported the required  information on Forms 5 for
the fiscal year ended June 30, 1997. The Aries Trust failed to timely report its
initial  ownership  on  Form 3 for the  month  of July  1996,  but  subsequently
reported the required information on a Form 5 for the fiscal year ended June 30,
1997. The Company knows of no other failure to file a required form.



ITEM 10.          EXECUTIVE COMPENSATION.

         The following table sets forth compensation paid to the Company's Chief
Executive  Officer and the other  named  executive  officers  for the last three
fiscal years.  See note (1) to the  following  table,  concerning  the change in
fiscal  year end.  With  respect  to the  persons  and  periods  covered  in the
following  table,  the  Company  made  no  restricted  stock  awards  and had no
long-term incentive plan payouts.

                                     Page 37

<PAGE>

<TABLE>
<CAPTION>
                                                    SUMMARY COMPENSATION TABLE

                                              Annual Compensation                                    Long Term Compensation
                                -------------------------------------------------------       ------------------------------------
                                                                                                     Awards
                                                                                 Other        -------------------  
                                                                                 Annual           Securities         All other
                                                                                Compen-           Underlying          Compen-
Name and                                        Salary           Bonus           sation            Options/            sation
Principal Position             Year(1)            ($)             ($)             ($)             SARs (#)(2)           ($)
- ------------------             -------          ------           -----          -------           -----------        ---------
<S>                            <C>            <C>               <C>             <C>                <C>               <C>
Edward J. Quilty,                1997         $301,064             --              --                240,074(4)             --
Chief Executive                  1996         $184,794             --              --                178,073                --
Officer(3)                       1995              N/A            N/A             N/A                    N/A                --

Carl Spana, Ph.D.,               1997         $150,000             --              --                 41,766                --
Executive Vice                   1996           $3,462             --              --                 74,196           $25,000(6)
President(5)                     1995              N/A            N/A             N/A                    N/A               N/A

Charles L. Putnam,               1997         $150,000             --              --                 41,766                --
Executive Vice                   1996           $9,539             --              --                 74,196                --
President(7)                     1995             N/A             N/A             N/A                    N/A               N/A
</TABLE>

- --------------------------------
(1)      The  Company's  fiscal  year  ends on June 30.  Due to a change  in the
         Company's  fiscal year end, unless  otherwise  specified  herein fiscal
         year 1996 covers the ten-month transition period from September 1, 1995
         to June 30,  1996.  Fiscal year 1995 ended  August 31,  1995  (RhoMed's
         former fiscal year end). All references to compensation before June 25,
         1996 (the Merger date) relate to compensation paid or issued by RhoMed.

(2)      The security  underlying  all options is Common  Stock.  All amounts of
         Common  Stock in the table have been  adjusted  to reflect  the Reverse
         Split.

(3)      Mr. Quilty became  an employee and Chief Executive Officer of RhoMed on
         November 16, 1995 and became Chief Executive Officer of the Company  on
         June 25, 1996.

(4)      Includes an  anti-dilution  option to purchase  70,257 shares of Common
         Stock at $.20 per share granted on September 27, 1996,  pursuant to the
         terms  of Mr.  Quilty's  employment  agreement  with the  Company.  See
         "Employment Agreements" below. The September 27, 1996 option replaced a
         canceled  option  to  purchase  the same  number of shares at $5.42 per
         share,  originally  granted by RhoMed on June 21, 1996 and  included in
         the 1996 total. The $5.42 per share price of the June

                                     Page 38

<PAGE>



         21, 1996 option was not in  accordance  with the terms of Mr.  Quilty's
         employment  agreement,  so the Board of Directors replaced the June 21,
         1996 option  with the  correctly  priced  September  27,  1996  option.
         Excluding that  replacement  option,  the options granted during fiscal
         1997 were to purchase a total of 169,817 shares.

(5)      Dr.  Spana  became  an  employee  of  RhoMed  on June  15,  1996 and an
         Executive  Vice  President  of the  Company  on June 25,  1996.  Before
         becoming an officer of the Company, he was a consultant to RhoMed.

(6)      Consists of consulting fees paid by RhoMed.

(7)      Mr.  Putnam  became  an  employee  of  RhoMed  on  June  3, 1996 and an
         Executive Vice President of the Company on June 25, 1996.



                      OPTION/SAR GRANTS IN LAST FISCAL YEAR

         The  following  table  sets  forth  the  options  granted  to the named
executive  officers  during the fiscal  year ended June 30,  1997.  The  Company
granted no stock appreciation rights ("SARs").

<TABLE>
<CAPTION>
                                                                                       Market Price
                                Number of            % of Total                         as Reported
                                Securities          Options/SARs        Exercise        on Bulletin
                                Underlying           Granted to          or Base         Board on
           Name                Options/SARs           Employees           Price           Date of          Expiration
                               Granted (#)         in Fiscal Year        ($/Sh)            Grant              Date
                               ------------        --------------       --------       ------------        ----------
<S>                             <C>                    <C>              <C>               <C>             <C>
Edward J. Quilty                70,257(1)              17.77%             $0.20(1)        $10.50              none
                                30,000(2)               7.59%             $7.50            $7.50            12-12-06
                                82,542(3)              20.88%             $0.20(3)         $6.00              none
                                57,275(4)              14.49%             $4.96(6)         $6.00             6-2-07

Carl Spana, Ph.D.               15,000(2)               3.79%             $8.00            $8.00             1-3-07
                                26,766(5)               6.77%             $4.96(6)         $6.00             6-2-07

Charles L. Putnam               15,000(2)               3.79%             $8.00            $8.00             1-3-07
                                26,766(5)               6.77%             $4.96(6)         $6.00             6-2-07
</TABLE>

- --------------------------------
(1)      Anti-dilution  option  granted  pursuant  to the  Company's  employment
         agreement with Mr. Quilty. During the employment term, the option vests
         in 29  equal  monthly  installments  on the  16th  of each  month.  See
         "Employment Agreements" in this Item 10.

(2)      Granted under the 1996 Stock Option Plan and immediately exercisable.

                                     Page 39

<PAGE>



(3)      Anti-dilution  option  granted  pursuant  to the  Company's  employment
         agreement with Mr. Quilty. During the employment term, the option vests
         in 18 equal monthly  installments  on the 16th of each month  following
         the date of grant. See "Employment Agreements" in this Item 10.

(4)      Vests in 17 equal monthly installments on the 16th of each month  after
         July 1, 1997.

(5)      Vests in three equal installments, on July 1, 1997;  July 1, 1998;  and
         June 21, 1999.

(6)      Non-plan option.



               AGGREGATED OPTION/SAR EXERCISES IN LAST FISCAL YEAR
                          AND FY-END OPTION/SAR VALUES

         The  following  table  sets  forth  each  option  exercise  by a  named
executive  officer  during the fiscal year ended June 30,  1997.  Only Edward J.
Quilty  exercised  any  options.  The Company has no  outstanding  SARs.  Fiscal
year-end values are based on a last reported sale price for the Common Stock, as
reported on the Bulletin Board on June 30, 1997, of $6.125 per share.

<TABLE>
<CAPTION>

                                                                           Number of
                                                                           Securities                      Value of
                                                                           Underlying                     Unexercised
                                                                          Unexercised                    In-the-Money
                                   Shares                               Options/SARs at                  Options/SARs
                                  Acquired           Value                 FY-End (#)                    at FY-End ($)
                                on Exercise        Realized               Exercisable/                   Exercisable/
Name                                (#)             ($) (1)              Unexercisable                   Unexercisable
- -------------------             -----------        ---------             --------------               -------------------
<S>                                <C>             <C>                   <C>                          <C>             
Edward J. Quilty                   47,918          $310,065              72,642/227,331               $252,504/$1,073,451
Carl Spana, Ph.D.                    0                --                 64,465/51,499                  $33,884/$48,125
Charles L. Putnam                    0                --                 39,732/76,231                  $16,942/$65,066
</TABLE>

- --------------------------------

(1)      Value  realized is the closing market price of the stock on the date of
         exercise  less the  option  price,  multiplied  by the number of shares
         acquired on exercise.

COMPENSATION OF DIRECTORS

         Pursuant to the 1996 Stock Option Plan each director of the Company who
is not an employee of the Company or of a parent or subsidiary of the Company (a
"Non-Employee  Director") will be granted,  at the first meeting of the Board of
Directors  following each annual meeting of the stockholders of the Company,  an
option to purchase  2,500 shares of Common Stock at a per share  exercise  price
equal to the fair market  value of a share of Common Stock on the date of grant,
which options are to vest as to 25% per of the option  granted during each year,
starting one year after the date of grant (a  "Non-Employee  Director's  Formula
Option").  Any  Non-Employee  Director  who is elected to the Board of Directors
after  August 28, 1996 and before the annual  stockholders'  meeting in any year
will also be granted a  Non-Employee  Director's  Formula  Option to  purchase a
pro-rata  portion of 2,500  shares  equal to the portion of a year  (measured in
full calendar months)  remaining until the next scheduled  annual  stockholders'
meeting.  All Non-Employee  Directors serving on the date the Board of Directors
adopted the 1996 Stock

                                     Page 40

<PAGE>



Option Plan (Richard J. Murphy,  who resigned as a director effective August 26,
1997, James T. O'Brien, John K.A. Prendergast and Michael S. Weiss) were granted
initial  Non-Employee  Director's  Formula  Options to purchase  5,000 shares of
Common  Stock at an  exercise  price of $5.44 per share  with the same  exercise
price and vesting conditions as regular Non-Employee Director's Formula Options.

         Non-Employee  Directors are paid $12,000 per year,  plus expenses,  for
services as a  director.  In lieu of the  $12,000  per year,  each  Non-Employee
Director  may,  and Mr.  O'Brien  and Mr.  Weiss  have,  elected  to  receive  a
non-incentive  stock  option  pursuant to the 1996 Stock Option Plan to purchase
that number of shares which would be purchasable, at the then fair market value,
by a sum equal to twice the then  accrued  compensation.  Such  options  will be
granted at a per share  exercise price equal to the fair market value of a share
of Common Stock on the date of grant,  will be immediately  exercisable and will
expire ten (10) years from the date of grant. The Board of Directors  previously
agreed  that in  lieu  of  $4,000  which  was  due to  each of the  Non-Employee
Directors  as of  December  1996,  such  directors  could  elect  to  receive  a
non-incentive  stock  option  pursuant to the 1996 Stock Option Plan to purchase
1,066 shares of Common Stock at an exercise price of $7.50 per share,  which was
the fair market value per share on the date of grant.  Mr.  Murphy,  Mr. O'Brien
and Mr. Weiss were each granted such options, which are immediately  exercisable
and expire ten (10) years  from the date of grant.  Employee  directors  are not
separately  compensated  for  services as a  director,  but are  reimbursed  for
expenses incurred in performing their duties as directors,  including  attending
all meetings of the Board of Directors and any committees thereof.  Service as a
director is a condition of Edward J.  Quilty's  employment  agreement,  but such
service is not separately compensated.  See "Employment Agreements" in this Item
10.

         In July 1996,  the Company  paid $36,000 to Buck A.  Rhodes,  Ph.D.,  a
former  director  of the  Company  and RhoMed,  as  severance  compensation  for
resigning from the board of RhoMed  effective June 30, 1996. The resignation and
severance pay were pursuant to the terms of a consulting  agreement  dated as of
March 7, 1996, between RhoMed and Dr. Rhodes.

EMPLOYMENT AGREEMENTS

       Executive officers of the Company are appointed by the Board of Directors
and serve at the  discretion of the Board of Directors.  Each officer shall hold
his position  until his successor is appointed and qualified.  Mr.  Quilty,  Dr.
Spana and Mr. Putnam each hold their offices pursuant to employment agreements.

         Subsequent  to the Merger,  the Company  adopted,  with  amendments  as
required to reflect the Merger, an employment agreement entered into on November
16, 1995 between RhoMed and Edward J. Quilty.  Pursuant to this  agreement,  Mr.
Quilty is serving as President  and Chief  Executive  Officer of the Company and
RhoMed.  The initial  term of the  employment  agreement  was one year and it is
automatically  renewed for successive  twelve-month  periods unless either party
gives  written  notice to the  contrary,  or unless the  agreement  is otherwise
terminated.  Mr. Quilty's  minimum base salary is $300,000 per year; his current
salary is $321,000 per year.  The Company has agreed to reimburse Mr. Quilty for
premiums and other payments to maintain a $1,000,000 term life insurance  policy
issued in 1992 for the benefit of Mr. Quilty and his  designees.  Mr. Quilty may
also  participate in any benefit plans  available to other senior  executives of
the Company,  and in any directors' and officers'  liability insurance which the
Company maintains.  Pursuant to the employment  agreement,  RhoMed issued to Mr.
Quilty an option to purchase  common stock equal to a 10% fully  diluted  equity
interest in RhoMed as of November  16, 1995,  at a price of $0.01 per share,  to
vest in 36 equal increments monthly during the term of the employment agreement.
By operation of the Merger,  that option became an option for 107,816  shares of
Common Stock at an

                                     Page 41

<PAGE>



exercise price of $0.22 per share  (rounded to the nearest  cent).  To date, Mr.
Quilty  has  exercised  that  option as to 47,918  shares.  The  agreement  also
provides for anti-dilution  protections which,  among other things,  require the
Company to issue additional options with the same exercise price as the original
option, so that Mr. Quilty shall, at all times, have options in the aggregate to
purchase  the  number of shares of Common  Stock  (together  with  Common  Stock
purchased on the exercise of such  options)  equal to not less than 3.75% of the
Company's  outstanding  Common Stock on a fully diluted  basis.  Pursuant to the
anti-dilution  protections,  the  Company  has issued to Mr.  Quilty  additional
anti-dilution  options to  purchase  an  aggregate  of 152,799  shares of Common
Stock,  which  options vest in equal  monthly  increments  so as to become fully
vested 36 months  after the  commencement  of the  employment  agreement.  For a
period of five (5) years after the first  anniversary  of the Company's  initial
post-Merger public offering, Mr. Quilty has piggy-back registration rights as to
all  Common  Stock  which he owns.  If the  Company  terminates  the  employment
agreement for "cause," or if Mr. Quilty  terminates the agreement  without "good
reason," then the  Company's  payment  obligation  is limited to amounts  earned
through the  termination  date, and the option will be  exercisable  only to the
extent  vested.  If Mr.  Quilty  elects to terminate  the  employment  agreement
following a  post-Merger  change in control of the Company,  then the  Company's
payment  obligation is limited to amounts earned through the  termination  date,
but the option  will  immediately  become  exercisable  in full.  If the Company
terminates  the  employment  agreement  without  cause,  or in the  event of Mr.
Quilty's  death  or  disability,  or if Mr.  Quilty  terminates  the  employment
agreement  with good  reason,  then in  addition to amounts  earned  through the
termination  date,  the Company must pay Mr. Quilty one year of his then current
base salary. "Cause," as defined in the employment agreement, consists of fraud,
felony conviction,  refusal to carry out instructions of the Board of Directors,
or governmental  disqualification (all as defined in the employment  agreement).
"Good reason," as defined in the employment agreement, consists of breach by the
Company  of its  obligations  under the  employment  agreement.  The  employment
agreement also includes  non-competition,  confidentiality  and  indemnification
covenants.

         Carl Spana, Ph.D., and Charles Putnam have each entered into employment
agreements with the Company dated September 27, 1996,  pursuant to which each is
serving as an Executive  Vice  President of the Company for a three-year  period
commencing  June 21, 1996.  Effective June 21, 1997, the base salary for each is
$160,500  per year.  Each is  entitled to  participate  in all bonus and benefit
programs  that the  Company  establishes,  to the extent his  position,  tenure,
salary,  age, health and other  qualifications make him eligible to participate.
Each  agreement  allows  either the  Company or the  employee to  terminate  the
agreement  on thirty  (30) days'  notice,  and  contains  other  provisions  for
termination  by the Company for "cause," or by the  employee  for "good  reason"
after a "change in control"  (all as these  terms are defined in the  respective
agreements). Early termination may, in some circumstances, result in accelerated
vesting of stock options  and/or  severance  pay for a nine-month  period at the
rate of base salary,  cash bonus and  benefits  then in effect.  Each  agreement
contains non-competition and confidentiality covenants.



ITEM 11.         SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT.

         Set forth below is  information,  as of September 17, 1997,  concerning
the stock ownership and voting power of all persons (or groups of persons) known
by the Company to be the beneficial  owner of more than five percent (5%) of the
Common  Stock or Series A  Convertible  Preferred  Stock,  each  director of the
Company,  each of the executive  officers  included in the Summary  Compensation
Table and all directors and executive officers of the Company as a group.



                                     Page 42

<PAGE>
<TABLE>
<CAPTION>

                                                                               Amount and Nature                   Percent of
Title of             Name and Address                                            of Beneficial     Percent of        Voting
 Class              of Beneficial Owner                                         Ownership (1)(2)      Class         Power(2)
- --------       -------------------------------                                 -----------------   ----------      ----------
<S>            <C>                                                              <C>                 <C>             <C>

Common         Edward J. Quilty                                                      187,421(3)        5.9%              *
Stock          c/o Palatin Technologies, Inc.
               214 Carnegie Center, Suite 100
               Princeton, NJ 08540

Common         Carl Spana, Ph.D.                                                      85,059(4)        2.7%              *
Stock          c/o Palatin Technologies, Inc.
               214 Carnegie Center, Suite 100
               Princeton, NJ 08540

Common         Charles L. Putnam                                                      48,654(5)        1.6%              *
Stock          c/o Palatin Technologies, Inc.
               214 Carnegie Center, Suite 100
               Princeton, NJ 08540

Common         Michael S. Weiss                                                       26,828(6)           *              *
Stock          c/o Palatin Technologies, Inc.
               214 Carnegie Center, Suite 100
               Princeton, NJ 08540

Common         James T. O'Brien                                                        2,316(7)           *              *
Stock          c/o Palatin Technologies, Inc.
               214 Carnegie Center, Suite 100
               Princeton, NJ 08540

Common         John K.A. Prendergast, Ph.D.                                           12,923(8)           *              *
Stock          c/o Palatin Technologies, Inc.
               214 Carnegie Center, Suite 100
               Princeton, NJ 08540

Common         Lindsay A. Rosenwald, M.D.                                          1,283,056(9)       35.2%             15.2%
Stock          787 Seventh Avenue
               New York, NY 10019

Common         RAQ, LLC                                                              358,245(10)      11.8%              6.2%
Stock          787 Seventh Avenue
               New York, NY 10019

Common         Paramount Capital, Inc.                                               277,782(11)       8.4%              *
Stock          787 Seventh Avenue
               New York, NY 10019

</TABLE>



                                     Page 43

<PAGE>

<TABLE>
<CAPTION>


                                                                               Amount and Nature                   Percent of
Title of             Name and Address                                            of Beneficial     Percent of        Voting
 Class              of Beneficial Owner                                         Ownership (1)(2)      Class         Power(2)
- --------       -------------------------------                                 -----------------   ----------      ----------
<S>            <C>                                                               <C>               <C>                <C> 
Common         Paramount Capital Asset Management, Inc.                              580,535(12)      17.6%              9.1%
Stock          787 Seventh Avenue
               New York, NY 10019

Common         The Aries Trust                                                       397,197(13)      12.4%              6.3%
Stock          c/o MeesPierson (Cayman) Limited
               P.O. Box 2003
               British American Centre, Phase 3
               Dr. Roy's Drive
               George Town, Grand Cayman

Common         Aries Domestic Fund, L.P.                                             183,338(14)       5.9%              2.8%
Stock          787 Seventh Avenue
               New York, NY 10019

Common         Essex Woodlands Health Ventures, L.P.                                 302,419(15)       9.0%              5.2%
Stock            Fund III
               2170 Buckthorne, Suite 170
               The Woodlands, TX  77380

Series A       Lindsay A. Rosenwald, M.D.                                             23,778(16)      15.7%              3.5%
Preferred      787 Seventh Avenue
Stock          New York, NY 10019

Series A       Paramount Capital, Inc.                                                13,778(17)       9.1%              *
Preferred      787 Seventh Avenue
Stock          New York, NY 10019

Series A       Paramount Capital Asset Management, Inc.                               10,000(18)       7.3%              3.5%
Preferred      787 Seventh Avenue
Stock          New York, NY 10019

Series A       Essex Woodlands Health Ventures, L.P.                                  15,000          10.9%              5.2%
Preferred        Fund III
Stock          2170 Buckthorne, Suite 170
               The Woodlands, TX  77380

               All directors and executive officers as a                             370,815(19)      11.1%              1.4%
               group (seven (7) persons)
</TABLE>

- ------------------
*Less than one percent.

(1)      With respect to Common  Stock,  this column  includes  shares of Common
         Stock   issuable  upon  exercise  of  options  or  warrants   currently
         exercisable or exercisable within 60 days following

                                     Page 44

<PAGE>



         September 17, 1997, and shares of Common Stock issuable upon conversion
         of Series A Convertible  Preferred  Stock.  No director or officer owns
         any Series A Convertible Preferred Stock. Beneficial ownership includes
         direct or indirect voting or investment power. All shares listed in the
         table are  beneficially  owned and sole voting and investment  power is
         held by the persons named, except as otherwise noted.

(2)      The  Common  Stock  has one  vote  for  each  share  and the  Series  A
         Convertible  Preferred  Stock has  approximately  80.6  votes for  each
         share,  subject to adjustment  upon the occurrence of certain   events.
         Voting  power is  calculated  on the basis of the  aggregate of  Common
         Stock and  Series A  Convertible  Preferred  Stock  outstanding  as  of
         September 17, 1997. On September 17, 1997, there were 3,041,111  shares
         of Common Stock outstanding and 137,780 shares of Series A  Convertible
         Preferred Stock outstanding,  entitled to a maximum of  2,777,739 votes
         in the aggregate.  In the case of Series A Convertible  Preferred Stock
         voting separately as a class,  voting power is equal to  the percent of
         the class owned.

(3)      Includes (i) 23,959  shares of Common Stock  issuable  upon exercise of
         options  granted  pursuant to RhoMed's  1995 Employee  Incentive  Stock
         Option Plan,  of which  options with respect to 17,969 shares of Common
         Stock are  currently  exercisable  and  options  with  respect to 5,990
         shares of Common Stock will become exercisable within 60 days following
         September 17, 1997;  (ii) 30,000  shares of Common Stock  issuable upon
         exercise of options  granted  pursuant to the 1996 Stock  Option  Plan;
         (iii)  68,699  shares  of  Common  Stock   issuable  upon  exercise  of
         anti-dilution  options  granted by the Company,  of which  options with
         respect to 54,681 shares of Common Stock are currently  exercisable and
         options  with  respect to 14,018  shares of Common  Stock  will  become
         exercisable  within 60 days  following  September  17,  1997;  and (iv)
         16,845  shares of Common  Stock  issuable  upon  exercise  of  non-plan
         options, of which options with respect to 10,107 shares of Common Stock
         are currently  exercisable  and options with respect to 6,738 shares of
         Common Stock will become exercisable within 60 days following September
         17, 1997. Does not include 160,469 shares of Common Stock issuable upon
         exercise of options not exercisable within 60 days following  September
         17, 1997.

(4)      Includes (i) 49,464  shares of Common Stock  issuable  upon exercise of
         currently   exercisable  options  granted  pursuant  to  RhoMed's  1995
         Employee  Incentive and  Non-Qualified  Stock Option Plans; (ii) 15,000
         shares of Common  Stock  issuable  upon  exercise  of  options  granted
         pursuant  to the 1996 Stock  Option  Plan;  and (iii)  8,922  shares of
         Common  Stock  issuable  upon  exercise of non-plan  options.  Does not
         include 42,576 shares of Common Stock issuable upon exercise of options
         not exercisable within 60 days following September 17, 1997.

(5)      Includes (i) 24,732  shares of Common Stock  issuable  upon exercise of
         currently   exercisable  options  granted  pursuant  to  RhoMed's  1995
         Employee  Incentive and  Non-Qualified  Stock Option Plans; (ii) 15,000
         shares of Common  Stock  issuable  upon  exercise  of  options  granted
         pursuant  to the 1996 Stock  Option  Plan;  and (iii)  8,922  shares of
         Common  Stock  issuable  upon  exercise of non-plan  options.  Does not
         include 67,308 shares of Common Stock issuable upon exercise of options
         not exercisable within 60 days following September 17, 1997.

(6)      Includes (i) 11,587  shares of Common Stock  issuable  upon exercise of
         currently exercisable  warrants;  and (ii) 2,316 shares of Common Stock
         issuable  upon  exercise  of  currently   exercisable  options  granted
         pursuant to the 1996 Stock Option Plan.  Does not include  3,750 shares
         of

                                     Page 45

<PAGE>



         Common Stock issuable upon exercise of options granted  pursuant to the
         1996  Stock  Option  Plan  not  exercisable  within  60 days  following
         September 17, 1997.

(7)      Represents  2,316  shares of Common  Stock  issuable  upon  exercise of
         currently exercisable options granted pursuant to the 1996 Stock Option
         Plan.  Does not include  3,750  shares of Common  Stock  issuable  upon
         exercise of options granted pursuant to the Option Plan not exercisable
         within 60 days following September 17, 1997.

(8)      Includes  1,250  shares of  Common  Stock  issuable  upon  exercise  of
         currently exercisable options granted pursuant to the 1996 Stock Option
         Plan.  Does not include  3,750  shares of Common  Stock  issuable  upon
         exercise of options granted pursuant to the Option Plan not exercisable
         within 60 days following September 17, 1997.

(9)      Includes (i) 66,494  shares of Common Stock  issuable upon exercise  of
         currently  exercisable  warrants held by Dr.  Rosenwald;   (ii) 358,245
         shares of Common  Stock owned by RAQ,  LLC, of which Dr.   Rosenwald is
         President;  (iii)  232,734  shares of  Common  Stock   outstanding  and
         131,048  shares of Common  Stock  issuable  upon  conversion  of  6,500
         shares of Series A  Convertible  Preferred  Stock,  owned by The  Aries
         Trust, a Cayman Islands trust ("The Aries Trust");  (iv) 93,189  shares
         of Common Stock outstanding and 70,564 shares of Common Stock  issuable
         upon  conversion  of 3,500  shares of Series A   Convertible  Preferred
         Stock, owned by Aries Domestic Fund, L.P. ("Aries Domestic Fund")   (v)
         19,585  shares of Common  Stock  issuable  upon  exercise of  currently
         exercisable  warrants held by Aries Domestic Fund;  (vi)  33,415 shares
         of Common  Stock  issuable  upon  exercise   of  currently  exercisable
         warrants held by The Aries Trust;  and (vii)  277,782  shares of Common
         Stock   issuable  upon   conversion  of  13,778  shares  of  Series   A
         Convertible Preferred Stock issuable upon exercise of warrants held  by
         Paramount Capital,  exercisable within 60 days following  September 17,
         1997.  Dr.  Rosenwald  shares  voting and  investment  power  as to the
         foregoing shares.  Dr. Rosenwald is the President of Paramount  Capital
         and is the  President,  Chairman of the Board and sole  shareholder  of
         Paramount Capital Asset Management, Inc., which is the general  partner
         of Aries Domestic Fund and the investment  manager of The Aries  Trust.
         Paramount  Capital Asset Management,  Inc. and Dr. Rosenwald   disclaim
         beneficial ownership of the securities held by Aries Domestic Fund  and
         The Aries  Trust,  except to the  extent of their  pecuniary   interest
         therein, if any. Does not include (i) any shares of Common Stock  owned
         by employees of Paramount Capital or Paramount Capital  Investments  of
         which Dr.  Rosenwald  is the Chairman of the Board and   President,  or
         (ii)  warrants  to  purchase  6,250  shares of Common  Stock which  are
         issuable to Paramount Capital or its designees pursuant to a  financial
         advisory services agreement.

(10)     RAQ, LLC shares voting and investment power as to these shares.  All of
         the shares of Common Stock owned by RAQ,  LLC are also  included in the
         beneficial  ownership of Lindsay A.  Rosenwald,  M.D.,  as explained in
         note (9) above.

(11)     Represents  277,782 shares of Common Stock issuable upon  conversion of
         13,778 shares of Series A  Convertible  Preferred  Stock  issuable upon
         exercise  of  placement  agent  warrants  exercisable  within  60  days
         following  September  17,  1997.  All  of  the  shares  purchasable  by
         Paramount  Capital are also  included in the  beneficial  ownership  of
         Lindsay A. Rosenwald, M.D., as explained in note (9) above.

(12)     Includes  (i) 232,734  shares of Common Stock  outstanding  and 131,048
         shares of Common  Stock  issuable  upon  conversion  of 6,500 shares of
         Series A Convertible Preferred Stock, owned by The

                                     Page 46

<PAGE>



         Aries Trust; (ii) 93,189 shares of Common Stock  outstanding and 70,564
         shares of Common Stock  issuable  upon  conversion  of  3,500 shares of
         Series A Convertible  Preferred  Stock,  owned by Aries  Domestic Fund;
         (iii)  19,585  shares  of  Common  Stock  issuable   upon  exercise  of
         currently  exercisable  warrants held by Aries Domestic Fund;  and (iv)
         33,415  shares of Common  Stock  issuable  upon  exercise of  currently
         exercisable  warrants  held by The  Aries  Trust.  Dr.  Rosenwald   and
         Paramount Capital Asset  Management,  Inc. share voting  and investment
         power as to the foregoing shares.  Paramount Capital Asset  Management,
         Inc. and Dr. Rosenwald disclaim beneficial ownership of  the securities
         held by Aries Domestic Fund and The Aries Trust,  except  to the extent
         of their pecuniary  interest therein,  if any. All of the  shares owned
         or purchasable by Paramount  Capital Asset  Management,  Inc.  are also
         included in the beneficial ownership of Lindsay A. Rosenwald, M.D.,  as
         explained in note (9) above.

(13)     Includes (i) 131,048 shares of Common Stock issuable upon conversion of
         6,500 shares of Series A Convertible  Preferred  Stock; and (ii) 33,415
         shares of Common Stock issuable upon exercise of currently  exercisable
         warrants.  The Aries Trust shares voting and investment power as to the
         foregoing  shares.  All of the shares owned or purchasable by The Aries
         Trust are also  included  in the  beneficial  ownership  of  Lindsay A.
         Rosenwald,  M.D. and of Paramount  Capital Asset  Management,  Inc., as
         explained in notes (9) and (12) above.

(14)     Includes (i) 70,564 shares of Common Stock issuable upon  conversion of
         3,500 shares of Series A Convertible  Preferred  Stock; and (ii) 19,585
         shares of Common Stock issuable upon exercise of currently  exercisable
         warrants.  Aries Domestic Fund shares voting and investment power as to
         the foregoing  shares.  All of the shares owned or purchasable by Aries
         Domestic Fund are also included in the beneficial  ownership of Lindsay
         A. Rosenwald, M.D. and of Paramount Capital Asset Management,  Inc., as
         explained in notes (9) and (12) above.

(15)     Represents shares  of  Common Stock  issuable  on  conversion of 15,000
         shares of Series A Convertible Preferred Stock.

(16)     Includes (i) 6,500 shares of Series A Convertible Preferred Stock owned
         by The Aries Trust; (ii) 3,500 shares of Series A Convertible Preferred
         Stock  owned by Aries  Domestic  Fund;  and  13,778  shares of Series A
         Convertible  Preferred  Stock issuable upon exercise of placement agent
         warrants  held  by  Paramount  Capital,   exercisable  within  60  days
         following   September  17,  1997.  Dr.   Rosenwald  shares  voting  and
         investment power as to the foregoing shares. See note (9) above.

(17)     Represents shares of Series A Convertible Preferred Stock issuable upon
         exercise  of  placement  agent  warrants  exercisable  within  60  days
         following  September  17,  1997.  All  of  the  shares  purchasable  by
         Paramount  Capital are also  included in the  beneficial  ownership  of
         Lindsay A. Rosenwald, M.D., as explained in note (9) above.

(18)     Includes (i) 6,500 shares of Series A Convertible Preferred Stock owned
         by The Aries  Trust;  and (ii)  3,500  shares  of Series A  Convertible
         Preferred Stock owned by Aries Domestic Fund.  Paramount  Capital Asset
         Management, Inc. shares voting and investment power as to the foregoing
         shares. See note (12) above.

(19)     Includes 286,626 shares of Common Stock issuable on exercise of options
         and warrants,  of which 259,880 are  currently  exercisable  and 26,746
         will become  exercisable  within 60 days following  September 17, 1997.
         Does not include  304,446 shares of Common Stock issuable upon exercise
         of options not exercisable within 60 days following September 17, 1997.

                                     Page 47

<PAGE>



ITEM 12.          CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS.

         In  December  1996 the  Company  engaged  Paramount  Capital  to act as
exclusive  placement  agent  for  the  Series  A  Offering.  Mr.  Weiss  and Dr.
Prendergast,  directors of the Company,  recused  themselves  from voting on the
matter,  and the Series A Offering was  approved by a vote of the  disinterested
directors.  Mr.  Weiss is Senior  Managing  Director  of  Paramount  Capital and
Paramount  Capital  Investments,  an  affiliate of  Paramount  Capital,  and Dr.
Prendergast is Managing Director of Paramount Capital Investments.  As placement
agent, Paramount Capital received a 9% commission,  amounting to $1,240,020, and
a 4%  non-accountable  expense  allowance,  amounting to $551,120,  on the gross
proceeds of the Series A Offering,  for an aggregate  total of  $1,791,140,  and
Preferred  Stock  Placement  Warrants  to  purchase  13,778  shares  of Series A
Convertible Preferred Stock, at an exercise price of $110 per share. The Company
also  agreed  to  indemnify  Paramount  Capital  against  certain   liabilities,
including  liabilities  arising under the Securities Act, in connection with the
Series A Offering.

         Pursuant to the placement  agency  agreement for the Series A Offering,
the Company entered into an introduction  agreement with Paramount  Capital (the
"Introduction  Agreement"),  under which Paramount Capital acts as the Company's
non-exclusive  financial  advisor for a minimum  period of eighteen  (18) months
commencing January 1, 1997, and will receive (i) out-of-pocket expenses incurred
in connection with services performed under the Introduction  Agreement,  (ii) a
retainer of $72,000 and (iii)  percentage  or lump sum success fees in the event
that Paramount  Capital assists the Company in connection with certain financing
and  strategic  transactions.  The  Introduction  Agreement  replaced  a similar
agreement in effect from September 1, 1996 through  December 31, 1996,  pursuant
to which Paramount Capital received a retainer of $5,000 per month and a warrant
to purchase 6,250 shares of Common Stock at $9.00 per share.

         Prior to the Merger, Paramount Capital served as placement agent for an
offering of shares of RhoMed common stock (the "RhoMed  Common Stock  Offering")
authorized by RhoMed's  board of directors on March 4, 1996;  the RhoMed Class B
Offering authorized by RhoMed's board of directors on November 27, 1995; and the
RhoMed Class A Offering  authorized  by RhoMed's  board of directors on July 28,
1995. In the RhoMed Class A Offering, the RhoMed Class B Offering and the RhoMed
Common Stock  Offering,  RhoMed paid Paramount  Capital  commissions and fees of
$90,000, $110,500 and $1,254,000, respectively, and issued warrants to designees
of Paramount  Capital to purchase RhoMed common stock,  which as a result of the
Merger were converted into warrants to purchase 20,737 shares of Common Stock at
$0.22 per share;  1,958 shares of Common  Stock at $6.51 per share;  and 177,796
shares of Common Stock at $6.51 per share, respectively.

         Effective  April  1995,  RhoMed  entered  into a letter of intent  with
Castle Group under which (i) Castle Group agreed to arrange for a line of credit
of up to $300,000 to finance  ongoing  operations  of RhoMed;  (ii) Castle Group
agreed to arrange for future  financings for RhoMed;  and (iii) RhoMed agreed to
sell to Castle  Group or its  designees,  for nominal  consideration,  4,000,000
shares of RhoMed Series A Preferred  Stock.  This  resulted,  at the time of the
investment,  in Castle Group and affiliates of Castle Group  obtaining  majority
ownership and control of RhoMed.  Castle Group is owned by Lindsay A. Rosenwald,
M.D., and is under common control with Paramount Capital. Pursuant to the letter
of intent,  RhoMed borrowed the maximum amount,  and paid off the line of credit
in full in September 1995. The average  interest rate for the line of credit was
10.90% and the total interest paid was $8,005.

         On  July 24, 1995,  Michael  S.  Weiss  and  Carl  Spana,  Ph.D.,  were
appointed to the board of directors of RhoMed.   Dr.  Spana  was  an employee of
Castle Group at the time of his appointment to RhoMed's board

                                     Page 48

<PAGE>



of  directors.  The  RhoMed  Class A  Offering  was  ratified  by  disinterested
stockholders  of RhoMed on August  15,  1995;  the RhoMed  Class B Offering  was
approved by disinterested directors with Mr. Weiss and Dr. Spana abstaining; and
the  placement  agent for the RhoMed  Common  Stock  Offering was selected by an
offering  committee of RhoMed's board of directors,  consisting of disinterested
directors.

         As a result of the RhoMed offerings described above, Dr. Rosenwald, Mr.
Weiss, and Dr. Spana received equity  securities of the Company in the following
amounts:  Dr.  Rosenwald  received  warrants to purchase 15,079 shares of Common
Stock at $0.22 per share and warrants to purchase  51,416 shares of Common Stock
at $6.51 per share; RAQ, LLC, a company  controlled by Dr.  Rosenwald,  received
414,267  shares of Common  Stock;  Mr. Weiss  received  12,925  shares of Common
Stock,  warrants to purchase 1,464 shares of Common Stock at $0.22 per share and
warrants to purchase  10,123 shares of Common Stock at $6.51 per share;  and Dr.
Spana received 11,673 shares of Common Stock.

         Dr.  Rosenwald  is the  President,  Chairman  of the  Board   and  sole
stockholder of Paramount Capital Asset Management,  Inc., the general partner of
Aries Domestic Fund and  investment  manager of The Aries Trust  (together,  the
"Aries  Entities").  The Aries Entities  taken together  purchased the following
equity  securities:  10,000  shares of  Series A  Convertible  Preferred  Stock,
convertible into 201,612 shares of Common Stock, 322,673 shares of Common Stock,
warrants  to  purchase  4,608  shares of Common  Stock at $2.71 per  share,  and
warrants to purchase 13,824 shares of Common Stock at $.22 per share.  Following
the RhoMed  Class A,  Class B and  Common  Stock  Offerings,  Paramount  Capital
assigned to the Aries Entities those portions of Paramount  Capital's  placement
agent warrants attributable to the investments of the Aries Entities, consisting
of  warrants  to  purchase  2,073  shares of Common  Stock at $.22 per share and
32,497 shares of Common Stock at $6.51 per share.

         Mr. Quilty,  Dr. Spana, Mr. Putnam and Non-Employee Directors have been
granted options to purchase Common Stock.  See  Items 10 and 11.

         Buck A. Rhodes,  Ph.D.  was a director of RhoMed from  inception  until
June 30, 1996, was President of RhoMed from  inception  until March 7, 1996, and
was a director of the Company from June 25, 1996 through June 30, 1996.  Under a
consulting  agreement  dated March 7, 1996  between Dr.  Rhodes and RhoMed,  Dr.
Rhodes was paid $51,023 in accrued salary and $36,000 as severance  compensation
for resigning from the board of RhoMed,  and is being paid $6,833 per month from
April 1996 through March 1998 for consulting services.



ITEM 13.          EXHIBITS AND REPORTS ON FORM 8-K.

(a)      EXHIBITS

         The following  exhibits are filed with this Report,  or incorporated by
reference as noted:

2.1        Agreement  and Plan of  Reorganization  dated as of April 12, 1996 by
           and between Interfilm,  Inc., Interfilm  Acquisition Corp. and RhoMed
           Incorporated. (a)

2.2        Waiver and  Consent  dated as of June 24,  1996,  between  Interfilm,
           Inc., Interfilm Acquisition Corp. and RhoMed Incorporated. (b)

3.1        Restated  Certificate of Incorporation of the Company,  as filed with
           the Delaware Secretary of State on November 3, 1993. (c)

                                     Page 49

<PAGE>



3.2        Amendment  to  the  Restated  Certificate  of  Incorporation  of  the
           Company,  as filed with the  Delaware  Secretary of State on July 19,
           1996. (d)

3.3        Bylaws of the Company. (e)

3.4        Amended Certificate of Designation of Series A Convertible  Preferred
           Stock of the Company, filed on June 24, 1996. (f)

3.5        Amended Certificate of Designation of Series B Preferred Stock of the
           Company, filed on June 24, 1996. (g)

3.6        Certificate of Designation of Series A Convertible Preferred Stock of
           the Company, filed on February 21, 1997. (e)

3.7        Amendment  to  the  Restated  Certificate  of  Incorporation  of  the
           Company, filed on September 5, 1997.**

4.1        Specimen Certificate for Common Stock. (h)

4.2        Patent  Assignment and License  Agreement  dated as of July 15, 1993,
           between RhoMed  Incorporated and Aberlyn Capital  Management  Limited
           Partnership. (b)

4.3        Master  Lease  Agreement  dated  November 16,  1994,  between  RhoMed
           Incorporated and Aberlyn Capital Management Limited Partnership. (b)

4.4        Letter Agreement, dated as of April 28, 1995, between Aberlyn Capital
           Management Limited Partnership and RhoMed Incorporated. (b)

4.5        Stock Purchase and Modification Agreement, dated as of June 24, 1996,
           between  Aberlyn  Capital  Management  Limited  Partnership,  Aberlyn
           Holding Company, Inc. and RhoMed Incorporated. (b)

4.6        Specimen Certificate for Series A Convertible Preferred Stock. (e)

10.01      Lease  between  Charles C. and Ellen C.  France  Revocable  Trust and
           RhoMed Incorporated dated December 18, 1992. (b)

10.02      Amendment,  dated  November 1, 1993, to Lease between  Charles C. and
           Ellen C. France Revocable Trust and RhoMed Incorporated. (b)

10.03      Second Amendment, dated July 5, 1996, to Lease between Charles C. and
           Ellen C. France Revocable Trust and RhoMed Incorporated. (b)

10.04      RhoMed Incorporated 1995 Employee Incentive Stock Option Plan. (b)*

10.05      RhoMed Incorporated 1995 Nonqualified Stock Option Plan. (b)*

10.06      1996 Stock Option Plan of the Company. (e)*

10.07      Employment  Agreement  dated as of November 16, 1995,  between RhoMed
           Incorporated and Edward J. Quilty. (b)*

10.08      Employment  Agreement dated as of September 27, 1996, between Palatin
           Technologies, Inc. and Carl Spana. (b)*

                                     Page 50

<PAGE>



10.09      Employment  Agreement dated as of September 27, 1996, between Palatin
           Technologies, Inc. and Charles Putnam. (b)*

10.10      Class C Warrant for the  Purchase of shares of Common Stock issued to
           William I. Franzblau June 24, 1996. (b)

10.11      License   Agreement  between  Rougier  Bio-Tech  Limited  and  RhoMed
           Incorporated dated May 1, 1992. (b)

10.12      License   Agreement   between  Sterling   Winthrop  Inc.  and  RhoMed
           Incorporated dated November 2, 1992. (b)

10.13      Assignment and Assumption  dated January 21, 1994,  between  Sterling
           Winthrop, Inc. and Burroughs Wellcome Co. (b)

10.14      Option Agreement between RhoMed Incorporated and The Wistar Institute
           of Anatomy and Biology dated August 22, 1996. (b)

10.15      Consulting  Agreement  dated  as of  March 7,  1995,  between  RhoMed
           Incorporated and Buck A. Rhodes. (b)

10.16      Form of Class A Warrant. (b)

10.17      Form of Placement Agent Warrant for the Class A Offering. (b)

10.18      Form of Unit Purchase  Agreement for the Class A Offering,  including
           registration  rights  referred  to in the Form of Class A Warrant and
           Form of Placement Agent Warrant for the Class A Offering. (b)

10.19      Form of Class B Warrant. (b)

10.20      Form of Placement Agent Warrant for the Class B Offering. (b)

10.21      Form of Unit Purchase  Agreement for the Class B Offering,  including
           registration  rights  referred  to in the Form of Class B Warrant and
           Form of Placement Agent Warrant for the Class B Offering. (b)

10.22      Form of Placement Agent Warrant for the RhoMed Common Stock Offering.
           (b)

10.23      Form of Common Stock  Purchase  Agreement for the RhoMed Common Stock
           Offering,  including  registration  rights referred to in the Form of
           Placement Agent Warrant for the RhoMed Common Stock Offering. (b)

10.24      Lease  between  Adelante   Development   Center,   Inc.  and  Palatin
           Technologies, Inc. dated October 10, 1996. (f)

10.25      License  Option  Agreement  dated as of December  18,  1996,  between
           Palatin Technologies, Inc. and Nihon Medi-Physics Co. Ltd. (j)

10.26      Lease between Carnegie 214 Associates Limited Partnership and Palatin
           Technologies, Inc. dated May 6, 1997.**

10.27      Lease  between  WHC-Six Real Estate,  L.P. and Palatin  Technologies,
           Inc. dated March 13, 1997.**

                                     Page 51

<PAGE>



10.28      Amendment  to  Employment  Agreement  dated as of November  16, 1995,
           between RhoMed Incorporated and Edward J. Quilty.* **

16.1       Letter dated July 19, 1996 from Deloitte & Touche LLP. (k)

21.1       Current list of subsidiaries of the Company. (b)

27         Financial Data Schedule.**

99.1       Certificate of Limited  Partnership  of "The  Interfilm  Stockholders
           Limited  Partnership," as filed with the Delaware  Secretary of State
           on June 17, 1996. (b)

99.2       Agreement  of  Limited  Partnership  of  The  Interfilm  Stockholders
           Limited Partnership, dated June 11, 1996. (b)

99.3       The Interfilm Stockholders Trust, established by Interfilm,  Inc. and
           Interfilm Technologies, Inc. on June 11, 1996. (b)

99.4       General Bill of Sale,  Assignment and Assumption  Agreement among, on
           the one hand, Interfilm, Inc. and Interfilm Technologies, Inc. and on
           the other hand, The Interfilm Stockholders Limited Partnership, dated
           June 25, 1996. (b)

                                NOTES TO EXHIBITS

                 *     A   management   contract   or   compensatory   plan   or
                       arrangement.

                 **    Filed as an exhibit to this Report.

                 (a)   Incorporated by reference to Exhibit 2.1 of the Company's
                       Form 8-K dated June 25, 1996,  filed with the  Commission
                       on July 10, 1996.

                 (b)   Incorporated  by  reference  and  previously  filed as an
                       exhibit to the  Company's  Form 10-KSB  Annual Report for
                       the period ended June 30, 1996, filed with the Commission
                       on September 27, 1996.

                 (c)   Incorporated by reference to Exhibit 3.1 of the Company's
                       Form 8-K dated July 19, 1996,  filed with the  Commission
                       on August 9, 1996.

                 (d)   Incorporated by reference to Exhibit 3.2 of the Company's
                       Form 8-K dated July 19, 1996,  filed with the  Commission
                       on August 9, 1996.

                 (e)   Incorporated  by  reference  and  previously  filed as an
                       exhibit to the Company's  Form 10-QSB/A  Amendment  No. 2
                       for the  quarter  ended  March 31,  1997,  filed with the
                       Commission on July 17, 1997.

                 (f)   Incorporated by reference to Exhibit 3.3 of the Company's
                       Form 8-K dated July 19, 1996,  filed with the  Commission
                       on August 9, 1996.

                 (g)   Incorporated by reference to Exhibit 3.4 of the Company's
                       Form 8-K dated July 19, 1996,  filed with the  Commission
                       on August 9, 1996.

                 (h)   Incorporated by Reference to Exhibit 4.1 of the Company's
                       Form 8-K dated July 19, 1996,  filed with the  Commission
                       on August 9, 1996.

                                     Page 52

<PAGE>



                 (i)   Incorporated   by  reference  to  Exhibit  10.24  of  the
                       Company's Form 10-QSB for the quarter ended September 30,
                       1996, filed with the Commission on November 13, 1996.

                 (j)   Incorporated   by  reference  to  Exhibit  10.25  of  the
                       Company's  Form 10-QSB/A  Amendment No. 2 for the quarter
                       ended  December 31, 1996,  filed with the  Commission  on
                       September 12, 1997.

                 (k)   Incorporated   by   reference  to  Exhibit  16.1  of  the
                       Company's Form 8-K/A dated June 25, 1996,  filed with the
                       Commission on July 23, 1996.

b)    REPORTS ON FORM 8-K

      One  report  on  Form 8-K was  filed  by  the  Company  during  the  three
months ended June 30, 1997. The report was filed on April 18, 1997,  with a date
of  April  8,  1997,  and  reported  on Item 5,  Other  Events,  relating  to an
announcement of an interim closing on the Company's Series A Offering.

                                     Page 53

<PAGE>



                                   SIGNATURES

         In  accordance  with  Section  13 or 15(d)  of the  Exchange  Act,  the
registrant  caused  this  Report to be signed on its behalf by the  undersigned,
thereunto duly authorized.

                                        PALATIN TECHNOLOGIES, INC.



