SYMBOLLON CORP
10QSB, 1999-08-13
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                    U.S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                  Form 10-QSB

(Mark One)
|X|      QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
         ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED JUNE 30, 1999
| |      TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES
         EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM ______ TO ________

Commission file number  0-22872
                       ---------

                              SYMBOLLON CORPORATION
- -------------------------------------------------------------------------------
       (Exact name of small business issuer as specified in its charter)

            Delaware                            36-3463683
- -------------------------------            ------------------------
(State or other jurisdiction of              (I.R.S. Employer
incorporation or organization)              Identification No.)

                    37 Loring Drive, Framingham, MA 01702
- -------------------------------------------------------------------------------
                    (Address of principal executive offices)

                                  508-620-7676
- -------------------------------------------------------------------------------
                (Issuer's telephone number, including area code)


- -------------------------------------------------------------------------------
        (Former name, former address and former fiscal year, if changed
                               since last report)

Check  whether the issuer (1) filed all reports  required to be filed by Section
13 or 15(d) of the  Exchange  Act during the past 12 months (or for such shorter
period that the registrant was required to file such reports),  and (2) has been
subject to such filing requirements for the past 90 days. Yes X No

State the number of shares outstanding of each of the issuer's classes of common
equity, as of the latest practicable date.

                                     August 13, 1999
                                    -----------------
        Class A Common Stock            3,786,048
        Class B Common Stock               15,738

Transitional Small Business Disclosure Format (check one):

                    Yes             No    X
                        --------       --------

<PAGE>

                              SYMBOLLON CORPORATION
                          (a development stage company)

                                      INDEX

                                                                          PAGE
PART I.  FINANCIAL INFORMATION

         Item 1.  Financial Statements

                  Unaudited Condensed Balance Sheets
                      - June 30, 1999 and December 31, 1998                 1

                  Unaudited Condensed Statements of Operations
                      and Deficit Accumulated During the Development
                      Stage - For the six and three months
                      ended June 30, 1999 and June 30, 1998                 2

                  Unaudited Condensed  Statements  of  Cash  Flows
                      - For the six months ended June 30, 1999
                      and June 30, 1998                                     3

                  Notes to the Unaudited Condensed Financial Statements     4

         Item 2.  Management's Discussion and Analysis
                           or Plan of Operation                             5

PART II.  OTHER INFORMATION

         Item 2. Changes in Securities and Use of Proceeds                  8

         Item 4. Submission of Matters to a Vote of Security Holders        9

         Item 5. Other Information                                         10

         Item 6.  Exhibits and Reports on Form 8-K                         11

SIGNATURE                                                                  11

INDEX TO EXHIBITS                                                          12


<PAGE>

                        Part I - Financial Information

Item 1 - Financial Statements
<TABLE>

                             SYMBOLLON CORPORATION
                         (a development stage company)

                            CONDENSED BALANCE SHEETS
                                   (Unaudited)

                                     ASSETS
<CAPTION>
                                                                            June 30,       December 31,
                                                                              1999              1998
                                                                          -------------     ------------
Current assets:
<S>                                                                        <C>               <C>
  Cash and cash equivalents............................................... $ 1,202,538      $ 1,514,115
  Restricted cash.........................................................     301,550          297,554
  Accounts receivable.....................................................      76,248          207,172
  Inventory...............................................................      81,161           69,382
  Prepaid expenses........................................................      27,479           83,104
                                                                           -----------      -----------
        Total current assets.............................................. $ 1,688,976      $ 2,171,327

Equipment and leasehold improvements, net of
 accumulated depreciation and amortization................................     108,990          125,572
Other assets:
    Patent and trademark cost, net of accumulated amortization............     213,455          205,226
    Deposit...............................................................       2,364            2,364
                                                                          ------------      -----------
        TOTAL............................................................. $ 2,013,785      $ 2,504,489
                                                                          ============      ===========

                                   LIABILITIES
Current liabilities:
  Accounts payable........................................................ $   134,467      $    87,654
  Accrued expenses........................................................     340,770            4,403
  Other current liabilities...............................................       1,450           19,149
                                                                          ------------      -----------
        Total current liabilities.........................................     476,687          111,206

Redeemable common stock, Class A, par value $.001 per share,
 186,667 and 669,545 shares issued at June 30, 1999
 and December 31, 1998, respectively (aggregate involuntary
 liquidation value $350,000 and $850,000, respectively)...................     350,000          850,000

                               STOCKHOLDERS' EQUITY

Preferred  stock,  par  value  $.001  per  share,  5,000,000  shares
 authorized, none issued..................................................
Common stock, Class A, par value $.001 per share,
 18,750,000 shares authorized, 3,404,164 and 2,919,786 shares issued at
 June 30, 1999 and December 31, 1998, respectively........................       3,404            2,920
Convertible Common stock, Class B, par value $.001 per share,
 1,250,000 shares authorized, 15,738 shares issued at
 June 30, 1999 and December 31, 1998, respectively........................          16               16
Additional paid-in capital................................................   7,756,478        7,254,712
Deficit accumulated during the development stage..........................  (6,572,800)      (5,714,365)
                                                                          ------------      -----------
     Total stockholders' equity...........................................   1,187,098        1,543,283
                                                                          ------------      -----------

        TOTAL............................................................. $ 2,013,785      $ 2,504,489
                                                                          ============      ===========
</TABLE>

See notes to condensed financial statements.

                                        1




<PAGE>


<TABLE>

                             SYMBOLLON CORPORATION
                          (a development stage company)

           CONDENSED STATEMENTS OF OPERATIONS AND DEFICIT ACCUMULATED
                          DURING THE DEVELOPMENT STAGE
                                  (Unaudited)
<CAPTION>
                                                                                                               Period From
                                                                                                              July 15, 1986
                                                        Three Months Ended            Six Months Ended       (Inception) to
                                                              June 30,                    June 30,              June 30,
                                                         1999         1998           1999          1998           1999
                                                     -----------   -----------    -----------   -----------    -----------
<S>                                                  <C>           <C>            <C>           <C>            <C>
Revenue:
Net product sales.................................   $             $   110,501    $   172,500   $   110,501    $ 1,213,488
Contract revenue..................................       105,886                      188,879                      833,629
License fee revenue...............................                                                               2,190,000
                                                     -----------   -----------    -----------   -----------    -----------
        Total revenue.............................       105,886       110,501        361,379       110,501      4,237,117

Operating Expenses:
    Cost of goods sold............................   $    27,182   $    73,208    $   140,190   $    73,208    $   735,391
    Research and development costs................       474,003       281,508        914,108       533,895      6,195,822
    General and administrative expenses...........        95,725       106,596        196,019       265,249      4,131,285
                                                     -----------   -----------    -----------   -----------    -----------
        Total operating expenses..................       596,910       461,312      1,250,317       872,352     11,062,498
                                                     -----------   -----------    -----------   -----------    -----------

Income (Loss) from operations.....................      (491,024)     (350,811)      (888,938)     (761,851)    (6,825,381)

Interest income...................................        13,373        24,874         30,503        55,076        608,841

Interest expense and debt issuance costs..........                                                                (356,260)
                                                     -----------   -----------    -----------   -----------    -----------

Net Income (Loss).................................   $  (477,651)  $  (325,937)   $  (858,435)  $  (706,775)   $(6,572,800)
                                                                                                               ===========
Basic Net Income (Loss) per share of common stock.   $     (0.16)  $     (0.13)   $     (0.30)  $     (0.28)
                                                     ===========   ===========    ===========   ===========

Diluted Net Income (Loss) per share of common stock  $     (0.16)  $     (0.13)   $     (0.30)  $     (0.28)
                                                     ===========   ===========    ===========   ===========

Weighted average number of common shares
 outstanding......................................     2,905,069     2,498,691      2,905,069     2,498,691
                                                     ===========   ===========    ===========   ===========

Weighted average number of common shares and
 potential dilutive common shares outstanding.....     2,905,069     2,498,691      2,905,069     2,498,691
                                                     ===========   ===========    ===========   ===========


</TABLE>

See notes to condensed financial statements.

                                       2

<PAGE>


<TABLE>
                             SYMBOLLON CORPORATION
                         (a development stage company)

                       CONDENSED STATEMENTS OF CASH FLOWS
                                  (Unaudited)
<CAPTION>
                                                                                           Period From
                                                                                          July 15, 1986
                                                                 Six Months Ended        (Inception) to
                                                                     June 30,               June 30,
                                                                1999          1998           1999
                                                             -----------   -----------    -----------
<S>                                                          <C>           <C>            <C>
Cash flows from operating activities:
    Net income (loss).....................................   $  (858,435)  $  (706,775)   $(6,572,800)
    Adjustments  to  reconcile  net income (loss) to net
    cash  provided  by  (used  in) operating activities:
      Depreciation and amortization expense...............        22,892        23,533        451,271
      Amortization of debt issuance costs.................                                    130,000
      Accrued rent........................................
      Loss on disposition of equipment....................                                     19,542
      Changes in:
        Restricted cash...................................        (3,996)                    (301,550)
        Accounts receivable...............................       130,924       (21,953)       (76,248)
        Inventory.........................................       (11,779)       16,611        (81,161)
        Prepaid expenses..................................        55,625        44,350        (27,479)
        Accounts payable and other current liabilities....       365,481        49,980        533,862
                                                             -----------   -----------    -----------
        Net cash provided by (used in)
        operating activities..............................      (299,288)     (594,254)    (5,924,563)
                                                             -----------   -----------    -----------
Cash flows from investing activities:
    Equipment and leasehold improvements costs............        (2,964)      (24,173)      (367,790)
    Patent and trademark costs............................       (11,575)      (35,866)      (436,768)
    Proceeds from sale of equipment.......................                                     11,300
    Deposit...............................................                                     (2,364)
                                                             -----------   -----------    -----------
      Net cash provided by (used in) investing activities.       (14,539)      (60,039)      (795,622)
                                                             -----------   -----------    -----------
Cash flows from financing activities:
    Warrant conversion....................................                                    629,204
    Borrowings from stockholders..........................                                    253,623
    Repayment to stockholders.............................                                   (127,683)
    Sale of common stock and units........................         2,250         1,312      8,060,981
    Sale of option to purchase units......................                                        100
    Public offering costs.................................                                 (1,343,502)
    Issuance of preferred stock...........................                                    450,000
                                                             -----------   -----------    -----------
      Net cash provided by financing activities...........         2,250         1,312      7,922,723
                                                             -----------   -----------    -----------
NET INCREASE (DECREASE) IN CASH...........................      (311,577)     (652,981)     1,202,538
Cash at beginning of period...............................     1,514,115     2,527,865
                                                             -----------   -----------    -----------
CASH AT END OF PERIOD.....................................   $ 1,202,538   $ 1,874,884    $ 1,202,538
                                                             ===========   ===========    ===========
</TABLE>

See notes to condensed financial statements.

                                      3

<PAGE>

                              SYMBOLLON CORPORATION
                          (a development stage company)

                     NOTES TO CONDENSED FINANCIAL STATEMENTS
                                   (Unaudited)

Note A - Description of Business:

         Symbollon  Corporation  ("Symbollon"  or the  "Company")  was formed to
develop  and  commercialize  proprietary  iodine-based  products  for  infection
control and treatment in biomedical and bioagricultural  industries. The Company
is  in  the  development  stage  and  its  efforts  since  inception  have  been
principally  devoted to research and development,  securing patent and trademark
protection  and raising  capital.  Management  of the Company  anticipates  that
additional  losses will be incurred as these efforts are pursued.  In 1995,  the
Company  signed a  marketing  and supply  agreement  for its first  product  and
commenced shipping.

Note B - Accounting Policies and Disclosure:

         The accompanying  unaudited financial  statements do not contain all of
the disclosures required by generally accepted accounting  principles and should
be read in conjunction with the financial  statements and related notes included
in the Company's Form 10-KSB for the year ended December 31, 1998 filed with the
Securities and Exchange Commission.

         In the opinion of  management,  the  financial  statements  reflect all
adjustments,  all of which are of a normal recurring  nature,  to fairly present
the Company's  financial  position,  results of operations  and cash flows.  The
results of operations  for the six and  three-month  periods ended June 30, 1999
are not necessarily indicative of the results to be expected for the full year.

Note C - Capitalization:

         Pursuant to stockholder  approval  received on May 26, 1999 at the 1999
Annual Meeting,  the Company is offering (the "Offering") in a private placement
up to 1,250,00 units (the "Units"), each Unit consisting of one share of Class A
Common Stock and one redeemable  warrant. As of August 13, 1999, the Company has
sold in the third quarter  288,550  Units for  $504,962.50  ($457,747.50  net of
underwriter's  commissions).  Under the Offering,  the Company may sell up to an
additional 961,450 Units (see Part II - Item 2.
"Changes in Securities and Use of Proceeds" below).

         On August 4, 1999,  the Company was required to redeem 93,333 shares of
Class A Common Stock held by Bausch & Lomb Pharmaceuticals,  Inc. in conjunction
with the  satisfaction  of a  milestone  payment  under  its  collaboration  and
sale/license  agreement with Bausch & Lomb. The shares were redeemed at Bausch &
Lomb's original purchase price of $1.875 per share.


<PAGE>


Item 2.  Management's Discussion and Analysis or Plan of Operation

MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS

         Symbollon  Corporation  ("Symbollon" or the "Company") is a development
stage  company.  Since  inception  of the  Company's  predecessor  in 1986,  the
Company's  efforts have been  principally  devoted to research and  development,
securing  patent and trademark  protection  and raising  capital,  most of which
efforts  commenced after May 1991. Except for revenue earned since 1995 on sales
of  IodoZyme,  the  Company's  sole  revenue to date has been from  research and
development contracts with corporate partners and interest income.

Forward-Looking Statements

         In  addition  to the  historical  information  contained  herein,  this
Quarterly Report on Form 10-QSB contains "forward-looking statements" within the
meaning of the Private Securities Litigation Reform Act of 1995, including,  but
not limited to  statements  concerning  plans,  objectives,  goals,  strategies,
prospects,  financial needs, future performance, costs and expenditures and Year
2000  matters.   Such  statements  may  be  identified  or  qualified,   without
limitation,  by words such as  "likely",  "will",  "suggests",  "may",  "would",
"could", "should", "expects",  "anticipates",  "estimates", "plans", "projects",
"believes",  or similar expressions (and variants of such words or expressions).
Investors  are  cautioned   that   forward-looking   statements  are  inherently
uncertain.  Actual  performance,  achievements and results may differ materially
from those expressed,  projected or suggested in the forward-looking  statements
due to certain  risks and  uncertainties,  including,  but not  limited  to, the
Company's  early stage of  development,  dependence on  collaborative  partners,
additional financing requirements and availability, history (and expectation) of
losses,   uncertainty  of  patent   protection,   uncertainty   associated  with
preclinical  and  clinical  testing,  market  acceptance,  intense  competition,
government  regulation,  dependence  on key  personnel,  lack of  marketing  and
manufacturing experience,  reimbursement and drug pricing uncertainty, potential
product  liability,  material  incompatibility,  ability to maintain  its Nasdaq
SmallCap Market listing,  possible Year 2000 problems,  hazardous materials, and
the other risks and  uncertainties  described or discussed in the section  "Risk
Factors" in the Annual  Report on Form 10-KSB for the period ended  December 31,
1998. The  forward-looking  statements  contained herein represent the Company's
judgment as of the date of the Quarterly Report on Form 10-QSB,  and the Company
cautions readers not to place undue reliance on such statements.

