SYMBOLLON CORP
10QSB, 1996-11-06
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                    U.S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                  Form 10-QSB

(Mark One)
|X|      QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
         ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED SEPTEMBER 30, 1996
| |      TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES
         EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM ______ TO ________

Commission file number  0-22872
                       --------- 

                              SYMBOLLON CORPORATION
- -------------------------------------------------------------------------------
       (Exact name of small business issuer as specified in its charter)

            Delaware                            36-3463683
- -------------------------------            ------------------------
(State or other jurisdiction of              (I.R.S. Employer
incorporation or organization)              Identification No.)

                    122 Boston Post Road, Sudbury, MA 01776
- -------------------------------------------------------------------------------
                    (Address of principal executive offices)

                                  508-443-0165
- -------------------------------------------------------------------------------
                (Issuer's telephone number, including area code)


- -------------------------------------------------------------------------------
        (Former name, former address and former fiscal year, if changed
                               since last report)

Check whether the issuer (1) filed all reports required to be filed by Section
13 or 15(d) of the Exchange Act during the past 12 months (or for such shorter
period that the registrant was required to file such reports), and (2) has been
subject to such filing requirements for the past 90 days. Yes X  No

State the number of shares outstanding of each of the issuer's classes of common
equity, as of the latest practicable date.

                                    October 15, 1996
                                    -----------------
        Class A Common Stock            1,287,137
        Class B Common Stock            1,196,275

Transitional Small Business Disclosure Format (check one):

                    Yes             No    X
                        --------       --------

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                                    Page - 2


                             SYMBOLLON CORPORATION
                         (a development stage company)

                                     INDEX
                                    -------
                                                                           PAGE
PART I.  FINANCIAL INFORMATION

     Item 1.  Financial Statements

              Unaudited Condensed Balance Sheets
                    - September 30, 1996 and December 31, 1995               1

              Unaudited Condensed Statements of Operations
                    and Deficit Accumulated During the Development
                    Stage - For the nine and three months
                    ended September 30, 1996 and September 30, 1995          2

              Unaudited Condensed Statements of Cash Flows - For the nine
                    months ended September 30, 1996
                    and September 30, 1995                                   3

              Notes to the Unaudited Condensed Financial Statements          4

     Item 2.  Management's Discussion and Analysis
                     or Plan of Operation                                    5

PART II.  OTHER INFORMATION

     Item 5.  Other Information                                              7

     Item 6.  Exhibits and Reports on Form 8-K                               7

SIGNATURE                                                                    7

INDEX TO EXHIBITS                                                            8

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                                    Page - 3



                         Part I - Financial Information

Item 1 - Financial Statements
<TABLE>

                             SYMBOLLON CORPORATION
                         (a development stage company)

                            CONDENSED BALANCE SHEETS

                                     ASSETS
<CAPTION>
                                                                          September 30,     December 31,
                                                                              1996                1995
                                                                          -------------     ------------
Current assets:                                                            (unaudited)
<S>                                                                        <C>               <C>
  Cash and cash equivalents............................................... $ 1,908,683      $ 2,087,753
  Accounts receivable.....................................................      23,414           30,870
  Inventory...............................................................      30,415           31,279
  Prepaid expenses........................................................      30,346           80,554
                                                                           -----------      -----------
        Total current assets.............................................. $ 1,992,858      $ 2,230,456

Equipment and leasehold improvements, net of
 accumulated depreciation.................................................     134,560          159,990
Other assets:
    Patent and trademark cost, net of accumulated amortization............     123,169           90,099
Deposit...................................................................       5,000            5,000
                                                                          ------------      -----------
        TOTAL............................................................. $ 2,255,587      $ 2,485,545
                                                                          ============      ===========

                                   LIABILITIES
Current liabilities:
  Accounts payable........................................................ $    26,289      $    30,385
  Notes payable to stockholder............................................                       47,549
  Legal fees payable to related party.....................................      18,326            4,782
  Accrued Interest........................................................                       21,989
  Other accrued professional fees.........................................      20,894            3,822
  Other current liabilities...............................................      76,407           44,963
                                                                          ------------      ----------- 
        Total current liabilities.........................................     141,916          153,490

Accrued rent..............................................................      17,750           24,500
                                                                          ------------      -----------
        Total liabilities.................................................     159,666          177,990
                                                                          ------------      -----------

                               STOCKHOLDERS' EQUITY

Preferred stock, par value $.001 per share, 5,000,000 shares authorized
 Convertible Preferred Stock, Series A, $.001 par value, 444,444 shares
 issued at September 30, 1996 (liquidation preference $500,000)...........         444
Common stock, Class A, par value $.001 per share,
 18,750,000 shares authorized, 1,265,423 and 1,287,137 shares issued at
 December 31, 1995 and September 30, 1996, respectively...................       1,287            1,265
Common stock, Class B, par value $.001 per share,
 1,250,000 shares authorized,  1,214,713 and 1,196,275 shares issued at
 December 31, 1995 and September 30, 1996, respectively,
 each convertible into one share of Class A common stock..................       1,196            1,215
Additional paid-in capital................................................   7,238,843        6,732,739
Deficit accumulated during the development stage..........................  (5,145,849)      (4,427,664)
                                                                          ------------      -----------
     Total stockholders' equity...........................................   2,095,921        2,307,555
                                                                          ------------      -----------
                                                                                    
        TOTAL............................................................. $ 2,255,587       $ 2,485,545
                                                                          ============      ===========
</TABLE>

See notes to condensed financial statements.

                                        1



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                                    Page - 4

<TABLE>

                             SYMBOLLON CORPORATION
                          (a development stage company)

           CONDENSED STATEMENTS OF OPERATIONS AND DEFICIT ACCUMULATED
                          DURING THE DEVELOPMENT STAGE

<CAPTION>
                                                                                                               Period From
                                                                                                              July 15, 1986
                                                        Three Months Ended           Nine Months Ended       (Inception) to
                                                           September 30,               September 30,          September 30,
                                                         1996         1995           1996          1995           1996
                                                     -----------   -----------    -----------   -----------    -----------
                                                     (Unaudited)   (Unaudited)    (Unaudited)   (Unaudited)    (Unaudited)
<S>                                                  <C>           <C>            <C>           <C>            <C>
Net sales.........................................   $    33,509   $    23,319    $    50,241   $    81,578    $   173,222
License fee and contract revenue..................        51,529        87,500        634,116       162,500        999,116
                                                     -----------   -----------    -----------   -----------    -----------
        Total income..............................        85,038       110,819        684,357       244,078      1,172,338

Operating Expenses:
    Manufacturing costs...........................   $    22,665   $     4,959    $    36,179   $    84,929    $   139,779
    Research and development costs................       220,417       249,305        872,752       684,104      3,344,882
    General and administrative expenses...........       110,565       211,370        561,256       668,295      2,857,939
                                                     -----------   -----------    -----------   -----------    -----------
        Total operating expenses..................       353,647       465,634      1,470,187     1,437,328      6,342,600
                                                     -----------   -----------    -----------   -----------    -----------

Loss from operations..............................      (268,609)     (354,815)      (785,830)   (1,193,250)    (5,170,262)

Interest and other income.........................        23,543        35,982         69,715       112,233        364,449

Interest expense..................................          (410)         (839)        (2,070)       (2,490)      (340,036)
                                                     -----------   -----------    -----------   -----------    -----------

NET LOSS..........................................      (245,476)     (319,672)      (718,185)   (1,083,507)    (5,145,849)

Deficit accumulated during the development stage,
 beginning of period..............................    (4,900,373)   (3,817,788)    (4,427,664)   (3,053,953)
                                                     -----------   -----------    -----------   -----------    -----------
Deficit accumulated during the development stage,
 end of period....................................   $(5,145,849)  $(4,137,460)   $(5,145,849)  $(4,137,460)   $(5,145,849)
                                                     ===========   ===========    ===========   ===========    ===========

NET LOSS PER SHARE OF
 COMMON STOCK.....................................   $     (0.12)  $     (0.18)   $     (0.39)  $     (0.63)
                                                     ===========   ===========    ===========   ===========

Weighted average number of common
 shares outstanding...............................     2,015,296     1,757,047      1,859,095     1,719,225
                                                     ===========   ===========    ===========   ===========
</TABLE>

See notes to condensed financial statements.

                                       2

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<TABLE>
                             SYMBOLLON CORPORATION
                         (a development stage company)

                       CONDENSED STATEMENTS OF CASH FLOWS

<CAPTION>
                                                                                           Period From
                                                                                          July 15, 1986
                                                                Nine Months Ended        (Inception) to
                                                                  September 30,           September 30,
                                                                1996          1995           1996
                                                             -----------   -----------    -----------
                                                             (Unaudited)   (Unaudited)    (Unaudited)
<S>                                                          <C>           <C>            <C>
Cash flows from operating activities:
    Net loss..............................................   $  (718,185)  $(1,083,507)   $(5,145,849)
    Adjustments  to  reconcile  net  loss to net
    cash  provided  by  (used  in) operating activities:
      Depreciation and amortization expense...............        45,006        42,304        306,851
      Amortization of debt issuance costs.................                                    130,000
      Accrued rent........................................        (6,750)       (2,250)        17,750
      Changes in operating assets and liabilities:
        Accounts receivable...............................         7,456       (17,355)       (23,414)
        Inventory.........................................           864        46,200        (30,415)
        Prepaid expenses..................................        50,208        61,047        (30,346)
        Deferred revenue..................................                      25,000
        Accounts payable and other current liabilities....        35,975       (18,443)       141,916
                                                             -----------   -----------    -----------
        Net cash used in
        operating activities..............................      (585,426)     (947,004)    (4,633,507)
                                                             -----------   -----------    -----------
Cash flows from investing activities:
    Equipment and leasehold improvements costs............        (7,333)      (69,929)      (256,825)
    Patent and trademark costs............................       (45,314)      (22,319)      (307,756)
    Deposit...............................................                                     (5,000)
                                                             -----------   -----------    -----------
      Net cash used in investing activities...............       (52,647)      (92,248)      (569,581)
                                                             -----------   -----------    -----------
Cash flows from financing activities:
    Warrant conversion....................................                     629,204        629,204
    Borrowings from stockholders..........................         2,451                      256,074
    Repayment to stockholders.............................                                   (106,074)
    Sale of common stock and units........................         6,552                    7,225,969
    Sale of preferred stock...............................       450,000                      450,000
    Sale of option to purchase units......................                                        100
    Public offering costs.................................                                 (1,343,502)
                                                             -----------   -----------    -----------
      Net cash provided by
      financing activities................................       459,003       629,204      7,111,771
                                                             -----------   -----------    -----------
NET INCREASE (DECREASE) IN CASH...........................      (179,070)     (410,048)     1,908,683
Cash at beginning of period...............................     2,087,753     2,998,375
                                                             -----------   -----------    -----------
CASH AT END OF PERIOD.....................................   $ 1,908,683   $ 2,588,327    $ 1,908,683
                                                             ===========   ===========    ===========
</TABLE>

See notes to condensed financial statements.
 
                                      3



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                             SYMBOLLON CORPORATION
                         (a development stage company)

                    NOTES TO CONDENSED FINANCIAL STATEMENTS
                                  (Unaudited)

Note A - Description of Business:

         Symbollon Corporation (the "Company") was originally incorporated as an
Illinois  corporation  on July 15,  1986 as  Symbollon,  Inc.  On May 21,  1991,
Symbollon,   Inc.  was  merged  into  Symbollon  Corporation,   a  newly  formed
Massachusetts corporation (which was subsequently  reincorporated in Delaware in
August 1993),  to carry on the business of Symbollon Inc. Except where otherwise
indicated,  references to the Company in these  financial  statements  and notes
thereto include the activities of Symbollon, Inc.

         The  Company  was  formed  to  develop  and  commercialize  proprietary
enzyme-based  products for infection  control and  treatment in  biomedical  and
bioagricultural industries.

         The Company is in the development stage and its efforts since inception
have been principally  devoted to research and development,  securing patent and
trademark  protection and raising  capital.  In connection with its research and
development efforts, several grants under the Small Business Innovation Research
program  concerning  the Company's  technology  have been funded and  additional
grants are being pursued.  Management of the Company anticipates that additional
losses will be incurred as these efforts are pursued.

         In 1995,  the Company  signed a marketing and supply  agreement for its
first product and commenced shipping.

Note B - Accounting Policies and Disclosure:

         The accompanying  unaudited financial  statements do not contain all of
the disclosures required by generally accepted accounting  principles and should
be read in conjunction with the financial  statements and related notes included
in the Company's Form 10-KSB for the year ended December 31, 1995 filed with the
Securities and Exchange Commission.

         In the opinion of  management,  the  financial  statements  reflect all
adjustments,  all of which are of a normal recurring  nature,  to fairly present
the Company's  financial  position,  results of operations  and cash flows.  The
results of operations for the nine and  three-month  periods ended September 30,
1996 are not  necessarily  indicative of the results to be expected for the full
year.

Note C - Preferred Stock Issuance:

         During  the  third  quarter  of 1996 the  Company  completed  a private
placement of 444,444 shares of a new series of convertible  preferred stock at a
price of $1.125 per share.  The preferred  stock is convertible at any time into
an equal  number  of  shares of Class A Common  Stock,  and after one year,  the
conversion rate is subject to adjustment  based on the future price of the Class
A Common Stock. In exchange for the shares issued in the private placement,  the
Company  received  net cash  proceeds of  approximately  $450,000  and  canceled
$50,000 of principal and accrued interest on a demand promissory note.

                                       4

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                                    Page - 7


Item 2.  Management's Discussion and Analysis or Plan of Operation

MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS

         The Company is a  development  stage  company.  Since  inception of the
Company's  predecessor  in 1986,  the  Company's  efforts have been  principally
devoted to research and  development,  securing patent and trademark  protection
and raising capital,  most of which efforts commenced after May 1991. Except for
revenue  earned since 1995 on sales of IodoZyme,  the Company's  sole revenue to
date has been from research and  development  contracts with corporate  partners
and interest income.

Forward-Looking Statements

         Any  statements  set forth below or otherwise made in writing or orally
by the Company with regard to its expectations as to financial results and other
aspects of its business may  constitute  forward-looking  statements  within the
meaning of the Private  Securities  Litigation Reform Act of 1995.  Although the
Company  makes such  statements  based on  assumptions  which it  believes to be
reasonable, the Company's business is subject to significant risks and there can
be no  assurance  that  actual  results  will  not  differ  materially  from the
Company's expectations. Accordingly, the Company hereby identifies the following
important  factors,  among others,  which could cause its results to differ from
any results which might be projected,  forecasted or estimated by the Company in
any such forward-looking  statements:  (i) the timely development and acceptance
of new products,  (ii) the achievement of product development  milestones by the
Company's corporate partners,  (iii) the timely receipt of regulatory clearances
required to market the Company's proposed products,  and (iv) the continued sale
of IodoZyme, the Company's only product.

Results of Operations

         Symbollon's  net  loss  for the  three  and nine  month  periods  ended
September  30, 1996 were  $245,476  and  $718,185,  respectively,  reflecting  a
decrease of $74,196 (or 23.2%) and $365,322 (or 33.7%),  respectively,  from the
net loss in the comparable 1995 periods. The decrease for the three-month period
resulted  primarily  from decreased  general and  administrative  expenses.  The
decrease  for  the   nine-month   period   resulted   primarily  from  increased
license/contract  revenues  from a new  research  and  development  contract and
decreased  general and  administrative  expenses,  partially offset by increased
research  and  development  expenses.  The Company  expects to incur  additional
operating losses in the foreseeable future.

         Product  revenues  from sales of IodoZyme  for the three  month  period
ended  September  30, 1996 were  $33,509,  reflecting an increase of $10,190 (or
43.7%) from the product sales in the comparable  1995 period.  Product  revenues
from sales of IodoZyme for the nine month period ended  September  30, 1996 were
$50,241,  reflecting a decrease of $31,337 (or 38.4%) from the product  sales in
the comparable 1995 period.  IodoZyme sales remain below the  year-to-date  1996
sales  forecast,  and the  Company  has no reason to  believe  that  sales  will
materially increase during the remainder of 1996.

                                       5
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                                    Page - 8


         The gross  profit  margin on product  sales for the three month  period
ended  September 30, 1996 was 32.4%,  compared to 78.7% in the  comparable  1995
period. The gross profit margin on product sales for the nine month period ended
September 30, 1996 was 28%,  compared to (4.1)% in the  comparable  1995 period.
The  increase  in the gross  profit  margin on product  sales for the nine month
period ended September 30, 1996, from the comparable 1995 period,  was primarily
due to  resolution  of prior period  manufacturing  problems,  and reduced labor
costs  associated  with certain  manufacturing  activities now being  internally
performed,  partially  offset by  increased  per unit  overhead due to low sales
volume.

         General  and  administrative  expenses  for the  three  and nine  month
periods  ended  September  30, 1996 were  $110,565 and  $561,256,  respectively,
reflecting   a  decrease  of  $100,805   (or  47.7%)  and   $107,039  (or  16%),
respectively,  from the general and  administrative  expenses in the  comparable
1995  periods.  The  decreases  resulted  primarily  from  general  decreases in
salaries and other labor related costs,  and  professional  and other consulting
fees,  partially offset by increased  insurance costs.  Research and development
expenses  for the three month  period ended  September  30, 1996 were  $220,417,
reflecting  a decrease  of $28,888  (or 11.6%) in the  comparable  1995  period.
Research and development  expenses for the nine month period ended September 30,
1996 were  $872,752,  reflecting  an  increase  of  $188,648  (or  27.6%) in the
comparable  1995 period.  The increase for the nine month period ended September
30, 1996 resulted from increased  development  expenses,  including  third party
testing and  consultant  fees,  related to the  preparation of the 510(k) filing
with the Federal Food and Drug Administration (the "FDA") covering the Company's
high level  disinfectant  formulation.  The Company  filed the 510(k)  premarket
notification with the FDA on August 30, 1996.

Liquidity and Capital Resources

         The Company has funded its  activities  through  proceeds  from Class A
Warrant exercises,  its IPO and private placements of equity and debt securities
and  through  loans  from  principal  stockholders.   Independent  research  and
development  activities  regarding  the  Company's  technology  have been funded
through  SBIR  grants  received  and  administered  by  Biomedical   Development
Corporation.  As of  September  30,  1996,  the Company  had working  capital of
$1,850,942.

         The Company has had no significant  product  revenue and has incurred a
cumulative loss through September 30, 1996 of $5,145,849.  However,  the Company
believes that it has the necessary  liquidity  and capital  resources,  together
with anticipated  future revenues,  to sustain planned operations for the twelve
months  following  September 30, 1996. In the event that the Company's  internal
estimates  relating to its planned  revenues or  expenditures  prove  materially
inaccurate,  the Company may be required to  reallocate  funds among its planned
activities and curtail certain planned  expenditures.  In any event, the Company
anticipates that it will require additional funds after September 30, 1997.

                                       6

<PAGE>
                                    Page - 9


         During  the  remainder  of  1996,   the  Company   anticipates   paying
approximately  $70,000 as compensation for its current executive  officers,  and
approximately $12,750 for lease payments on its facilities. At December 31,1995,
the  Company  had a net  operating  loss  carryforward  for  Federal  income tax
purposes of approximately $4,125,000 expiring through 2010.

Part II - Other Information

Item 5.  Other Information

         In August of 1996, the Company completed a private placement of 444,444
shares of a new  series of  preferred  stock at a price of $1.125 per share (the
purchase  price was equal to the  average  market bid price of the common  stock
over the five days prior to closing). The purchasers consisted of two individual
investors,  one of which was Dr.  Kessler,  an executive  officer and  principal
stockholder  of the Company.  Of the total  444,444  shares,  44,444 shares were
purchased by Dr. Kessler in exchange for  cancellation  of principal and accrued
interest on a demand  promissory note. The preferred stock is convertible at any
time into an equal  number of  shares of Class A Common  Stock.  After one year,
however,  if the price of the common stock is below $1.125,  the conversion rate
will be  adjusted  to  increase  the  amount  of  common  stock  issuable  by an
approximate  20%  premium  over a pro rata  adjustment  for the decline in stock
price.  Purchasers  in the private  placement  were granted  certain  demand and
piggyback registration rights with respect to the underlying stock. The net cash
proceeds from this private  placement  (approximately  $450,000) will be used to
fund the Company's ongoing development efforts.