Date: September 26, 1997                By:  /s/ Edward J. Quilty
                                           --------------------------
                                           Edward J. Quilty
                                           Chairman of the Board, President and 
                                           Chief Executive Officer

         In accordance  with the Exchange Act, this report has been signed below
by the following  persons on behalf of the  registrant and in the capacities and
on the dates indicated.

      Signature                   Titles                              Date
      ---------                   ------                              ----  

/s/ Edward J. Quilty        Chairman of the Board,            September 26, 1997
- --------------------------  President and Chief 
                            Executive Officer
                            (principal executive officer)


/s/ Carl Spana              Executive Vice President          September 26, 1997
- --------------------------  and Director  
Carl Spana


/s/ John J. McDonough       Vice President and Chief          September 26, 1997
- -------------------------   Financial Officer 
John J. McDonough           (principal financial and 
                            accounting officer)

/s/ Michael S. Weiss        Director                          September 26, 1997
- -------------------------   
Michael S. Weiss


/s/ James T. O'Brien        Director                          September 26, 1997
- -------------------------
James T. O'Brien


/s/ John K.A. Prendergast   Director                          September 26, 1997
- -------------------------
John K.A. Prendergast

                                     Page 54

<PAGE>



                                TABLE OF CONTENTS
                              FINANCIAL STATEMENTS


The  following  financial  statements  of the  Company are filed as part of this
Report:


Report of Independent Public Accountants, Arthur Andersen LLP................F-1

Consolidated Balance Sheets..................................................F-2

Consolidated Statements of Operations........................................F-3

Consolidated Statements of Stockholders' Equity (Deficit)....................F-4

Consolidated Statements of Cash Flows........................................F-6

Notes to Consolidated Financial Statements...................................F-8


                                     Page 55

<PAGE>





                    Report of Independent Public Accountants
                    ----------------------------------------



To the Stockholders and Board of Directors of
  Palatin Technologies, Inc.:

We  have  audited  the  accompanying  consolidated  balance  sheets  of  Palatin
Technologies,  Inc.  (a  Delaware  corporation  in the  development  stage)  and
subsidiaries  as of  June  30,  1997  and  1996,  and the  related  consolidated
statements of operations,  stockholders' equity (deficit) and cash flows for the
year ended June 30, 1997,  the ten months  ended June 30,  1996,  the year ended
August 31, 1995 and the period from  inception  (January  28,  1986) to June 30,
1997.  These  financial  statements  are  the  responsibility  of the  Company's
management.  Our  responsibility  is to express  an  opinion on these  financial
statements based on our audits.

We  conducted  our  audits  in  accordance  with  generally   accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement.  An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements.  An audit also includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements  referred to above present fairly, in
all material respects, the financial position of Palatin Technologies,  Inc. and
subsidiaries  as of June 30, 1997 and 1996, and the results of their  operations
and their cash flows for each of the periods indicated above, in conformity with
generally accepted accounting principles.


                                              ARTHUR ANDERSEN LLP

Philadelphia, PA
  August 20, 1997


                                       F-1

<PAGE>

                           PALATIN TECHNOLOGIES, INC.
                        (A Development Stage Enterprise)
                           Consolidated Balance Sheets

<TABLE>
<CAPTION>


                                                                                                    JUNE 30, 1997   JUNE 30, 1996
                                                                                                     ------------    ------------
<S>                                                                                                  <C>            <C>  
ASSETS
Current assets:
  Cash and cash equivalents, including restricted cash of $201,211
     at June 30, 1997 ............................................................................   $ 12,806,717    $  6,791,300
  Accounts receivable ............................................................................         84,562           4,574
  Prepaid expenses and other .....................................................................        174,996          66,430
                                                                                                     ------------    -------------
      Total current assets .......................................................................     13,066,275       6,862,304

Property and equipment, net ......................................................................        922,096          96,354
Intangibles, net of accumulated amortization of $103,743 and
  $91,336, respectively ..........................................................................         74,494          82,547
                                                                                                     ------------    -------------
                                                                                                     $ 14,062,865    $  7,041,205
                                                                                                     ============    =============

LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
  Accounts payable ...............................................................................   $    316,273    $    214,424
  Accrued expenses ...............................................................................      1,472,905         769,260
  Current portion of long-term financing .........................................................        869,549         311,695
  Notes payable ..................................................................................         80,000               -
  Senior bridge notes, including note to related party of $110,000
    as of June 30, 1996 ..........................................................................              -       1,100,000
                                                                                                     -------------   -------------
      Total current liabilities ..................................................................      2,738,727       2,395,379

Notes payable ....................................................................................              -          80,000
Deferred license revenue .........................................................................        550,000               -
Long-term financing ..............................................................................        939,590       1,727,619
                                                                                                     -------------   -------------
                                                                                                        4,228,317       4,202,998
                                                                                                     -------------   -------------

Commitments and contingencies (Note 9)

Stockholders' equity:
  Preferred stock, $.01 par value, 10,000,000 and 2,000,000 shares
    authorized and 137,780 and no shares issued as of
    June 30, 1997 and 1996, respectively .........................................................          1,378               -
  Common stock, $.01 par value, 75,000,000 and 25,000,000 shares
    authorized and 3,020,373 and 2,884,694 shares issued as of
    June 30, 1997 and 1996, respectively .........................................................         30,204          28,847
  Additional paid-in capital .....................................................................     23,740,864      10,890,935
  Warrants .......................................................................................        573,537               -
  Common stock earned but not issued .............................................................              -          53,030
  Treasury stock, no and 308 shares at cost, respectively ........................................              -          (1,667)
  Deferred compensation ..........................................................................     (1,078,333)              -
  Deficit accumulated during development stage ...................................................    (13,433,102)     (8,132,938)
                                                                                                     -------------   -------------
                                                                                                        9,834,548       2,838,207
                                                                                                     -------------   -------------

                                                                                                     $ 14,062,865    $  7,041,205
                                                                                                     =============   =============

</TABLE>



The accompanying notes to consolidated financial statements are an integral part
of these statements.


                                      F-2


<PAGE>


                           PALATIN TECHNOLOGIES, INC.
                        (A Development Stage Enterprise)
                      Consolidated Statements of Operations



<TABLE>
<CAPTION>
                                                                     Inception
                                                                 (January 28, 1986)       Year        Ten Months           Year
                                                                      through            Ended           Ended            Ended
                                                                   June 30, 1997     June 30, 1997   June 30, 1996   August 31, 1995
                                                                 -----------------   -------------   -------------   ---------------
<S>                                                                   <C>              <C>            <C>             <C>  
REVENUES:
     Grants and contracts .....................................       $  3,210,685     $   350,173    $          -    $          -
     License fees and royalties ...............................            684,296         350,000               -          64,296
     Product ..................................................            318,917          22,184          24,457          33,606
                                                                      -------------    ------------   -------------   -------------

          Total revenues ......................................          4,213,898         722,357          24,457          97,902
                                                                      -------------    ------------   -------------   -------------
OPERATING EXPENSES:
     Research and development .................................          7,806,391       3,409,983         869,896         619,354
     General and administrative ...............................          7,552,844       2,533,883       1,366,343         776,291
     Restructuring charge .....................................            284,000               -         284,000               -
     Net intangibles write down ...............................            259,334               -         259,334               -
                                                                      -------------    ------------   -------------   -------------
          Total operating expenses ............................         15,902,569       5,943,866       2,779,573       1,395,645
                                                                      -------------    ------------   -------------   -------------

OTHER INCOME (EXPENSES):
     Interest income ..........................................            367,389         296,009          10,515           2,744
     Interest expense .........................................         (1,417,850)       (374,664)       (459,308)       (343,865)
     Placement agent commissions and
          fees on debt offering ...............................           (168,970)              -        (168,970)              -
     Merger costs .............................................           (525,000)              -        (525,000)              -
                                                                      -------------    ------------   -------------   -------------

          Total other (expenses) ..............................         (1,744,431)        (78,655)     (1,142,763)       (341,121)
                                                                      -------------    ------------   -------------   -------------
NET LOSS ......................................................        (13,433,102)     (5,300,164)     (3,897,879)     (1,638,864)

PREFERRED STOCK DIVIDEND ......................................         (2,888,935)     (2,888,935)              -               -
                                                                      -------------    ------------   -------------   ------------- 

NET LOSS ATTRIBUTABLE TO
     COMMON STOCKHOLDERS ......................................       $(16,322,037)    $(8,189,099)   $ (3,897,879)   $ (1,638,864)
                                                                      =============    ============   =============   =============

Weighted average number of common
     shares outstanding .......................................            559,609       2,924,073         585,356         309,548
                                                                      =============   =============   =============   =============

Net loss per common share .....................................       $     (29.17)   $      (2.80)   $      (6.66)   $      (5.29)
                                                                      =============   =============   =============   =============
</TABLE>





The accompanying notes to consolidated financial statements are an integral part
of these statements.


                                      F-3
<PAGE>


                           PALATIN TECHNOLOGIES, INC.
                        (A Development Stage Enterprise)
            Consolidated Statements of Stockholders' Equity (Deficit)



<TABLE>
<CAPTION>

                                                                              Preferred Stock
                                                                ------------------------------------------------------------
                                                                   Shares        Amount         Subscriptions     Receivable
                                                                -----------    ------------    ----------------  ------------
<S>                                                            <C>             <C>             <C>               <C> 
Balance at inception ........................................            -     $         -     $             -   $ -
   Preferred stock subscriptions ............................        4,000          (4,000)
   Issuance of shares from inception ........................            -               -                   -            -
   Net loss from inception ..................................            -               -                   -            -
                                                                -----------    ------------    ----------------  ------------
Balance, August 31, 1995 ....................................            -               -               4,000       (4,000)
   Preferred stock subscriptions ............................            -               -              (4,000)       4,000
   Issuance of preferred shares .............................    4,000,000           4,000                   -            -
   Issuance of common shares on
      $10,395,400 private placement .........................            -               -                   -            -
   Shares earned but not issued .............................            -               -                   -            -
   Issuance of common shares ................................            -               -                   -            -
   Net loss .................................................            -               -                   -            -
                                                                -----------    ------------    ----------------  -----------

Balance, June 25, 1996 ......................................    4,000,000           4,000                   -            -
  Conversion to Palatin Technologies, Inc. ..................   (4,000,000)         (4,000)                  -            -
                                                                -----------    ------------    ----------------  -----------
Adjusted balance, June 25, 1996 .............................            -               -                   -            -
  Shares outstanding of Palatin
    Technologies, Inc. ......................................            -               -                   -            -
  Issuance of common shares .................................            -               -                   -            -
  Purchase of treasury stock ................................            -               -                   -            -
                                                                -----------    ------------    ----------------  -----------

Balance, June 30, 1996 ......................................            -               -                   -            -
   Issuance of preferred shares, net of expenses ............      137,780           1,378                   -            -
   Shares earned but not issued .............................            -               -                   -            -
   Issuance of common shares ................................            -               -                   -            -
   Retirement of treasury stock .............................            -               -                   -            -
   Issuance of stock options below fair
     market value ...........................................            -               -                   -            -
   Amortization of deferred compensation ....................            -               -                   -            -
   Net loss .................................................            -               -                   -            -
                                                                 ----------    ------------    ----------------  -----------
 
Balance, June 30, 1997 ......................................      137,780     $     1,378     $             -   $        -
                                                                ===========    ============    ================  ===========
</TABLE>



The accompanying notes to consolidated financial statements are an integral part
of these statements.

                                      F-4

<PAGE>


                           PALATIN TECHNOLOGIES, INC.
                        (A Development Stage Enterprise)
            Consolidated Statements of Stockholders' Equity (Deficit)

                                  - Continued -

<TABLE>
<CAPTION>
                                                                          Common Stock
                                            -------------------------------------------------------------------
                                                                                                      Paid-in
                                                                           Additional   Earned but  Capital from
                                               Shares         Amount   Paid-in Capital  not Issued    Warrants
                                            ------------  -------------  -------------  ----------  ------------
<S>                                         <C>           <C>           <C>             <C>         <C>
Balance at inception .....................            -   $          -   $          -   $       -   $       -
   Preferred stock subscriptions .........            -              -              -           -           -
   Issuance of shares from inception .....    6,922,069      1,177,786              -     110,833     100,000
   Net loss from inception ...............            -              -              -           -           -
                                             -----------  -------------  -------------  ----------  ----------
Balance, August 31, 1995 .................    6,922,069      1,177,786              -     110,833     100,000
   Preferred stock subscriptions .........            -              -              -           -           -
   Issuance of preferred shares ..........            -              -              -           -           -
   Issuance of common shares on
      $10,395,400 private placement ......   41,581,600      9,139,303              -           -           -
   Shares earned but not issued ..........            -              -              -     266,743           -
   Issuance of common shares .............    1,054,548        458,977              -    (324,546)   (100,000)
   Net loss ..............................            -              -              -           -           -
                                             -----------  -------------  -------------  ----------  ----------

Balance, June 25, 1996 ...................   49,558,217     10,776,066              -      53,030           -
  Conversion to Palatin Technologies, Inc.  (46,807,465)   (10,748,558)    10,752,558           -           -
                                             -----------  -------------  -------------  ----------  ----------
Adjusted balance, June 25, 1996 ..........    2,750,752         27,508     10,752,558      53,030           -
  Shares outstanding of Palatin
    Technologies, Inc. ...................      108,188          1,082         (1,082)          -           -
  Issuance of common shares ..............       25,754            257        139,459           -           -
  Purchase of treasury stock .............            -              -              -           -           -
                                             -----------  -------------  -------------  ----------  ----------

Balance, June 30, 1996 ...................    2,884,694         28,847     10,890,935      53,030           -
   Issuance of preferred shares, net
     of expenses .........................            -              -     11,062,116           -     573,537
   Shares earned but not issued ..........            -              -              -     250,141           -
   Issuance of common shares .............      135,987          1,360        316,761    (303,171)          -
   Retirement of treasury stock ..........         (308)            (3)        (1,664)          -           -
   Issuance of stock options below fair
     market value ........................            -              -      1,472,716           -           -
   Amortization of deferred compensation .            -              -              -           -           -
   Net loss ..............................            -              -              -           -           -
                                             -----------  -------------  -------------  ----------  ----------
Balance, June 30, 1997 ...................    3,020,373   $     30,204   $ 23,740,864   $       -   $ 573,537
                                             ===========  =============  =============  ==========  ==========



</TABLE>


    
The accompanying notes to consolidated financial statements are an integral part
of these statements.

                                      F-5

<PAGE>

                           PALATIN TECHNOLOGIES, INC.
                        (A Development Stage Enterprise)
            Consolidated Statements of Stockholders' Equity (Deficit)
                                  - Continued -


<TABLE>
<CAPTION>
                                                                            Deficit
                                                                          Accumulated
                                                           Unamortized      During
                                               Treasury     Deferred     Development
                                                Stock     Compensation       Stage          Total
                                           ----------- ---------------  -------------   ------------ 
<S>                                         <C>         <C>            <C>              <C> 
Balance at inception .....................  $       -   $         -    $          -     $          -
   Preferred stock subscriptions .........          -             -               -                -
   Issuance of shares from inception .....          -             -               -        1,388,619
   Net loss from inception ...............          -             -      (4,235,059)      (4,235,059)
                                            ----------  ------------   -------------    -------------
Balance, August 31, 1995 .................          -             -      (4,235,059)      (2,846,440)
   Preferred stock subscriptions .........          -             -               -                -
   Issuance of preferred shares ..........          -             -               -            4,000
   Issuance of common shares on  
      $10,395,400 private placement ......          -             -               -        9,139,303
   Shares earned but not issued ..........          -             -               -          266,743
   Issuance of common shares .............          -             -               -           34,431
   Net loss ..............................          -             -      (3,897,879)      (3,897,879)
                                            ----------  ------------   -------------    -------------

Balance, June 25, 1996 ...................          -             -      (8,132,938)       2,700,158
  Conversion to Palatin Technologies, Inc.          -             -               -                -
                                            ----------  ------------   -------------    -------------
Adjusted balance, June 25, 1996 ..........          -             -      (8,132,938)       2,700,158
  Shares outstanding of Palatin
    Technologies, Inc. ...................          -             -               -                -
  Issuance of common shares ..............          -             -               -          139,716
  Purchase of treasury stock .............     (1,667)            -               -           (1,667)
                                            ----------  ------------   -------------    -------------

Balance, June 30, 1996 ...................     (1,667)            -      (8,132,938)       2,838,207
   Issuance of preferred shares, net  
     of expenses .........................          -             -               -       11,637,031
   Shares earned but not issued ..........          -             -               -          250,141
   Issuance of common shares .............          -             -               -           14,950
   Retirement of treasury stock ..........      1,667             -               -                -
   Issuance of stock options below fair
     market value ........................          -    (1,472,716)              -                -
   Amortization of deferred compensation .          -       394,383               -          394,383
   Net loss ..............................          -             -      (5,300,164)      (5,300,164)
                                            ----------  ------------   -------------    -------------
Balance, June 30, 1997 ...................  $       -   $(1,078,333)    $(13,433,102)   $  9,834,548
                                            ==========  ============   ==============   =============

</TABLE>



<PAGE>

                           PALATIN TECHNOLOGIES, INC.
                        (A Development Stage Enterprise)
                      Consolidated Statements of Cash Flows

<TABLE>
<CAPTION>

                                                            Inception
                                                        (January 28, 1986)        Year           Ten Months           Year
                                                             through             Ended             Ended             Ended
                                                          June 30, 1997      June 30, 1997     June 30, 1996    August 31, 1995
                                                         ----------------  ----------------  ----------------  ----------------
<S>                                                         <C>              <C>              <C>               <C>    

CASH FLOWS FROM OPERATING ACTIVITIES:
  Net loss ...............................................  $(13,433,102)    $ (5,300,164)    $ (3,897,879)     $ (1,638,864)
  Adjustments to reconcile net loss to net cash
    used for operating activities:
      Depreciation and amortization ......................       374,494           65,920           68,005            85,947
      Interest expense on note payable ...................        72,691           19,304            6,667             8,000
      Accrued interest on long-term financing ............       796,038                -          293,380           320,709
      Accrued interest on short-term financing ...........         7,936         (100,000)         100,000             7,936
      Intangibles and equipment write down ...............       278,318                -          278,318                 -
      Equity and notes payable issued for expenses .......       546,188          250,141          174,147            10,350
      Settlement with consultant .........................       (28,731)               -                -                 -
      Deferred revenue ...................................       550,000          550,000                -                 -
      Amortization of deferred compensation ..............       394,383          394,383                -                 -
      Changes in certain operating assets and liabilities:
        Accounts receivable ..............................       (84,562)         (79,988)           1,052             2,557
        Prepaid expenses and other .......................      (174,996)        (108,566)         (46,678)           (5,206)
        Intangibles ......................................      (431,690)          (4,353)         (44,314)          (66,152)
        Accounts payable .................................       315,373          101,849          (91,433)          164,744
        Accrued expenses .................................       863,350           84,790          449,244            50,512
                                                            -------------    -------------    -------------     -------------  
            Net cash used for operating activities .......    (9,954,310)      (4,126,684)      (2,709,491)       (1,059,467) 
                                                            -------------    -------------    -------------     -------------

CASH FLOWS FROM INVESTING ACTIVITIES:
  Purchases of property and equipment ....................      (614,934)        (279,705)         (26,577)           (4,294)
                                                            -------------    -------------    -------------     -------------
CASH FLOWS FROM FINANCING ACTIVITIES:
  Proceeds from notes payable, related party .............       302,000                -                -           302,000
  Payments on notes payable, related party ...............      (309,936)               -          (23,286)         (286,650)
  Proceeds from senior bridge notes payable ..............     1,850,000                -          850,000         1,000,000
  Payments on senior bridge notes ........................    (1,850,000)      (1,000,000)        (850,000)                -
  Proceeds from notes payable and
    long-term financing ..................................     1,951,327                -                -           292,063
  Payments on notes payable and
    long-term financing ..................................      (420,236)        (230,175)         (65,000)          (92,384)
  Proceeds from paid-in capital from common
    stock warrants .......................................       100,000                -                -           100,000
  Proceeds from common stock, stock option
    issuances, net .......................................    10,117,442           14,950        9,143,303               345
  Proceeds from preferred stock, net .....................    11,637,031       11,637,031
  Purchase of treasury stock .............................        (1,667)               -           (1,667)                -
                                                            -------------    -------------    -------------     -------------

            Net cash provided by financing activities ....    23,375,961       10,421,806        9,053,350         1,315,374
                                                            -------------    -------------    -------------     -------------

NET INCREASE IN CASH AND
     CASH EQUIVALENTS ....................................    12,806,717        6,015,417        6,317,282           251,613

CASH AND CASH EQUIVALENTS, beginning
     of period ...........................................             -        6,791,300          474,018           222,405
                                                            -------------    -------------    -------------     -------------

CASH AND CASH EQUIVALENTS, end of period .................  $ 12,806,717     $ 12,806,717     $  6,791,300      $    474,018
                                                            =============    =============    =============     =============

</TABLE>


The accompanying notes to consolidated financial statements are an integral part
of these statements.


                                      F-6

<PAGE>


                           PALATIN TECHNOLOGIES, INC.
                        (A Development Stage Enterprise)
                      Consolidated Statements of Cash Flows



<TABLE>
<CAPTION>


                                                                  Inception
                                                              (January 28, 1986)       Year         Ten Months           Year
                                                                   through            Ended            Ended            Ended
                                                                June 30, 1997      June 30, 1997   June 30, 1996   August 31, 1995
                                                              -----------------   --------------   -------------   ---------------
<S>                                                              <C>              <C>             <C>              <C>    

SUPPLEMENTAL CASH FLOW INFORMATION:
   Cash paid for interest .................................      $      229,522   $     151,999   $      49,494    $       28,029
                                                                 ==============   =============   =============    ==============
NON-CASH TRANSACTION:
   Settlement of accounts payable with
      equipment ...........................................      $          900   $           -   $           -    $            -
                                                                 ==============   =============   =============    ==============

NON-CASH STOCK ACTIVITY:
   Conversion of loans from employees to
      common stock ........................................      $       74,187   $           -   $           -    $            -
                                                                 ==============   =============   =============    ==============
   Conversion of note payable to common stock..............      $       16,000   $           -   $                $            -
                                                                 ==============   =============   =============    ==============
   Common stock issued for equipment ......................      $        2,327   $           -   $           -    $            -
                                                                 ==============   =============   =============    ==============
   Common stock issued for expenses
      (included above) ....................................      $      679,715   $     394,383   $      174,147   $       10,350
                                                                 ==============   =============   ==============   ==============
   Common stock issued for accrued salaries
      and bonuses .........................................      $       16,548   $               $            -   $        9,858
                                                                 ==============   =============   ==============   ==============
   Interest paid in common stock ..........................      $      679,097   $      303,171  $      266,743   $      109,183
                                                                 ==============   =============   ==============   ==============
</TABLE>























The accompanying notes to consolidated financial statements are an integral part
of these statements.

                                      F-7



<PAGE>


                           PALATIN TECHNOLOGIES, INC.
                        (A Development Stage Enterprise)
                   Notes to Consolidated Financial Statements

(1)     ORGANIZATION ACTIVITIES:

        Nature of  Business  -- Palatin  Technologies,  Inc.  ("Palatin"  or the
"Company") and its wholly-owned subsidiary, RhoMed Incorporated ("RhoMed"), is a
development  stage  enterprise   dedicated  to  developing  and  commercializing
products and  technologies  for diagnostic  imaging,  cancer therapy and ethical
drug development utilizing peptide,  monoclonal antibody and radiopharmaceutical
technologies.  On June 25, 1996,  RhoMed  merged into  Palatin in a  transaction
accounted  for as a reverse  merger,  with  RhoMed  deemed as the  acquiror  for
account purposes (see Corporate History).  As a result, the historical financial
statements presented are those of RhoMed.

        Business  Risk  --  Since  its   inception,   the  Company  has  devoted
substantially  all of its efforts and resources to the research and  development
of its technologies.  The Company has experienced  operating losses in each year
since  its  inception  and,  as of June 30,  1997,  the  Company  had a  deficit
accumulated during the development stage of $13,433,102.  The Company expects to
incur  additional  operating  losses  over the next  several  years and  expects
cumulative  losses to increase as research and development and clinical  testing
efforts  continue  and  expand.   The  ultimate   completion  of  the  Company's
development  projects  is  contingent  upon a number of factors,  including  the
successful completion of technology and product development,  obtaining required
regulatory  approvals  and  additional  financing  and,  ultimately,   achieving
profitable operations.

        Corporate History -- Palatin, formerly Interfilm, Inc., was incorporated
under the laws of the State of Delaware on November 21, 1986.  From  November 4,
1993 until May 10, 1995, the date on which the Board of Directors  substantially
curtailed the operations of the Company,  the Company had been primarily engaged
in the business of exploiting  rights related to its interactive  motion picture
process,  including  the  production  and  distribution  of  interactive  motion
pictures  for  initial  exhibition  in  theaters  and  subsequently  in enhanced
versions for distribution to the home market.  On June 25, 1996, a newly formed,
wholly-owned  subsidiary  of  the  Company,  Interfilm  Acquisition  Corporation
("InSub"),  a New Mexico corporation,  merged with and into RhoMed, a New Mexico
corporation,  with all outstanding shares of RhoMed equity securities ultimately
being exchanged for the Company's  common stock (the  "Merger").  As a result of
the Merger,  RhoMed became a  wholly-owned  subsidiary of the Company,  with the
holders of RhoMed preferred stock and RhoMed common stock (including the holders
of  "RhoMed   Securities"  as  hereafter  defined)  receiving  an  aggregate  of
approximately  96%  interest  in  the  equity  securities  of the  Company  on a
fully-diluted basis.  Additionally,  all warrants and options to purchase common
stock of  RhoMed  outstanding  immediately  prior  to the  Merger  (the  "RhoMed
Securities"),  including  without  limitation,  any rights  underlying  RhoMed's
qualified or non-qualified stock option plans, were automatically converted into
rights upon exercise to receive the Company's common stock in the same manner in
which  the  shares of RhoMed  common  stock  were  converted.  Since the  former
stockholders  of RhoMed  retained  more than a 50%  controlling  interest in the
surviving company  (Palatin),  the Merger was accounted for as a reverse merger.
The business of RhoMed, conducted by Palatin since June 25, 1996, represents the
on-going business of Palatin.  Certain assets and liabilities of the Company and
a subsidiary  existing  prior to the Merger,  consisting  principally of certain
intellectual  property and litigation claims against Sony Corporation of America
and related  entities,  were  transferred to an unaffiliated  limited  liability
partnership  for the benefit of the Company's  stockholders of record as of June
21, 1996 (pre-Merger stockholders). The historical

                                       F-8

<PAGE>



financial  statements  prior to June 25, 1996, are those of RhoMed,  except that
the stock  transactions  have been  presented in the notes on an as if converted
basis.  References  to the  Company's  activities,  results  of  operations  and
financial  condition  prior to June  25,  1996 are to  RhoMed  unless  otherwise
specified.  The merger costs of $525,000 have been charged to operations for the
ten months ended June 30, 1996,  and accrued  expenses  include  $32,000 of this
amount as of June 30, 1997.

        Charter  Amendment -- On September 5, 1997, an amendment to the Restated
Certificate of Incorporation of the Company (the  "Amendment") was filed,  which
(i) increased the total number of authorized shares of common stock (the "Common
Stock")  from  25,000,000  to  75,000,000,  (ii)  increased  the total number of
authorized  shares of preferred  stock from  2,000,000 to  10,000,000  and (iii)
effected a 1-for-4  reverse split of Common Stock.  The  consolidated  financial
statements have been retroactively restated to reflect the Amendment.

(2)     SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES:

        Principles of  Consolidation -- The  consolidated  financial  statements
include the accounts of Palatin and its wholly  owned  subsidiary,  RhoMed.  The
remaining  subsidiaries  of  Palatin -  Interfilm  Technologies,  Inc.,  Ediflex
Digital Systems,  Inc. and Production Equipment Leasing Corp. LP - are inactive.
All significant  intercompany  accounts and transactions have been eliminated in
consolidation.

        Use of Estimates -- The preparation of consolidated financial statements
in conformity with generally accepted accounting  principles requires management
to make estimates and assumptions  that affect the reported amount of assets and
liabilities  and disclosure of contingent  assets and liabilities at the date of
the consolidated  financial  statements and the reported amounts of revenues and
expenses  during the reporting  period.  Actual  results could differ from those
estimates.

        Fiscal Year -- Effective June 30, 1996,  Palatin and RhoMed each changed
its fiscal year end to June 30. The fiscal year ends of Palatin and RhoMed prior
to the Merger were December 31 and August 31, respectively.

        Cash and Cash  Equivalents -- For purposes of presenting cash flows, the
Company  considers  cash and cash  equivalents as amounts on hand, on deposit in
financial  institutions and highly liquid investments purchased with an original
maturity of three months or less.

        Fixed Assets -- Fixed assets consist of equipment,  office furniture and
leasehold  improvements.  Fixed  assets  are  stated  at cost.  Depreciation  is
recognized using the  straight-line  method over the estimated useful lives of 5
years for equipment, 7 years for office furniture and over the term of the lease
for  leasehold  improvements.  Maintenance  and repairs are expensed as incurred
while expenditures that extend the useful life of an asset are capitalized.

        Intangible  Assets -- Intangible  assets consist of patents and deferred
financing costs.  Patents represent the costs capitalized to successfully obtain
a patent  registration.  Internal  costs to obtain and develop the patents  have
been  expensed.  Patents are included as intangible  assets in the  accompanying
consolidated  financial  statements  and are stated at cost,  net of accumulated
amortization. Amortization is recognized using the straight-line method over the
estimated  patent lives  ranging up to 17 years.  Unsuccessful  patent costs and
patents with no  demonstrated  future value are expensed  when so  determined by
management.

        Impairment of Long-Lived  Assets -- The Company  complies with Statement
of Financial  Accounting  Standards No. 121,  "Accounting  for the Impairment of
Long-Lived  Assets and for  Long-Lived  Assets to Be  Disposed  Of." The Company
reviews  its  long-lived  assets for  impairment  whenever  events or changes in
circumstances  indicate that the carrying  amount of the assets may not be fully
recoverable. To determine

                                       F-9

<PAGE>



recoverability of its long-lived  assets,  the Company evaluates the probability
that future undiscounted net cash flows, without interest charges,  will be less
than the carrying amount of the assets. Impairment is measured at fair value.

        Revenue  Recognition  -- The  Company  recognizes  revenue on grants and
contracts at the time such related  expenses  are  incurred in  compliance  with
contractual  terms,  license  fees and  royalties  ratably  over the term of the
license or royalty agreement, and sales upon shipment.

        Research and Development  Costs -- The costs of research and development
activities are expensed as incurred.

        Stock  Options and Warrants -- Warrants and the majority of common stock
options have been issued at exercise  prices  greater  than,  or equal to, their
fair market value at the date granted.  Accordingly,  no value has been assigned
to these instruments.  However, certain stock options were issued under non-plan
option  agreements  and a  non-qualified  stock option plan at an exercise price
below market value.  The  difference  between the exercise  price and the market
value of these  securities  has been  recorded as deferred  compensation  and is
being expensed over the vesting period of the option.

        Income  Taxes  -- The  Company  and  its  subsidiaries  intend  to  file
consolidated federal and combined state income tax returns. The Company accounts
for income taxes in accordance with Statement of Financial  Accounting Standards
No. 109 ("SFAS 109"),  "Accounting  for Income Taxes." SFAS 109 requires,  among
other  things,  the use of the  liability  method in computing  deferred  income
taxes.

        The  Company  provides  for  deferred  income  taxes  relating to timing
differences in the recognition of income and expense items  (primarily  relating
to  depreciation,  amortization  and  certain  leases)  for  financial  and  tax
reporting  purposes.  Such  amounts  are  measured  using  current  tax laws and
regulations in accordance with the provisions of SFAS 109.

        In  accordance  with  SFAS  109,  the  Company  has  recorded  valuation
allowances  against the  realization  of its deferred tax assets.  The valuation
allowance is based on  management's  estimates and analysis,  which includes tax
laws  which  may  limit  the   Company's   ability  to  utilize   its  tax  loss
carryforwards.

        Net Loss per  Common  Share -- Net loss per common  share is  calculated
based upon the weighted  average  number of shares of Common Stock,  on an as if
converted basis,  outstanding  during each period. All options and warrants were
excluded in the calculation of weighted average shares  outstanding  since their
inclusion would have had an anti-dilutive effect.

        Reclassifications  --  Certain  reclassifications  have been made to the
prior year financial statements to conform to the current year presentation.

        Fair Value of Financial Instruments -- Statement of Financial Accounting
Standards  No.  107 ("SFAS  107"),  "Disclosures  about Fair Value of  Financial
Instruments,"  requires  disclosures of fair value  information  about financial
instruments,  whether or not  recognized in the balance  sheet,  for which it is
practicable  to estimate the value.  In cases where quoted market prices are not
available,  fair  values are based on  estimates  using  present  value or other
valuation  techniques.  These  techniques  are  significantly  affected  by  the
assumptions used, including discount rate and estimates of future cash flows. In
that  regard,  the  derived  fair value  estimates  cannot be  substantiated  by
comparison to independent  markets and, in many cases,  could not be realized in
immediate  settlement of the  instrument.  SFAS 107 excludes  certain  financial
instruments and all non-financial  instruments from its disclosure requirements.
Accordingly,  the aggregate  fair value  amounts  presented do not represent the
underlying value of the Company.

                                      F-10

<PAGE>



        The  following  methods  and  assumptions  were used by the  Company  in
estimating its fair value  disclosures for financial  instruments:  the carrying
amount  reported  on the  balance  sheet  approximates  the fair value for cash,
short-term  borrowings  and current  maturities of long-term  debt; and the fair
value for the  Company's  fixed rate  long-term  debt is estimated  based on the
current rates offered to the Company for debt of the same remaining  maturities.
Based on the above,  the amount reported on the balance sheet  approximates  the
fair value.

(3)     RELATED PARTY TRANSACTIONS:

        During the fiscal year ended  August 31, 1995,  the Company  encountered
serious liquidity and working capital deficiencies. As a result, effective April
1995,  the Company  entered  into a letter of intent with The Castle  Group Ltd.
("Castle"),   a  company   controlled  by  Lindsay  A.  Rosenwald,   M.D.  ("Dr.
Rosenwald"),  under which Castle agreed to arrange for a line of credit of up to
$300,000 to finance ongoing operations; agreed to arrange for future financings;
and  the  Company  agreed  to  sell  to  Castle  or its  designees,  for  $4,000
consideration  paid,  4,000,000  shares of preferred  stock which converted into
466,952  shares of Common  Stock.  At the time the letter of intent was  entered
into with Castle,  the Company was insolvent  and its equity had nominal  value;
accordingly, the sale of preferred stock to Castle or its designees was recorded
at the nominal $4,000 consideration paid. The issuance of the preferred stock to
designees  of Castle was  consummated  on October 25,  1995 and  resulted in Dr.
Rosenwald  and his  designees  obtaining  majority  ownership and control of the
Company on that date.

        On July 28, 1995, the Board of Directors  approved an offering of senior
bridge notes and warrants (the "Class A Offering"), for which Paramount Capital,
Inc. ("Paramount"),  of which Dr. Rosenwald is the Chairman, served as placement
agent.  Two of the then three  members of the Board of  Directors of RhoMed were
employees of entities controlled by Dr. Rosenwald. The transaction and selection
of the placement agent was ratified by disinterested  stockholders on August 15,
1995. Paramount received (i) a cash commission equal to 6% of the gross proceeds
from the sale of the units or $60,000, (ii) a non-accountable  expense allowance
equal to 3% of gross proceeds or $30,000 and (iii) placement  agent's  warrants,
on the same terms as the warrants,  equal to 15% of the Common Stock  underlying
the  warrants  issued in the Class A Offering.  Additionally,  investment  funds
managed by a company of which Dr. Rosenwald is president purchased senior bridge
notes with a face value of $100,000  and warrants to purchase  13,824  shares of
Common Stock at $.22 per share.

        On November  27, 1995,  the  Company's  Board of  Directors  approved an
offering of senior bridge notes and warrants (the "Class B Offering"), for which
Paramount served as placement agent, which was approved by the two disinterested
directors.  Paramount  received (i) a cash  commission  equal to 9% of the gross
proceeds from the sale of the units or $76,500,  (ii) a non-accountable  expense
allowance equal to 4% of gross proceeds or $34,000 and (iii)  placement  agent's
warrants at an exercise price of $6.52 per share but otherwise on the same terms
as the warrants,  equal to 5% of the Common Stock underlying the warrants issued
in the Class B Offering. Additionally,  investment funds managed by a company of
which Dr. Rosenwald is president purchased senior bridge notes with a face value
of $100,000 and  warrants to purchase  4,608 shares of Common Stock at $2.72 per
share.

        On March 4, 1996, the Board of Directors  approved an offering of common
stock (the "Common Stock Offering") and authorized an offering  committee of the
Board of Directors,  consisting of the two disinterested directors, to determine
the placement agent for the Common Stock Offering. The selection of Paramount as
placement agent was approved by the disinterested  directors, who concluded that
alternative  means of financings were not available to the Company on terms more
favorable than the Common Stock Offering. The price per share of common stock in
the Common Stock Offering of $5.44

                                      F-11

<PAGE>



was determined through  negotiations  between the Company and Paramount.  On May
14, 1996, the disinterested  directors  approved an increase in the Common Stock
Offering.  Paramount  received  (i) a cash  commission  equal to 9% of the gross
proceeds from the sale of the units or $868,000,  (ii) a non-accountable expense
allowance equal to 4% of gross proceeds or $386,000 and (iii) placement  agent's
warrants,  equal to 10% of the common stock issued in the Common Stock Offering,
at an  exercise  price of  $6.52  per  common  stock  share,  which  are  freely
exercisable,  terminate  ten years from the date of  issuance  and have  certain
registration rights. Additionally investment funds managed by a company of which
Dr. Rosenwald is president purchased 322,674 shares of Common Stock at $5.44 per
share.

               On December 2, 1996, the Board of Directors  approved an offering
of Series A Preferred  Convertible  Stock (the  "Series A Preferred  Offering"),
which  was  approved  by the four  disinterested  directors.  The  selection  of
Paramount as placement agent was approved by the  disinterested  directors,  who
concluded that alternative means of financings were not available to the Company
on terms more  favorable  than the  Series A  Preferred  Offering.  The Series A
Preferred  Convertible  Stock is  currently  convertible  into Common Stock at a
price per share of Common Stock of $4.96,  which  represented  a 15% discount to
the average closing bid price of the Company's  Common Stock for the twenty (20)
consecutive  trading  days  immediately  preceding  the final  closing.  The 15%
discount on  conversion  of the Series A Preferred  Convertible  Stock to Common
Stock was determined through  negotiations between the Company and the placement
agent.  The 15%  discount  has  been  reflected  in the  Company's  consolidated
statement  of  operations  as a dividend to the Series A  Preferred  Convertible
Stock of $2,888,935. Paramount received (i) a cash commission equal to 9% of the
gross proceeds from the sale of the units or $1,240,020,  (ii) a non-accountable
expense  allowance equal to 4% of gross proceeds or $551,120 and (iii) placement
agent's  warrants,  equal to 10% of the  Series A  Preferred  Convertible  Stock
issued in the Series A Preferred  Offering  at an exercise  price of $110.00 per
share of Series A  Preferred  Convertible  Stock,  which are freely  exercisable
commencing in November,  1997, terminate ten years from the date of issuance and
have  certain  registration  rights.  The Company has valued  those  warrants at
$573,537.  In the Series A Preferred  Offering,  investment  funds  managed by a
company of which Dr. Rosenwald is president  purchased 10,000 shares of Series A
Preferred Convertible Stock at $100 per share.

        Management of the Company  believes  that the terms of the  transactions
and the agreements  described  above are on terms at least as favorable as those
which it could otherwise have obtained from unrelated parties.

(4)     PROPERTY AND EQUIPMENT:

        Property and equipment consists of the following:


                                               June 30,             June 30,
                                                 1997                 1996
                                             ------------         ------------
Office equipment                             $    263,827         $    202,960
Laboratory equipment                              145,310               76,929
Leasehold improvements                            750,008                    -
                                             ------------         ------------
                                                1,159,145              279,889
Less: Accumulated depreciation                    237,049              183,535
                                             ------------         ------------
                                             $    922,096         $     96,354
                                             ============         ============


                                      F-12

<PAGE>



(5)     INTANGIBLES:

        The Company owns or has rights to sixteen  U.S. patents,  eight  pending
U.S.  patent  applications,  four  allowed  U.S.  patent  applications  and nine
counterpart   patents  and  eight  pending   applications  in  selected  foreign
countries.

        For the ten month  period ended June 30,  1996,  $259,334 of  previously
capitalized  patent costs  relating to patents that were not being  utilized for
products in active  development were written- off to expense.  The write-off was
based upon an evaluation by the new  President and Chief  Executive  Officer and
the  management  team  of  products  in  development  and  determination  of the
likelihood of product  development and  commercialization.  Historical  costs in
each patent were used to determine the total write-off to expense.

        The  Company has  assigned  its  interest  in several  patents to secure
long-term financing.

(6)     LONG-TERM FINANCING:

        The Company has a long-term  financing  agreement  with Aberlyn  Holding
Co., Inc., and its affiliates (collectively "Aberlyn"). Aberlyn has, in a series
of  transactions,  loaned to the Company  approximately  $1,800,000,  secured by
certain of the Company's patents,  intellectual property and equipment.  Certain
fees and costs related to the borrowings have been deferred as intangible assets
and are being amortized over the remaining  terms of the  arrangement  using the
effective interest method.

        The Company is obligated to make monthly principal and interest payments
of $91,695 from June 1, 1997 through May 1, 1999.  Payments of $20,000 per month
through May 1, 1997 were  applied to  principal  only;  with  interest  accruing
during  this  period  at an  annual  effective  rate of 15% and  payable  in the
Company's  Common Stock.  On June 24, 1996,  the Company issued an equivalent of
42,858 shares of Common Stock in payment of accrued interest of $324,546 through
April 30, 1996. In addition,  certain  warrants held by Aberlyn were terminated.
On May 15, 1997 the Company  issued  63,910 shares of Common Stock in payment of
accrued interest of $303,171 through April 30, 1997 at an immaterial discount of
approximately  $1.00 per share  under the then fair  market  value of the Common
Stock.

        Scheduled  principal  payments on the  long-term  financing  at June 30,
1997, are as follows:


              Fiscal Year
              -----------
                  1998                                       $869,549
                  1999                                        939,590
                                                          -----------
                                                          $ 1,809,139


(7)     SENIOR BRIDGE NOTES:

        Class A Offering -- On July 28, 1995, the Company  initiated the Class A
Offering of 40 units,  with each unit consisting of a $25,000 face amount senior
bridge  note and a warrant  to  purchase  3,456  shares  of  Common  Stock at an
exercise price of $.22 per share. All units were purchased, with net proceeds to
the Company of  approximately  $907,000  after payment of the placement  agent's
commissions and expenses ($90,000) and offering expenses (approximately $3,000).
The nominal  exercise  price for the warrants  reflected the seriously  troubled
financial  condition  of  the  Company  on the  date  of  the  transaction,  and
accordingly,  no value was assigned to the warrants  upon  issuance.  The senior
bridge notes sold in the Class A Offering  accrued interest at 1% per month, and
were payable,  with interest,  one year from the date of issuance. In August and
September of 1996, the Class A Offering notes with accrued interest were repaid

                                      F-13

<PAGE>



in full. The warrants are exercisable at any time,  terminate ten years from the
date of issuance, and have certain registration rights.

        Class B Offering -- On November  27,  1995,  the Company  initiated  the
Class B Offering of up to 7.5 units at $100,000 per unit, subsequently increased
to 8.5 units,  with each unit consisting of a $100,000 face amount senior bridge
note and a warrant to purchase an  equivalent of 4,608 shares of common stock at
an exercise  price of $2.72.  Net  proceeds to the Company were  $739,500  after
payment of the placement agent's commissions and expenses ($110,500). Due to the
seriously  troubled  financial  condition  of the  Company  on the  date  of the
transaction,  no value was assigned to the warrants  upon  issuance.  The senior
bridge notes sold in the Class B Offering  accrued interest at 1% per month, and
were  payable,  with  interest  12  months  from  the date of  issuance,  unless
accelerated under certain circumstances.  On June 28, 1996, the Class B Offering
notes with accrued  interest were paid in full. The warrants are  exercisable at
any  time,  terminate  five  years  from  the  date of  issuance,  have  certain
registration rights, and contain a call provision.

(8)     NOTES PAYABLE

        Notes payable  consist of four ten year notes  totaling  $80,000.  These
notes  were  issued as part of a  combined  stock and debt  offering  during the
fiscal year ended  August 31, 1992.  Each note is a promissory  note in the face
amount  of  $20,000,  bearing  interest  at 10%  per  year,  accruing  annually.
Principal and interest on the notes is due and payable by December 31, 1997.

(9)     COMMITMENTS AND CONTINGENCIES:

        Leases  --  The  Company  leases  two  facilities  in New  Jersey  under
noncancellable  operating leases.  Future minimum lease payments under those two
leases are as follows:


       Fiscal Year
       -----------
       1998                                  $   212,000
       1999                                      216,000
       2000                                      223,000
       2001                                      253,000
       2002                                      255,330
       2003 and therafter                      1,022,388


        Restructuring  Charge -- In conjunction  with the Company's  decision to
consolidate and relocate its research and  development  facilities and executive
offices from New Mexico to New Jersey,  the Company  established a restructuring
charge of $284,000.  The  restructuring  charge  represents  severance  costs of
$115,000  and  facility  closing   expenses  of  $169,000.   Five  research  and
development  and three  administrative  employees  were  severed  as part of the
relocation.  Facility  closing  expenses  consist  primarily of costs related to
lease  termination and fixed asset  disposals.  Included in accrued  expenses at
June 30, 1997, is $144,316 of remaining restructuring charges.

        Employment Agreements -- On November 27, 1996, the Board of Directors of
the Company ratified an employment  agreement (the "Employment  Agreement") with
Edward J.  Quilty  ("Mr.  Quilty")  to serve as  President  and Chief  Executive
Officer,  originally  entered into with RhoMed prior to the Merger.  Pursuant to
the Employment Agreement, RhoMed agreed to grant Mr. Quilty an option to acquire
such  number  of shares of  common  stock as equal a 10%  fully  diluted  equity
interest  in the Company at an exercise  price of $.22 per share,  which  option
vests in 36 equal increments on each of the first 36 monthly

                                      F-14

<PAGE>



anniversaries of the  commencement of Mr. Quilty's  employment with the Company,
and may be  accelerated or terminated in part on the happening of certain events
(the  "Initial   Option").   The  Employment   Agreement  further  provides  for
anti-dilution  options,  pursuant to which Mr. Quilty will be issued  options to
acquire the number of shares  that,  when  aggregated  with the shares  issuable
pursuant  to the  Initial  Option,  equal not less than  3.75% of the  shares of
common stock of the Company.  The Employment  Agreement is for an initial period
of one year, with automatic one year  extensions,  and provides that, on certain
termination  events,  the  portion  of the  options  that would  otherwise  have
terminated without vesting, vest and are exercisable upon termination,  and also
provides for specified termination pay.

        On September 27, 1996,  the Board of Directors  ratified two  employment
agreements  with two of the officers of the Company.  The  agreements  expire in
June 1999 and provide for current  annual  salaries of $160,500.  The agreements
include specified termination pay and accelerated vesting of stock options under
certain termination events.

        Consulting  Agreements -- The Company is obligated  under two consulting
agreements to make payments totaling $76,500 in fiscal 1998.

        License  Agreements  -- The  Company has two  license  agreements  which
require  minium  yearly  payments.  Future  minium  payments  under the  license
agreements are as follows:  1998 - $100,000,  1999 - $100,000,  2000-  $125,000,
2001 - $50,000 and 2002 - $50,000.

        Construction  -- The Company is  currently  constructing  a research and
development  facility in Edison,  New  Jersey.  The  Company is  committed  to a
construction  contract  for  approximately  $666,000  as of June 30,  1997.  The
remaining  services  under such  contract are expected to be completed in fiscal
1998.

        Legal  Proceedings  -- The  Company is  subject  to  various  claims and
litigation in the ordinary course of its business.  Management believes that the
outcome of such legal proceedings will not have a material adverse effect on the
Company's financial position or future results of operation.

(10)    STOCKHOLDERS' EQUITY (DEFICIT):

        The Company's Authorized Shares -- The Amendment, effective September 5,
1997,  increased the number of shares of authorized  Common Stock to 75,000,000,
increased the number of shares of authorized preferred stock to 10,000,000,  and
effected a 1-for-4 reverse split of the Common Stock. The consolidated financial
statements have been retroactively restated to reflect the Amendment.

        Preferred  Stock  Transactions  -- On  December  2,  1996,  the  Company
commenced  the Series A Preferred  Offering of units at a price of $100,000  per
unit,  each unit  consisting of 1,000 shares of Series A  Convertible  Preferred
Stock. The final closing on the Series A Preferred  Offering was effective as of
May 9, 1997,  with the Company  having sold an aggregate  total of 137.78 units,
representing  137,780 shares of Series A Convertible  Preferred  Stock,  for net
proceeds to the Company of approximately $11,637,000, after deducting commission
and other expenses of the Series A Preferred Offering.