Results of Operations

         Symbollon's net loss for the three-month period ended June 30, 1999 was
$477,651,  reflecting  an  increase  of  $151,714  or  46.5%  from a net loss of
$325,937 in the comparable  1998 period.  Symbollon's net loss for the six-month
period ended June 30, 1999 was  $858,435,  reflecting an increase of $151,660 or
21.5% from a net loss of $706,775 in the comparable  1998 period.  The increased
loss for the three-month  period resulted  primarily from increased  development
expenses related to the Company's ongoing Phase II clinical trial. The increased
loss for the six-month  period  resulted  primarily from  increased  development

<PAGE>

expenses  related to the Company's  ongoing Phase II clinical  trial,  partially
offset by increased  contract  revenues  from  corporate  partners and decreased
general and  administrative  expenses.  The Company expects to continue to incur
operating losses for the foreseeable future.

         Product  revenues  from sales of IodoZyme  for the three and  six-month
periods ended June 30, 1999 were none and $172,500,  compared to $110,501 in the
comparable  1998 periods.  Because the  Company's  exclusive  marketing  partner
orders IodoZyme a limited number of times each year, the changes between periods
reflect mostly timing  differences in receipt of those orders from the marketing
partner,  and the increased  sales for the six-month  period do not  necessarily
reflect correspondingly increased sales for the entire year.

         The gross profit margin on product sales for the six-month period ended
June 30,  1999 were 19%,  compared to 34% in the  comparable  1998  period.  The
decrease  in the gross  profit  margin on  product  sales was  primarily  due to
increased labor and component cost and overhead expenses.

         Contract  revenues for the three and  six-month  periods ended June 30,
1999  were  $105,886  and  $188,879,  compared  to none in the  comparable  1998
periods.  The contract  revenues for the three and six-month  periods ended June
30, 1999 were generated  from  development  activities  related to the corporate
relationship with Bausch & Lomb Pharmaceuticals, Inc.

         Research and development  expenses for the three and six-month  periods
ended  June 30,  1999  were  $474,003  and  $914,108,  respectively,  reflecting
increases of $192,495  and  $380,213,  respectively,  from the  comparable  1998
periods.  The increases resulted from increased  development expenses related to
the Company's drug candidate for the treatment of  fibrocystic  breast  disease,
including  consulting  fees and clinical  costs  associated  with the  Company's
ongoing Phase II clinical  trial and  conducting a Phase I clinical  trial.  The
Company anticipates that research and development expenses will remain high over
the  remainder of 1999 as the Company  completes  its ongoing  Phase II clinical
trial for its drug to treat fibrocystic breast disease.

         General and administrative expenses for the three and six-month periods
ended  June  30,  1999  were  $95,725  and  $196,019,  respectively,  reflecting
decreases  of  $10,871  and  $69,230,  respectively,  from the  comparable  1998
periods.  The decreases  resulted primarily from decreased employee salaries and
related costs and investor and public relations expenses.

Liquidity and Capital Resources

         The Company has funded its activities through proceeds from private and
public  placements  of equity  and debt  securities.  As of June 30,  1999,  the
Company had working capital of $1,212,289.

         The Company  continues  to incur  operating  losses and has  incurred a
cumulative  loss  through  June 30,  1999 of  $6,572,800.  However,  the Company
believes that it has the necessary  liquidity  and capital  resources,  together
with anticipated  future revenues,  to sustain planned operations for the twelve
months  following  June 30,  1999.  In the  event  that the  Company's  internal

<PAGE>

estimates  relating to its planned  revenues or  expenditures  prove  materially
inaccurate,  the Company may be required to  reallocate  funds among its planned
activities and curtail certain planned  expenditures.  In any event, the Company
anticipates  that it will  require  additional  funds after June 30,  2000,  and
therefore,  the  Company  will  continue to seek new  financing  during the next
twelve months.

         The Company's ability to obtain new financing may, in part, be affected
by the Company's  ability to maintain its listing on the Nasdaq SmallCap Market.
Nasdaq's current SmallCap continued listing criteria require,  in part, that the
Company  maintain net tangible  assets (as defined by Nasdaq,  total assets less
total liabilities and goodwill) of at least  $2,000,000,  a minimum bid price of
$1.00 per share of common stock and two market  makers for its  securities.  The
Company has received  notification  from Nasdaq that the Company  failed to meet
the continued  listing  requirements  because its net tangible assets were below
$2,000,000  as of December 31, 1998,  and remain below as of June 30, 1999.  The
Company's  qualification  hearing with Nasdaq was held on August 12,  1999.  The
Company  requested a temporary  waiver from the continued  listing  requirements
while the Company attempts to complete its planned  financing.  If such a waiver
is not  granted,  or if granted,  the  Company is not able to obtain  sufficient
equity financing,  then the Company's Class A Common Stock will be delisted from
the Nasdaq  SmallCap  Market.  There can be no assurance  that Nasdaq will grant
such  waiver,  or if such  waiver is granted,  that the Company  will be able to
obtain sufficient equity financing to maintain such Nasdaq listing.

         During  the  remainder  of  1999,   the  Company   anticipates   paying
approximately  $152,500 as compensation for its current executive officers,  and
approximately  $15,300  for  lease  payments  on  its  facilities.  The  Company
anticipates  that the Phase II clinical trial for its drug to treat  fibrocystic
breast disease will cost  approximately  $450,000 over the remainder of 1999. At
December 31, 1998, the Company had a net operating loss carryforward for Federal
income tax purposes of approximately $5,452,000 expiring through 2018.

         The Year 2000 ("Y2K") issue is the result of computer  programs using a
two-digit format, as opposed to four digits, to indicate the year. Such computer
systems  will be unable to  interpret  dates  beyond the year 1999,  which could
cause a system  failure or other  computer  errors,  leading to  disruptions  in
operations.  The Company has  identified  three  major  areas  determined  to be
critical for successful Y2K  compliance:  (1) financial and  information  system
applications,  (2) manufacturing applications and (3) third-party relationships.
In the financial and information  system and manufacturing  areas, the Company's
core financial and reporting  systems,  which were not Y2K compliant,  have been
replaced with Y2K compliant systems.  The Company is requesting  assurances from
all software  vendors from which it has  purchased or from which it may purchase
software that such software will correctly  process all date  information at all
times.  In the  third-party  area,  the Company is in the process of identifying
areas of exposure.  The Company is querying its suppliers and  contractors as to
their  progress in  identifying  and  addressing  problems  that their  computer
systems  will face in correctly  processing  date  information  as the Year 2000
approaches.  The Company has not determined what costs, if any, will be incurred
in connection with the  third-party  area. The failure by the Company or a third
party  supplier or  contractor to correct a material Y2K problem could result in
an  interruption  in, or failure  of,  certain  normal  business  activities  or
operations.  Such failures could  materially and adversely  affect the Company's
results of  operations,  liquidity and financial  condition.  Due to the general

<PAGE>

uncertainty inherent in the Y2K problem,  resulting in part from the uncertainty
of  the  Y2K  readiness  of  the  Company's  customers,   suppliers,  and  other
third-party  providers,  the Company is unable to determine at this time whether
the  consequences  of any  Y2K  failures  will  have a  material  impact  on the
Company's results of operations, liquidity or financial condition.


 Part II - Other Information

Item 2.  Changes in Securities and Use of Proceeds

         A.  On  May  26,  1999,  at  the  1999  Annual  Meeting  the  Company's
stockholders  approved  certain  amendments  to  the  Company's  Certificate  of
Incorporation  to:  (a)  classify  the  Board,  effective  with the 1999  Annual
Meeting,  into  three  classes,  as  nearly as equal as  possible,  so that each
director  (after a  transitional  period) will serve for three  years,  with one
class of directors  being elected each year;  (b) provide that  directors may be
removed only for cause by the affirmative  vote of at least eighty percent (80%)
of the voting  power of all of the  outstanding  shares of capital  stock of the
Company entitled to vote generally in the election of directors, voting together
as a single class;  (c) provide that any vacancy on the Board may be filled only
by a majority vote of the directors then in office,  even if less than a quorum,
and that a  director  elected  to fill a  vacancy  hold  office  until  the next
election  of the class for which  such  director  shall  have been  chosen;  (d)
increase the  stockholder  vote  required to alter,  amend,  repeal or adopt any
provision inconsistent with these proposed amendments to at least eighty percent
(80%) of the voting power of all of the  outstanding  shares of capital stock of
the Company  entitled to vote  generally in the elections of  directors,  voting
together as a single class;  and (e) provide for certain other related  matters.
The full text of the proposed amendments to the Certificate of Incorporation are
set forth in Exhibit A to this Proxy Statement,  and the descriptions thereof in
this Proxy Statement are qualified in their entirety by reference  thereto.  The
Company's Amended Certificate of Incorporation is filed herewith as Exhibit 3.1.

         B.       Not applicable.

         C.(i). Pursuant to stockholder approval received on May 26, 1999 at the
1999  Annual  Meeting,  the Company is offering  (the  "Offering")  in a private
placement for sale to persons who qualify as "accredited investors" as that term
is defined in Rule 501 promulgated  under the Securities Act of 1933, as amended
(the "Securities Act"),  units (the "Units"),  each Unit consisting of one share
of Class A Common  Stock and one  redeemable  warrant (the  "Warrants"),  with a
minimum offering of 100,000 Units and a maximum offering of 1,250,000 Units (the
"Maximum  Offering").  Each Warrant will be exercisable for a four-year  period,
beginning on the date of the initial  closing of the  Offering,  to purchase one
share of Class A Common  Stock at exercise  prices per share of $3.00 during the
first year,  $4.00 during the second year, $5.00 during the third year and $6.00
thereafter.  It is currently anticipated that the Warrants will be redeemable at
the option of Company at $0.01 per Warrant in the event that the average closing
bid price as quoted by Nasdaq (the  average  last  reported  sales price if then
listed on any  national  securities  exchange)  of the Class A Common Stock over
twenty  successive  trading  days is equal to or greater  than $5.00  during the
first year,  $6.00 during the second year, $7.00 during the third year and $8.00
thereafter,  subject to the holder's  right to  exercise.  If the Class A Common

<PAGE>

Stock is  neither  quoted  on the  Nasdaq  Market  nor  listed  on any  national
securities  exchange,  it is anticipated that the Warrants will be redeemable at
the option of the Company if the average  closing bid price of the Common  Stock
as reported in the over-the-counter market in the so-called "pink sheets" or the
"OTC Bulletin Board Service" over twenty successive trading days is $1.00 higher
than the price for each  relevant  redemption  period set forth in the preceding
sentence.

         The Company has  retained  Indianapolis  Securities,  Inc.,  a National
Association  of  Securities  Dealers  (NASD)  member,  as  placement  agent (the
"Placement  Agent")  in  connection  with the  Offering  of the Units on a "best
efforts" basis.  The Company has agreed to pay the Placement Agent a ten percent
(10.0%)  cash  commission  and  Warrants  equal to 10.0% of the Units  sold (the
"Placement Agent Warrants") for investors identified and brought to the Offering
by the Placement Agent. For investors  identified and brought to the Offering by
the  Company,  the  Placement  Agent will not  receive any cash  commissions  or
Placement Agent Warrant allocations.

         The Units will be offered in  accordance  with Rule 506 of Regulation D
promulgated under the Securities Act, and accordingly the securities  offered in
the Offering  will not be  registered  under the  Securities  Act and may not be
offered or sold by the holders  thereof  absent  registration  or an  applicable
exemption  from  the  registration  requirements.  The  Company  will,  however,
undertake to use its commercially reasonable best efforts to file a registration
statement  under the  Securities  Act to  register  for resale the shares of the
Class A Common  Stock  included in the Units and issuable  upon  exercise of the
Warrants  no later  than  eight (8) months  following  the final  closing of the
Offering.

         As of August  13,  1999,  the  Company  has sold in the  third  quarter
288,550 Units for $504,962.50  ($457,747.50 net of  underwriter's  commissions).
Under the Offering, the Company may sell up to an additional 961,450 Units.

         C.(ii).  On August 4, 1999,  the Company was required to redeem  93,333
shares of Class A Common  Stock held by Bausch & Lomb  Pharmaceuticals,  Inc. in
conjunction with the satisfaction of milestone  payment under its  collaboration
and  sale/license  agreement  with Bausch & Lomb.  The shares  were  redeemed at
Bausch & Lomb's original purchase price of $1.875 per share.

Item 4.  Submission of Matters to a Vote of Security Holders

         The following items were submitted to a vote of the stockholders at the
Company's Annual Meeting on May 26, 1999:



<PAGE>


         1.       Election of Directors.  The following directors were elected:

                                                           Votes
                                               For        Against  Withheld

                  James C. Richards         3,340,241      32,022     0
                  Jack H. Kessler           3,340,241      32,022     0
                  Paul C. Desjourdy         3,340,241      32,022     0
                  Richard F. Maradie        3,340,241      32,022     0
                  Eugene Lieberstein        3,340,241      32,022     0

         2. Amendment to the Company's 1993 Stock Option Plan.

                                                     Votes
                                    For              Against  Withheld
                                    2,457,550        95,322     12,900

         3. Amendment to the Company's Certificate of Incorporation.

                                                     Votes
                                    For              Against  Withheld
                                    2,457,550        95,322     12,900

         4. Proposal to issue and sell 1,250,000 Units in a private placement.

                                                     Votes
                                    For              Against  Withheld
                                    2,478,488        79,784      7,500

         5. Ratification of BDO Seidman,  LLP as the independent auditors of the
Company:

                                                     Votes
                                    For              Against  Withheld
                                    3,348,341        18,922      5,000

         Each  item  identified  above  was  described  in the  Company's  Proxy
Statement  for the  Annual  Meeting  of  Stockholders.  Each item  received  the
necessary votes for approval.

Item 5. Other Information

         1. In July 1999,  the  Company  received a notice of  termination  from
Watson  Pharmaceuticals,  Inc. regarding the Company's  collaborative  agreement
with Oclassen  Pharmaceuticals,  Inc.  covering the field of  dermatology.  Upon
receipt of the notice,  Symbollon is free to pursue the commercialization of the
Company's technology in the field of dermatology independent of Oclassen.


<PAGE>

         2. On August 4,  1999,  pursuant  to the  Company's  collaboration  and
sale/license  agreement  with  Bausch & Lomb  Pharmaceuticals,  Inc.,  Symbollon
received a $750,000  milestone  payment.  As  allowed  under its Stock  Purchase
Agreement,  Bausch & Lomb satisfied  $175,000 of its obligation by requiring the
Company to redeem 93,333  shares of its  redeemable  Class A Common  Stock.  The
shares were redeemed at Bausch & Lomb's  original  purchase  price of $1.875 per
share.

Item 6. Exhibits and Reports on Form 8-K

         (a)      Exhibits

                  See Index to Exhibits on Page E-1.

         (b)      Reports on Form 8-K

                  No reports on Form 8-K were filed during the quarter for which
this report is filed.