Item 6. Exhibits and Reports on Form 8-K

         (a)      Exhibits

                  See Index to Exhibits on Page E-1.

         (b)      Reports on Form 8-K

                  No reports on Form 8-K were filed during the quarter for which
this report is filed.

                                   SIGNATURES

         In accordance with the requirements of the Exchange Act, the registrant
caused this report to be signed on its behalf of the undersigned, thereunto duly
authorized.

                                    SYMBOLLON CORPORATION

Date:  November 4, 1996             By: /S/ Paul C. Desjourdy
                                        ---------------------
                                        Paul C. Desjourdy, Vice President/CFO
                                        and authorized signatory

                                       7

<PAGE>
                                   Page - 10


                             SYMBOLLON CORPORATION

                               INDEX TO EXHIBITS

                                                                          Page #

3.1      Certificate of Incorporation, including Certificate of
         Designations, Preferences and Rights of Series A Preferred Stock
         of the Company...................................................

10.16    Stock Purchase Agreement, dated August 14, 1996, among the
         Company, Anthony J. Cantone and Jack H. Kessler..................

11.1     Statement re: Computation of Earnings per Share..................

27.1     Financial Data Schedule..........................................


                                       8





<PAGE>
                                    Page - 1


                                                                     Exhibit 3.1

                          CERTIFICATE OF INCORPORATION

                                       OF

                              SYMBOLLON CORPORATION

         FIRST:   The  name  of  the  corporation  is  SYMBOLLON  CORPORATION
(hereinafter  referred  to  as  the "Corporation").

         SECOND: The address of the Corporation's registered office in the State
of Delaware is 32 Loockerman Square, Suite L-100, City of Dover, County of Kent,
19901.  The name of the  registered  agent at such address is The  Prentice-Hall
Corporation System, Inc.

         THIRD:   The  purpose  of  the  Corporation  is to  engage  in  any
lawful act or activity for which corporations may be organized under the
Delaware General Corporation Law.

         FOURTH:  I. The  aggregate  number of shares  which  the  Corporation
shall  have  authority  to issue is Twenty Five  Million  (25,000,000)  shares,
consisting  of (i) Eighteen Million Seven Hundred Fifty Thousand (18,750,000)
shares of Class A Common Stock, par value $.001 per share ("Class A Common
Stock"), (ii) One Million Two Hundred Fifty Thousand (1,250,000) shares of Class
B Common Stock, par value $.001 per share ("Class B Common Stock"), and (iii)
Five Million (5,000,000) shares of Preferred  Stock, par value $.001 per share
("Preferred Stock").

                 II. Except as otherwise  provided in this Article  FOURTH,  the
rights,  preferences  and limitations of Class A Common Stock and Class B Common
Stock shall be identical in all respects:

                 (a) The  dividend  rights of the  holders  of shares of Class A
Common Stock and Class B Common Stock shall be  identical,  except that no stock
dividends on the Class A Common Stock may be paid in Class B Common Stock and no
stock dividends on the Class B Common Stock may be paid in Class A Common Stock.
Whenever a stock  dividend is paid, the holder of a share of any class of common
stock shall be paid in the same number of shares of common stock of the class of
such  shares as are paid to the  holder of a share of common  stock of any other
class in shares of common stock of such other class.  Whenever a combination  or
subdivision  of the  shares  of any  class of  common  stock  is made,  the same
combination  or  subdivision  shall be made with respect to the other classes of
common stock.

                 (b) Each share of Class A Common Stock shall entitle the holder
to one vote and each share of Class B Common

                                       1
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                                    Page - 2


Stock shall entitle the holder to five votes on all matters with respect to
which holders of such classes of stock are entitled to vote.

                 (c) (i) All outstanding shares of Class B Common Stock shall be
convertible at all times, at the election of the holder  thereof,  into an equal
number  of  fully  paid and  nonassessable  shares  of  Class A Common  Stock by
delivery of written  notice by the holder of such shares of Class B Common Stock
to the  Corporation,  or its transfer agent,  of his election  together with the
certificate(s)   representing  the  shares  to  be  converted.   Thereupon,  the
Corporation,  or its transfer  agent,  as the case may be, shall  exchange  such
certificate(s) for a certificate or certificates representing an equal number of
shares of Class A Common  Stock.  Shares of Class B Common Stock shall be deemed
to have been  converted  immediately  prior to the close of  business on the day
upon which the  Corporation,  or its transfer  agent,  receives  such shares for
conversion.  The person  entitled to receive the Class A Common  Stock  issuable
upon such  conversion  shall be treated for all purposes as the record holder of
such Class A Common Stock at such time.

                     (ii)  Except as provided in subparagraph (iii) below, upon
the  sale,  assignment,  transfer,  conveyance,  or other  disposition,  whether
voluntary,  by  operation  of law or otherwise  (a  "Transfer",  which,  for the
purpose  hereof,  shall not include a pledge) of shares of Class B Common Stock,
other than a transfer to another  holder of Class B Common Stock or to a private
charitable  foundation  as to which a holder of Class B Common Stock is the sole
voting  member,  the shares so  transferred  shall,  by virtue of such Transfer,
automatically be converted into an equal number of fully paid and  nonassessable
shares of Class A Common Stock.

                    (iii) Upon the death of any holder of Class B Common  Stock,
the  shares  of  Class B  Common  Stock  so held as of the  date of death of the
deceased  stockholder  shall be automatically  converted into an equal number of
fully paid and  nonassessable  shares of Class A Common  Stock unless and to the
extent that any of such shares are purchased by another holder of Class B Common
Stock on or prior to 90 days from the date that a legal  representative  is duly
appointed  by a court of competent  jurisdiction,  or 120 days from such date if
within such 90 day period  another  holder of Class B Common Stock has exercised
any  right  to  purchase  shares  of  Class B Common  Stock  held by such  legal
representative.  If there  should be only one  holder  of Class B Common  Stock,
effective immediately upon his death, the shares of Class B Common Stock so held
as of the date of death shall be automatically converted into an equal number of
fully paid and nonassessable shares of Class A Common Stock.

                                       2
<PAGE>
                                    Page - 3


                   (iv)  With  respect  to any  shares  of Class B Common  Stock
converted into Class A Common Stock  pursuant to paragraphs  (i), (ii) and (iii)
above, until surrender as hereinafter  provided,  each outstanding  certificate,
which prior to such conversion represented shares of Class B Common Stock, shall
be deemed for all  purposes  to  evidence  ownership  of the number of shares of
Class A Common  Stock into which the shares of Class B Common  Stock  shall have
been converted.  Upon surrender to the  Corporation,  or its transfer agent, for
cancellation of the certificate or certificates  representing  such shares,  the
holder  thereof  shall be  entitled  to receive a  certificate  or  certificates
representing  the  number  of shares of  Common  Stock to which  such  holder is
entitled.

                   (v) With  respect  to any  shares  of  Class B  Common  Stock
converted  into Class A Common Stock  pursuant to paragraphs  (i), (ii) or (iii)
above,  such converted shares of Class B Common Stock shall,  from and after the
date of conversion, have the status of authorized and unissued shares of Class B
Common Stock and may be reissued as shares of Class B Common Stock.

                 III. The Board of Directors of the  Corporation  is authorized,
subject to  limitations  prescribed  by law and the  provisions  of this Article
FOURTH,  to provide for, from time to time, in one or more series of any number,
the issuance of shares of Preferred Stock, and, by filing a certificate pursuant
to the General Corporation Law of the State of Delaware, to establish the number
of  shares  to be  included  in each  such  series  and to fix the  designation,
relative rights,  preferences,  qualifications  and limitations of the shares of
each such  series.  The  authority of the Board  Directors  with respect to each
series  shall  include,  but not be  limited  to,  determination  of each of the
following:

                   A. The number of shares constituting that series and the
distinctive designation of that series;

                   B. The  dividend  rate on the shares of the  series,  whether
dividends shall be cumulative and, if so, from which date or dates,  and whether
they shall be payable in preference to, or in another relation to, the dividends
payable on any other class or classes or series of stock;

                   C. Whether that series shall have voting rights, in addition
to the voting rights provided by law, and, if so, the terms of such voting
rights;

                   D. Whether that series shall have conversion or exchange
privileges, and, if so, the terms and

                                       3
<PAGE>
                                    Page - 4


conditions of such conversion or exchange, including provision for  adjustment
of the conversion or exchange rate in such events as the Board of Directors
shall determine;


                   E.  Whether  or not  the  shares  of  that  series  shall  be
redeemable,  and if so, the terms and conditions of such  redemption,  including
the manner of selecting  shares for  redemption if less than all such shares are
to be redeemed,  the date or dates upon or after which they shall be redeemable,
and the amount per share  payable in case of  redemption,  which amount may vary
under different conditions and at different redemption dates;

                   F. Whether  that series shall be entitled to the benefit of a
sinking fund to be applied to the purchase or redemption of shares of that
series and, if so, the terms and amounts of such sinking fund;

                   G. The right of the  shares of the  series to the  benefit of
conditions and restrictions upon the creation of indebtedness of the Corporation
or any subsidiary,  upon the issue of any additional stock (including additional
shares of such series or of any other  series) and upon the payment of dividends
or the making of other  distributions  on and the purchase,  redemption or other
acquisition by the  Corporation or any subsidiary of, any  outstanding  stock of
the Corporation;

                   H. The right of the shares of that series in the event of any
voluntary  or  involuntary  liquidation,   dissolution  or  winding  up  of  the
Corporation,  and whether  such rights shall be in  preference  to or in another
relation  to the  comparable  rights of any other  class or classes or series of
stock; and

                   I. Any other relative, participating optional or other
special,  rights, qualifications, limitations or restrictions of that series.

                 IV.  Shares of any series of  Preferred  Stock  which have been
redeemed  (whether  through the  operation  of a sinking fund or  otherwise)  or
which, if convertible or exchangeable, have been converted into or exchanged for
shares  of stock of any  other  class  or  classes,  shall  have the  status  of
authorized and unissued  shares of Preferred Stock of the same series and may be
reissued  as part of the series of which they were  originally  a part or may be
reclassified and reissued as part of any other series of Preferred Stock or of a
new series of Preferred  Stock to be created by resolution or resolutions of the
Board of Directors, all subject to the conditions and the restrictions on

                                       4
<PAGE>
                                    Page - 5


issuance  set forth in the  resolution  or  resolutions  adopted by the Board of
Directors providing for the issue of any series of Preferred Stock.

                  V.  Except  as  otherwise   provided  by  the   resolution  or
resolutions  providing  for the issue of any series of  Preferred  Stock,  after
payment  shall  have been made to the  holders  of  Preferred  Stock of the full
amount of dividends to which they shall be entitled  pursuant to the  resolution
or resolutions  providing for the issuance of any series of preferred Stock, the
holders of Class A and Class B Common Stock shall be entitled,  to the exclusion
of the  holders  of  Preferred  Stock of any and all  series,  to  receive  such
dividends as from time to time may be declared by the Board of Directors.

                  VI.  Except  as  otherwise   provided  by  the  resolution  or
resolutions  providing  for the issue of any series of Preferred  Stock,  in the
event of any liquidation,  dissolution of winding up of the Corporation, whether
voluntary or involuntary,  the holders of Class A and Class B Common Stock shall
be  entitled,  after  payment  shall have been made to the holders of  Preferred
Stock of the full  amount  to which  they  shall  be  entitled  pursuant  to the
resolution or resolutions  providing for the issuance of any series of Preferred
Stock,  to share,  to the exclusion of the holders of Preferred Stock of any and
all  series,   in  all  remaining  assets  of  the  Corporation   available  for
distribution to its  stockholders  ratably  according to the number of shares of
Class A and Class B Common Stock held by them.

                 VII.  The  number of  authorized  shares of any class may be
increased or decreased by the affirmative vote of the holders of a majority of
the stock of the Corporation entitled to vote.

         FIFTH: The name and mailing address of the sole incorporator are as
follows:

                            Veronica Andrews Goldberg
                           Rubin Baum Levin Constant & Friedman
                         30 Rockfeller Plaza, 29th Floor
                             New York New York 11012

         SIXTH:  The number of directors which shall constitute the entire Board
of Directors of the Corporation  shall be not less than three,  the exact number
to be fixed from time to time by the Board of Directors pursuant to a resolution
duly  adopted by a majority  of the entire  Board.  Except as may  otherwise  be
required  by  law,  vacancies  in the  Board  of  Directors  and  newly  created
directorships  resulting from any increase in the authorized number of directors
may be filled by a majority of the directors then in office,  though less than a
quorum.

                                       5
<PAGE>
                                    Page - 6


         SEVENTH:  No directors of the Corporation shall be personally liable to
the Corporation or its stockholders for monetary damages for breach of fiduciary
duty as a director,  provided  that this Article  SEVENTH shall not eliminate or
limit the liability of a director (i) for any breach of such  director's duty of
loyalty to the  Corporation or its  stockholders,  (ii) for acts or omissions of
such  director  not in good faith or which  involve  intentional  misconduct  or
knowing  violation  of law,  (iii)  under  Section 174 of the  Delaware  General
Corporation Law, or (iv) for any transaction from which such director derived an
improper personal benefit; nor shall this Article SEVENTH eliminate or limit the
liability of a director for any act or omission occurring prior to the date this
Article SEVENTH becomes effective.

         EIGHTH:  The Board of Directors is expressly authorized to adopt, amend
and repeal the By-Laws of the Corporation.

         NINETH:  The  Corporation  shall,  to the fullest  extent  permitted by
Section 145 of the Delaware  General  Corporation Law as the same may be amended
or  supplemented,  indemnify  any and all  persons  whom it shall  have power to
indemnify from and against any and all expenses, liabilities or other matters.

         TENTH:  Whenever a compromise or arrangement  is proposed  between this
Corporation  and  its  creditors  or any  class  of  them  and/or  between  this
Corporation  and its  stockholders  or any class of them, any court of equitable
jurisdiction  within the State of Delaware may, on the  application in a summary
way of this  Corporation  or of any  creditor or  stockholder  thereof or on the
application of any receiver or receivers  appointed for this  Corporation  under
the  provisions  of  Section  291 of  Title  8 of the  Delaware  Code  or on the
application of trustees in dissolution or of any receiver or receivers appointed
for this  Corporation  under the  provisions  of  Section  279 of Title 8 of the
Delaware Code order a meeting of the creditors or class of creditors,  and/or of
the stockholders or class of stockholders of this  Corporation,  as the case may
be, to be summoned in such  manner as the said court  directs.  If a majority in
number  representing  three-fourths  in  value  of the  creditors  or  class  of
creditors,  and/or  of  the  stockholders  or  class  of  stockholders  of  this
Corporation,  as the case may be, agree to any compromise or arrangement  and to
any  reorganization  of this  Corporation as a consequence of such compromise or
arrangement,  the said  compromise of  arrangement  and the said  reorganization
shall,  if sanctioned by the court to which the said  application has been made,
be  binding  on all the  creditors  or class  of  creditors,  and/or  on all the
stockholders or class of stockholders,  of this Corporation, as the case may be,
and also on this Corporation.

                                       6
<PAGE>
                                    Page - 7


         I, THE UNDERSIGNED, being the sole incorporator hereinbefore named, for
the purpose of forming a corporation  pursuant to the General Corporation Law of
the State of Delaware,  do make this certificate,  declaring and certifying that
this is my act and deed and the facts herein  stated are true,  and  accordingly
have hereunto set my hand this 29th day of July, 1993.


                                    /S/ Veronica Andrews Goldberg
                                    ---------------------------------------
                                    Veronica Andrews Goldberg, Incorporator

                                       7




<PAGE>
                                    Page - 8


                    CERTIFICATE OF DESIGNATIONS, PREFERENCES

                     AND RIGHTS OF SERIES A PREFERRED STOCK

                                       OF

                              SYMBOLLON CORPORATION

The undersigned officers of Symbollon  Corporation,  a corporation organized and
existing under the General  Corporation Law of the State of Delaware,  do hereby
certify  that,   pursuant  to  authority   conferred  by  the   Certificate   of
Incorporation,  and  pursuant  to the  provisions  of Section 151 of the General
Corporation  Law of the State of  Delaware,  the Board of Directors of Symbollon
Corporation  at a meeting duly  authorized  and validly held on August 13, 1996,
adopted  a  resolution  providing  for  certain  powers,  designations,  number,
preferences  and  relative,  participating,  optional or other  rights,  and the
qualifications, limitations or restrictions thereof, of 444,444 shares of Series
A Preferred Stock, $.001 par value, which resolution is as follows:

         RESOLVED:  That  pursuant  to  Article  Fourth  of the  Certificate  of
         Incorporation  of this  Corporation,  the  Board  of  Directors  hereby
         establishes  a series  of  Preferred  Stock,  $.001 par  value,  of the
         Corporation   having  the  following  powers,   designations,   number,
         preferences  and relative,  participating,  option of or others special
         rights, and qualifications, limitations or restrictions thereof:

                Description and Designation of Series A Preferred Stock

         1.  Designation.  A  total  of  444,444  shares  of  the  Corporation's
Preferred  Stock shall be  designated  the "Series A Preferred  Stock".  As used
herein,  the  term  "Preferred  Stock"  used  without  reference  to  any  other
outstanding  series of Preferred  Stock of the  Corporation as from time to time
may be  outstanding  means  all such  outstanding  series  of the  Corporation's
Preferred  Stock,  share for share alike and without  distinction  as to series,
except as otherwise  expressly  provided for herein, or as the context otherwise
requires.

         2.  Dividends.

                  (a)  Computation of Cumulative  Dividends.  The holders of the
outstanding shares of Series A Preferred Stock shall be entitled to receive, out
of funds legally available therefor,  cumulative dividends at the annual rate of
$0.09 per share.  Cumulative  dividends on the Series A Preferred Stock shall be
payable if, as and when declared.

                  Dividends  on the Series A Preferred  Stock shall  accrue from
day to day on each share of Series A  Preferred  Stock from the date of original
issuance  of such share,  whether or not earned or  declared,  and shall  accrue
until paid.

                                       1
<PAGE>
                                    Page - 9


                  All numbers  relating to calculation  of cumulative  dividends
shall be subject to  equitable  adjustment  in the event of any stock  dividend,
stock split, combination, reorganization, recapitalization,  reclassification or
other similar event involving a change in the capital  structure of the Series A
Preferred  Stock.  Such  dividends  on the  Series A  Preferred  Stock  shall be
cumulative  so that if such  dividends  in  respect of any  previous  or current
annual dividend period, at the annual rate specified above,  shall not have been
paid or declared and a sum  sufficient  for the payment  thereof set apart,  the
deficiency  shall first be fully paid before any dividend or other  distribution
shall be paid or declared and set apart for the Class A Common Stock and Class B
Common Stock  (collectively,  the "Common  Stock").  Upon any  conversion of the
Series A Preferred  Stock under  Section 5 hereof,  all such  accrued and unpaid
dividends  on the  Series  A  Preferred  Stock  to and  until  the  date of such
conversion shall be forfeited and shall not be due and payable.

                  (b) Restriction on Distributions.  Except to the extent in any
instance  approval  is  provided  in writing by the holders of a majority of the
outstanding  shares of Preferred  Stock (all series acting  together as a class)
and except for any transaction  related to the Corporation's Class A Warrants or
Class B Warrants,  the  Corporation  shall not declare or pay any dividends,  or
purchase,  redeem,  retire,  or  otherwise  acquire  for value any shares of its
capital  stock (or rights,  options or warrants to purchase  such shares) now or
hereafter  outstanding,  return any capital to its stockholders as such, or make
any distributions of assets to its stockholders as such;  provided,  however, if
any such action is effected  with respect to the  Preferred  Stock,  it shall be
done  proportionately  equivalent  for the holders of all series of  outstanding
Preferred Stock.