        Optional Conversion.  Each share of Series A Convertible Preferred Stock
is  convertible  at any time,  at the option of the  holder,  into the number of
shares of Common  Stock equal to $100  divided by the  "Conversion  Price".  The
current  Conversion  Price  is  $4.96,  so each  share of  Series A  Convertible
Preferred  Stock is  currently  convertible  into  approximately  20.2 shares of
Common Stock. The Conversion Price is subject to adjustment.

        Mandatory Conversion.  Commencing May 9, 1998, the  Company may,  at its
option,  cause the conversion of the Series A Convertible  Preferred  Stock,  in
whole or in part, on a pro rata basis, into

                                      F-15

<PAGE>



Common Stock at the  conversion  rate in effect at that time, if the closing bid
price of the Common Stock has exceeded  200% of the then  applicable  Conversion
Price for at least  twenty  (20)  trading  days in any thirty  (30)  consecutive
trading day period ending three (3) days prior to the date of conversion.

        Adjustments to the Conversion  Price. The Conversion Price is subject to
adjustment,  under  certain  circumstances,  upon the sale or issuance of Common
Stock for  consideration  per share less than either (i) the Conversion Price in
effect on the date of such sale or  issuance,  or (ii) the  market  price of the
Common Stock as of the date of such sale or issuance.  The  Conversion  Price is
also subject to  adjustment  upon the  occurrence  of a merger,  reorganization,
consolidation, reclassification, stock dividend or stock split which will result
in an increase or decrease in the number of shares of Common Stock outstanding.

        Conversion  Price  Reset  Event.  The  Conversion  Price is  subject  to
adjustment on May 9, 1998 (the "Reset Date") if the average closing bid price of
the Common  Stock for the  thirty  (30)  consecutive  trading  days  immediately
preceding  the Reset Date (the "Reset  Trading  Price") is less than 130% of the
then  applicable  Conversion  Price (a "Reset Event").  Upon a Reset Event,  the
Conversion  Price will be reduced  to  greater  of (i) the Reset  Trading  Price
divided by 1.3 or (ii) 50% of the  Conversion  Price in effect  before the Reset
Event.

        Common Stock Transactions -- On March 4, 1996, the Company initiated the
Common Stock Offering of units at $100,000 per unit,  with each unit  consisting
of 18,433  shares of Common  Stock at a purchase  price of $5.44 per share.  The
Common Stock Offering was terminated on June 24, 1996,  with 96.454 units having
been sold, realizing net proceeds of approximately $8,391,000,  and resulting in
the issuance of 1,777,961 shares of Common Stock.

        On June 24, 1996, and pursuant to the Merger,  certain  stockholders  of
Interfilm  prior to the Merger and third  parties  purchased  138,249  shares of
Common  Stock at a  purchase  price of $5.44 per  share,  with net  proceeds  of
approximately  $748,000.  In addition,  and pursuant to the Merger,  warrants to
purchase 69,124 shares of Common Stock at an exercise price of $8.68 were issued
to certain  stockholders  of  Interfilm  prior to the Merger and third  parties.
These warrants are  exercisable at any time,  terminate four years from the date
of issuance,  have certain registration rights, contain a call provision and are
subject to adjustment in certain circumstances.

        In the ten months ended June 30, 1996,  the Company issued 31,492 shares
of Common Stock in exchange for services and recorded  compensation  expense for
the fair market value of the shares.

        The Company  commenced a private  offering of preferred  stock in fiscal
1994,  and a private  offering of units  consisting  of common  stock and common
stock  warrants in fiscal 1995,  both of which were  terminated  without  having
raised the minimum  required  for  closing.  Stock  issuance  costs  incurred in
connection with both offerings were expensed to operations in the fiscal year in
which such costs were incurred.

        In February 1993, the Company sold 26,912 shares of Common Stock for net
proceeds of approximately $577,000.

        In September  1992,  the Company sold 12,288  shares of Common Stock for
net proceeds of approximately $191,000.

        In December 1991, the Company issued a private  offering  memorandum for
the sale of units  consisting of 1,211 shares of Common Stock and a $20,000 note
(see Note 8). Four units were sold for $25,000 per unit.

                                      F-16

<PAGE>



        All  pre-Merger  common stock  issuances  were for RhoMed  common stock,
subsequently  converted  into the  Company's  Common  Stock  as a result  of the
Merger,  and were at issuance  prices  representing  market  value of the RhoMed
common stock on the date of issuance.

        Outstanding Stock Purchase Warrants -- At June 30, 1997, the Company had
the  following  warrants  outstanding,  all of which are  currently  exercisable
except 2,777 warrants included in "Other Warrants."

<TABLE>
<CAPTION>

                                             Common               Exercise Price                 Latest
         Warrant                         Stock Shares               per Share              Termination Date
- --------------------------              --------------           ---------------           ----------------
<S>                                     <C>                      <C>                       <C>  
Class A Offering                            114,055              $           .22                9/13/05
Class A Placement Agent                      20,737                          .22                9/13/05
Class B Offering                             39,170                         2.72                2/15/01
Class B Placement Agent                       1,958                         6.52                2/15/06
Common Stock Offering PlacementAgent        177,796                         6.52                6/25/06
Merger Warrants                              69,124                         8.68                6/24/00
Series A Preferred Offering
 Placement Agent                            277,782                         5.46                11/9/02
Other Warrants                               13,965              $9.00 - $282.00               12/12/06
                                        -----------              ---------------               --------
  Total                                     714,587              $ .22 - $282.00                6/25/06
                                        ===========              ===============               ========
</TABLE>

The Class B Offering  and  Merger  Warrants  contain  provisions  providing  for
termination  of the warrant if not exercised  following  notice of specified per
share trading prices.

        Stock Option Plans -- The Company has one stock option plan currently in
effect  under which  future  grants may be issued,  the 1996 Stock  Option Plan,
approved by the  Company's  stockholders  on August 25, 1997,  for which 625,000
shares of Common Stock are reserved.

        Prior to the Merger,  the  Company  had adopted a 1993 Equity  Incentive
Plan, pursuant to which options for 6,687 Common Stock shares,  giving effect to
the Merger and Amendment,  were granted and outstanding at June 30, 1997. No new
shares can be issued under this Plan.

        Pursuant to the Merger,  options which had been granted  under  RhoMed's
four stock option plans constituted  RhoMed Securities which were  automatically
converted  into rights upon exercise to receive  Common Stock in the same manner
in which the shares of RhoMed common stock were converted.

        In October  1995,  the  Financial  Accounting  Standards  Board  adopted
Statement of Financial  Accounting  Standards No. 123 ("SFAS 123"),  "Accounting
for Stock-Based  Compensation."  Effective July 1, 1996, the Company has elected
to adopt the disclosures of this  pronouncement.  Had compensation  cost for the
Company's  stock option plans been  determined  based upon the fair value at the
grant  date for  awards  under  SFAS 123,  the  Company's  net loss and net loss
attributable to common  stockholders per share for the ten months ended June 30,
1996 would have been $4,060,901 and $7.58, respectively,  while net loss and net
loss  attributable to common  stockholders per share for the year ended June 30,
1997 was  $5,695,856  and $2.94,  respectively.  Because  the SFAS 123 method of
accounting  has not been applied to options  granted prior to September 1, 1995,
the resulting pro forma  compensation cost, and thus pro forma net loss, may not
be  representative  of that to be expected in future years. The weighted average
fair market value at the date of grant for options  granted during 1996 and 1997
is estimated as $3.44 and $2.98 per

                                      F-17

<PAGE>



share,   respectively,   using  the  Black-Scholes   option-pricing  model.  The
assumptions used in the  Black-Scholes  model are as follows:  dividend yield of
0%, expected  volatility of 60%,  weighted  average  risk-free  interest rate of
6.37% in 1996 and 6.60% in 1997, and an expected option life of 7 years.

        The status of the plans,  including  predecessor and  replacement  plans
under  which  options  remain  outstanding,  giving  effect to the  Merger,  the
Amendment  and  stockholder  approval of the  Company's  1996 Stock Option Plan,
during the three years ended June 30, 1997, was as follows:

<TABLE>
<CAPTION>
                                                    Incentive Stock Options                     Nonqualified Stock Options
                                            ------------------------------------------    ---------------------------------------
                                                                             Weighted                                    Weighted
                                             Number                           average       Number                        average
                                               of             Price          price per        of            Price        price per
                                             shares         per share          share        shares        per share        share
                                           ----------   -----------------    ----------    --------   --------------     --------- 
<S>                                        <C>          <C>                  <C>          <C>         <C>                   <C>
Balance at inception                                -   $               -    $        -           -   $            -        $   -
    Granted                                    33,536        7.59 - 21.70                    57,583     6.51 - 21.70
    Terminated                                (3,248)               21.70                      (115)           21.70
                                           ----------   -----------------                 ----------  --------------
Outstanding, August 31, 1995                   30,288        7.59 - 21.70         16.72      57,468     6.51 - 21.70         11.69
    Granted                                   350,287          .22 - 5.42                    79,176       .22 - 5.42
    Interfilm, Inc. pre-Merger options          6,687     306.00 - 360.00                         -                -
    Terminated                                (8,928)        5.42 - 21.70                    (2,626)           21.70
                                           ----------   -----------------                 ---------   --------------
Outstanding, June 30, 1996                    378,334        .22 - 360.00         10.76     134,018      .22 - 21.70          8.21
    Granted                                    84,044         7.50 - 8.00                   100,905      5.44 - 8.00
    Terminated                               (54,958)                5.42                   (19,907)            5.42
    Exercised                                (47,918)                 .22                        -                 -
                                           ----------  ------------------                 ----------  --------------
Outstanding, June 30, 1997                    359,502        .22 - 360.00         12.26     215,016      .22 - 21.70          8.07
Exercisable, June 30, 1997                    148,392     $ .22 - $360.00        $23.14     146,028    $.22 - $21.70         $9.12
                                           ==========     ===============        ======    ========    =============         =====
</TABLE>


        In addition,  during the year ended June 30, 1997,  the Company  granted
anti-dilution  options to Mr.  Quilty  pursuant to his  Employment  Agreement to
purchase  152,799  shares  of  Common  Stock  at  $.20  per  share,  which  were
exercisable  as to  33,656  shares as of June 30,  1997,  and  granted  non-plan
options to three  executive  officers to purchase an aggregate of 110,807 shares
of Common Stock at $4.96 per share,  none of which were  exercisable  as of June
30, 1997. There were no other outstanding non-plan options.

(11)    GRANTS AND CONTRACTS:

        The Company  applies for and has received grants and contracts under the
Small Business  Innovative  Research ("SBIR") program and other federally funded
grant and contract programs.  Since inception,  approximately  $2,876,173 of the
Company's  revenues have been derived from  federally or state funded grants and
contracts.  Under federal grants and contracts,  there are no royalties or other
forms of repayment; however, in certain limited circumstances the government can
acquire rights to technology  which is not being  commercially  exploited.  Most
contract costs, including indirect costs, are subject to audit and adjustment by
negotiation with government representatives.

(12)    LICENSING FEES AND ROYALTIES:

        In December  1996,  the Company  entered into an Option  Agreement  with
Nihon Medi-Physics ("Nihon"), pursuant to which the Company received, in January
1997, an initial  payment of $1,000,000  before  Japanese  withholding  taxes of
$100,000  (the  "Initial  Payment").  The Company has  accounted for the Initial
Payment by recognizing  license fee revenue of $350,000 and deferred license fee
revenue of

                                      F-18

<PAGE>


$550,000.  The deferred license fee revenue will be recognized as revenue when a
license agreement is consummated. In the event that the parties can not agree on
terms of a license agreement, the Company could be required to repay $550,000 of
the initial payment back to Nihon. The agreement includes additional payments to
the Company upon the attainment of certain milestones.

(13)    INCOME TAXES:

        The Company has had no income  tax expense  or benefit  since  inception
because of operating losses.  Deferred tax assets and liabilities are determined
based on the estimated  future tax effect of  differences  between the financial
statements  and tax  reporting  basis  of  assets  and  liabilities,  given  the
provisions  of the tax laws.  A valuation  allowance  for the net  deferred  tax
assets has been recorded at June 30, 1997,  based on the weight of evidence that
the deferred tax assets exceed the likely  reversal of deferred tax  liabilities
and likely taxable income.

        The  Tax  Reform  Act of  1986  imposes  limitations  on the  use of net
operating loss  carryforwards  if certain stock  ownership  changes occur.  As a
result of the change in  majority  ownership  relating  to the Castle  preferred
stock  transaction,  the Common  Stock  Offering,  the Merger,  and the Series A
Preferred  Stock  Offering,  the  Company  most likely will not be able to fully
realize the benefit of its net operating loss carryforwards.

(14)    COMPARISON WITH THE YEAR ENDED JUNE 30, 1996:

        As noted  above,  the  Company  changed  its fiscal year end to June 30.
Therefore,  the following June 30, 1997 and 1996, selected financial information
is presented for comparative purposes only (unaudited):


                                                        Year Ended
                                                         June 30,
                                           -------------------------------------
                                                1997                    1996
                                           -------------           -------------
Revenues                                   $    722,357            $     27,517
Research and development expenses             3,409,983                 953,730
General and administrative expenses           2,533,883               1,633,598
Other income (expenses)                         (78,655)             (1,687,853)
                                           -------------           -------------
Net loss                                   $ (5,300,164)           $ (4,247,664)
                                           =============           =============
Weighted average number of
  common shares outstanding                   2,924,073                 540,216
                                           =============           =============
Net loss per common share                  $      (1.81)           $      (7.86)
                                           =============           =============


                                      F-19





                            CERTIFICATE OF AMENDMENT

                                     TO THE

                      RESTATED CERTIFICATE OF INCORPORATION

                                       OF

                           PALATIN TECHNOLOGIES, INC.
 

              -----------------------------------------------------


                            Under Section 242 of the
                             General Corporation Law
                            of the State of Delaware

              -----------------------------------------------------


     The  undersigned  officer  of  Palatin   Technologies,   Inc.,  a  Delaware
corporation (the  "Corporation"),  in order to amend the Restated Certificate of
Incorporation of the  Corporation,  pursuant to the provisions of Section 242 of
the General  Corporation  Law of the State of Delaware,  does hereby  certify as
follows:

     1. The Restated  Certificate of  Incorporation of the Corporation is hereby
amended by striking  out Section 1 of Article IV thereof in its  entirety and by
substituting in lieu of said Section 1 the following new Section 1:

          Section  1.  AUTHORIZED   CAPITAL  STOCK.  The  Corporation  shall  be
     authorized  to  issue  two  classes  of  shares  of  capital  stock  to  be
     designated,  respectively,  "Preferred Stock" and "Common Stock." The total
     number of shares of  capital  stock  which the  Corporation  shall have the
     authority to issue is 85,000,000,  comprised of 75,000,000 shares of Common
     Stock, par value $.01 per share, and 10,000,000  shares of Preferred Stock,
     par value $.01 per share.

     2. The Restated  Certificate of  Incorporation of the Corporation is hereby
amended by including a new Section 4 of Article IV thereof as follows:

          SECTION 4. Upon the date the Certificate of Amendment,  including this
     Section 4, is filed with the  Secretary  of State of the State of  Delaware
     (the "Effective  Date"),  each four shares of issued and outstanding shares
     of Common Stock of this Corporation  shall be  automatically  combined into
     one share of Common Stock of this  Corporation (the "Reverse Stock Split").
     In lieu of the issuance of any

                                     Page 1

<PAGE>

     fractional shares that would otherwise result from the Reverse Stock Split,
     the Corporation shall pay the cash value of fractions of a share determined
     by the average  closing  price of the Common Stock for the five (5) trading
     days immediately  preceding the Effective Date multiplied by the fractional
     interest.  Following  the Effective  Date,  certificates  representing  the
     shares of Common Stock to be outstanding  thereafter shall be exchanged for
     certificates  now  outstanding   pursuant  to  procedures  adopted  by  the
     Corporation's  Board of  Directors  and  communicated  to those  who are to
     receive new certificates.

     3. The foregoing  amendments to the Corporation's  Restated  Certificate of
Incorporation were duly authorized and adopted in accordance with the provisions
of Section 242 of the General Corporation Law of the State of Delaware.

     4. This Certificate of Amendment shall become effective at 11:59 p.m., EDT,
on September 5, 1997.

     IN  WITNESS  WHEREOF,  the  undersigned  has  signed  this  Certificate  of
Amendment and does hereby affirm, under penalty of perjury,  that the statements
contained herein are true and correct, this 5th day of September, 1997.

                                             Palatin Technologies, Inc.


                                                   /s/ John J. McDonough
                                             -----------------------------
                                             Name:  John J. McDonough
                                             Title: Vice President



                                     Page 2






                            LEASE AND LEASE AGREEMENT

                                     Between

                   CARNEGIE 214 ASSOCIATES LIMITED PARTNERSHIP

                                  The Landlord

                                       And

                           PALATIN TECHNOLOGIES, INC.

                                   The Tenant

                             For Leased Premises In

                               214 Carnegie Center

                              Princeton, New Jersey


                                   MAY 6, 1997









Prepared by:
Gary O. Turndorf
101 Carnegie Center
Suite 101
Princeton, NJ 08540
(609) 452-1444


<PAGE>



                                TABLE OF CONTENTS
<TABLE>

<CAPTION>
         Article                                                                                              Page
         -------                                                                                              ----        
<S>     <C>                                                                                             <C>


1.       Definitions                                                                                             1
2.       Lease of the Leased Premises                                                                            1
3.       Rent                                                                                                    1
4.       Term                                                                                                    2
5.       Preparation of the Leased Premises                                                                      3
6.       Options                                                                                                 3
7.       Use and Occupancy                                                                                       4
8.       Utilities, Services, Maintenance and Repairs                                                            6
9.       Allocation of the Expense of Utilities, Services, Maintenance, Repairs and Taxes                        7
10.      Computation and Payment of Allocated Expenses of Utilities, Services, Maintenance,                      8
         Repairs, Taxes and Capital Expenditures
11.      Leasehold Improvements, Fixtures and Trade Fixtures                                                    13
12.      Alterations, Improvements and Other Modifications by the Tenant                                        14
13.      Landlord's Rights of Entry and Access                                                                  15
14.      Liabilities and Insurance Obligations                                                                  16
15.      Casualty Damage to Building or Leased Premises                                                         18
16.      Condemnation                                                                                           19
17.      Assignment or Subletting by Tenant                                                                     20
18.      Signs, Displays and Advertising                                                                        22
19.      Quiet Enjoyment                                                                                        23
20.      Relocation                                                                                             23
21.      Surrender                                                                                              23
22.      Events of Default                                                                                      24
23.      Rights and Remedies                                                                                    25
24.      Termination of the Term                                                                                28
25.      Mortgage and Underlying Lease Priority                                                                 29
26.      Transfer by Landlord                                                                                   29

</TABLE>

                                      -ii-

<PAGE>


<TABLE>

<S>     <C>                                                                                                   <C>

27.      Indemnification                                                                                        30
28.      Parties' Liability                                                                                     31
29.      Security Deposit                                                                                       33
30.      Representations                                                                                        33
31.      Reservation in Favor of Tenant                                                                         34
32.      Tenant's Certificates and Mortgagee Notice Requirements                                                34
33.      Waiver of Jury Trial and Arbitration                                                                   36
34.      Severability                                                                                           36
35.      Notices                                                                                                36
36.      Captions                                                                                               36
37.      Counterparts                                                                                           36
38.      Applicable Law                                                                                         37
39.      Exclusive Benefit                                                                                      37
40.      Successors                                                                                             37
41.      Amendments                                                                                             37
42.      Waiver                                                                                                 37
43.      Course of Performance                                                                                  37

</TABLE>


                                TABLE OF EXHIBITS
Exhibit
Leased Premises Floor Space Diagram                                           A
Property Description                                                          B
Work Letter                                                                   C
Building Rules and Regulations                                                D
Definitions and Index of Definitions                                          E
Form of Estoppel Certificate                                                  F

                                      -iii-

<PAGE>



LEASE AND LEASE  AGREEMENT,  dated May 6, 1997,  between CARNEGIE 214 ASSOCIATES
LIMITED  PARTNERSHIP,  a New Jersey limited  partnership,  with offices at Suite
101, 101 Carnegie  Center,  Princeton,  New Jersey 08540 (the  "Landlord"),  and
PALATIN  TECHNOLOGIES,  INC.,  a  Delaware  corporation,  with an  office at 214
Carnegie Center, Princeton, NJ 08540 (the "Tenant").

Subject to all the terms and  conditions  set forth below,  the Landlord and the
Tenant hereby agree as follows:

1.       Definitions.

Certain terms and phrases used in this  Agreement  (generally  those whose first
letters are  capitalized)  are defined in Exhibit E attached hereto and, as used
in this Agreement,  they shall have the respective meanings assigned or referred
to in that exhibit.

2.       Lease of the Leased Premises.

2.1.     The  Landlord  shall,  and hereby  does,  lease to the Tenant,  and the
         Tenant shall, and hereby does, accept and lease from the Landlord,  the
         Leased Premises  during the Term. The Leased Premises  consist of 3,970
         square  feet of gross  rentable  floor  space on the first floor of 214
         Carnegie  Center,  as more fully  described in the definition of Leased
         Premises set forth in Exhibit E attached hereto.

2.2.     The  Landlord  shall,  and hereby  does,  grant to the Tenant,  and the
         Tenant  shall,  and  hereby  does,   accept  from  the  Landlord,   the
         non-exclusive  right to use the Common  Facilities  during the Term for
         itself,  its  employees,  other  agents and  Guests in common  with the
         Landlord, any tenants of Other Leased Premises, any of their respective
         employees,  other  agents  and  guests  and such  other  persons as the
         Landlord may, in the Landlord's sole discretion, determine from time to
         time.

3.       Rent.

3.1.     The Tenant shall  punctually  pay the Rent for the Leased  Premises for
         the Term to the  Landlord  in the  amounts  and at the  times set forth
         below,  without bill or other demand and without any offset,  deduction
         or,  except  as  may  be  otherwise  specifically  set  forth  in  this
         Agreement, abatement whatsoever.

3.2.     The Basic Rent for the Leased Premises during the Initial Term shall be
         at the rate per year set forth below:


      Years                  Annual Rate                       Monthly Rate
      -----                  ------ ----                       ------- ----
   1 through 5               $97,265.04                         $8,105.42


The annual rate of Basic Rent for the Leased  Premises  during any Renewal  Term
shall be  calculated as set forth in  subsection  6.3 of this  Agreement for the
respective Renewal Term.

3.3.     The Tenant  shall  punctually  pay the  applicable  Basic Rent in equal
         monthly  installments  in advance on the first day of each month during
         the Term,  with the exception of Basic Rent for the first full calendar
         month  of the  Initial  Term  and for any  period  of less  than a full
         calendar

                                       -1-

<PAGE>



         month at the beginning of the Term. The Tenant shall pay the Basic Rent
         for the first full  calendar  month of the Initial Term upon  execution
         and delivery of this  Agreement.  The Tenant shall  punctually  pay the
         Basic  Rent  for a period  of less  than a full  calendar  month at the
         beginning of the Term on the Commencement Date.

3.4.     The Basic  Rent and the  Additional  Rent for any period of less than a
         full  calendar  month  shall  be  prorated.   In  the  event  that  any
         installment  of Basic Rent cannot be  calculated by the time payment is
         due, such portion as is then known or calculable  shall be then due and
         payable; and the balance shall be due upon the Landlord's giving notice
         to the Tenant of the amount of the balance due.

3.5.     The Additional  Rent for the Leased  Premises  during the Term shall be
         promptly  paid  by the  Tenant  in the  respective  amounts  and at the
         respective times set forth in this Agreement.
                                
3.6.    That  portion  of any  amount of Rent or other  amount  due  under  this
        Agreement  which is not paid on the day it is first  due  shall  incur a
        late charge equal to the sum of: (i) five percent of that portion of any
        amount of Rent or other  amount  due under this  Agreement  which is not
        paid on the day it is first due and (ii) interest on that portion of any
        amount of Rent or other  amount  due under this  Agreement  which is not
        paid on the day it is first due at the Base  Rate(s) in effect from time
        to time plus two additional  percentage points from the day such portion
        is first due through  the day of receipt  thereof by the  Landlord.  Any
        such late charge due from the Tenant shall be due immediately.

4.       Term.

4.1.     The  Initial  Term shall  commence on the  Commencement  Date and shall
         continue for five years from the beginning of the Initial Year,  unless
         sooner terminated in accordance with section 24 of this Agreement.  The
         Term shall commence on the  Commencement  Date and shall continue until
         the later of the  conclusion  of the Initial Term or the  conclusion of
         any Renewal Term,  unless sooner  terminated in accordance with section
         24 of this Agreement.

4.2.     Unless one or more of the conditions  contemplated by subsection 4.3 of
         this Agreement occurs, the Commencement Date shall be the later of:

         4.2.1.   the Target Date; or

         4.2.2.   the  date  the  Landlord  can  deliver  actual  and  exclusive
                  possession of the Leased  Premises to the Tenant in accordance
                  with the provisions of Article 5 of this Agreement.

4.3.     In the  event  one or  more  of the  conditions  contemplated  by  this
         subsection 4.3 of the Agreement occurs, notwithstanding anything to the
         contrary  set  forth  in  subsection   4.2  of  this   Agreement,   the
         Commencement   Date  shall  be  the  earliest  date  the  Tenant  takes
         possession of, occupies or moves any furniture, furnishings,  equipment
         (with  the  exception  of  equipment  required  for  telecommunications
         hook-ups),  supplies or other  possessions into, the Leased Premises or
         any portion  thereof  earlier  than the date  otherwise  determined  in
         accordance with subsection 4.2 of this Agreement.



                                       -2-

<PAGE>



4.4.     Once it is ascertained in accordance  with  subsections  4.2 and 4.3 of
         this   Agreement,   the  Landlord  shall  give  prompt  notice  of  the
         Commencement  Date to the  Tenant;  and if the  Tenant  does not object
         thereto  by  notice  given  to  the  Landlord  within  10  days  of the
         Landlord's  notice,  the date set forth in the Landlord's  notice shall
         thereafter be conclusively presumed to be the Commencement Date.

5.       Preparation of the Leased Premises.

The  Landlord  shall  deliver  actual  and  exclusive  possession  of the Leased
Premises to the Tenant in an "AS-IS" condition, free of rubbish and debris.

6.       Options.

6.1.    If, prior to the respective  date of exercise  thereof,  (a)(i) no Event
        of Default shall have occurred or (ii) if an Event of Default shall have
        occurred,  the  Tenant  shall have  previously  cured it in full and the
        Landlord  shall  have  waived  it and (b)  there  shall  not have been a
        History  of  Recurring  Events of  Default,  the  Tenant  shall have one
        option,  exercisable exclusively at the time and in the manner set forth
        below in subsection  6.2 of this  Agreement,  to extend the Term for one
        additional  period of five  years'  duration.  If the option is properly
        exercised, the period to which it relates shall commence upon the end of
        the Expiring Term. The option is an "Option to Renew."

6.2.    In the event the  Tenant  is  interested  in  exercising  the  Option to
        Renew,  the Tenant shall give timely notice of the Tenant's  interest to
        the Landlord no earlier than nine, and no later than eight, months prior
        to the end of the Expiring Term. Within four weeks of the giving of such
        notice,  the  Landlord  shall  give  notice to the  Tenant of the Market
        Rental Rate in effect eight months prior to end of the Expiring Term. In
        the event the Tenant desires to exercise the Option to Renew, the Tenant
        shall do so  exclusively by giving timely notice thereof to the Landlord
        no earlier than seven, and no later than six, months prior to the end of
        the Expiring  Term,  and  indicating  in that notice  whether or not the
        Market  Rental  Rate in  effect  eight  months  prior  to the end of the
        Expiring  Term is  acceptable.  In the event the Tenant  fails timely to
        notify the Landlord of its interest in exercising the Option to Renew or
        timely to  exercise  the  Option to Renew,  that  Option to Renew  shall
        thereupon expire.

6.3.     The Basic Rent for the Leased Premises during the Renewal Term shall be
         the Market  Rental Rate, as set forth in the  Landlord's  notice to the
         Tenant of the Market  Rental Rate,  unless the Tenant,  in the Tenant's
         notice  contemplated  by the third  sentence of subsection  6.2 of this
         Agreement  affirmatively  indicates that the Market Rental Rate for the
         Renewal  Term is not  acceptable,  in which case the Basic Rent for the
         Leased Premises during the Renewal Term shall be the greater of:

         6.3.1.   that  amount  which is the product of the annual rate of Basic
                  Rent in effect  during the last 12 months of the Expiring Term
                  multiplied by the sum of the  following  two amounts:  (a) one
                  and (b) the amount  obtained  by  multiplying  five-hundredths
                  (.05) by the number of full  calendar  months in the  Expiring
                  Term and dividing the result by 12; or

                                       -3-

<PAGE>



         6.3.2.   that  amount  which bears the same ratio to the annual rate of
                  Basic Rent in effect during the Expiring Term as the Index for
                  the ninth month before the end of the  Expiring  Term bears to
                  the Index for the ninth month  before the first full  calendar
                  month at the beginning of the Expiring Term.

6.4.     In the event the Tenant assigns this Agreement or sublets,  or licenses
         the use or occupancy of, the Leased Premises or any portions thereof in
         accordance with section 17 of this Agreement or otherwise,  or attempts
         to do so:

         6.4.1.   any Option to Renew which the Tenant has theretofore  properly
                  exercised  with  respect  to a  Renewal  Term that has not yet
                  actually  commenced  shall be  rescinded,  if the  Landlord so
                  elects by notice to the  Tenant,  to the same  extent as if it
                  had not been exercised at all; and

         6.4.2.   any  Option to Renew or any other  type of option or  optional
                  right  exercisable  by the Tenant not  theretofore  timely and
                  otherwise  properly  exercised by the Tenant  shall  thereupon
                  expire.

7.       Use and Occupancy.

7.1.     The Tenant shall continuously occupy and use the Leased Premises during
         the Term exclusively as an office for its business of administering the
         off-site manufacture and sale of its medical supplies.

7.2.     In  connection  with  the  Tenant's  use and  occupancy  of the  Leased
         Premises and use of the Common  Facilities,  the Tenant shall  observe,
         and the Tenant  shall cause the  Tenant's  employees,  other agents and
         Guests to observe, each of the following:

         7.2.1.   the  Tenant  shall not do,  or permit or suffer  the doing of,
                  anything   which  might  have  the  effect  of  creating   not
                  insignificantly  increased  risk of,  or  damage  from,  fire,
                  explosion or other casualty;

         7.2.2.   the  Tenant  shall not do,  or permit or suffer  the doing of,
                  anything  which  would have the effect of (a)  increasing  any
                  premium  for  any  liability,  property,  casualty  or  excess
                  coverage insurance policy otherwise payable by the Landlord or
                  any  tenant of Other  Leased  Premises  or (b) making any such
                  types or amounts of  insurance  coverage  unavailable  or less
                  available  to the  Landlord  or any  tenant  of  Other  Leased
                  Premises;

         7.2.3.   to the extent they are not  inconsistent  with this Agreement,
                  the Tenant and the Tenant's employees, other agents and Guests
                  shall comply with the Building Rules and Regulations  attached
                  hereto as Exhibit D, and with any changes  made therein by the
                  Landlord  if, with respect to any such  changes,  the Landlord
                  shall  have  given  notice of the  particular  changes  to the
                  Tenant and such changes shall not materially  adversely affect
                  the conduct of the Tenant's business in the Leased Premises;

         7.2.4.   the Tenant and the Tenant's employees, other agents and Guests
                  shall not create, permit or continue any Nuisance in or around
                  the Carnegie Center Complex,  the Leased  Premises,  the Other
                  Leased Premises,  the Building,  the Common Facilities and the
                  Property;

                                       -4-

<PAGE>



         7.2.5.   The Tenant and the Tenant's employees, other agents and Guests
                  shall not permit the Leased Premises to be regularly  occupied
                  by more  than one  individual  per 200  square  feet of usable
                  floor space of the Leased Premises;

         7.2.6.   the Tenant and the Tenant's employees, other agents and Guests
                  shall  comply  with all  Federal,  state and  local  statutes,
                  ordinances,  rules,  regulations and orders as they pertain to
                  the Tenant's use and occupancy of the Leased Premises,  to the
                  conduct of the Tenant's  business and to the use of the Common
                  Facilities,  except that this subsection shall not require the
                  Tenant to make any  structural  changes  that may be  required
                  thereby  that are  generally  applicable  to the Building as a
                  whole;

         7.2.7.   the Tenant and the Tenant's employees, other agents and Guests
                  shall  comply  with  the  requirements  of the  Board  of Fire
                  Underwriters (or successor  organization) and of any insurance
                  carriers  providing  liability,  property,  casualty or excess
                  insurance coverage regarding the Property,  the Building,  the
                  Common   Facilities  or  any  portions   thereof,   any  other
                  improvements  on the Property and the Carnegie Center Complex,
                  except  that this  subsection  shall not require the Tenant to
                  make any structural  changes that may be required thereby that
                  are generally applicable to the Building as a whole;

          7.2.8.    the  Tenant and the  Tenant's  employees,  other  agents and
                    Guests shall not bring or  discharge  any  substance  (solid
                    liquid or gaseous),  or conduct any  activity,  in or on the
                    Carnegie Center  Complex,  the Property,  the Building,  the
                    Common  Facilities  or the Leased  Premises  that shall have
                    been  identified  by  the  scientific  community  or by  any
                    Federal, state or local statute (including, without limiting
                    the generality of the foregoing,  the Spill Compensation and
                    Control  Act  (58  N.J.S.A.   sec.23.11  et  seq.)  and  the
                    Industrial  Site  Recovery  Act (13  N.J.S.A.  sec.1  K-6 et
                    seq.), as they may be amended),  ordinance, rule, regulation
                    or  order  as  toxic  or  hazardous  to  health  or  to  the
                    environment;

        7.2.9.      the Tenant and  the  Tenant's  employees,  other  agents and
                    Guests shall not draw  electricity in the Leased Premises in
                    excess of the rated  capacity of the  electrical  conductors
                    and  safety   devices   including,   without   limiting  the
                    generality of the foregoing,  circuit breakers and fuses, by
                    which  electricity  is  distributed  to and  throughout  the
                    Leased  Premises and,  without the prior written  consent of
                    the  Landlord  in  each  instance,  shall  not  connect  any
                    fixtures,   appliances   or  equipment  to  the   electrical
                    distribution  system  serving  the  Building  and the Leased
                    Premises other than typical  professional  office  equipment
                    such as minicomputers, microcomputers, typewriters, copiers,
                    telephone  systems,  coffee machines and table top microwave
                    ovens,  none of which,  considered  individually  and in the
                    aggregate,   overall  and  per  fused  or  circuit   breaker
                    protected circuit, shall exceed the above limits;

       7.2.10.      on  a  timely  basis  the  Tenant  shall  pay  directly  and
                    promptly  to the  respective  taxing  authorities  any taxes
                    (other than Taxes) charged,  assessed or levied  exclusively
                    on the  Leased  Premises  or  arising  exclusively  from the
                    Tenant's use and occupancy of the Leased Premises; and

       7.2.11.      the Tenant  shall not  initiate any  appeal  or  contest  of
                    any  assessment  or  collection  of  Taxes  for  any  period
                    without, in each instance,  the prior written consent of the
                    Landlord

                                       -5-

<PAGE>



                which,  without  being  deemed  unreasonable,  the  Landlord may
                withhold if the Building was not 90% occupied by paying  tenants
                throughout that period or if the Tenant is not joined by tenants
                of Other Leased Premises that leased throughout that period, and
                that  are  then  leasing,  at  least  80%  of all  Other  Leased
                Premises, determined by their gross rentable floor space.

7.3.     Tenant agrees to prepare, furnish and enforce a traffic management plan
         (the "Traffic  Plan") that the Landlord can submit in  connection  with
         site plan approval or other governmental requirements. The Traffic Plan
         shall  include,  but not be limited to, such matters as staggered  work
         schedules and van pooling.  Landlord  agrees that the Regular  Business
         Hours  shall be  extended,  if  necessary,  to take  into  account  any
         staggered work schedule required under the Traffic Plan.

8.       Utilities, Services, Maintenance and Repairs.

8.1.     The Landlord shall provide or arrange for the provision of:

         8.1.1.   such maintenance and repair of the Building (except the Leased
                  Premises and Other Leased  Premises);  the Common  Facilities;
                  and the heating, ventilation and air conditioning systems, any
                  plumbing  systems and the electrical  systems in the Building,
                  the Common  Facilities,  the Leased  Premises and Other Leased
                  Premises as is  customarily  provided  for first class  office
                  buildings in the immediate area;

         8.1.2.   such  garbage   removal  from  the  Building  and  the  Common
                  Facilities and such janitorial services for the Building,  the
                  Leased  Premises and Other Leased  Premises as is  customarily
                  provided  for first class office  buildings  in the  immediate
                  area;

         8.1.3.   water  to the Building  and, if the  appropriate  plumbing has
                  been installed  therein, the Leased  Premises and Other Leased
                  Premises;

         8.1.4.   sewage disposal for the Building;

         8.1.5.   passenger elevator service for the Building;

         8.1.6.   snow  clearance from, and sweeping of, Parking  Facilities and
                  driveways which are part of the Property; and

         8.1.7.   the maintenance of landscaping which is part of the Property.

8.2.     The Landlord shall provide or arrange for the provision of:

         8.2.1.   such maintenance and repair of the Leased Premises, except for
                  refinishing walls and wall treatments,  base, ceilings,  floor
                  treatments  and  doors  in  general  from  time to time or for
                  gouges,  spots,  marks,  damage or defacement caused by anyone
                  other than the Landlord,  its employees and other agents,  and
                  except for the Tenant's furniture, furnishings,  equipment and
                  other property;

         8.2.2.   such  maintenance  and  repair of the Other  Leased  Premises,
                  except  for  refinishing  walls  and  wall  treatments,  base,
                  ceilings,  floor  treatments and doors in general from time to
                  time or for gouges,  spots, marks, damage or defacement caused
                  by anyone other than the

                                       -6-

<PAGE>



                  Landlord,  its employees and other agents,  and except for the
                  respective  tenants'  furniture,  furnishings,  equipment  and
                  other property;

         8.2.3.   the  electricity  required for the  operation of the Building,
                  the Property and the Common Facilities during Regular Business
                  Hours  and,  on a reduced  service  basis,  during  other than
                  Regular  Business  Hours,  and, at all times,  the electricity
                  required for the Leased Premises and Other Leased Premises;

         8.2.4.   such heat,  ventilation and air conditioning for the Building,
                  the  Leased   Premises  and  Other   Leased   Premises  as  is
                  customarily  provided for first class office  buildings in the
                  immediate area for the  comfortable use of the Building during
                  Regular Business Hours; and

         8.2.5.   heated water to the Building  (except the Leased  Premises and
                  Other  Leased  Premises,   unless  the  appropriate  plumbing,
                  fixtures  and hot water  heating  units  have  been  installed
                  therein).

8.3.     Except as  specifically  set forth in subsections 8.1 and 8.2.1 of this
         Agreement, the Tenant shall maintain and repair the Leased Premises and
         keep the Leased  Premises in as good  condition and repair,  reasonable
         wear and use excepted,  as the Leased  Premises are upon the completion
         of any improvements contemplated by section 5 of this Agreement.

9. Allocation of the Expense of Utilities,  Services,  Maintenance,  Repairs and
Taxes.

9.1.     All Tenant Electric Charges shall be borne by the Tenant.

9.2.     Between  the  Commencement  Date  and the  end of the No  Pass  Through
         Period,  the  Tenant's  Share of all  Operational  Expenses  and  Taxes
         incurred during such period shall be borne by the Landlord.

9.3.     Between the day after the end of the No Pass Through Period and the end
         of the Term,  the  Tenant's  Share of  Operational  Expenses  and Taxes
         incurred during each annual or shorter period ending on (a) December 31
         of each year and (b) the end of the Term shall be borne as follows:

         9.3.1.   the Tenant's Share of: Operational Expenses and Taxes incurred
                  during each such period of 12 months (or shorter  period),  up
                  to the amounts of Base Year Operational Expenses and Base Year
                  Taxes,   respectively  (or  proportional  amount  thereof  for
                  periods  shorter  than  12  months),  shall  be  borne  by the
                  Landlord; and

         9.3.2.   the  Tenant's  Share  of:  the  amounts  by which  Operational
                  Expenses  and Taxes  incurred  during  each such  period of 12
                  months  (or  shorter  period)  exceed  Base  Year  Operational
                  Expenses and Base Year Taxes,  respectively  (or  proportional
                  amount  thereof for periods  shorter than 12 months)  shall be
                  allocated  to, and borne by,  the Tenant as more  specifically
                  set forth in section 10 of this Agreement.

                                       -7-

<PAGE>



10.      Computation and Payment of Allocated  Expenses of Utilities,  Services,
         Maintenance, Repairs, Taxes and Capital Expenditures.

10.1.    The Tenant shall promptly pay the following  additional  amounts to the
         Landlord at the respective times set forth below:

         10.1.1. commencing with  the  first  day  after  the end of the No Pass
                Through  Period,  and on the first day of each month  thereafter
                during the Term, one-twelfth of the Tenant's Share of the amount
                by which Taxes for the then current  calendar  year exceeds Base
                Year Taxes,  computed in accordance with subsection 10.5 of this
                Agreement.  When Landlord  knows of facts which cause a revision
                of the  estimate,  it may serve a revised  estimate and, for the
                balance of the current  calendar  year,  the estimated  payments
                shall be made accordingly;

         10.1.2. within 20  days  of  the Landlord's giving notice to the Tenant
                after the close of each calendar  year closing  during the Term,
                commencing  with the first calendar year closing after the close
                of the No Pass  Through  Period,  and after the end of the Term,
                the  Tenant's  Share of the  difference  between the  Landlord's
                previously  projected  amount of Taxes for such  period  and the
                actual amount of Taxes for such period, in either case in excess
                of Base Year Taxes,  computed in accordance with subsection 10.6
                of this Agreement  (unless such difference is a negative amount,
                in which case the Landlord shall credit such difference  against
                any amounts  next due from the Tenant under  subsections  10.1.1
                and 10.5 of this Agreement);

         10.1.3. commencing  with  the  first  day  after the end of the No Pass
                Through  Period,  and on the first day of each month  thereafter
                during the Term, one-twelfth of the Tenant's Share of the amount
                by which Operational Expenses for the then current calendar year
                exceed Base Year  Operational  Expenses,  computed in accordance
                with subsection  10.7 of this Agreement.  When Landlord knows of
                facts  which cause a revision  of the  estimate,  it may serve a
                revised  estimate  and, for the balance of the current  calendar
                year, the estimated payments shall be made accordingly;

         10.1.4. within 20  days  of  the Landlord's giving notice to the Tenant
                after the close of each calendar  year closing  during the Term,
                commencing  with the first calendar year closing after the close
                of the No Pass  Through  Period,  and after the end of the Term,
                the  Tenant's  Share of the  difference  between the  Landlord's
                previously  projected  amount of  Operational  Expenses for such
                period and the actual  amount of  Operational  Expenses for such
                period,  in  either  case in  excess  of Base  Year  Operational
                Expenses,  computed in accordance  with  subsection 10.8 of this
                Agreement (unless such difference is a negative amount, in which
                case the  Landlord  shall  credit  such  difference  against any
                amounts  next due from the Tenant under  subsections  10.1.5 and
                10.7 of this Agreement);

         10.1.5. commencing  with  the  first  day  of the first month after the
                Landlord  gives any notice  contemplated  by subsection  10.9 of
                this  Agreement to the Tenant and continuing on the first day of
                each month  thereafter  until the  earlier of (a) the end of the
                Term or (b) the last month of the  useful  life set forth in the
                respective notice, one-twelfth of the

                                       -8-

<PAGE>



                Tenant's  Share of any  Annual  Amortized  Capital  Expenditure,
                computed in accordance with subsection 10.9 of this Agreement;

         10.1.6. on the first day of each month  during  the  Term,  the monthly
                Tenant Electric Charges,  computed in accordance with subsection
                10.10 of this Agreement; and

         10.1.7. promptly  as  and  when  billed  therefor by the Landlord,  the
                amount of any  expense  which  would  otherwise  fall within the
                definition of Operational  Expenses,  but which is  specifically
                paid or incurred by the Landlord for operation  and  maintenance
                of the Building,  the Common  Facilities or the Property outside
                Regular  Business Hours at the specific request of the Tenant or
                the amount of any expenditure incurred for maintenance or repair
                of damage to the Building, the Common Facilities,  the Property,
                the Leased Premises or the Other Leased Premises caused directly
                or  indirectly,  in whole or in part,  by the  active or passive
                negligence  or  intentional  act  of  the  Tenant  or any of its
                employees, other agents or Guests.

10.2.    "Operational  Expenses"  means all  expenses  paid or  incurred  by the
         Landlord in  connection  with the Property,  the  Building,  the Common
         Facilities  and  any  other  improvements  on the  Property  and  their
         operation  and  maintenance  (other  than Taxes  (which are  separately
         allocated  to the  Tenant in  accordance  with  subsections  10.1.1 and
         10.1.2 of this Agreement),  Capital  Expenditures (which are separately
         allocated to the Tenant in accordance  with  subsection  10.1.5 of this
         Agreement) and those expenses  contemplated  by subsections  10.1.6 and
         10.1.7 of this Agreement))  including,  without limiting the generality
         of the foregoing:

         10.2.1.    Utilities Expenses;

         10.2.2.    the  expense of  providing  the  services,  maintenance  and
                    repairs  contemplated by subsections 8.1, 8.2.1 and 8.2.2 of
                    this  Agreement,   whether  furnished  by  the  Land  lord's
                    employees or by independent contractors or other agents;

         10.2.3.    wages,   salaries,   fees  and   other    compensation   and
                    payments and payroll taxes and  contributions  to any social
                    security,   unemployment  insurance,   welfare,  pension  or
                    similar fund and payments for other fringe benefits required
                    by law or union agree ment (or, if the  employees  or any of
                    them are not  represented  by a  union,  then  payments  for
                    benefits  comparable  to those  generally  required by union
                    agreement in first class office  buildings in the  immediate
                    area  which  are  unionized)  made  to or on  behalf  of any
                    employees  of  Landlord   performing  services  rendered  in
                    connection   with  the  operation  and  maintenance  of  the
                    Building, the Common Facilities and the Property, including,
                    without  limiting the generality of the foregoing,  elevator
                    opera tors,  elevator  starters,  window cleaners,  porters,
                    janitors, maids,  miscellaneous handymen,  watchmen, persons
                    engaged in  patrolling  and  protecting  the  Building,  the
                    Common Facilities and the Property,  carpenters,  engineers,
                    firemen, mechanics, electricians, plumbers, other tradesmen,
                    other persons  engaged in the operation and  maintenance  of
                    the  Building,  Common  Facilities  and  Property,  Building
                    superinten  dent  and  assistants,   Building  manager,  and
                    clerical and administrative personnel;

         10.2.4.    the uniforms of all employees and the cleaning, pressing and
                    repair thereof;

                                       -9-

<PAGE>



         10.2.5.    premiums  and  other   charges   incurred  by Landlord  with
                    respect  to all  insurance  relating  to the  Building,  the
                    Common  Facilities  and the Property and the  operation  and
                    maintenance thereof, including, without limitation: property
                    and  casualty,   fire  and  extended   coverage   insurance,
                    including windstorm, flood, hail, explosion, other casualty,
                    riot, rioting attending a strike, civil commotion, aircraft,
                    vehicle and smoke  insurance;  public  liability  insurance;
                    elevator,  boiler and machinery insurance;  excess liability
                    coverage insurance;  use and occupancy  insurance;  workers'
                    compensation and health, accident, disability and group life
                    insurance for all  employees;  and casualty rent  insurance;

         10.2.6.    sales  and  excise  taxes and the like upon any  Operational
                    Expenses and Capital Expenditures;

         10.2.7.    management  fees  of  any  independent   managing  agent for
                    the Property, the Building or the Common Facilities;  and if
                    there  shall be no  independent  managing  agent,  or if the
                    managing  agent  shall  be  a  person  affiliated  with  the
                    Landlord,  the  management  fees that would  customarily  be
                    charged for the management of the Property, the Building and
                    the  Common  Facilities  by  an  independent,   first  class
                    managing agent in the immediate area;

         10.2.8.    the   cost   of   replacements   for   tools,  supplies  and
                    equipment  used  in  the  operation,  service,  maintenance,
                    improvement,   inspection,  repair  and  alteration  of  the
                    Building, the Common Facilities and the Property;

         10.2.9.    the  cost  of  repainting  or  otherwise   redecorating  any
                    part of the Building or the Common Facilities;

         10.2.10.   decorations  for  the  lobbies  and  other Common Facilities
                    in the Building;

         10.2.11.    the  cost  of   licenses,   permits  and  similar  fees and
                    charges related to operation,  repair and maintenance of the
                    Building, the Property and the Common Facilities;

         10.2.12.   an  allocable   share  of  service,   replacement,   repair,
                    maintenance and other charges  assessed from time to time by
                    the Carnegie Center Owner's  Association II to the Building;
                    and

         10.2.13.   any  and  all  other   expenditures  of  the   Landlord   in
                    connection  with  the  operation,   alteration,   repair  or
                    maintenance  of the Property,  the Common  Facilities or the
                    Building as a first-class  office building and facilities in
                    the immediate area which are properly  treated as an expense
                    fully  deductible as incurred in accordance  with  generally
                    applied real estate accounting practice.