                                   SIGNATURES

         In accordance with the requirements of the Exchange Act, the registrant
caused this report to be signed on its behalf of the undersigned, thereunto duly
authorized.

                                SYMBOLLON CORPORATION



Date:  August 13, 1999          By: /s/ Paul C. Desjourdy
                                    -------------------------------------------
                                    Paul C. Desjourdy, Exec. Vice President/CFO
                                    and authorized signatory


<PAGE>


                              SYMBOLLON CORPORATION

                                INDEX TO EXHIBITS

                                                                         Page #

3.1  Amended Certificate of Incorporation of the Company; including
     Certificate of Designation, Preferences and Rights of Series A
     Preferred Stock of the Company.

3.2  Amended By-Laws of the Company.

10.1 1993 Stock Option Plan of the Company, as amended.

27.1 Financial Data Schedule.







                                                                     Exhibit 3.1

                          CERTIFICATE OF INCORPORATION

                                       OF

                              SYMBOLLON CORPORATION

         FIRST:   The  name  of  the  corporation  is  SYMBOLLON  CORPORATION
(hereinafter  referred  to  as  the "Corporation").

         SECOND: The address of the Corporation's registered office in the State
of Delaware is 32 Loockerman Square, Suite L-100, City of Dover, County of Kent,
19901.  The name of the  registered  agent at such address is The  Prentice-Hall
Corporation System, Inc.

         THIRD:   The  purpose  of  the  Corporation  is to  engage  in  any
lawful act or activity for which corporations may be organized under the
Delaware General Corporation Law.

         FOURTH:  I. The  aggregate  number of shares  which  the  Corporation
shall  have  authority  to issue is Twenty Five  Million  (25,000,000)  shares,
consisting  of (i) Eighteen Million Seven Hundred Fifty Thousand (18,750,000)
shares of Class A Common Stock, par value $.001 per share ("Class A Common
Stock"), (ii) One Million Two Hundred Fifty Thousand (1,250,000) shares of Class
B Common Stock, par value $.001 per share ("Class B Common Stock"), and (iii)
Five Million (5,000,000) shares of Preferred  Stock, par value $.001 per share
("Preferred Stock").

                 II. Except as otherwise provided in this Article FOURTH, the
rights, preferences and limitations of Class A Common Stock and Class B Common
Stock shall be identical in all respects:

                 (a) The dividend rights of the holders of shares of Class A
Common Stock and Class B Common Stock shall be identical, except that no stock
dividends on the Class A Common Stock may be paid in Class B Common Stock and no
stock dividends on the Class B Common Stock may be paid in Class A Common Stock.
Whenever a stock dividend is paid, the holder of a share of any class of common
stock shall be paid in the same number of shares of common stock of the class of
such shares as are paid to the holder of a share of common stock of any other
class in shares of common stock of such other class.  Whenever a combination
or subdivision of the shares  of any class of common stock is made, the same
combination or subdivision shall be made with respect to the other classes of
common stock.

                 (b) Each share of Class A Common Stock shall entitle the holder
to one vote and each share of Class B Common


<PAGE>



 Stock shall entitle the holder to
five votes on all matters with respect to which holders of such classes of stock
are entitled to vote.

                 (c) (i) All  outstanding  shares of Class B Common  Stock shall
be convertible at all times, at the election of the holder thereof, into an
equal number of fully paid and nonassessable shares of Class A Common Stock by
delivery of written notice by the holder of such shares of Class B Common Stock
to the Corporation, or its transfer agent, of his  election  together  with  the
certificate(s)   representing  the  shares  to  be  converted.   Thereupon,  the
Corporation,  or its transfer  agent,  as the case may be, shall  exchange  such
certificate(s) for a certificate or certificates representing an equal number of
shares of Class A Common  Stock.  Shares of Class B Common Stock shall be deemed
to have been  converted  immediately  prior to the close of  business on the day
upon which the  Corporation,  or its transfer  agent,  receives  such shares for
conversion.  The person  entitled to receive the Class A Common  Stock  issuable
upon such  conversion  shall be treated for all purposes as the record holder of
such Class A Common Stock at such time.

                     (ii)  Except as provided in subparagraph (iii) below, upon
the sale, assignment, transfer, conveyance, or other disposition, whether
voluntary, by operation of law or otherwise (a "Transfer", which, for the
purpose hereof, shall not include a pledge) of shares of Class B Common Stock,
other than a transfer to another holder of Class B Common Stock or to a private
charitable foundation as to which a holder of Class B Common Stock is the sole
voting member,  the shares so transferred shall, by  virtue  of  such  Transfer,
automatically be converted into an equal number of fully paid and  nonassessable
shares of Class A Common Stock.

                    (iii)  Upon the death of any holder of Class B Common Stock,
the shares of Class B Common Stock so held as of the date of death of the
deceased stockholder shall be automatically converted into an equal number of
fully paid and nonassessable shares of Class A Common Stock unless and to the
extent that any of such shares are purchased by another holder of Class B Common
Stock on or prior to 90 days from the date that a legal representative is duly
appointed by a court of competent jurisdiction, or 120 days from such date if
within such 90 day period another holder of Class B Common Stock has exercised
any right to purchase shares of Class B Common Stock held by such legal
representative.  If there should be only one holder of Class B Common Stock,
effective immediately upon his death, the shares of Class B Common Stock so held
as of the date of death shall be automatically converted into an equal number of
fully paid and nonassessable shares of Class A Common Stock.


<PAGE>



                   (iv)   With respect to any shares of Class B Common Stock
converted into Class A Common Stock pursuant to paragraphs (i), (ii) and (iii)
above, until surrender as hereinafter provided, each outstanding certificate,
which prior to such conversion represented shares of Class B Common Stock, shall
be deemed for all purposes to evidence ownership of the number of shares of
Class A Common Stock into which the shares of Class B Common Stock shall have
been converted.  Upon surrender to the Corporation, or its transfer agent, for
cancellation of the certificate or certificates representing such shares, the
holder thereof shall be entitled to receive a certificate or certificates
representing the number of shares of Common Stock to which such holder is
entitled.

                   (v)    With  respect to any shares of Class B Common Stock
converted into Class A Common Stock pursuant to paragraphs (i), (ii) or (iii)
above, such converted shares of Class B Common Stock shall, from and after the
date of conversion, have the status of authorized and unissued shares of Class B
Common Stock and may be reissued as shares of Class B Common Stock.

                 III. The Board of Directors of the  Corporation is authorized,
subject to  limitations  prescribed  by law and the  provisions  of this Article
FOURTH,  to provide for, from time to time, in one or more series of any number,
the issuance of shares of Preferred Stock, and, by filing a certificate pursuant
to the General Corporation Law of the State of Delaware, to establish the number
of  shares  to be  included  in each  such  series  and to fix the  designation,
relative rights,  preferences,  qualifications  and limitations of the shares of
each such  series.  The  authority of the Board  Directors  with respect to each
series  shall  include,  but not be  limited  to,  determination  of each of the
following:

                   A. The number of shares constituting that series and the
distinctive designation of that series;

                   B. The dividend rate on the shares of the series, whether
dividends shall be cumulative and, if so, from which date or dates, and whether
they shall be payable in preference to, or in another relation to, the dividends
payable on any other class or classes or series of stock;

                   C. Whether that series shall have voting rights, in addition
to the voting rights provided by law, and, if so, the terms of such voting
rights;

                   D. Whether that series shall have conversion or exchange
privileges, and, if so, the terms and


<PAGE>



 conditions of such conversion or exchange,
including provision for  adjustment  of the  conversion or exchange rate in such
events as the Board of Directors shall determine;


                   E. Whether or not the shares of that series shall be
redeemable, and if so,  the terms and conditions of such redemption, including
the manner of selecting shares for redemption if less than all such shares are
to be redeemed, the date or dates upon or after which they shall be redeemable,
and the amount per share payable in case of redemption, which amount may vary
under different conditions and at different redemption dates;

                   F. Whether  that series shall be entitled to the benefit of a
sinking fund to be applied to the purchase or redemption of shares of that
series and, if so, the terms and amounts of such sinking fund;

                   G. The right of the shares of the  series to the  benefit  of
conditions and restrictions upon the creation of indebtedness of the Corporation
or any subsidiary,  upon the issue of any additional stock (including additional
shares of such series or of any other  series) and upon the payment of dividends
or the making  of  other  distributions  on  and  the  purchase,  redemption  or
other acquisition by the Corporation or any subsidiary of, any outstanding stock
of the Corporation;

                   H. The right of the shares of that series in the event of any
voluntary or involuntary liquidation, dissolution or winding up of the
Corporation, and whether  such rights  shall be in  preference  to or in another
relation to the comparable rights of any other class or classes or series of
stock; and

                   I. Any other relative, participating optional or other
special,  rights, qualifications, limitations or restrictions of that series.

                 IV.  Shares of any series of  Preferred  Stock which have been
redeemed  (whether  through the  operation  of a sinking fund or  otherwise)  or
which, if convertible or exchangeable, have been converted into or exchanged for
shares  of stock of any  other  class  or  classes,  shall  have the  status  of
authorized and unissued  shares of Preferred Stock of the same series and may be
reissued  as part of the series of which they were  originally  a part or may be
reclassified and reissued as part of any other series of Preferred Stock or of a
new series of Preferred  Stock to be created by resolution or resolutions of the
Board of  Directors,  all  subject to the  conditions  and the  restrictions  on


<PAGE>



issuance  set forth in the  resolution  or  resolutions  adopted by the Board of
Directors providing for the issue of any series of Preferred Stock.

                  V.  Except  as  otherwise   provided  by  the   resolution  or
resolutions  providing  for the issue of any series of  Preferred  Stock,  after
payment  shall  have been made to the  holders  of  Preferred  Stock of the full
amount of dividends to which they shall be entitled  pursuant to the  resolution
or resolutions  providing for the issuance of any series of preferred Stock, the
holders of Class A and Class B Common Stock shall be entitled,  to the exclusion
of the  holders  of  Preferred  Stock of any and all  series,  to  receive  such
dividends as from time to time may be declared by the Board of Directors.

                  VI.  Except  as  otherwise   provided  by  the  resolution  or
resolutions  providing  for the issue of any series of Preferred  Stock,  in the
event of any liquidation,  dissolution of winding up of the Corporation, whether
voluntary or involuntary,  the holders of Class A and Class B Common Stock shall
be  entitled,  after  payment  shall have been made to the holders of  Preferred
Stock of the full  amount  to which  they  shall  be  entitled  pursuant  to the
resolution or resolutions  providing for the issuance of any series of Preferred
Stock,  to share,  to the exclusion of the holders of Preferred Stock of any and
all  series,   in  all  remaining  assets  of  the  Corporation   available  for
distribution to its  stockholders  ratably  according to the number of shares of
Class A and Class B Common Stock held by them.

                 VII.  The  number of  authorized  shares of any class may be
increased or decreased by the affirmative vote of the holders of a majority of
the stock of the Corporation entitled to vote.

         FIFTH: The name and mailing address of the sole incorporator are as
follows:

                           Veronica Andrews Goldberg
                           Rubin Baum Levin Constant & Friedman
                           30 Rockfeller Plaza, 29th Floor
                           New York  New York  11012

         SIXTH:

                 I.  Number  of  Directors.  The  number  of  directors  of  the
Corporation  shall not be less than three.  The exact number of directors within
the limitations  specified in the preceding sentence shall be fixed from time to
time by the Board of Directors.

<PAGE>

                 II. Classes of Directors.  The Board of Directors  shall be and
is divided  into three  classes:  Class I, Class II and Class III.  No one class
shall have more than one director  more than any other  class.  If a fraction is
contained  in the  quotient  arrived at by  dividing  the  designated  number of
directors by three,  then,  if such fraction is  one-third,  the extra  director
shall be a member of Class I, and if such  fraction  is  two-thirds,  one of the
extra  directors  shall be a member  of Class I and one of the  extra  directors
shall be a member of Class II,  unless  otherwise  provided from time to time by
resolution adopted by the Board of Directors.

                 III.  Terms of Office.  Each  director  shall  serve for a term
ending on the date of the third annual  meeting  following the annual meeting at
which such director was elected; provided, that each initial director in Class I
shall  serve for a term ending on the date of the annual  meeting in 2000;  each
initial  director  in Class II shall  serve for a term ending on the date of the
annual meeting in 2001; and each initial director in Class III shall serve for a
term ending on the date of the annual  meeting in 2002;  and  provided  further,
that  the  term  of  each  director   shall  be  subject  to  the  election  and
qualification of his successor and to his earlier death, resignation or removal.

                 IV.  Allocation  of  Directors  Among  Classes  in the Event of
Increases or Decreases in the Number of Directors.  In the event of any increase
or  decrease in the  authorized  number of  directors,  (i) each  director  then
serving as such shall nevertheless  continue as a director of the class of which
he is a member  for the full term of such  class and (ii) the newly  created  or
eliminated  directorships  resulting  from such  increase or  decrease  shall be
apportioned by the Board of Directors among the three classes of directors so as
to  ensure  that no one class  has more  than one  director  more than any other
class.  To the extent  possible,  consistent  with the foregoing rule, any newly
created  directorships shall be added to those classes whose terms of office are
to  expire  at the  latest  dates  following  such  allocation,  and  any  newly
eliminated  directorships  shall be subtracted from those classes whose terms of
offices are to expire at the earliest dates  following such  allocation,  unless
otherwise  provided  from  time to time by  resolution  adopted  by the Board of
Directors.


<PAGE>

                 V.  Quorum;  Action at  Meeting.  A  majority  of the number of
directors  fixed  pursuant to Section I above shall  constitute a quorum  except
when a vacancy or vacancies exist, whereupon a majority of the directors then in
office shall constitute a quorum for the transaction of business,  provided that
in no case shall less than  one-third of the number of directors  fixed pursuant
to  Section I above  constitute  a  quorum.  If at any  meeting  of the Board of
Directors  there shall be less than such a quorum,  a majority of those  present
may adjourn the meeting from time to time. Every act or decision done or made by
a majority of the directors  present at a meeting duly held at which a quorum is
present shall be regarded as the act of the Board of Directors  unless a greater
number  is  required  by  law,  by the  By-laws  of the  Corporation  or by this
Certificate of Incorporation.

                 VI.  Removal.  Directors of the Corporation may be removed only
for cause by the  affirmative  vote of the  holders of at least  eighty  percent
(80%) of the  combined  voting  power of all shares of the capital  stock of the
Corporation  issued  and  outstanding  and  entitled  to vote  generally  in the
election of directors, voting together as a single class.

                 VII. Vacancies. Any vacancy in the Board of Directors,  however
occurring,  including (without  limitation) a vacancy resulting from an increase
in the number of directors,  shall be filled only by a vote of a majority of the
directors  then in office,  even if less than a quorum,  or by a sole  remaining
director.  A director  elected to fill a vacancy shall be elected to hold office
until the next  election  of the class for which such  director  shall have been
chosen,  subject to the election and  qualification  of his successor and to his
earlier death, resignation or removal.

