SYMBOLLON CORP
8-K, 1998-05-27
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549




                                    Form 8-K

                                 CURRENT REPORT

                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

                Date of Report (Date of earliest event reported):
                                  May 20, 1998



                             SYMBOLLON CORPORATION
             (Exact name of Registrant as specified in its charter)


    Delaware                   0-22872                       36-3463683
(State or other         (Commission File Number)          (I.R.S. Employer
jurisdiction of                                           Identification No.)
incorporation)


                37 Loring Drive, Framingham, Massachusetts 01702
               (Address of principal executive offices) (Zip Code)

               Registrant's telephone number, including area code:

                                 (508) 620-7676


<PAGE>


Item 4.  Changes in Registrant's Certifying Accountant

                  Effective  April 1,  1998,  the  Boston  office of  Richard A.
Eisner & Company,  LLP ("RAE") was merged into the Boston office of BDO Seidman,
LLP  ("BDO").  This  merger  resulted  in RAE no longer  having an office in the
Boston area, and Symbollon  Corporation (the "Company")  concluded that it would
be  appropriate  to select a new  accounting  firm. At a meeting of the Board of
Directors of the Company on May 20, 1998, it was voted to retain BDO to serve as
the Company's independent auditors,  effective immediately.  RAE's report on the
Company's financial statements for the past two years did not contain an adverse
opinion or disclaimer of opinion, and was not modified as to uncertainty,  audit
scope or  accounting  principles.  During the  Company's  two most recent fiscal
years or any subsequent interim period, there were no disagreements  between the
Company and RAE on any matter of accounting  principles or practices,  financial
statement  disclosure,  or auditing scope or procedure which, if not resolved to
the  satisfaction  of RAE, would have caused it to make reference to the subject
matter  of the  disagreement  in  connection  with  its  report  on the  audited
financial statements.

Item 7.  Financial Statements, Pro Forma Financial Information and Exhibits

         (c)  Exhibits.

         16.1    The letter of RAE, dated May 26, 1998, stating that it agrees
                 with the statements made by the Company herein is attached
                 hereto.
  
<PAGE>


                                    SIGNATURE



                  Pursuant to the requirements of the Securities Exchange Act of
1934,  the  Registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.

May 27, 1998


                                         SYMBOLLON CORPORATION



                                         By: /s/ Paul C. Desjourdy
                                            ----------------------
                                            Paul C. Desjourdy
                                            Executive Vice President and
                                            Chief Financial Officer


<PAGE>

                               INDEX TO EXHIBITS

Exhibits                    Description                              Page No.
- - --------                    -----------                              --------

16.1               Letter of Richard A. Eisner & Company, LLP,
                   dated May 26, 1998.




May 26, 1998

Securities and Exchange Commission
450 Fifth Street, NW
Washington, DC 20549

Re: Symbollon Corporation Commission File # 0-22872


We were previously the independent auditors for Symbollon Corporation (the
"Company").  We were informed by facsimile on May 21, 1998 that our engagement
as principal auditor was terminated.  We have read the statements included
under Item 4 of Form 8-K dated May 20, 1998, of the Company and except for the
references to the retention of BDO Seidman, LLP in paragraph of Item 4, as to
which we have no knowledge, we agree with the statements in such Item.

Very truly yours,

/S/ Richard A. Eisner & Company, LLP

Richard A. Eisner & Company, LLP



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