10.3.   "Capital  Expenditures" means the  following   expenditures  incurred or
        paid by the Landlord in connection with the Property,  the Building, the
        Common  Facilities and any other  improvements on the Property:  

         10.3.1.    all  costs  and  expenses   incurred   by  the  Landlord  in
                    connection  with  retro-fitting  the entire  Building or the
                    Common  Facilities,  or any portion thereof,  to comply with
                    any  change  in  Federal,  state  or  local  statute,  rule,
                    regulation,  order or requirement  which change takes effect
                    after the original completion of the Building;

                                      -10-

<PAGE>



         10.3.2.    all costs and  expenses  incurred by the Landlord to replace
                    and  improve  the  Property,  the  Building  or  the  Common
                    Facilities or portions thereof for the purpose of contin ued
                    operation  of the  Property,  the  Building  and the  Common
                    Facilities as a first class office  complex in the immediate
                    area; and

         10.3.3.    all  costs  and   expenses   incurred  by  the  Landlord  in
                    connection  with the  installation  of any energy,  labor or
                    other cost saving device or system on the Property or in the
                    Building or the Common Facilities.

10.4.   Neither  "Operational  Expenses"   nor  "Capital   Expenditures"   shall
        include any of the following:

         10.4.1.    principal or interest on  any  mortgage  indebtedness on the
                    Property, the Building or any portion thereof;

         10.4.2.    any capital expenditure, or amortized portion thereof, other
                    than   those   included   in  the   definition   of  Capital
                    Expenditures set forth in subsection 10.3 above;

         10.4.3.    expenditures for any leasehold  improvement which is made in
                    connection  with  the  preparation  of  any  portion  of the
                    Building for  occupancy by a new tenant or which is not made
                    generally  to or for the benefit of the Leased  Premises and
                    all Other  Leased  Premises or  generally to the Building or
                    the Common Facilities;

         10.4.4.    to the extent the  Landlord  actually  receives  proceeds of
                    property and casualty  insur ance  policies on the Building,
                    other improvements on the Property or the Common Facilities,
                    expenditures for repairs or replacements  occasioned by fire
                    or other casualty to the Building or the Common Facilities;

         10.4.5.    expenditures   for  repairs,   replacements  or   rebuilding
                    occasioned  by  any of the events contemplated by section 16
                    of this Agreement;

         10.4.6.    expenditures  for costs,  including  advertising and leasing
                    commissions,  incurred in  connection  with efforts to lease
                    portions of the  Building and to procure new tenants for the
                    Building;

         10.4.7.    expenditures for the  salaries and benefits of the executive
                    officers, if any, of the Landlord; and

         10.4.8.    depreciation  (as that term is used in the accounting  sense
                    in the context of generally  applied real estate  accounting
                    practice) of the  Building,  the Common  Facilities  and any
                    other improvement on the Property.

10.5.    As soon as  practicable  after the close of the No Pass Through  Period
         and December 31 of each year thereafter, any portion of which is during
         the Term,  the Landlord  shall furnish the Tenant with a notice setting
         forth:  

         10.5.1.    Taxes   billed,  or  if  a  bill has not then been  received
                    for the entire period,  the Land lord's  projection of Taxes
                    to be billed, for the then current calendar year;

         10.5.2.    the amount of Base Year Taxes;

         10.5.3.    the amount, if  any, by which item 10.5.1 above exceeds item
                    10.5.2 above; and

         10.5.4.    the Tenant's Share of item 10.5.3 above.

                                      -11-

<PAGE>



10.6.    As soon as  practicable  after December 31 of each year during the Term
         and after the end of the Term,  the Landlord  shall  furnish the Tenant
         with a notice setting forth:

         10.6.1.    the  actual  amount  of  Taxes for  the  preceding  calendar
                    year in excess of Base Year  Taxes (or  proportional  amount
                    thereof for shorter periods during the Term);

         10.6.2.    the  Landlord's  previously  projected  amount  of Taxes for
                    the preceding calendar year in excess of Base Year Taxes (or
                    proportional  amount thereof for shorter  periods during the
                    Term);

         10.6.3.    the difference obtained  by  subtracting  item  10.6.2 above
                    from item 10.6.1 above; and

         10.6.4.    the Tenant's Share of item 10.6.3 above.

10.7.    As soon as  practicable  after the close of the No Pass Through  Period
         and December 31 of each year thereafter, any portion of which is during
         the Term,  the Landlord  shall furnish the Tenant with a notice setting
         forth: 

         10.7.1.    the Landlord's  projection  of  annual  Operational Expenses
                    for the current period (if any portion thereof is during the
                    Term);

         10.7.2.    the amount of the Base Year Operational Expenses;

         10.7.3.    the amount, if any, by which item 10.7.1 above exceeds  item
                    10.7.2 above; and

         10.7.4.    the Tenant's Share of item 10.7.3 above.

10.8.    As soon as  practicable  after December 31 of each year during the Term
         and after the end of the Term,  the Landlord  shall  furnish the Tenant
         with a notice setting forth:

         10.8.1.    the  actual  amount   of   Operational   Expenses   for  the
                    preceding  calendar year in excess of Base Year  Operational
                    Expenses (or proportional amount thereof for shorter periods
                    during the Term);

         10.8.2.    the Landlord's  previously  projected  amount of Operational
                    Expenses for the preced ing calendar  year in excess of Base
                    Year Operational  Expenses (or  proportional  amount thereof
                    for shorter periods during the Term);

         10.8.3.    the difference obtained by  subtracting  item  10.8.2  above
                    from item 10.8.1 above; and

         10.8.4.    the Tenant's Share of item 10.8.3 above.

10.9.    As soon as practicable  after  incurring any Capital  Expenditure,  the
         Landlord shall furnish the Tenant with a notice setting forth:

         10.9.1.    a  description  of  the  Capital Expenditure and the subject
                    thereof;

         10.9.2.    the  date  the   subject   of   the    respective    Capital
                    Expenditure  was first placed into service and the period of
                    useful life selected by the Landlord in connection  with the
                    determi nation of the Annual Amortized Capital Expenditure;

         10.9.3.    the amount of the Annual Amortized Capital Expenditure; and

         10.9.4.    the Tenant's Share of item 10.9.3 above.

                                      -12-

<PAGE>



10.10.  As  soon  as  practicable  after the Commencement  Date and from time to
        time  thereafter,  the Landlord  shall  furnish the Tenant with a notice
        setting forth its estimate of Tenant Electric Charges per month.  Unless
        the Tenant desires to question the Landlord's  then most recent estimate
        of Tenant  Electric  Charges  exclusively in the manner set forth below,
        the  Landlord's  then most  recent  estimate  shall be binding and shall
        continue in effect until any question  raised by the Tenant is otherwise
        resolved in accordance with this subsection  10.10 of the Agreement.  If
        the  Tenant  desires  to  question  the  Landlord's  estimate  of Tenant
        Electric  Charges,  the Tenant  shall give notice to the Landlord of its
        desire.  Upon receipt of the Tenant's notice, the Landlord shall obtain,
        at the Tenant's expense, a reputable,  independent electrical engineer's
        formal written estimate and computation of the Tenant Electric  Charges.
        The engineer's estimate and computation of Tenant Electric Charges shall
        thereupon  control for a 12 month period com mencing with the date as of
        which it is given effect as to Tenant  Electric  Charges,  and until the
        Landlord furnishes the Tenant with a subsequent notice setting forth its
        estimate of Tenant Electric Charges per month, except to the extent that
        the Landlord may increase  them in  proportion to increases in Utilities
        Expenses during the same period.

10.11.  Within  30  days  after  the  Landlord  gives any notice  enumerated  in
        subsections  10.5  through  10.10 of this  Agreement,  the Tenant or the
        Tenant's authorized agent, upon one week's prior notice to the Landlord,
        may inspect the  Landlord's  books and  records,  as they pertain to the
        particular  expense in question,  at the Landlord's office regarding the
        subject of any such notice to verify the  amount(s)  and  calculation(s)
        thereof.  After  payment of the Tenant's  Share in  accordance  with the
        provisions  of section 10 of this  Agreement,  no further audit shall be
        conducted  except with  respect to items which may have been  questioned
        within the 30 day period.  Tenant agrees that no audit will be conducted
        by an auditor  engaged,  in whole or in part, on a contingent fee basis.
        If an audit is  conducted,  the Landlord  shall have the right to verify
        that the provisions of this prohibition have been satisfied.

10.12.  The  mere  enumeration  of an item within the definitions of Operational
        Expenses and Capital  Expenditures in subsections  10.2 and 10.3 of this
        Agreement,  respectively, shall not be deemed to create an obligation on
        the part of the  Landlord to provide  such item  unless the  Landlord is
        affirmatively required to provide such item elsewhere in this Agreement.

11.      Leasehold Improvements, Fixtures and Trade Fixtures.

All leasehold  improvements to the Leased  Premises,  fixtures  installed in the
Leased  Premises and the blinds and floor  treatments or coverings  shall be the
property of the Landlord, regardless of when, by which party or at which party's
cost the item is installed. Movable furniture,  furnishings,  trade fixtures and
equipment of the Tenant which are in the Leased  Premises  shall be the property
of the  Tenant,  except  as may  otherwise  be set forth in  section  23 of this
Agreement. 

12. Alterations,  Improvements and Other Modifications by the Tenant.

12.1.   The  Tenant  shall  not  make  any  alterations,  improvements  or other
        modifications to the Leased Premises which effect structural  changes in
        the Building or any portion  thereof,  change the functional  utility or
        rental value of the Leased Premises or, except as may be contemplated by
        section 5 of this Agreement prior to the Commencement  Date,  affect the
        mechanical,  electrical,  plumbing  or other  systems  installed  in the
        Building or the Leased Premises.

                                      -13-

<PAGE>



12.2.    The  Tenant  shall  not make any  other  alterations,  improvements  or
         modifications to the Leased  Premises,  the Building or the Property or
         make any boring in the ceiling,  walls or floor of the Leased  Premises
         or the Building unless the Tenant shall have first:

         12.2.1.    furnished   to   the   Landlord    detailed,    New   Jersey
                    architect-certified   construction  drawings,   construction
                    specifications  and,  if  they  pertain  in  any  way to the
                    heating,  ventilation and air  conditioning or other systems
                    of  the  Building,   related  engineering  design  work  and
                    specifications    regarding,   the   proposed   alterations,
                    improvements or other modifications;

         12.2.2.    not received a notice from the Landlord objecting thereto in
                    any respect within 30 days of the furnishing  thereof (which
                    shall not be deemed the Landlord's  affirmative  consent for
                    any purpose);

         12.2.3.    obtained any necessary or  appropriate  building  permits or
                    other approvals from the  Municipality  and, if such permits
                    or other approvals are conditional, satisfied all conditions
                    to the satisfaction of the Municipality; and

         12.2.4.    met,  and  continued  to  meet, all the following conditions
                    with  regard to any  contractors  selected by the Tenant and
                    any subcontractors,  including materialmen, in turn selected
                    by any of them:

                    12.2.4.1.       the Tenant  shall  have  sole responsibility
                                    for  payment  of,  and   shall   pay,   such
                                    contractors;

                    12.2.4.2.       the Tenant  shall  have sole  responsibility
                                    for coordinating,  and shall coordinate, the
                                    work to be  supplied  or  performed  by such
                                    contractors,  both among themselves and with
                                    any contractors selected by the Landlord;


                    12.2.4.3.       the  Tenant  shall not permit or suffer  the
                                    filing  of  any   mechanic's     notice   of
                                    intention  or  other  lien  or   prospective
                                    lien by any such contractor or subcontractor
                                    with respect to the  Property,  the   Common
                                    Facilities,  the  Building   or   any  other
                                    improvements on the Property;  and if any of
                                    the foregoing  should be filed by  any  such
                                    contractor or subcontractor,the Tenant shall
                                    forthwith  obtain  and  file   the  complete
                                    discharge  and  release  thereof  or provide
                                    such  payment   bond(s)  from  a  reputable,
                                    financially sound  institutional  surety  as
                                    will,  in  the  opinions  of  the  Landlord,
                                    the holders of any mortgage indebtedness on,
                                    or  other  interest  in,  the  Property, the
                                    Building, the Common Facilities or any other
                                    improvements   on  the  Property,   or   any
                                    portions thereof, and their respective title
                                    insurers,  be    adequate   to   assure  the
                                    complete  discharge  and  release thereof;

                    12.2.4.4.       prior to any such contractor's entering upon
                                    the  Property,  the  Building  or the Leased
                                    Premises or commencing work the Tenant shall
                                    have deliv ered to the  Landlord (a) all the
                                    Tenant's certificates of insurance set forth
                                    in section 14 of this Agreement,  conforming
                                    in all  respects  to the  require  ments  of
                                    section 14 of this  Agreement,  except  that
                                    the  effective  dates of all such  insurance
                                    policies   shall   be   prior  to  any  such
                                    contractor's entering

                                      -14-

<PAGE>



                                    upon  the  Property,  the  Building  or  the
                                    Leased  Premises or commencing  work (if any
                                    work  is   scheduled  to  begin  before  the
                                    Commencement    Date)   and   (b)    similar
                                    certificates  of insurance  from each of the
                                    Tenant's con tractors providing for coverage
                                    in equivalent  amounts,  together with their
                                    respective    certificates    of    workers'
                                    compensation insurance, employer's liability
                                    insurance and products-completed  operations
                                    insurance,  the latter providing coverage in
                                    at  least  the  amount   required   for  the
                                    Tenant's    comprehensive   general   public
                                    liability and excess insurance;

                    12.2.4.5.       each  such  contractor  shall  be a party to
                                    collective  bargaining agreements with those
                                    unions that are certified as the  collective
                                    bargaining agents of all bargaining units of
                                    such   contractor,   of   which   all   such
                                    contractor's workpersons shall be members in
                                    good standing;

                    12.2.4.6.       each such contractor shall perform its  work
                                    in  a  good  and  workpersonlike  manner and
                                    shall  not  interfere  with  or  hinder  the
                                    Landlord  or  any  other   contractor in any
                                    manner;

                    12.2.4.7.       there  shall  be no  labor  dispute  of  any
                                    nature   whatsoever   involving   any   such
                                    contractor  or  any   workpersons   of  such
                                    contractor  or the  unions of which they are
                                    members  with  anyone;  and if  such a labor
                                    dispute  exists or comes into  existence the
                                    Tenant shall forthwith, at the Tenant's sole
                                    cost   and   expense,    remove   all   such
                                    contractors and their  workpersons  from the
                                    Building,  the  Common  Facilities  and  the
                                    Property; and

                    12.2.4.8.       the    Tenant    shall    have    the   sole
                                    responsibility   for  the  security  of  the
                                    Leased   Premises   and   all   contractors'
                                    materials, equipment and work, regardless of
                                    whether   their  work  is  in   progress  or
                                    completed.

12.3.    After  the  Commencement  Date,  the  Tenant  shall  not apply any wall
         covering  (except  latex  based flat paint) or other  treatment  to the
         walls of the Leased  Premises  without the prior written consent of the
         Landlord.

13. Landlord's Rights of Entry and Access.

The Landlord and its authorized  agents shall have the following rights of entry
and access to the Leased Premises:

13.1.   In  case of  any emergency or threatened emergency,  at any time for any
        purpose which the Landlord  reasonably believes under such circumstances
        will serve to prevent,  eliminate or reduce the emergency, or the threat
        thereof, or damage or threatened damage to persons and property.

13.2    Upon at least one day's prior verbal  advice to the Tenant,  at any time
        for the purpose of erecting or constructing improvements, modifications,
        alterations  and other  changes to the Building or any portion  thereof,
        including,  without limiting the generality of the foregoing, the Leased
        Premises,  the Common  Facilities  or the Property or for the purpose of
        repairing,  maintaining or cleaning them, whether for the benefit of the
        Landlord,  the  Building,  all tenants of Other  Leased  Premises in the
        Building, or one or more tenants of Other Leased Premises,  the Carnegie
        Center  Complex or others.  In  connection  with any such  improvements,
        modifications, alterations, other

                                      -15-

<PAGE>



         changes,  repairs,  maintenance or cleaning, the Landlord may close off
         such portions of the Property,  the Building and the Common  Facilities
         and  interrupt  such  services as may be necessary to  accomplish  such
         work, without liability to the Tenant therefor and without such closing
         or interruption  being deemed an eviction or  constructive  eviction or
         requiring an  abatement of Rent.  However,  in  accomplishing  any such
         work, the Landlord shall endeavor not to materially  interfere with the
         Tenant's use and enjoyment of the Leased Premises or the conduct of the
         Tenant's  business  and to  minimize  interference,  inconvenience  and
         annoyance to the Tenant.

13.3.    At all  reasonable  hours for the purpose of  operating,  inspecting or
         examining the Building, including the Leased Premises, or the Property.

13.4.    At any time after the Tenant has vacated the Leased  Premises,  for the
         purpose  of  preparing  the  Leased  Premises  for  another  tenant  or
         prospective tenant.

13.5.    If practicable by appointment with the Tenant,  at all reasonable hours
         for the purpose of showing  the  Building  to  prospective  purchasers,
         mortgagees and prospective  mortgagees and  prospective  ground lessees
         and lessors.

13.6.    If practicable by appointment with the Tenant,  at all reasonable hours
         during the last six months of the Term for the  purpose of showing  the
         Leased Premises to prospective tenants thereof.

13.7.    The mere  enumeration of any right of the Landlord  within this section
         13 of the Agreement  shall not be deemed to create an obligation on the
         part of the  Landlord to exercise any such right unless the Landlord is
         affirmatively  required  to  exercise  such  right  elsewhere  in  this
         Agreement.

14.      Liabilities and Insurance Obligations.

14.1.   The  Tenant  shall,  at  the Tenant's own expense,  purchase  before the
        Commencement  Date, and maintain in full force and effect throughout the
        Term and any other period during which the Tenant may have possession of
        the Leased  Premises,  the  following  types of insurance  coverage from
        financially sound and reputable  insurers,  licensed by the State of New
        Jersey to provide such insurance and acceptable to the Landlord,  in the
        minimum amounts set forth below, each of which insurance  policies shall
        be for the  benefit  of, and shall  name the  Landlord,  the  Landlord's
        managing agent and mortgagees and ground lessors known to the Tenant, if
        any,  of the  Building,  the  Common  Facilities,  the  Property  or any
        interest  therein,  their  successors and assigns as additional  persons
        insured,   and  none  of  which  insurance   policies  shall  contain  a
        "co-insurance" clause:

        14.1.1. commercial  general  liability   insurance   (including   "broad
                form  and   contractual   liabil  ity"   coverage)   and  excess
                ("umbrella")  insurance which,  without limiting the general ity
                of the foregoing,  considered together shall insure against such
                risks as  bodily  injury,  death  and  property  damage,  with a
                combined  single limit of not less than  $3,000,000.00  for each
                occurrence; and

        14.1.2. "all-risks"  property  insurance  covering  the  Leased Premises
                in an amount sufficient, as determined by the Landlord from time
                to  time,  to  cover  the  replacement  costs  for all  Tenant's
                alterations,   improvements,   fixtures  and  personal  property
                located in or on the Leased Premises.

                                      -16-

<PAGE>



14.2.    With respect to risks:

        14.2.1. as to  which  this  Agreement  requires either party to maintain
                insurance, or

        14.2.2. as  to  which  either  party  is  effectively  insured  and  for
                which risks the other party may be liable, the party required to
                maintain such insurance and the party effectively  insured shall
                use its best efforts to obtain a clause,  if available  from the
                respective  insurer,  in each such  insurance  policy  expressly
                waiving any right of recovery,  by reason of subrogation to such
                party's  rights  or  otherwise,  the  respective  insurer  might
                otherwise  have or obtain  against the other  party,  so long as
                such a clause can be obtained in the respective insurance policy
                without  additional  premium  cost.  If  such  a  clause  can be
                obtained  in  the  respective  insurance  policy,  but  only  at
                additional  premium  cost,  such party  shall,  by notice to the
                other  party,  promptly  advise the other party of such fact and
                the amount of the  additional  premium  cost. If the other party
                desires the inclusion of such a clause in the notifying  party's
                respective  insurance policy,  the other party shall,  within 10
                days of  receipt  of the  notifying  party's  notice,  by notice
                advise the notifying  party of its desire and enclose  therewith
                its check in the full  amount of the  additional  premium  cost;
                otherwise the  notifying  party need not obtain such a clause in
                the respective insurance.

14.3.    Each party hereby waives any right of recovery  against the other party
         for any and all damages for property losses and property  damages which
         are actually insured by either party,  but only to the extent:

         14.3.1.    that  the  waiver  set  forth in this  subsection  14.3 does
                    not cause or result in any  cancellation  of, or  diminution
                    in, the insurance  coverage  otherwise  available  under any
                    applicable insurance policy;

         14.3.2.    of the proceeds of any applicable  insurance policy (without
                    adjustment  for any  deductible  amount  set forth  therein)
                    actually received by such party for such respec tive loss or
                    damages; and

         14.3.3.    the substance of the clause  contemplated by subsection 14.2
                    of this Agreement is actually and  effectively  set forth in
                    the  respective  insurance  policy.  The waiver set forth in
                    this  subsection  14.3 of the Agreement shall not apply with
                    respect  to  liability  insurance  policies  (as  opposed to
                    property and casualty insurance policies).

14.4.    The Tenant hereby waives any right of recovery it might  otherwise have
         against  the  Landlord  for  losses  and  damages  caused  actively  or
         passively,  in whole or in part,  by any of the  risks  the  Tenant  is
         required to insure  against in accordance  with  subsections  14.1.1 or
         14.1.2 of this Agreement, unless such waiver would cause or result in a
         cancellation  of,  or  diminution  in,  the  coverage  of the  Tenant's
         policies of insurance against such risks.

14.5.    The Landlord  shall have no liability  whatsoever  to the Tenant or the
         Tenant's  employees,  other  agents or  Guests  or anyone  else for any
         death, bodily injury, property loss or other damages suffered by any of
         them or any of their property which is not caused directly, exclusively
         and entirely by the active gross  negligence or intentional  misconduct
         of the Landlord  without the  intervention or contribution of any other
         cause or contributing factor whatsoever.

                                      -17-

<PAGE>



14.6.    Each  policy  of  insurance  required  under  subsection  14.1  of this
         Agreement shall include  provisions to the effect that:  

         14.6.1.    no  act  or  omission  of the Tenant,  its employees,  other
                    agents  or  Guests  shall  result  in a  loss  of  insurance
                    coverage otherwise available under such policy to any person
                    required to be named as an additional  insured in accordance
                    with subsection 14.1 of this Agreement; and

         14.6.2.    the insurance  coverage afforded by such policy shall not be
                    diminished,  cancelled,  permitted  to expire  or  otherwise
                    terminated for any reason except upon 30 days' prior written
                    notice from the insurer to every person required to be named
                    as an additional  insured in accordance with subsection 14.1
                    of this Agreement.

14.7.   With  respect   to  each  type of  insurance  coverage  referred  to  in
        subsection 14.1 of this Agree ment, prior to the  Commencement  Date the
        Tenant  shall  cause its  insurer(s)  to  deliver  to the  Landlord  the
        certificate(s)  of the insurer(s)  setting forth the name and address of
        the insurer,  the name and address of each additional insured,  the type
        of  coverage  provided,  the  limits  of the  coverage,  any  deductible
        amounts,  the  effective  dates of coverage  and that each policy  under
        which  coverage is provided  affirmatively  includes  provisions  to the
        effect set forth in subsec tion 14.6 of this Agreement. In the event any
        of such certificates indicates a coverage termina tion date earlier than
        the end of the Term or the end of any  other  period  during  which  the
        Tenant may have possession of the Leased Premises, no later than 10 days
        before any such coverage  termination  date, the Tenant shall deliver to
        the  Landlord   respective,   equivalent,   new  certificate(s)  of  the
        insurer(s).

15.      Casualty Damage to Building or Leased Premises.

15.1.   In  the  event of any damage to the  Building or any portion  thereof by
        fire or other  casualty,  with the result that the Leased  Premises  are
        rendered  unusable,  in whole or in part,  then,  unless the Building is
        destroyed or so damaged that the Landlord does not intend to rebuild the
        same,  the  Landlord  shall,  within 30 business  days of the  casualty,
        determine  the period of time  required to restore the  Building and the
        Leased  Premises  (but not  including the  improvements  constructed  or
        installed prior to the Term or during the Term in excess of the original
        allowance for the same).

          15.1.1.   If, in  Landlord's  opinion,   the   restoration   described
                    above will take more than 180 days then  Landlord  may elect
                    to  cancel  this  Agreement  effective  as of  the  date  of
                    casualty.  Notice of the Landlord's election shall be served
                    upon the Tenant within the 30 business day period  described
                    above.

         15.1.2.    If, in Landlord's opinion,  the restoration  described above
                    will take 180 days or less,  then Landlord  shall not cancel
                    this  Agreement and must restore the Building and the Leased
                    Premises  as  aforesaid.  In  either  of  such  events,  the
                    Landlord shall cause  restoration to proceed  diligently and
                    expediently to the extent the Landlord has received proceeds
                    of any  property,  casualty or  liability  insurance  on the
                    damaged  portions (or would have  received such proceeds had
                    it obtained such coverage).

15.2. Rent shall abate from the date of the casualty until:

                                      -18-

<PAGE>



          15.2.1.   such  time  as  the  Leased  Premises are again fully usable
                    and be reduced  during such period by the amount which bears
                    the same  proportion to the Rent  otherwise  payable  during
                    such period as the gross  rentable floor space of the Leased
                    Premises  which  are  rendered  unusable  bears to the gross
                    rentable floor space of the Leased Premises. The restoration
                    of the  improvements  constructed or installed  prior to the
                    Term or during the Term in excess of the original  allowance
                    for the same shall be the  Tenant's  responsibility.  Tenant
                    shall make  reasonable,  good faith efforts to integrate the
                    restoration which is its  responsiblity  with the work which
                    is being  performed by  Landlord.  To the extent that is not
                    feasible, Tenant shall be allowed an additional,  reasonable
                    interval to complete its work,  not to exceed sixty days and
                    Rent shall  abate  during  the  interval  required  for such
                    restoration.  The Landlord  shall  cooperate  with Tenant to
                    integrate the  restoration of such  improvements  during the
                    reconstruction period; or

         15.2.2.    this  Agreement  is canceled  pursuant  to the provisions of
                    subsections 15.1.

15.3.   If, in  the  Landlord's  opinion,  the restoration  described above will
        take more than 180 days and the  Landlord  makes the  election to cancel
        set forth in subsection  15.1 above then  Landlord,  in such event,  may
        proceed with restoration (or  non-restoration) in any manner it chooses,
        without any liability to Tenant.

15.4.    The Tenant shall promptly  advise the Landlord by the quickest means of
         communication  of the occurrence of any casualty damage to the Building
         or the Leased Premises of which the Tenant becomes aware.

16.      Condemnation.

If the Leased Premises,  or any portion  thereof,  or the Building or the Common
Facilities,  or any  substantial  portion  of any of  the  foregoing,  shall  be
acquired  for any public or  quasi-public  use or purpose by  statute,  right of
eminent  domain or private sale in lieu thereof,  with the result the Tenant can
not use and occupy the Leased  Premises for the purpose set forth in  subsection
7.1 of this Agreement,  the Tenant hereby waives any claim against the Landlord,
the condemning  authority or other person acquiring same for any thing of value,
tangible or  intangible,  including,  without  limiting  the  generality  of the
foregoing,  the putative  value of any leasehold  interest or loss of the use of
same,  except for any right the Tenant  might have to make a claim,  independent
of, and without  reference to or having any effect on, any award or claim of the
Landlord,  against the condemning  authority or other  acquiring party regarding
the value of the Tenant's  installed  trade fixtures and other  installed  equip
ment  which are not  removable  from the Leased  Premises  or for  ordinary  and
necessary moving expenses  occasioned  thereby.  
17. Assignment or Subletting by Tenant. 

17.1.     Except as may be  specifically  set  forth in this  section  17 of the
          Agreement, the Tenant shall not:

          17.1.1.   assign,  or  purport  to  assign,  this  Agreement or any of
                    the Tenant's rights hereunder;

          17.1.2.   sublet, or  purport  to  sublet,  the Leased Premises or any
                    portion thereof;

          17.1.3.   license,  or  purport  to  license,  the use or occupancy of
                    the Leased Premises or any portion thereof;

                                      -19-

<PAGE>



         17.1.4.    otherwise  transfer,  or attempt to  transfer  any  interest
                    including, without limiting the generality of the foregoing,
                    a mortgage,  pledge or security interest, in this Agreement,
                    the Leased Premises or the right to the use and occupancy of
                    the Leased Premises; or

         17.1.5.    indirectly    accomplish,    or   permit   or   suffer   the
                    accomplishment  of,  any  of  the  foregoing  by  merger  or
                    consolidation   with  another  entity,   by  acquisition  or
                    disposition  of assets or  liabilities  outside the ordinary
                    course  of  the  Tenant's  business  or  by  acquisition  or
                    disposition,  by the Tenant's  equity owners or subordinated
                    creditors,  of  any of  their  respective  interests  in the
                    Tenant.

17.2.    The  Tenant  shall not assign  this  Agreement  or any of the  Tenant's
         rights  hereunder or sublet the Leased  Premises or any portion thereof
         without  first giving three months' prior notice to the Landlord of its
         desire to assign or sublet and requesting  the  Landlord's  consent and
         without first  receiving the  Landlord's  prior  written  consent.  The
         Tenant's notice to the Landlord shall include:  

         17.2.1.    the  full   name,  address   and  telephone  number  of  the
                    proposed assignee or sublessee;

         17.2.2.    a  description  of  the  type(s)  of  business  in which the
                    proposed  assignee or  sublessee  is engaged and proposes to
                    engage;

         17.2.3.    a description  of  the  precise  use  to  which the proposed
                    assignee  or sublessee intends to put the Leased Premises or
                    portion thereof;

         17.2.4.    the proposed assignee's or subtenant's most recent quarterly
                    and annual financial  statements prepared in accordance with
                    generally  accepted  accounting  principles  and  any  other
                    evidence of financial position and  responsibility  that the
                    Tenant or  proposed  assignee  or  sublessee  may  desire to
                    submit;

         17.2.5.    by diagram  and  measurement  of the actual  square  feet of
                    floor  space,  the  precise  portion of the Leased  Premises
                    proposed to be subject to the  assignment of this  Agreement
                    or to be sublet;

         17.2.6.    a complete,  accurate and detailed  description of the terms
                    of the proposed  assignment or sublease  including,  without
                    limiting the generality of the foregoing, all consider ation
                    paid or given, or proposed to be paid or to be given, by the
                    proposed  assignee,  sublessee or other person to the Tenant
                    and the respective times of payment or delivery; and

         17.2.7.    any other information reasonably requested by the Landlord.

17.3.    By the expiration of the notice period  contemplated by subsection 17.2
         of this Agreement, the Landlord, in its sole discretion, shall take one
         of the following actions by notice to the Tenant: 

         17.3.1.    grant  consent  on  the  terms and  conditions  set forth in
                    subsection 17.4 of this Agree ment and such other reasonable
                    terms and conditions set forth in the Landlord's notice;

         17.3.2.    refuse to grant  consent for any of the reasons set forth in
                    subsection   17.5  of  this   Agreement  or  for  any  other
                    reasonable reason set forth in the Landlord's notice; or

                                      -20-

<PAGE>



         17.3.3.    elect to  terminate  the Term as of (a) the end of the third
                    full month after the Tenant has given notice of the Tenant's
                    desire to assign  or  sublet or (b) the  proposed  effective
                    date of the proposed assignment or sublease.

17.4.    The Landlord's consent to the Tenant's proposed assignment or sublease,
         if granted under subsection 17.3.1 of this Agreement,  shall be subject
         to all the following  terms and conditions  (and to any other terms and
         conditions permitted by that subsection): 

         17.4.1.    any  proposed   assignee  or  sublessee  shall,  by document
                    executed and delivered  forthwith to the Landlord,  agree to
                    assume and be bound by all the obligations of the Tenant set
                    forth in this Agreement;

         17.4.2.    the Tenant shall remain liable under this Agreement, jointly
                    and severally with any proposed  assignee or sublessee,  for
                    the timely  performance of all obligations of the Tenant set
                    forth in this Agreement;

         17.4.3.    the Tenant shall forthwith  deliver to the Landlord manually
                    executed  copies of all  documents  regarding  the  proposed
                    assignment or sublease and a written,  accurate and complete
                    description,  manually  executed  both by the Tenant and the
                    proposed  assignee  or  sublessee,  of any other  agreement,
                    arrangement  or  understanding  between them  regarding  the
                    same;

         17.4.4.    with  respect to any  consideration  or other thing of value
                    received or to be received by the Tenant in connection  with
                    any such assignment or sublease (other than those payable in
                    equal  monthly  installments  each month during the proposed
                    term of any such  assignment or sublease),  the Tenant shall
                    pay to the Landlord one-half of any such amount and one-half
                    of the fair market  value of any other thing of value within
                    10 days of receipt of same; and

         17.4.5.    with   respect  to  any   amount  payable  to  the Tenant in
                    equal  monthly  installments  each month during the proposed
                    term of any such  assignment or sublease in connection  with
                    such  assignment  or sublease,  which amount is in excess of
                    the  amount  which  bears  the  same  ratio  to the  monthly
                    installment  of Rent due from the Tenant as the usable floor
                    space of the Leased  Premises  subject to the  assignment or
                    sublease  bears to the  usable  floor  space  of the  entire
                    Leased  Premises,  the  Tenant  shall pay  one-half  of such
                    excess to the Landlord  together  with the Tenant's  monthly
                    installment of Rent.

17.5.    The Landlord's refusal to grant consent under subsection 17.3.2 of this
         Agreement shall not be deemed an unreasonable withholding of consent if
         based upon any of the following  reasons (or any other reason permitted
         by that  subsection):

         17.5.1.    the  Landlord  desires  to  take  one  of the other  actions
                    enumerated in subsection 17.3 of this Agreement;

         17.5.2.    there  is  already  another  assignee, sublessee or licensee
                    of all or a portion of the Leased Premises;

         17.5.3.    the proposed sublease is for a term of less than one year;

         17.5.4.    the proposed sublease is for a term which would expire after
                    the Term;

                                      -21-

<PAGE>



         17.5.5.    less than one   year  remains in the Term as of the proposed
                    effective date of the proposed assignment or sublease;

         17.5.6.    the  general  reputation,  financial  position or ability or
                    type of business  of, or the  anticipated  use of the Leased
                    Premises by, the proposed assignee or proposed subles see is
                    unsatisfactory to the Landlord or is inconsistent with those
                    of  tenants  of Other  Leased  Premises  or of the  Carnegie
                    Center Complex or inconsistent  with any commit ment made by
                    the Landlord to any such other tenant;

         17.5.7.    the proposed  consideration  to be paid to the Tenant during
                    any  period  of 12  months  is less  than the  amount of the
                    Market Rental Rate divided by the gross rentable floor space
                    of the Leased Premises and multiplied by that portion of the
                    gross rentable floor space of the Leased  Premises  proposed
                    to be subject to the proposed assignment or sublease; or

         17.5.8.    the gross  rentable floor space of the portion of the Leased
                    Premises proposed to be sublet is less than one-third of the
                    gross rentable floor space of the Leased Premises.

18.      Signs, Displays and Advertising.

18.1.   The  Tenant  shall have one sign  identifying  the  Landlord's  assigned
        number for the Leased  Premises at the principal  entrance to the Leased
        Premises.  The Tenant may identify  itself in or on each of: the sign at
        the principal  entrance to the Leased Premises,  the Building  directory
        and the  directory,  if any,  on the floor of the  Building on which the
        Leased Premises is located. All such signs, and the method and materials
        used in mounting and dismounting  them,  shall be in accordance with the
        Landlord's specifications.  All such signs shall be provided and mounted
        by the Landlord at the Landlord's expense,  except that the Tenant shall
        bear any  expense  of  identifying  itself on the sign at the  principal
        entrance to the Leased Premises.

18.2.   No  other  sign, advertisement,  fixture or display shall be used by the
        Tenant on the Property or in the Building or the Common Facilities.  Any
        signs other than those  specifically  permitted under subsection 18.1 of
        this  Agreement  shall  be  removed  promptly  by the  Tenant  or by the
        Landlord at the Tenant's expense.

19.      Quiet Enjoyment.

The  Landlord  is the owner of the  Building,  the  Property  and  those  Common
Facilities located on the Property.  The Landlord has the right and authority to
enter into and execute and deliver this Agreement with the Tenant. So long as an
Event of Default shall not have occurred, the Tenant shall and may peaceably and
quietly have,  hold and enjoy the Leased  Premises during the Term in accordance
with this Agreement.  

20.  Relocation.  

At any time and from time to time  during the Term,  on at least 30 days'  prior
notice to the Tenant,  but subject to the provisions of subsection  26.4 of this
agreement,  the  Landlord  shall  have the right to move the  Tenant  out of the
Leased  Premises and into premises  having at least equal floor space located in
the Building or in any other comparable  building located in the Carnegie Center
Complex for the duration of the Term,  subject to the express written consent of
State Mutual Life Assurance  Company of America,  as long as it is the holder of
the first mortgage on the Property. In the event the Landlord

                                      -22-

<PAGE>



exercises this right of relocation, the Landlord shall decorate the new premises
similarly to the Leased Premises and remove, relocate and reinstall the Tenant's
furniture,  trade fixtures,  furnishings and equipment, all at the sole cost and
expense of the Landlord.  When the substitute new premises are ready, the Tenant
shall  surrender  the  Leased  Premises.  Following  any such  relocation,  this
Agreement  shall continue in full force and effect except for the description of
the Leased  Premises,  the Building and the Property  which,  upon completion of
such  relocation,  shall be  deemed  amended  to  describe  the  substitute  new
premises,  building and property,  respectively,  to which the Tenant shall have
been  relocated  in  accordance  with  this  section  20 of the  Agreement.  

21.  Surrender.  

Upon  termination  of the Term, or at any other time at which the  Landlord,  by
virtue of any provision of this Agreement or otherwise has the right to re-enter
and  re-take  possession  of the Leased  Premises,  the Tenant  shall  surrender
possession of the Leased Premises;  remove from the Leased Premises all property
owned by the  Tenant or anyone  else other than the  Landlord;  remove  from the
Leased  Premises any  alterations,  improvements or other  modifications  to the
Leased  Premises  that the  Landlord  may  request by notice;  make any  repairs
required by such removal;  clean the Leased Premises;  leave the Leased Premises
in as good order and condition as it was upon the completion of any improvements
contemplated  by section 5 of this  Agreement,  ordinary  wear and use excepted;
return  all copies of all keys and  passes to the  Leased  Premises,  the Common
Facilities and the Building to the Landlord;  and receive the Landlord's written
acceptance of the Tenant's  surrender.  The Landlord shall not be deemed to have
accepted the  Tenant's  surrender  of the Leased  Premises  unless and until the
Landlord shall have executed and delivered the Landlord's  written acceptance of
surrender to the Tenant,  which shall not be  unreasonably  withheld or delayed.

22.  Events of Default.

The  occurrence  of any of the  following  events shall  constitute  an Event of
Default under this Agree ment:

22.1.       the  Tenant's  failure  to pay any  installment of Basic Rent or any
            amount of Additional Rent when it is first due;

22.2.       the Tenant's  failure  to perform any of its obligations  under this
            Agreement if such failure has caused,  or may cause,  loss or damage
            that can not promptly be cured by subsequent act of the Tenant;

22.3.       the   Tenant's  failure  to  complete  performance   of  any  of the
            Tenant's   obligations   under  this  Agreement  (other  than  those
            contemplated by subsections 22.1 and 22.2 of this Agreement)  within
            10 days after the  Landlord  shall  have given  notice to the Tenant
            specifying which of the Tenant's  obligations has not been performed
            and in what respects,  unless completion of performance  within such
            period of 10 days is not possible  using  diligence and  expedience,
            then within a reasonable  time of the  Landlord's  notice so long as
            the Tenant shall have commenced  substantial  performance within the
            first three days of such period of 10 days and shall have  continued
            to provide  substantial  performance,  diligently  and  expediently,
            through to completion of performance;

                                      -23-

<PAGE>



22.4.       the  discovery  that any  representation  made by the Tenant in this
            Agreement  shall have been  inaccurate or incomplete in any material
            respect  either  on the  date it was made or the date as of which it
            was made;

22.5.       the  sale,  transfer or  other  disposition  of any  interest of the
            Tenant in the Leased  Premises  by way of  execution  or other legal
            process;

22.6.       with  the  exception  of  those  of the  following  events  to which
            section 365 of the Bankruptcy  Code shall apply in the context of an
            office lease (in which case  subsection 22.7 of this Agreement shall
            apply):

          22.6.1.   the   Tenant's   becoming   a  "debtor,"  as  that  term  is
                    defined in section 101 of the Bankruptcy Code;

         22.6.2.    any time when either the value of the  Tenant's  liabilities
                    exceed  the value of the  Tenant's  assets or the  Tenant is
                    unable to pay its obligations as and when they  respectively
                    become due in the ordinary course of business;

         22.6.3.    the appointment of  a  receiver  or  trustee of the Tenant's
                    property or affairs; or

         22.6.4.    the  Tenant's  making  an  assignment for the benefit of, or
                    an arrangement with or among, creditors or filing a petition
                    in insolvency or for  reorganization  or for the appointment
                    of a receiver;

22.7.    in the  event of the  occurrence  of any of the  events  enumerated  in
         subsection  22.6  of  this  Agreement  to  which  section  365  of  the
         Bankruptcy  Code shall  apply in the  context of an office  lease,  the
         earlier of the bankruptcy  trustee's  rejection or deemed rejection (as
         those  terms are used in section  365 of the  Bankruptcy  Code) of this
         Agreement; or

22.8.    the Tenant's  abandoning the Leased Premises  before  expiration of the
         Term without the prior written consent of the Landlord.

23.      Rights and Remedies.

23.1.    Upon  the occurrence of an Event of Default the Landlord shall have all
         the following rights and remedies:

         23.1.1.    to  elect  to  terminate  the Term  by giving notice of such
                    election,  and the effective date thereof, to the Tenant and
                    to receive Termination Damages;

         23.1.2.    to elect to re-enter  and re-take  possession  of the Leased
                    Premises,  without  thereby  terminating the Term, by giving
                    notice of such election,  and the effective date thereof, to
                    the Tenant and to receive Re-Leasing Damages;

         23.1.3.    if  the  Tenant  remains   in   possession   of  the  Leased
                    Premises  after the Tenant's  obliga tion to  surrender  the
                    Leased Premises shall have arisen,  to remove the Tenant and
                    the  Tenant's  and any others'  possessions  from the Leased
                    Premises  by  any  of  the  follow  ing  means  without  any
                    liability to the Tenant therefor,  any such liability to the
                    Tenant  therefor  which might  otherwise  arise being hereby
                    waived  by  the  Tenant:   legal  proceedings   (summary  or
                    otherwise), writ of dispossession and any other means and to
                    receive  Holdover  Damages and, except in the  circumstances
                    contemplated by section 20 of this Agreement, to receive all
                    expenses incurred in removing the Tenant

                                      -24-

<PAGE>



                    and the Tenant's and any others' possessions from the Leased
                    Premises, and of storing such possessions if the Landlord so
                    elects;

         23.1.4.    to be awarded specific performance, temporary restraints and
                    preliminary and permanent injunctive relief regarding Events
                    of Default where the  Landlord's  rights and remedies at law
                    may be  inadequate,  without the necessity of proving actual
                    damages or the inadequacy of the rights and remedies at law;

         23.1.5.    to receive all expenses  incurred in  securing,  preserving,
                    maintaining  and  operating the Leased  Premises  during any
                    period of vacancy, in making repairs to the Leased Premises,
                    in  preparing  the Leased  Premises  for  re-leasing  and in
                    re-leasing the Leased Premises  including,  without limiting
                    the generality of the foregoing, any brokerage commissions;

         23.1.6.    to receive all legal expenses,  including  without  limiting
                    the generality of the forego ing,  attorneys'  fees incurred
                    in connection with pursuing any of the Landlord's rights and
                    remedies, including indemnification rights and remedies;

         23.1.7.    if the Landlord,  in its sole discretion,  elects to perform
                    any  obligation  of the Tenant under this  Agreement  (other
                    than the  obligation  to pay Rent)  which the Tenant has not
                    timely  performed,  to receive all  expenses  incurred in so
                    doing;

         23.1.8.    to  elect  to  pursue  any  legal  or  equitable  right  and
                    remedy  available  to the Landlord  under this  Agreement or
                    otherwise; and

         23.1.9.    to elect any combination,  or any sequential  combination of
                    any of the rights and remedies set forth in subsection  23.1
                    of this Agreement.

23.2.    In the event the  Landlord  elects  the right and  remedy  set forth in
         subsection 23.1.1 of this Agreement, Termination Damages shall be equal
         to the  amount  which,  at the time of actual  payment  thereof  to the
         Landlord,  is the sum of: 

         23.2.1.    all accrued but unpaid Rent;

         23.2.2.    the  present  value  (calculated  using  the  most  recently
                    available  (at the time of calcula  tion)  published  weekly
                    average yield on United States  Treasury  securities  having
                    maturities  comparable to the balance of the then  remaining
                    Term) of the sum of all payments of Rent  remaining  due (at
                    the time of calculation)  until the date the Term would have
                    expired (had there been no election to terminate it earlier)
                    less  the  present  value  (similarly   calculated)  of  all
                    payments of rent to be received  through the end of the Term
                    (had there been no election to terminate it earlier)  from a
                    lessee,  if  any,  of the  Leased  Premises  at the  time of
                    calculation  (and it shall be assumed  for  purposes of such
                    calculations  that (i) the amount of future  Additional Rent
                    due per  year  under  this  Agreement  will be  equal to the
                    average  Additional  Rent per month due  during  the 12 full
                    calendar months  immediately  preceding the date of any such
                    calculation, increas ing annually at a rate of eight percent
                    compounded, (ii) if any calculation is made before the first
                    anniversary  of the end of the No Pass Through  Period,  the
                    average  Additional  Rent due for any month after the end of
                    the No Pass Through  Period will be equal to nine percent of
                    the sum of the Base  Year  Operational  Expenses,  Base Year
                    Taxes and Tenant Electric  Charges  (considered on an annual
                    basis), (iii) if any

                                      -25-

<PAGE>



                    calculation  is made before the  beginning of the Base Year,
                    the  sum of  Base  Year  Taxes  and  Base  Year  Operational
                    Expenses  shall be  assumed  to be $6.50 per gross  rentable
                    square foot and (iv) if any  calculation  is made before the
                    end  of the  Base  Year,  Base  Year  Taxes  and  Base  Year
                    Operational  Expenses may be extrapolated  based on the year
                    to date experience of the Landlord);

         23.2.3.    the Landlord's reasonably estimated cost of  demolishing any
                    leasehold improvements to the Leased Premises; and

         23.2.4.    that  amount,  which as of the  occurrence  of the  Event of
                    Default, bears the same ratio to the costs, if any, incurred
                    by the Landlord (and not paid by the Tenant) in building out
                    the Leased  Premises in  accordance  with  section 5 of this
                    Agreement  as the  number  of months  remaining  in the Term
                    (immediately  before the occurrence of the Event of Default)
                    bears  to  the   number  of  months  in  the   entire   Term
                    (immediately before the occurrence of the Event of Default).

23.3.    In the event the  Landlord  elects  the right and  remedy  set forth in
         subsection 23.1.2 of this Agreement,  Re-Leasing Damages shall be equal
         to the Rent less any rent actually and timely  received by the Landlord
         from any lessee of the Leased Premises or any portion thereof,  payable
         at the  respective  times that Rent is payable under the Agreement plus
         the  cost,  if  any,  to the  Landlord  of  building  out or  otherwise
         preparing the Leased  Premises for, and leasing the Leased Premises to,
         any such lessee.

23.4.   In  the  event the  Landlord  elects  the right and  remedy set forth in
        subsection 23.1.3 of this Agreement, Holdover Damages shall mean damages
        at the rate per month or part  thereof  equal to the greater of: (a) one
        and one-half  times  one-twelfth of the then Market Rental Rate plus all
        Additional Rent as set forth in this Agreement or (b) double the average
        amount of all payments of Rent due under this  Agreement  during each of
        the last 12 full calendar months prior to the Landlord's so electing or,
        in the  event  the  Term  shall  have  terminated  by  expiration  under
        subsection 24.1.1 of this Agreement, the last full 12 calendar months of
        the  Term,  in  either  case  payable  in full on the  first day of each
        holdover month or part thereof.