                 VIII. Preferred Stock. Notwithstanding the foregoing,  whenever
the  holders  of any  one or  more  series  of  Preferred  Stock  issued  by the
Corporation  after  approval  by the Board of  Directors  shall  have the right,
voting separately by class or series, to elect directors at an annual or special
meeting of stockholders,  the election, term of office, filling of vacancies and
other  features  of such  directorships  shall be  governed by the terms of this
Certificate  of  Incorporation  (including  such  terms as may be adopted by the
Board of Directors  pursuant to Section III of Article FOURTH of the Certificate
of  Incorporation)  applicable  thereto,  such directors so elected shall not be
divided into  classes  pursuant to this  Article  SIXTH,  and the number of such
directors  shall not be counted in  determining  the maximum number of directors
permitted  under the foregoing  provisions of this Article  SIXTH,  in each case
unless expressly provided by such terms.

                 IX. Amendments to Article. Notwithstanding any other provisions
of law, the Certificate of Incorporation or the By-laws of the Corporation,  and
notwithstanding  the fact that a lesser  percentage may be specified by law, the
affirmative vote of the holders of at least eighty percent (80%) of the combined
voting  power of all  shares of  capital  stock of the  Corporation  issued  and
outstanding and entitled to vote generally in the election of directors,  voting
together as a single  class,  shall be required to amend or repeal,  or to adopt
any provision inconsistent with, any provision of this Article SIXTH.

<PAGE>



         SEVENTH:  No directors of the Corporation shall be personally liable to
the Corporation or its stockholders for monetary damages for breach of fiduciary
duty as a director,  provided  that this Article  SEVENTH shall not eliminate or
limit the liability of a director (i) for any breach of such  director's duty of
loyalty to the  Corporation or its  stockholders,  (ii) for acts or omissions of
such  director  not in good faith or which  involve  intentional  misconduct  or
knowing  violation  of law,  (iii)  under  Section 174 of the  Delaware  General
Corporation Law, or (iv) for any transaction from which such director derived an
improper personal benefit; nor shall this Article SEVENTH eliminate or limit the
liability of a director for any act or omission occurring prior to the date this
Article SEVENTH becomes effective.

         EIGHTH:  The Board of Directors is expressly authorized to adopt, amend
and repeal the By-Laws of the Corporation.

         NINETH:  The  Corporation  shall,  to the fullest  extent  permitted by
Section 145 of the Delaware  General  Corporation Law as the same may be amended
or  supplemented,  indemnify  any and all  persons  whom it shall  have power to
indemnify from and against any and all expenses, liabilities or other matters.

         TENTH:  Whenever a compromise or arrangement  is proposed  between this
Corporation  and  its  creditors  or any  class  of  them  and/or  between  this
Corporation  and its  stockholders  or any class of them, any court of equitable
jurisdiction  within the State of Delaware may, on the  application in a summary
way of this  Corporation  or of any  creditor or  stockholder  thereof or on the
application of any receiver or receivers  appointed for this  Corporation  under
the  provisions  of  Section  291 of  Title  8 of the  Delaware  Code  or on the
application of trustees in dissolution or of any receiver or receivers appointed
for this  Corporation  under the  provisions  of  Section  279 of Title 8 of the
Delaware Code order a meeting of the creditors or class of creditors,  and/or of
the stockholders or class of stockholders of this  Corporation,  as the case may
be, to be summoned in such  manner as the said court  directs.  If a majority in
number  representing  three-fourths  in  value  of the  creditors  or  class  of
creditors,  and/or  of  the  stockholders  or  class  of  stockholders  of  this
Corporation,  as the case may be, agree to any compromise or arrangement  and to
any  reorganization  of this  Corporation as a consequence of such compromise or
arrangement,  the said  compromise of  arrangement  and the said  reorganization
shall,  if sanctioned by the court to which the said  application has been made,
be  binding  on all the  creditors  or class  of  creditors,  and/or  on all the
stockholders or class of stockholders,  of this Corporation, as the case may be,
and also on this Corporation.


<PAGE>


                    CERTIFICATE OF DESIGNATIONS, PREFERENCES

                     AND RIGHTS OF SERIES A PREFERRED STOCK

                                       OF

                              SYMBOLLON CORPORATION

The undersigned officers of Symbollon  Corporation,  a corporation organized and
existing under the General  Corporation Law of the State of Delaware,  do hereby
certify  that,   pursuant  to  authority   conferred  by  the   Certificate   of
Incorporation,  and  pursuant  to the  provisions  of Section 151 of the General
Corporation  Law of the State of  Delaware,  the Board of Directors of Symbollon
Corporation  at a meeting duly  authorized  and validly held on August 13, 1996,
adopted  a  resolution  providing  for  certain  powers,  designations,  number,
preferences  and  relative,  participating,  optional or other  rights,  and the
qualifications, limitations or restrictions thereof, of 444,444 shares of Series
A Preferred Stock, $.001 par value, which resolution is as follows:

         RESOLVED:  That  pursuant  to  Article  Fourth  of the  Certificate  of
         Incorporation  of this  Corporation,  the  Board  of  Directors  hereby
         establishes  a series  of  Preferred  Stock,  $.001 par  value,  of the
         Corporation   having  the  following  powers,   designations,   number,
         preferences  and relative,  participating,  option of or others special
         rights, and qualifications, limitations or restrictions thereof:

                Description and Designation of Series A Preferred Stock

         1.  Designation.  A  total  of  444,444  shares  of  the  Corporation's
Preferred  Stock shall be  designated  the "Series A Preferred  Stock".  As used
herein,  the  term  "Preferred  Stock"  used  without  reference  to  any  other
outstanding  series of Preferred  Stock of the  Corporation as from time to time
may be  outstanding  means  all such  outstanding  series  of the  Corporation's
Preferred  Stock,  share for share alike and without  distinction  as to series,
except as otherwise  expressly  provided for herein, or as the context otherwise
requires.

         2.       Dividends.

                  (a)  Computation of Cumulative  Dividends.  The holders of the
outstanding shares of Series A Preferred Stock shall be entitled to receive, out
of funds legally available therefor,  cumulative dividends at the annual rate of
$0.09 per share.  Cumulative  dividends on the Series A Preferred Stock shall be
payable if, as and when declared.

                  Dividends  on the Series A Preferred  Stock shall  accrue from
day to day on each share of Series A  Preferred  Stock from the date of original
issuance  of such share,  whether or not earned or  declared,  and shall  accrue
until paid.


<PAGE>



                  All numbers  relating to calculation  of cumulative  dividends
shall be subject to  equitable  adjustment  in the event of any stock  dividend,
stock split, combination, reorganization, recapitalization,  reclassification or
other similar event involving a change in the capital  structure of the Series A
Preferred  Stock.  Such  dividends  on the  Series A  Preferred  Stock  shall be
cumulative  so that if such  dividends  in  respect of any  previous  or current
annual dividend period, at the annual rate specified above,  shall not have been
paid or declared and a sum  sufficient  for the payment  thereof set apart,  the
deficiency  shall first be fully paid before any dividend or other  distribution
shall be paid or declared and set apart for the Class A Common Stock and Class B
Common Stock  (collectively,  the "Common  Stock").  Upon any  conversion of the
Series A Preferred  Stock under  Section 5 hereof,  all such  accrued and unpaid
dividends  on the  Series  A  Preferred  Stock  to and  until  the  date of such
conversion shall be forfeited and shall not be due and payable.

                  (b) Restriction on Distributions.  Except to the extent in any
instance  approval  is  provided  in writing by the holders of a majority of the
outstanding  shares of Preferred  Stock (all series acting  together as a class)
and except for any transaction  related to the Corporation's Class A Warrants or
Class B Warrants,  the  Corporation  shall not declare or pay any dividends,  or
purchase,  redeem,  retire,  or  otherwise  acquire  for value any shares of its
capital  stock (or rights,  options or warrants to purchase  such shares) now or
hereafter  outstanding,  return any capital to its stockholders as such, or make
any distributions of assets to its stockholders as such;  provided,  however, if
any such action is effected  with respect to the  Preferred  Stock,  it shall be
done  proportionately  equivalent  for the holders of all series of  outstanding
Preferred Stock.

                  Nothing herein  contained shall prevent the Corporation  from:
(i)  effecting a stock split or declaring or paying any dividend  consisting  of
shares of any class of capital stock paid to the holders of shares of such class
of capital stock; or (ii) complying with any specific  provision of the terms of
the Preferred Stock.

                  (c)  Participating  Dividends.  In the event that the Board of
Directors  of the  Corporation  shall  declare a dividend  payable upon the then
outstanding  shares of Common Stock  (other than a stock  dividend on the Common
Stock distributed  solely in the form of additional shares of Common Stock), the
holders of the Preferred Stock shall be entitled,  in addition to any cumulative
dividends to which they may be entitled under Section 2(a) hereof, to the amount
of dividends  per share of Preferred  Stock as would be declared  payable on the
largest  number  of whole  shares of  Common  Stock  into  which  each  share of
Preferred  Stock held by each holder thereof could be converted  pursuant to the
provisions of Section 5 hereof, such number determined as of the record date for
the  determination of holders of Common Stock entitled to receive such dividend,
less any dividends theretofore paid under Section 2(a) above.


<PAGE>



         3.       Liquidation, Dissolution or Winding Up.

                  (a) Treatment at  Liquidation,  Dissolution  or Winding Up. In
the event of any  liquidation,  dissolution  or winding  up of the  Corporation,
whether voluntary or involuntary, or in the event of its insolvency,  before any
distribution  or  payment is made to any  holders  of Common  Stock or any other
class or series of capital stock of the  Corporation  designated to be junior to
the Preferred  Stock,  and subject to the liquidation  rights and preferences of
any class or series of Preferred Stock designated in the future to be senior to,
or on a parity with,  the Series A Preferred  Stock with respect to  liquidation
preferences,  the holders of each share of Preferred  Stock shall be entitled to
be paid first out of the assets of the Corporation available for distribution to
holders of the Corporation's  capital stock of all classes,  whether such assets
are capital, surplus or earnings, an amount equal to the greater of:

                           (i)  $1.125  per share of Series A  Preferred  Stock,
                  plus all  accrued  but unpaid  cumulative  dividends  thereon,
                  whether or not earned or declared, or

                           (ii)  such  amount  per share of  Preferred  Stock as
                  would have been  payable had each such share of each series of
                  Preferred  Stock been  converted to Common  Stock  immediately
                  prior to such event of liquidation,  dissolution or winding up
                  pursuant to the provisions of Section 5 hereof.

                  The  amounts  set forth  above  shall be subject to  equitable
adjustment   whenever  there  shall  occur  a  stock   dividend,   stock  split,
combination, reorganization, recapitalization, reclassification or other similar
event involving a change in the capital structure of the Preferred Stock.

                  If,  upon  liquidation,  dissolution  or  winding  up  of  the
Corporation,  the assets of the  Corporation  available for  distribution to its
stockholders  shall be insufficient to pay the holders of all outstanding series
of Preferred  Stock the full amounts to which they otherwise  would be entitled,
the holders of all  outstanding  series of Preferred  Stock (which is deemed for
purposes  of this  Section  3 to be on a  parity)  shall  share  ratably  in any
distribution  of  available  assets  pro rata in  proportion  to the  respective
liquidation preference amounts which would otherwise be payable upon liquidation
with respect to the  outstanding  shares of Preferred  Stock if all  liquidation
preference  dollar amounts with respect to such shares were paid in full,  based
upon the aggregate liquidation preference dollar amounts payable upon all shares
of Preferred Stock then outstanding (the "Liquidation Formula").


<PAGE>


                  After such payment shall have been made in full to the holders
of the Preferred  Stock, or funds necessary for such payment shall have been set
aside by the  Corporation  in trust for the account of holders of the  Preferred
Stock so as to be available for such payment, the remaining assets available for
distribution shall be distributed ratably among the holders of the Common Stock.

                  (b) Distributions  Other than Cash.  Whenever the distribution
provided for in this Section shall be payable in property  other than cash,  the
value of such  distribution  shall be the fair market value of such  property as
determined  in good  faith by the Board of  Directors  of the  Corporation.  All
distributions  (including distributions other than cash) made hereunder shall be
made  pro  rata to each  series  of  Preferred  Stock  in  accordance  with  the
Liquidation Formula described in Section 3(a) above. In the event of any dispute
between the holders of the  Preferred  Stock and the  Corporation  regarding the
determination  of the  fair  market  value  of  non-cash  distributions,  at the
election  of the holders of a majority of the  outstanding  shares of  Preferred
Stock,  the  Corporation  shall engage a consulting or  investment  banking firm
selected by the Board of Directors  and approved by the holders of a majority of
the outstanding shares of Preferred Stock to prepare an independent appraisal of
the  fair  market  value  of  such  property  to be  distributed.  Each  of  the
Corporation and the holders of a majority of the outstanding shares of Preferred
Stock shall provide such approved  appraiser with a written estimate of the fair
market  value of such  property,  and the  expenses of any  appraisal  by such a
consulting  or  investment  banking  firm shall be borne by the party  whose own
written  estimate of fair market value  proves to be furthest  from that of such
consulting or investment  banking firm. In the event that the parties' estimates
of fair market value differ from that of the  consulting or  investment  banking
firm by an equal amount, then the Corporation,  on the one hand, and the holders
of the Preferred Stock, on the other, shall each pay fifty percent (50%) of such
expenses.

         4.       Voting Power

         Except as otherwise  expressly  provided in this Section 4 or Section 6
hereof or as otherwise  required by law, each holder of Series A Preferred Stock
shall be entitled to vote on all matters and shall be entitled to that number of
votes equal to the  largest  number of whole  shares of Common  Stock into which
such holder's shares of Series A Preferred Stock could be converted, pursuant to
the provisions of Section 5 hereof,  at the record date for the determination of
stockholders  entitled  to vote on such  matter  or, if no such  record  date is
established,  at the  date  such  vote  is  taken  or  any  written  consent  of
stockholders  is  solicited.  Except as  otherwise  expressly  provided  in this
instruments,  the  Certificate of  Designations,  Preferences  and Rights of any
other series of outstanding Preferred Stock or as otherwise required by law, the
holders of shares of Preferred  Stock and Common  Stock shall vote  together (or
render  written  consents  in lieu of a vote) as a single  class on all  matters
submitted to the stockholders of the Corporation.


<PAGE>



         5.       Conversion  Rights.  The holders of the Series A Preferred
Stock shall have the following rights with respect to the conversion of such
shares into shares of Class A Common Stock:

                  (a) General.  Subject to and in compliance with the provisions
of this Section 5, any shares of the Series A Preferred Stock may, at the option
of any holder,  be converted  at any time and from time to time into  fully-paid
and non-assessable shares of Class A Common Stock. The number of shares of Class
A Common  Stock which a holder of Series A Preferred  Stock shall be entitled to
receive  upon  conversion  shall be the  product  obtained  by  multiplying  the
Applicable  Conversion  Rate  (determined  as provided  in Section  5(b)) by the
number of shares of Series A Preferred Stock being converted at any time.

                  (b) Applicable  Conversion Rate. The conversion rate in effect
at any time for the Series A Preferred Stock (the "Applicable  Conversion Rate")
shall be the  quotient  obtained by dividing  $1.125 by the Series A  Applicable
Conversion  Value,  calculated  as  provided  in  Section  5(c)  (the  "Series A
Applicable Conversion Rate").