                  Nothing herein  contained shall prevent the Corporation  from:
(i)  effecting a stock split or declaring or paying any dividend  consisting  of
shares of any class of capital stock paid to the holders of shares of such class
of capital stock; or (ii) complying with any specific  provision of the terms of
the Preferred Stock.

                  (c)  Participating  Dividends.  In the event that the Board of
Directors  of the  Corporation  shall  declare a dividend  payable upon the then
outstanding  shares of Common Stock  (other than a stock  dividend on the Common
Stock distributed  solely in the form of additional shares of Common Stock), the
holders of the Preferred Stock shall be entitled,  in addition to any cumulative
dividends to which they may be entitled under Section 2(a) hereof, to the amount
of dividends  per share of Preferred  Stock as would be declared  payable on the
largest  number  of whole  shares of  Common  Stock  into  which  each  share of
Preferred  Stock held by each holder thereof could be converted  pursuant to the
provisions of Section 5 hereof, such number determined as of the record date for
the  determination of holders of Common Stock entitled to receive such dividend,
less any dividends theretofore paid under Section 2(a) above.

                                       2
<PAGE>
                                    Page - 10


         3.       Liquidation, Dissolution or Winding Up.

                  (a) Treatment at  Liquidation,  Dissolution  or Winding Up. In
the event of any  liquidation,  dissolution  or winding  up of the  Corporation,
whether voluntary or involuntary, or in the event of its insolvency,  before any
distribution  or  payment is made to any  holders  of Common  Stock or any other
class or series of capital stock of the  Corporation  designated to be junior to
the Preferred  Stock,  and subject to the liquidation  rights and preferences of
any class or series of Preferred Stock designated in the future to be senior to,
or on a parity with,  the Series A Preferred  Stock with respect to  liquidation
preferences,  the holders of each share of Preferred  Stock shall be entitled to
be paid first out of the assets of the Corporation available for distribution to
holders of the Corporation's  capital stock of all classes,  whether such assets
are capital, surplus or earnings, an amount equal to the greater of:

                           (i)  $1.125  per share of Series A  Preferred  Stock,
                  plus all  accrued  but unpaid  cumulative  dividends  thereon,
                  whether or not earned or declared, or

                           (ii)  such  amount  per share of  Preferred  Stock as
                  would have been  payable had each such share of each series of
                  Preferred  Stock been  converted to Common  Stock  immediately
                  prior to such event of liquidation,  dissolution or winding up
                  pursuant to the provisions of Section 5 hereof.

                  The  amounts  set forth  above  shall be subject to  equitable
adjustment   whenever  there  shall  occur  a  stock   dividend,   stock  split,
combination, reorganization, recapitalization, reclassification or other similar
event involving a change in the capital structure of the Preferred Stock.

                  If,  upon  liquidation,  dissolution  or  winding  up  of  the
Corporation,  the assets of the  Corporation  available for  distribution to its
stockholders  shall be insufficient to pay the holders of all outstanding series
of Preferred  Stock the full amounts to which they otherwise  would be entitled,
the holders of all  outstanding  series of Preferred  Stock (which is deemed for
purposes  of this  Section  3 to be on a  parity)  shall  share  ratably  in any
distribution  of  available  assets  pro rata in  proportion  to the  respective
liquidation preference amounts which would otherwise be payable upon liquidation
with respect to the  outstanding  shares of Preferred  Stock if all  liquidation
preference  dollar amounts with respect to such shares were paid in full,  based
upon the aggregate liquidation preference dollar amounts payable upon all shares
of Preferred Stock then outstanding (the "Liquidation Formula").

                                       3
<PAGE>
                                    Page - 11


                  After such payment shall have been made in full to the holders
of the Preferred  Stock, or funds necessary for such payment shall have been set
aside by the  Corporation  in trust for the account of holders of the  Preferred
Stock so as to be available for such payment, the remaining assets available for
distribution shall be distributed ratably among the holders of the Common Stock.

                  (b) Distributions  Other than Cash.  Whenever the distribution
provided for in this Section shall be payable in property  other than cash,  the
value of such  distribution  shall be the fair market value of such  property as
determined  in good  faith by the Board of  Directors  of the  Corporation.  All
distributions  (including distributions other than cash) made hereunder shall be
made  pro  rata to each  series  of  Preferred  Stock  in  accordance  with  the
Liquidation Formula described in Section 3(a) above. In the event of any dispute
between the holders of the  Preferred  Stock and the  Corporation  regarding the
determination  of the  fair  market  value  of  non-cash  distributions,  at the
election  of the holders of a majority of the  outstanding  shares of  Preferred
Stock,  the  Corporation  shall engage a consulting or  investment  banking firm
selected by the Board of Directors  and approved by the holders of a majority of
the outstanding shares of Preferred Stock to prepare an independent appraisal of
the  fair  market  value  of  such  property  to be  distributed.  Each  of  the
Corporation and the holders of a majority of the outstanding shares of Preferred
Stock shall provide such approved  appraiser with a written estimate of the fair
market  value of such  property,  and the  expenses of any  appraisal  by such a
consulting  or  investment  banking  firm shall be borne by the party  whose own
written  estimate of fair market value  proves to be furthest  from that of such
consulting or investment  banking firm. In the event that the parties' estimates
of fair market value differ from that of the  consulting or  investment  banking
firm by an equal amount, then the Corporation,  on the one hand, and the holders
of the Preferred Stock, on the other, shall each pay fifty percent (50%) of such
expenses.

         4.       Voting Power

         Except as otherwise  expressly  provided in this Section 4 or Section 6
hereof or as otherwise  required by law, each holder of Series A Preferred Stock
shall be entitled to vote on all matters and shall be entitled to that number of
votes equal to the  largest  number of whole  shares of Common  Stock into which
such holder's shares of Series A Preferred Stock could be converted, pursuant to
the provisions of Section 5 hereof,  at the record date for the determination of
stockholders  entitled  to vote on such  matter  or, if no such  record  date is
established,  at the  date  such  vote  is  taken  or  any  written  consent  of
stockholders  is  solicited.  Except as  otherwise  expressly  provided  in this
instruments,  the  Certificate of  Designations,  Preferences  and Rights of any
other series of outstanding Preferred Stock or as otherwise required by law, the
holders of shares of Preferred  Stock and Common  Stock shall vote  together (or
render  written  consents  in lieu of a vote) as a single  class on all  matters
submitted to the stockholders of the Corporation.

                                       4
<PAGE>
                                    Page - 12


         5.       Conversion  Rights.  The holders of the Series A Preferred
Stock shall have the following rights with respect to the conversion of such
shares into shares of Class A Common Stock:

                  (a) General.  Subject to and in compliance with the provisions
of this Section 5, any shares of the Series A Preferred Stock may, at the option
of any holder,  be converted  at any time and from time to time into  fully-paid
and non-assessable shares of Class A Common Stock. The number of shares of Class
A Common  Stock which a holder of Series A Preferred  Stock shall be entitled to
receive  upon  conversion  shall be the  product  obtained  by  multiplying  the
Applicable  Conversion  Rate  (determined  as provided  in Section  5(b)) by the
number of shares of Series A Preferred Stock being converted at any time.

                  (b) Applicable  Conversion Rate. The conversion rate in effect
at any time for the Series A Preferred Stock (the "Applicable  Conversion Rate")
shall be the  quotient  obtained by dividing  $1.125 by the Series A  Applicable
Conversion  Value,  calculated  as  provided  in  Section  5(c)  (the  "Series A
Applicable Conversion Rate").

                  (c)  Applicable  Conversion  Value.  The  Series A  Applicable
Conversion  Value in effect from time to time,  except as adjusted in accordance
with Section 5(d) hereof, shall be $1.125 with respect to the Series A Preferred
Stock (the "Series A Applicable Conversion Value").

                  (d)  Adjustments to Series A Applicable Conversion Value.

                      (i) Closing Bid Price.  At any time after August 14, 1997,
if at the time of  conversion  the  average  Closing  Bid Price (as  hereinafter
defined)  of the Class A Common  Stock of the  Corporation  for the  immediately
preceding  twenty (20) consecutive  trading days (the  "Twenty-Day  Average") is
below the Series A Applicable Conversion Value then in effect, then the Series A
Applicable  Conversion  Value relevant only for the shares of Series A Preferred
Stock being then converted shall automatically be adjusted  immediately prior to
conversion to equal 83.33% of the Twenty-Day Average.  The preceding  adjustment
to the Series A Applicable  Conversion  Value  relevant to the shares being then
converted  shall  not  adjust  or  otherwise  effect  the  Series  A  Applicable
Conversion  Value of the  remaining  outstanding  shares of  Series A  Preferred
Stock.

                  The  "Closing  Bid Price" shall mean (1) if the Class A Common
Stock is then listed on any  national  securities  exchange,  the closing  sales
price on the principal  national  securities  exchange on which it is so traded,
(2) if the Class A Common  Stock is not then  listed on any such  exchange,  the
closing  bid  price on the  over-the-counter  market  as  reported  by  NASDAQ's
National Market System or Small Capitalization System ("NASDAQ"),  or (3) if the
Class A Common  Stock is not then  listed  on any such  exchange  or  quoted  in
NASDAQ, the average of the closing bids on the National Daily Quotation Service.
If for any trading day the Class A Common Stock is listed on any

                                       5
<PAGE>
                                    Page - 13


such  exchange, or quoted in NASDAQ or National Daily Quotation Service and the
actual Closing Bid  Price is not determinable in accordance with the above, then
for such trading day the Closing Bid Price shall be the last immediately
reported Closing Bid Price.  If the Class A Common Stock is not listed on any
such  exchange, or quoted in NASDAQ or National Daily Quotation Service, the
Closing Bid Price shall be determined in good faith by the Board of Directors of
the Corporation.

                      (ii) Upon Extraordinary Common Stock Event.  Upon the
happening of an Extraordinary Common Stock Event (as hereinafter  defined),  the
Series A Applicable Conversion Value shall, simultaneously with the happening of
such  Extraordinary  Common Stock Event, be adjusted by multiplying the Series A
Applicable  Conversion Value by a fraction,  the numerator of which shall be the
number  of  shares  of  Common  Stock  outstanding  immediately  prior  to  such
Extraordinary  Common  Stock  Event and the  denominator  of which  shall be the
number  of  shares  of  Common   Stock   outstanding   immediately   after  such
Extraordinary  Common Stock Event,  and the product so obtained shall thereafter
be the Series A Applicable  Conversion Value. The Series A Applicable Conversion
Value, as so adjusted, shall be readjusted in the same manner upon the happening
of any successive Extraordinary Common Stock Event or Events.

                  An "Extraordinary Common Stock Event" shall mean (I) the issue
of  additional  shares of Common  Stock as a dividend or other  distribution  on
outstanding  shares of Common Stock, (ii) a subdivision of outstanding shares of
Common  Stock  into a greater  number of  shares  of  Common  Stock,  or (iii) a
combination or reverse stock split of outstanding  shares of Common Stock into a
smaller number of shares of the Common Stock.

                  (e)      Automatic Conversion.

                      (i) Mandatory Conversion of Preferred  Stock.  Immediately
upon  (1)  the  effectiveness  of an  underwritten  public  offering  on a  firm
commitment basis pursuant to an effective  registration statement filed pursuant
to the Securities Act of 1933, as amended, covering the offer and sale of Common
Stock for the  account  of the  Corporation  in which the  Corporation  actually
receives gross proceeds equal to or greater than  $5,000,000  (calculated  after
deducting  underwriters'  discounts and  commissions  but before  calculation of
expenses),  and in which the price per share of Common  Stock  equals or exceeds
$3.00  (such price  subject to  equitable  adjustment  in the event of any stock
dividend,   stock   split,   combination,   reorganization,    recapitalization,
reclassification or other similar event involving a change in the Common Stock),
(2) the  approval,  set forth in a written  notice  to the  Corporation,  of the
holders of at least a majority of the  outstanding  shares of Series A Preferred
Stock of an  election to convert  Series A  Preferred  Stock into Class A Common
Stock, or (3) August 14, 2001, then all outstanding shares of Series A Preferred
Stock  shall be  converted  automatically  into the  number of shares of Class A
Common  Stock  into  which  such  shares  of Series A  Preferred  Stock are then
convertible pursuant to Section 5

                                       6
<PAGE>
                                    Page - 14


hereof as of the closing and consummation of such underwritten  public offering,
the stated date of approval of such holders of Series A Preferred Stock or
August 14, 2001,  without any further  action by the holders of such shares and
whether or not the certificates representing such shares are surrendered to the
Corporation or its transfer agent.

                      (ii) Surrender of Certificates Upon Mandatory  Conversion.
Upon  the  occurrence  of the  conversion  events  specified  in  the  preceding
paragraph  (i), the holders of the Series A Preferred  Stock shall,  upon notice
from the Corporation, surrender the certificates representing such shares at the
office  of the  Corporation  or of its  transfer  agent  for the  Common  Stock.
Thereupon,  there shall be issued and delivered to such holder a certificate  or
certificates  for the  number of shares of Class A Common  Stock  into which the
shares of Series A Preferred Stock so surrendered  were  convertible on the date
on which such conversion  occurred.  The  Corporation  shall not be obligated to
issue such certificates  unless  certificates  evidencing the shares of Series A
Preferred Stock being  converted are either  delivered to the Corporation or any
such  transfer  agent,  or  the  holder  notifies  the  Corporation   that  such
certificates  have been lost,  stolen or  destroyed  and  executes an  agreement
satisfactory  to the  Corporation  to indemnify  the  Corporation  from any loss
incurred by it in connection therewith.

                  (f)  Dividends.  In the event the  Corporation  shall  make or
issue,  or shall fix a record  date for the  determination  of holders of Common
Stock  entitled  to  receive a  dividend  or other  distribution  (other  than a
distribution in liquidation or other distribution otherwise provided for herein)
with respect to the Common Stock payable in (i)  securities  of the  Corporation
other  than  shares  of Common  Stock,  or (ii)  other  assets  (excluding  cash
dividends or distributions), then and in each such event provision shall be made
so that  the  holders  of the  Series  A  Preferred  Stock  shall  receive  upon
conversion  thereof  in  addition  to the  number  of  shares  of  Common  Stock
receivable  thereupon,  the number of  securities  or such  other  assets of the
Corporation  which they would have  received had their Series A Preferred  Stock
been  converted  into  Common  Stock  on the  date of such  event  and had  they
thereafter,  during the period from the date of such event to and  including the
Conversion  Date (as that term is hereafter  defined in Section 5(j)),  retained
such  securities  or such other  assets  receivable  by them during such period,
giving  application to all other adjustments called for during such period under
this  Section 5 with  respect  to the  rights  of the  holders  of the  Series A
Preferred Stock.

                  (g) Capital Reorganization or Reclassification.  If the Common
Stock  issuable  upon the  conversion  of the Series A Preferred  Stock shall be
changed into the same or  different  number of shares of any class or classes of
capital   stock,   whether   by   capital   reorganization,    recapitalization,
reclassification or otherwise (other than a subdivision or combination of shares
or stock  dividend  provided for elsewhere in this Section 5, or the sale of all
or substantially all of the  Corporation's  capital stock or assets to any other
person), than and in each such event the holder of each share of

                                       7
<PAGE>
                                    Page - 15


Series A Preferred  Stock shall have the right  thereafter to convert such share
into the kind and amount of shares of capital  stock and other  securities  and
property receivable upon such reorganization, recapitalization, reclassification
or other change by the holders of the number of shares of Common Stock into
which such shares of Series A Preferred Stock might have been converted
immediately prior to such reorganization, recapitalization, reclassification or
change, all subject to further adjustment as provided herein.

                  (h) Capital  Reorganization,  Merger or Sale of Assets.  If at
any time or from time to time  there  shall be a capital  reorganization  of the
Common  Stock  (other  than  a   subdivision,   combination,   recapitalization,
reclassification or exchange of shares provided for elsewhere in this Section 5)
or a merger or consolidation of the Corporation with or into another corporation
(other than a merger or  reorganization  involving only a change in the state of
incorporation  of the  Corporation  or the  acquisition  by the  Corporation  of
another business where the Corporation  survives as a going concern,  as further
provided in Section 3 hereof),  or the sale of all or  substantially  all of the
Corporation's  capital stock or assets to any other  person,  then, as a part of
such  reorganization,  merger, or consolidation or sale, provision shall be made
so that the holders of the Series A Preferred Stock shall thereafter be entitled
to receive upon  conversion of the Series A Preferred Stock the number of shares
of stock or other securities or property (including cash) of the Corporation, or
of the successor corporation resulting from such merger,  consolidation or sale,
to which such holder would have been  entitled if such holder had  converted its
shares  of  Series  A  Preferred  Stock   immediately   prior  to  such  capital
reorganization,  merger,  consolidation  or sale. In any such case,  appropriate
adjustment  shall be made in the application of the provisions of this Section 5
to the end that the  provisions  of this Section 5 (including  adjustment of the
Series A Applicable  Conversion Value then in effect and the number of shares of
Common Stock or other  securities  issuable  upon  conversion  of such shares of
Series A  Preferred  Stock)  shall be  applicable  after that event in as nearly
equivalent a manner as may be practicable.

                  The holders of at least a majority of the  outstanding  shares
of Preferred Stock, upon the occurrence of a capital  reorganization,  merger or
consolidation  of the Corporation,  or the sale of all or substantially  all its
capital  stock or assets,  as such  events are more fully set forth in the first
paragraph of this Section 5(h), shall have the option of electing  treatment for
the  Preferred  Stock as would be required for an event covered under either (i)
this Section 5(h) or (ii) Section 3 hereof regard a liquidation,  dissolution or
winding up of the affairs of the Corporation,  notice of which election shall be
submitted in writing to the  Corporation  at its principal  office no later than
twenty (20) business days before the effective date of such event.

                  (i) Certificate as to Adjustments;  Notice by Corporation.  In
each case of an adjustment or readjustment of the Series A Applicable Conversion
Rate,  the  Corporation  at its  expense  will  furnish  each holder of Series A
Preferred  Stock so affected  with a  certificate  prepared by the  Treasurer or
Chief Financial Officer of the

                                       8
<PAGE>
                                    Page - 16


Corporation, showing such adjustment or readjustment, and stating in detail the
facts  upon which such  adjustment  or readjustment is based.

                  (j)  Exercise  of  Conversion   Privilege.   To  exercise  its
conversion  privilege,  a holder of Series A Preferred Stock shall surrender the
certificate  or  certificates  representing  the shares  being  converted to the
Corporation  at its  principal  office,  and shall  give  written  notice to the
Corporation at that office that such holder elects to convert such shares.  Such
notice shall also state the name or names (with  address or  addresses) in which
the certificate or certificates for shares of Class A Common Stock issuable upon
such conversion  shall be issued.  The certificate or certificates for shares of
Series A Preferred  Stock  surrendered  for  conversion  shall be accompanied by
proper  assignment  thereof to the  Corporation or in blank.  The date when such
written notice is received by the Corporation,  together with the certificate or
certificates   representing  the  shares  of  Series  A  Preferred  Stock  being
converted,  shall be the "Conversion Date". As promptly as practicable after the
Conversion Date, the Corporation  shall issue and shall deliver to the holder of
the shares of Series A Preferred Stock being converted, or on its written order,
such  certificate  or  certificates  as it may  request  for the number of whole
shares of Class A Common Stock  issuable  upon the  conversion of such shares of
Series A Preferred  Stock in accordance  with the  provisions of this Section 5,
and cash,  as provided in Section 5(k), in respect of any fraction of a share of
Class A Common Stock issuable upon such  conversion.  Such  conversion  shall be
deemed to have been effected  immediately  prior to the close of business on the
Conversion  Date,  and at such time the  rights  of the  holder as holder of the
converted  shares of Series A Preferred  Stock shall cease and the  person(s) in
whose  name(s) any  certificate(s)  for shares of Class A Common  Stock shall be
issuable  upon such  conversion  shall be deemed to have  become  the  holder or
holders of record of the shares of Class A Common Stock represented thereby.