23.5.   In connection  with  any summary proceeding to dispossess and remove the
        Tenant  from  the  Leased  Premises  under  subsection  23.1.3  of  this
        Agreement, the Tenant hereby waives:

         23.5.1.    any   notices   for  delivery  of  possession   thereof,  of
                    termination,  of demand for removal therefrom,  of the cause
                    therefor, to cease, to quit and all other notices that might
                    otherwise be required pursuant to 2 A N.J.S.A. sec. 18-53 et
                    seq.;

         23.5.2.    any  right  the  Tenant  might  otherwise  have  to  cause a
                    termination  of the  action or  proceeding  by paying to the
                    Landlord or into court or otherwise any Rent in arrears;

         23.5.3.    any right the  Tenant  might  otherwise  have to a period of
                    waiting between  issuance of any warrant in execution of any
                    judgment  for  possession  obtained by the  Landlord and the
                    execution thereof;

         23.5.4.    any right the Tenant  might  otherwise  have to  transfer or
                    remove  such  proceeding  from the court (or the  particular
                    division  or part of the  court) or other  forum in which it
                    shall have been instituted by the Landlord to another court,
                    division or part;

                                      -26-

<PAGE>



         23.5.5.    any right the  Tenant  might  otherwise  have to redeem  the
                    Tenant's former leasehold  interest between the entry of any
                    judgment  and  the  execution  of  any  warrant   issued  in
                    connection therewith by paying to the Landlord or into Court
                    or otherwise any Rent in arrears; and

         23.5.6.    any right the  Tenant  might  otherwise  have to appeal  any
                    judgment  awarding posses sion of the Leased Premises to the
                    Landlord.

23.6.   The  enumeration  of rights   and  remedies  in  this  section 23 of the
        Agreement  is not intended to be  exhaustive  or exclusive of any rights
        and remedies which might  otherwise be available to the Landlord,  or to
        force an election of one or more rights and remedies to the exclusion of
        others,  concurrently,  consecutively or sequentially.  On the contrary,
        each right and remedy  enumerated in this section 23 of the Agreement is
        intended to be cumulative with each other right and remedy enumerated in
        this  section 23 of the  Agreement  and with each other right and remedy
        that might otherwise be available to the Landlord;  and the selection of
        one or more of such rights and  remedies at any time shall not be deemed
        to prevent  resort to one or more others of such rights and  remedies at
        the  same  time or a  subsequent  time,  even  with  regard  to the same
        occurrence sought to be remedied.

23.7.   It is  expressly  understood and  agreed that the Landlord shall have no
        duty to mitigate damages. In the event the Landlord elects the right and
        remedy  set forth in  subsection  23.1.2 of this  Agreement,  Re-Leasing
        Damages  shall be equal to the Rent less any rent  actually  and  timely
        received by the Landlord  from any lessee of the Leased  Premises or any
        portion  thereof,  payable at the respective  times that Rent is payable
        under the  Agreement  plus the cost, if any, to the Landlord of building
        out or  otherwise  preparing  the Leased  Premises  for, and leasing the
        Leased Premises to, any such lessee.  The Landlord may relet some or all
        of the Leased Premises but shall have no duty to do so. The Tenant shall
        retain its rights to sublet or assign the Leased  Premises,  or portions
        thereof,  pursuant  to Article 17 hereof  except to the extent  that the
        Landlord  shall have  already  relet the same which shall  abrogate  the
        Tenant's rights, pro tanto.

24. Termination of the Term.

24.1.    The  Term  shall terminate upon the earliest of the following events to
         occur:

         24.1.1.    expiration of the Term;

         24.1.2.    in  connection  with  a  transaction contemplated by section
                    16 of this  Agreement,  the later of (a) the  vesting of the
                    acquiring  party's  right to  possession or (b) the Tenant's
                    vacating the Leased Premises;

         24.1.3.    under the  circumstances  contemplated by subsection 15.1 of
                    this  Agreement,  upon the Tenant's  giving prompt notice of
                    the failure of the Landlord to give, on a timely basis,  the
                    notice  contemplated by subsection  15.1.2 of this Agreement
                    and that the Tenant  desires  termination of the Term (which
                    termination shall be effective as of the date of the subject
                    casualty  with  respect  to  those  portions  of the  Leased
                    Premises  rendered  untenantable  and as of the  date of the
                    Tenant's giving notice with respect to those portions of the
                    Leased Premises which were not rendered untenantable);

         24.1.4.    under the  circumstances  contemplated by subsection 15.1 of
                    this  Agreement,  upon the expiration of 45 additional  days
                    (without the Landlord's completion of restoration in

                                                           -27-

<PAGE>



                    the interim) after the Tenant shall have given prompt notice
                    that the Landlord has not restored the Leased  Premises on a
                    timely basis and that the Tenant desires  termination of the
                    Term (which termination shall be effective as of the date of
                    the subject  casualty with respect to those  portions of the
                    Leased Premises rendered  untenantable and as of the date of
                    the Tenant's giving notice with respect to those portions of
                    the Leased Premises which were not rendered untenantable);

         24.1.5.    the  effective  date of any election by the  Landlord  under
                    subsection  17.3.3  of this  Agreement  in  response  to the
                    Tenant's  notice  of the  Tenant's  desire  to  assign  this
                    Agreement  or to  sublet  all or a  portion  of  the  Leased
                    Premises; or

         24.1.6.    the  effective  date  of any  election  by the  Landlord  to
                    terminate   the  Term  under   subsection   23.1.1  of  this
                    Agreement.

24.2.    No  termination  of the Term  shall have the  effect of  releasing  the
         Tenant from any obligation or liability theretofore or thereby incurred
         and,  until the Tenant shall have  surrendered  the Leased  Premises in
         accordance  with section 21 of this  Agreement,  from any obligation or
         liability thereafter incurred.

25.      Mortgage and Underlying Lease Priority.

This  Agreement  and the  estate,  interest  and rights  hereby  created for the
benefit of the Tenant are,  and shall  always be,  subordinate  to any  mortgage
(other  than a  mortgage  created  by the  Tenant or a sale,  transfer  or other
disposition  by the Tenant in the nature of a security  interest in violation of
subsections  17.1.4  and  22.5,  respectively,  of this  Agreement)  already  or
afterwards placed on the Property,  the Common  Facilities,  the Building or any
estate or interest  therein  including,  without  limiting the generality of the
foregoing,  any new mortgage or any mortgage extension,  renewal,  modification,
consolidation,  replacement,  supplement or substitution. This Agreement and the
estate,  interest and rights  hereby  created for the benefit of the Tenant are,
and shall always be,  subordinate to any ground lease already or afterwards made
with regard to the Property,  the Common Facilities,  the Building or any estate
or interest therein including, without limiting the generality of the foregoing,
any new  ground  lease or any ground  lease  extension,  renewal,  modification,
consolidation,  replacement,  supplement or substitution. The provisions of this
section 25 of the Agreement shall be  self-effecting;  and no further instrument
shall be necessary to effect any such  subordination.  Nevertheless,  the Tenant
hereby consents that any mortgagee or mortgagee's  successor in interest may, at
any  time and from  time to time,  by  notice  to the  Tenant,  subordinate  its
mortgage  to the estate and  interest  created by this  Agreement;  and upon the
giving of such notice,  the subject mortgage shall be deemed  subordinate to the
estate and interest created by this Agreement regardless of the respective times
of  execution or delivery of either or of recording  the subject  mortgage.  

26.  Transfer by Landlord.  

26.1.   The Landlord shall have the right at any time and from time to time to
        sell,  transfer,  lease or  otherwise  dispose  of the  Carnegie  Center
        Complex,  the Property,  the Common Facilities or the Building or any of
        the Landlord's  interests therein, or to assign this Agreement or any of
        the Landlord's rights thereunder.

26.2.   Upon  giving notice of the occurrence of any transaction contemplated by
        subsection  26.1 of  this  Agreement,  the  Landlord  shall  thereby  be
        relieved of any obligation that might otherwise exist

                                      -28-

<PAGE>



         under  this  Agreement  with  respect  to  periods  subsequent  to  the
         effective  date of any such  transaction.  If, in  connection  with any
         transaction  contemplated  by  subsection  26.1 of this  Agreement  the
         Landlord transfers, or makes allowance for, any Security Deposit of the
         Tenant and gives notice of that fact to the Tenant,  the Landlord shall
         thereby be relieved of any further obligation to the Tenant with regard
         to any such Security  Deposit;  and the Tenant shall look solely to the
         transferee with respect to any such Security Deposit.

26.3.    In the  event of the  occurrence  of any  transaction  contemplated  by
         subsection  26.1 of this  Agreement  the Tenant,  upon written  request
         therefor from the transferee,  shall attorn to and become the tenant of
         such  transferee  upon  the  terms  and  conditions  set  forth in this
         Agreement.

26.4.   Notwithstanding  anything  to  the  contrary  that  may  be set forth in
        subsections  26.1,  26.2 and 26.3 of this  Agreement,  in the  event any
        mortgage  contemplated  by section 25 of this Agree ment is  enforced by
        the respective  mortgagee  pursuant to remedies provided in the mortgage
        or  otherwise  provided by law or equity and any person  succeeds to the
        interest of the Landlord as a result of, or in connection with, any such
        enforcement,  the Tenant  shall,  upon the request of such  successor in
        interest,  automatically  attorn  to  and  become  the  Tenant  of  such
        successor in interest  without any change in the terms or  provisions of
        this Agreement, except that such successor in interest shall not be

         (a)        liable for any act or omission of the Landlord; or

         (b)        liable  for  the  return  of  the  Security  Deposit  unless
                    actually  received  by  such  motgagee  or  such   successor
                    in interest; or

         (c)        subject to any counterclaims, credits, rights to deduct from
                    rent,  offsets  or  defenses  which the  Tenant  might  have
                    against the Landlord; or

         (d)        bound  by any  payment  of  Rent or  Additional  Rent to the
                    Landlord in advance for more than each current month; or

         (e)        bound by any agreement, amendment,  modification, renewal or
                    extension (other than pursuant to the exercise by the Tenant
                    of  an  option  therefor  contained  in  this  Agree  ment),
                    termination,   surrender,   release,   waiver,  consent,  or
                    approval,  or the  exercise by the Landlord of any option or
                    right  (including  without  limitation the right to relocate
                    the Tenant contained in Section 20 of this  Agreement),  any
                    of  which  actions  is taken or done  with  respect  to this
                    Agreement  without first obtaining the prior written consent
                    thereto by such mortgagee; or

         (f)        bound by any payment of any consideration or compensation of
                    any kind to the Landlord  which may relate in any way to any
                    of the  actions  referred to in the immedi  ately  preceding
                    clause (e) or any payment of any damages or other amounts to
                    the Landlord relating in any way to any breach or default by
                    the Tenant under this agreement.

         Upon the  request of such  successor  in  interest,  the  Tenant  shall
         execute,  acknowledge and deliver any instrument(s)  confirming any and
         all of the matters referred to in this Subsection 26.4.

                                      -29-

<PAGE>



26.5.    If this  Agreement and the estate,  interest and rights hereby  created
         for the benefit of the Tenant are ever subject and  subordinate  to any
         ground lease contemplated by section 25 of this Agreement:

         26.5.1.  upon  the  expiration  or  earlier  termination  of  the  term
                    of any such ground lease before the  termination of the Term
                    under this Agreement, the Tenant shall attorn to, and become
                    the Tenant of, the lessor  under any such  ground  lease and
                    recognize  such lessor as the Landlord  under this Agreement
                    for the balance of the Term; and

         26.5.2.    such  expiration or earlier  termination  of the term of any
                    such  ground  lease  shall  have no effect on the Term under
                    this Agreement.

27.      Indemnification.

27.1.    The Tenant shall,  and hereby does,  indemnify the Landlord against any
         and all liabilities,  obligations,  damages, penalties,  claims, costs,
         charges and expenses including,  without limiting the generality of the
         foregoing,  expenses of investigation,  defense and enforcement thereof
         or of the  obligation  set forth in this  section  27 of the  Agreement
         including, without limiting the generality of the foregoing, attorneys'
         fees, imposed on or incurred by the Landlord in connec tion with any of
         the following matters which occurs during the Term: 

         27.1.1.    any  matter,  cause  or  thing   arising  out  of  the  use,
                    occupancy,  control or management of the Leased  Premises or
                    any   portion   thereof   which  is  not  caused   directly,
                    exclusively  and  entirely by the  Landlord's  active  gross
                    negligence or intentional  act without the  intervention  of
                    any other cause or contributing factor whatsoever;

         27.1.2.    any negligence or intentional act on the part of the  Tenant
                    or any of its employees, other agents or Guests;

         27.1.3.    any  accident,  injury or damage to any  person or  property
                    occurring  in or  about  the  Leased  Premises  which is not
                    caused directly, exclusively and entirely by the Land lord's
                    active  gross  negligence  or  intentional  act  without the
                    intervention  of any  other  cause  or  contributing  factor
                    whatsoever;

         27.1.4.    any  representation  made by the  Tenant  in this  Agreement
                    shall have been  inaccurate  or  incomplete  in any material
                    respect  either  on the  date it was  made or the date as of
                    which it was made;

         27.1.5.    the  imposition of any  mechanic's,  materialman's  or other
                    lien on the Property,  the Common Facilities,  the Building,
                    the Leased  Premises or any portion of any of the foregoing,
                    or the filing of any notice of  intention to obtain any such
                    lien,  in connection  with any  alteration,  improvement  or
                    other modification of the Leased Premises made or authorized
                    by the Tenant  (which  indemnification  obligation  shall be
                    deemed to  include  the  Tenant's  obligations  set forth in
                    subsection 12.2.4.3 of this Agreement); or
         27.1.6.    any  failure  on the part of the Tenant to perform or comply

                    with  any  obligation  of  the  Tenant  set  forth  in  this
                    Agreement.

27.2.    Payment of  indemnification  claims by the Tenant to the Landlord shall
         be due upon the Landlord's giving notice thereof to the Tenant.

                                      -30-

<PAGE>



27.3.   The  Landlord  shall  promptly  give  notice of any claim  asserted,  or
        action or  proceeding  commenced,  against  it as to which it intends to
        claim  indemnification  from the Tenant and, upon notice from the Tenant
        so  requesting,  shall  forward  to the  Tenant  copies  of all claim or
        litigation  documents  received by it.  Upon  receipt of such notice the
        Tenant may, by notice to the Landlord,  participate  therein and, to the
        extent it may desire,  assume the defense  thereof  through  independent
        counsel  selected  by the  Tenant  and  reasonably  satisfactory  to the
        Landlord.  The  Landlord  shall  not  be  bound  by  any  compromise  or
        settlement  of any such claim,  action or  proceeding  without its prior
        written consent.

28. Parties' Liability.

28.1.    None of the  following  occurrences  shall  constitute a breach of this
         Agreement by the  Landlord,  a  termination  of the Term,  an active or
         constructive  eviction or an occurrence requiring an abatement of Rent:

         28.1.1.    the  inability  of  the  Landlord  to provide any utility or
                    service to be  provided by the  Landlord,  as  described  in
                    section 8 of this  Agreement  which is due to causes  beyond
                    the  Landlord's   control,  or  to  necessary  or  advisable
                    improvements,  maintenance, repairs or emergency, so long as
                    the Landlord uses reasonable efforts and diligence under the
                    circumstances to restore the interrupted service or utility;

         28.1.2.    any  improvement,  modification,  alteration or other change
                    made to the  Carnegie  Center  Complex,  the  Property,  the
                    Building   or  the  Common   Facilities   by  the   Landlord
                    consistently  with the Landlord's  obligations  set forth in
                    subsection 13.2 of this Agreement; and

         28.1.3.    any change in any Federal, state or local law or ordinance.

 28.2.  Except   for  the   commencement,  duration   or   termination   of  the
        Term (other than under the circumstances contemplated by subsection 15.1
        of this Agreement),  the Tenant's  obligation to make timely payments of
        Rent, the Tenant's  obligation to maintain certain insurance coverage in
        effect,  the  Tenant's  failure to perform any of its other  obligations
        under this  Agreement if such failure has caused loss or damage that can
        not  promptly  be cured by  subsequent  act of the Tenant and the period
        within which any Option to Renew or any other type of option or optional
        right  exercisable  by the Tenant must be exercised,  any period of time
        during which the Landlord or the Tenant is prevented from performing any
        of its respective  obligations under this Agreement because of fire, any
        other casualty or catastrophe, strikes, lockouts, civil commo tion, acts
        of God or the public enemy,  governmental  prohibitions  or preemptions,
        embargoes  or  inability  to obtain  labor or material  due to shortage,
        governmental regulation or prohibition,  shall be added to the time when
        such performance is otherwise required under this Agreement.

28.3.    In the event the Landlord is an individual, partnership, joint venture,
         association  or a participant  in a joint tenancy or tenancy in common,
         the Landlord, the partners,  venturers,  members and joint owners shall
         not have any personal  liability or  obligation  under or in connection
         with this  Agreement or the  Tenant's  use and  occupancy of the Leased
         Premises;  but recourse shall be limited  exclusively to the Landlord's
         interest in the Building.

28.4.    If, at any time during the Term,  the payment or collection of any Rent
         otherwise  due  under  this  Agreement  shall  be  limited,  frozen  or
         otherwise subjected to a moratorium by applicable law,

                                      -31-

<PAGE>



         and such limitation,  freeze or other moratorium shall  subsequently be
         lifted,  whether  before or after  the  termination  of the Term,  such
         aggregate  amount  of Rent as shall  not have  been  paid or  collected
         during  the Term on  account  of any such  limitation,  freeze or other
         moratorium,  shall thereupon be due and payable at once. There shall be
         added to the  maximum  period of any  otherwise  applicable  statute of
         limitation the entire period during which any such  limitation,  freeze
         or other moratorium shall have been in effect.

28.5.    If this Agreement is executed by more than one person as Tenant,  their
         liability  under  this  Agreement  and in  connection  with the use and
         occupancy of the Leased Premises shall be joint and several.

28.6.    In the event any rate of  interest,  or other  charge in the  nature of
         interest,  calculated as set forth in this Agreement  would lead to the
         imposition  of a  rate  of  interest  in  excess  of the  maximum  rate
         permitted by  applicable  usury law,  only the maximum  rate  permitted
         shall be charged and collected.

28.7.    The rule of construction  that any ambiguities that may be contained in
         any contract shall be construed against the party drafting the contract
         shall be inapplicable in construing this Agreement.

29.      Security Deposit.

The  Tenant  shall pay to the  Landlord  upon  execution  and  delivery  of this
Agreement the sum of $12,158.13 as a security deposit to be held by the Landlord
as security for the Tenant's  performance of all the Tenant's  obligations under
this Agreement. The Landlord may commingle the Security Deposit with its general
funds. Any interest earned on the Security Deposit shall belong to the Landlord.
The Tenant shall not encumber the Security  Deposit.  The Landlord,  in its sole
discretion,  may apply the Security  Deposit to cure any Event of Default  under
this Agreement.  If any such application is made, upon notice by the Landlord to
the Tenant,  the Tenant shall promptly  replace the amount so applied.  If there
has been no Event of Default,  within 30 days after  termination of the Term the
Landlord shall return the entire balance of the Security  Deposit to the Tenant.
The Tenant  will not look to any  foreclosing  mortgagee  of the  Property,  the
Building,  the Common  Facilities or any interest therein for such return of the
balance of the Security Deposit,  unless the mortgagee has expressly assumed the
Landlord's obligations under this Agreement or has actually received the balance
of the Security Deposit.

30.  Representations.  

The Tenant hereby represents and warrants that:

30.1.   its  Standard  Industrial  Classification (SIC) code is 3970 and it will
        promptly  give  notice  of any  change  therein  during  the Term to the
        Landlord;

30.2.   no  broker  or other agent has shown the Leased Premises or the Building
        to the  Tenant,  or brought  either to the  Tenant's  attention,  except
        Princeton Realty Advisors, whose entire commission therefor is set forth
        in a separate document and which commission the Tenant  understands will
        be paid by the Landlord directly to the person named;

30.3.   the  execution  and delivery of, the  consummation  of the  transactions
        contemplated by and the performance of all its obligations  under,  this
        Agreement by the Tenant have been duly and

                                      -32-

<PAGE>



        validly  authorized by its general  partners,  to the extent required by
        their  partnership  agreement  and  applicable  law,  if the Tenant is a
        partnership  or,  if  the  Tenant  is a  corporation,  by its  board  of
        directors and, if necessary, by its stockholders at meetings duly called
        and  held on  proper  notice  for  that  purpose  at  which  there  were
        respective quorums present and voting throughout; and no other approval,
        partnership,  corporate,  governmental  or  otherwise,  is  required  to
        authorize  any  of the  foregoing  or to  give  effect  to the  Tenant's
        execution and delivery of this Agreement; and


30.4.   the execution and delivery  of, the  consummation  of  the  transactions
        contemplated by and the performance of all its obligations  under,  this
        Agreement by the Tenant will not result in a breach or violation  of, or
        constitute a default  under,  the  provisions  of any statute,  charter,
        certificate of incorporation  or bylaws or partnership  agreement of the
        Tenant or any  affiliate of the Tenant,  as presently in effect,  or any
        indenture, mortgage, lease, deed of trust, other agreement,  instrument,
        franchise,  permit,  license,  decree, order, notice,  judgment, rule or
        order to or of which the  Tenant  or any  affiliate  of the  Tenant is a
        party, a subject or a recipient or by which the Tenant, any affiliate of
        the Tenant or any of their  respective  properties  and other  assets is
        bound.  

31.  Reservation  in Favor of  Tenant.

Neither the  Landlord's  forwarding a copy of this  document to any  prospective
tenant  nor any other act on the part of the  Landlord  prior to  execution  and
delivery of this  Agreement by the Landlord  shall give rise to any  implication
that any prospective tenant has a reservation, an option to lease or an outstand
ing offer to lease any premises.  

32. Tenant's Certificates and Mortgagee Notice Requirements.

32.1.   Promptly  upon  request  of  the  Landlord  at  any time or from time to
        time,  but  in no  event  more  than  five  days  after  the  Landlord's
        respective request, the Tenant shall execute, acknowledge and deliver to
        the  Landlord  or  its  designee  an  estoppel  or  other   certificate,
        satisfactory  in  form  and  substance  to the  Landlord  and any of its
        mortgagees,  ground  lessors or lessees or trans  ferees or  prospective
        mortgagees,  ground lessors or lessees or  transferees,  with respect to
        any of or all the following  matters,  which certificate shall be in the
        form  attached  hereto as Exhibit G if so requested by State Mutual Life
        Assurance  Company  of  America  while it  remains  a  mortgagee  of the
        Property,  the Building or any interest  therein:

        32.1.1. whether this Agreement is then in full force and effect;

        32.1.2. whether  this  Agreement   has  not  been   amended,   modified,
                superseded, canceled, repudiated or revoked;

        32.1.3. whether   the   Landlord   has  satisfactorily   completed   all
                construction   work,  if  any,   required  of  the  Landlord  or
                contractors  selected and retained by the Landlord in connection
                with readying the Leased Premises for occupancy by the Tenant in
                accordance with section 5 of this Agreement;

        32.1.4. whether   the  Tenant  is  then  in  actual  possession  of  the
                Leased Premises;

        32.1.5. whether  the  Tenant   then  has  no  defenses or  counterclaims
                under this  Agreement or otherwise  against the Landlord or with
                respect to the Leased Premises;

                                      -33-

<PAGE>



         32.1.6.    whether  Landlord  is   not then in breach of this Agreement
                    in any respect;

         32.1.7.    whether  the  Tenant  then   has   no   knowledge   of   any
                    assignment  of this  Agreement,  the pledging or granting of
                    any security  interest in this  Agreement or in Rent due and
                    to become due under this Agreement;

         32.1.8.    whether  Rent  is  not  then  accruing  under this Agreement
                    in accordance with its terms;

         32.1.9.    whether any Rent is not then in arrears;

         32.1.10.   whether  Rent  due  or  to  become  due under this Agreement
                    has not been prepaid by more than one month;

         32.1.11.   if  the  response  to  any  of the  foregoing  matters is in
                    the negative,  a  specification  of all the precise  reasons
                    that  necessitated  the negative  response in each instance;
                    and

         32.1.12.   any other matter reasonably requested by the Landlord or any
                    of its mortgagees,  ground lessors or lessees or transferees
                    or  prospective  mortgagees,  ground  lessors  or lessees or
                    transferees,  including,  without limiting the generality of
                    the foregoing,  such information as the Landlord may request
                    for purposes of assuring compliance with the Industrial Site
                    Recovery  Act (13  N.J.S.A. sec. 1K-6 et seq.), as it may be
                    amended,  and any other applicable  Federal,  state or local
                    statute, ordinance, rule, regulation or order concerned with
                    environmental matters.

32.2.    If, in connection  with the  Landlord's  or a prospective  transferee's
         obtaining financing or refinancing of the Carnegie Center Complex,  the
         Property,  the Building, the Common Facili ties, any portion thereof or
         any interest  therein,  the Landlord or a  prospective  lender shall so
         request,  the Tenant shall  furnish to the  requesting  party within 15
         days of the  request:  

         32.2.1.    its  written  consent  to  any  requested  modifications  of
                    this Agreement  provided  that, in each such  instance,  the
                    requested  modification does not increase the Rent otherwise
                    due or, in the reasonable judgment of the Tenant,  otherwise
                    materially increase the obligations of the Tenant under this
                    Agreement  or  materially   adversely  affect  the  Tenant's
                    leasehold  interest  created  hereby or the Tenant's use and
                    enjoyment   of   the   Leased   Premises   (except   in  the
                    circumstances contemplated by section 16 of this Agreement);
                    and

         32.2.2.    summary  financial   information   regarding  its  financial
                    position  as of the  close  of its most  recently  completed
                    fiscal year and its most recently  completed  interim fiscal
                    period  and  regarding  its  results of  operations  for the
                    periods  then ended and  compara ble year  earlier  periods,
                    certified  by  Tenant's  chief  financial  officer  to  be a
                    complete,  accurate  and fair  presentation  of the  summary
                    financial information purporting to be set forth therein.

32.3.    If the Landlord or any of its mortgagees  gives notice to the Tenant of
         any of their  respective  names and  addresses  from time to time,  the
         Tenant shall give notice to each such mortgagee of any notice of breach
         or default previously or afterwards given by the Tenant to the Landlord
         under this  Agreement  and provide in such notice that if the  Landlord
         has not cured such breach or default within any permissible cure period
         then such mortgagee shall have the greater of (a) an additional  period
         of 30 days or (b) if such default cannot practically be cured by such

                                      -34-

<PAGE>



         mortgagee within such period,  such additional  period as is reasonable
         under the  circumstances,  within  which such  mortgagee  may cure such
         default. Upon request of the Landlord at any time or from time to time,
         the Tenant shall  execute,  acknowledge  and deliver to the Landlord or
         its  designee  an  acknowledgment  of  receipt of any such  notice,  an
         acknowledgment of receipt of any notice of assignment of this Agreement
         or rights  hereunder by the Landlord to any of its  mortgagees  and the
         Tenant's  agreement to the foregoing effect on the respective forms, if
         any, furnished by the Landlord or the respective mortgagees.

32.4.    Approximately (i) 90 days prior to the termination of the Term and (ii)
         30 days prior to any relocation of the Tenant from the Leased  Premises
         (as constituted on the Commencement Date), the Tenant shall obtain from
         the New Jersey Department of Environmental  Protection,  and deliver to
         the   Landlord,   the   Department's   unconditional   certificate   of
         non-applicability  or approval of the Tenant's negative  declaration or
         clean-up plan,  together with copies of all documents  furnished to the
         Department in connection with obtaining such certificate or approval.

33.      Waiver of Jury Trial and Arbitration.

The parties hereby waive any right they might  otherwise have to a trial by jury
in  connection  with any  dispute  arising  out of or in  connection  with  this
Agreement  or the use and  occupancy  of the Leased  Premises;  and they  hereby
consent  to  arbitration  of any such  dispute  in  Princeton,  New  Jersey,  in
accordance with the rules for commercial arbitration of the American Arbitration
Association  or successor  organization,  except that the Landlord,  in its sole
discretion, may, with respect to any dispute involving either (i) the Landlord's
right to re-enter  and  re-take  possession  of the Leased  Premises or (ii) the
determination  of money damages  following the occurrence of an Event of Default
under this  Agreement,  elect to pursue any of or all its rights in any court of
competent  jurisdiction.  Judgment upon any arbitration  award may be entered in
any court of competent jurisdiction.

34.      Severability.

In the event that any provision of this  Agreement,  or the  application  of any
provision  in any  instance,  shall  be  conclusively  determined  by a court of
competent jurisdiction to be illegal, invalid or otherwise  unenforceable,  such
determination  shall not affect the validity or enforceability of the balance of
this Agreement.


                                      -35-

<PAGE>



5.       Notices.

All notices contemplated by, permitted or required by this Agreement shall be in
writing. All notices required by this Agreement shall be personally delivered or
forwarded by certified mail--return receipt requested, addressed to the intended
party at its address  first set forth above  (adding,  in the case of notices to
the Landlord after the Commencement Date, "Attention: Lease Administration") or,
in the case of notices to the Tenant  during the Term or any other period during
which the Tenant shall be in  possession of the Leased  Premises,  at the Leased
Premises.  Either party may from time to time change the address  prescribed  in
this  Agreement for notices to it by notice to the other.  All notices  required
under  this  Agreement  shall be  deemed  given  upon  their  deposit,  properly
addressed and postage prepaid,  in a postal depository or upon personal delivery
to the intended party, regardless of whether delivery shall be refused.

36.      Captions.

Captions have been  inserted at the beginning of each section of this  Agreement
for  convenience  of  reference  only and such  captions  shall not  affect  the
construction or interpretation of any such section of this Agreement.

37.      Counterparts.

This Agreement may be executed in more than one counterpart, each of which shall
constitute an original of this Agreement but all of which, taken together, shall
constitute one and the same Agree ment.

38.      Applicable Law.

This Agreement and the obligations of the parties hereunder shall be governed by
and construed in accordance with the laws of the State of New Jersey.

39.      Exclusive Benefit.

Except  as may be  otherwise  specifically  set  forth in this  Agreement,  this
Agreement is made exclu  sively for the benefit of the parties  hereto and their
permitted  assignees  and no one else shall be entitled to any right,  remedy or
claim by  reason  of any  provision  of this  Agreement.  

40.  Successors.  

This  Agreement  shall be binding upon the parties  hereto and their  respective
successors and assigns.

41.  Amendments.

This Agreement contains the entire agreement of the parties hereto, subsumes all
prior  discussions and negotiations and, except as may otherwise be specifically
set forth in this  Agreement,  this  Agreement  may not be amended or  otherwise
modified except by a writing signed by all the parties to this Agreement.

42.  Waiver.  

Except as may otherwise be specifically set forth in this Agreement, the failure
of any party at any time or times to require  performance  of any  provision  of
this  Agreement  shall in no manner  affect the right at a later time to enforce
the same. No waiver by any party of any condition, or of the breach of any

                                      -36-

<PAGE>



term, covenant,  representation or warranty set forth in this Agreement, whether
by conduct or otherwise,  in any one or more instances  shall be deemed to be or
construed as a further or continuing  waiver of any such condition or breach, or
as a waiver of any other condition or of the breach of any other term, covenant,
representation  or warranty set forth in this  Agreement.  The Landlord's  accep
tance of, or endorsement  on, any partial payment of Rent or any late payment of
Rent from the Tenant  shall not operate as a waiver of the  Landlord's  right to
the balance of the Rent due on a timely basis  regardless  of any writing to the
contrary on, or  accompanying,  the Tenant's  partial  payment or the Landlord's
putative acquiescence  therein. 43. Course of Performance.  No course of dealing
or  performance  by the parties,  or any of them,  shall be  admissible  for the
purpose of obtaining an  interpretation  or  construction  of this  Agreement at
variance with the express language of the Agreement itself.

                                      -37-

<PAGE>



IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed
as of the date first above written.

LANDLORD:

CARNEGIE 214 ASSOCIATES LIMITED PARTNERSHIP

By :  214 Capital Corp.

By:       /s/ Alan B. Landis
         ------------------------- 
         Alan B. Landis, President


TENANT:

PALATIN TECHNOLOGIES, INC.


By:        /s/ Edward J. Quilty
         ------------------------- 
         Edward J. Quilty
         Chairman and CEO


                                      -38-

<PAGE>



                                    EXHIBIT A

                       LEASED PREMISES FLOOR SPACE DIAGRAM










                           [GROUND FLOOR PLAN DIAGRAM]











                                      -39-

<PAGE>



                                    EXHIBIT B
                        DESCRIPTION OF LOT 76, BLOCK S-9
                              WEST WINDSOR TOWNSHIP
                            MERCER COUNTY, NEW JERSEY

All that certain lot, parcel, or tract of land situate and lying in the Township
of West  Windsor,  County  of  Mercer  and State of New  Jersey  and being  more
particularly bounded and described as follows:

BEGINNING  at a point,  said point being  distant  the  following  five  courses
(designated A through E) from the  intersection  of the southerly line of Roszel
Road (60' R.O.W.) and the westerly line of Lot 61, Block S-9 as shown on a Major
Subdivision Map entitled "Preliminary-Final Major Subdivision,  Lot 7, Block S-9
situated in West Windsor  Township,  Mercer  County,  New  Jersey,"  prepared by
Lynch,  Carmody,  Giuliano & Karol,  P.A.,  filed in the Mercer  County  Clerk's
Office on February 18, 1983, as Map No. 2513, and running thence:

(A)      South 44 13' 07" East, a distance of 324.42 feet to a point; thence

(B)      South 58 57' 14" West, a distance of 716.08 feet to a point; thence

(C)      South 16 48' 22" West, a distance of 198.72 feet to a point; thence

(D)      South 49 39' 04" West, a distance of 583.64 feet to a point; thence

(E) South 42 48' 22" West, a distance of 10.00 feet to the aforementioned  point
of BEGINNING, and running thence from the point of BEGINNING:

1.       Along a curve to the right,  said curve having a radius of 250.00  feet
         and an arc length of 196.35 feet, to a point of tangency; thence

2.       South 87 48' 22" West, a distance of 340.00 feet to a point; thence

3.       North 02 11' 38"  West, a  distance  of  394.25  feet  to  a  point  of
         curvature; thence

4.       Along  a curve to the left,  said curve  having a radius of 200.00 feet
         and an arc length of 157.08 feet, to a point of tangency; thence

5.       North 47 11' 38" West, a distance of 295.16 feet to a point; thence

6.       North 42 48' 22" East, a distance of 615.00 feet to a point; thence

7.       South 47 11' 38" East, a distance of 279.19 feet to a point; thence

8.       South 02 11' 38" East, a distance of 756.83 feet to a point; thence

9.       South 47 11' 38" East, a distance of 214.65 feet to the point and place
         of BEGINNING.

The above described  parcel of land is intended to be the same as shown on a map
entitled "Preliminary-Final Major Subdivision,  Lots 7 & 20, Block S-9, situated
in West  Windsor  Township,  Mercer  County,  New  Jersey,"  prepared  by Lynch,
Carmody,  Giuliano & Karol, P.A., dated October 8, 1984, and revised to December
10, 1985,  and filed in the Mercer County  Clerk's office on October 30, 1985 as
Map No. 2730.

The above  description is in accordance with a survey prepared by Fellows Read &
Associates, Inc. dated January 9, 1986, revised to January 30, 1986.



                                      -40-

<PAGE>



                                    EXHIBIT C

                                   WORK LETTER

The Building's  structure is a three-story  office building of Construction Type
2C with a steel  frame,  a metal  deck  floor  system,  a granite  and  concrete
exterior facade and insulated  glass. The floors will sustain a live load of 100
pounds per square foot of usable  floor space plus an allowance of 20 pounds per
square foot for partitions and has a typical bay size of 30 feet by 30 feet.

Among other Common  Facilities,  the Building contains two men's and two women's
bathrooms on each floor, two drinking  fountains on each floor and two hydraulic
elevators with a capacity of 2,500 pounds each and has Parking  Facilities  with
approximately 500 lined parking spaces.

As used in this Work Letter,  "building  standard" shall mean the type and grade
of  material,  equipment  or device  designated  by the Landlord as standard for
leased  premises in the  Building.  Any work  performed  in the  Building  shall
conform to such standard.



                                      -41-

<PAGE>



                                    EXHIBIT D
                         BUILDING RULES AND REGULATIONS

The following are the Building Rules and Regulations  adopted in accordance with
subsection  7.2.3 of the  Agreement  of which this  exhibit  is a part;  and the
Tenant and the  Tenant's  employees,  other  agents and Guests shall comply with
these Building Rules and Regulations:

1. The sidewalks,  driveways,  entrances,  passages,  courts,  lobby,  esplanade
areas, plazas,  elevators,  vestibules,  stairways,  corridors,  halls and other
Common Facilities shall not be obstructed or encum bered or used for any purpose
other than ingress and egress to and from the Leased Premises.  The Tenant shall
not permit or suffer any of its employees,  other agents or Guests to congregate
in any of the said areas. No door mat of any kind whatsoever  shall be placed or
left in any public hall or outside any entry door of the Leased Premises.  

2. No awnings or other projections shall be attached to the outside walls of the
Building. No curtains,  drapes,  blinds, shades or screens shall be attached to,
hung in or used in  connection  with any window or door of the  Leased  Premises
without the prior written  consent of Landlord.  If such consent is given,  such
curtains,  drapes, blinds, shades or screens shall be of a quality, type, design
and color, and attached in the manner, approved by Landlord.

3. Except as
otherwise  specifically  provided in subsection 18.1 of the Agreement,  no sign,
insignia,  advertisement,  object, notice or other lettering shall be exhibited,
inscribed,  painted  or  affixed so as to be  visible  from  outside  the Leased
Premises or the Building. In the event of the violation of the foregoing by the
Tenant,  the Landlord may remove same without any  liability  and may charge the
expense incurred in such removal to the Tenant. 

4. The sashes, doors, skylights,  windows, and doors that reflect or admit light
and air into the halls, passageways or other public places in the Building shall
not be covered or obstructed and no bottles,  parcels or other articles shall be
placed on the window sills.

5. No showcase or other  articles  shall be placed in front of or affixed to any
part of the Building or the Common Facilities.

6. The lavatories,  water and wash closets and other plumbing fixtures shall not
be used for any  purposes  other  than those for which  they were  designed  and
constructed, and no sweepings, rubbish, rags, acids or other substances shall be
thrown or deposited therein. All damages resulting from any misuse thereof shall
be  repaired  at the  expense of the  Tenant  that  permitted  or  suffered  the
violation hereof by the Tenant, the Tenant's employees, other agents or Guests.

7. The Tenant shall not mark, paint, drill into or in any way deface any part of
the Leased Premises,  the Building,  the Common  Facilities or the Property.  No
boring, cutting or stringing of wires shall be permitted,  except with the prior
written  consent of the Landlord,  and as the Landlord may direct.  Linoleum and
other resilient floor coverings shall be laid so that the same shall not come in
direct contact with the floor of the Leased  Premises;  and if linoleum or other
resilient  floor  coverings are desired,  an interlining of builder's  deadening
felt shall be first affixed to the floor by a paste or

                                      -42-

<PAGE>



other material that is, and will remain,  soluble in water. The use of cement or
other adhesive material that either is not, or will not remain, soluble in water
is prohibited. 

8. No bicycles,  vehicles, animals, reptiles, fish or birds of any kind shall be
brought into or kept in or about the Leased Premises.

9. No noise including,  without limiting the generality of the foregoing,  music
or the playing of musical instruments, recordings, radio or television which, in
the  reasonable  judgment of  Landlord,  might  disturb  tenants of Other Leased
Premises  shall be made or  permitted  by the Tenant.  Nothing  shall be done or
permitted  in the Leased  Premises by the Tenant which would impair or interfere
with the use or  enjoyment  of Other  Leased  Premises  by any  tenant  thereof.
Nothing  shall be thrown out of the  doors,  windows  or  skylights  or down the
passageways of the Building.

10. The Tenant shall not manufacture  any commodity,  or prepare or dispense any
foods or beverages,  tobacco,  flowers or other  commodities or articles without
the prior written consent of the Landlord.

11.  Duplicates  of keys and passes  distributed  to the Tenant by the  Landlord
shall not be made.  The Tenant  shall  provide  appropriate  security  for keys.
Nothing shall be done to render any lock inoperable by the Building Grand Master
Key. No lock shall be installed  without the Landlord's  prior written  consent;
and any lock so installed  shall be operable by the  Building  Grand Master Key.
Upon  termination of the Term, all keys,  passes and duplicates  provided by the
Landlord to the Tenant, or otherwise  procured by the Tenant,  shall be returned
to the Landlord. Any failure to comply with the foregoing which requires changes
in locks,  new or additional  keys,  passes or duplicates or other services of a
locksmith shall be paid by the Tenant.

12.  All  deliveries  and  removals,  and the  carrying  in or out of any safes,
freight, furniture, packages, boxes, crates or any other object or matter of any
description  shall take place  during  such  hours,  in such  manner and in such
elevators and  passageways  as the Landlord may determine from time to time. The
Landlord reserves the right to inspect all objects and matter being brought into
the Building or the Common  Facilities  and to exclude from the Building and the
Common  Facilities  all objects and matter that  violates any of these  Building
Rules and Regulations or that are contraband. The Landlord may (but shall not be
obligated to) require any person  leaving the Building or the Common  Facilities
with any package or object or matter from the Leased  Premises to establish  his
authority from the Tenant to do so. The  establishment and enforcement of such a
requirement  shall  not  impose  any  responsibility  on the  Landlord  for  the
protection  of the  Tenant  against  the  removal  of  property  from the Leased
Premises.  The  Landlord  shall not be liable to the Tenant for  damages or loss
arising from the admis sion,  exclusion or ejection of any person to or from the
Leased Premises or the Building or the Common Facilities under this rule.

13. The Tenant shall not place any object in any portion of the Building that is
in excess of the safe carrying or designed load capacity of the structure.

14. The Landlord shall have the right to prohibit any  advertising or display of
any  identifying  sign by the Tenant which in the  Landlord's  judgment tends to
impair the  reputation  of the  Building  or its  desirability;  and, on written
notice from the  Landlord,  the Tenant shall  refrain from or  discontinue  such
advertising or display of such identifying sign.

                                      -43-

<PAGE>



15. The Landlord  reserves the right to exclude from the Building and the Common
Facilities during hours other than Regular Business Hours all persons who do not
present a pass thereto  signed by both the Landlord and the Tenant.  All persons
entering or leaving the  Building or the Common  Facilities  during  hours other
than  Regular  Business may be required to sign a register.  The  Landlord  will
furnish  passes to persons for whom the Tenant  requests  same in  writing.  The
establishment  and  enforcement  of such a  requirement  shall  not  impose  any
responsibility  on  the  Landlord  for  the  protection  of the  Tenant  against
unauthorized  entry of persons.  

16. The Tenant, before closing and leaving the Leased Premises at any time shall
see that all lights and  appliances  generating  heat  (other  than the  heating
system) are turned off. All entrance doors to the Leased  Premises shall be left
locked by the Tenant when the Leased  Premises  are not in use. At any time when
the Building or the Common Facilities are locked during hours other than Regular
Business  Hours,  the  Building  and the Common  Facilities  locks  shall not be
defeated by any means, such as by leaving a door ajar.

17. No person shall go upon the roof of the Building  without the prior  written
consent of the Landlord.

18. Any  requirements of the Tenant may be attended to only upon  application at
the office of the  Building.  The  Landlord and its agents shall not perform any
work or do any work or do anything outside of the Landlord's  obligations  under
the  Agreement  except  upon  special  instructions  from the  Landlord on terms
acceptable to the Landlord and the Tenant.

19.  Canvassing,  soliciting  and  peddling  in  the  Building  and  the  Common
Facilities are prohibited and the Tenant shall cooperate to prevent same.

20. There shall not be used in any space, or in the public halls or other Common
Facilities of the Building, in connection with the moving or delivery or receipt
of safes, freight,  furniture,  packages, boxes, crates, paper, office material,
or any other matter or thing,  any hand trucks or dollies  except those equipped
with rubber tires,  side guards and such other  safeguards as the Landlord shall
require. No hand trucks shall be used in passenger  elevators,  and no passenger
elevators   shall  be  used  for  the   moving,   delivery  or  receipt  of  the
aforementioned  articles.  In  connection  with moving in or out any  furniture,
furnishings, equipment, heavy articles and heavy packages, the Tenant shall take
such  precautions as may be necessary to prevent  excessive wear and tear in the
Building's Common Facilities and the Leased Premises including, without limiting
the generality of the foregoing, floor and wall treatments.

21. The Tenant shall not cause or permit any odors of cooking or other processes
or any unusual or  objectional  odors to emanate from the Leased  Premises which
might  constitute a Nuisance.  No cooking  shall be done in the Leased  Premises
other than as specifically permitted in the Agreement.

22.  The  Landlord  reserves  the  right not to  enforce  any  Building  Rule or
Regulation  against any tenants of Other Leased Premises.  The Landlord reserves
the right to rescind,  amend or waive any Building Rule and Regulation  when, in
the Landlord's  reasonable  judgment,  it appears necessary or desirable for the
reputation,  safety,  care or appearance of the Building or the  preservation of
good order therein or the operation of the Building or the comfort of tenants or
others in the Building. No rescission,  amendment or waiver of any Building Rule
and  Regulation in favor of one tenant shall operate as a rescission,  amendment
or waiver in favor of any other tenant.

                                      -44-

<PAGE>



                                    EXHIBIT E
                      DEFINITIONS AND INDEX OF DEFINITIONS

In  accordance  with section 1 of the Agreement of which this exhibit is a part,
throughout  the Agree  ment the  following  terms  and  phrases  shall  have the
meanings set forth or referred to below: 

1.       "Additional  Rent" means  all amounts,  other  than  Basic Rent and any
          Security Deposit,  required to be paid by the Tenant   to the Landlord
         in accordance with this Agreement.

2.       "Agreement" means this Lease and Lease Agreement (including  exhibits),
         as it may have been amended.

3.       "Annual  Amortized  Capital   Expenditure"  means  the  payment  amount
         determined  as an  annuity in arrears  using the cost  incurred  by the
         Landlord for any Capital  Expenditure as the present value,  the number
         of years of its useful life (not  exceeding  10 years)  selected by the
         Landlord in accordance  with generally  applied real estate  accounting
         practice  as the number of periods and the Base Rate in effect when the
         respective improvement is first placed into service plus two additional
         percentage points as the annual rate of interest.

4.       "Base  Rate"  means  the  prime  commercial  lending  rate  per year as
         announced  from  time to time by The  Chase  Manhattan  Bank  (National
         Association) at its principal office in New York City.

5.       "Base Year" means  the  full   calendar   year  1997  with   respect to
         Operational Expenses and Taxes. 

6.       "Base  Year  Operational Expenses" means  actual  Operational  Expenses
         incurred by the Landlord during the Base Year.

7.       "Base Year Taxes" means the product of the final assessed value, as the
         same may  subsequently  be adjusted in any appeal of the tax assessor's
         valuation,  of the Property, the Building and any other improvements on
         the  Property in the Base Year and the  Municipality's  lowest tax rate
         for office  buildings  and the  property  on which they stand in effect
         during the Base Year.

8.       "Basic Rent" is defined in subsection 3.2 of this Agreement.

9.       "Building"  means the office building  erected on the Property which is
         commonly known as 214 Carnegie Center,  Princeton, New Jersey 08540, as
         it may, in the Landlord's  sole  discretion,  be increased,  decreased,
         modified, altered or otherwise changed from time to time before, during
         or after the Term. As the Building is presently constructed it consists
         of 149,043 gross rentable square feet of floor space.

10.      "Capital  Expenditure" is defined in subsection 10.3 of this Agreement.

11.      "Commencement  Date" is  defined  in section 4 of this  Agreement.  

12.      "Common Facilities"  means   the  areas,  facilities  and  improvements
         provided  by   the  Landlord  in  the   Building   (except  the  Leased
         Premises and the Other Leased Premises)and on the Property,  including,
         without   limiting   the   generality  of  the  foregoing,  the Parking
         Facilities and driveways on the Property,  for    non-exclusive  use by
         the Tenant in accordance  with  subsection 2.2 of  this  Agreement,  as
         they  may,  in  the  Landlord's   sole   discretion,   be    increased,
         decreased, modified, altered  or  otherwise changed  from time  to time
         before,  during or after the Term,  and subject to rights which  may be
         granted  to  the  major  tenant  to  utilize  the  lobby  as  a  common
         reception area.

                                      -45-

<PAGE>




13.      "Common Walls" means  those  walls  which  separate the Leased Premises
         from Other Leased Premises.

14.      "Electric Charges" means all the supplying utility's charges for, or in
         connection with, furnishing electricity including charges determined by
         actual usage, any seasonal adjustments, demand charges, energy charges,
         energy adjustment charges and any other charges, howsoever denominated,
         of the  supplying  utility,  including  sales and excise  taxes and the
         like.

15.      "Event of Default" is defined in section 22 of this Agreement.

16.      "Expiring Term" means, when used in the context of any Option to Renew,
         the  Term as it is then  scheduled  to  expire  (immediately  prior  to
         exercise of the next available Option to Renew).

17.      The Tenant's "Guests" shall mean the Tenant's  licensees,  invitees and
         all others  in, on or about the  Leased  Premises,  the  Building,  the
         Common  Facilities or the Property,  either at the Tenant's  express or
         implied  request or  invitation  or for the  purpose of  soliciting  or
         visiting the Tenant.