                  (c)  Applicable  Conversion  Value.  The  Series A  Applicable
Conversion  Value in effect from time to time,  except as adjusted in accordance
with Section 5(d) hereof, shall be $1.125 with respect to the Series A Preferred
Stock (the "Series A Applicable Conversion Value").

                  (d)  Adjustments to Series A Applicable Conversion Value.

                      (i) Closing Bid Price.  At any time after August 14, 1997,
if at the  time of conversion the average Closing Bid Price (as hereinafter
defined) of the Class A Common  Stock of the  Corporation  for the  immediately
preceding  twenty (20) consecutive trading  days (the  "Twenty-Day  Average") is
below the Series A Applicable  Conversion Value then in  effect, then the Series
A Applicable Conversion Value relevant only for the shares of Series A Preferred
Stock being then converted shall  automatically be adjusted immediately prior to
conversion to equal 83.33% of the Twenty-Day Average.  The preceding  adjustment
to the Series A Applicable Conversion Value relevant to the shares being then
converted shall not adjust or otherwise effect the Series A Applicable
Conversion Value of the remaining outstanding shares of Series A Preferred
Stock.

                  The  "Closing  Bid Price" shall mean (1) if the Class A Common
Stock is then listed on any  national  securities  exchange,  the closing  sales
price on the principal  national  securities  exchange on which it is so traded,
(2) if the Class A Common  Stock is not then  listed on any such  exchange,  the
closing  bid  price on the  over-the-counter  market  as  reported  by  NASDAQ's
National Market System or Small Capitalization System ("NASDAQ"),  or (3) if the
Class A Common  Stock is not then  listed  on any such  exchange  or  quoted  in
NASDAQ, the average of the closing bids on the National Daily Quotation Service.
If for any trading day the Class A Common Stock is listed on any


<PAGE>



 such  exchange,
or quoted in NASDAQ or National Daily  Quotation  Service and the actual Closing
Bid  Price is not  determinable  in  accordance  with the  above,  then for such
trading day the Closing Bid Price shall be the last immediately reported Closing
Bid Price.  If the Class A Common Stock is not listed on any such  exchange,  or
quoted in NASDAQ or  National  Daily  Quotation  Service,  the Closing Bid Price
shall be determined in good faith by the Board of Directors of the Corporation.

                      (ii) Upon Extraordinary Common Stock Event.  Upon the
happening of an Extraordinary Common Stock Event (as hereinafter defined),  the
Series A Applicable Conversion Value shall,  simultaneously  with the  happening
of such  Extraordinary Common Stock Event, be adjusted by multiplying the Series
A Applicable Conversion Value by a fraction, the numerator of which shall be the
number of shares of Common Stock outstanding immediately prior to such
Extraordinary Common Stock Event and the denominator of which shall be the
number of shares of Common Stock outstanding immediately after such
Extraordinary Common Stock Event, and the product so  obtained  shall thereafter
be the Series A Applicable Conversion Value.  The Series A Applicable Conversion
Value, as so adjusted, shall be readjusted in the same manner upon the happening
of any successive Extraordinary Common Stock Event or Events.

                  An "Extraordinary Common Stock Event" shall mean (I) the issue
of  additional  shares of Common  Stock as a dividend or other  distribution  on
outstanding  shares of Common Stock, (ii) a subdivision of outstanding shares of
Common  Stock  into a greater  number of  shares  of  Common  Stock,  or (iii) a
combination or reverse stock split of outstanding  shares of Common Stock into a
smaller number of shares of the Common Stock.

                  (e)      Automatic Conversion.

                      (i) Mandatory Conversion of Preferred  Stock.  Immediately
upon (1) the effectiveness of an underwritten public offering on a firm
commitment basis pursuant to an effective registration  statement filed pursuant
to the Securities Act of 1933, as amended, covering the offer and sale of Common
Stock for the account of the Corporation in which the Corporation actually
receives gross proceeds equal to or greater than $5,000,000 (calculated after
deducting  underwriters' discounts and commissions but before calculation of
expenses), and in which the price per share of Common Stock equals or exceeds
$3.00 (such price  subject to equitable adjustment  in the  event  of any  stock
dividend, stock split, combination, reorganization, recapitalization,
reclassification or other similar event involving a change in the Common Stock),
(2) the approval, set forth in a written notice to the Corporation, of the
holders of at least a majority of the outstanding  shares of Series A Preferred
Stock of an election to convert Series A Preferred Stock into Class A Common
Stock, or (3) August 14, 2001, then all outstanding shares of Series A Preferred
Stock shall be converted automatically into the number of shares of Class A
Common  Stock  into  which  such  shares of Series A Preferred Stock are then
convertible pursuant to Section 5


<PAGE>



 hereof as of the closing and consummation of
such  underwritten  public offering, the stated date of approval of such holders
of Series A Preferred Stock or August 14, 2001, without any further action by
the holders of such shares and whether or not the certificates representing such
shares are surrendered to the Corporation or its transfer agent.

                      (ii) Surrender of Certificates Upon Mandatory  Conversion.
Upon the occurrence of the conversion events specified in the preceding
paragraph (i), the holders of the Series A Preferred Stock shall, upon notice
from the Corporation, surrender the certificates representing such shares at the
office of the Corporation or of its transfer  agent for the Common Stock.
Thereupon,  there shall be issued and delivered to such holder a certificate or
certificates for the number of shares of Class A Common Stock into which the
shares of Series A  Preferred  Stock so surrendered were convertible on the date
on which such conversion occurred.  The Corporation  shall not  be obligated  to
issue  such certificates  unless certificates  evidencing the shares of Series A
Preferred Stock being converted are either  delivered to the Corporation or any
such transfer agent, or the holder notifies the Corporation that such
certificates have been lost, stolen or destroyed and executes an agreement
satisfactory to the Corporation to indemnify the Corporation from any loss
incurred by it in connection therewith.

                  (f)  Dividends.  In the event the  Corporation  shall  make or
issue,  or shall fix a record  date for the  determination  of holders of Common
Stock  entitled  to  receive a  dividend  or other  distribution  (other  than a
distribution in liquidation or other distribution otherwise provided for herein)
with respect to the Common Stock payable in (i)  securities  of the  Corporation
other  than  shares  of Common  Stock,  or (ii)  other  assets  (excluding  cash
dividends or distributions), then and in each such event provision shall be made
so that  the  holders  of the  Series  A  Preferred  Stock  shall  receive  upon
conversion  thereof  in  addition  to the  number  of  shares  of  Common  Stock
receivable  thereupon,  the number of  securities  or such  other  assets of the
Corporation  which they would have  received had their Series A Preferred  Stock
been  converted  into  Common  Stock  on the  date of such  event  and had  they
thereafter,  during the period from the date of such event to and  including the
Conversion  Date (as that term is hereafter  defined in Section 5(j)),  retained
such  securities  or such other  assets  receivable  by them during such period,
giving  application to all other adjustments called for during such period under
this  Section 5 with  respect  to the  rights  of the  holders  of the  Series A
Preferred Stock.

                  (g) Capital Reorganization or Reclassification.  If the Common
Stock  issuable  upon the  conversion  of the Series A Preferred  Stock shall be
changed into the same or  different  number of shares of any class or classes of
capital   stock,   whether   by   capital   reorganization,    recapitalization,
reclassification or otherwise (other than a subdivision or combination of shares
or stock  dividend  provided for elsewhere in this Section 5, or the sale of all
or substantially all of the  Corporation's  capital stock or assets to any other
person),  than and in each  such  event  the  holder  of each  share of


<PAGE>



 Series A
Preferred  Stock shall have the right  thereafter to convert such share into the
kind and amount of shares of capital  stock and other  securities  and  property
receivable upon such reorganization, recapitalization, reclassification or other
change by the  holders of the  number of shares of Common  Stock into which such
shares of Series A Preferred Stock might have been converted  immediately  prior
to  such  reorganization,  recapitalization,  reclassification  or  change,  all
subject to further adjustment as provided herein.

                  (h) Capital  Reorganization,  Merger or Sale of Assets.  If at
any time or from time to time  there  shall be a capital  reorganization  of the
Common  Stock  (other  than  a   subdivision,   combination,   recapitalization,
reclassification or exchange of shares provided for elsewhere in this Section 5)
or a merger or consolidation of the Corporation with or into another corporation
(other than a merger or  reorganization  involving only a change in the state of
incorporation  of the  Corporation  or the  acquisition  by the  Corporation  of
another business where the Corporation  survives as a going concern,  as further
provided in Section 3 hereof),  or the sale of all or  substantially  all of the
Corporation's  capital stock or assets to any other  person,  then, as a part of
such  reorganization,  merger, or consolidation or sale, provision shall be made
so that the holders of the Series A Preferred Stock shall thereafter be entitled
to receive upon  conversion of the Series A Preferred Stock the number of shares
of stock or other securities or property (including cash) of the Corporation, or
of the successor corporation resulting from such merger,  consolidation or sale,
to which such holder would have been  entitled if such holder had  converted its
shares  of  Series  A  Preferred  Stock   immediately   prior  to  such  capital
reorganization,  merger,  consolidation  or sale. In any such case,  appropriate
adjustment  shall be made in the application of the provisions of this Section 5
to the end that the  provisions  of this Section 5 (including  adjustment of the
Series A Applicable  Conversion Value then in effect and the number of shares of
Common Stock or other  securities  issuable  upon  conversion  of such shares of
Series A  Preferred  Stock)  shall be  applicable  after that event in as nearly
equivalent a manner as may be practicable.

                  The holders of at least a majority of the  outstanding  shares
of Preferred Stock, upon the occurrence of a capital  reorganization,  merger or
consolidation  of the Corporation,  or the sale of all or substantially  all its
capital  stock or assets,  as such  events are more fully set forth in the first
paragraph of this Section 5(h), shall have the option of electing  treatment for
the  Preferred  Stock as would be required for an event covered under either (i)
this Section 5(h) or (ii) Section 3 hereof regard a liquidation,  dissolution or
winding up of the affairs of the Corporation,  notice of which election shall be
submitted in writing to the  Corporation  at its principal  office no later than
twenty (20) business days before the effective date of such event.

                  (i) Certificate as to Adjustments;  Notice by Corporation.  In
each case of an adjustment or readjustment of the Series A Applicable Conversion
Rate,  the  Corporation  at its  expense  will  furnish  each holder of Series A
Preferred  Stock so affected  with a  certificate  prepared by the  Treasurer or
Chief  Financial  Officer  of  the


<PAGE>



  Corporation,   showing  such  adjustment  or
readjustment,  and  stating in detail the facts  upon which such  adjustment  or
readjustment is based.

                  (j)  Exercise  of  Conversion   Privilege.   To  exercise  its
conversion  privilege,  a holder of Series A Preferred Stock shall surrender the
certificate  or  certificates  representing  the shares  being  converted to the
Corporation  at its  principal  office,  and shall  give  written  notice to the
Corporation at that office that such holder elects to convert such shares.  Such
notice shall also state the name or names (with  address or  addresses) in which
the certificate or certificates for shares of Class A Common Stock issuable upon
such conversion  shall be issued.  The certificate or certificates for shares of
Series A Preferred  Stock  surrendered  for  conversion  shall be accompanied by
proper  assignment  thereof to the  Corporation or in blank.  The date when such
written notice is received by the Corporation,  together with the certificate or
certificates   representing  the  shares  of  Series  A  Preferred  Stock  being
converted,  shall be the "Conversion Date". As promptly as practicable after the
Conversion Date, the Corporation  shall issue and shall deliver to the holder of
the shares of Series A Preferred Stock being converted, or on its written order,
such  certificate  or  certificates  as it may  request  for the number of whole
shares of Class A Common Stock  issuable  upon the  conversion of such shares of
Series A Preferred  Stock in accordance  with the  provisions of this Section 5,
and cash,  as provided in Section 5(k), in respect of any fraction of a share of
Class A Common Stock issuable upon such  conversion.  Such  conversion  shall be
deemed to have been effected  immediately  prior to the close of business on the
Conversion  Date,  and at such time the  rights  of the  holder as holder of the
converted  shares of Series A Preferred  Stock shall cease and the  person(s) in
whose  name(s) any  certificate(s)  for shares of Class A Common  Stock shall be
issuable  upon such  conversion  shall be deemed to have  become  the  holder or
holders of record of the shares of Class A Common Stock represented thereby.

                  (k) Cash in Lieu of Fractional Shares. No fractional shares of
Class A Common  Stock or scrip  representing  fractional  shares shall be issued
upon the  conversion  of shares  of Series A  Preferred  Stock.  Instead  of any
fractional shares of Class A Common Stock which would otherwise be issuable upon
conversion of Series A Preferred Stock, the Corporation  shall pay to the holder
of the shares of Series A Preferred Stock which were converted a cash adjustment
in respect of such fractional  shares in an amount equal to the same fraction of
the  market  price  per share of the Class A Common  Stock (as  determined  in a
reasonable manner prescribed by the Board of Directors) at the close of business
on the Conversion  Date. The  determination  as to whether or not any fractional
shares are issuable shall be based upon the aggregate number of shares of Series
A Preferred  Stock being  converted at any one time by any holder  thereof,  not
upon each share of Series A Preferred Stock being converted.


<PAGE>



                  (l) Partial  Conversion.  In the event some but not all of the
shares of Series A Preferred Stock  represented by a certificate(s)  surrendered
by a holder are converted,  the  Corporation  shall execute and deliver to or on
the order of the holder,  at the expense of the  Corporation,  a new certificate
representing  the number of shares of Series A  Preferred  Stock  which were not
converted.

                  (m) Reservation of Common Stock. The Corporation  shall at all
times reserve and keep available out of its  authorized  but unissued  shares of
Class A Common Stock,  solely for the purpose of effecting the conversion of the
shares of the Series A  Preferred  Stock,  such  number of its shares of Class A
Common Stock as shall from time to time be sufficient  to effect the  conversion
of all outstanding  shares of the Series A Preferred Stock (including any shares
of Series A Preferred Stock represented by any warrants,  options,  subscription
or purchase rights for Series A Preferred Stock),  and if at any time the number
of  authorized  but  unissued  shares  of  Class A  Common  Stock  shall  not be
sufficient to effect the conversion of all then outstanding shares of the Series
A Preferred Stock (including any shares of Series A Preferred Stock  represented
by any warrants,  options,  subscriptions  or purchase  rights for such Series A
Preferred Stock),  the Corporation shall take such action as may be necessary to
increase  its  authorized  but  unissued  shares of Class A Common Stock to such
number of shares as shall be sufficient for such purpose.

                  (n)  Reissuance  of  Preferred  Stock.  No share or  shares of
Series A Preferred  Stock  acquired by the  Corporation by reason of redemption,
purchase, conversion or otherwise shall be reissued as Series A Preferred Stock,
but all such  shares  shall be  considered  authorized  but  unissued  shares of
Preferred Stock.