                  (k) Cash in Lieu of Fractional Shares. No fractional shares of
Class A Common  Stock or scrip  representing  fractional  shares shall be issued
upon the  conversion  of shares  of Series A  Preferred  Stock.  Instead  of any
fractional shares of Class A Common Stock which would otherwise be issuable upon
conversion of Series A Preferred Stock, the Corporation  shall pay to the holder
of the shares of Series A Preferred Stock which were converted a cash adjustment
in respect of such fractional  shares in an amount equal to the same fraction of
the  market  price  per share of the Class A Common  Stock (as  determined  in a
reasonable manner prescribed by the Board of Directors) at the close of business
on the Conversion  Date. The  determination  as to whether or not any fractional
shares are issuable shall be based upon the aggregate number of shares of Series
A Preferred  Stock being  converted at any one time by any holder  thereof,  not
upon each share of Series A Preferred Stock being converted.

                                       9
<PAGE>
                                    Page - 17


                  (l) Partial  Conversion.  In the event some but not all of the
shares of Series A Preferred Stock  represented by a certificate(s)  surrendered
by a holder are converted,  the  Corporation  shall execute and deliver to or on
the order of the holder,  at the expense of the  Corporation,  a new certificate
representing  the number of shares of Series A  Preferred  Stock  which were not
converted.

                  (m) Reservation of Common Stock. The Corporation  shall at all
times reserve and keep available out of its  authorized  but unissued  shares of
Class A Common Stock,  solely for the purpose of effecting the conversion of the
shares of the Series A  Preferred  Stock,  such  number of its shares of Class A
Common Stock as shall from time to time be sufficient  to effect the  conversion
of all outstanding  shares of the Series A Preferred Stock (including any shares
of Series A Preferred Stock represented by any warrants,  options,  subscription
or purchase rights for Series A Preferred Stock),  and if at any time the number
of  authorized  but  unissued  shares  of  Class A  Common  Stock  shall  not be
sufficient to effect the conversion of all then outstanding shares of the Series
A Preferred Stock (including any shares of Series A Preferred Stock  represented
by any warrants,  options,  subscriptions  or purchase  rights for such Series A
Preferred Stock),  the Corporation shall take such action as may be necessary to
increase  its  authorized  but  unissued  shares of Class A Common Stock to such
number of shares as shall be sufficient for such purpose.

                  (n)  Reissuance  of  Preferred  Stock.  No share or  shares of
Series A Preferred  Stock  acquired by the  Corporation by reason of redemption,
purchase, conversion or otherwise shall be reissued as Series A Preferred Stock,
but all such  shares  shall be  considered  authorized  but  unissued  shares of
Preferred Stock.

         6.       Restrictions and Limitations.

                  (a) Corporate Action;  Amendments to Charter.  The Corporation
shall not take any  corporate  action or  otherwise  amend  its  Certificate  of
Incorporation  without the approval by vote or written consent of the holders of
at least a majority of the then outstanding  shares of Preferred  Stock,  voting
together as a single class,  each share of Preferred Stock to be entitled to one
vote in each instance,  if such corporate  action or amendment would  materially
adversely  affect any of the rights,  preferences,  privileges of or limitations
provided  for  herein  for the  benefit  of any  shares  of  Preferred  Stock or
otherwise materially adversely affect the rights of the holders of the Preferred
Stock.   Without  limiting  the  generality  of  the  preceding  sentence,   the
Corporation  will not amend its Certificate of  Incorporation  or take any other
corporate  action  without the approval by the holders of at least a majority of
the then  outstanding  shares of Preferred  Stock,  voting  together as a single
class, if such amendment or corporate action would:

                                       10
<PAGE>
                                    Page - 18


                           (i) authorize or issue,  or obligate the  Corporation
                           to authorize or issue, additional shares of Preferred
                           Stock  senior  to or on a parity  with the  Preferred
                           Stock  with  respect  to   liquidation   preferences,
                           dividend rights or redemption rights,  except for the
                           designation and issuance of shares of Preferred Stock
                           approved in any instance by the holders of a majority
                           of the outstanding shares of Preferred Stock; or

                           (ii)  reduce  the amount  payable  to the  holders of
                           Preferred  Stock upon the  voluntary  or  involuntary
                           liquidation,   dissolution   or  winding  up  of  the
                           Corporation; or

                           (iii) adversely  affect the liquidation  preferences,
                           dividend rights,  voting rights or redemption  rights
                           of the holders of Preferred Stock; or

                           (iv) cancel or adversely modify the conversion rights
                           of the holders of  Preferred  Stock  provided  for in
                           Section 5 herein.

         7. No Dilution or Impairment. The Corporation will not, by amendment of
its  Certificate of  Incorporation  or through any  reorganization,  transfer of
capital stock or assets,  consolidation,  merger, dissolution,  issue or sale of
securities or any other voluntary action,  avoid or seek to avoid the observance
or performance of any of the terms of the Preferred Stock set forth herein,  but
will at all times in good faith assist in the carrying out of all such terms and
in the taking of all such action as may be necessary or  appropriate in order to
protect the rights of the holders of the  Preferred  Stock  against  dilution or
other  impairment.  Without  limiting  the  generality  of  the  foregoing,  the
Corporation  (a)  will  not  increase  the par  value  of any  shares  of  stock
receivable on the  conversion of the  Preferred  Stock above the amount  payable
therefor  on such  conversion,  and (b)  will  take all  such  action  as may be
necessary or appropriate in order that the  Corporation  may validly and legally
issue  fully paid and  nonassessable  shares of stock on the  conversion  of all
Preferred Stock from time to time outstanding.

         8.       Notices of Record Date.   In the event of:

                  (a) any taking by the  Corporation  of a record of the holders
of any class of securities  for the purpose of determining  the holders  thereof
who are entitled to receive any dividend or other distribution,  or any right to
subscribe for,  purchase or otherwise acquire any shares of capital stock of any
class or any other securities or property, or to receive any other right, or

                                       11
<PAGE>
                                    Page - 19


                  (b)  any  capital  reorganization  of  the  Corporation,   any
reclassification  or  recapitalization  of the capital stock of the Corporation,
any  merger or  consolidation  of the  Corporation,  or any  transfer  of all or
substantially all of the assets of the Corporation to any other corporation,  or
any other entity or person, or

                  (c) any voluntary or involuntary dissolution, liquidation or
winding up of the Corporation,

then and in each such event the Corporation  shall mail or cause to be mailed to
each  holder of Series A  Preferred  Stock a notice  specifying  (i) the date on
which  any  such  record  is to be  taken  for the  purpose  of  such  dividend,
distribution or right and a description of such dividend, distribution or right,
(ii)   the   date  on   which   any   such   reorganization,   reclassification,
recapitalization,  transfer, consolidation,  merger, dissolution, liquidation or
winding up is expected to become effective,  and (iii) the time, if any, that is
to be  fixed,  as to when the  holders  of  record  of  Common  Stock  (or other
securities) shall be entitled to exchange their shares of Common Stock (or other
securities)   for   securities   or  other   property   deliverable   upon  such
reorganization,  reclassification,  recapitalization,  transfer,  consolidation,
merger,  dissolution,  liquidation or winding up. Such notice shall be mailed by
first  class  mail,  postage  prepaid,  at least ten (10) days prior to the date
specified in such notice on which such action is to be taken.


EXECUTED this 14th day of August, 1996.

                                     /S/ Paul C. Desjourdy
                                     --------------------------------------
                                     Paul C. Desjourdy, Executive Vice President
ATTEST:


/S/ Jack H. Kessler
- -----------------------------------
Jack H. Kessler, Secretary

                                       12

<PAGE>
                                    Page - 1


                                                                   Exhibit 10.16

                              SYMBOLLON CORPORATION

                            STOCK PURCHASE AGREEMENT

         This Agreement dated as of August 14, 1996 is entered into by Symbollon
Corporation, a Delaware corporation,  residing at 122 Boston Post Road, Sudbury,
Massachusetts  01776  (the  "Company"),   Anthony  J.  Cantone  ("Cantone"),  an
individual  residing at Cantone  Research,  Inc., 675 Line Road,  Aberdeen,  New
Jersey 07747 ("Cantone") and Jack H. Kessler ("Kessler"), an individual residing
at 56  Presidential  Estate,  Southborough,  Massachusetts  01772  (Cantone  and
Kessler, and any subsequent valid transferee,  shall hereinafter be collectively
referred to as the "Purchasers").

         In consideration of the mutual promises and covenants  contained in the
Agreement, the parties hereto agree as follows:

         1.       Authorization and Sale of Shares.

                  1.1 Authorization. The Company has, or before the Closings (as
defined in Section 2) will have,  duly  authorized  and taken all such corporate
and other actions as is necessary for the issuance, sale and delivery,  pursuant
to the terms of this  Agreement,  of 444,444  shares of its  Series A  Preferred
Stock,  $.001 par value per share (the "Preferred  Shares").  The Certificate of
Designation,  Preferences  and Rights of Series A  Preferred  Stock is  attached
hereto as Exhibit 1.1.

                  1.2 Sale of  Shares.  Subject to the terms and  conditions  of
this  Agreement,  at the First  Closing the  Company  will sell and issue to the
Purchasers,  and the Purchasers will purchase, an aggregate of 444,444 Preferred
Shares for the  purchase  price of $1.125 per share in  accordance  with Exhibit
1.2.  Subject  to the terms and  conditions  of this  Agreement,  at the  Second
Closing  (as  defined in  Section  2),  the  Company  will sell and issue to the
Purchasers,  and the Purchasers  will purchase,  an aggregate of at least 50% of
222,222 shares of the Company's Class A Common Stock,  $.001 par value per share
(the "Common  Shares";  hereinafter  the Preferred  Shares and the Common Shares
purchased  pursuant  to this  Agreement  shall be  collectively  referred to the
"Shares") at the per share purchase price  determined in accordance with Section
2.

         2. The  Closings.  The closing of the sale and  purchase of the 444,444
Preferred  Shares to be issued at the First Closing  pursuant to this  Agreement
shall take place at the offices of the Company, or such other mutually agreeable
location  as the  parties may deem  appropriate,  on the date hereof  unless the
parties shall otherwise agree in writing (the "First  Closing").  Within fifteen
(15) days of receipt of a written  notice from  Purchasers  to the Company,  the
closing of the sale to and purchase by the Purchasers of at least 50% of 222,222
Common  Shares to be issued at the Second  Closing  pursuant  to this  Agreement
shall  take  place  at the  offices  of the  Company  no later  than  the  first
anniversary  of this  Agreement (or sooner,  if all of the conditions to closing
have theretofore  been satisfied),  or at such other time, date and place as are
mutually agreeable to the parties (the "Second Closing").


<PAGE>
                                    Page - 2


         The First Closing and the Second Closing are sometimes each referred to
hereinafter as a "Closing" and  collectively as the "Closings".  The date of the
First  Closing is  hereinafter  referred to as the "First  Closing Date" and the
date of the Second  Closing is  hereinafter  referred to as the "Second  Closing
Date".

         At each of the Closings,  the Company  shall deliver to the  Purchasers
certificates  for the  number  of  Shares  being  purchased  by the  Purchasers,
registered in the name of the Purchasers,  against payment to the Company of the
purchase price therefor, by wire transfer.  The purchase price per share for the
Common Shares to be purchased at the Second Closing shall be $2.00 if the Second
Closing Date is on or before March 31, 1997 or $3.00 if the Second  Closing Date
is after March 31, 1997.

         3.      Representations of the Company.  The Company hereby represents
and warrants to the Purchasers as follows:

                  3.1  Organization  and Standing.  The Company is a corporation
duly  organized,  validly  existing and in good  standing  under the laws of the
State of Delaware  and has full  corporate  power and  authority  to conduct its
business as  presently  conducted  and as proposed to be  conducted by it and to
enter  into  and  perform  this  Agreement  and to  carry  out the  transactions
contemplated  hereby.  The  Company is  qualified  to do  business  as a foreign
corporation and is in good standing in each  jurisdiction in which the nature of
the business  transacted  by it or the  character or location of its  properties
requires  such  qualification,  except where the failure to so qualify would not
have a Material Adverse Effect.

                  3.2  Capitalization.  The  authorized  capital  stock  of  the
Company as of the date hereof  consists of  18,750,000  shares of Class A Common
Stock,  $.001 par value per  share,  1,250,000  shares of Class B Common  Stock,
$.001 par value per share, and 5,000,000  shares of Preferred  Stock,  $.001 par
value per share,  of which 1,283,699  shares of Class A Common Stock,  1,199,713
shares of Class B Common  Stock and no shares of Preferred  Stock are  presently
outstanding  without taking into effect the  transactions  contemplated  by this
Agreement. There are 1,572,080 Class A Warrants (each of which is exercisable to
purchase  one  share  of Class A  Common  Stock  and one  Class B  Warrant)  and
1,227,920  Class B Warrants  (each of which is exercisable to purchase one share
of Class A Common  Stock)  presently  outstanding.  There are options  presently
outstanding  to purchase  100,000 Units (a Unit consists of one share of Class A
Common Stock,  one Class A Warrant and one Class B Warrant),  and 286,333 shares
of Class A Common Stock. All shares  outstanding on the date hereof are, and any
shares that will be issued under the Certificate of Incorporation,  when issued,
will be, duly authorized, validly issued and fully paid and nonassessable. There
are no preemptive  rights,  rights of first  refusal,  or other  similar  rights
available to the existing  holders of Common  Stock or other  securities  of the
Company.

                                       2
<PAGE>
                                    Page - 3


                  3.3 Issuance of Shares. The issuance, sale and delivery of the
Shares have been, or will be on or prior to the  applicable  Closing Date,  duly
authorized by all  necessary  corporate  action on the part of the Company.  The
Shares,  when issued,  sold and delivered against payment therefor in accordance
with the provisions of this Agreement,  will be duly and validly  issued,  fully
paid and non-assessable and free and clear of any liens or preemptive, rights of
first refusal, or other similar rights.

                  3.4 Authority for  Agreement;  No  Conflicts.  The  execution,
delivery and performance by the Company of this Agreement,  and the consummation
of the  transactions  contemplated  hereby,  have  been duly  authorized  by all
necessary  corporate action. This Agreement has been duly executed and delivered
by the Company, enforceable against it in accordance with its terms, except that
such  enforcement  may be subject to  applicable  moratorium  and  similar  laws
affecting  creditors'  rights,  and  the  remedy  of  specific  performance  and
injunctive relief may be subject to equitable  defenses and to the discretion of
the court for which  proceeding  therefor  may be  brought.  The  execution  and
delivery of this Agreement and performance of the  transactions  contemplated by
this  Agreement  and  compliance  with its  provisions  by the Company  will not
conflict  with or  result  in any  breach  of any of the  terms,  conditions  or
provisions  of, or  constitute a default  under,  or require a consent or waiver
under,  its Certificate of Incorporation or By-Laws (each as amended to date) or
any  indenture,  lease,  agreement or other  instrument  to which the Company is
party or by which it or any of its  properties is bound,  or violate any decree,
judgment,  order, statute, rule, regulation or other provision of law applicable
to the  Company,  except in each case as would not result in a Material  Adverse
Effect.

                  3.5 Governmental  Consents.  No consents,  approval,  order or
authorization  of, or  regulation,  qualification,  designation,  declaration or
filing with, any  governmental  authority is required on the part of the Company
in connection  with the  execution and delivery of this  Agreement or the offer,
issuance,  sale and  delivery  of the  Shares  or the other  transactions  to be
consummated  at any  Closing,  as  contemplated  by this  Agreement,  except for
compliance with the provisions of any laws as to which the failure to be made or
obtained would not result in a Material Adverse Effect and such filings as shall
have  been  made  prior to and shall be  effective  on and as of the  applicable
Closing.  Based on the  representations  made by the  Purchasers in Section 4 of
this  Agreement,  the offer and sale of the Shares to the Purchasers  will be in
compliance with applicable federal and state securities laws.

                  3.6 Corporate  Condition.  The Company's condition was, in all
material  respects,  as described in the Disclosure  Documents at the respective
dates thereof,  including  without  limitation the reports filed pursuant to the
Exchange  Act.  There  has been no  material  adverse  change  in the  Company's
business,  financial  condition or prospects since June 30, 1996. The Disclosure
Documents  are true and correct as of their  respective  dates,  in all material
respects,  and the financial  statements  contained in the Disclosure  Documents
have been prepared in accordance with generally accepted accounting  principles,
consistently  applied,  and fairly present the financial position and results of
operation and cash flows of the Company, for the periods then

                                       3
<PAGE>
                                    Page - 4


ended.  Without  limiting  the  foregoing,  there are no pending  or  threatened
litigation or other  material  liabilities,  contingent or actual,  that are not
disclosed in the Disclosure  Documents except as incurred in the ordinary course
of business  since June 30, 1996.  The Company has paid all material taxes which
are due,  except for taxes which it reasonably  disputes,  or to the best of the
Company's knowledge,  threatened against the Company, except as disclosed in the
Disclosure Documents. This Agreement and the Disclosure Documents do not contain
any untrue  statement  of a material  fact and do not omit to state any material
fact  required  to be stated  therein  or herein  necessary  to make  statements
contained  therein or herein not  misleading  in the light of the  circumstances
under which they were made.

                  3.7 Current Public Information.  The Company has filed all the
materials  required  to be filed as reports  pursuant to the  Exchange  Act on a
timely basis. Except for the Disclosure Documents, since June 30, 1996 there has
been no filings made by the Company under the Exchange Act or the Securities Act
other than filings required by Section 16 of the Exchange Act. The Company filed
the Quarter  Report on Form 10-QSB for the quarter ended June 30, 1996 on August
14, 1996.

                  3.8  Brokers,  Etc.  The  Company  has dealt  with no  broker,
finder,  commission  agent or person in connection with the offer or sale of the
Shares  and the  transactions  contemplated  by this  Agreement  and is under no
obligation to pay any broker's fees, finder's fees, or other fees or commissions
in connection with such transactions.

         4.       Representations of the Purchasers.  Each of the Purchasers,
severally and not jointly, represents and warrants to the Company as follows:

                  4.1  Investment.  The  Purchasers are acquiring the Shares for
their  own  accounts  for  investment  and not  with a view  to,  or for sale in
connection with, any  distribution  thereof,  nor with any present  intention of
distributing  or selling the same.  The Purchasers  are  "Accredited  Investors"
within the meaning of Rule 501(a)(4) or (5) of Regulation D under the Securities
Act. The Purchasers  understand that the Shares have not been  registered  under
the  Securities  Act by reason of a  specific  exemption  from the  registration
provisions  thereof which depends upon, among other things, the bona fide nature
of their investment intent as expressed herein.

                  4.2 Power and Authority.  The  Purchasers  have the full power
and authority to execute,  deliver and perform this  Agreement.  This Agreement,
when  executed and  delivered  by the  Purchasers,  will  constitute a valid and
legally binding obligation of the Purchasers, enforceable in accordance with its
terms.

                  4.3 State of  Jurisdiction.  Cantone  represents  and warrants
that all matters and actions  relevant  to his  considerations,  evaluations  or
executions  of this  Agreement or the  transactions  contemplated  hereby by him
including, without limitation, the receipt of any offer to purchase, the receipt
and  review  of  any  documents  or  other  materials   relevant   hereto,   the
participation in any communications with the Company or

                                       4
<PAGE>
                                    Page - 5


any other party, and the
consummation  of the  transactions  contemplated  hereby  occurred solely in New
Jersey or  Massachusetts.  Kessler  represents and warrants that all matters and
actions relevant to his consideration, evaluation or execution of this Agreement
or the transactions  contemplated  hereby by him including,  without limitation,
the receipt of any offer to purchase, the receipt and review of any documents or
other materials relevant hereto,  the participation in any  communications  with
the  Company  or any  other  party,  and the  consummation  of the  transactions
contemplated hereby occurred solely in New Jersey or Massachusetts.