18.      A "History of  Recurring  Events of Default"  means the  occurrence  of
         three or more Events of Default (whether or not cured by the Tenant) in
         any period of 12 months.

19.      "Holdover Damages" is defined in subsection 23.4 of this Agreement.

20.      The  "Index"  means   the "all  items"  index  figure  for the New York
         Northeastern  New Jersey   average of the Consumer  Price Index for all
         urban wage  earners and  clerical  workers  which uses a base period of
         1982-84=100,  published  by the United States  Department of Labor,  so
         long as it continues to  be  published.  If the Index is not  published
         for a period of three   consecutive  months,   or if its base period is
         changed,  the term "Index" shall mean that index,  as nearly equivalent
         in purpose,  function  and  coverage as  practicable   to the  original
         Index,  which the  Landlord  shall  have  designated  by  notice to the
         Tenant.

21.      "Initial Term" means the period so designated in subsection 4.1 of this
         Agreement.

22.      "Initial Year" means  the  first 12 full calendar months of the Initial
         Term.

23.      "Landlord"  means the person so  designated  at  the  beginning of this
         Agreement  and  those  successors  to the  Landlord's  interest  in the
         Property  and/or  the  Landlord's  rights  and obligations  under  this
         Agreement contemplated by section 26 of this Agreement.

24.      "Leased  Premises"  means  that portion of the interior of the Building
         (as viewed from the  interior of the Leased  Premises)   bounded by the
         interior sides of the unfinished floor and the finished  ceiling on the
         first floor (as the floors have been  designated  by the   Landlord) of
         the Building,  the centers of all Common Walls and the  exterior  sides
         of all walls other than Common Walls, the outline of which  floor space
         is designated  on the diagram set forth in Exhibit A attached   hereto,
         which  portion  contains  3,336  square feet of usable floor  space and
         3,970 square feet of gross rentable floor space; and references  within
         this  Agreement to the gross rentable floor space and the usable  floor
         space, respectively,  of the Leased Premises shall mean the  respective
         quantities herein specified.

                                      -46-

<PAGE>




25.      "Legal Holidays" means New Year's Day,  Presidents' Day,  Memorial Day,
         Independence Day, Labor Day, Thanksgiving Day and Christmas Day.

26.      "Market  Rental  Rate"  means,  at the  time of  reference,  the  gross
         rentable floor space of the Leased  Premises  multiplied by the greater
         of:  (a) that  annual  rate of  Basic  Rent  per  square  foot of gross
         rentable  floor space which is then being  quoted by the  Landlord  for
         comparable Other Leased Premises (or would then be quoted if comparable
         Other Leased  Premises were then  available) or (b) that annual rate of
         Basic  Rent per square  foot of gross  rentable  floor  space in effect
         during the Expiring Term.

27.      "Municipality" means the Township of West Windsor in Mercer County, New
         Jersey,  or any  successor  municipality  with  jurisdiction  over  the
         Property.

28.      "No Pass Through Period" means, in the context of Operational  Expenses
         and Taxes, the period beginning on the Commencement  Date and ending on
         December 31, 1997.

29.      "Nuisance"  means any condition or  occurrence  which  unreasonably  or
         materially  interferes  with the  authorized  use and  enjoyment of the
         Other Leased Premises and the Common  Facilities by any tenant of Other
         Leased  Premises or by any person  authorized  to use any Other  Leased
         Premises or Common  Facilities or with the  authorized use of any other
         areas, buildings or other improvements in the Carnegie Center Complex.

30.      "Operational   Expenses"  is  defined  in   subsection   10.2  of  this
         Agreement.

31.      "Option to Renew" is defined in  subsection  6.1 of this  Agreement.  

32.      "Other Leased  Premises" means  all premises within the Building,  with
         the  exception of  the Leased  Premises,  that are, or are available to
         be, leased to tenants or prospective tenants, respectively.

33.      "Parking  Facilities"  means the parking area adjacent to the Building,
         containing the approxi mate number of lined parking spaces set forth in
         the Work Letter, which parking area is provided as Common Facilities

34.      "Person" includes an individual, a corporation, a partnership, a trust,
         an  estate,  an  unincorpo  rated  group of  persons  and any  group of
         persons.

35.      "Property"  means the parcel of land, as it may, in the Landlord's sole
         discretion,  be increased,  decreased,  modified,  altered or otherwise
         changed  from time to time before,  during or after the Term,  on which
         the  Building  is (or is  about  to be)  erected.  As the  Property  is
         presently  constituted,  it is more particularly described in Exhibit B
         attached hereto.

36.      "Regular  Business Hours" means 8:00 A.M. to 6:00 P.M.,  Monday through
         Friday, except on Legal Holidays.

37.      "Re-Leasing Damages" is defined in subsection 23.3.

38.      "Renewal  Term"  means,  at the time of  reference,  any portion of the
         Term,  other than the Initial Term, as to which the Tenant has properly
         exercised  an  Option  to Renew  which  Option  to  Renew  has not been
         rescinded in accordance with subsection 6.4.1 of this Agreement.

                                      -47-

<PAGE>



39.      "Rent" means Basic Rent and Additional Rent.

40.      "Security Deposit" is designated in section 29 of this Agreement.

41.      "Target Date" means, upon execution and delivery of this Agreement, the
         then  estimated  Commencement  Date which is hereby  established  to be
         August 1, 1997.

42.       "Taxes"  means,  in any calendar  year,  the aggregate  amount of real
          property  taxes,  assess-  ments and sewer  rents,  rates and charges,
          state and local taxes,  transit  taxes and every other  govern  mental
          charge, whether general or special,  ordinary or extraordinary (except
          corporate  franchise  taxes and taxes  imposed  on, or  computed  as a
          function  of, net income or net  profits  from all  sources and except
          taxes charged,  assessed or levied  exclusively on the Leased Premises
          or  arising  exclusively  from the  Tenant's  occupancy  of the Leased
          Premises)  charged,  assessed or levied by any taxing  authority  with
          respect to the Property,  the Building,  the Common Facilities and any
          other  improvements on the Property and an allocable  portion of Taxes
          with respect to other portions of the Carnegie  Center  Complex,  less
          any refunds or rebates (net of expenses incurred in obtaining any such
          refunds or rebates) of Taxes actually  received by the Landlord during
          such  calendar year with respect to any period during the Term for the
          benefit  of the  Tenant,  tenants  of Other  Leased  Premises  and the
          Landlord.  If during the Term there  shall be a change in the means or
          methods of taxing real  property  generally in effect at the beginning
          of the Term and another  type of tax or method of  taxation  should be
          substituted in whole or in part for, or in lieu of, Taxes, the amounts
          calculated  under such other types of tax or by such other  methods of
          taxation  shall  also be deemed to be  Taxes.  Until  such time as the
          actual amount of Taxes for any calendar year becomes known, the amount
          thereof  shall be the  Landlord's  estimate of Taxes for that calendar
          year.

43.       "Tenant"  means the  person so  designated  at the  beginning  of this
          Agreement.

44.       "Tenant  Electric  Charges" means (a) during Regular  Business  Hours,
          Electric  Charges  attributable  to the Tenant's use of electricity in
          the Leased  Premises for purposes other than heating,  ventilation and
          air  conditioning  provided to the Leased  Premises by the Landlord in
          accordance  with  subsection  8.2.4 of this  Agreement  and (b) during
          other than Regular  Business Hours, a charge at the rate of $75.00 per
          hour or partial hour of use plus Electric Charges  attributable to the
          Tenant's use of  electricity  in the Leased  Premises for all purposes
          including, without limiting the generality of the foregoing,  heating,
          ventilation and air conditioning.

45.       "Tenant's Share" of any amount means 2.664%.

46.       "Term"  means the Initial  Term plus,  at the time of  reference,  any
          Renewal Term.

47.       "Termination Damages" is defined in subsection 23.2 of this Agreement.

48.       "Traffic    Plan"   is   defined   in    subsection    7.3   of   this
          Agreement."Utilities  Expenses"  means  Electric  Charges  (other than
          Tenant  Electric  Charges) and all charges for any other fuel that may
          be used in providing  electricity and services  powered by electricity
          that the  Landlord  provides  in  accordance  with  section  8 of this
          Agreement to the Building, the Leased Premises, Other Leased Premises,
          the Common  Facilities  and the Property,  including  sales and excise
          taxes and the like.

                                      -48-

<PAGE>



49.      "Utilities Expenses" means Electric Charges (other than Tenant Electric
         Charges)  and  all  charges  for any  other  fuel  that  may be used in
         providing  electricity  and services  powered by  electricity  that the
         Landlord provides in accordance with section 8 of this Agreement to the
         Building,  the  Leased  Premises,  Other  Leased  Premises,  the Common
         Facilities and the Property,  including  sales and excise taxes and the
         like.

50.      "Work Letter" means Exhibit C attached hereto which generally describes
         the type of construc tion of the Building  and,  unless the Tenant Plan
         does not require any such respective  improve ment, those  improvements
         the  Landlord  will provide or install in the Leased  Premises  without
         installation charge to the Tenant in connection with the preparation of
         the Leased Premises contemplated by section 5 of this Agreement.


                                      -49-

<PAGE>



                                    EXHIBIT F
                 STATE MUTUAL LIFE ASSURANCE COMPANY OF AMERICA
                          FORM OF ESTOPPEL CERTIFICATE

STATE MUTUAL LIFE ASSURANCE COMPANY OF AMERICA
440 Lincoln Street
Worcester, MA  01605

Gentlemen:

This  instrument is being  furnished to State Mutual Life  Assurance  Company of
America ("Lender") by -------------------  ("Tenant"), which is the tenant under
a lease (the "Lease") dated --------------- from CARNEGIE 214 ASSOCIATES LIMITED
PARTNERSHIP ("Landlord"),  pertaining to and covering a portion, as such portion
is specifically  described in the Lease (the "Demised  Premises"),  of that real
estate commonly designated as 214 Carnegie Center, Princeton, Mercer County, New
Jersey (the "Property" or "Building"),  such real estate being more specifically
described in Exhibit "A" attached hereto.

As an  inducement  to Lender to make a loan (the "Loan") as permanent  financing
for the Property,  with the  intention of having  Lender rely  thereon,  and for
other good and valuable consideration,  Tenant hereby warrants and represents to
Lender and agrees with Lender as follows:


     (a)  That the Lease has not been  amended or  modified,  except as follows:
          and  is  in   -------------------------   full  force  and  effect  as
          originally  executed or as so amended,  whichever is appropriate,  and
          that  neither  Landlord  nor the Tenant is in  default in any  respect
          under any terms of the Lease;


     (b)  The commencement date of the term of the Lease was  ------------,  and
          the term of the Lease will expire on  -------------  , unless extended
          or sooner terminated as provided in the Lease;

     (c)  That Tenant is in possession of the Demised Premises and that Landlord
          has complied  fully and completely  with all of Landlord's  covenants,
          warranties and other  undertakings and obligations  under the Lease to
          this date,  including,  without limitation,  those with respect to (i)
          the  construction,  character,  condition  and location of the Demised
          Premises;  (ii)  improvements,  tenant's  spaces and the common  areas
          situated on the Property; (iii) other tenancies,  occupancies,  stores
          or  businesses  on the  Property;  (iv) any  property  adjacent to the
          Property;   (v)  parking  and  access;   and  (vi)  the  provision  of
          maintenance and services under the Lease,  with the result that Tenant
          is fully  obligated to pay, and is paying,  the rent and other charges
          due thereunder,  and is fully obligated to perform, and is performing,
          all of the other obligations of Tenant under the Lease without current
          claim or counterclaim, offset, defense or otherwise;

     (d)  That Tenant has not and will not make any  prepayment  of rental under
          the  Lease  for more  than one (1)  month in  advance  of the due date
          thereof,   and  that  there  are   currently  no  offsets,   defenses,
          counterclaims or credits against the rentals due thereunder;

     (e)  That  Tenant  has not  received  notice  and has no  knowledge  of any
          assignment,  hypothecation  or pledge  of the  rents or of  Landlord's
          interest under the Lease other than ----------------.

     (f)  That  Tenant  understands  and  acknowledges  that  (i)Landlord  shall
          execute a conditional assignment of the Lease in favor of Lender; (ii)
          notwithstanding  said assignment,  all rental payments under the Lease
          shall be paid as heretofore stated and in accordance with the terms of
          the Lease  until and unless  Tenant is  notified  to the  contrary  in
          writing by Lender;  (iii) under the conditions of said  assignment and
          after the date  thereof,  it is  expressly  agreed  that,  unless  the
          written  consent  of  Lender  be first  obtained,  no rents  are to be
          collected more than one month in advance of the due date thereof,  and
          no  alterations,   modification,  amendments,  terminations,  waivers,
          consents,  approvals  or other  actions  whatsoever  are to be made or
          become  effective with respect to the Lease except as permitted  under
          the terms of said conditional assignment; and (iv) the interest of the
          Landlord in the Lease shall be assigned to Lender solely as additional
          security  for said  Loan and  Lender  assumes  no duty,  liability  or
          obligation under the Lease,  either by virtue of said assignment,  the
          exercise  of  remedies  thereunder,  or by any  subsequent  receipt or
          collection  of rents  thereunder or any other sums due under the terms
          of the Lease;

                                      -50-

<PAGE>


     (g)  That Lender  shall not be (i) liable for any action or omission of any
          person or party  who may be  Landlord  under  the Lease  prior to your
          acquisition of title to the Property by foreclosure or otherwise; (ii)
          subject to any offsets or defenses  which  Tenant may have against any
          such prior  Landlord;  or (iii)  liable for the return of any security
          deposit unless Lender actually receives such deposit;

     (h)  That Tenant has not  subordinated by separate  written  instrument its
          interest under the Lease to any mortgage,  deed of trust or other lien
          on title to the Property.

     (i)  That  Tenant  has paid in full for all labor and  materials  and other
          services in connection  with Tenant's  construction  work and Tenant's
          other work in the Demised Premises,  so that no lien by reason thereof
          may attach against the Landlord's  interest in the Demised Premises or
          the Property of which they are a part and that  Tenant,  to the extent
          required  by the terms of the  Lease,  has been  fully  reimbursed  by
          Landlord for all improvements made by Tenant to the Demised Premises.

     (j)  In   consideration  of  the  premises  and  other  good  and  valuable
          consideration to the Tenant by Lender,  the receipt and sufficiency of
          which are hereby  acknowledged,  Tenant  further agrees with Lender as
          follows:  In the event of any  default  by  Landlord  under the Lease,
          Tenant shall  promptly send to Lender at the address  hereinabove  set
          forth a copy of any notice of such default  sent to  Landlord,  in the
          same manner as such notice to Landlord is sent,  and in such event and
          prior to the exercise by Tenant of any of its rights or remedies under
          the Lease or otherwise  with respect to such default,  Lender shall be
          permitted to cure such default  within the period of time during which
          Landlord  would be  permitted to cure such default as set forth in the
          Lease.

     (k)  Tenant  agrees  that,  with  respect to any  successor  to  Landlord's
          interest in the Property,  to look solely to such successor's interest
          in the Property for  recovery of any judgment  from such  successor to
          Landlord; it being specifically agreed that no successor to Landlord's
          interest in the Property shall ever be personally  liable for any such
          judgment.

     (l)  This Certificate shall inure to the benefit of Lender,  its successors
          and  assigns,  and shall be binding  upon Tenant and  Tenant's  heirs,
          legal representatives,  successors and assigns. This Certificate shall
          not be  deemed  to  alter  or  modify  any of the  terms,  conditions,
          covenants or  obligations of the Lease,  except to the extent,  if any
          specifically set forth herein.


EXECUTED this ________ day of ____________________, 19__.

ATTEST:


______________________________     BY:___________________________

                                      -51-








                             LEASE AGREEMENT BETWEEN








                           WHC-SIX REAL ESTATE, L.P.,
                         A DELAWARE LIMITED PARTNERSHIP,
                                  AS LANDLORD,

                                       AND


                           PALATIN TECHNOLOGIES, INC.,
                             A DELAWARE CORPORATION,
                                    AS TENANT



                              DATED MARCH 13, 1997





<PAGE>
                                TABLE OF CONTENTS



Article             Caption                                  Page


1     Lease Grant. . . . . . . . . . . . . . . . . . . . . . . .1

2     Term . . . . . . . . . . . . . . . . . . . . . . . . . . .1

3     Rent . . . . . . . . . . . . . . . . . . . . . . . . . . .2
     (a) Basic Rent. . . . . . . . . . . . . . . . . . . . . . .2
     (b) Payment . . . . . . . . . . . . . . . . . . . . . . . .2
     (c) Operating Expenses. . . . . . . . . . . . . . . . . . .3

4     Delinquent Payment; Handling Charges . . . . . . . . . . .5

5     Security Deposit . . . . . . . . . . . . . . . . . . . . .5

6     Landlord's Obligations . . . . . . . . . . . . . . . . . .6
     (a) Services. . . . . . . . . . . . . . . . . . . . . . . .6
     (b) Excess Utility Use. . . . . . . . . . . . . . . . . . .7
     (c) Restoration of Services; Abatement. . . . . . . . . . .7

7     Improvements; Alterations; Repairs; Maintenance. . . . . .8
     (a) Improvements; Alterations . . . . . . . . . . . . . . .8
     (b) Repairs; Maintenance. . . . . . . . . . . . . . . . .  8
     (c) Performance of Work . . . . . . . . . . . . . . . . . .9
     (d) Mechanic's Liens. . . . . . . . . . . . . . . . . . . .9

8     Use. . . . . . . . . . . . . . . . . . . . . . . . . . . .9

9     Assignment and Subletting. . . . . . . . . . . . . . . . 10
     (a) Transfers; Consent. . . . . . . . . . . . . . . . . . 10
     (b) Cancellation. . . . . . . . . . . . . . . . . . . . . 11
     (c) Additional Compensation . . . . . . . . . . . . . . . 11

10    Insurance; Waivers; Subrogation; Indemnity . . . . . . . 11
     (a) Insurance . . . . . . . . . . . . . . . . . . . . . . 11
     (b) Waiver of Negligence; No Subrogation. . . . . . . . . 12
     (c) Indemnity . . . . . . . . . . . . . . . . . . . . . . 12


<PAGE>

11    Subordination Attornment; Notice to Landlord's
      Mortgagee. . . . . . . . . . . . . . . . . . . . . . . . 12
     (a) Subordination . . . . . . . . . . . . . . . . . . . . 12
     (b) . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
     (c) Attornment. . . . . . . . . . . . . . . . . . . . . . 13
     (d) Notice to Landlord's Mortgagee. . . . . . . . . . . . 13

12    Rules and Regulations. . . . . . . . . . . . . . . . . . 13

13    Condemnation . . . . . . . . . . . . . . . . . . . . . . 13
     (a) Total Taking. . . . . . . . . . . . . . . . . . . . . 13
     (b) Partial Taking - Tenant's Rights. . . . . . . . . . . 13
     (c) Partial Taking - Landlord's Rights. . . . . . . . . . 14
     (d) Award . . . . . . . . . . . . . . . . . . . . . . . . 14

14    Fire or Other Casualty . . . . . . . . . . . . . . . . . 14
     (a) Repair Estimate . . . . . . . . . . . . . . . . . . . 14
     (b) Landlord's and Tenant's Rights. . . . . . . . . . . . 15
     (c) Landlord's Rights . . . . . . . . . . . . . . . . . . 15
     (d) Repair Obligation . . . . . . . . . . . . . . . . . . 15

15    Taxes. . . . . . . . . . . . . . . . . . . . . . . . . . 15

16    Events of Default. . . . . . . . . . . . . . . . . . . . 15

17    Remedies . . . . . . . . . . . . . . . . . . . . . . . . 16

18    Payment by Tenant; Non-Waiver. . . . . . . . . . . . . . 17
     (a) Payment by Tenant . . . . . . . . . . . . . . . . . . 17
     (b) No Waiver . . . . . . . . . . . . . . . . . . . . . . 17

19    Landlord's Lien. . . . . . . . . . . . . . . . . . . . . 17

20    Surrender of Premises. . . . . . . . . . . . . . . . . . 17

21    Holding Over . . . . . . . . . . . . . . . . . . . . . . 18

22    Certain Rights Reserved by Landlord. . . . . . . . . . . 18

23    Intentionally Omitted. . . . . . . . . . . . . . . . . . 19

24    Miscellaneous. . . . . . . . . . . . . . . . . . . . . . 19
     (a) Landlord's Transfer . . . . . . . . . . . . . . . . . 19
     (b) Landlord's Liability. . . . . . . . . . . . . . . . . 19

<PAGE>

     (c) Force Majeure . . . . . . . . . . . . . . . . . . . . 19
     (d) Brokerage . . . . . . . . . . . . . . . . . . . . . . 19
     (e) Estoppel Certificates . . . . . . . . . . . . . . . . 19
     (f) Notices . . . . . . . . . . . . . . . . . . . . . . . 20
     (g) Separability. . . . . . . . . . . . . . . . . . . . . 20
     (h) Amendments; and Binding Effect. . . . . . . . . . . . 20
     (i) Quiet Enjoyment . . . . . . . . . . . . . . . . . . . 20
     (j) No Merger . . . . . . . . . . . . . . . . . . . . . . 20
     (k) No Offer. . . . . . . . . . . . . . . . . . . . . . . 20
     (l) Entire Agreement. . . . . . . . . . . . . . . . . . . 21
     (m) Waiver of Jury Trial. . . . . . . . . . . . . . . . . 21
     (n) Governing Law . . . . . . . . . . . . . . . . . . . . 21
     (o) Joint and Several Liability . . . . . . . . . . . . . 21
     (p) Financial Reports . . . . . . . . . . . . . . . . . . 21
     (q) Landlord's Fees . . . . . . . . . . . . . . . . . . . 21
     (r) Intentionally Omitted . . . . . . . . . . . . . . . . 21
     (s) Confidentiality . . . . . . . . . . . . . . . . . . . 21
     (t) List of Exhibits. . . . . . . . . . . . . . . . . . . 22

25    Other Provisions . . . . . . . . . . . . . . . . . . . . 22

26    Environmental Laws . . . . . . . . . . . . . . . . . . . 22

27    Signs. . . . . . . . . . . . . . . . . . . . . . . . . . 25



<PAGE>

                              LIST OF DEFINED TERMS

Defined Term                                                 Page

Additional Rent. . . . . . . . . . . . . . . . . . . . . . . . .3
Affiliate. . . . . . . . . . . . . . . . . . . . . . . . . . .110
AS-IS. . . . . . . . . . . . . . . . . . . . . . . . . . . . .G-1
Balance of Suite 500 . . . . . . . . . . . . . . . . . . . . . .1
Basic Rent . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Building . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Casualty . . . . . . . . . . . . . . . . . . . . . . . . . . .143
Commencement Date. . . . . . . . . . . . . . . . . . . . . . . .1
Construction Allowance . . . . . . . . . . . . . . . . . . . .C-2
Damage Notice. . . . . . . . . . . . . . . . . . . . . . . . . 14
Determination Notice . . . . . . . . . . . . . . . . . . . . .F-1
Event of Default . . . . . . . . . . . . . . . . . . . . . . . 15
Exercise Date. . . . . . . . . . . . . . . . . . . . . . . . .F-1
Initial Portion of Premises. . . . . . . . . . . . . . . . . . .1
Landlord . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Landlord's Mortgagee . . . . . . . . . . . . . . . . . . . . . 12
Lease. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Letter of Credit . . . . . . . . . . . . . . . . . . . . . . . .5
Loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
Market Value Rent. . . . . . . . . . . . . . . . . . . . . . .F-1
Offer Notice . . . . . . . . . . . . . . . . . . . . . . . . .G-1
Offer Space. . . . . . . . . . . . . . . . . . . . . . . . . .G-1
Operating Costs. . . . . . . . . . . . . . . . . . . . . . . . .3
Operating Costs and Tax Statement. . . . . . . . . . . . . . . .5
Parking Area . . . . . . . . . . . . . . . . . . . . . . . . .D-1
Permitted Use. . . . . . . . . . . . . . . . . . . . . . . . . .8
Premises . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Renewal Option(s). . . . . . . . . . . . . . . . . . . . . . .F-1
Renewal Term(s). . . . . . . . . . . . . . . . . . . . . . . .F-1
Rent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Security Deposit . . . . . . . . . . . . . . . . . . . . . . . .5
Taking . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Taxes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4
Tenant . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Tenant Delay Date. . . . . . . . . . . . . . . . . . . . . . .C-3
Term . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Transfer . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Work . . . . . . . . . . . . . . . . . . . . . . . . . . . . .C-1
Working Drawings . . . . . . . . . . . . . . . . . . . . . . .C-1

<PAGE>

                                 LEASE


   THIS LEASE AGREEMENT (this "Lease") is dated March 13, 1997,  between WHC-SIX
REAL ESTATE  L.P.,  a Delaware  limited  partnership  ("Landlord"),  and PALATIN
TECHNOLOGIES, INC., a Delaware corporation, (Tenant").

    1. Lease  Grant.  Subject  to the terms of this  Lease,  Landlord  initially
leases to Tenant,  and Tenant  initially leases from Landlord Suite No. 500 (the
"Premises") in the office building (the  "Building")  located at 125 May Street,
Edison, New Jersey.  Landlord and Tenant acknowledge that initially Tenant shall
be occupying only a 9,000 square foot portion ("Initial Portion of Premises") of
the  Premises,   notwithstanding  that  certain  Tenant  improvements  shall  be
constructed  by Tenant for the 1,538 square foot balance of Suite 500  ("Balance
of Suite 500")  simultaneously  with the construction of Tenant improvements for
the Initial  Portion of Premises.  The land on which the Building is located and
the  Premises  are  described  on Exhibits A. The term  "Building"  includes the
related land, driveways,  parking facilities, and similar improvements,  but for
purposes of  Operating  Expenses  (Operating  Cost and Taxes) shall be deemed to
mean the two (2)  Buildings  within  the office  complex  and the  related  land
(described  on  Exhibit  A),   driveways,   parking   facilities,   and  similar
improvements.

    2.  Term.

   (a) The term of this Lease shall be ten (10) years  commencing the earlier of
(i)  ninety-seven  (97) days following the date that the existing  tenant in the
Premises  vacates  the  Premises  or (ii)  the  date a  temporary  or  permanent
certificate  of  occupancy is issued for the Initial  Portion of Premises,  (the
"Commencement  Date") and expiring at 5:00 p.m.,  ten (10) years  following  the
Commencement Date (the "Term",  which definition shall, upon Tenant's timely and
other proper exercise of the Renewal  Option(s) (as hereinafter  defined),  also
include all renewals of the initial Term). If the  Commencement  Date is not the
first day of a calendar month, then the Term shall be extended for the number of
days between the  Commencement  Date and the first day of the  following  month.
Notwithstanding  the  foregoing,  the  ninety-seven  (97)  day  period  shall be
extended by the number of days in excess of five (5) business days, if any, that
Landlord  takes to respond to  Tenant's  request  for  approval  of the  working
drawings  submitted to Landlord by Tenant in accordance with Exhibit C (i.e., if
Landlord  takes 8 days [of which the first 5 days are business  days] to respond
to Tenant, the 97 day period is extended by 3 days).

    (b) Once the  Commencement  Date is  ascertained,  Landlord and Tenant shall
each execute a notice of the  Commencement  Date, and  thenceforth  the date set
forth in the notice shall be conclusively presumed to be the Commencement Date.

    (c) In the event the  existing  tenant in the  Premises  has not vacated the
Premises  prior to June 15, 1997,  Tenant can terminate  this Lease upon written
notice to Landlord  prior to June 20, 1997,  whereupon any Rent paid to Landlord
(including,  but not  limited  to, the  Security  Deposit)  shall be returned to
Tenant and neither party shall have any further  rights or  obligations  towards
the other.

<PAGE>

    (d) Landlord  shall not be in default  hereunder  nor liable for damages for
 any delay to, or extension of, the Commencement Date.

    3.  Rent

   (a) (i) Basic Rent.  "Basic Rent"  (herein so called)  shall be the following
amounts for the following periods of time, subject to the increase in Basic Rent
as determined in subparagraph 3(a)(ii),  which shall in no event affect the rent
schedule from and after the twenty-fifth (25th) month:

     Time Period        Anual Rent    Monthly Basic Rent
- ----------------       -----------    ------------------
 Months 1-12           $115,690.00      $ 9,640.83
        13-24           118,766.00        9,897.17
        25-36           126,456.00       10,538.00
        37-60           158,070.00       13,172.50
        61-120          200,222.00       16,685.17

    (ii) As of the earlier of (a) two (2) years following the Commencement  Date
or (b) the date  Tenant  utilizes  or  occupies  the Balance of Suite 500 in its
regular course of business  ("Total  Occupancy Date") and up to the commencement
of the 25th month of the Term (pro rated for any partial month),  the Basic Rent
for the Premises shall be increased  from and after the Total  Occupancy Date to
the rate of $126,456.00 per annum,  payable in consecutive  monthly  payments of
$10,538.00.

    (b)  Payment.  Tenant  shall  timely  pay to  Landlord  Basic  Rent  and all
additional sums to be paid by Tenant to Landlord under this Lease (collectively,
the  "Rent")  without   deduction  or  set  off  (except  as  may  be  otherwise
specifically set forth in this Lease), at Landlord's notice address provided for
in this Lease or as otherwise  specified by  Landlord.  Basic Rent,  adjusted as
herein provided,  shall be payable monthly in advance,  and shall be accompanied
by all  applicable  state and local  sales or use  taxes,  if any.  The  monthly
installment for the first month of Basic Rent shall be payable contemporaneously
with the execution of this Lease; thereafter, Basic Rent shall be payable on the
first day of each  month of the Term  beginning  on the first day of the  second
full calendar month of the Term. The monthly Basic Rent for any partial month at
the  beginning or expiration of the Term shall equal the product of 1/365 of the
annual Basic Rent in effect  during the partial  month and the number of days in
the partial month.


                                   2

<PAGE>

    (c)  Operating Expenses.

    (1)  Tenant   shall  pay  an  amount   ("Additional   Rent")  equal  to  its
   proportionate  share of  Operating  Costs.  Landlord  may collect such amount
   annually  in arrears in a lump sum,  which  shall be due within 30 days after
   Landlord  furnishes to Tenant the Operating Costs and Tax Statement  (defined
   below).  Alternatively,  Landlord  may  make a  good  faith  estimate  of the
   Additional  Rent to be due by Tenant for any calendar year or part thereof by
   thirty (30) days prior notice to Tenant during the Term, and Tenant shall pay
   to Landlord,  on the Commencement  Date and on the first day of each calendar
   month thereafter,  an amount equal to the estimated  Additional Rent for such
   calendar year or part thereof divided by the number of months  therein.  From
   time to time,  Landlord  may  estimate  and  re-estimate  in good  faith  the
   Additional  Rent to be due by Tenant and  deliver a copy of the  estimate  or
   re-estimate to Tenant.  Thereafter,  the monthly  installments  of Additional
   Rent payable by Tenant shall be appropriately adjusted in accordance with the
   estimations  so that,  by the end of the calendar  year in  question,  Tenant
   shall have paid all of the  Additional  Rent as estimated  by  Landlord.  Any
   amounts  paid based on such an  estimate  shall be subject to  adjustment  as
   herein  provided when actual  Operating Costs are available for each calendar
   year.

    (2) The term  "Operating  Costs" shall mean all  expenses and  disbursements
   (subject  to the  limitations  set  forth  below)  that  Landlord  incurs  in
   connection  with the ownership,  operation,  and maintenance of the Building,
   determined  in  accordance  with  sound  accounting  principles  consistently
   applied,  including,  but not limited to, the following  costs: (A) wages and
   salaries  (including  management  fees)  of  all  employees  engaged  in  the
   operation,  maintenance,  and  security  of the  Building,  including  taxes,
   insurance and benefits relating thereto;  (B) all supplies and materials used
   in the  operation,  maintenance,  repair,  replacement,  and  security of the
   Building;  (C) costs for  improvements  made to the Building which,  although
   capital in nature,  are expected to reduce the normal  operating costs of the
   Building,  as well as capital  improvements  made in order to comply with any
   law hereafter  promulgated by any governmental  authority,  as amortized over
   the useful  economic life of such  improvements  as determined by Landlord in
   its  reasonable  discretion;  (D) cost of all  utilities,  except the cost of
   utilities  reimbursable  to Landlord  by the  Building's  tenants  other than
   pursuant to a provision similar to this Section 3.(c; (E) insurance expenses;
   (F) repairs,  replacements,  and general maintenance of the Building; and (G)
   service  or  maintenance  contracts  with  independent  contractors  for  the
   operation,  maintenance,  repair,  replacement,  or security of the  Building
   (including,  without limitation, alarm service, window cleaning, and elevator
   maintenance).

             The  following  shall not be deemed  Operating  Costs:  (i) capital
             improvements made to the Building,  other than capital improvements
             described  in Section  3(c)(2)(C)  and  except for items  which are
             generally considered maintenance

                                   3


<PAGE>


             and repair items, such as painting of common areas,  replacement of
             carpet in elevator lobbies, and the like; (ii) repair, replacements
             and general  maintenance paid by proceeds of insurance or by Tenant
             or other  third  parties;  (iii)  interest,  amortization  or other
             payments  on loans to  Landlord;  (iv)  depreciation;  (v)  leasing
             commissions;  (vi) legal  expenses for  services,  other than those
             that benefit the Building  tenants  generally (e.g., tax disputes);
             (vii) renovating or otherwise  improving space for occupants of the
             Building or vacant space in the  Building;  (viii)  Taxes  (defined
             below),  (ix) federal  income  taxes  imposed on or measured by the
             income  of  Landlord  from  the  operation  of  the  Building;  (x)
             expenditures for repairs,  replacements or rebuilding occasioned by
             fire or other  casualty  to the  Building;  (xi)  expenditures  for
             repairs, replacements or rebuilding occasioned by any of the events
             contemplated by Section 13 of this Lease;  (xii)  expenditures  for
             costs, including advertising and promotional expenses,  incurred in
             connection  with  efforts to lease  portions of the Building and to
             procure new tenants for the Building;  (xiii)  expenditures for the
             salaries,  benefits and other  compensation  of the  employees  and
             other  personnel of the Landlord or any managing  agent who are not
             contemplated  by subsection  3(c)(2)(A);  (xiv)  expenditures to an
             affiliate  of the  Landlord  to the  extent  any  such  expenditure
             exceeds the amount  that would have been  payable in the absence of
             such affiliate  relationship;  (xv)  expenditures  for  installing,
             operating  and  maintaining  any  special  facility  in or  on  the
             Building such as an observatory,  broadcasting facility,  cafeteria
             or dining  facility or athletic,  recreational  or luncheon club if
             the respective facility shall not be available to the Tenant or any
             of its employees; (xvi) expenditures for what would otherwise be an
             Operating  Cost  which  are  reimbursed   under  any   construction
             contractors' or manufacturers' or vendors'  warranties or which are
             otherwise reimbursed to the Landlord; and (xvii) Operating Costs to
             the extent that the sum of (a) the Tenant's  proportionate share of
             Operating Costs and (b) the proportionate shares of Operating Costs
             of tenants of other leased premises in the Building exceeds 100% of
             Operating Costs.

    (3) Tenant shall also pay a  proportionate  share of the Taxes for each year
   and  partial  year  falling  within the Term,  which shall be  determined  by
   multiplying the aggregate Taxes by a fraction,  the numerator of which is the
   number of rentable  square feet in the Premises and the  denominator of which
   is the number of rentable  square feet in the Building.  Tenant shall pay its
   proportionate  share of  Taxes  in the same  manner  as  provided  above  for
   Additional  Rent with regard to Operating  Costs.  "Taxes"  shall mean taxes,
   assessments,  and  governmental  charges whether  federal,  state,  county or
   municipal,  and whether they be by taxing districts or authorities  presently
   taxing or by others,  subsequently created or otherwise,  and any other taxes
   and assessments

                                   4


<PAGE>

   attributable  to  the  Building  (or  its  operation),   excluding,  however,
   penalties and interest  thereon and federal and state taxes on income (if the
   present  method of taxation  changes so that in lieu of the whole or any part
   of any Taxes, there is levied on Landlord a capital tax directly on the rents
   received therefrom or a franchise tax, assessment,  or charge based, in whole
   or in  part,  upon  such  rents  for  the  Building,  then  all  such  taxes,
   assessments,  or charges, or the part thereof so based, shall be deemed to be
   included within the term "Taxes" for purposes hereof);

    (4) By April 1 of each calendar year, or as soon  thereafter as practicable,
   Landlord  shall  furnish to Tenant a  statement  of  Operating  Costs for the
   previous  year and of the Taxes for the previous year (the  "Operating  Costs
   and Tax  Statement").  If the Operating Costs and Tax Statement  reveals that
   Tenant paid more for Operating  Costs than the actual amount for the year for
   which such statement was prepared, or more than its actual share of Taxes for
   such year, then Landlord shall promptly  credit or reimburse  Tenant for such
   excess;  likewise,  if Tenant  paid less than the actual  Additional  Rent or
   share of Taxes due, then Tenant shall promptly pay Landlord such deficiency.

    (5) Initially,  for the purposes of calculating pro-rata Operating Costs and
   Taxes in this Section 3, the parties  stipulate that the area of the Premises
   is  9,000  rentable  square  feet  and the area of the  Building  is  105,382
   rentable  square  feet.  As of the  Total  Occupancy  Date,  the  area of the
   Premises shall be deemed to be 10,538 rentable square feet.

    4. Delinquent Payment;  Handling Charges.  All past due payments required of
Tenant  hereunder  shall bear  interest from the date due until paid at the Wall
Street Journal,  Eastern Edition,  published prime rate plus 2%;  alternatively,
Landlord  may  charge  Tenant a fee  equal to 5% of the  delinquent  payment  to
reimburse  Landlord for its cost and inconvenience  incurred as a consequence of
Tenant's delinquency.  In no event,  however,  shall the charges permitted under
this Section 4 or elsewhere in this Lease,  to the extent they are considered to
be interest under law, exceed the maximum lawful rate of interest.

    5. Security  Deposit.  Upon  execution of this Lease,  in lieu of a security
deposit in immediately available funds, Tenant shall deposit with the Landlord a
one hundred eighty-five  thousand dollars and 00/100  ($185,000.00)  irrevocable
unconditional standby letter of credit ("Letter of Credit") in the form attached
hereto as Exhibit H (subject to the right of the issuer to make  non-substantive
changes  thereto) as a security  deposit  ("Security  Deposit") for the full and
faithful  performance of Tenant's obligations in this Lease in favor of Landlord
as beneficiary drawn on a financial institution  acceptable to Landlord and with
such other terms and conditions  reasonably acceptable to Landlord requiring the
issuer  to  pay  the  sum  of  One  Hundred  Eighty-Five   Thousand  and  00/100
($185,000.00) Dollars (or such reduced amount limited as hereinafter  permitted)
to Landlord upon presentation to the issuer of the letter of credit and a letter
on Landlord's letterhead stating that an Event of Default by Tenant has occurred
under this Lease and such other  customary and  reasonable  requirements  of the
issuer but without requiring  further evidence of default.  The Letter of Credit
shall be for a minimum of one (1) year

                                   5

<PAGE>


maturity and renewed on an annual basis (except as  hereinafter  permitted to be
reduced  and/or  terminated)  during the Term,  as the same may be extended and,
provided an Event of Default by Tenant has not occurred under this Lease, Tenant
may reduce the amount of the Letter of Credit by $74,000.00 at the expiration of
twenty-four (24) months from the Commencement Date and by additional  amounts of
$37,000.00 at the expiration of thirty-six (36), forty-eight (48) and sixty (60)
months from the  Commencement  Date, such that no Security  Deposit shall remain
from and after the  expiration  of the fifth (5th) lease year.  Failure to renew
the Letter of Credit  (unless  expressly  permitted to the  contrary  herein) at
least thirty (30) days prior to the expiration of any lease year shall be deemed
a material Event of Default under this Lease entitling Landlord to draw upon the
Letter of Credit and retain  the amount so drawn as a Security  Deposit.  In the
event of any dispute  between  Landlord  and Tenant with  respect to an Event of
Default and the Letter of Credit is drawn upon,  the funds so received  shall be
held by Landlord in a segregated  interest-bearing  account  (interest to follow
the principal) pending resolution of the dispute. The Security Deposit is not an
advance  payment of Rent or a measure  or limit of  Landlord's  damages  upon an
Event of Default  (defined in Section 16).  Landlord  may, from time to time and
without prejudice to any other remedy, use all or a part of the Security Deposit
to perform any obligation Tenant fails to perform hereunder.  The portion of the
Letter of Credit  proceeds  received  by  Landlord  and not  utilized  to cure a
default shall be deemed a Cash Security Deposit.  Following any such application
of the Security  Deposit,  Tenant shall  deposit with Landlord in cash on demand
the amount so applied in order to restore the  Security  Deposit to its original
amount.  Provided that Tenant has performed  all of its  obligations  hereunder,
Landlord  shall,  within the  earlier of (i) the  expiration  of the fifth (5th)
lease year, or (ii) 30 days after the Term ends, return to Tenant the portion of
the Security Deposit which was not applied to satisfy Tenant's obligations.  The
Security  Deposit,  letter of  credit  proceeds  or other  cash  payment  may be
commingled  with other  funds,  and no  interest  (other  than in the event of a
dispute  as  provided  in this  Article)  shall  be paid  thereon.  If  Landlord
transfers  its interest in the Premises and the  transferee  assumes  Landlord's
obligations  under this Lease in writing,  then  Landlord  shall assign any cash
portion of the  Security  Deposit to the  transferee  and Tenant  shall  issue a
substitute  Letter  of  Credit  to  the  transferee   simultaneously   with  the
cancellation of the existing Letter of Credit with all transfer costs associated
therewith  being borne by Tenant and Landlord  thereafter  shall have no further
liability  for the  return of the  Security  Deposit.  A copy of the  assumption
agreement shall be provided to Tenant in writing.

    6.  Landlord's Obligations

    (a) Services.  Landlord shall furnish to Tenant (1) water at those points of
supply  provided  for  general  use of tenants of the  Building;  (2) heated and
refrigerated air conditioning as appropriate,  at such  temperatures and in such
amounts  as  are  standard  for  comparable  buildings  in the  vicinity  of the
Building;  (3)  electrical  current  at all  times for  equipment  that does not
require more than 220 volts and whose  electrical  energy  consumption  does not
exceed normal combined office and laboratory  usage;  (4) a dumpster  located at
the Building for office  garbage and trash and a hauling  service to empty same;
(5) sewage  disposal for the  Building;  (6) snow and ice  clearance  from,  and
sweeping  of,  the  Parking  Area and  access  roads and walks  relating  to the
Building; (7) such maintenance and repair of the Building and its electrical,
                                   6

<PAGE>


plumbing,  HVAC, safety and other mechanical  systems and other  improvements at
the Building as is  customarily  provided for  comparable  office and laboratory
buildings  within a 10-mile  radius from the  Building;  and (8) all those items
which are  contemplated  as Operating Costs under section 3(c)(2) of this Lease.
Landlord  shall  maintain the common areas of the  Building in  reasonably  good
order and  condition,  except for damage  caused by  Tenant,  or its  employees,
agents or invitees. Tenant shall pay, as Additional Rent, the total electricity,
water and gas charges for the Premises at the supplying utility's rates therefor
as determined pursuant to separate submeters for the Premises.  Tenant shall pay
for all light  bulbs  (including  exit sign  light  bulbs) and  ballasts  in the
Premises.

    (b) Excess Utility Use. Landlord shall not be required to furnish electrical
current for equipment that requires more than 220 volts or other equipment whose
electrical  energy  consumption  exceeds normal office and laboratory  usage. If
Tenant's  requirements for or consumption of electricity  exceed the electricity
to be provided by Landlord as  described in Section  6(a),  Landlord  shall,  at
Tenant's  expense,  make  reasonable  efforts to supply such service through the
then-existing  feeders and risers  serving the  Building and the  Premises,  and
Tenant  shall pay to  Landlord  the cost of such  service  within ten days after
Landlord has delivered to Tenant an invoice therefor. Landlord may determine the
amount  of  such  additional   consumption  and  potential  consumption  by  any
verifiable  method,  including  installation of a separate meter in the Premises
installed,  maintained,  and read by Landlord, at Tenant's expense. Tenant shall
not install any  electrical  equipment  requiring  special  wiring or  requiring
voltage in excess of 220 volts or otherwise  exceeding  Building capacity unless
approved in advance by Landlord.  The use of  electricity  in the Premises shall
not exceed  the  capacity  of  existing  feeders  and risers to or wiring in the
Premises.  Notwithstanding  any  provisions in this Lease to the  contrary,  any
risers or wiring required to meet Tenant's excess electrical requirements shall,
upon Tenant's written request,  be installed by Landlord,  at Tenant's cost, if,
in Landlord's  judgment,  the same are  necessary and shall not cause  permanent
damage to the Building or the Premises, cause or create a dangerous or hazardous
condition,  entail excessive or unreasonable alterations,  repairs, or expenses,
or  interfere  with or disturb  other  tenants of the  Building.  If Tenant uses
machines or equipment in the Premises  which  materially  adversely  affects the
temperature  otherwise  maintained by the air  conditioning  system or otherwise
overload any utility,  Landlord, after consulting with Tenant for the purpose of
cooperation  to develop a  reasonable  solution,  may install  supplemental  air
conditioning units or other  supplemental  equipment in the Premises designed to
remedy the adverse effect or overload, and the cost thereof,  including the cost
of installation,  operation,  use, and  maintenance,  shall be paid by Tenant to
Landlord  within  ten days after  Landlord  has  delivered  to Tenant an invoice
therefor. Tenant acknowledges that, currently, current for 110 volts is supplied
to the  Premises  and that all  costs  associated  in  supplying  the 220  volts
required by Tenant shall be borne by Tenant.

    (c)  Restoration  of  Services;  Abatement.  Landlord  shall use  reasonable
efforts to restore any service required of it that becomes unavailable; however,
such  unavailability  shall not render  Landlord  liable for any damages  caused
thereby,  be a  constructive  eviction  of  Tenant,  constitute  a breach of any
implied warranty, or, except as provided in the next sentence,

                                   7

<PAGE>


entitle Tenant to any abatement of Tenant's obligations hereunder.  If, however,
Tenant is  prevented  from  using  the  Premises  for more  than 15  consecutive
business days because of the  unavailability of any such services referred to in
Section  6(a)(1)-(7)  or Tenant is denied  access to the Building as a result of
acts within Landlord's  control for more than fifteen (15) consecutive  business
days,  then Tenant shall,  as its  exclusive  remedy be entitled to a reasonable
abatement  of Rent for each  consecutive  day (after  such 15-day  period)  that
Tenant is so prevented from using the Premises. In no event, however,  shall the
abatement apply to Section 6(a)(8) items.

    7.  Improvements; Alterations; Repairs; Maintenance.

    (a)  Improvements;  Alterations.  Improvements  to  the  Premises  shall  be
installed at Tenant's  expense only in accordance with plans and  specifications
which have been previously submitted to and approved in writing by Landlord.  No
alterations  or physical  additions  in or to the  Premises  may be made without
Landlord's  prior written  consent,  which shall not be  unreasonably  withheld,
delayed or  conditioned;  however,  Landlord  may  withhold  its  consent to any
alteration or addition that would adversely  affect the Building's  structure or
adversely affect its HVAC, plumbing,  electrical,  or mechanical systems. Tenant
shall  not paint or  install  lighting  or  decorations,  signs,  window or door
lettering, or advertising media of any type on or about the Premises without the
prior written  consent of Landlord,  which shall not be  unreasonably  withheld,
delayed or conditioned;  however,  Landlord may withhold its consent to any such
painting or  installation  which would affect the  appearance of the exterior of
the Building or of any common areas of the Building. All alterations, additions,
or improvements made in or upon the Premises shall, at Landlord's option, either
be removed by Tenant  prior to the end of the Term (and Tenant  shall repair all
damage caused  thereby),  or shall remain on the Premises at the end of the Term
without compensation to Tenant.  Whenever Tenant applies to Landlord for consent
to a proposed  alteration,  addition or  improvement  that includes items in the
nature of  fixtures  to real  property,  in  connection  with any  consent  that
Landlord might give,  Landlord  shall advise Tenant by notice  whether  Landlord
will require  Tenant to remove or to leave behind such items upon  expiration of
the Term. All alterations,  additions,  and  improvements  shall be constructed,
maintained,  and used by Tenant, at its risk and expense, in accordance with all
applicable laws;  Landlord's  approval of the plans and specifications  therefor
shall not be a representation by Landlord that such alterations,  additions,  or
improvements comply with any law.

    (b) Repairs;  Maintenance.  Tenant  shall  maintain the Premises in a clean,
safe, and operable condition,  and shall not permit or allow to remain any waste
or damage to any portion of the Premises.  Subject to the  provisions of Section
14,  Tenant  shall  repair or  replace,  subject  to  Landlord's  direction  and
supervision,  any damage to the Building caused by Tenant, Tenant's transferees,
or their respective agents,  contractors,  or invitees.  If Tenant fails to make
such repairs or replacements within 30 days after the occurrence of such damage,
then  Landlord  may make the same at Tenant's  cost.  If any such damage  occurs
outside  of the  Premises,  then  Landlord  may elect to repair  such  damage at
Tenant's expense,  rather than having Tenant repair such damage. The cost of all
repair or replacement work performed by Landlord under this


                                   8

<PAGE>


Section 7 shall be paid by Tenant to Landlord within ten days after Landlord has
invoiced Tenant therefor.