         6.       Restrictions and Limitations.

                  (a) Corporate Action;  Amendments to Charter.  The Corporation
shall not take any  corporate  action or  otherwise  amend  its  Certificate  of
Incorporation  without the approval by vote or written consent of the holders of
at least a majority of the then outstanding  shares of Preferred  Stock,  voting
together as a single class,  each share of Preferred Stock to be entitled to one
vote in each instance,  if such corporate  action or amendment would  materially
adversely  affect any of the rights,  preferences,  privileges of or limitations
provided  for  herein  for the  benefit  of any  shares  of  Preferred  Stock or
otherwise materially adversely affect the rights of the holders of the Preferred
Stock.   Without  limiting  the  generality  of  the  preceding  sentence,   the
Corporation  will not amend its Certificate of  Incorporation  or take any other
corporate  action  without the approval by the holders of at least a majority of
the then  outstanding  shares of Preferred  Stock,  voting  together as a single
class, if such amendment or corporate action would:


<PAGE>



                           (i) authorize or issue,  or obligate the  Corporation
                           to authorize or issue, additional shares of Preferred
                           Stock  senior  to or on a parity  with the  Preferred
                           Stock  with  respect  to   liquidation   preferences,
                           dividend rights or redemption rights,  except for the
                           designation and issuance of shares of Preferred Stock
                           approved in any instance by the holders of a majority
                           of the outstanding shares of Preferred Stock; or

                           (ii)  reduce the amount payable to the holders of
                           Preferred Stock upon the voluntary or involuntary
                           liquidation, dissolution or winding up of the
                           Corporation; or

                           (iii) adversely  affect the liquidation  preferences,
                           dividend rights,  voting rights or redemption  rights
                           of the holders of Preferred Stock; or

                           (iv) cancel or adversely modify the conversion rights
                           of the holders of  Preferred  Stock  provided  for in
                           Section 5 herein.

         7. No Dilution or Impairment. The Corporation will not, by amendment of
its  Certificate of  Incorporation  or through any  reorganization,  transfer of
capital stock or assets,  consolidation,  merger, dissolution,  issue or sale of
securities or any other voluntary action,  avoid or seek to avoid the observance
or performance of any of the terms of the Preferred Stock set forth herein,  but
will at all times in good faith assist in the carrying out of all such terms and
in the taking of all such action as may be necessary or  appropriate in order to
protect the rights of the holders of the  Preferred  Stock  against  dilution or
other  impairment.  Without  limiting  the  generality  of  the  foregoing,  the
Corporation  (a)  will  not  increase  the par  value  of any  shares  of  stock
receivable on the  conversion of the  Preferred  Stock above the amount  payable
therefor  on such  conversion,  and (b)  will  take all  such  action  as may be
necessary or appropriate in order that the  Corporation  may validly and legally
issue  fully paid and  nonassessable  shares of stock on the  conversion  of all
Preferred Stock from time to time outstanding.

         8.       Notices of Record Date.   In the event of:

                  (a) any taking by the  Corporation  of a record of the holders
of any class of securities  for the purpose of determining  the holders  thereof
who are entitled to receive any dividend or other distribution,  or any right to
subscribe for,  purchase or otherwise acquire any shares of capital stock of any
class or any other securities or property, or to receive any other right, or


<PAGE>



                  (b)  any  capital  reorganization  of  the  Corporation,   any
reclassification  or  recapitalization  of the capital stock of the Corporation,
any  merger or  consolidation  of the  Corporation,  or any  transfer  of all or
substantially all of the assets of the Corporation to any other corporation,  or
any other entity or person, or

                  (c) any voluntary or involuntary dissolution, liquidation or
winding up of the Corporation,

then and in each such event the Corporation  shall mail or cause to be mailed to
each  holder of Series A  Preferred  Stock a notice  specifying  (i) the date on
which  any  such  record  is to be  taken  for the  purpose  of  such  dividend,
distribution or right and a description of such dividend, distribution or right,
(ii)   the   date  on   which   any   such   reorganization,   reclassification,
recapitalization,  transfer, consolidation,  merger, dissolution, liquidation or
winding up is expected to become effective,  and (iii) the time, if any, that is
to be  fixed,  as to when the  holders  of  record  of  Common  Stock  (or other
securities) shall be entitled to exchange their shares of Common Stock (or other
securities)   for   securities   or  other   property   deliverable   upon  such
reorganization,  reclassification,  recapitalization,  transfer,  consolidation,
merger,  dissolution,  liquidation or winding up. Such notice shall be mailed by
first  class  mail,  postage  prepaid,  at least ten (10) days prior to the date
specified in such notice on which such action is to be taken.




                                                                     Exhibit 3.2
                                     BY-LAWS
                                       OF
                              SYMBOLLON CORPORATION
                                    ARTICLE I
                                     OFFICES
         Section 1. REGISTERED  OFFICE;  REGISTERED AGENT. The registered office
shall be located at 32  Loockerman  Square,  Suite L-100,  in the city of Dover,
County of Kent,  State of  Delaware.  The name of the  registered  agent at such
address is the Prentice-Hall Corporation System, Inc.

         Section 2. OTHER OFFICES. The corporation may also have offices at such
other  places  both  within and  without  the State of  Delaware as the board of
directors may from time to time determine or the business of the corporation may
require.

                                   ARTICLE II
                            MEETINGS OF STOCKHOLDERS


         Section 1. PLACE. Annual Meetings and special meetings shall be held at
such place, within or without the State of Delaware,  as the directors may, from
time to time,  fix.  Whenever the  directors  shall fail to fix such place,  the
meeting shall be held at the registered  office of the  corporation in the State
of Delaware.

         Section 2. TIME. Annual meetings of stockholders  shall be held on such
date and at such time as the  directors  may,  from time to time,  fix.  Special
meetings shall be held on the date and at the time fixed by the directors.

         Section 3. BUSINESS TO BE  TRANSACTED.  The  stockholders  at an annual
meeting  shall elect  directors  and transact any other proper  business to come
before the meeting.  The  stockholders  at any special  meeting of  stockholders
shall transact any proper business to come before the meeting.

         Section 4.  CALL.  Annual meetings and special meetings may be called
by the directors or by any officer authorized by the directors to call the
meeting.


<PAGE>




         Section 5. NOTICE AND WAIVER OF NOTICE.  Written notice of all meetings
shall be given,  stating the place, date and hour of the meeting and stating the
place at which the list of stockholders of the corporation may be examined.  The
notice of an annual  meeting  shall  state  that the  meeting  is called for the
election  of  directors  and for the  transaction  of other  business  which may
properly come before the meeting.  The notice of a special  meeting shall in all
instances state the purpose or purposes for which the meeting is called.  If any
action is proposed to be taken which would,  if taken,  entitle  stockholders to
receive payment for their shares of stock,  the notice shall include a statement
of that purpose and to that effect. Except as otherwise provided by the Delaware
General  Corporation  Law, a copy of the notice of any  meeting  shall be given,
personally  or by mail,  not less than ten days nor more than sixty days  before
the date of the meeting, unless the lapse of the prescribed period of time shall
have been waived,  and directed to each  stockholder at his record address or at
such  other  address  which he may have  furnished  by request in writing to the
Secretary  of the  Corporation.  Notice by mail shall be deemed to be given when
deposited, with postage thereon prepaid, in the United States mail. If a meeting
is adjourned to another time, not more than thirty days hence, and/or to another
place,  and if an announcement of the adjourned time and/or place is made at the
meeting,  it shall not be  necessary  to give  notice of the  adjourned  meeting
unless the directors after adjournment,  fix a new record date for the adjourned
meeting.  Notice  need not be  given  to any  stockholder  who in  person  or by
attorney thereunto authorized,  submits a waiver of notice by him in writing, or
by  telegraph,  cable or  wireless,  before  or after the time  stated  therein.
Attendance of a person at a meeting shall  constitute a waiver of notice of such
meeting,  except when the stockholder  attends a meeting for the express purpose
of  objecting,  at the  beginning  of the  meeting,  to the  transaction  of any
business  because the meeting is not lawfully  called or  convened.  Neither the
business to be transacted at, nor the purpose of, any regular or special meeting
of the stockholders need be specified in any written waiver of notice.

         Section 6.  STOCKHOLDER  LIST.  The officer who has charge of the stock
ledger of the corporation shall prepare and make, at least ten days before every
meeting of stockholders, a complete list of the stockholders entitled to vote at
the meeting,  arranged in  alphabetical  order,  and showing the address of each
stockholder and the number of shares registered in the name of each stockholder.
Such list shall be open to the examination of any  stockholder,  for any purpose
germane to the meeting,  during the ordinary  business hours, for a period of at
least ten days prior to the meeting,  either at a place within the city or other
municipality or community where the meeting is to be held,  which place shall be
specified in the notice of the  meeting,  or if not so  specified,  at the place
where the meeting is to be held. The list shall also be produced and kept at the
time and  place  of the  meeting  during  the  whole  time  thereof,  and may be
inspected by any  stockholder  who is present.  The original or duplicate  stock
ledger  shall be the only  evidence as to who are the  stockholders  entitled to
examine the stock ledger,  the list required by this section or the books of the
corporation, or to vote at any meeting of stockholders.


<PAGE>


         Section 7.  QUORUM.  The  holders of a majority  of the  capital  stock
issued  and  outstanding  and  entitled  to vote  thereat,  present in person or
represented  by  proxy,  shall  constitute  a  quorum  at  all  meetings  of the
stockholders  for the  transaction of business  except as otherwise  provided by
statute or by the Certificate of Incorporation.  If, however,  such quorum shall
not  be  present  or  represented  at  any  meeting  of  the  stockholders,  the
stockholders  entitled  to vote  thereat,  present in person or  represented  by
proxy, shall have power to adjourn the meeting from time to time, until a quorum
shall be present or represented.  When a meeting is adjourned to another time or
place,  notice need not be given of the adjourned  meeting if the time and place
thereof are announced at the meeting at which  adjournment is taken. At any such
adjourned  meeting  at  which a quorum  shall be  present  or  represented,  any
business  may be  transacted  which might have been  transacted  at the original
meeting.  If the  adjournment  is for more  than  thirty  days,  or if after the
adjournment  a new record date is fixed for the adjourned  meeting,  a notice of
the adjourned  meeting shall be given to each  stockholder of record entitled to
vote at the meeting.

         Section 8. VOTING.  Except as otherwise  provided in the Certificate of
Incorporation, at every meeting of the stockholders, each stockholder having the
right to vote shall be entitled to one vote in person or by proxy for each share
of the capital  stock  having  voting  power held by such stock  holder.  In the
election of  directors,  a plurality  of the votes cast shall  elect.  Any other
action  shall be  authorized  by a majority of the votes cast  except  where the
Delaware   General   Corporation  Law  or  the   corporation's   Certificate  of
Incorporation  prescribes  a different  percentage  of votes  and/or a different
exercise of voting power.  In the election of  directors,  voting need not be by
ballot.  Voting by ballot shall not be required for any other  corporate  action
except as otherwise provided by the General Corporation Law.

         Section  9.  PROXY  REPRESENTATION.  Every  stockholder  may  authorize
another  person or  persons  to act for him by proxy in all  matters  in which a
stockholder  is  entitled  to  participate,  whether  by  waiving  notice of any
meeting,  voting or participating at a meeting, or expressing consent or dissent
without a  meeting.  Every  proxy  must be signed by the  stockholder  or by his
attorney-in-fact.  No proxy  shall be voted or acted upon after three years from
its date unless such proxy provides for a longer  period.  A duly executed proxy
shall be irrevocable  if it states that it is  irrevocable  and, if, and only as
long  as,  it is  coupled  with an  interest  sufficient  in law to  support  an
irrevocable  power.  A proxy may be made  irrevocable  regardless of whether the
interest  with  which it is  coupled is an  interest  in the stock  itself or an
interest in the corporation generally.


<PAGE>


         Section  10.  RECORD  DATE  FOR   STOCKHOLDERS.   For  the  purpose  of
determining the stockholders  entitled to notice of or to vote at any meeting of
stockholders  or any  adjournment  thereof,  or to express consent to or dissent
from any corporate  action in writing  without a meeting,  or for the purpose of
determining  stockholders  entitled to receive  payment of any dividend or other
distribution or the allotment of any rights,  or entitled to exercise any rights
in respect of any change,  conversion,  or exchange of stock, or for the purpose
of any other lawful  action,  the directors  may fix, in advance,  a date as the
record date for any such  determination of stockholders.  Such date shall not be
more than sixty days nor less than ten days before the date of such meeting, nor
more than sixty days prior to any other action.  If no record date is fixed, the
record date for the  determination  of stockholders  entitled to notice of or to
vote at a meeting of  stockholders  shall be at the close of business on the day
next preceding the day on which notice is given, or, if notice is waived, at the
close of  business  on the day next  preceding  the day on which the  meeting is
held; the record date for determining  stockholders  for any other purpose shall
be at the close of business on the day on which the board of directors adopt the
resolution  relating  thereto.  When a  determination  of stockholders of record
entitled  to notice of or to vote at any  meeting  of  stockholders  has been as
provided in this paragraph,  such  determination  shall apply to any adjournment
thereof;  provided,  however,  that the board of directors  may fix a new record
date for the adjourned meeting.

         Section 11. CONDUCT OF MEETINGS.  Meetings of the stockholders shall be
presided over by one of the following  officers in the order of seniority and if
present and  acting:  the  Chairman  of the Board,  if any,  the  President,  an
Executive Vice President,  a Vice President,  or, if none of the foregoing is in
office and present and acting,  by a Chairman to be chosen by the  stockholders.
The Secretary of the  corporation,  or in his absence,  an Assistant  Secretary,
shall act as secretary of every  meeting,  but if neither the  Secretary  nor an
Assistant  Secretary  is present,  the Chairman of the meeting  shall  appoint a
secretary of the meeting.


<PAGE>


         Section 12.  INSPECTOR  AND JUDGES.  The  directors,  in advance of any
meeting, may, but need not, appoint one or more inspectors of election or judges
of the  vote,  as the  case may be,  to act at the  meeting  or any  adjournment
thereof. If an inspector or inspectors or judge or judges are not appointed, the
person  presiding  at the  meeting  may,  but  need  not,  appoint  one or  more
inspectors or judges. In case any person who may be appointed as an inspector or
judge fails to appear or act, the vacancy may be filled by  appointment  made by
the  directors  in  advance  of the  meeting  or at the  meeting  by the  person
presiding  thereat.  Each inspector or judge,  if any,  before entering upon the
discharge of his duties,  shall take and sign an oath  faithfully to execute the
duties of  inspector  or judge at such  meeting  with  strict  impartiality  and
according to the best of his ability.  The inspectors or judges, if any, and, if
there are none,  the person  presiding  shall  determine the number of shares of
stock  outstanding and the voting power of each, the shares of stock represented
at the meeting,  the existence of a quorum,  the validity and effect or proxies,
and shall receive votes, ballots or consents,  hear and determine all challenges
and questions  arising in connection with the right to vote,  count and tabulate
all votes,  ballots or consents,  determine the result,  and do such acts as are
proper to conduct the  election or vote with  fairness to all  stockholders.  On
request of the person  presiding at the meeting,  the inspector or inspectors or
judge or  judges,  if any,  shall  make a report in  writing  of any  challenge,
question or matter  determined by him or them and execute a  certificate  of any
fact found by him or them.

         Section 13. STOCKHOLDER ACTION WITHOUT MEETINGS. Any action required to
or which may be taken at any annual or special meeting of  stockholders,  may be
taken  without a meeting,  without prior notice and without a vote, if a consent
in writing, setting forth the action so taken, shall be signed by the holders of
outstanding stock having not less than the minimum number of votes that would be
necessary  to  authorize  or take such  action at a meeting  at which all shares
entitled to vote therein were present and voted.  Prompt notice of the taking of
the  corporate  present and voted.  Prompt notice of the taking of the corporate
action without a meeting by less than unanimous  written  consent shall be given
to those stockholders who have not consented in writing.