                  4.4  Independent  Investigation.  The  Purchasers  have relied
solely  upon an  independent  investigation  made by  each  of  them  and  their
representatives and have, prior to the date hereof, been given access to and the
opportunity to examine all material contracts and documents of the Company which
have been filed as exhibits to the Company's  filings made under the  Securities
Act and the Exchange Act through  publicly  available means. The Purchasers have
been  provided with copies of the Company's (i) Annual Report on Form 10-KSB for
the year ended December 31, 1995;  (ii) Quarterly  Report on Form 10-QSB for the
quarter  ended March 31,  1996;  (iii)  Quarterly  Report on Form 10-QSB for the
quarter ended June 30, 1996; (iv) Risk Factors,  attached hereto as Exhibit 4.4,
and (v) Proxy  Statement  dated April 15, 1996  (collectively,  the  "Disclosure
Documents").  The Purchasers have requested,  received,  reviewed and considered
all  information  they  deem  relevant  in making a  decision  to  execute  this
Agreement  and to purchase the Shares.  In making their  investment  decision to
purchase  the  Shares,  the  Purchasers  are not  relying on any oral or written
representations  or  assurances  from the  Company  or any  other  person or any
representation  of the  Company or any other  person  other than as set forth in
this Agreement,  or the Disclosure Documents.  The Purchasers are knowledgeable,
sophisticated  and experienced in making,  and are qualified to make,  decisions
with respect to investments in restricted securities.

                  4.5 Economic Risk. The Purchasers  understand and  acknowledge
that an investment in the Shares  involves a high degree of risk. The Purchasers
acknowledge  that there are  limitations  on the  liquidity  of the Shares.  The
Purchasers  represent  that the Purchasers are able to bear the economic risk of
an investment in the Shares,  including a possible total loss of investment.  In
making  this  statement,  the  Purchasers  hereby  represent  and warrant to the
Company that the Purchasers have adequate means of providing for the Purchasers'
current needs and contingencies;  that the Purchasers are able to afford to hold
the Shares for an indefinite period;  that the Purchasers further represent that
the  Purchasers  have such  knowledge  and  experience in financial and business
matters that the  Purchasers  are capable of evaluating  the merits and risks of
the  investment  in the Shares to be  received by the  Purchasers;  and that the
Purchasers  are   sophisticated   accredited   investors  with  experience  with
development  stage  issuers  engaged in biotech and  pharmaceutical  businesses.
Further, the Purchasers represent,  as of the Closing Dates, that the Purchasers
have no present need for liquidity in the Shares and the  Purchasers are willing
to accept such  investment  risks.  The Purchasers  have reviewed the Disclosure
Documents, including, without limitation, the Risk Factors.

                                       5
<PAGE>
                                    Page - 6


                  4.6 No  Conflicts.  The  execution of and  performance  of the
transactions  contemplated  by this Agreement and compliance with its provisions
by the  Purchasers  will not conflict with or result in any breach of any of the
terms,  conditions or provisions of, or constitute a default under, or require a
consent or waiver under any indenture,  lease,  agreement or other instrument to
which  either  of the  Purchasers  is a party or by  which  they or any of their
properties are bound, or violate any decree,  judgment,  order,  statute,  rule,
regulation  or  other  provision  of law  applicable  to the  Purchasers,  which
violation  would  prevent,  impair,  hinder  or delay  the  consummation  of the
transactions contemplated by this Agreement.

                  4.7 Governmental  Consents.  No consents,  approval,  order or
authorization  of, or  regulation,  qualification,  designation,  declaration or
filing  with,  any  governmental  authority  is  required  on  the  part  of the
Purchasers  in connection  with the execution and delivery of this  Agreement or
the purchase of the Shares or the other  transactions  to be  consummated at any
Closing, as contemplated by this Agreement.

                  4.8  Cooperation.  The  Purchasers  covenant  that they  shall
cooperate  with the Company in connection  with all  reasonable  requests by the
Company  to  provide  information   necessary  for  any  filings,   notices  and
applications  to be  made by the  Company  in  connection  with  any  regulatory
matters.

                  4.9 Brokers,  Etc. The  Purchasers  have dealt with no broker,
finder,  commission  agent or person in connection with the offer or sale of the
Shares and the  transactions  contemplated  by this  Agreement  and are under no
obligation to pay any broker's fees, finder's fees, or other fees or commissions
in connection with such transactions.

         5.  Conditions to the  Obligations  of the  Purchasers at the Closings.
Notwithstanding anything to the contrary contained herein, the obligation of the
Purchasers  to  purchase  Shares  at  each of the  Closings  is  subject  to the
fulfillment,  or the  waiver  by  the  Purchasers,  of  each  of  the  following
conditions on or before each Closing:

                  5.1  Accuracy  of   Representations   and   Warranties.   Each
representation  and warranty of the Company  contained in Section 3 hereof shall
be true on and as of each Closing Date in all  material  respects  with the same
effect as though such  representation  and  warranty  had been made on and as of
that date.

                  5.2 Performance. The Company shall have performed and complied
with all agreements and conditions  contained herein required to be performed or
complied with by the Company prior to or at each Closing.

         6.  Conditions  to  the  Obligations  of the  Company.  Notwithstanding
anything to the contrary  contained  herein,  the  obligations of the Company to
issue,  sell and deliver at each Closing the Shares are subject to  fulfillment,
on or before each Closing Date, of each of the following conditions:

                                       6
<PAGE>
                                    Page - 7


                  6.1  Accuracy  of   Representations   and   Warranties.   Each
representation  and  warranty of the  Purchasers  contained  in Section 4 hereof
shall be true on and as of each Closing Date in all material  respects  with the
same effect as though such  representation  and warranty had been made on and as
of that date.

                  6.2  Performance.  The  Purchasers  shall have  performed  and
complied with all  agreements  and conditions  contained  herein  required to be
performed or complied with by the Purchasers prior to or at each Closing.

                  6.3 Second Closing.  The Company's  obligation to issue,  sell
and deliver the Common Shares at the Second  Closing is contingent  upon (i) the
consummation of the First Closing, (ii) receipt by the Company of written notice
from the  Purchasers  of its intent to purchase  at least 50% of 222,222  Common
Shares at the Second  Closing,  (iii) the  conversion  by the  Purchasers of the
Preferred  Shares into Class A Common Stock,  and (iv) the  consummation  of the
Second Closing before the first anniversary of the date of this Agreement.

         7.       Transfer Restrictions and Registration.

                  7.1  Legend.  Unless  and  until  otherwise  permitted,   each
certificate representing the Shares shall be stamped or otherwise imprinted with
a legend in substantially the following form:

         "THE SHARES  EVIDENCED  BY THIS  CERTIFICATE  HAVE NOT BEEN  REGISTERED
UNDER THE SECURITIES ACT OF 1933, AS AMENDED,  OR ANY STATE  SECURITIES  LAW. NO
TRANSFER,  SALE OR  OTHER  DISPOSITION  OF  THESE  SHARES  MAY BE MADE  UNLESS A
REGISTRATION  STATEMENT WITH RESPECT TO THESE SHARES HAS BECOME  EFFECTIVE UNDER
SAID ACT,  OR  SYMBOLLON  CORPORATION  IS  FURNISHED  WITH AN OPINION OF COUNSEL
SATISFACTORY  IN  FORM  AND  SUBSTANCE  TO IT  THAT  SUCH  REGISTRATION  IS  NOT
REQUIRED."

                  7.2  Required  Registration.  The  Purchasers  shall  have the
right, exercisable upon written notice to the Company, to request the Company to
file a registration  statement on the Form S-3 (or other applicable form, as the
Company determines  appropriate)  covering the Shares purchased  hereunder on or
after the six-month  anniversary of the date of this Agreement.  Upon receipt of
any such notice,  the Company shall, as expeditiously  as possible,  effect such
registration,  obtain any  governmental  approval  and effect  listing  with any
securities exchange on which the stock of the Company is then listed,  which may
be required to permit the Purchasers to dispose of the Shares. The Company shall
use its best efforts to maintain the effectiveness of the registration statement
until the first to occur of (i) the completion of the distribution of the Shares
covered  thereby,  (ii)  such time as the  Shares  covered  thereby  may be sold
without   restrictive  legend  under  Rule  144  or  other  exemption  from  the
registration  requirements  of the  Securities  Act,  or (iii) 180 days from the
effective  date of the  registration  statement.  The Company agrees to keep the
registration statement current

                                       7
<PAGE>
                                    Page - 8


during such period.  The Company's  obligation
shall be  limited to one  registration;  provided,  that if the  Second  Closing
occurs,  the Company's  obligation  shall be limited to two  registrations.  The
Company shall not be obligated to effect a  registration  covering the Shares if
at the  time of  request,  all  such  Shares  can be  immediately  sold  without
restrictive  legend  under  Rule 144 or other  exemption  from the  registration
requirements of the Securities Act. The Company shall not be required to cause a
registration statement to become effective pursuant to this Section 7.2 prior to
120 days  following the effective  date of the most recent  registration  by the
Company under the Securities Act.

                  7.3 Piggy-Back Registration Rights. If the Company at any time
proposes to register  under the  Securities  Act any of its Common  Stock on any
form on which  the  Shares  may be  included,  except  shares  to be  issued  in
connection with any acquisition of any entity or business,  shares issuable upon
the exercise of stock options or shares  issuable  pursuant to employee  benefit
plans,  it will  each such time give  written  notice to the  Purchasers  of its
intention  to do so.  If the  Purchasers  desire  to have  any of  their  Shares
purchased  hereunder included in such registration,  they shall,  within 20 days
after their  receipt of such notice from the Company,  notify the Company of the
number of shares  which they desire to have so included  and the manner in which
they propose to dispose of such  Shares.  The Company will cause all such Shares
requested to be  registered  by the  Purchasers to be registered or qualified to
the  extent  requisite  to permit the sale or other  disposition  thereof in the
manner described by the Purchasers;  provided,  however,  that if, in connection
with  the  offering  of  Common  Stock  pursuant  to a  registration  under  the
Securities Act, such offering  includes shares of Common Stock being sold by the
Company and the managing  underwriter shall impose a limitation on the number of
shares of the  Common  Stock  which  may be  included  in any such  registration
statement  because,  in its judgment,  such limitation is necessary to effect an
orderly public distribution and such limitation is imposed pro rata with respect
to all securities which have an incidental or "piggy back" rights to be included
in the  registration  statement  and as to which  inclusion  has been  requested
pursuant to such a right, and no outstanding  securities are included other than
pursuant to such a right, then the Company shall be obligated to include in such
registration statement only such limited portion of the Shares which it has been
requested hereunder to include.

                  7.4 Non-public  Information.  Notwithstanding  anything to the
contrary in this  Section 7, the  Company  shall have the right (i) to defer the
initial filing or request for  acceleration of effectiveness of any registration
or (ii) after effectiveness,  to suspend  effectiveness of any such registration
statement,  if, in the good  faith  judgment  of the board of  directors  of the
Company,  such delay in filing or requesting  acceleration of  effectiveness  or
such  suspension  of  effectiveness  is necessary  in light of the  existence of
material non-public  information (financial or otherwise) concerning the Company
disclosure of which at the time is not, in the opinion of the board of directors
of the Company,  (A)  otherwise  required  and (B) in the best  interests of the
Company;  provided  however  that  the  Company  will use its  best  efforts  to
terminate such delay or suspension as soon as practicable.

                                       8
<PAGE>
                                    Page - 9


                  7.5 Payment of  Expenses.  The Company  shall bear the expense
(excluding underwriting  commissions,  dealers' fees, brokers' fees, concessions
applicable  to the Shares,  legal fees and  expenses of the  Purchasers  and any
out-of-pocket  expenses of the Purchasers) of all registrations pursuant to this
Section 7.

                  7.6  Indemnification.  The Company  hereby agrees to indemnify
and hold harmless the Purchasers and any underwriter against all losses, claims,
damages,  liabilities  and expenses  (under the Applicable  Securities  Laws, or
common law or  otherwise)  caused by any  untrue  statement  or  alleged  untrue
statement  of a  material  fact  contained  in  any  registration  statement  or
prospectus  (and as amended or  supplemented if the Company shall have furnished
any  amendments or  supplements  thereto) or any  preliminary  prospectus or any
other document  prepared  and/or  furnished to the  Purchasers  incident to such
registration  statements  or  prospectus,  or caused by any  omission or alleged
omission  to state  therein a material  fact  required  to be stated  therein or
necessary  to make the  statements  therein  complete or not  misleading  except
insofar as such losses, claims,  damages,  liabilities or expenses are caused by
any untrue statement or omission  contained in information  furnished in writing
to the Company by the Purchasers  expressly for use therein.  In connection with
any registration  statement in which the Purchasers are participating,  and as a
condition to the obligation of the Company to cause any Shares of the Purchasers
to be  included in a  registration  statement  pursuant  to this  Section 7, the
Purchasers  will  furnish to the Company in writing  such  information  as shall
reasonably  be  requested  by the  Company  for  use in  any  such  registration
statement or  prospectus  and will  indemnify,  severally  and not jointly,  the
Company,  its  directors  and  officers,  each person,  if any, who controls the
Company within the meaning of the Applicable  Securities Laws, such underwriters
and each  person  who  controls  such  underwriters  within  the  meaning of the
Applicable Securities Laws, against any losses, claims, damages, liabilities and
expenses  resulting from any untrue  statement or alleged untrue  statement of a
material fact or any omission or alleged omission of a material fact required to
be stated in the registration  statement or prospectus and necessary to make the
statements therein complete or not misleading,  but only to the extent that such
untrue statement or omission is contained in information so furnished in writing
by the Purchasers expressly for use therein.

         Promptly  after receipt by any person  entitled to indemnity  hereunder
(the "Indemnified Party") of notice of the commencement of any action in respect
of  which   indemnity  may  be  sought  against  another  party  hereunder  (the
"Indemnifying  Party") such Indemnified Party will notify the Indemnifying Party
in  writing  of  the  commencement  thereof,  and,  subject  to  the  provisions
hereinafter  stated,  the  Indemnifying  Party shall  assume the defense of such
action  (including  the employment of counsel,  who shall be counsel  reasonably
satisfactory to such Indemnified Party), and the payment of expenses as incurred
insofar as such action shall relate to any alleged liability in respect of which
indemnity may be sought against the Indemnifying  Party.  Such Indemnified Party
shall  have the right to  employ  separate  counsel  in any such  action  and to
participate  in the defense  thereof but the fees and  expenses of such  counsel
shall not be at the expense of the Indemnifying  Party unless (i) the employment
of such counsel has been  specifically  authorized by the Indemnifying  Party or
(ii) the

                                       9
<PAGE>
                                   Page - 10


Indemnifying  Party  shall have failed to assume the defense of such action or
proceeding.  The Indemnifying  Party shall not be liable to indemnify any person
for any settlement of any such action effected without the Indemnifying  Party's
consent, which consent shall not be unreasonably withheld.

         If the indemnification  provided for in this Section is held by a court
of  competent  jurisdiction  to be  unavailable  to the  Indemnified  Party with
respect to any loss,  liability,  claim,  damage or expense  referred to herein,
then the  Indemnifying  Party, in lieu of indemnifying  such  Indemnified  Party
hereunder,  shall  contribute to the amount paid or payable by such  Indemnified
Party as a result of such  loss,  liability,  claim,  damage or  expense in such
proportion as is appropriate  to reflect the relative fault of the  Indemnifying
Party  on the  one  hand  and of the  Indemnified  Party  on the  other  hand in
connection  with the  statements  or  omissions  which  resulted  in such  loss,
liability,  claim,  damage or  expense as well as any other  relevant  equitable
considerations. The relevant fault of the Indemnifying Party and the Indemnified
Party shall be  determined  by  reference  to, among other  things,  whether the
untrue or alleged untrue statement of a material fact or the omission to state a
material fact relates to information  supplied by the  Indemnifying  Party or by
the Indemnified  Party and the parties'  relative intent,  knowledge,  access to
information and opportunity to correct or prevent such statement or omission.

                  7.7 Exchange Act Registration Requirements.  The Company shall
use its best efforts to remain subject to the reporting  requirements  of either
Section 13 or Section 15(d) of the Exchange Act. The Company shall file with the
Commission in a timely manner such  information  as the  Commission  may require
under either of said Sections,  and shall take all  reasonable  action as may be
required  to be taken  under  the  Exchange  Act to permit  sales of the  Shares
pursuant to Rule 144 (or any similar or successor  exemptive  rule  hereafter in
effect)  and the use of Form S-3 (or any  similar  form which  hereafter  may be
promulgated under the Securities Act) for registration of the Shares.

                  7.8 Notice. The Company shall provide notice to the Purchasers
of any "stop order" or other notice  affecting the Purchasers  right to sell the
Shares under any effective registration statement.

                  7.9 Only Common Stock to be Registered.  The Company shall not
be required  pursuant to any  provision of this Section 7 to register or qualify
any  securities  other  than the Class A Common  Stock of the  Company,  and the
Company may require as a condition  of any such  registration  or  qualification
that any Shares to be included in such registration or qualification  other than
the Class A Common  Stock be converted to Class A Common Stock no later than the
effective date of any registration or qualification effected pursuant to Section
7.

                                       10
<PAGE>
                                   Page - 11


         8.       Definitions.  When used in this Agreement, the following terms
shall have the meanings indicated.

                  "Applicable Securities Laws" means the applicable Federal
 and state securities laws.

                  "Cantone" means Anthony J. Cantone.

                  "Class A Common  Stock"  means  the  Company's  Class A Common
Stock, $.001 par value per share.

                  "Class B Common  Stock"  means  the  Company's  Class B Common
Stock, $.001 par value per share.

                  "Closing" shall have the meaning specified in Section 2.

                  "Commission" means the Securities and Exchange Commission.

                  "Common Shares" shall have the meaning specified in Section
 1.2.

                  "Common Stock" means,  collectively,  the Class A Common Stock
and the Class B Common Stock.

                  "Company" means Symbollon Corporation, a Delaware corporation.

                  "Disclosure Documents" shall have the meaning specified in
 Section 4.4.

                  "Exchange Act" means the Securities Exchange Act of 1934,
as amended.

                  "First Closing" shall have the meaning specified in Section 2.

                  "First Closing Date" shall have the meaning specified in
Section 2.

                  "Indemnified Party" shall have the meaning specified in
Section 7.6.

                  "Indemnifying Party" shall have the meaning specified in
Section 7.6.

                  "Kessler" means Jack H. Kessler.

                  "Material  Adverse Effect" means a material  adverse effect on
the business,  prospects,  condition (financial or otherwise), assets or results
of operations of the Company taken as a whole.

                  "Purchasers" means Anthony J. Cantone and Jack H. Kessler, and
any subsequent valid transferee.

                                       11
<PAGE>
                                   Page - 12


                  "Preferred Shares" shall have the meaning specified in
Section 1.1.

                  "Second Closing" shall have the meaning specified in
Section 2.

                  "Second Closing Date" shall have the meaning specified in
Section 2.

                  "Securities Act" means the Securities Act of 1933, as amended.

                  "Shares" shall have the meaning specified in Section 2.

                  "Units" means  securities of the Company each of which consist
of one  share of Class A Common  Stock,  one  Class A  Warrant  and one  Class B
Warrant.