    (c)  Performance  of Work.  All work  described  in this  Section 7 shall be
performed  only by Landlord or by  contractors  and  subcontractors  approved in
writing  by   Landlord.   Tenant  shall  cause  all  of  its   contractors   and
subcontractors to procure and maintain  insurance coverage naming Landlord as an
additional insured against such risks, in such amounts,  and with such companies
as  Landlord  may  reasonably  require.  All such  work  shall be  performed  in
accordance with all legal  requirements and in a good and workmanlike  manner so
as not to damage the Premises, the Building, or the components thereof.

    (d) Construction Liens. Tenant shall not permit any construction liens to be
filed  against the Premises or the Building  for any work  performed,  materials
furnished, or obligation incurred by or at the request of Tenant by a contractor
under contract to Tenant or its  subcontractors or suppliers of materials to the
contractor or subcontractor. If such a lien is filed pursuant to work contracted
by Tenant,  then Tenant  shall,  within ten days after  Landlord  has  delivered
notice of the filing  thereof  to  Tenant,  either pay the amount of the lien or
diligently  contest  such lien and  deliver to  Landlord  or to the Clerk of the
Court with  jurisdiction a bond or other  security  reasonably  satisfactory  to
Landlord or in compliance with the requirements of the construction  lien law in
order to have such  construction  lien  released or bonded.  If Tenant  fails to
timely take either such action,  then  Landlord may pay the lien claim,  and any
amounts so paid,  including  expenses and  interest,  shall be paid by Tenant to
Landlord within ten days after Landlord has invoiced Tenant therefor.

    (e) To the  extent  Exhibit  C of this  Lease may be  inconsistent  with any
requirement of this Section 7 of the Lease  regarding the Work  contemplated  by
Exhibit C, the provisions of Exhibit C shall control.

    8. Use.  Tenant  shall  continuously  occupy and use the  Premises  only for
general office and  laboratory use (the " Permitted  Use") and shall comply with
all laws, orders, rules, and regulations relating to the use, condition,  access
to, and occupancy of the Premises  (including,  but not limited to, the storage,
handling and experimentation of animals).  Tenant acknowledges that the research
on animals  shall be limited to rodents  and that there shall be (a) no breeding
of animals,  nor (b) housing of animals in excess of  twenty-four  (24) hours at
the Premises.  Tenant shall not permit the  Premises,  or any part thereof to be
used in any manner which would in any way discharge  objectionable fumes, vapors
or odors  into the  Building's  air  conditioning  system  or flues or vents not
designated to receive them.  The Premises shall not be used for any use which is
disreputable,  creates  extraordinary  fire hazards,  or results in an increased
rate of  insurance on the  Building or its  contents,  or for the storage of any
hazardous  materials or substances,  which hazardous materials or substances are
not lawfully utilized in connection with Tenant's  Permitted Use. If, because of
Tenant's acts, the rate of insurance on the Building or its contents  increases,
then such acts shall be an Event of Default,  Tenant  shall pay to Landlord  the
amount of such  increase on demand,  and  acceptance  of such payment  shall not
waive any of Landlord's other rights. Tenant shall conduct


                                   9

<PAGE>


its business and control its agents, employees, and invitees in such a manner as
not to create any  nuisance  or  unreasonably  interfere  with other  tenants or
Landlord in its management of the Building.


    9.  Assignment and Subletting

    (a) Transfers;  Consent. Tenant shall not, without the prior written consent
of  Landlord,  (1) assign,  transfer,  or  encumber  this Lease or any estate or
interest  herein,  whether directly or by operation of law (except an assignment
to an Affiliate (as hereinafter  defined) of Tenant), (2) if Tenant is an entity
other than a corporation whose stock is publicly traded, permit any other entity
to become Tenant hereunder by merger,  consolidation,  or other  reorganization,
(3) if Tenant is an entity  other than a  corporation  whose  stock is  publicly
traded,  permit the transfer of an ownership  interest in Tenant so as to result
in a change in the  current  control  of Tenant,  (4) sublet any  portion of the
Premises (except to an Affiliate of Tenant), (5) grant any license,  concession,
or other  right of  occupancy  of any  portion  of the  Premises  (except  to an
Affiliate of Tenant), or (6) permit the use of the Premises by any parties other
than  Tenant or an  Affiliate  of Tenant  (any of the  events  listed in Section
9.(a)(1)  through  9.(a)(6) being a "Transfer").  If Tenant requests  Landlord's
consent  to a  Transfer,  then  Tenant  shall  provide  Landlord  with a written
description of all terms and conditions of the proposed Transfer,  copies of the
proposed  documentation,  and  the  following  information  about  the  proposed
transferee:  name and address;  reasonably  satisfactory  information  about its
business  and business  history;  its  proposed  use of the  Premises;  banking,
financial,  and other credit information;  and general references  sufficient to
enable  Landlord to determine the proposed  transferee's  credit  worthiness and
character.  Landlord  shall not  unreasonably  withhold,  delay or condition its
consent to any  assignment  or  subletting  of the  Premises,  provided that the
proposed  transferee  (A) is credit  worthy,  (B) has a good  reputation  in the
business  community,  and (C) is not  another  occupant  of the  Building if the
Landlord  then  has  space  available  in the  Building  that  meets  the  other
occupant's requirements for additional space;  otherwise,  Landlord may withhold
its  consent  in its sole  discretion  by notice to  Tenant.  Concurrently  with
Tenant's  notice of any request for consent to a Transfer,  Tenant  shall pay to
Landlord  a fee of $500.00  to defray  Landlord's  expenses  in  reviewing  such
request,  and Tenant shall also reimburse Landlord  immediately upon request for
its reasonable  attorneys' fees, if any, incurred in connection with considering
and/or  performing  any legal  services  regarding  any request for consent to a
Transfer.  If  Landlord  consents  to a  proposed  Transfer,  then the  proposed
transferee  shall deliver to Landlord a written  agreement  whereby it expressly
assumes the Tenant's obligations hereunder; however, any transferee of less than
all of the space in the Premises shall be liable only for obligations under this
Lease that are properly  allocable to the space  subject to the Transfer for the
period of the  Transfer.  Landlord's  consent  to a Transfer  shall not  release
Tenant  from its  obligations  under  this  Lease,  but  rather  Tenant  and its
transferee shall be jointly and severally liable therefor. Landlord's consent to
any Transfer shall not waive Landlord's  rights as to any subsequent  Transfers.
If an Event of Default  contemplated  by  Subsection  16(a) of this Lease occurs
while the Premises or any part thereof are subject to a

                                  10

<PAGE>


Transfer, then Landlord, in addition to its other remedies, may collect directly
from such  transferee  all rents  becoming  due to Tenant  and apply  such rents
against  Rent.  Tenant  authorizes  its  transferees  to make  payments  of rent
directly to Landlord upon receipt of notice from Landlord to do so.

    (b)  Cancellation.  Landlord  may by notice to Tenant,  within 30 days after
submission of Tenant's  written request for Landlord's  consent to an assignment
or  subletting,  cancel  this Lease  (unless  Tenant  withdraws  its  request to
Landlord  in  writing  and  within  two  (2)  business  days of its  receipt  of
Landlord's  notice) as to the portion of the  Premises  proposed to be sublet or
assigned as of the date the proposed  Transfer is to be  effective.  If Landlord
cancels  this Lease as to any  portion of the  Premises,  then this Lease  shall
cease for such portion of the Premises and Tenant shall pay to Landlord all Rent
accrued  through the  cancellation  date relating to the portion of the Premises
covered by the proposed Transfer. Thereafter, Landlord may lease such portion of
the  Premises  to  the  prospective  transferee  (or  to any  other  person)  in
compliance with all applicable building, fire and use codes without liability to
Tenant.

    (c) Additional Compensation.  Tenant shall pay to Landlord, immediately upon
receipt  thereof,  fifty  percent  (50%) of the  excess of (1) all  compensation
received by Tenant for a Transfer less the costs  reasonably  incurred by Tenant
with  unaffiliated  third  parties  in  connection  with  such  Transfer  (i.e.,
brokerage  commissions,  tenant  finish  work,  and the like)  over (2) the Rent
allocable to the portion of the Premises covered thereby.

   (d) The term  "Affiliate"  shall  mean any  person  or  entity,  directly  or
indirectly, controlling, controlled by, or under common control
  with Tenant.

    10.  Insurance; Waivers; Subrogation; Indemnity

    (a)  Insurance.  Tenant shall  maintain  throughout  the Term the  following
insurance policies:  (1) comprehensive general liability insurance in amounts of
not less than a combined  single limit of  $2,000,000  or such other  amounts as
Landlord may from time to time reasonably  require as is customary for buildings
of similar size, use and nature,  insuring Tenant,  Landlord,  Landlord's agents
and their respective  affiliates against all liability for injury to or death of
a person or persons or damage to property  arising from the use and occupancy of
the  Premises,  (2) insurance  covering the full value of Tenant's  property and
improvements, and other property (including property of others) in the Premises,
(3)  contractual  liability  insurance  sufficient to cover  Tenant's  indemnity
obligations  hereunder,  and (4) worker's compensation  insurance,  containing a
waiver of subrogation  endorsement  acceptable to Landlord.  Tenant's  insurance
shall  provide  primary  coverage to Landlord when any policy issued to Landlord
provides  duplicate or similar  coverage,  and in such  circumstance  Landlord's
policy will be excess over  Tenant's  policy.  Tenant shall  furnish to Landlord
certificates of such insurance and such other evidence  satisfactory to Landlord
of the maintenance of all insurance  coverages  required  hereunder,  and Tenant
shall  obtain a written  obligation  on the part of each  insurance  company  to
notify Landlord at least 30 days before cancellation or a material change of any
such  insurance  policies.  All such  insurance  policies  shall be in form, and
issued by companies, reasonably

                                  11

<PAGE>


satisfactory to Landlord.  The term "affiliate" shall mean any person or entity,
directly or indirectly, controlling, controlled by, or under common control with
the party in question.

    (b) Waiver of Negligence;  No  Subrogation.  Landlord and Tenant each waives
any claim it might  have  against  the  other for any  injury to or death of any
person or persons or damage to or theft,  destruction,  loss,  or loss of use of
any property (a " Loss"),  to the extent the same is insured  against  under any
insurance policy that covers the Building, the Premises,  Landlord's or Tenant's
fixtures,  personal property,  leasehold  improvements,  or business, or, in the
case of  Tenant's  waiver,  is required  to be insured  against  under the terms
hereof,  regardless  of whether the  negligence  of the other party  caused such
loss;  however,  Landlord's  waiver shall not include any deductible  amounts on
insurance policies carried by Landlord not to exceed $10,000 on any policy. Each
party  shall cause its  insurance  carrier to endorse  all  applicable  policies
waiving the carrier's rights of recovery under  subrogation or otherwise against
the other party.

    (c) Indemnity.  Subject to Section 10.(b),  Tenant shall defend,  indemnify,
and hold harmless Landlord and its  representatives  and agents from and against
all claims, demands,  liabilities,  causes of action, suits, judgments, damages,
and expenses (including  attorneys' fees) arising from (i) any Loss arising from
any  occurrence  on the  Premises  or  (ii)  Tenant's  failure  to  perform  its
obligations  under this Lease.  This indemnity  provision shall exclude the acts
and/or omissions of Landlord, its agents,  employees and contractors,  and shall
survive  termination or expiration of this Lease. If any proceeding is filed for
which indemnity is required hereunder,  Tenant agrees, upon request therefor, to
defend  the  indemnified  party in such  proceeding  at its sole cost  utilizing
counsel satisfactory to the indemnified party.

    11.  Subordination Attornment; Notice to Landlord's Mortgagee

    (a)   Subordination.   Provided  the  Subordination,   Non-Disturbance   and
Attornment  Agreements  and  recognition  agreements are delivered to Tenant for
execution  in the  forms  as  required  in this  subparagraph,  within  five (5)
business  days of receipt of same,  Tenant  agrees to execute,  acknowledge  and
deliver  same to  Landlord  and/or any other  party  directed  by  Landlord  for
execution by all required parties and upon receipt by Tenant of a fully executed
duplicate  original of said document(s),  this Lease shall be subordinate to the
deed of trust,  mortgage,  or other  security  instrument,  or any ground lease,
master lease,  or primary lease,  referred to in the  applicable  Subordination,
Non-Disturbance  and  Attornment  Agreement  and/or  recognition   agreement  so
executed and  delivered  (the  mortgagee  under any such  mortgage or the lessor
under any such lease is referred to herein as a  "Landlord's  Mortgagee").  With
respect  to the  existing  mortgagee,  Tenant  shall  execute  and  deliver  the
Subordination, Non-Disturbance and Attornment Agreement and Estoppel Certificate
annexed hereto as Exhibit E. Landlord agrees to obtain for the benefit of Tenant
a   Subordination,   Non-Disturbance   and  Attornment   Agreement  from  future
mortgagees,  on forms  substantially  as set forth in Exhibit E (which form must
provide the same  benefits  to all  parties as provided  for in Exhibit E) which
Tenant agrees to execute. Landlord shall obtain

                                  12

<PAGE>


recognition  agreements  for the  benefit  of  Tenant,  which  Tenant  agrees to
execute,  with respect to any ground  lease,  master  lease or primary  lease on
forms reasonably acceptable to Landlord,  Tenant and the applicable lessor which
Tenant  agrees to execute.  Any  Landlord's  Mortgagee  may elect,  at any time,
unilaterally,  to make this Lease  superior to its mortgage,  ground  lease,  or
other interest in the Premises by so notifying Tenant in writing.

    (b)  In  the  event  that  Landlord   submits  to  Tenant  a  Subordination,
Non-Disturbance  and  Attornment  Agreement  and/or  recognition  agreement,  as
applicable,  complying with the provisions of subparagraph  (a) and Tenant fails
to execute,  acknowledge  and deliver  same  within  five (5)  business  days of
receipt  thereof,  then subject to mortgagee's  election  rights provided in the
last sentence of  subparagraph  (a), this Lease shall be subordinate to the deed
of trust,  mortgage,  or other security instrument,  or any ground lease, master
lease, or primary lease referred to in the  Subordination,  Non-Disturbance  and
Attornment  Agreement and/or recognition  agreement  delivered to Tenant without
further action on the part of any party.

     (c) Attornment.  Tenant shall attorn to any party  succeeding to Landlord's
interest in the  Premises,  whether by  purchase,  foreclosure,  deed in lieu of
foreclosure,  power of sale,  termination  of  lease,  or  otherwise,  upon such
party's request, and shall execute such agreements confirming such attornment as
such party may reasonably request.

    (d) Notice to  Landlord's  Mortgagee.  Tenant  shall not seek to enforce any
remedy it may have for any  default on the part of the  Landlord  without  first
giving written notice by certified mail,  return receipt  requested,  specifying
the default in reasonable detail, to any Landlord's  Mortgagee whose address has
been given to Tenant,  and  affording  such  Landlord's  Mortgagee a  reasonable
opportunity to perform Landlord's obligations hereunder.


    12.  Rules  and  Regulations.   Tenant  shall  comply  with  the  rules  and
regulations  of the Building  which are attached  hereto as Exhibit B.  Landlord
may, from time to time, change such rules and regulations for the safety,  care,
or  cleanliness  of the  Building  and related  facilities,  provided  that such
changes are applicable to all tenants of the Building and will not  unreasonably
interfere  with Tenant's use of the Premises and are not  inconsistent  with the
other  provisions of this Lease.  Tenant shall be responsible for the compliance
with such rules and regulations by its employees, agents, and invitees.

    13.  Condemnation.

    (a) Total Taking.  If the entire  Building or Premises are taken by right of
eminent  domain or  conveyed  in lieu  thereof (a  "Taking"),  this Lease  shall
terminate as of the date of the Taking.


                                  13

<PAGE>


    (b) Partial Taking - Tenant's  Rights.  If any part of the Building  becomes
subject to a Taking and such Taking will  prevent  Tenant  from  conducting  its
business in the Premises in a manner  reasonably  comparable  to that  conducted
immediately  before such  Taking for a period of more than 90 days,  then Tenant
may terminate  this Lease as of the date of such Taking by giving written notice
to Landlord within 30 days after the Taking, and Rent shall be apportioned as of
the date of such  Taking.  If Tenant does not  terminate  this Lease,  then Rent
shall be  abated  on a  reasonable  basis  as to that  portion  of the  Premises
rendered untenantable by the Taking.

    (c) Partial Taking - Landlord's  Rights. If any material  portion,  but less
than all,  of the  Building  becomes  subject  to a Taking,  or if  Landlord  is
required  to pay any of the  proceeds  received  for a  Taking  to a  Landlord's
Mortgagee,  then Landlord may terminate this Lease by delivering  written notice
thereof  to  Tenant  within  30 days  after  such  Taking,  and  Rent  shall  be
apportioned  as of the date of such  Taking.  If Landlord  does not so terminate
this Lease,  then this Lease will  continue,  but if any portion of the Premises
has been taken,  Rent shall  abate as  provided in the last  sentence of Section
13.(b).

    (d) Award.  If any Taking  occurs,  then  Landlord  shall receive the entire
award or other compensation for the land on which the Building is situated,  the
Building, and other improvements taken, and Tenant may separately pursue a claim
(to the extent it will not reduce  Landlord's  award)  against the condemnor for
the value of Tenant's personal property which Tenant is entitled to remove under
this Lease, moving costs, loss of business, and other claims it may have.

    14.  Fire or Other Casualty

    (a) Repair Estimate.  If the Premises or the Building are damaged by fire or
other  casualty  (a  "Casualty"),  Landlord  shall,  within 45 days  after  such
Casualty,  deliver to Tenant a good faith estimate (the "Damage  Notice") of the
time needed to repair the damage caused by such Casualty.

    (b)  Landlord's  and  Tenant's  Rights.  If a 50% or greater  portion of the
Premises or a material  portion of the Building is damaged by Casualty such that
Tenant is  prevented  from  conducting  its business in the Premises in a manner
reasonably  comparable to that  conducted  immediately  before such Casualty and
Landlord  estimates that the damage caused thereby cannot be repaired within 120
days  after  the  Casualty  or  in  the  event  Landlord  commences  repairs  as
hereinafter set forth and does not  substantially  complete same within 180 days
from the Casualty,  then Tenant may terminate  this Lease by delivering  written
notice to Landlord of its election to terminate  within 30 days after the Damage
Notice has been delivered to Tenant. If Tenant does not so timely terminate this
Lease,  then  (subject to Sections  14.(c) and (d))  Landlord  shall  repair the
Building or the Premises,  as the case may be, as provided  below,  and Rent for
the portion of the Premises rendered  untenantable by the damage shall be abated
from the date of damage  until the  earlier of (i) four (4) months from the date
of the shell of the Premises being completed by Landlord and electric brought to
the Premises by Landlord; or (ii) the date a

                                  14

<PAGE>


Certificate of Occupancy is issued with respect to the Premises after Landlord's
and Tenant's  repairs have been completed (or the repair is completed and Tenant
is permitted to occupy the Premises if no Certificate of Occupancy is required).

    (c)  Landlord's  Rights.  If a Casualty  damages a  material  portion of the
Building,  and Landlord  makes a good faith  determination  that  restoring  the
Premises would be uneconomical, then Landlord may terminate this Lease by giving
written  notice of its  election  to  terminate  within 30 days after the Damage
Notice has been delivered to Tenant, and Basic Rent and Additional Rent shall be
abated as of the date of the Casualty.

    (d) Repair  Obligation.  If neither  party  elects to  terminate  this Lease
following a Casualty,  then Landlord shall,  within a reasonable time after such
Casualty,  begin to repair the  Building and the shell of the Premises and shall
proceed  with  reasonable  diligence  to restore the  Building  and shell of the
Premises to substantially the same condition as they existed  immediately before
such Casualty;  however, Landlord shall not be required to repair or replace any
of the furniture,  equipment,  fixtures,  and other  improvements which may have
been placed by, or at the request of,  Tenant (it being  acknowledged  by Tenant
that it shall insure and replace all improvements in the Premises other than the
shell of the Premises) or other  occupants in the Building or the Premises,  and
Landlord's obligation to repair or restore the Building or shell of the Premises
shall be limited to the extent of the  insurance  proceeds  notwithstanding  the
application  of any  portion  of the  proceeds  by a lender  towards  Landlord's
indebtedness  to the lender.  As used herein,  the term "shell of the  Premises"
shall mean  sheetrocked  exterior  walls and a hung  ceiling with respect to the
Premises.

    15. Taxes.  Tenant shall be liable for any personal property taxes levied or
assessed against  personal  property,  furniture,  or trade fixtures (not in the
nature of fixtures to real  property)  placed by Tenant in the Premises.  If any
personal  property  taxes for which  Tenant is  liable  are  levied or  assessed
against Landlord or Landlord's  property and Landlord elects to pay the same, or
if the assessed  value of Landlord's  property is increased by inclusion of such
personal  property,  furniture or fixtures and Landlord  elects to pay the taxes
based on such increase, then Tenant shall pay to Landlord, upon demand, the part
of such personal  property taxes for which Tenant is primarily liable hereunder;
however,  Landlord shall not pay such amount if Tenant notifies Landlord that it
will  contest the  validity or amount of such  personal  property  taxes  before
Landlord  makes such  payment,  and  thereafter  diligently  proceeds  with such
contest in accordance  with law and if the  non-payment  thereof does not pose a
threat of loss or seizure of the Building or interest of Landlord therein.

    16. Events of Default.  Each of the following occurrences shall be an "Event
of Default":


                                  15

<PAGE>


    (a)  Tenant's  failure  to pay Rent  within  five days  after  Landlord  has
delivered  notice to Tenant that the same is due;  however,  an Event of Default
shall occur  hereunder  without any obligation of Landlord to give any notice if
Landlord has given Tenant  written notice under this Section 16.(a) on more than
two (2) occasions  during the twelve (12) month interval  immediately  preceding
such failure by Tenant;

    (b) Tenant's failure to perform, comply with, or observe any other agreement
or obligation of Tenant under this Lease and the continuance of such failure for
a period of more than 30 days after  Landlord has  delivered  to Tenant  written
notice thereof; and

    (c) The filing of a petition by or against  Tenant (the term "Tenant"  shall
include,  for the purpose of this Section 16.(c),  any guarantor of the Tenant's
obligations hereunder) (1) in any bankruptcy or other insolvency proceeding; (2)
seeking any relief  under any state or federal  debtor  relief law;  (3) for the
appointment of a liquidator or receiver for all or substantially all of Tenant's
property or for Tenant's  interest in this Lease; or (4) for the  reorganization
or modification of Tenant's capital  structure;  however,  if such a petition is
filed against  Tenant,  then such filing shall not be an Event of Default unless
Tenant fails to have the proceedings initiated by such petition dismissed within
90 days after the filing thereof.

    17.  Remedies.  Upon any Event of Default,  Landlord may, in addition to all
other rights and remedies afforded Landlord hereunder or by law or equity,  take
any of the following actions:

    (a) Terminate this Lease by giving Tenant written notice  thereof,  in which
event Tenant  shall pay to Landlord  the sum of (1) all Rent  accrued  hereunder
through the date of termination,  (2) all amounts due under Section 18.(a),  and
(3) an amount  equal to the total Rent that Tenant  would have been  required to
pay for the  remainder  of the Term  discounted  to its  present  value  using a
discount rate of four (4%) per annum.

    (b) Terminate  Tenant's  right to possess the Premises  without  terminating
this Lease by giving  written  notice  thereof to Tenant,  in which event Tenant
shall pay to Landlord (1) all Rent and other  amounts  accrued  hereunder to the
date of termination  of possession,  (2) all amounts due from time to time under
Section  18.(a),  and (3) all Rent and other net sums  required  hereunder to be
paid by Tenant  during the  remainder  of the Term,  diminished  by any net sums
thereafter  received by Landlord  through  reletting  the  Premises  during such
period,  after  deducting  all costs  incurred  by  Landlord  in  reletting  the
Premises.  Landlord shall use  reasonable  efforts to relet the Premises on such
terms as  Landlord  in its  sole  discretion  may  determine  (including  a term
different from the Term, rental concessions, and alterations to, and improvement
of,  the  Premises);  however,  Landlord  shall  not be  obligated  to relet the
Premises  before leasing other  portions of the Building.  Landlord shall not be
liable for, nor shall Tenant's  obligations  hereunder be diminished because of,
Landlord's  failure  to  relet  the  Premises  or to  collect  rent due for such
reletting.  Tenant  shall not be  entitled  to the  excess of any  consideration
obtained by reletting  over the Rent due  hereunder.  Reentry by Landlord in the
Premises shall not affect Tenant's obligations hereunder for

                                  16

<PAGE>


the unexpired  Term;  rather,  Landlord may, from time to time,  bring an action
against  Tenant to collect  amounts  due by Tenant,  without  the  necessity  of
Landlord's  waiting until the expiration of the Term.  Unless Landlord  delivers
written notice to Tenant expressly stating that it has elected to terminate this
Lease,  all actions taken by Landlord to  dispossess or exclude  Tenant from the
Premises  shall be deemed to be taken  under this  Section  17.(b).  If Landlord
elects  to  proceed  under  this  Section  17.(b),  it may at any time  elect to
terminate this Lease under Section 17.(a); or

    (c)  Additionally,  without notice,  if permitted by law, Landlord may alter
locks or other  security  devices at the  Premises  to deprive  Tenant of access
thereto,  and  Landlord  shall not be  required to provide a new key or right of
access to Tenant.

   Any and all remedies set forth in this Lease: (i) shall be in addition to any
and all other  remedies  Landlord  may have at law or in  equity;  (ii) shall be
cumulative;  and (iii) may be pursued  successively  or concurrently as Landlord
may  elect.  The  exercise  of any  remedy  by  Landlord  shall not be deemed an
election of remedies or preclude  Landlord from exercising any other remedies in
the future.  Notwithstanding  the  foregoing,  Landlord  shall only  recover its
damages allowed hereunder once.

    18.  Payment by Tenant; Non-Waiver

    (a)  Payment  by  Tenant.  Upon any Event of  Default,  Tenant  shall pay to
Landlord all costs  incurred by Landlord  (including  court costs and reasonable
attorneys' fees and expenses) in (1) obtaining  possession of the Premises,  (2)
removing and storing Tenant's or any other occupant's  property,  (3) repairing,
restoring,   altering,  remodeling,  or  otherwise  putting  the  Premises  into
condition  acceptable  to a new  tenant,  (4)  reletting  all or any part of the
Premises (including brokerage commissions, cost of tenant finish work, and other
costs incidental to such reletting),  (5) performing Tenant's  obligations which
Tenant  failed to  perform,  and (6)  enforcing,  or advising  Landlord  of, its
rights, remedies, and recourses arising out of the Event of Default. To the full
extent permitted by law,  Landlord and Tenant agree the federal and state courts
of New Jersey shall have exclusive  jurisdiction  over any matter relating to or
arising  from this  Lease and the  parties'  rights and  obligations  under this
Lease.

    (b) No Waiver.  Landlord's  acceptance of Rent following an Event of Default
shall not waive Landlord's rights regarding such Event of Default.  No waiver by
Landlord of any violation or breach of any of the terms  contained  herein shall
waive Landlord's rights regarding any future violation of such term.  Landlord's
acceptance of any partial payment of Rent shall not waive Landlord's rights with
regard  to the  remaining  portion  of the Rent that is due,  regardless  of any
endorsement or other statement on any instrument delivered in payment of Rent or
any  writing  delivered  in  connection   therewith;   accordingly,   Landlord's
acceptance  of a partial  payment  of Rent  shall not  constitute  an accord and
satisfaction of the full amount of the Rent that is due.

    19. Landlord's Lien. Landlord hereby waives any statutory landlord's lien in
and to Tenant's equipment, inventory, furniture and fixtures.

                                  17

<PAGE>


    20. Surrender of Premises.  No act by Landlord shall be deemed an acceptance
of a surrender  of the  Premises,  and no agreement to accept a surrender of the
Premises  shall be valid unless it is in writing and signed by Landlord.  At the
expiration or  termination  of this Lease,  Tenant shall deliver to Landlord the
Premises with all  improvements  located  therein in good repair and  condition,
broom-clean,  reasonable wear and tear (and condemnation and Casualty damage not
caused by Tenant,  as to which Sections 13 and 14 shall control)  excepted,  and
shall  deliver to Landlord  all keys to the  Premises.  Tenant  shall remove all
unattached  trade  fixtures,  furniture,  and  personal  property  placed in the
Premises by Tenant, and shall remove such alterations,  additions, improvements,
trade  fixtures,  personal  property,  equipment,  and  furniture as required in
subparagraph 7(a). Tenant shall repair all damage caused by such removal and cap
any  fixtures  and/or  wiring that are  affected in the process of removing  the
foregoing.  All items not so removed  shall be deemed to have been  abandoned by
Tenant and may be appropriated,  sold, stored,  destroyed, or otherwise disposed
of by Landlord upon ten (10) days notice to Tenant and without any obligation to
account for such items.  The provisions of this Section 20 shall survive the end
of the Term.

    21.  Holding  Over. If Tenant fails to vacate the Premises at the end of the
Term,  then  Tenant  shall be a tenant at will  and,  in  addition  to all other
damages and remedies to which  Landlord  may be entitled for such holding  over,
Tenant shall pay, in addition to the other Rent, a daily Basic Rent equal to the
greater of (A) 150% of the daily Basic Rent payable during the last month of the
Term,  or (B) 125% of the  prevailing  basic  rental  rate in the  Building  for
similar space.

    22. Certain Rights Reserved by Landlord.  Provided that the exercise of such
rights does not unreasonably  interfere with Tenant's occupancy of the Premises,
Landlord shall have the following rights:

    (a) To decorate and to make inspections,  repairs,  alterations,  additions,
changes,  or  improvements,  whether  structural or otherwise,  in and about the
Building,  or any part  thereof;  to enter  upon the  Premises  and,  during the
continuance  of any such work, to  temporarily  close doors,  entryways,  public
space,  and  corridors in the  Building;  to interrupt  or  temporarily  suspend
Building  services and  facilities;  to change the name of the Building;  and to
change the  arrangement  and location of entrances or  passageways,  doors,  and
doorways,  corridors,  stairs, restrooms, or other public parts of the Building,
if any;

    (b) To take such  reasonable  measures as Landlord  deems  advisable for the
security of the Building and its  occupants;  evacuating the Building for cause,
suspected  cause,  or for  drill  purposes;  temporarily  denying  access to the
Building;  and closing the Building  after normal  business hours and on Sundays
and holidays,  subject, however, to Tenant's right to enter when the Building is
closed after normal business hours under such reasonable regulations as Landlord
may prescribe from time to time; and

    (c) To enter  the  Premises  at  reasonable  hours to show the  Premises  to
prospective  purchasers,  lenders,  or,  during  the last 12 months of the Term,
tenants.

                                  18

<PAGE>


    (d) Provided  Tenant is not in default under this Lease,  in connection with
any entry into the Premises for any purpose or in  connection  with any physical
work in or about the  Building  in the  vicinity  of the  Premises  which  might
interfere  with  Tenant's use and  enjoyment of the  Premises,  other than in an
emergency,  Landlord  shall:  (i) attempt to schedule any such  physical work by
appointment  with  Tenant at least a week after  verbally  advising  Tenant of a
mutually  satisfactory  time;  (ii)  use  reasonable  efforts  to  minimize  any
interference  with  Tenant's  use and  enjoyment of the Premises for its regular
business operations;  (iii) in connection with showing the Premises to others on
shorter  advice,  not seek to enter into  laboratory  portions  of the  Premises
without the explicit  permission  of Tenant in each  instance,  but be satisfied
with viewing the laboratory areas from the office areas through doors which will
have windows  installed in them for the purpose of viewing the laboratory  areas
from  the  office  areas;  and  (iv)  not  enter  the  laboratory  areas  if the
consequence  of doing so would be to  invalidate  any  pre-clinical  or clinical
trials in which  Tenant is then  engaged  and Tenant  notifies  Landlord of same
prior to the intended entry.

    23.  Intentionally Omitted.

    24.  Miscellaneous.

    (a) Landlord Transfer. Landlord may transfer any portion of the Building and
any of its rights  under this Lease.  If Landlord  assigns its rights under this
Lease,  then Landlord  shall  thereby be released  from any further  obligations
hereunder,  provided that the assignee assumes Landlord's  obligations hereunder
in writing.

    (b)  Landlord's  Liability.  The  liability  of  Landlord  to Tenant for any
default by Landlord under the terms of this Lease shall be recoverable only from
the interest of Landlord in the Building,  and Landlord  shall not be personally
liable for any  deficiency.  This  Section  shall not limit any  remedies  which
Tenant  may have for  Landlord's  defaults  which do not  involve  the  personal
liability of Landlord.

    (c) Force Majeure. Other than for Tenant's obligations under this Lease that
can be performed by the payment of money (e.g.,  payment of Rent and maintenance
of insurance),  whenever a period of time is herein  prescribed for action to be
taken by either party hereto, such party shall not be liable or responsible for,
and there shall be excluded from the computation of any such period of time, any
delays due to strikes, riots, acts of God, shortages of labor or materials, war,
governmental laws, regulations, or restrictions, or any other causes of any kind
whatsoever which are beyond the control of such party.

    (d)  Brokerage.  Neither  Landlord  nor  Tenant has dealt with any broker or
agent in connection with the negotiation or execution of this Lease,  other than
Newmark Partners, Inc. and Grubb & Ellis Company, whose commission shall be paid
by Landlord.  Tenant and Landlord  shall each  indemnify  the other  against all
costs,  expenses,  attorneys'  fees, and other liability for commission or other
compensation  claimed by any broker or agent claiming the same by,  through,  or
under the indemnifying party.

                                  19

<PAGE>


    (e) Estoppel  Certificates.  From time to time,  Tenant shall furnish to any
party designated by Landlord,  within ten days after Landlord has made a request
therefor,  a certificate signed by Tenant confirming and containing such factual
certifications and  representations as to this Lease, to the extent the same are
accurate, as Landlord may reasonably request.

    (f) Notices.  All notices and other  communications  given  pursuant to this
Lease shall be in writing and shall be (1) mailed by first class,  United States
Mail, postage prepaid,  certified,  with return receipt requested, and addressed
to the parties hereto at the address  specified next to their  signature  block,
(2) hand  delivered to the intended  address,  or (3) sent by prepaid  telegram,
cable,  facsimile  transmission,  or telex followed by a confirmatory  overnight
(i.e.,  Federal  Express or  equivalent)  letter with copies as indicated on the
signature  block. All notices shall be effective upon delivery to the address of
the addressee.  The parties  hereto may change their  addresses by giving notice
thereof to the other in conformity with this provision.

    (g)  Separability.  If any clause or  provision  of this  Lease is  illegal,
invalid,  or  unenforceable  under present or future laws, then the remainder of
this  Lease  shall  not be  affected  thereby  and in  lieu of  such  clause  or
provision, there shall be added as a part of this Lease a clause or provision as
similar in terms to such illegal,  invalid, or unenforceable clause or provision
as may be possible and be legal, valid, and enforceable.

    (h) Amendments;  and Binding Effect. This Lease may not be amended except by
instrument in writing signed by Landlord and Tenant.  No provision of this Lease
shall be deemed to have been  waived by either  party  unless  such waiver is in
writing signed by the putatively  waiving party, and no custom or practice which
may evolve between the parties in the  administration  of the terms hereof shall
waive or diminish  the right of either party to insist upon the  performance  by
Tenant in strict  accordance  with the terms  hereof.  The terms and  conditions
contained  in this Lease shall  inure to the benefit of and be binding  upon the
parties  hereto,  and upon their  respective  successors  in interest  and legal
representatives,  except as otherwise herein expressly  provided.  This Lease is
for the sole  benefit  of  Landlord  and  Tenant,  and,  other  than  Landlord's
Mortgagee, no third party shall be deemed a third party beneficiary hereof.

    (i) Quiet  Enjoyment.  Provided  Tenant has performed all of its obligations
hereunder,  Tenant shall  peaceably  and quietly hold and enjoy the Premises for
the Term, without hindrance from Landlord or any party claiming by, through,  or
under Landlord, subject to the terms and conditions of this Lease.

    (j) No  Merger.  There  shall be no merger of the  leasehold  estate  hereby
created  with the fee  estate in the  Premises  or any part  thereof if the same
person acquires or holds, directly or indirectly, this Lease or any

                                  20

<PAGE>


interest in this Lease and the fee estate in the leasehold Premises or any
interest in such fee estate.

    (k) No Offer.  The submission of this Lease to Tenant shall not be construed
as an offer,  and  Tenant  shall not have any rights  under  this  Lease  unless
Landlord executes a copy of this Lease and delivers it to Tenant.

    (l) Entire  Agreement.  This Lease  constitutes the entire agreement between
Landlord and Tenant  regarding the subject matter hereof and supersedes all oral
statements and prior writings  relating  thereto.  Except for those set forth in
this Lease,  no  representations,  warranties,  or agreements  have been made by
Landlord or Tenant to the other with respect to this Lease or the obligations of
Landlord or Tenant in connection therewith.

    (m) Waiver of Jury Trial. To the maximum extent  permitted by law,  Landlord
and Tenant each waive right to trial by jury in any litigation arising out of or
with respect to this Lease.

    (n)  Governing  Law.  This  Lease  shall be  governed  by and  construed  in
accordance with the laws of the State in which the Premises are located.

    (o) Joint and Several  Liability.  If Tenant is  comprised  of more than one
party,  each such  party  shall be jointly  and  severally  liable for  Tenant's
obligations under this Lease.

    (p) Financial Reports.  Within 15 days after Landlord's request, Tenant will
furnish Tenant's most recent audited financial  statements  (including any notes
to them) to Landlord, or, if no such audited statements have been prepared, such
other  financial  statements (and notes to them) as may have been prepared by an
independent  certified public accountant or, failing those,  Tenant's internally
prepared financial statements. Tenant will discuss its financial statements with
Landlord. Landlord will not disclose any aspect of Tenant's financial statements
that Tenant  designates  to Landlord as  confidential  except (a) to  Landlord's
lenders or  prospective  purchasers of the project,  (b) in  litigation  between
Landlord and Tenant, and (c) if required by court order.

    (q) Landlord's Fees. Whenever Tenant requests Landlord to take any action or
give any consent  required or permitted under this Lease,  Tenant will reimburse
Landlord for  Landlord's  reasonable  costs  incurred in reviewing  the proposed
action  or  consent,   including  without  limitation   reasonable   attorneys',
engineers' or  architects'  fees,  within 10 days after  Landlord's  delivery to
Tenant of a statement  of such  costs.  Tenant  will be  obligated  to make such
reimbursement  without regard to whether Landlord  consents to any such proposed
action.

   (r)  Intentionally Omitted.

                                  21

<PAGE>


    (s)  Confidentiality.  Tenant  acknowledges that the terms and conditions of
this Lease are to remain confidential for the Landlord's benefit, and may not be
disclosed by Tenant to anyone,  by any manner or means,  directly or indirectly,
without  Landlord's  prior written  consent.  The consent by the Landlord to any
disclosures  shall not be deemed to be a waiver on the part of the  Landlord  of
any prohibition against any future disclosure.

    (t) List of  Exhibits.  All  exhibits and  attachments  attached  hereto are
incorporated herein by this reference.

    Exhibit A -Legal Description and Outline of Premises
    Exhibit B -Building Rules and Regulations
    Exhibit C -Work Letter
    Exhibit D -Parking
    Exhibit E -Subordination, Non-Disturbance and Attornment Agreement/ Tenant
               Estoppel Certificate
    Exhibit F -Renewal Option
    Exhibit G -Right of First Offer
    Exhibit H -Letter of Credit

    (u) The  execution  and delivery of, the  consummation  of the  transactions
contemplated by and the performance of all its obligations  under, this Lease by
the Landlord have been duly and validly  authorized by all its general partners;
and  no  other  approval  or  consent,  whether  partnership,   governmental  or
otherwise,  is  required  to  authorize  or to  give  effect  to the  Landlord's
execution and delivery of, the consummation of the transactions  contemplated by
and the performance of all its obligations under, this Lease.

    25.  Other Provisions.

LANDLORD AND TENANT  EXPRESSLY  DISCLAIM ANY IMPLIED  WARRANTY THAT THE PREMISES
ARE SUITABLE FOR TENANT'S INTENDED COMMERCIAL  PURPOSE,  AND EXCEPT AS OTHERWISE
EXPRESSLY  PROVIDED  HEREIN,  TENANT  SHALL  CONTINUE  TO PAY THE RENT,  WITHOUT
ABATEMENT,  SETOFF OR DEDUCTION,  NOTWITHSTANDING  ANY BREACH BY LANDLORD OF ITS
DUTIES OR OBLIGATIONS HEREUNDER, WHETHER EXPRESS OR IMPLIED.

    26.  Environmental Laws.

    (a)  Tenant,  at its own  cost  and  expense,  agrees  to  comply  with  all
applicable  environmental  laws,  rules and  regulations of the Federal,  State,
County  and  Municipal  governments  and of all other  governmental  authorities
having or claiming  jurisdiction over the Premises or appurtenances  thereto, or
any part thereof,  which are  applicable  to the Premises  and/or the conduct of
business thereon (except that Tenant shall not be responsible for any occurrence
or condition  that arises prior to the  Commencement  Date),  including  but not
limited to the Environmental  Cleanup  Responsibility  Act of 1983 as amended by
the Industrial  Site Recovery Act (N.J.S.A.  13:1K-6 et seq) ("ISRA").  Further,
Tenant agrees to make submissions to and provide any information

                                  22

<PAGE>


required by all  governmental  authorities  requesting same pursuant to Tenant's
obligations under this Paragraph 26. Tenant represents to Landlord that Tenant's
Standard Industrial Classification (SIC) Number is 2835.

   (b) Tenant  hereby  agrees to execute such  documents as Landlord  reasonably
deems necessary and to make such applications as Landlord reasonably requires to
assure  compliance with ISRA.  Tenant shall bear all costs and expenses incurred
by Landlord associated with any required ISRA compliance resulting from Tenant's
use of the Premises including but not limited to state agency fees,  engineering
fees,  clean-up  costs,  filing fees and  suretyship  expenses.  As used in this
Lease,  ISRA compliance shall include,  but not be limited to,  applications for
determinations of  nonapplicability by the appropriate  governmental  authority.
The foregoing  undertaking shall survive the termination or sooner expiration of
the Lease and surrender of the Premises and shall also survive sale, or lease or
assignment  of the  Premises  by  Landlord.  Tenant  shall  immediately  provide
Landlord with copies of all correspondence,  reports, notices, orders, findings,
declarations  and other materials  pertinent to Tenant's  compliance and the New
Jersey Department of Environmental  Protection's  ("NJDEP")  requirements  under
ISRA as they are issued or received by the Tenant.

   (c) Tenant shall not generate, store, manufacture,  refine, transport, treat,
dispose  of, or  otherwise  permit to be present on or about the  Premises,  any
Hazardous  Substances unless the same are in full compliance with all applicable
environmental laws, rules and regulations.  As used herein, Hazardous Substances
shall be defined as any "hazardous  chemical,"  "hazardous substance" or similar
term as defined in the Comprehensive  Environmental  Responsibility Compensation
and  Liability  Act,  as  amended  (42  U.S.C.  9601,  et seq.),  the New Jersey
Environmental  Cleanup  Responsibility  Act, as amended by the  Industrial  Site
Recovery Act, (N.J.S.A.  13:1K-6 et seq.), the New Jersey Spill Compensation and
Control  Act,  as  amended,  (N.J.S.A.  58:10-23.11b,  et  seq.) , any  rules or
regulations promulgated thereunder, or in any other present or future applicable
federal,  state or local law,  rule or  regulation  dealing  with  environmental
protection.

   (d) In the event Tenant  receives any notice that a spill or discharge of any
Hazardous Substance has occurred on or about the Premises,  Building and/or Land
or into the sewer and/or waste  treatment  system  operated by Landlord from any
person or entity, including NJDEP and the United States Environmental Protection
Agency ("EPA"),  then Tenant shall provide  immediate  written notice of same to
Landlord, detailing all relevant facts and circumstances.

   (e) Tenant  agrees to  indemnify,  defend and hold  harmless the Landlord and
each  mortgagee  of the  Building  from  and  against  any and all  liabilities,
damages,  claims,  losses,  judgments,  causes of  action,  costs  and  expenses
(including the reasonable fees and expenses of counsel) which may be incurred by
the Landlord or any such  mortgagee or  threatened  against the Landlord or such
mortgagee,  relating  to or  arising  out of  the  presence,  disposal,  escape,
migration, leakage, spillage, discharge,  emission, release, threatened release,
handling,  or transportation of Hazardous Substances in, on, at, under, from, in
the vicinity of, or affecting or related to the Premises

                                  23

<PAGE>


or any part of the land and  Building  arising out of the acts or  omissions  of
Tenant, its employees,  contractors,  agents,  invitees and/or licensees and any
breach  by Tenant of this  Article,  which  indemnification  shall  survive  the
expiration  or sooner  termination  of this Lease.  In no event  shall  Tenant's
remedial action involve engineering or institutional controls, including without
limitation   capping,   deed  notice,   declaration   of  restriction  or  other
institutional  control notice pursuant to P.L. 1993, c.139, and  notwithstanding
NJDEP's  requirements,  Tenant's  remedial  action shall meet the most stringent
NJDEP remediation  standards for soil,  surface water and groundwater.  Promptly
upon completion of all required  investigatory and remedial  activities,  Tenant
shall restore the affected  areas of the land and  Buildings  from any damage or
condition caused by the work, including without limitation closing,  pursuant to
law any wells installed at the Building.

    (f) Environmental Report.  Landlord has provided to Tenant a copy of a Phase
I Environmental  Site Assessment  Update (SSCI Job No. 30238NJ)  ("Report") with
respect to the land upon which the Building is constructed,  dated June 6, 1996,
prepared by SSCI Environmental and Consulting  Services  ("Consultant").  Tenant
agrees  not to  release  the  Report,  or a copy of it,  or any  part of it,  or
disclose  any of the  information  contained  in the  Report to any third  party
(other than  Tenant's  counsel)  without the express  prior  written  consent of
Landlord.  Such  consent  shall  not be  unreasonably  withheld  as  long as the
proposed  party  to whom  the  report  is  given  executes  a  letter  agreement
containing covenants similar to this Section 26(f). Tenant releases Landlord for
any  inaccuracies,  omissions or errors  contained in the Report.  Tenant agrees
that it will  not  rely on the  Report  and it will  make  whatever  independent
investigation it feels is necessary to investigate the  environmental  and other
conditions  of the land.  Tenant  agrees that Landlord has no duty to provide it
with the Report, to correct any inaccuracies,  error or omissions in the Report,
to supplement the Report with any additional  information,  or to provide Tenant
with any information concerning the environmental conditions of the land. Tenant
agrees  that  Landlord  considers  the  Report  to be  confidential  proprietary
information  and Tenant agrees to maintain the  confidentiality  and security of
the  Report   information   in   accordance   with  the  highest   standards  of
confidentiality  and security associated with the protection of "trade secrets".
Landlord hereby expressly disclaims  responsibility for the investigation of the
land by Tenant and further disclaims any  responsibility for the contents of the
Report.  Tenant's  obligations  pursuant to this Section 26(f) shall survive the
expiration or termination of this Lease.




                                  24

<PAGE>


    27. Signs.  Tenant shall be entitled to be listed on the building  directory
and in a sign in front of the Premises comparable to signs
 provided to other tenants in the Building.

   IN WITNESS WHEREOF,  and in consideration of the mutual entry into this Lease
and for other  good and  valuable  consideration,  and  intending  to be legally
bound,  each party hereto has caused this Lease Agreement to be duly executed as
of the day and year first above written.