                                   ARTICLE III

                                    DIRECTORS

         Section 1. FUNCTIONS AND  DEFINITION.  The business of the  corporation
shall be managed by the board of  directors of the  corporation.  The use of the
phrase "whole  board"  herein refers to the total number of directors  which the
corporation would have if there were no vacancies.

         Section  2.  QUALIFICATIONS  AND  NUMBER.  A  director  need  not  be a
stockholder,  a citizen of the  United  States,  or a  resident  of the State of
Delaware.  Unless otherwise set forth in the Certificate of  Incorporation,  the
number of directors  shall be determined  from time to time by resolution of the
board of directors.


<PAGE>



         Section 3. CLASSIFICATION OF DIRECTORS; ELECTION AND TERM. The board of
directors  shall be and is  divided  into three  classes:  Class I, Class II and
Class III.  No one class shall have more than one  director  more than any other
class.  If a fraction is contained  in the  quotient  arrived at by dividing the
designated number of directors by three, then if such fraction is one third, the
extra director shall be a member of Class I, and if such fraction is two-thirds,
one of the  extra  directors  shall be a member  of Class I and one of the extra
directors shall be a member of Class II, unless otherwise  provided from time to
time by resolution adopted by the board of directors.  Each director shall serve
for a term  ending  on the date of the  third  annual  meeting  of  stockholders
following the annual meeting of stockholders at which such director was elected;
provided, that each initial director in Class I shall serve for a term ending on
the date of the annual meeting of stockholders in 2000; each initial director in
Class II shall  serve for a term  ending on the date of the  annual  meeting  of
stockholders  in 2001, and each initial  director in Class III shall serve for a
term  ending on the date of the annual  meeting  of  stockholders  in 2002;  and
provided  further,  that  the term of each  director  shall  be  subject  to the
election  and   qualification  of  his  successor  and  to  his  earlier  death,
resignation  or  removal.  In the  event  of any  increase  or  decrease  in the
authorized  number of  directors,  (i) each  director then serving as such shall
nevertheless continue as a director of the class of which he is a member for the
full term of such class and (ii) the newly created or  eliminated  directorships
resulting  from such increase or decrease  shall be  apportioned by the board of
directors  among the three  classes of a  directors  so as to ensure that no one
class  has more than one  director  more than any  other  class.  To the  extent
possible,  consistent with the foregoing  rule, any newly created  directorships
shall be added to those  classes  whose  terms of  office  are to  expire at the
latest dates following such allocation,  and any newly eliminated  directorships
shall be  subtracted  from those classes whose terms of offices are to expire at
the earliest dates following such  allocation,  unless  otherwise  provided from
time to time by resolution adopted by the board of directors. Any vacancy in the
board of directors, however occurring,  including (without limitation) a vacancy
resulting from an increase in the number of directors, shall be filled only by a
vote of a majority of the directors then in office, although less than a quorum,
or by a sole remaining  director.  A director elected to fill a vacancy shall be
elected  to hold  office  until the next  election  of the class for which  such
director shall have been chosen,  subject to the election and  qualification  of
his successor and to his earlier death, resignation or removal.  Notwithstanding
the foregoing, whenever the holders of any one or more series of Preferred Stock
issued by the  Corporation  after approval by the Board of Directors  shall have
the right, voting separately by class or series, to elect directors at an annual
or special meeting of  stockholders,  the election,  term of office,  filling of
vacancies  and other  features  of such  directorships  shall be governed by the
terms  of the  Certificate  of  Incorporation  (including  such  terms as may be
adopted by the Board of Directors  pursuant to Section III of Article  FOURTH of
the Certificate of Incorporation)  applicable thereto, such directors so elected
shall not be divided into classes  pursuant to this Article III,  Section 3, and
the number of such  directors  shall not be counted in  determining  the maximum
number of directors  permitted  under the  foregoing  provisions of this Article
III, Section 3, in each case unless expressly provided by such terms.

<PAGE>

         Section 4.  MEETINGS.

                  (a) - TIME. Regular meetings shall be held at such time as the
board shall fix, except that the first meeting of a newly elected board shall be
held as soon after its  election as the  directors  may  conveniently  assemble.
Special  meetings shall be held at such time as the parties calling such meeting
shall specify in the notice of meeting.

                  (b) - PLACE.  Meetings  shall be held at such place  within or
without the State of Delaware as shall be fixed by the board.

                  (c) - CALL. No call shall be required for regular meetings for
which the time and place have been fixed.  Special  meetings may be called by or
at the direction of the Chairman of the Board,  if any, the  President,  or of a
majority of the directors in office.

                  (d) - NOTICE OF ACTUAL OR CONSTRUCTIVE WAIVER. No notice shall
be required  for regular  meetings for which the time and place have been fixed.
Written,  oral, or any other mode of notice of the time and place shall be given
for  special  meetings  two  days or less  prior  to the  date of such  meeting,
provided notice is given in sufficient  time for the convenient  assembly of the
directors thereat. The notice of any meeting need not specify the purpose of the
meeting.  Any requirement of furnishing a notice shall be waived by any director
who  submits  a waiver of such  notice in  writing,  or by  telegraph,  cable or
wireless, before or after the time stated therein.

                  (e) - QUORUM AND  ACTION.  A majority of the whole board shall
constitute  a quorum  except  when a vacancy or  vacancies  exist,  whereupon  a
majority of the directors in office shall  constitute a quorum,  provided,  that
such majority shall constitute at least one-third of the whole board. A majority
of the  directors  present,  whether or not a quorum is  present,  may adjourn a
meeting to another time and place, without notice other than announcement at the
meeting.  Except as herein otherwise provided,  and except as otherwise provided
by the General Corporation Law and Certificate of Incorporation,  the act of the
board  shall be the act by vote of a  majority  of the  directors  present  at a
meeting, a quorum being present.  The quorum and voting provisions herein stated
shall  not be  construed  as  conflicting  with any  provisions  of the  General
Corporation  Law, the Certificate of Incorporation or these By-Laws which govern
a meeting of directors held to fill vacancies and newly created directorships in
the board.
                  (f) - CHAIRMAN OF THE MEETING.  The Chairman of the Board,  if
any, and if present and acting,  shall preside at all meetings.  Otherwise,  the
President,  if present and acting,  or any other  director  chosen by the board,
shall preside.

         Section 5. REMOVAL OF DIRECTORS.  Directors of the  Corporation  may be
removed only for cause by the affirmative vote of the holders of at least eighty
percent (80%) of the combined voting power of all shares of the capital stock of
the  Corporation  issued and  outstanding  and entitled to vote generally in the
election of directors, voting together as a single class.


<PAGE>


         Section 6. COMMITTEES. The board of directors may, by resolution passed
by a  majority  of the  whole  board,  designate  one or more  committees,  each
committee  to consist of two or more of the  directors of the  corporation.  The
board may designate one or more directors as alternate members of any committee,
who may  replace  any  absent  or  disqualified  member  at any  meeting  of the
committee.  Any such committee,  to the extent provided in the resolution of the
board,  shall have and may  exercise the powers of the board of directors in the
management of the business and affairs of the corporation, and may authorize the
seal of the corporation to be affixed to all papers which may require it. In the
absence or  disqualification  of any member of any such committee or committees,
the member or members thereof present at any meeting and not  disqualified  from
voting,  whether or not he or they constitute a quorum, may unanimously  appoint
another  member of the board of  directors to act at the meeting in the place of
any such absent or disqualified member.

         Section 7. ACTION IN WRITING.  Any action  required or  permitted to be
taken at any meeting of the board of directors or any  committee  thereof may be
taken without a meeting,  if all members of the board or committee,  as the case
may be, consent  thereto in writing,  and the writing or writings are filed with
the minutes of proceedings of the board or committee.

         Section 8.  COMPENSATION.  The board of  directors  may, by  resolution
passed by a majority of the whole board,  authorize  that the  directors be paid
their expenses,  if any, of attendance at each meeting of the board of directors
and be paid a fixed sum for attendance at each meeting of the board of directors
or a stated salary as director. No such payment shall preclude any director from
serving  the  corporation  in any  other  capacity  and  receiving  compensation
therefor.  Members  of  special  or  standing  committees  may be  allowed  like
compensation for attending committee meetings.


<PAGE>

         Section  9.  TRANSACTIONS  IN WHICH  DIRECTORS  MAY BE  INTERESTED.  No
contract or transaction between the corporation and one or more of its directors
or officers,  or between a corporation and any other  corporation,  partnership,
association  or other  organization  in which  one or more of its  directors  or
officers are directors or officers, or have a financial interest,  shall be void
or voidable solely for this reason, or solely because such directors or officers
are  present  at or  participate  in the  meeting  or  committee  thereof  which
authorizes the contract or transaction, or solely because his or their votes are
counted for such purpose;  provided  that the material  facts as to his or their
relationship  or interest and as to the contract or transaction are disclosed or
are known to the board of  directors  or the  committee,  or a majority  of such
members  thereof as shall be present at any meeting thereof at which action upon
any such contract or transaction  shall be taken,  and the board of directors or
committee in good faith authorizes the contract or transaction  without counting
the vote of the interested director or directors.  In any case described in this
Section 9 any interested director may be counted in determining the existence of
a quorum at any meeting of the board of directors or any  committee  which shall
authorize any such contract or transaction and may vote thereat to authorize any
such contract or transaction.  Any director of the corporation may vote upon any
contract or other  transaction  between the  corporation  and any  subsidiary or
affiliated  corporation without regard to the fact that he is also a director of
such subsidiary or affiliated corporation.

         Section 10. RATIFICATION OF DIRECTORS' ACTS. Any contract,  transaction
or act of the  corporation or of the board of directors  which shall be ratified
by a majority  of a quorum of the  stockholders  entitled  to vote at any annual
meeting or at any special  meeting called for that purpose shall be as valid and
binding as though ratified by every  stockholder of the  corporation;  provided,
however,  that any  failure  of the  stockholders  to  approve  or  ratify  such
contract,  transaction  or act when and if submitted to them shall not be deemed
in any way to invalidate the same or to deprive the  corporation,  its directors
or officers of their right to proceed with such contract, transaction or act.

                                   ARTICLE IV

                                    OFFICERS

         The directors shall elect a President and a Secretary, and may elect or
appoint such other officers and agents  (including a Chairman,  or more than one
Co-Chairmen, of the board of directors and/or a Chief Executive Officer, or more
than one Co-Chief Executive Officers) as are desired. The President may but need
not be a director. Any number of offices may be held by the same person.

         Unless otherwise provided in the resolution of election or appointment,
each  officer  shall hold  office  until the  meeting of the board of  directors
following the next annual  meeting of  stockholders  and until his successor has
been elected and qualified.

         Officers shall have the powers and duties  customarily  associated with
their office or as defined in the resolutions  appointing them;  provided,  that
the  Secretary  shall record all  proceedings  of the meetings or of the written
actions of the stockholders and of the directors,  and any committee thereof, in
a book to be kept for that purpose.

         The board of  directors  may  remove any  officer  for cause or without
cause. Any vacancy occurring in any office of the corporation shall be filled by
the board of directors.

                                    ARTICLE V

                         CERTIFICATES REPRESENTING STOCK


<PAGE>

         Section 1. CERTIFICATES  REPRESENTING STOCK. Certificates for shares of
the capital stock of the corporation  shall be in such form as shall be approved
by the directors.  They shall exhibit the holder's name and number of shares and
shall be  appropriately  numbered in the order of their  issue.  Every holder of
stock in the corporation  shall be entitled to have a certificate  signed by, or
in the name of, the  corporation by the President or a Vice President and by the
Treasurer or an Assistant  Treasurer or the Secretary or an Assistant  Secretary
of  the  corporation  certifying  the  number  of  shares  owned  by  him in the
corporation. If such certificate is countersigned by a transfer agent other than
the  corporation or its employee or by a registrar other than the corporation or
its employee, any other signature on the certificate may be a facsimile. In case
any  officer,  transfer  agent or  registrar  who has signed or whose  facsimile
signature  has been  placed  upon a  certificate  shall  have  ceased to be such
officer,  transfer  agent or  registrar  for any reason  whatsoever  before such
certificate is issued,  it may be issued by the corporation with the same effect
as if he were such  officer,  transfer  agent or registrar at the date of issue.
Whenever the  corporation  shall be  authorized  to issue more than one class of
stock  or more  than  one  series  of any  class  of  stock,  and  whenever  the
corporation  shall  issue any  shares of its stock as  partly  paid  stock,  the
certificates  representing  shares  of any such  class or  series or of any such
partly  paid stock  shall set forth  thereon the  statements  prescribed  by the
General  Corporation  Law. Any  restrictions  on the transfer or registration of
transfer  of any  shares  of  stock  of any  class  or  series  shall  be  noted
conspicuously on the certificate representing such shares.

         The  corporation  may issue a new  certificate of stock in place of any
certificate  theretofore  issued by it,  alleged to have been lost,  stolen,  or
destroyed, and the board of directors may require the owner of any lost, stolen,
or destroyed certificate, or his legal representative, to give the corporation a
bond sufficient to indemnify the corporation  against any claim that may be made
against it on account of the alleged loss,  theft,  or  destruction  of any such
certificate or the issuance of any such new certificate.

         Section 2. FRACTIONAL SHARE  INTERESTS.  The corporation may, but shall
not be required  to,  issue  fractions of a share of stock or it may pay in cash
the fair  value of  fractions  of a share  of  stock as of the time  when  those
entitled  to receive  such  fractions  are  determined  or it may issue scrip or
fractional  warrants in  registered  or bearer form over the manual or facsimile
signature of an officer of the  corporation  or of its agents,  exchangeable  as
therein provided for full shares of stock, but such scrip or fractional warrants
shall not entitle the holder to any rights of a stockholder  except as the board
of directors  shall  provide.  Such scrip or  fractional  warrants may be issued
subject to the  condition  that the same shall become void if not  exchanged for
certificates  representing  full  shares of stock  before a specified  date,  or
subject  to the  condition  that the  shares of stock for  which  such  scrip or
fractional  warrants are  exchangeable  may be sold by the  corporation  and the
proceeds  thereof  distributed  to the  holders  of  such  scrip  or  fractional
warrants,  or subject to any other  conditions  which the board of directors may
determine.

         Section  3.  STOCK  TRANSFERS.  Upon  compliance  with  the  provisions
restricting the transfer or registration of transfer of shares of stock, if any,
transfers or  registration  of  transfers of shares of stock of the  corporation
shall be made only on the  stock  ledger of the  corporation  by the  registered
holder  thereof,  or by his attorney  thereunto  authorized by power of attorney
duly executed and filed with the Secretary of the corporation or with a transfer
agent  or  a  registrar,  if  any,  and  on  surrender  of  the  certificate  or
certificates  for such shares of stock properly  endorsed and the payment of all
taxes due thereon.