         9. Notices. All notices,  requests,  consents, and other communications
under this  Agreement  shall be in writing and shall be delivered in person with
receipt  acknowledged  or mailed by first class  certified or  registered  mail,
return  receipt  requested,  postage  prepaid,  by reputable  overnight  mail or
courier,  with  receipt  confirmed,  or by telecopy  and  confirmed  by telecopy
answerback, addressed as follows:

         If to the Company:         Symbollon Corporation
                                    122 Boston Post Road
                                    Sudbury, Massachusetts 01776
                                    Telephone: (508) 443-0165
                                    Telecopy: (508) 443-0166
                                    Attn: President

                                       and

         If to Cantone:             Anthony J. Cantone
                                    Cantone Research, Inc.
                                    675 Line Road
                                    Aberdeen, New Jersey 07747
                                    Telephone: (908) 441-0007
                                    Telecopy: (908) 441-0002

                                       and

         If to Kessler:             Jack H. Kessler
                                    56 Presidential Estate
                                    Southborough, Massachusetts 01772
                                    Telephone: (508) 229-3134
                                    Telecopy: (508) 229-3136

                                       12
<PAGE>
                                   Page - 13


or at such other  address or addresses as may have been  furnished in writing by
any party to the other in  accordance  with the  provisions  of this  Section 9.
Notices and other  communications  provided in  accordance  with this  Section 9
shall be deemed delivered upon receipt.

         10. Entire  Agreement.  This Agreement,  together with the Exhibits and
documents  incorporated by reference  herein,  embodies the entire agreement and
understanding  between the parties  hereto  with  respect to the subject  matter
hereof and supersedes all prior agreements and  understandings  relating to such
subject matter.

         11. Amendments and Waivers.  Except as otherwise expressly set forth in
this Agreement,  any term of this Agreement may be amended and the observance of
any term of this  Agreement may be waived  (either  generally or in a particular
instance  and either  retroactively  or  prospectively),  only with the  written
consent of the Company and the  Purchasers.  Any amendment or waiver effected in
accordance  with this Section 11 shall be binding upon each party. No waivers of
or exceptions to any terms, condition or provision of this Agreement, in any one
or more  instances,  shall be  deemed  to be,  or  construed  as, a  further  or
continuing waiver of any such term, condition or provision.

         12.      Counterparts.  This Agreement may be executed in one or more
counterparts, each of which shall be deemed to be an original, but all of which
shall be one and the same document.

         13.      Section Headings.  The section headings are for the
convenience of the parties and in no way alter, modify, amend, limit, or
restrict the contractual obligations of the parties.

         14.      Severability.  The invalidity or unenforceability of any
provision of this Agreement shall not affect the validity or enforceability
of any other provision of this Agreement.

         15.      Governing Law.  This Agreement shall be governed by and
construed in accordance with the law of The Commonwealth of Massachusetts.

         16.  Successors and Assigns.  This Agreement  shall be binding upon the
parties  hereto and their  respective  successors and assigns and shall inure to
the benefit of the parties  hereto.  The  Purchasers may not assign their rights
hereunder  without the prior written  consent of the Company except to an entity
controlled  by either of the  Purchasers,  or to an immediate  family  member of
either of the Purchasers.

                                       13
<PAGE>
                                   Page - 14


         IN WITNESS  WHEREOF,  the parties  have  executed  and  delivered  this
Agreement as of the date first above written.


SYMBOLLON CORPORATION               PURCHASERS



By: /S/ Paul C. Desjourdy            /S/ Anthony J. Cantone
   ---------------------            ----------------------
   Paul C. Desjourdy,               Anthony J. Cantone
   Vice President

                                    /S/ Jack H. Kessler
                                    ----------------------
                                    Jack H. Kessler


                                       14
<PAGE>
                                   Page - 15


                                   Exhibit 1.1

                    CERTIFICATE OF DESIGNATIONS, PREFERENCES

                     AND RIGHTS OF SERIES A PREFERRED STOCK

                                       OF

                              SYMBOLLON CORPORATION

The undersigned officers of Symbollon  Corporation,  a corporation organized and
existing under the General  Corporation Law of the State of Delaware,  do hereby
certify  that,   pursuant  to  authority   conferred  by  the   Certificate   of
Incorporation,  and  pursuant  to the  provisions  of Section 151 of the General
Corporation  Law of the State of  Delaware,  the Board of Directors of Symbollon
Corporation  at a meeting duly  authorized  and validly held on August 13, 1996,
adopted  a  resolution  providing  for  certain  powers,  designations,  number,
preferences  and  relative,  participating,  optional or other  rights,  and the
qualifications, limitations or restrictions thereof, of 444,444 shares of Series
A Preferred Stock, $.001 par value, which resolution is as follows:

         RESOLVED:  That  pursuant  to  Article  Fourth  of the  Certificate  of
         Incorporation  of this  Corporation,  the  Board  of  Directors  hereby
         establishes  a series  of  Preferred  Stock,  $.001 par  value,  of the
         Corporation   having  the  following  powers,   designations,   number,
         preferences  and relative,  participating,  option of or others special
         rights, and qualifications, limitations or restrictions thereof:

            Description and Designation of Series A Preferred Stock

         1.  Designation.  A  total  of  444,444  shares  of  the  Corporation's
Preferred  Stock shall be  designated  the "Series A Preferred  Stock".  As used
herein,  the  term  "Preferred  Stock"  used  without  reference  to  any  other
outstanding  series of Preferred  Stock of the  Corporation as from time to time
may be  outstanding  means  all such  outstanding  series  of the  Corporation's
Preferred  Stock,  share for share alike and without  distinction  as to series,
except as otherwise  expressly  provided for herein, or as the context otherwise
requires.

         2.  Dividends.

             (a)  Computation  of  Cumulative  Dividends.  The  holders  of  the
outstanding shares of Series A Preferred Stock shall be entitled to receive, out
of funds legally available therefor,  cumulative dividends at the annual rate of
$0.09 per share.  Cumulative  dividends on the Series A Preferred Stock shall be
payable if, as and when declared.

                                       1
<PAGE>
                                   Page - 16


             Dividends on the Series A Preferred  Stock shall accrue from day to
day on each share of Series A Preferred Stock from the date of original issuance
of such share, whether or not earned or declared, and shall accrue until paid.

             All numbers  relating to calculation of cumulative  dividends shall
be subject to equitable  adjustment  in the event of any stock  dividend,  stock
split, combination, reorganization, recapitalization,  reclassification or other
similar  event  involving  a change in the  capital  structure  of the  Series A
Preferred  Stock.  Such  dividends  on the  Series A  Preferred  Stock  shall be
cumulative  so that if such  dividends  in  respect of any  previous  or current
annual dividend period, at the annual rate specified above,  shall not have been
paid or declared and a sum  sufficient  for the payment  thereof set apart,  the
deficiency  shall first be fully paid before any dividend or other  distribution
shall be paid or declared and set apart for the Class A Common Stock and Class B
Common Stock  (collectively,  the "Common  Stock").  Upon any  conversion of the
Series A Preferred  Stock under  Section 5 hereof,  all such  accrued and unpaid
dividends  on the  Series  A  Preferred  Stock  to and  until  the  date of such
conversion shall be forfeited and shall not be due and payable.

             (b)  Restriction  on  Distributions.  Except  to the  extent in any
instance  approval  is  provided  in writing by the holders of a majority of the
outstanding  shares of Preferred  Stock (all series acting  together as a class)
and except for any transaction  related to the Corporation's Class A Warrants or
Class B Warrants,  the  Corporation  shall not declare or pay any dividends,  or
purchase,  redeem,  retire,  or  otherwise  acquire  for value any shares of its
capital  stock (or rights,  options or warrants to purchase  such shares) now or
hereafter  outstanding,  return any capital to its stockholders as such, or make
any distributions of assets to its stockholders as such;  provided,  however, if
any such action is effected  with respect to the  Preferred  Stock,  it shall be
done  proportionately  equivalent  for the holders of all series of  outstanding
Preferred Stock.

             Nothing herein  contained shall prevent the  Corporation  from: (i)
effecting a stock split or declaring or paying any dividend consisting of shares
of any class of  capital  stock  paid to the  holders of shares of such class of
capital stock; or (ii) complying with any specific provision of the terms of the
Preferred Stock.

             (c)  Participating  Dividends.  In the  event  that  the  Board  of
Directors  of the  Corporation  shall  declare a dividend  payable upon the then
outstanding  shares of Common Stock  (other than a stock  dividend on the Common
Stock distributed  solely in the form of additional shares of Common Stock), the
holders of the Preferred Stock shall be entitled,  in addition to any cumulative
dividends to which they may be entitled under Section 2(a) hereof, to the amount
of dividends  per share of Preferred  Stock as would be declared  payable on the
largest  number  of whole  shares of  Common  Stock  into  which  each  share of
Preferred  Stock held by each holder thereof could be converted  pursuant to the
provisions of Section 5 hereof, such number determined as

                                       2
<PAGE>
                                   Page - 17


of the record date for the determination of holders of Common Stock entitled to
receive such dividend, less any dividends theretofore paid under Section 2(a)
above.

         3.  Liquidation, Dissolution or Winding Up.

             (a)  Treatment at  Liquidation,  Dissolution  or Winding Up. In the
event of any liquidation,  dissolution or winding up of the Corporation, whether
voluntary  or  involuntary,  or in the  event  of  its  insolvency,  before  any
distribution  or  payment is made to any  holders  of Common  Stock or any other
class or series of capital stock of the  Corporation  designated to be junior to
the Preferred  Stock,  and subject to the liquidation  rights and preferences of
any class or series of Preferred Stock designated in the future to be senior to,
or on a parity with,  the Series A Preferred  Stock with respect to  liquidation
preferences,  the holders of each share of Preferred  Stock shall be entitled to
be paid first out of the assets of the Corporation available for distribution to
holders of the Corporation's  capital stock of all classes,  whether such assets
are capital, surplus or earnings, an amount equal to the greater of:

                  (i) $1.125  per share of Series A  Preferred  Stock,  plus all
                  accrued but unpaid cumulative  dividends  thereon,  whether or
                  not earned or declared, or

                  (ii) such  amount per share of  Preferred  Stock as would have
                  been  payable had each such share of each series of  Preferred
                  Stock been converted to Common Stock immediately prior to such
                  event of  liquidation,  dissolution  or winding up pursuant to
                  the provisions of Section 5 hereof.

             The  amounts  set  forth  above  shall  be  subject  to   equitable
adjustment   whenever  there  shall  occur  a  stock   dividend,   stock  split,
combination, reorganization, recapitalization, reclassification or other similar
event involving a change in the capital structure of the Preferred Stock.

             If, upon liquidation, dissolution or winding up of the Corporation,
the assets of the Corporation  available for  distribution  to its  stockholders
shall be insufficient to pay the holders of all outstanding  series of Preferred
Stock the full amounts to which they otherwise would be entitled, the holders of
all outstanding  series of Preferred Stock (which is deemed for purposes of this
Section  3 to be on a  parity)  shall  share  ratably  in  any  distribution  of
available assets pro rata in proportion to the respective liquidation preference
amounts which would  otherwise be payable upon  liquidation  with respect to the
outstanding  shares of  Preferred  Stock if all  liquidation  preference  dollar
amounts with respect to such shares were paid in full,  based upon the aggregate
liquidation preference dollar amounts payable upon all shares of Preferred Stock
then outstanding (the "Liquidation Formula").

                                       3
<PAGE>
                                   Page - 18


             After such  payment  shall have been made in full to the holders of
the  Preferred  Stock,  or funds  necessary for such payment shall have been set
aside by the  Corporation  in trust for the account of holders of the  Preferred
Stock so as to be available for such payment, the remaining assets available for
distribution shall be distributed ratably among the holders of the Common Stock.

             (b)  Distributions  Other  than  Cash.  Whenever  the  distribution
provided for in this Section shall be payable in property  other than cash,  the
value of such  distribution  shall be the fair market value of such  property as
determined  in good  faith by the Board of  Directors  of the  Corporation.  All
distributions  (including distributions other than cash) made hereunder shall be
made  pro  rata to each  series  of  Preferred  Stock  in  accordance  with  the
Liquidation Formula described in Section 3(a) above. In the event of any dispute
between the holders of the  Preferred  Stock and the  Corporation  regarding the
determination  of the  fair  market  value  of  non-cash  distributions,  at the
election  of the holders of a majority of the  outstanding  shares of  Preferred
Stock,  the  Corporation  shall engage a consulting or  investment  banking firm
selected by the Board of Directors  and approved by the holders of a majority of
the outstanding shares of Preferred Stock to prepare an independent appraisal of
the  fair  market  value  of  such  property  to be  distributed.  Each  of  the
Corporation and the holders of a majority of the outstanding shares of Preferred
Stock shall provide such approved  appraiser with a written estimate of the fair
market  value of such  property,  and the  expenses of any  appraisal  by such a
consulting  or  investment  banking  firm shall be borne by the party  whose own
written  estimate of fair market value  proves to be furthest  from that of such
consulting or investment  banking firm. In the event that the parties' estimates
of fair market value differ from that of the  consulting or  investment  banking
firm by an equal amount, then the Corporation,  on the one hand, and the holders
of the Preferred Stock, on the other, shall each pay fifty percent (50%) of such
expenses.

         4.  Voting Power

         Except as otherwise  expressly  provided in this Section 4 or Section 6
hereof or as otherwise  required by law, each holder of Series A Preferred Stock
shall be entitled to vote on all matters and shall be entitled to that number of
votes equal to the  largest  number of whole  shares of Common  Stock into which
such holder's shares of Series A Preferred Stock could be converted, pursuant to
the provisions of Section 5 hereof,  at the record date for the determination of
stockholders  entitled  to vote on such  matter  or, if no such  record  date is
established,  at the  date  such  vote  is  taken  or  any  written  consent  of
stockholders  is  solicited.  Except as  otherwise  expressly  provided  in this
instruments,  the  Certificate of  Designations,  Preferences  and Rights of any
other series of outstanding Preferred Stock or as otherwise required by law, the
holders of shares of Preferred  Stock and Common  Stock shall vote  together (or
render  written  consents  in lieu of a vote) as a single  class on all  matters
submitted to the stockholders of the Corporation.

                                       4
<PAGE>
                                   Page - 19


         5.  Conversion  Rights.  The holders of the Series A Preferred Stock
shall have the following  rights with respect to the conversion of such shares
into shares of Class A Common Stock:

             (a) General.  Subject to and in compliance  with the  provisions of
this Section 5, any shares of the Series A Preferred Stock may, at the option of
any holder,  be converted at any time and from time to time into  fully-paid and
non-assessable  shares of Class A Common Stock.  The number of shares of Class A
Common  Stock  which a holder of Series A  Preferred  Stock shall be entitled to
receive  upon  conversion  shall be the  product  obtained  by  multiplying  the
Applicable  Conversion  Rate  (determined  as provided  in Section  5(b)) by the
number of shares of Series A Preferred Stock being converted at any time.

             (b) Applicable  Conversion  Rate. The conversion  rate in effect at
any time for the Series A Preferred  Stock (the  "Applicable  Conversion  Rate")
shall be the  quotient  obtained by dividing  $1.125 by the Series A  Applicable
Conversion  Value,  calculated  as  provided  in  Section  5(c)  (the  "Series A
Applicable Conversion Rate").

             (c) Applicable Conversion Value. The Series A Applicable Conversion
Value in effect from time to time, except as adjusted in accordance with Section
5(d) hereof,  shall be $1.125 with respect to the Series A Preferred  Stock (the
"Series A Applicable Conversion Value").

             (d)  Adjustments to Series A Applicable Conversion Value.

                  (i) Closing Bid Price.  At any time after August 14, 1997,  if
at the time of conversion the average Closing Bid Price (as hereinafter defined)
of the Class A Common Stock of the  Corporation  for the  immediately  preceding
twenty (20)  consecutive  trading days (the  "Twenty-Day  Average") is below the
Series  A  Applicable  Conversion  Value  then in  effect,  then  the  Series  A
Applicable  Conversion  Value relevant only for the shares of Series A Preferred
Stock being then converted shall automatically be adjusted  immediately prior to
conversion to equal 83.33% of the Twenty-Day Average.  The preceding  adjustment
to the Series A Applicable  Conversion  Value  relevant to the shares being then
converted  shall  not  adjust  or  otherwise  effect  the  Series  A  Applicable
Conversion  Value of the  remaining  outstanding  shares of  Series A  Preferred
Stock.

                  The  "Closing  Bid Price" shall mean (1) if the Class A Common
Stock is then listed on any  national  securities  exchange,  the closing  sales
price on the principal  national  securities  exchange on which it is so traded,
(2) if the Class A Common  Stock is not then  listed on any such  exchange,  the
closing  bid  price on the  over-the-counter  market  as  reported  by  NASDAQ's
National Market System or Small Capitalization System ("NASDAQ"),  or (3) if the
Class A Common  Stock is not then  listed  on any such  exchange  or  quoted  in
NASDAQ, the average of the closing bids on the National Daily Quotation Service.
If for any trading day the Class A Common Stock is listed on

                                       5
<PAGE>
                                   Page - 20


any such  exchange, or quoted in NASDAQ or National Daily Quotation Service and
the actual Closing Bid Price is not determinable in accordance with the  above,
then for such trading day the Closing Bid Price shall be the last immediately
reported Closing Bid Price.  If the Class A Common Stock is not listed on any
such  exchange, or quoted in NASDAQ or  National  Daily  Quotation  Service, the
Closing Bid Price shall be determined in good faith by the Board of Directors of
the Corporation.

                  (ii) Upon Extraordinary Common Stock Event.  Upon the
 happening of an  Extraordinary
Common Stock Event (as hereinafter defined),  the Series A Applicable Conversion
Value shall,  simultaneously  with the  happening of such  Extraordinary  Common
Stock Event, be adjusted by multiplying the Series A Applicable Conversion Value
by a fraction,  the  numerator  of which shall be the number of shares of Common
Stock outstanding immediately prior to such Extraordinary Common Stock Event and
the  denominator  of  which  shall be the  number  of  shares  of  Common  Stock
outstanding  immediately  after such  Extraordinary  Common Stock Event, and the
product so  obtained  shall  thereafter  be the Series A  Applicable  Conversion
Value.  The Series A  Applicable  Conversion  Value,  as so  adjusted,  shall be
readjusted in the same manner upon the happening of any successive Extraordinary
Common Stock Event or Events.

             An  "Extraordinary  Common Stock Event" shall mean (I) the issue of
additional  shares  of  Common  Stock as a  dividend  or other  distribution  on
outstanding  shares of Common Stock, (ii) a subdivision of outstanding shares of
Common  Stock  into a greater  number of  shares  of  Common  Stock,  or (iii) a
combination or reverse stock split of outstanding  shares of Common Stock into a
smaller number of shares of the Common Stock.

             (e)  Automatic Conversion.

                  (i) Mandatory  Conversion of Preferred  Stock.  Immediately
  upon (1) the  effectiveness
of an underwritten  public  offering on a firm  commitment  basis pursuant to an
effective  registration  statement filed pursuant to the Securities Act of 1933,
as amended,  covering  the offer and sale of Common Stock for the account of the
Corporation in which the Corporation  actually  receives gross proceeds equal to
or greater than $5,000,000 (calculated after deducting  underwriters'  discounts
and commissions but before calculation of expenses),  and in which the price per
share of Common Stock equals or exceeds  $3.00 (such price  subject to equitable
adjustment  in the  event  of any  stock  dividend,  stock  split,  combination,
reorganization,  recapitalization,   reclassification  or  other  similar  event
involving  a change  in the  Common  Stock),  (2) the  approval,  set forth in a
written notice to the Corporation,  of the holders of at least a majority of the
outstanding  shares of Series A Preferred Stock of an election to convert Series
A Preferred  Stock into Class A Common Stock,  or (3) August 14, 2001,  then all
outstanding shares of Series A Preferred Stock shall be converted  automatically
into the number of shares of Class A Common  Stock  into  which  such  shares of
Series A Preferred Stock are then convertible pursuant to Section 5

                                       6
<PAGE>
                                   Page - 21


hereof as of the closing and consummation of such underwritten  public offering,
the stated date of approval of such holders of Series A Preferred Stock or
August 14, 2001, without any further action by the holders of such shares and
whether or not the certificates  representing such shares are surrendered to the
Corporation or its transfer agent.