    TENANT:  PALATIN TECHNOLOGIES, INC.,
             a Delaware Corporation


    By:       /s/ Edward J. Quilty
             ----------------------------


   Notice Address:                       with a copy to:
   ------------------------------        --------------------------------
   Palatin Technologies, Inc.            Richard McCarthy, Esq.
   214 Carnegie Center, Suite 100        212 Carnegie Center, Suite 206
   Princeton, New Jersey 08540           Princeton, New Jersey 08543-8497
   Attn:  Chief Financial Officer        Telephone No.: 609-452-7877
   Telephone No.: 609-520-1911           Telecopy No.: 609-520-8731
   Telecopy No.: 609-452-0880


    LANDLORD: WHC-SIX REAL ESTATE LIMITED PARTNERSHIP,
              a Delaware limited partnership,

    By:       WHC-SIX Gen-Par, Inc., a Delaware
              corporation, its general partner


    By:        /s/ Wm. David Lawson
              ----------------------------
              Wm. David Lawson, Assistant Vice President


Notice Address:                            with a copy to:
- ---------------------------------------    ---------------------------------
WHC-Six Real Estate Limited Partnership    WHC-Six Real Estate Limited
c/o Newmark Partners, Inc.                   Partnership
1084 Route 22 West                         c/o Archon Group, L.P.
Mountainside, NJ 07092                     600 E. Las Colinas Boulevard,
Attn:  Property Manager                      Suite 1900
Telephone No.: 908-233-1717                Irving, Texas 75039
Telecopy No.: 908-233-7337                 Attn:  Asset Manager
                                           Telephone No.: 972-831-2200
                                           Telecopy No.: 962-831-2276

with a further copy to:
- -----------------------
Ravin, Sarasohn, Cook, Baumgarten, Fisch & Rosen, P.C.
103 Eisenhower Parkway
Roseland, New Jersey 07068
Attn:  Jeffrey D. Singer, Esq.
Telephone No.: 201-228-9600
Telecopy No.: 201-228-6081

<PAGE>


                                    EXHIBIT A





             [DIAGRAM OF FIRST FLOOR PLAN AND PROPERTY DESCRIPTION]



<PAGE>


                                    EXHIBIT B


                         BUILDING RULES AND REGULATIONS


   The  following  rules  and  regulations  shall  apply  to the  Premises,  the
Building, and the appurtenances thereto:

    1. Sidewalks,  doorways,  vestibules,  halls,  stairways,  and other similar
areas  shall not be  obstructed  by tenants  or used by any tenant for  purposes
other than ingress and egress to and from their  respective  leased premises and
for going from one to another part of the Building.

    2. Plumbing, fixtures and appliances shall be used only for the purposes for
which designed,  and no sweepings,  rubbish,  rags or other unsuitable  material
shall be thrown or deposited  therein.  Damage resulting to any such fixtures or
appliances from misuse by a tenant or its agents,  employees or invitees,  shall
be paid by such tenant.

    3. No signs,  advertisements or notices shall be painted or affixed on or to
any windows or doors or other part of the  Building  without  the prior  written
consent of  Landlord.  No nails,  hooks or screws shall be driven or inserted in
any part of the Building except by Building maintenance  personnel.  No curtains
or other window  treatments  shall be placed  between the glass and the Building
standard window treatments.

    4.  Landlord  shall provide and maintain an  alphabetical  directory for all
tenants in the Building directory.

    5. Landlord shall provide all door locks in each tenant's  leased  premises,
at the cost of such tenant,  and no tenant shall place any additional door locks
in its leased premises without Landlord's prior written consent.  Landlord shall
furnish  to each  tenant a  reasonable  number of keys to such  tenant's  leased
premises, at such tenant's cost, and no tenant shall make a duplicate thereof.

    6. Movement in or out of the Building of furniture or office  equipment,  or
dispatch or receipt by tenants of any bulky  material,  merchandise or materials
which  require use of elevators or stairways,  or movement  through the Building
entrances shall be conducted under  Landlord's  supervision at such times and in
such a manner as Landlord may reasonably require.  Each tenant assumes all risks
of and shall be liable for all damage to articles moved and injury to persons or
public engaged or not engaged in such movement,  including  equipment,  property
and  personnel  of  Landlord  if  damaged  or  injured  as a  result  of acts in
connection with carrying out this service for such tenant.




<PAGE>


    7. Landlord may prescribe weight limitations and determine the locations for
safes and other heavy equipment or items,  which shall in all cases be placed in
the Building so as to distribute weight in a manner acceptable to Landlord which
may include the use of such  supporting  devices as Landlord  may  require.  All
damages to the Building caused by the installation or removal of any property of
a  tenant,  or done by a  tenant's  property  while  in the  Building,  shall be
repaired at the expense of such tenant.

    8. Corridor doors,  when not in use, shall be kept closed.  Nothing shall be
swept or thrown into the  corridors,  halls,  elevator  shafts or stairways.  No
portion of any tenant's leased premises shall at any time be used or occupied as
sleeping or lodging quarters.

    9. Tenant shall  cooperate with  Landlord's  employees in keeping its leased
premises neat and clean.

    10. Intentionally omitted.

    11. Tenant shall not make or permit any vibration or improper, objectionable
or unpleasant noises or odors in the Building or otherwise  interfere in any way
with other tenants or persons having business with them.

    12. No  machinery  of any kind  (other  than  laboratory  and normal  office
equipment) shall be operated by any tenant on its leased area without Landlord's
prior  written  consent,  nor shall any tenant use or keep in the  Building  any
flammable or explosive fluid or substance,  unless required in Tenant's business
operations and then not in violation of applicable law.

    13. Landlord will not be responsible  for lost or stolen personal  property,
money or  jewelry  from  tenant's  leased  premises  or public  or common  areas
regardless of whether such loss occurs when the area is locked  against entry or
not.

    14. No vending or  dispensing  machines of any kind may be maintained in any
leased premises without the prior written permission of Landlord.

    15.  Tenant  shall  not  conduct  any  prohibited  activity  on or about the
Premises or Building which will draw pickets, demonstrators, or the like.

    16. All vehicles are to be currently licensed,  in good operating condition,
parked for business purposes having to do with Tenant's business operated in the
Premises, parked within designated parking spaces, one vehicle to each space. No
vehicle shall be parked as a "billboard" vehicle in the parking lot. Any vehicle
parked  improperly may be towed away. The Tenant,  Tenant's  agents,  employees,
vendors  and  customers  who do not  operate or park their  vehicles as required
shall  subject the vehicle to being towed at the expense of the owner or driver.
The Landlord may place a "boot" on the vehicle to  immobilize  it and may levy a
charge of $50.00 to remove the "boot". The Tenant shall indemnify, hold and save
harmless the Landlord of any liability arising from the towing or booting of any
vehicles  belonging  to the Tenant,  Tenant's  agents,  vendors,  employees  and
customers.


<PAGE>


                               EXHIBIT C

                              WORK LETTER

   1. The  Landlord  shall  make the  Premises  available  to the Tenant for the
purpose of build-out on the day  immediately  after the date the existing tenant
in the Premises vacates the Premises.

   2. As soon as practicable,  Tenant shall provide to Landlord for its approval
final  working  drawings,  prepared by an  architect  that has been  approved by
Landlord  (which  approval  shall  not  unreasonably  be  withheld,  delayed  or
conditioned),  of all  improvements  that  Tenant  proposes  to  install or have
installed in the  Premises.  Such working  drawings  shall include the partition
layout,  ceiling  plan,  electrical  outlets and  switches,  telephone  outlets,
drawings  for any  modifications  to the  electrical,  mechanical  and  plumbing
systems  of  the  Building,  and  detailed  plans  and  specifications  for  the
construction  of the  improvements  called for under this Exhibit in  accordance
with all applicable governmental laws, codes, rules and regulations. Further, if
any of Tenant's  proposed  construction  work will affect the  Building's  HVAC,
electrical,   mechanical,   or  plumbing  systems,  then  the  working  drawings
pertaining  thereto  must be  approved  by the  Building's  engineer  of record.
Landlord's approval of such working drawings shall not be unreasonably withheld,
delayed or conditioned,  provided that (a) they comply with all laws, rules, and
regulations,  and (b) such working drawings are  sufficiently  detailed to allow
construction  of the  improvements  in a good and  workmanlike  manner.  As used
herein,  "Working  Drawings" shall mean the final working  drawings  approved by
Landlord,  as amended from time to time by any  approved  changes  thereto,  and
"Work" shall mean all  improvements  to be constructed in accordance with and as
indicated on the Working Drawings.  Landlord's  approval of the Working Drawings
shall not be a  representation  or warranty of Landlord  that such  drawings are
adequate  for any use or comply with any law, but shall merely be the consent of
Landlord  thereto.  Landlord shall endorse the Working  Drawings to indicate its
review and  approval  thereof.  All  changes in the Work must  receive the prior
written  approval  of  Landlord,  and in the event of any such  approved  change
Tenant shall,  upon completion of the Work,  furnish  Landlord with an accurate,
reproducible "as-built" plan of the improvements as constructed.

   3. The Work  shall be  performed  by the  Tenant's  contractors  at  Tenant's
expense,  subject  to  the  Construction  Allowance  (and,  if  applicable,  the
Additional  Construction  Allowance)  hereinafter set forth. All of the Tenant's
contractors and their  subcontractors  shall be required to procure and maintain
insurance  against  such  risks,  in such  amounts  and with such  companies  as
Landlord may  reasonably  require.  Certificates  of such  insurance,  with paid
receipts  therefor,  must be received by Landlord  before the Work is commenced.
The Work shall be  performed in a good and  workmanlike  manner free of defects,
shall conform with the Working Drawings, and shall be performed in such a manner
and at such times as and not to materially  interfere  with or delay  Landlord's
other  contractors,  if any, the  operation of the  Building,  and the occupancy
thereof by other tenants.  All contractors  shall contact  Landlord on behalf of
themselves and their respective  subcontractors and schedule time periods during
which they may use Building  facilities  in  connection  with the Work;  and the
Landlord  shall  cooperate in such  scheduling  so as not to delay or hinder the
Work

<PAGE>


   4.  (a)  Landlord   shall   provide  to  Tenant  a   construction   allowance
("Construction  Allowance")  equal to $40.00  per  rentable  square  foot of the
Premises at the times and in the manner set forth below.

   (b) Landlord  shall make the  Construction  Allowance due with respect to the
9,000 square foot portion of the Premises available to Tenant,  either by paying
Tenant or its  contractors,  after Tenant shall have documented that it has been
billed  and  expended  $540,000.00  for  the  build-out.  Tenant  shall  forward
documented  invoices to Landlord  not more  frequently  than monthly and payment
shall be made as  expeditiously  as practicable  upon  Landlord's  receipt of an
invoice and lien waivers from any contractors,  subcontractors  and suppliers of
the Work.

   (c) Landlord  shall make the  Construction  Allowance due with respect to the
Balance  of Suite 500  available  to  Tenant,  either  by  paying  Tenant or its
contractors,  when (i) Tenant builds out the Balance of Suite 500 to completion,
and (ii) the Total  Occupancy  Date shall have  occurred.  Tenant shall  forward
documented  invoices to Landlord  not more  frequently  than monthly and payment
shall be made as  expeditiously  as practicable  upon  Landlord's  receipt of an
invoice and lien waivers from any contractors,  subcontractors  and suppliers of
the Work.

   5.  Landlord  shall provide to Tenant an  additional  construction  allowance
("Additional  Construction  Allowance")  equal to 100% of all the rent and other
premiums  actually received  (including but not limited to retroactive  holdover
rent and premiums), without Landlord having any obligation to commence a lawsuit
therefor,  from the existing  tenant in the Premises as it pertains to Suite 500
(as  opposed  to the entire  space  occupied  by the  existing  tenant)  paid or
attributable  to the period  from and after  April 1, 1997 (and any  retroactive
period  prior  thereto)  with  respect  to  the  Premises,  up to a  maximum  of
$35,000.00,  for the  limited  purpose of  reimbursing  Tenant  for  incremental
verified  costs  incurred  by the Tenant in its  discretion  for the  purpose of
accelerating  construction  of the  build-out  contemplated  to begin  after the
existing tenant in the Premises vacates the Premises,  including  overtime labor
expense,  expediting  charges  and  similar  costs  incurred  for the purpose of
accelerating construction.  Tenant shall forward documented invoices to Landlord
not more  frequently  than  monthly and payment of the  Additional  Construction
Allowance shall be made as expeditiously as practicable upon Landlord's  receipt
of invoices and lien waivers from any contractors,  subcontractors and suppliers
of the Work setting forth such costs in the aggregate amount of such costs.

   6. If the existing Tenant in the Premises shall not have vacated the Premises
by the close of business on April 15, 1997, the Landlord shall promptly commence
summary  dispossession  proceedings by filing the summons and complaint with the
Clerk  of the  Court  on the  next  business  day and  pursue  such  proceedings
diligently and  expeditiously,  with the goal of evicting the existing tenant in
the Premises  from the Premises at the  earliest  possible  date after April 15,
1997.

<PAGE>


                               EXHIBIT D


                                PARKING


   Tenant  may  use  40  non-designated  parking  spaces  in  the  parking  area
associated  with the  Building  (the  "Parking  Area")  during the initial  Term
subject  to such  terms,  conditions  and  regulations  as are from time to time
applicable to patrons of the Parking Area.







<PAGE>

 
                               EXHIBIT E

                    SUBORDINATION, NON-DISTURBANCE
                       AND ATTORNMENT AGREEMENT

         THIS AGREEMENT is made and entered into as of the _________ day
of _________________, 1997 by and between GENERAL ELECTRIC CAPITAL
REALTY GROUP, a New York corporation ("Mortgagee"), and PALATIN
TECHNOLOGIES, INC., a Delaware Corporation ("Lessee").

R E C I T A L S:

         A. Mortgagee has provided an acquisition and development loan
("Loan") to WHC-SIX Real Estate Limited Partnership, Owner/Lessor
("Borrower"), for the purpose of financing Borrower's acquisition
and development of the Edison Corporate Center in Edison, New Jersey
and described in Exhibit A attached hereto and incorporated herein by
reference (said real property and improvements being herein called
the "Project"), such Loan being secured by a First Mortgage and
Security Agreement dated July 29, 1994 and recorded in Mortgage Book
4772, Page 295 seq., in the Clerk's Office of Middlesex County, (the
"Mortgage"), constituting a lien or encumbrance on the Project; and

         B. Lessee is the holder of a Leasehold estate in and to Suite
500 of 125 May Street, Edison, New Jersey, of the Project, consisting
of 10,538 square feet of space (the "Demised Premises"), under that
lease dated March 13, 1997 (the "Lease") executed by Borrower, as
Landlord (Borrower being sometimes hereinafter called "Lessor"), and
Lessee, as Tenant; and

         C. Lessee and Mortgagee desire to confirm their understandings
with respect to the Lease and Mortgage.

AGREEMENT:

         NOW, THEREFORE, in consideration of the foregoing and the mutual
covenants and agreements herein contained, Lessee and Mortgagee agree
and covenant as follows:

         1. Non-Disturbance. Mortgagee agrees that it will not disturb
the possession of Lessee under the Lease upon any judicial or non-
judicial foreclosure of the Mortgage or upon acquiring title to the
Project by deed-in-lieu of foreclosure, or otherwise, if the Lease is
in full force and effect and Lessee is not then in default under the
Lease, and that Mortgagee will accept the attornment of Lessee
thereafter so long as Lessee is not in default under the Lease.

         2. Attornment. If the interests of Lessor in and to the Demised
Premises are owned by Mortgagee by reason of any deed-in-


<PAGE>


lieu of foreclosure, judicial foreclosure, sale pursuant to any
power of sale or other proceedings brought by it or by any other
manner, including, but not limited to, Mortgagee's exercise of its
rights under any assignment of leases and rents, and Mortgagee
succeeds to the interest of Lessor under the Lease; Lessee shall be
bound to Mortgagee under all of the terms, covenants and conditions
of the Lease for the balance of the term thereof remaining and any
extension thereto duly exercised by Lessee with the same force and
effect as if Mortgagee were the Lessor under the Lease, and Lessee
does hereby attorn to Mortgagee, as its lessor, said attornment to be
effective and self-operative, without the execution of any further
instruments on the part of any of the parties hereto, immediately
upon Mortgagee's succeeding to the interest of Lessor under the
Lease; provided, however, that Lessee shall be under no obligation to
pay rent to Mortgagee until Lessee receives written notice from
Mortgagee that Mortgagee has succeeded to the interest of the Lessor
under the Lease or otherwise has the right to receive such rents. The
respective rights and obligations of Lessee and Mortgagee upon such
attornment, to the extent of the then remaining balance of the term
of the Lease, shall be and are the same as now set forth therein, it
being the intention of the parties hereto for this purpose to
incorporate the Lease in this Agreement by reference, with the same
force and effect as if set forth in full herein.

         3. Mortgagee's Obligations. If Mortgagee shall succeed to the
interest of Lessor under the Lease, Mortgagee, subject to the last
sentence of this Paragraph 3, shall be bound to Lessee under all of
the terms, covenants and conditions of the Lease, provided, however,
that Mortgagee shall not be:

          (a) Liable for any act or omission of any prior lessor
(including Lessor) but not withstanding such lack of liability, upon
Mortgagee (i) succeeding to the interest' of Lessor under the Lease,
and (ii) receiving written notice of the act or omission from Lessee,
Mortgagee shall commence to cure any act or omission of any prior
lessor (including Lessor); or

          (b) Subject to the offsets or defenses which Lessee might have
against any prior lessor (including Lessor) but not withstanding such
lack of liability, upon Mortgagee (i) succeeding to the interest of
Lessor under the Lease, and (ii) receiving written notice of the act
or omission from Lessee, Mortgagee shall commence to cure any act or
omission of any prior lessor (including Lessor); or,

                                        2


<PAGE>



          (c) Bound by any rent or additional rent or advance rent which
Lessee might have paid in advance in excess of one month's rent to
any prior lessor (including Lessor), and all such rent shall remain
due and owing, notwithstanding such advance payment; or

          (d) Bound by any security or advance rental deposit made by
Lessee which is not delivered or paid over to Mortgagee and with
respect to which Lessee shall look solely to Lessor for refund or
reimbursement; or

          (e) Bound by any termination, amendment or modification of the
Lease made without its consent and written approval.

Neither General Electric Capital Corporation nor any other party who
from time to time shall be included in the definition of Mortgagee
hereunder, shall have any liability or responsibility under or
pursuant to the terms of this Agreement after it ceases to own an
interest in the Project with respect to acts and omissions of its
successor in interest that occur after the effective date of such
cessation. Nothing in this Agreement shall be construed to require
Mortgagee to see to the Application of the proceeds of the Loan, and
Lessee's agreements set forth herein shall not be impaired on account
of any modification of the documents evidencing and securing the
Loan. Lessee acknowledges that Mortgagee is obligated only to
Borrower to make the Loan only upon the terms and subject to the
conditions set forth in the Loan Agreement between Mortgagee and
Borrower pertaining to the Loan. Lessee further acknowledges and
agrees that neither Mortgagee nor any purchaser of the Project at
foreclosure sale or any grantee of the Project named in a deed-in-
lieu of foreclosure nor any heir, legal representative, successor, or
assignee of Mortgagee or any such purchaser or grantee, has or shall
have any personal liability for the obligations of Lessor under the
Lease; provided, however, that the Lessee may exercise any other
right or remedy provided thereby or by law in the event of any
failure by Lessor to perform any such material obligation.

     4.   Subordination.  The Lease and all rights of Lessee
thereunder are subject and subordinate to the Mortgage and to any
deeds of trust, mortgages, ground leases or other instruments of
security which do now or may hereafter cover the Project or any
interest of Lessor therein (collectively, the "Prior Encumbrances")
and to any and all advances made on the security thereof and to any
and all increases, renewals, modifications, consolidations,
replacements and extensions of the Mortgage or of any of the Prior
Encumbrances. This provision is acknowledged by Lessee to be self-
operative and no further instrument shall be required to

                                        3


<PAGE>



effect such subordination of the Lease. Lessee shall, however, upon
demand at any time or times execute, acknowledge and deliver to
Mortgagee any and all instruments and certificates that in
Mortgagee's judgment may be necessary or proper to confirm or
evidence such subordination provided none of such certificates
contains any provision that purports to increase Lessee's obligations
or diminish Lessee's rights (including rights of rent abatement as
specifically stated under the Lease) and provided such certificates
are reasonably satisfactory in form and substance to Lessee. If
Lessee shall fail or neglect to execute, acknowledge and deliver any
such instrument or certificate, Mortgagee may, in addition to any
other remedies Mortgagee may have, as agent and attorney-in-fact of
Lessee, execute, acknowledge and deliver the same and Lessee hereby
irrevocably appoints Mortgagee as Lessee's agent and attorney-in-fact
for such purpose. However, notwithstanding the generality of the
foregoing provisions of this paragraph, Lessee agrees that Mortgagee
shall have the right at any time to subordinate the Mortgage, and any
such other mortgagee or ground lessor shall have the right at any
time to subordinate any such Prior Encumbrances, to the Lease.

         5. New Lease. Upon the written request of either Mortgagee or
Lessee to the other given at the time of any foreclosure, trustee's
sale or conveyance in lieu thereof, the parties agree to execute a
lease of the Demised Premises upon the same terms and conditions as
the Lease between Lessor and Lessee, which lease shall cover any
unexpired term of the Lease existing prior to such foreclosure,
trustee's sale or conveyance in lieu of foreclosure, provided the
terms and conditions of any such new lease are substantively the same
as in the Lease and do not increase Lessee's economic obligations.

         6. Notice. Lessee agrees to give written notice to Mortgagee of
any default by Lessor or Borrower under the Lease not less than
thirty (30) days prior to terminating the Lease or exercising any
other right or remedy thereunder or provided by law. Lessee further
agrees that it shall not terminate the Lease or exercise any such
right or remedy provided such default is cured within thirty (30)
days; provided, however, that if such default cannot by its nature be
cured within thirty (30) days, then Lessee shall not terminate the
Lease or exercise any such right or remedy, provided the curing of
such default is commenced within such thirty (30) days and is
diligently prosecuted thereafter. Such notices shall be delivered by
certified mail, return receipt requested to

                     General Electric Capital Realty Group
                     Attn: Mike Jaynes
                     15479 Dallas Parkway, Suite 400

                                        4


<PAGE>



                     Dallas, Texas 75248-2661

         7. Mortgagee. The term "Mortgagee" shall be deemed to include
General Electric Capital Realty Group and any of its successors and
assigns, including anyone who shall have succeeded to Lessor's
interest in and to the Lease and the Project by, through or under
judicial foreclosure or sale under any power or other proceedings
brought pursuant to the Mortgage, or deed in lieu of such foreclosure
or proceedings, or otherwise.

         8. Estoppel. Lessee hereby certifies, represents and warrants
to Mortgagee that:

          (a) That the Lease is a valid lease and in full force and
effect. That it is not aware of any existing default in any of the
terms and conditions thereof and no event has occurred which, with
the passing of time or giving of notice or both, would constitute an
event of default;

          (b) That the Lease has not been amended, modified,
supplemented, extended, renewed or assigned by Lessee, and represents
the entire agreement of the parties;

          (c) That, except, as provided in the Lease, Lessee is entitled
to no rent concessions or abatements;

          (d) That Lessee shall not pay rental under the Lease in excess
of one (1) month's rent in advance (except for any deposit or letter
of credit in the nature of security. Lessee agrees that Lessee shall,
upon written notice by Mortgagee, pay to Mortgagee, when due, all
rental due under and in accordance with the Lease;

          (e) That all obligations and conditions under the Lease to be
performed to date have been satisfied, free of defenses and set-offs;
and

          (f) That Lessee has not received written notice of any claim,
litigation or proceedings, pending or threatened, against or relating
to -Lessee, or with respect to the Demised Premises which would
affect its performance under the Lease. Lessee has not received
written-notice of any-violations of any federal, state, county or
municipal statutes, laws, codes, ordinances, rules, regulations,
orders, decrees or directives relating to the use or condition of the
Demised Premises or Lessee's operations thereon.

          (g)   On the date or this Agreement, the proposed lease has
been executed by Lessee and forwarded to Lessor for execution and an
executed copy returned to Lessee.  Until execution by Lessor and
return of an executed copy to Lessee, the Lease will not have become
effective.  Paragraphs 8(a) through (e) above should be read in light
of this paragraph 8(g).


                                        5

<PAGE>


          9. Modification and Successors. This Agreement may not be
modified orally or in any manner other than by an agreement, in
writing, signed by the parties hereto and their respective successors
in interest. This Agreement shall inure to the benefit of and be
binding upon the parties hereto, their successors and assigns.

         10. Counterparts. This Agreement may be executed in several
counterparts, and all so executed shall constitute one agreement,
binding on all parties hereto, notwithstanding that all parties are
not signatories to the original or the same counterpart.

         IN WITNESS WHEREOF, the parties hereto have executed this
Agreement as of the day and year first above written.

MORTGAGEE:                     GENERAL ELECTRIC CAPITAL REALTY GROUP,
                               a New York corporation

                               By:
                                  ---------------------------------

                               Its
                                  ---------------------------------

LESSEE:                        PALATIN TECHNOLOGIES, INC.
                               a Delaware corporation



                               By: /s/ Edward J. Quilty
                                  ----------------------


                                        6



<PAGE>


STATE OF TEXAS         )
                       )Ss.
COUNTY OF DALLAS       )

     BE IT REMEMBERED, that on this ____ day of _____, 1997, before me
the subscriber,_____________________, personally appeared_____________
who, I am satisfied, is the person who signed the within instrument
as __________________________ of General Electric Capital Realty Group,
a New York Corporation, the entity named therein and he thereupon
acknowledged that the said instrument made by the corporation and sealed
with its corporate seal, was signed, sealed with the corporate seal and
delivered by him as such officer and is the voluntary act and deed of the
corporation, made by virtue of authority from its Board of Directors.


_______________________
Notary Public, in and
for the State of Texas

My Commission expires ___________


STATE OF NEW JERSEY      )
                         )ss.
COUNTY OF MERCER         )

      BE IT REMEMBERED, that on this 31st day of March, 1997, before me
the subscriber, Janet R. Schneider, personally appeared Edward J. Quilty
who, I am satisfied, is the person who signed the within instrument as
the CEO of Palatin Technologies, Inc., the entity named therein and he
thereupon acknowledged that the said instrument made by the corporation
and sealed with its corporate seal, was signed, sealed with the corporate
seal and delivered by him as such officer and is the voluntary act and
deed of the corporation, made by virtue of authority from its Board of
Directors.


 /s/ Janet R. Schneider
- ------------------------
Notary Public, in and for
the State of

My Commission expires _________



Janet R. Schneider
NOTARY PUBLIC OF NEW JERSEY
MY COMMISSION EXPIRES JULY 31, 2000


                                        7


<PAGE>


                                    EXHIBIT E
                      GENERAL ELECTRIC CAPITAL REALTY GROUP
                          TENANT'S ESTOPPEL CERTIFICATE
                          -----------------------------


PREMISES: Edison Corporate Center, 125 May Street, Suite 500
          (10,538 square feet), Edison, New Jersey ("PREMISES")

LANDLORD: WHC-Six Real Estate L.P., a Delaware limited partnership
          ("LANDLORD")

LEASE DATED:  March 13, 1997 ("LEASE")

TENANT: Palatin Technologies, Inc., a Delaware corporation
        ("TENANT")

TENANT`S NOTICE ADDRESS: 214 Carnegie Center, Suite 100.
                         Princeton, New Jersey 08540

  DATE: __________________, 1997

         The undersigned, Tenant, hereby certifies to GENERAL ELECTRIC
CAPITAL REALTY GROUP, a New York corporation ("GECRG"), that:

1.   Tenant shall accept possession of the Premises pursuant to the
Lease. The Lease term shall commence on the earlier of (i) ninety-seven
(97) days following the date that the existing tenant in the Premises
vacates the Premises or (ii) the date-a temporary or permanent
certificate of occupancy is issued for the Initial Portion of Premises
(9,000 square feet) ("Commencement Date"). The termination date of the
Initial Term of the Lease is ten (10) years following the Commencement
Date. If the Commencement Date is not the first day of a calendar month,
then the Term shall be extended for the number of days between the
Commencement Date and the first day of the following month. Subject to
the Basic Rent adjustment as provided in paragraph 3(a)(ii) of the Lease,
monthly rent under the Lease is as follows: Basic Rent, $9,640.83 per
month for months 1-12, $9,897.17 per month for months 13-24, $10,538.00
per month for months 25-36, $13,:72.50 per month for months 37-60,
$16,685.17 per month for months 61-120, plus additional rent as provided
in the Lease.

2.   Any improvements-required by the terms of the Lease to be made by
Landlord prior to the Commencement Date with respect to the Premises have
been completed to the satisfaction of Tenant in all respects, and
Landlord has fulfilled all of its duties under the Lease, performance of
which was due prior to the date of this certificate.

3.   The Lease has not been assigned, modified, supplemented or amended
in any way by the Tenant. The Lease constitutes the entire agreement
between the parties and


<PAGE>


there are no other agreements between Landlord and Tenant concerning the
Premises.

4.   The Lease is valid and in full force and effect, and, to the best of
Tenant's knowledge, neither Landlord nor Tenant is in default thereunder.
Tenant has no defense, setoff or counterclaim against Landlord arising
out of the Lease or in any way relating thereto, or arising out of any
other transaction between Tenant and Landlord, and no event has occurred
and no condition exists, which, with the giving of notice or the passage
of time, or both, will constitute a default under the Lease.

5.   No rent or other sum payable to Landlord under the Lease has been
paid in advance in excess of an amount equal to one month's Basic Rent,
except for any deposit or letter of credit in the nature of security.

6.   The minimum monthly rental rate presently payable under the Lease on
and after the Commencement Date is $9,640.83.

7.   Tenant acknowledges that Tenant has received this Estoppel
Certificate as notice that the Lease will be assigned to GECRG and Tenant
has received no notice of a prior assignment, hypothecation or pledge of
the Lease or the rents, income, deposits or profits arising thereunder.
GECRG hereby advises, and Tenant understands, that under the provisions
of the assignment, the Lease cannot be terminated (either directly or by
the exercise of any option which could lead to termination) or modified
in any of its terms, or consent be given to the release of any party
having liability thereon, without the prior written consent of GECRG,
that without such consent, no rent may be collected or-accepted in excess
of one month's rent in advance and that the interest of the Landlord in
the Lease has been assigned to GECRG solely as security for the purposes
specified in the assignment and GECRG assumes no duty, liability or
obligations whatever under the Lease or any extension or renewal thereof.

8.   Tenant hereby acknowledges and agrees that if GECRG shall succeed to
the interest of Landlord under the Lease, GECRG shall assume (only while
owner of and in possession or control of the building of which the
Premises are a part) and perform all of Landlords obligations under the
Lease, but, except as may otherwise specifically set forth in the
Subordination, Non-Disturbance and Attornment Agreement between GECRG and
the Tenant, or elsewhere in this certificate shall not be liable for any
act or omission of any prior landlord (including the present landlord),
liable for the return of any security deposit, subject to any offset or
defense which Tenant



<PAGE>


may have against any such prior landlord or bound by any rent or
additional rent Tenant may have paid for more than the current month to
any such prior landlord or bound by any assignment, surrender,
termination, cancellation, waiver, release, amendment or modification of
the Lease made without its express written consent.

9.   Tenant shall give GECRG prompt written notice of any default of
Landlord under the Lease, if such default entitles Tenant, under law or
otherwise, to terminate the Lease, reduce rent or credit or offset any
amount against future rents and shall give GECRG reasonable time (but in
no event less than 30 days after receipt of such notice) to cure or
commence curing such default prior to exercising (and as a condition
precedent to its right to exercise), any right Tenant may have to
terminate the Lease or to reduce rent or credit or offset any amounts
against the rent. Tenant shall give written notice of any default of
Landlord to any successor in interest of GECRG, any purchaser at a
foreclosure sale under the mortgage, any transferee who acquired the
property by deed in lieu of foreclosure or any successor or assign
thereof of whose name and address Tenant shall have been advised by
written notice from GECRG or its then current successor in interest.

10.   Tenant shall not look to the Mortgagee, as mortgagee, mortgagee in
possession, or successor in title to the Mortgaged Property, in
connection with the return of or accountability with respect to any
security deposit required by Landlord, unless said sums have actually
been received by Mortgagee as security for Tenant's performance under the
Lease.

11.   Tenant shall neither suffer nor itself manufacture, store, handle,
transport, dispose of, spill, leak, dump any toxic or hazardous waste,
waste product or substance (as they may be defined in any federal or
state statute, rule or regulation pertaining to or governing such wastes,
waste products or substances) on the Mortgaged Property at any time
during the term, or extended term, of the Lease, except as permitted by
the Lease.

12.   All notices and other communications from Tenant to GECRG shall be
in writing and shall be delivered or mailed by registered mail, postage
paid, return receipt requested, addressed to GECRG at:

       General Electric Capital Realty Group
       Attn: Mike Jaynes
       16479 Dallas Parkway, Suite 400
       Dallas, Texas 75248-2661



<PAGE>


or at such other address as GECRG, any successor, purchaser or transferee
shall furnish to Tenant in writing.

13.   This Estoppel Certificate is being executed and delivered by
Tenant(s) for the benefit of GECRG in connection with its loan to
Landlord which, Tenant is informed by GECRG, is secured or to be secured
in part by an assignment to GECRG of Landlord's interest in the Lease,
and (b) with the intent and understanding that the above statements will
be relied upon by GECRG.

14.   On the date of this certificate, the proposed Lease has been
executed by Tenant and forwarded to Landlord for execution an an executed
copy returned to Tenant.  Until execution by Landlord and return of an
executed copy to tenant, the Lease will not have become effective and no
obligations of Landlord or Tenant will have arisen under the Lease.  The
foregoing Certificate should be read in light of this paragraph 14, e.g.,
paragraph 2, no improvements have been made (or buildout allowance paid)
because performance thereof was not due as of the Certificate date.


TENANT:                          Palatin Technologies, Inc.
                                 a Delaware corporation


                                      /s/ Edward J. Quilty
                                 By:-----------------------

<PAGE>


                                    EXHIBIT F


                                 RENEWAL OPTION


(a)     Renewal.  Provided no Event of Default exists, Tenant shall have
        option(s) ("Renewal Option(s)") to extend the term of this Lease for
        two (2) additional periods of five (5) years each ("Renewal Term(s)"),
        by giving Landlord notice thereof not more than twelve (12), but at
        least nine (9) months' notice, prior to the date of expiration of the
        then current term of this Lease.  If Tenant shall exercise the Renewal
        Option(s), then this Lease shall be extended for the then upcoming
        Renewal Term upon all of the terms, covenants and conditions contained
        in this Lease, except that, during the Renewal Term, the annual Basic
        Rent for said term shall be 95% of the annual market rental value
        ("Market Value Rent") of the Premises on the date that Tenant
        exercises the applicable Renewal Option ("Exercise Date"), determined
        as provided in subparagraph (b) below.  In calculating the Market
        Value Rent, the following assumptions shall be made:  (i) the Landlord
        can deliver possession of the Premises on the first day of the
        respective Renewal Term; (ii) the Premises or respective portions
        thereof are in the same condition they were in immediately after the
        completion of any build-out thereof, subject to normal wear and use,
        and the Tenant would accept them in that condition without any further
        improvement; (iii) the improvements then in place in the Premises have
        no special value to the Tenant beyond the value they would have to a
        reasonable willing tenant seeking combination office and laboratory
        space; (iv) this Lease remains in effect in accordance with its terms;
        (v) the Landlord is required to pay a standard brokerage commission
        with respect to the respective Renewal Term; and (vi) the Landlord
        will be granting no concessions during the respective Renewal Term.

(b)     Arbitration.  The term "Market Value Rent" shall mean the annual fixed
        rent that a willing tenant would pay and a willing landlord would
        accept in an arms-length lease of the Premises as of the Exercise
        Date, assuming the same terms and conditions set forth in this Lease
        and using the assumptions described in (a) above.  If Landlord and
        Tenant shall fail to agree upon the Market Value Rent within sixty
        (60) days after the Exercise Date, then Landlord and Tenant each shall
        give notice ("Determination Notice") to the other setting forth their
        respective determinations of the Market Value Rent, and, subject to
        the provisions of subparagraph (c) below, either party may apply to
        the American Arbitration Association or any successor thereto for the
        designation of an arbitrator satisfactory to both parties to render a
        final determination of the Market Value Rent.  If Landlord and Tenant
        cannot agree upon an arbitrator, the parties shall jointly apply to
        the assignment judge of Middlesex County to select an arbitrator.  The
        arbitrator shall be a real estate appraiser, consultant or broker who
        shall have at least fifteen (15) years continuous experience in the
        business of appraising or office and laboratory leasing.  The
        arbitrator shall conduct such hearings and investigations as the
        arbitrator shall deem appropriate and shall, within thirty (30) days
        after having been

<PAGE>


        appointed,  choose  one  of  the  determinations  set  forth  in  either
        Landlord's  or  Tenant's  Determination  Notice,  and that choice by the
        arbitrator  shall be binding upon Landlord and Tenant.  Each party shall
        pay its own counsel fees and expenses,  if any, in  connection  with any
        arbitration  under this  subparagraph  (b), and the parties  shall share
        equally  all  other  expenses  and  fees of any  such  arbitration.  The
        determination  rendered  in  accordance  with  the  provisions  of  this
        subparagraph  (b) shall be final and binding in fixing the Market  Value
        Rent.  The  arbitrator  shall  not have the  power to add to,  modify or
        change any of the provisions of this Lease.

(c)     Arbitration cancelled.  In the event that the determination of the
        Market Value Rent set forth in the Landlord's and Tenant's
        Determination Notices shall differ by less than three (3%) percent per
        rentable square foot per annum for the applicable Renewal Term, then
        the Market Value Rent shall not be determined by arbitration, but
        shall instead be set by taking the average of the determination set
        forth in Landlord's and Tenant's Determination Notices.  Only if the
        determinations set forth in Landlord's and Tenant's Determination
        Notices shall differ by more than three (3%) percent per rentable
        square foot per annum for the applicable Renewal Term shall the actual
        determination of Market Value Rent be made by an arbitrator as set
        forth in subparagraph (b) above.

(d)     Late determination.  If for any reason the Market Value Rent shall not
        have been determined prior to the commencement of the Renewal Term,
        then, until the Market Value Rent and, accordingly, the annual Basic
        Rent, shall have been finally determined, the annual Basic Rent shall
        remain the same as payable during the last year of the expiring term
        of the Lease.  Upon final determination of the Market Value Rent, an
        appropriate adjustment to the annual Basic Rent shall be made
        reflecting such final determination, and Landlord or Tenant, as the
        case may be, shall promptly refund or pay to the other any overpayment
        or deficiency, as the case may be, in the payment of annual Basic Rent
        from the commencement of the Renewal Term to the date of such final
        determination.

(e)     In the event the  Premises  has been  expanded,  the  Renewal  Option(s)
        contained herein shall apply to the then existing Premises,  as expanded
        on a co-termination basis.

(f)     Tenant shall have no further renewal options unless expressly granted by
        Landlord in writing.

(g)     Landlord  shall  lease to  Tenant  the  Premises  in their  then-current
        condition,  and  Landlord  shall not  provide to Tenant  any  allowances
        (e.g., moving allowance,  construction allowance, and the like) or other
        tenant inducements.

(h)     Tenant's  rights under this Exhibit  shall  terminate if Tenant fails to
        timely  exercise its  option(s)  under this  Exhibit,  time being of the
        essence with respect to Tenant's  exercise thereof or Tenant assigns any
        of its  interest in this Lease or sublets  any portion of the  Premises,
        other than an assignment or subletting to an Affiliate.

(i)     In no event  shall  Tenant be  entitled  to  exercise  an option for any
        Renewal Term unless it or an Affiliate is occupying all of the  Premises
        at the time of exercise.

<PAGE>


                               EXHIBIT G


                         RIGHT OF FIRST OFFER


   Subject to then-existing  renewal or expansion options of other tenants,  and
the  existing  tenants'  desires  (whether or not set forth in their  leases) to
extend their terms  provided no Event of Default then  exists,  Landlord  shall,
prior to  offering  the same to others,  and first  offer to lease to Tenant the
space  designated  on page 2 of this Exhibit  (the "Offer  Space") in an "AS-IS"
condition;  such offer  shall be in writing  and specify the rent to be paid for
the Offer  Space and the date on which the Offer  Space shall be included in the
Premises (the "Offer  Notice").  Tenant shall notify Landlord in writing whether
Tenant  elects to lease the entire  Offer  Space at the rental rate set forth in
the Offer  Notice,  within 10 days after  Landlord  delivers to Tenant the Offer
Notice.  If Tenant  timely  elects to lease the Offer Space,  then  Landlord and
Tenant shall  execute an  amendment to this Lease,  effective as of the date the
Offer Space is to be included in the  Premises,  on the same terms as this Lease
except as follows:

   (a) the rentable  area of the Premises  and Tenant's  proportionate  share of
   applicable  Rent  obligations  shall be increased by the rentable area in the
   Offer Space;

   (b) the Basic Rent shall be increased by the amount  specified for such space
   in the Offer Notice;

   (c)  Landlord  shall not  provide  to Tenant  any  allowances  (e.g.,  moving
   allowance, construction allowance, and the like) or other tenant inducements;
   and

   (d) The Term shall be co-terminous with the Premises.

   If Tenant  fails or is unable to timely  exercise its right  hereunder,  then
such right shall  forever  lapse,  time being of the essence with respect to the
exercise  thereof,  and Landlord  may lease the Offer Space to third  parties on
such terms as Landlord may elect provided  Landlord  initially  offers the Offer
Space to the  third  parties  upon the same  terms as  offered  to  Tenant,  but
Landlord shall be entitled to conclude its  transaction  with the third party on
terms other than initially  offered to the third party.  Tenant may not exercise
its  rights  under this  Exhibit  if an Event of Default  exists or Tenant or an
Affiliate is not then occupying the entire Premises.

   Tenant's  rights  under this  Exhibit  shall  terminate  if (a) this Lease or
Tenant's right to possession of the Premises is terminated or (b) Tenant assigns
any of its interest in this Lease or sublets any portion of the Premises,  other
than an assignment to an Affiliate.




                                     1 of 2

<PAGE>








               [DIAGRAM OF FIRST OFFER SPACE ON FIRST FLOOR PLAN]



































                                     2 of 2

<PAGE>


                                    EXHIBIT H


                                LETTER OF CREDIT




                                [BANK LETTERHEAD]


                                               , 1997


                 IRREVOCABLE, UNCONDITIONAL LETTER OF CREDIT NO.



Archon Group, L.P.
600 Las Colinas Boulevard, Suite 1900
Irving Texas 75039


Gentlemen:

     _________________________________, a national banking association ("Bank"),
of  ____________________________,  hereby issues its Irrevocable,  Unconditional
Letter of Credit in favor of WHC-Six  Real  Estate,  L.P.,  a  Delaware  limited
partnership,  and/or its successors and assigns  ("Landlord") for the account of
Palatin  Technologies,  Inc.,  a  Delaware  corporation,  ("Tenant")  up to  the
aggregate  amount of  $185,000,  available at sight by the drafts of Landlord on
the Bank.  Drafts drawn on this Letter of Credit will be honored when presented,
accompanied  only by a letter or  certificate  executed by a  representative  of
Landlord  stating that it is entitled to draw on this Letter of Credit under the
terms of the Lease Agreement,  dated as of ____________,  1997, between Landlord
and Tenant.  Partial draws shall be permitted  hereunder.  This Letter of Credit
may be assigned.

     The Bank  shall be  entitled  (and  required)  to rely upon the  statements
contained  in the  above-described  letter  or  certificate  and  will  have  no
obligation to verify the truth of any statements set forth therein.

     The Bank hereby  agrees with  drawers,  endorsers  and bona fide holders of
this Letter of Credit  that all drafts  drawn by reason of this Letter of Credit
and in  accordance  with the above  conditions,  will  meet with due honor  when
presented at the office of the Bank in ____________________.

     The obligations of the Bank shall not be subject to any claim or defense by
reason  of  the  invalidity,  illegality  or  inability  to  enforce  any of the
agreements set forth in the Lease.

<PAGE>



     This Letter of Credit is subject to the Uniform  Customs and  Practices for
Documentary  Credits  (1993  Revision)  fixed by the  International  Chamber  of
Commerce  (publication  400) when not in conflict with the express terms of this
Letter of Credit or with the  provisions  of Article 5,  N.J.S.A.  12A:5- 101 et
seq. of the New Jersey Uniform Commercial Code, as amended.

     This Letter of Credit shall terminate at 3:00 p.m. Eastern Daylight Savings
Time or Eastern  Standard Time, as  applicable,  on the first  anniversary  date
following the date hereof.

     Amounts  drawn upon this Letter of Credit are to be endorsed on the reverse
side of this Letter of Credit by the negotiating bank.

     THIS WRITTEN LOAN  AGREEMENT  REPRESENTS  THE FINAL  AGREEMENT  BETWEEN THE
PARTIES THAT MAY NOT BE  CONTRADICTED BY EVIDENCE OF PRIOR,  CONTEMPORANEOUS  OR
SUBSEQUENT  ORAL  AGREEMENTS  OF  THE  PARTIES.  THERE  ARE  NO  UNWRITTEN  ORAL
AGREEMENTS BETWEEN THE PARTIES.




                                      ---------------------------
                                      By:
                                         ------------------------
                                      Name:
                                           ----------------------
                                      Title:
                                            ---------------------



                     AMENDMENT TO EMPLOYMENT AGREEMENT
     
          This  Amendment  to that  certain  Employment  Agreement  dated  as of
November 16, 1995 (the "Employment  Agreement") between RhoMed  Incorporated,  a
Delaware corporation ("RhoMed"), and Edward J. Quilty, an individual residing at
1031 Creamery Rd., Newtown,  Pennsylvania 18940 (the  "Executive"),  is made and
entered into as of _____________,  1996, by and among RhoMed, the Executive, and
Palatin  Technologies,  Inc.,  a  Delaware  corporation  of  which  RhoMed  is a
wholly-owned subsidiary ("Palatin").

          WHEREAS,  Palatin  desires to employ the Executive,  and the Executive
desires to be  employed  by  Palatin,  on the same terms and  capacities  as are
contemplated in the Employment  Agreement,  by amending the Employment Agreement
to effect such employment, and whereas RhoMed has consented to such arrangement;

          WHEREAS, the Executive,  RhoMed and Palatin have determined that it is
in the best interest of the parties to this Amendment to clarify  certain of the
terms of the Employment Agreement.

          NOW,   THEREFORE,   in  consideration  of  the  mutual  covenants  and
agreements  contained  herein,  and intending to be legally  bound  hereby,  the
parties hereto hereby agree as follows:

          1. Effective as of _________,  1996, RhoMed will not be a party to the
Employment  Agreement  and the  Employment  Agreement  shall  from such time and
thereafter  be between  Palatin and the  Executive,  and all  references  in the
Employment Agreement to "RhoMed" shall be references to "Palatin."

          2.  The  merger  of  Palatin's  wholly-owned   subsidiary,   Interfilm
Acquisition  Corporation,  with and into RhoMed on June 25, 1996 (the  "Merger")
was not intended to and did not constitute a "change-in-control" under Paragraph
C of Article FIFTH of the Employment Agreement.

          Upon the execution hereof, each reference in the Employment  Agreement
to  "the  Employment  Agreement",  "this  Agreement",   "hereby",   "hereunder",
"herein", "hereof" or words of like import referring to the Employment Agreement
shall mean and refer to the Employment Agreement as amended by this Amendment to
the Employment Agreement.  All other provision of the Employment Agreement shall
remain in full force and effect  except  and to the  extent  explicitly  amended
hereby.

          This Amendment may be executed in any number of counterparts,  each of
which shall be an original and all of which  together  shall  constitute one and
the same Amendment.

<PAGE>

          IN WITNESS  WHEREOF,  the parties hereto have signed this Amendment or
caused this Amendment to be signed by their respective  officers  thereunto duly
authorized as of the date first written above.


PALATIN TECHNOLOGIES, INC.                    RHOMED INCORPORATED


     /s/ Edward J. Quilty                        /s/ John J. McDonough
By:-----------------------                    By:----------------------
Name: E. J. Quilty                            Name: John J. McDonough
Title: Chairman & CEO                         Title: VP & CFO


     /s/ Edward J. Quilty
By:-----------------------
     Edward J. Quilty


























                                       2


<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
COMPANY'S AUDITED CONSOLIDATED FINANCIAL STATEMENTS FOR THE FISCAL YEAR ENDED
JUNE 30, 1997 AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL
STATEMENTS
</LEGEND>

<MULTIPLIER>                                   1
<CURRENCY>                                     U.S. Dollars
       
<S>                             <C>
<PERIOD-TYPE>                   Year
<FISCAL-YEAR-END>                              JUN-30-1997
<PERIOD-START>                                 JUL-1-1996
<PERIOD-END>                                   JUN-30-1997
<EXCHANGE-RATE>                                1
<CASH>                                         12,806,717
<SECURITIES>                                   0
<RECEIVABLES>                                  84,562
<ALLOWANCES>                                   0
<INVENTORY>                                    0
<CURRENT-ASSETS>                               13,066,275
<PP&E>                                         1,159,145
<DEPRECIATION>                                 237,049
<TOTAL-ASSETS>                                 14,062,865
<CURRENT-LIABILITIES>                          2,738,727
<BONDS>                                        1,889,139
                          0
                                    1,378
<COMMON>                                       30,204
<OTHER-SE>                                     9,802,966
<TOTAL-LIABILITY-AND-EQUITY>                   14,062,865
<SALES>                                        22,184 
<TOTAL-REVENUES>                               722,357
<CGS>                                          0
<TOTAL-COSTS>                                  5,943,866
<OTHER-EXPENSES>                               0
<LOSS-PROVISION>                               0
<INTEREST-EXPENSE>                             374,664
<INCOME-PRETAX>                                0
<INCOME-TAX>                                   0
<INCOME-CONTINUING>                            5,300,164
<DISCONTINUED>                                 0
<EXTRAORDINARY>                                0
<CHANGES>                                      0
<NET-INCOME>                                   (5,300,164)
<EPS-PRIMARY>                                  (2.80)
<EPS-DILUTED>                                  (2.80)
        


</TABLE>


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