                  (ii)     Surrender of Certificates Upon Mandatory Conversion.
  Upon the occurrence of
the conversion  events specified in the preceding  paragraph (i), the holders of
the Series A Preferred Stock shall, upon notice from the Corporation,  surrender
the certificates representing such shares at the office of the Corporation or of
its transfer  agent for the Common Stock.  Thereupon,  there shall be issued and
delivered to such holder a certificate or certificates  for the number of shares
of Class A Common  Stock into which the  shares of Series A  Preferred  Stock so
surrendered were convertible on the date on which such conversion occurred.  The
Corporation   shall  not  be  obligated  to  issue  such   certificates   unless
certificates  evidencing the shares of Series A Preferred  Stock being converted
are either  delivered to the  Corporation  or any such  transfer  agent,  or the
holder notifies the Corporation that such certificates have been lost, stolen or
destroyed and executes an agreement satisfactory to the Corporation to indemnify
the Corporation from any loss incurred by it in connection therewith.

             (f) Dividends. In the event the Corporation shall make or issue, or
shall  fix a record  date for the  determination  of  holders  of  Common  Stock
entitled to receive a dividend or other distribution  (other than a distribution
in liquidation or other distribution otherwise provided for herein) with respect
to the Common Stock  payable in (i)  securities  of the  Corporation  other than
shares of Common  Stock,  or (ii) other  assets  (excluding  cash  dividends  or
distributions),  then and in each such event provision shall be made so that the
holders of the Series A Preferred Stock shall receive upon conversion thereof in
addition  to the  number of shares of Common  Stock  receivable  thereupon,  the
number of  securities or such other assets of the  Corporation  which they would
have  received had their  Series A Preferred  Stock been  converted  into Common
Stock on the date of such event and had they thereafter,  during the period from
the date of such event to and  including  the  Conversion  Date (as that term is
hereafter  defined in Section  5(j)),  retained  such  securities  or such other
assets  receivable by them during such period,  giving  application to all other
adjustments  called for during such period  under this Section 5 with respect to
the rights of the holders of the Series A Preferred Stock.

             (g) Capital Reorganization or Reclassification. If the Common Stock
issuable upon the  conversion  of the Series A Preferred  Stock shall be changed
into the same or  different  number of shares of any class or classes of capital
stock, whether by capital reorganization, recapitalization,  reclassification or
otherwise  (other than a subdivision  or combination of shares or stock dividend
provided for  elsewhere  in this Section 5, or the sale of all or  substantially
all of the Corporation's  capital stock or assets to any other person), than and
in each such event the holder of each share of

                                       7
<PAGE>
                                   Page - 22


Series A Preferred  Stock shall have the right  thereafter to convert such share
into the kind and amount of shares of capital  stock and other  securities  and
property receivable upon such reorganization, recapitalization, reclassification
or other change by the holders of the number of shares of Common Stock into
which such shares of Series A Preferred Stock might have been converted
immediately  prior to  such  reorganization,  recapitalization, reclassification
or  change,  all subject to further adjustment as provided herein.

             (h)  Capital  Reorganization,  Merger or Sale of Assets.  If at any
time or from time to time there shall be a capital  reorganization of the Common
Stock (other than a subdivision, combination, recapitalization, reclassification
or exchange of shares  provided for  elsewhere in this Section 5) or a merger or
consolidation of the Corporation with or into another  corporation (other than a
merger or  reorganization  involving only a change in the state of incorporation
of the  Corporation or the  acquisition by the  Corporation of another  business
where the  Corporation  survives  as a going  concern,  as further  provided  in
Section 3 hereof),  or the sale of all or substantially all of the Corporation's
capital  stock  or  assets  to  any  other  person,  then,  as a  part  of  such
reorganization,  merger,  or consolidation  or sale,  provision shall be made so
that the holders of the Series A Preferred Stock shall thereafter be entitled to
receive upon  conversion of the Series A Preferred Stock the number of shares of
stock or other securities or property (including cash) of the Corporation, or of
the successor corporation resulting from such merger,  consolidation or sale, to
which such holder  would have been  entitled if such  holder had  converted  its
shares  of  Series  A  Preferred  Stock   immediately   prior  to  such  capital
reorganization,  merger,  consolidation  or sale. In any such case,  appropriate
adjustment  shall be made in the application of the provisions of this Section 5
to the end that the  provisions  of this Section 5 (including  adjustment of the
Series A Applicable  Conversion Value then in effect and the number of shares of
Common Stock or other  securities  issuable  upon  conversion  of such shares of
Series A  Preferred  Stock)  shall be  applicable  after that event in as nearly
equivalent a manner as may be practicable.

             The  holders of at least a majority  of the  outstanding  shares of
Preferred  Stock,  upon the  occurrence of a capital  reorganization,  merger or
consolidation  of the Corporation,  or the sale of all or substantially  all its
capital  stock or assets,  as such  events are more fully set forth in the first
paragraph of this Section 5(h), shall have the option of electing  treatment for
the  Preferred  Stock as would be required for an event covered under either (i)
this Section 5(h) or (ii) Section 3 hereof regard a liquidation,  dissolution or
winding up of the affairs of the Corporation,  notice of which election shall be
submitted in writing to the  Corporation  at its principal  office no later than
twenty (20) business days before the effective date of such event.

             (i) Certificate as to Adjustments;  Notice by Corporation.  In each
case of an  adjustment  or  readjustment  of the Series A Applicable  Conversion
Rate,  the  Corporation  at its  expense  will  furnish  each holder of Series A
Preferred  Stock so affected  with a  certificate  prepared by the  Treasurer or
Chief Financial Officer of the

                                       8
<PAGE>
                                   Page - 23


Corporation, showing such adjustment or readjustment, and stating in detail the
facts  upon which such  adjustment  or readjustment is based.

             (j) Exercise of Conversion  Privilege.  To exercise its  conversion
privilege,  a holder of Series A Preferred Stock shall surrender the certificate
or  certificates  representing  the shares being converted to the Corporation at
its principal  office,  and shall give written notice to the Corporation at that
office that such holder  elects to convert such  shares.  Such notice shall also
state the name or names (with address or addresses) in which the  certificate or
certificates  for shares of Class A Common Stock  issuable upon such  conversion
shall be  issued.  The  certificate  or  certificates  for  shares  of  Series A
Preferred  Stock  surrendered  for  conversion  shall be  accompanied  by proper
assignment  thereof to the  Corporation or in blank.  The date when such written
notice  is  received  by the  Corporation,  together  with  the  certificate  or
certificates   representing  the  shares  of  Series  A  Preferred  Stock  being
converted,  shall be the "Conversion Date". As promptly as practicable after the
Conversion Date, the Corporation  shall issue and shall deliver to the holder of
the shares of Series A Preferred Stock being converted, or on its written order,
such  certificate  or  certificates  as it may  request  for the number of whole
shares of Class A Common Stock  issuable  upon the  conversion of such shares of
Series A Preferred  Stock in accordance  with the  provisions of this Section 5,
and cash,  as provided in Section 5(k), in respect of any fraction of a share of
Class A Common Stock issuable upon such  conversion.  Such  conversion  shall be
deemed to have been effected  immediately  prior to the close of business on the
Conversion  Date,  and at such time the  rights  of the  holder as holder of the
converted  shares of Series A Preferred  Stock shall cease and the  person(s) in
whose  name(s) any  certificate(s)  for shares of Class A Common  Stock shall be
issuable  upon such  conversion  shall be deemed to have  become  the  holder or
holders of record of the shares of Class A Common Stock represented thereby.

             (k) Cash in Lieu of  Fractional  Shares.  No  fractional  shares of
Class A Common  Stock or scrip  representing  fractional  shares shall be issued
upon the  conversion  of shares  of Series A  Preferred  Stock.  Instead  of any
fractional shares of Class A Common Stock which would otherwise be issuable upon
conversion of Series A Preferred Stock, the Corporation  shall pay to the holder
of the shares of Series A Preferred Stock which were converted a cash adjustment
in respect of such fractional  shares in an amount equal to the same fraction of
the  market  price  per share of the Class A Common  Stock (as  determined  in a
reasonable manner prescribed by the Board of Directors) at the close of business
on the Conversion  Date. The  determination  as to whether or not any fractional
shares are issuable shall be based upon the aggregate number of shares of Series
A Preferred  Stock being  converted at any one time by any holder  thereof,  not
upon each share of Series A Preferred Stock being converted.

                                       9
<PAGE>
                                   Page - 24


             (l) Partial Conversion. In the event some but not all of the shares
of Series A Preferred  Stock  represented by a  certificate(s)  surrendered by a
holder are  converted,  the  Corporation  shall execute and deliver to or on the
order of the  holder,  at the  expense  of the  Corporation,  a new  certificate
representing  the number of shares of Series A  Preferred  Stock  which were not
converted.

             (m) Reservation of Common Stock. The Corporation shall at all times
reserve and keep available out of its authorized but unissued  shares of Class A
Common Stock,  solely for the purpose of effecting the  conversion of the shares
of the Series A  Preferred  Stock,  such  number of its shares of Class A Common
Stock as shall from time to time be sufficient  to effect the  conversion of all
outstanding  shares of the Series A  Preferred  Stock  (including  any shares of
Series A Preferred Stock represented by any warrants,  options,  subscription or
purchase rights for Series A Preferred Stock),  and if at any time the number of
authorized  but unissued  shares of Class A Common Stock shall not be sufficient
to  effect  the  conversion  of all  then  outstanding  shares  of the  Series A
Preferred Stock (including any shares of Series A Preferred Stock represented by
any  warrants,  options,  subscriptions  or  purchase  rights for such  Series A
Preferred Stock),  the Corporation shall take such action as may be necessary to
increase  its  authorized  but  unissued  shares of Class A Common Stock to such
number of shares as shall be sufficient for such purpose.

             (n) Reissuance of Preferred  Stock.  No share or shares of Series A
Preferred Stock acquired by the  Corporation by reason of redemption,  purchase,
conversion or otherwise shall be reissued as Series A Preferred  Stock,  but all
such shares shall be  considered  authorized  but  unissued  shares of Preferred
Stock.

         6.  Restrictions and Limitations.

             (a) Corporate Action;  Amendments to Charter. The Corporation shall
not  take  any  corporate   action  or  otherwise   amend  its   Certificate  of
Incorporation  without the approval by vote or written consent of the holders of
at least a majority of the then outstanding  shares of Preferred  Stock,  voting
together as a single class,  each share of Preferred Stock to be entitled to one
vote in each instance,  if such corporate  action or amendment would  materially
adversely  affect any of the rights,  preferences,  privileges of or limitations
provided  for  herein  for the  benefit  of any  shares  of  Preferred  Stock or
otherwise materially adversely affect the rights of the holders of the Preferred
Stock.   Without  limiting  the  generality  of  the  preceding  sentence,   the
Corporation  will not amend its Certificate of  Incorporation  or take any other
corporate  action  without the approval by the holders of at least a majority of
the then  outstanding  shares of Preferred  Stock,  voting  together as a single
class, if such amendment or corporate action would:

                                       10
<PAGE>
                                   Page - 25


                           (i) authorize or issue,  or obligate the  Corporation
                           to authorize or issue, additional shares of Preferred
                           Stock  senior  to or on a parity  with the  Preferred
                           Stock  with  respect  to   liquidation   preferences,
                           dividend rights or redemption rights,  except for the
                           designation and issuance of shares of Preferred Stock
                           approved in any instance by the holders of a majority
                           of the outstanding shares of Preferred Stock; or

                           (ii)  reduce  the amount  payable  to the  holders of
                           Preferred  Stock upon the  voluntary  or  involuntary
                           liquidation,   dissolution   or  winding  up  of  the
                           Corporation; or

                           (iii) adversely  affect the liquidation  preferences,
                           dividend rights,  voting rights or redemption  rights
                           of the holders of Preferred Stock; or

                           (iv) cancel or adversely modify the conversion rights
                           of the holders of  Preferred  Stock  provided  for in
                           Section 5 herein.

         7. No Dilution or Impairment. The Corporation will not, by amendment of
its  Certificate of  Incorporation  or through any  reorganization,  transfer of
capital stock or assets,  consolidation,  merger, dissolution,  issue or sale of
securities or any other voluntary action,  avoid or seek to avoid the observance
or performance of any of the terms of the Preferred Stock set forth herein,  but
will at all times in good faith assist in the carrying out of all such terms and
in the taking of all such action as may be necessary or  appropriate in order to
protect the rights of the holders of the  Preferred  Stock  against  dilution or
other  impairment.  Without  limiting  the  generality  of  the  foregoing,  the
Corporation  (a)  will  not  increase  the par  value  of any  shares  of  stock
receivable on the  conversion of the  Preferred  Stock above the amount  payable
therefor  on such  conversion,  and (b)  will  take all  such  action  as may be
necessary or appropriate in order that the  Corporation  may validly and legally
issue  fully paid and  nonassessable  shares of stock on the  conversion  of all
Preferred Stock from time to time outstanding.

         8.  Notices of Record Date.   In the event of:

             (a) any taking by the Corporation of a record of the holders of any
class of securities for the purpose of determining  the holders  thereof who are
entitled  to  receive  any  dividend  or  other  distribution,  or any  right to
subscribe for,  purchase or otherwise acquire any shares of capital stock of any
class or any other securities or property, or to receive any other right, or

                                       11
<PAGE>
                                   Page - 26


             (b)   any   capital   reorganization   of  the   Corporation,   any
reclassification  or  recapitalization  of the capital stock of the Corporation,
any  merger or  consolidation  of the  Corporation,  or any  transfer  of all or
substantially all of the assets of the Corporation to any other corporation,  or
any other entity or person, or

             (c) any voluntary or involuntary dissolution, liquidation or
winding up of the Corporation,

then and in each such event the Corporation  shall mail or cause to be mailed to
each  holder of Series A  Preferred  Stock a notice  specifying  (i) the date on
which  any  such  record  is to be  taken  for the  purpose  of  such  dividend,
distribution or right and a description of such dividend, distribution or right,
(ii)   the   date  on   which   any   such   reorganization,   reclassification,
recapitalization,  transfer, consolidation,  merger, dissolution, liquidation or
winding up is expected to become effective,  and (iii) the time, if any, that is
to be  fixed,  as to when the  holders  of  record  of  Common  Stock  (or other
securities) shall be entitled to exchange their shares of Common Stock (or other
securities)   for   securities   or  other   property   deliverable   upon  such
reorganization,  reclassification,  recapitalization,  transfer,  consolidation,
merger,  dissolution,  liquidation or winding up. Such notice shall be mailed by
first  class  mail,  postage  prepaid,  at least ten (10) days prior to the date
specified in such notice on which such action is to be taken.


EXECUTED this 14th day of August, 1996.



                                     --------------------------------------
                   Paul C. Desjourdy, Executive Vice President
ATTEST:



- -----------------------------------
Jack H. Kessler, Secretary

                                       12
<PAGE>
                                   Page - 27


                                   Exhibit 1.2
<TABLE>

                               LIST OF PURCHASERS
<CAPTION>


                                Number of Shares
         Name of Purchaser                           to be Purchased
         ------------------                          ----------------
         <S>                                              <C>
         Anthony J. Cantone                               400,000
         Jack H. Kessler                                   44,444
                                                         --------

                  Total Shares                            444,444

</TABLE>


<PAGE>
                                   Page - 28


                                   Exhibit 4.4

                                  RISK FACTORS


         The securities  offered hereby are  speculative in nature and involve a
high degree of risk. Prior to making an investment, prospective investors should
carefully consider the following factors,  as well as others described elsewhere
in the  Disclosure  Documents,  relating to the  business of the Company and the
securities offered hereby.


Development Stage Company;  Early Stage of Product Development;  No Assurance of
Successful Product Development.  The Company is in the development stage and has
not  conducted  any  significant  operations  to date or received any  operating
revenues,  except  for  revenues  from the  sale of the  Company's  bovine  teat
sanitizer, marketed under the name IodoZyme(R), which the Company began shipping
in early 1995.  Potential  investors  should be aware of the  problems,  delays,
expenses and difficulties encountered by an enterprise in the Company's stage of
development,  many of which may be beyond the Company's control.  These include,
but are not limited to, unanticipated  problems relating to product development,
testing, regulatory compliance, manufacturing costs, production, the competitive
and  regulatory  environment  in which the Company  plans to operate,  marketing
problems and additional  costs and expenses that may exceed  current  estimates.
Products under  development by the Company will require  additional  development
and investment prior to obtaining  regulatory  approvals and  commercialization.
There can be no assurance  that such  products will be  successfully  developed,
meet  applicable  regulatory  standards,  be capable of production in commercial
quantities at reasonable costs or be successfully marketed.

Accumulated   Deficit;   Expectation  of  Future  Losses;  Need  for  Additional
Financing.  At December  31,  1995,  the Company had an  accumulated  deficit of
$4,427,664, which deficiency has increased to date. The Company will be required
to conduct  significant  research,  development  and testing  activities  which,
together with manufacturing,  and other general and administrative expenses, are
expected to result in operating losses for the foreseeable future.  There can be
no  assurance  that the Company will ever have  significant  revenues or achieve
profitable operations.  At December 31, 1995, the Company had working capital of
$2,076,966,  and while the Company  anticipates  losses for the  current  fiscal
year,  based on its current  operating  plan, the Company  believes it will have
sufficient working capital (including the net proceeds of this Offering) to fund
its  operations  through the end of the current  fiscal year. It is not expected
that the net proceeds of this Offering  together  with revenues from  operations
will be sufficient  to enable the Company to complete the  necessary  regulatory
approval process for its products  currently under  development,  or if any such
approval were obtained,  to begin  manufacturing or marketing such products on a
commercial  basis.  Given  the  Company's  limited  financial   resources,   the
uncertainty of the development effort and the necessity for regulatory approval,
there can be no  assurance  of  ultimate  success  with  respect to any  product
development program

                                       1
<PAGE>
                                   Page - 29


or  that  resulting   product,   if  any,  will  be  commercially   successful.
Additionally,  the Company's limited resources will require  substantial support
for new business areas from corporate  partners who would  ultimately  introduce
the  Company's  products  into the  marketplace.  In  addition  to support  from
corporate  partners,  the  Company  may seek  additional  financing  to fund its
operating requirements.  There can be no assurance that the Company will be able
to obtain such  partnering  arrangements  or financing,  or that such partnering
arrangements  or financing,  if available,  will be on acceptable  terms. In the
event that the Company fails to raise any funds it requires, it may be necessary
for the Company to cease operations or severely limit growth.

Lack of Marketing  Experience;  Dependence on Outside  Parties for Marketing and
Distribution;   Uncertainty  of  Market  Acceptance  of  Products  and  Proposed
Products.  The marketing and  distribution of IodoZyme is conducted by West Agro
pursuant to an exclusive  marketing and supply  agreement with the Company which
covers  IodoZyme as well as other  products  which may be  developed  for use in
dairy  facilities.  The  Company  intends to rely on similar  arrangements  with
others for the  marketing  and  distribution  of its  products  currently  under
development,  if and when  successfully  developed  and  approved by  applicable
regulatory agencies.  This results, and will result, in a lack of control by the
Company over some or all of the marketing  and  distribution  of such  products.
Although  the Company has  entered  into  development  agreements  with  parties
experienced  in the  marketing of several of the  Company's  proposed  products,
which development  agreements contemplate future marketing  arrangements,  there
can be no assurance  that the Company  will be able to enter into any  marketing
arrangements  for such products,  if and when developed,  on terms acceptable to
the Company or that any  marketing  efforts  undertaken on behalf of the Company
will be  successful.  Although  the Company  has no present  plans to do so, the
Company may, in the future, determine to directly market certain of its proposed
products.  The Company has no marketing  experience and  significant  additional
capital  expenditures  and management  resources  would be required to develop a
direct  sales  force.  In the  event  the  Company  elects  to  engage in direct
marketing  activities,  there can be no assurance that the Company would be able
to obtain  the  requisite  funds or  attract  and  retain  the  human  resources
necessary to successfully market any of such products.

         The Company's  future growth and  profitability  will depend,  in large
part, on the success of its personnel and others conducting marketing efforts on
behalf of the Company in fostering  acceptance  among the various markets of the
use of the Company's  products as an alternative to other available  products or
otherwise. The Company's success in marketing its products will be substantially
dependent   on   educating   its   targeted   markets  as  to  the   distinctive
characteristics  and  perceived  benefits  of the  Company's  products.  In this
regard, West Agro, which acts as exclusive marketer and distributor of IodoZyme,
also  markets and  distributes  products  which are  directly  competitive  with
IodoZyme. There can be no assurance that the Company's efforts or the efforts of
others  will be  successful  or that any of the  Company's  products or proposed
products will be favorably accepted among the targeted markets.

                                       2
<PAGE>
                                   Page - 30


Lack  of   Manufacturing   Experience;   Dependence   on  Outside   Parties  for
Manufacturing.  IodoZyme is currently produced through a combination of internal
manufacturing activities and a network of contract manufacturers. With regard to
its proposed products,  the Company intends to rely on similar arrangements with
others for their  manufacture.  The  Company's  dependence  on third parties for
manufacturing  may adversely affect the Company's ability to develop and deliver
products  on a timely  and  competitive  basis.  The  Company  may in the future
undertake to  manufacture  some or all of its  products  and  proposed  products
entirely in-house. Except for limited experience regarding IodoZyme, the Company
has no  experience  with the  manufacture  of any of its  products  or  proposed
products  although  certain of the  Company's  officers  have had  experience in
similar  activities for other companies.  In the event the Company  continues to
perform its  current  IodoZyme  manufacturing  activities  in-house,  additional
manufacturing space and equipment may be necessary beyond 1996 as product volume
increases.  In  addition,  in the  event  the  Company  undertakes  to  directly
manufacture  any of its  proposed  products,  the  Company  will be  required to
attract and retain experienced  personnel to develop a manufacturing  capability
and  to  comply  with  extensive  government  regulations  with  respect  to its
facilities,   including   among   others,   the  United  States  Food  and  Drug
Administration  ("FDA")  manufacturing  requirements.  There can be no assurance
that  the  Company   will  be  able  to   successfully   establish   appropriate
manufacturing operations.

Dependence  Upon,  and Need for, Key  Personnel.  The Company does not currently
have a President  or Chief  Executive  Officer.  The Company is dependent on the
services of Dr. Jack H. Kessler, the Executive Vice President,  Chief Scientific
Officer,  Secretary and a director and principal stockholder of the Company, and
Paul C. Desjourdy,  the Executive Vice  President-Finance and Administration and
Chief Financial  Officer of the Company.  The loss of either of such individuals
or a reduction  in the time devoted by such  persons to the  Company's  business
could have a material adverse effect on the Company's business.  The Company has
obtained key-person life insurance coverage in the face amount of $1,000,000 for
Dr. Kessler naming the Company as beneficiary  under such policy.  The Company's
success  also will depend,  in large part,  on its ability to attract and retain
highly  qualified  scientific and business  personnel,  competition for which is
intense.  There can be no assurance that the Company will be able to attract and
retain the necessary personnel to implement its business plan.

Intense  Competition and Rapid  Technological  Change. The Company is engaged in
rapidly  evolving  and  highly  competitive  fields.  There are many  companies,
including large pharmaceutical and chemical companies,  which have established a
significant  presence in the markets which the  Company's  products and proposed
products are designed to address.  Most of these  companies  have  substantially
greater  capital  resources,  research and  development  staffs,  facilities and
experience in obtaining regulatory  approvals,  as well as in the manufacturing,
marketing  and  distribution  of  products,  than the  Company.  There can be no
assurance  that  the  Company's  competitors  will  not  succeed  in  developing
technologies  and  products  that are more  effective  and less  costly than any
products

                                       3
<PAGE>
                                   Page - 31


developed or being  developed by the Company or which could render the Company's
microbicide technology obsolete.

Uncertain  Protection of Patents and Proprietary  Rights.  The Company considers
patent  protection of its  technology to be critical to its business  prospects.
There can be no assurance that the Company's  pending patent  applications  will
issue as  patents,  that any  issued  patents  will  provide  the  Company  with
significant  competitive  advantages,  or that challenges will not be instituted
against the validity or enforceability of any patent owned by the Company or, if
instituted,  that such challenges will not be successful. The cost of litigation
to uphold the validity and prevent  infringement  of patents can be substantial.
Furthermore,  there  can be no  assurance  that  others  will not  independently
develop  similar or more advanced  technologies  or design around aspects of the
Company's  technology  which may be patented,  or duplicate the Company's  trade
secrets.  In some cases,  the  Company may rely on trade  secrets to protect its
innovations.  There can be no assurance that trade secrets will be  established,
or  that  secrecy   obligations  will  be  honored,  or  that  others  will  not
independently  develop  similar  or  superior  technology.  To the  extent  that
consultants,   key  employees  or  other  third   parties  apply   technological
information  independently  developed by them or by others to Company  projects,
disputes may arise as to the proprietary  rights to such  information  which may
not be resolved in favor of the Company.

Governmental Regulation and Uncertainty of Product Approvals. The production and
marketing  of the  Company's  products  and  proposed  products  are  subject to
extensive regulation by Federal and state governmental authorities in the United
States  and in  foreign  countries  where  such  products  may be  produced  and
marketed.   In  the  United  States,   the  FDA  regulates,   where  applicable,
development,  testing,  labeling,  manufacturing,   registration,  notification,
clearance or approval,  marketing,  distribution,  recordkeeping  and  reporting
requirements for human and animal drugs, medical devices,  biologies,  cosmetics
and   food   additives.   The   Company's   proposed   products,   including   a
disinfectant/sterilant for medical instruments and an antimicrobial handwash and
handcream  will  require FDA  clearance  prior to  marketing.  Teat  sanitizers,
although  considered animal drugs by the FDA, do not currently require clearance
by the FDA prior to  marketing.  The FDA,  however,  has  recently  issued draft
voluntary  guidelines  governing  teat  dips and no  assurance  can be made that
clearance  by the FDA will not be required in the  future.  Required  compliance
with these guidelines or other FDA requirements, the probability of which cannot
currently be ascertained by the Company, would have a significant adverse effect
on the marketing of IodoZyme  and,  consequently,  on the  Company's  results of
operations.  The Federal Environmental Protection Agency ("EPA") has regulations
covering many of the same areas for many of the Company's  products and proposed
products. In addition,  the United States Department of Agriculture ("USDA") may
regulate,  on either a voluntary or mandatory basis,  products which the Company
may develop for sanitizing food or food contact  surfaces.  Comparable state and
local agencies may have similar regulations. The FDA and EPA regulatory approval
processes may take a number of years and require the  expenditure of substantial
resources. There can be no assurance that the production and marketing of the

                                       4
<PAGE>
                                   Page - 32


Company's  products or other  products  which may be developed by the Company in
the future,  if any, will satisfy the current  requirements of the FDA or EPA or
comparable  state  and  foreign  authorities  or  that  the  Company  will  have
sufficient funds to complete the regulatory approval process. In addition, there
can be no assurance  that  government  regulations  applicable  to the Company's
products and proposed products or the interpretation thereof will not change and
thereby  prevent the Company  from  marketing  some or all of its products for a
period of time or  permanently.  The  Company is unable to predict the extent of
adverse governmental  regulation which might arise from future Federal, state or
foreign legislative or administrative action.

Materials  Incompatibility.  An important  aspect of the  Company's  present and
future  microbicides  is that they must be compatible with the surfaces on which
they come in contact.  The Company has ceased  efforts to develop a  microbicide
for  dental  handpieces  and renal  control  units as a result of  staining  and
corrosion  caused by  required  microbicide  formulations,  and the  Company has
encountered  problems of staining  in  connection  with its efforts to develop a
high level  disinfectant  for  flexible  endoscopes.  The Company  continues  to
investigate the balance between the level of microbicidal  efficacy and the need
to avoid  staining and  corrosion.  For any proposed  inanimate  object  product
applications,  staining or corrosion  from a microbicide  could be sufficient to
limit or  forestall  regulatory  approval of such  microbicide  or, if approved,
could adversely affect market  acceptance of such  microbicide.  There can be no
assurance  that the Company will be  successful  in  overcoming  any problems of
materials incompatibility.

Potential  Product  Liability  and  Lack  or  Insufficiency  of  Insurance.  The
Company's business will expose it to potential product liability risks which are
inherent  in the  testing,  manufacturing,  marketing  and  sale of  microbicide
products for animal and human use. If  available,  product  liability  insurance
generally is expensive. The Company currently has product liability insurance in
amounts  that  it  believes  are  adequate  to  protect  it  against   potential
liabilities.  However,  there  can be no  assurance  to such  effect or that the
Company will be able to maintain  such  insurance on  acceptance  terms.  In the
event of a  successful  suit  against the Company,  a lack or  insufficiency  of
insurance  coverage  could  have a  material  adverse  effect  on the  Company's
business and operations.

Charge  to Income  in the  Event of  Release  of  Restrictions  on  Shares.  The
Commission has recently adopted a position with respect to arrangements  such as
the  one  entered   into  among  the  Company  and  all  Class  B  Common  Stock
Stockholders.  This position provides that, in the event any shares are released
from the  restrictions of the kind applicable to the stockholders of the Company
who  are  officers,   directors,   consultants  or  employees  of  the  Company,
compensation   expense  will  be  recorded  for  financial  reporting  purposes.
Therefore,  in the event the Company attains certain earnings  thresholds or the
Company's Class A Common Stock meets certain minimum bid prices required for the
release of the restrictions, such release will be deemed additional compensation
expense  of the  Company.  (See  "Note  E -  Capitalization"  to  the  Company's
Financial  Statements set forth in the Annual Report on Form 10-KSB for the year
ended  December 31,  1995.)  Accordingly,  the Company will, in the event of the
release of the restrictions, recognize

                                       5
<PAGE>
                                   Page - 33


during the period in which the earnings thresholds  are met or such  minimum bid
prices  obtained,  what  could  be a substantial  one-time  charge  which  would
have the  effect  of  substantially increasing the Company's loss or reducing or
eliminating  earnings, if any, at such time. Although the amount of compensation
expense recognized by the Company will not affect the Company's total
stockholders' equity, it may have a depressive effect on the market price of the
Company's securities.

Possible  Adverse Effects of  Authorization  of Preferred  Stock.  The Company's
Certificate  of  Incorporation  authorizes  the issuance of 5,000,000  shares of
preferred  stock on terms which may be fixed by the Company's Board of Directors
without further  stockholder action. The terms of any series of preferred stock,
which may include  priority  claims to assets and dividends,  and special voting
rights,  could  adversely  affect  the  rights of  holders of the Class A Common
Stock. No preferred stock has been issued to date and the Company has no current
plans to issue such  preferred  stock  other than as  contemplated  herein.  The
issuance of such preferred stock could make the possible takeover of the Company
or the removal of management of the Company more difficult,  discourage  hostile
bids for control of the Company in which  stockholders  may receive premiums for
their shares of Class A Common Stock, or otherwise  dilute the rights of holders
of Class A Common Stock and the market price of the Class A Common Stock.

Control by Class B  Stockholders;  Ownership of Shares  Having  Disproportionate
Voting Rights; Possible Depressive Effect on the Company's Securities. There are
currently  1,199,713  shares of Class B Common Stock  outstanding,  representing
approximately 48% of the outstanding  capital stock and approximately 82% of the
total voting power of the  outstanding  Class A and Class B Common  Stock.  As a
result,  the  Company's  Class  B  Stockholders  are  able to  elect  all of the
Company's  directors and otherwise  control the Company's  operations.  Officers
and/or  directors  of the  Company  beneficially  own  approximately  90% of the
outstanding shares of Class B Common Stock.  Furthermore,  the  disproportionate
vote  afforded  the Class B Common Stock could also serve to impede or prevent a
change of  control  of the  Company.  As a result,  potential  acquirers  may be
discouraged  from seeking to acquire control of the Company through the purchase
of Class A Common  Stock,  which could have a depressive  effect on the price of
the Company's securities.

Arbitrary  Determination of Offering Price;  Possible Volatility of Stock Price.
The  conversion  price and other  terms of the Shares  have been  determined  by
negotiation  between the  Company and the  Purchasers  in  connection  with this
Offering and are not related to the Company's asset value,  net worth or results
of  operations.  The market prices for  securities  of emerging and  development
stage companies in general, and biopharmaceutical  companies in particular, have
historically been highly volatile.  Future announcements  concerning the Company
or its competitors,  including the results of testing, technological innovations
or new commercial  products,  government  regulations,  developments  concerning
proprietary  rights,  litigation  or public  concern  as to  safety of  products
developed by the Company or others, may have a significant adverse impact on the
market price of the Company's securities.

                                       6
<PAGE>
                                   Page - 34


Possible  Delisting of  Securities  from the NASDAQ  System and Possible  Market
Illiquidity.  There can be no assurance  that the Company will meet the criteria
for  continued  listing  of  securities  on  NASDAQ  or for use of the  Form S-3
registration  statement  under  the  Securities  Act.  In order to  qualify  for
continued listing on the NASDAQ System, a company must, among other things, have
at least  $2,000,000  in total  assets,  $1,000,000  in capital and  surplus,  a
minimum bid price of $1.00 per share of common stock,  and 100,000 shares in the
public float.  In addition,  the common stock must have at least two  registered
and active market makers and must be held by at least 300 holders and the market
value of its public float must be at least $200,000.  If an issuer does not meet
the $1.00 minimum bid price standard,  it may, however,  remain in NASDAQ if the
market  value of its  public  float is at least  $1,000,000  and the  issuer has
capital and surplus of at least $2,000,000.  At December 31, 1995, the Company's
balance sheet  reflects  total assets of  $2,485,545  and capital and surplus of
$2,307,555.  If the Company  should become unable to meet the continued  listing
criteria of NASDAQ and is delisted  therefrom,  trading,  if any, in the Class A
Common Stock would thereafter be conducted in the over-the-counter market in the
so-called "pink sheets" or, if then available, the "OTC Bulletin Board Service."
As a result,  an investor  would likely find it more difficult to dispose of, or
to obtain accurate quotations as to the value of, the Company's  securities.  If
the Company's  securities were delisted from NASDAQ,  they may become subject to
penny stock restrictions.  If the Company's securities were subject to the rules
on penny stocks,  the market  liquidity for the  Company's  securities  could be
severely adversely affected.

Immediate and Substantial Dilution. Assuming exercise of all outstanding Class A
and Class B Warrants  and  conversion  of all of the  Preferred  Shares  offered
hereby the Purchasers  will  experience  substantial  dilution.  The outstanding
Warrants have anti-dilution  protections for their holders.  This Offering could
trigger substantial anti-dilution adjustments under such other instruments.

No  Registration.  The Shares  and the Common  Stock  issuable  upon  conversion
thereof have not been  registered  under the  Securities Act of 1933, as amended
(the "Act") or any  applicable  state  securities  laws  ("State  Acts").  These
securities  may not be  offered,  sold of  otherwise  transferred  in the United
States or to U.S. persons unless the securities are registered under the Act and
applicable  State Acts or such offers,  sales and transfers are made pursuant to
an  available  exemption  from the  registration  requirements  of  those  laws.
Pursuant  to the Stock  Purchase  Agreement,  the  Purchasers  will agree not to
transfer any  securities  except in compliance  with all  Applicable  Securities
Laws.  Although the Company has  undertaken  to use its best efforts to effect a
registration  of the  Class A  Common  Stock  issuable  upon  conversion  of the
Preferred Shares and purchased at the Second Closing,  there can be no assurance
that the Company will be able to do so. The value of the Common  Stock  issuable
upon conversion of the Preferred Shares may be greatly reduced if a registration
statement  covering  such  Common  Stock  is  not  kept  effective,  or if  such
securities  are not qualified,  or exempt from  qualification  under  applicable
state acts.

                                       7
<PAGE>
                                   Page - 35


No Dividends  Anticipated.  The Company has never paid any cash dividends on its
common  stock and does not  anticipate  the  payment  of cash  dividends  in the
foreseeable future.

Substantial  Influence of the Market Makers. There is a limited number of market
makers  which  currently  make a  market  in the  Company's  securities  and the
securities  are thinly  traded.  Consequently,  such  market  makers may exert a
dominating  influence  on the market  for such  securities.  Such  market-making
activity  may be  discontinued  at any  time.  The price  and  liquidity  of the
Company's securities may be significantly  affected by the degree of any current
market maker's participation in such market.

                                       8

<PAGE>
                                    Page - 1
                                                                   Exhibit 11.1
<TABLE>

                             SYMBOLLON CORPORATION

                 STATEMENT RE COMPUTATION OF PER SHARE EARNINGS


<CAPTION>
                                  The Three-Months Ended September 30,   The Nine-Months Ended September 30,
                                  ------------------------------------   -----------------------------------
                                         1996             1995                 1996              1995
                                     -----------      -----------           -----------      -----------
<S>                                  <C>              <C>                   <C>              <C>
Net Loss..........................   $  (245,476)     $  (319,672)          $  (718,185)     $(1,083,507)

Primary loss per share (1):
  Weighted average common shares
  outstanding.....................     2,715,296        2,457,047             2,559,095        2,419,225




  Shares subject to restriction...      (700,000)        (700,000)             (700,000)        (700,000)
                                     -----------      -----------           -----------       ----------
                                       2,015,296        1,757,047             1,859,095        1,719,225
                                     ===========      ===========           ===========       ==========

Loss per share (2):...............   $     (0.12)     $     (0.18)          $     (0.39)      $    (0.63)
                                     ===========      ===========           ===========       ==========

(1) The shares for the  three-month  and nine-month  periods ended September 30,
1996 and 1995 have been  calculated in  accordance  with  Accounting  Principles
Board Opinion No. 15.

(2) There is no difference  between  primary and fully diluted income (loss) per
share.

</TABLE>


<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
CONDENSED UNAUDITED FINANCIAL STATEMENT OF SYMBOLLON CORPORATION FOR THE NINE
MONTHS ENDED SEPTEMBER 30, 1996 AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE
TO SUCH FINANCIAL STATEMENT AS FILED IN THE FORM 10-QSB. 
</LEGEND>
<MULTIPLIER>                                  1
       
<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                              DEC-31-1996
<PERIOD-START>                                 JAN-01-1996
<PERIOD-END>                                   SEP-30-1996
<CASH>                                         1,908,683
<SECURITIES>                                           0
<RECEIVABLES>                                     23,414
<ALLOWANCES>                                           0
<INVENTORY>                                       30,415
<CURRENT-ASSETS>                               1,992,858
<PP&E>                                           254,404
<DEPRECIATION>                                   119,843
<TOTAL-ASSETS>                                 2,255,587
<CURRENT-LIABILITIES>                            141,916
<BONDS>                                                0
                                  0
                                          444
<COMMON>                                           2,483
<OTHER-SE>                                     2,092,994
<TOTAL-LIABILITY-AND-EQUITY>                   2,255,587
<SALES>                                           50,241
<TOTAL-REVENUES>                                 684,357
<CGS>                                             36,179
<TOTAL-COSTS>                                     36,179
<OTHER-EXPENSES>                                 872,752
<LOSS-PROVISION>                                       0
<INTEREST-EXPENSE>                                 2,070
<INCOME-PRETAX>                                 (718,185)
<INCOME-TAX>                                           0
<INCOME-CONTINUING>                             (718,185)
<DISCONTINUED>                                         0
<EXTRAORDINARY>                                        0
<CHANGES>                                              0  
<NET-INCOME>                                    (718,185)
<EPS-PRIMARY>                                       (.39)
<EPS-DILUTED>                                       (.39)
        


</TABLE>


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