<PAGE>


         Section 4. TRANSFER AGENT AND REGISTRAR.  The Corporation shall, if and
whenever  the  board of  directors  shall  so  determine,  maintain  one or more
transfer  offices or agencies,  each in charge of a transfer agent designated by
the board of directors  where the shares of the capital stock of the corporation
shall be directly transferable, and one or more registry offices, each in charge
of a registrar  designated by the board of directors  where such shares of stock
shall be registered,  and no certificate  for shares of the capital stock of the
corporation in respect of which a transfer  agent and registrar  shall have been
designated,  shall be valid  unless  countersigned  by such  transfer  agent and
registered  by such  registrar.  The  board  of  directors  may also  make  such
additional rules and regulations as it may deem expedient  concerning the issue,
transfer and registration of certificates for shares of the capital stock of the
corporation.

         Section 5. REGISTERED  STOCKHOLDERS.  The corporation shall be entitled
to treat the  holder of record of any share or shares of stock as the  holder in
fact thereof,  and accordingly  shall not be bound to recognize any equitable or
other  claim to or  interest  in such  share or  shares on the part of any other
person, whether or not it shall have express or other notice thereof,  except as
otherwise provided by the laws of Delaware.

                                   ARTICLE VI

                                    DIVIDENDS

         Section  1.  DIVIDENDS.   Dividends  upon  the  capital  stock  of  the
corporation,  subject to the provisions of the Certificate of Incorporation,  if
any,  may be  declared  by the board of  directors  at any  regular  or  special
meeting,  pursuant to law.  Dividends  may be paid in cash,  in property,  or in
shares of the capital  stock,  subject to the  provisions of the  Certificate of
Incorporation.

         Section 2. SPECIAL  PURPOSE  RESERVES.  Before payment of any dividend,
there  may be set  aside  out of any  funds  of the  corporation  available  for
dividends such sum or sums as the directors from time to time, in their absolute
discretion, think proper as a reserve or reserves to meet contingencies,  or for
equalizing  dividends,  or for  repairing  or  maintaining  any  property of the
corporation, or for such other purpose as the directors shall think conducive to
the interest of the  corporation,  and the  directors  may modify or abolish any
such reserve in the manner in which it was created.

                                   ARTICLE VII

                               GENERAL PROVISIONS

         Section 1.  CHECKS,  ETC.  All checks or demands for money and notes of
the corporation shall be signed by such officer or officers or such other person
or persons as the board of directors may from time to time designate.

         Section 2.  FISCAL YEAR.  The fiscal year of the corporation shall be
fixed, and shall be subject to change, by resolution of the board of directors.


<PAGE>


         Section  3.  VOTING  STOCK  IN  OTHER  CORPORATIONS.  Unless  otherwise
provided by resolution of the board of directors,  the Chairman of the Board, if
any, and if none, the President  may, from time to time,  appoint an attorney or
attorneys  or agent or agents of the  corporation,  in the name and on behalf of
the Corporation, to cast the votes which the corporation may be entitled to cast
as a stockholder  or otherwise in any other  corporation,  any of whose stock or
securities  may be held by the  corporation,  at  meetings of the holders of the
stock or other securities of such other corporation, or to consent in writing to
any action by any such other corporation, and may instruct the person or persons
so appointed as to the manner of casting such votes or giving such consent,  and
may execute or cause to be executed in the name and on behalf of the corporation
and under its seal or  otherwise,  such written  proxies,  consents,  waivers or
other  instruments  as such person or persons so appointed may deem necessary or
proper in the premises.

                                  ARTICLE VIII

                    INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Each   director,   officer  and  employee,   past  or  present  of  the
corporation, and each person who serves or may have served at the request of the
corporation as a director,  officer or employee of another corporation and their
respective  heirs,  administrators  and  executors,  shall be indemnified by the
corporation  in accordance  with,  and to the fullest  extent  permitted by, the
provisions  of the  General  Corporation  Law of the State of Delaware as it may
from time to time be amended.  Each agent of the corporation and each person who
serves  or may have  served at the  request  of the  corporation  as an agent of
another  corporation,  or as an  employee  or  agent of any  partnership,  joint
venture,  trust or other  enterprise  may,  in the  discretion  of the  board of
directors,  be  indemnified  by the  corporation  to the same extent as provided
herein with respect to directors, officers and employees of the corporation. The
provisions  of this  Article  VIII shall  apply to any  member of any  committee
appointed  by the board of  directors  as fully as though such person shall have
been an officer or director of the corporation.

         The board of directors may purchase and maintain insurance on behalf of
any  person  who  is or  was a  director,  officer,  employee  or  agent  of the
corporation,  or is or was  serving  at the  request  of  the  corporation  as a
director, officer, employee or agent of another corporation,  partnership, joint
venture,  trust or other enterprise  against any liability  asserted against him
and  incurred by him in any such  capacity or arising out of his status as such,
whether or not the  corporation  would have the power to  indemnify  him against
such liability  under the Certificate of  Incorporation,  By-Laws or the General
Corporation Law.

         The  provisions of this Article VIII shall be in addition to and not in
limitation  of any other rights,  indemnities,  or  limitations  of liability to
which any person may be entitled, as a matter of law or under the Certificate of
Incorporation, and By-Law, agreement, vote of stockholders or otherwise.

                                   ARTICLE IX

                             CONTROL OVER BY-LAWS

         If the Certificate of  Incorporation  so provides,  the power to adopt,
amend,  or repeal  By-Laws shall be vested in the board of directors;  provided,
that the board of directors may delegate such power, in whole or in part, to the
stockholders. If the Certificate of Incorporation does not so provide, the power
to make, alter, or repeal By-Laws shall be in the stockholders.



                                                                    Exhibit 10.1
                              SYMBOLLON CORPORATION
                             1993 STOCK OPTION PLAN

           1.       Purpose of the Plan.

           The purpose of the Symbollon  Corporation 1993 Stock Option Plan (the
"Plan")  is to  advance  the  interests  of  Symbollon  Corporation,  a Delaware
corporation  (the  "Company"),  by providing an opportunity for ownership of the
stock (or, in the case of SARs, as defined below,  the appreciation of the value
of the  stock) of the  Company  by  employees,  agents  and  directors  of,  and
consultants to, the Company and its subsidiaries, as defined below. By providing
such  opportunity,  the  Company  seeks to  attract  and retain  such  qualified
personnel, and otherwise to provide additional incentive for grantees to promote
the success of its business.

           2.       Stock Subject to the Plan.

           (a) The total  number of shares of the  authorized  but  unissued  or
treasury  shares of the class A common stock,  $.001 par value per share, of the
Company  (the  "Common  Stock")  for which  options  (the  "Options")  and stock
appreciation  rights  ("SARs")  may be granted  under the Plan shall be 400,000,
subject to adjustment as provided in Section 14 hereof.

           (b) If an  Option  granted  or  assumed  hereunder  shall  expire  or
terminate for any reason without having been exercised in full, the  unpurchased
shares  subject  thereto shall again be available for  subsequent  Option grants
under the Plan;  provided,  however,  that shares as to which an Option has been
surrendered  in connection  with the exercise of a related SAR will not again be
available for subsequent Option or SAR grants under the Plan.

           (c) Stock  issuable upon exercise of an Option may be subject to such
restrictions on transfer,  repurchase  rights or other  restrictions as shall be
determined by the Board of Directors of the Company (the "Board").

           3.       Administration of the Plan.

           (a) The Plan shall be  administered  by the  Board.  No member of the
Board shall act upon any matter exclusively  affecting any Option or SAR granted
or to be granted to himself or herself under the Plan. A majority of the members
of the  Board  shall  constitute  a  quorum,  and any  action  may be taken by a
majority of those  present and voting at any meeting.  The decision of the Board
as to all  questions  of  interpretation  and  application  of the Plan shall be

<PAGE>

final, binding and conclusive on all persons. The Board, in its sole discretion,
may grant  Options to purchase  shares of Common  Stock and may grant  SARs,  as
provided  in the Plan.  The Board shall have  authority,  subject to the express
provisions of the Plan, to construe the respective Option and SAR agreements and
the Plan, to prescribe,  amend and rescind rules and regulations relating to the
Plan, to determine the terms and  provisions  of the  respective  Option and SAR
agreements,  which  may  but  need  not be  identical,  and to  make  all  other
determinations  in the  judgment of the Board  necessary  or  desirable  for the
administration  of the Plan.  The Board may  correct  any  defect or supply  any
omission  or  reconcile  any  inconsistency  in the Plan or in any Option or SAR
agreement  in the manner and to the extent it shall deem  expedient to implement
the Plan and shall be the sole and final judge of such  expediency.  No director
shall be liable for any action or  determination  made in good faith. The Board,
in its  discretion,  may delegate its power,  duties and  responsibilities  to a
committee,  consisting of two or more members of the Board,  all of whom must be
"non-employee"  directors  (as defined  under Rule 16b-3  promulgated  under the
Securities  Exchange Act of 1934, as amended (the "Exchange Act")), as such term
is interpreted  from time to  time.hereinafter.  If a committee is so appointed,
all  references  to the Board  herein  shall mean and relate to such  committee,
unless the context otherwise requires.

           4.       Type of Options.

           Options granted pursuant to the Plan shall be authorized by action of
the Board and may be designated as either  incentive  stock options  meeting the
requirements  of Section 422 of the Internal  Revenue  Code of 1986,  as amended
(the  "Code"),  or  non-qualified  options  which are not  intended  to meet the
requirements  of such Section 422 of the Code, the designation to be in the sole
discretion of the Board. Options designated as incentive stock options that fail
to  continue  to meet the  requirements  of  Section  422 of the  Code  shall be
redesignated as non-qualified  options  automatically  without further action by
the Board on the date of such  failure to continue to meet the  requirements  of
Section 422 of the Code.

           5.       Eligibility.

           Options  designated as incentive stock options may be granted only to
officers  and key  employees  of the  Company or of any  subsidiary  corporation
(herein called "subsidiary" or "subsidiaries"),  as defined in Section 424(f) of
the  Code  and  the  Treasury   regulations  (the   "Regulations")   promulgated
thereunder.  Directors  who are not  otherwise  employees  of the  Company  or a
subsidiary shall not be eligible to be granted  incentive stock options pursuant
to the Plan. Options  designated as non-qualified  options may be granted to (i)
officers and key employees of the Company or of any of its subsidiaries, or (ii)
agents,  directors of and  consultants to the Company,  whether or not otherwise
employees of the Company.


<PAGE>

           In  determining  the  eligibility  of an  individual to be granted an
Option or SAR, as well as in  determining  the number of shares to be subject to
any such Option or SAR,  the Board  shall take into  account  the  position  and
responsibilities of the individual being considered, the nature and value to the
Company or its  subsidiaries of his or her service and  accomplishments,  his or
her  present  and  potential  contribution  to the success of the Company or its
subsidiaries, and such other factors as the Board may deem relevant.

           6.       Restrictions on Incentive Stock Options.

           Incentive stock options (but not non-qualified options) granted under
this Plan shall be subject to the following restrictions:

           (a)  Limitation on Number of Shares.  Ordinarily,  the aggregate fair
           market  value of the  shares of Common  Stock  with  respect to which
           incentive  stock options are granted  (determined  as of the date the
           incentive stock options are granted),  exercisable for the first time
           by an individual  during any calendar year shall not exceed $100,000.
           If an  incentive  stock  option  is  granted  pursuant  to which  the
           aggregate  fair market value of shares with respect to which it first
           becomes  exercisable  in any calendar year by an  individual  exceeds
           such  $100,000  limitation,  the portion of such  option  which is in
           excess of the $100,000 limitation shall be treated as a non-qualified
           option  pursuant to Section  422(d)(1) of the Code. In the event that
           an  individual is eligible to  participate  in any other stock option
           plan of the Company or any  subsidiary  of the Company  which is also
           intended  to comply with the  provisions  of Section 422 of the Code,
           such  $100,000  limitation  shall  apply to the  aggregate  number of
           shares for which  incentive  stock  options may be granted under this
           Plan and all such other plans.

           (b)  Ten  Percent  (10%)  Shareholder.  If any  employee  to  whom an
           incentive stock option is granted  pursuant to the provisions of this
           Plan is on the date of grant the owner of stock (as determined  under
           Section  424(d)  of the Code)  possessing  more than 10% of the total
           combined  voting  power of all classes of stock of the Company or any
           subsidiary  of the Company,  then the  following  special  provisions
           shall be applicable to the  incentive  stock options  granted to such
           individual:

                    (i)      The  Option   price  per  share   subject  to  such
                             incentive stock options shall be not less than 110%
                             of the fair market value of the stock determined at
                             the time such Option was  granted.  In  determining
                             the fair market  value  under this clause (i),  the
                             provisions of Section 8 hereof shall apply.

                    (ii)     The  incentive  stock option by its terms shall not
                             be  exercisable  after the  expiration  of five (5)
                             years from the date such Option is granted.


<PAGE>

           7.       Option and SAR Agreements.

           Each  Option  and  SAR  shall  be  evidenced  by  an  agreement  (the
"Agreement")  duly  executed on behalf of the Company and by the grantee to whom
such Option or SAR is granted,  which Agreement shall comply with and be subject
to the terms and  conditions  of the Plan.  The Agreement may contain such other
terms, provisions and conditions which are not inconsistent with the Plan as may
be determined by the Board;  provided that Options designated as incentive stock
options shall meet all of the conditions for incentive  stock options as defined
in Section 422 of the Code. No Option or SAR shall be granted within the meaning
of the Plan and no purported grant of any Option or SAR shall be effective until
the  Agreement  shall have been duly  executed  on behalf of the Company and the
grantee. More than one Option and SAR may be granted to an individual,  subject,
if applicable, to the limitations of Section 6.

           8.       Option Price.

           (a) The  Option  price or prices of  shares of the  Common  Stock for
Options designated as non-qualified  stock options shall be as determined by the
Board;  provided,  however, that such Option price shall be not less than 85% of
the fair market value of the shares subject to such Option, determined as of the
date of grant of such Option.

           (b) Subject to the conditions  set forth in Section 6(b) hereof,  the
Option price or prices of shares of the  Company's  Common  Stock for  incentive
stock  options  shall be at least the fair market  value of such Common Stock at
the time the Option is granted as determined by the Board in accordance with the
Regulations promulgated under Section 422 of the Code.

           (c) If  such  shares  are  then  listed  on any  national  securities
exchange, the fair market value shall be the mean between the high and low sales
prices,  if any,  on the largest  such  exchange on the date of the grant of the
Option or, if none,  shall be  determined  by taking a  weighted  average of the
means between the highest and lowest sales prices on the nearest date before and
the nearest date after the date of grant in accordance with Section 25.2512-2 of
the  Regulations.  If the shares are not then listed on any such  exchange,  the
fair market value of such shares shall be the mean between the closing "Bid" and
the closing "Ask"  prices,  if any, as reported in the National  Association  of
Securities  Dealers  Automated  Quotation System  ("NASDAQ") for the date of the
grant of the  Option,  or, if none,  shall be  determined  by taking a  weighted
average of the means  between the highest and lowest sales prices on the nearest
date  before and the  nearest  date after the date of grant in  accordance  with
Section  25.2512-2 of the Regulations.  If the shares are not then either listed
on any such  exchange or quoted in NASDAQ,  the fair  market  value shall be the
mean between the average of the "Bid" National Daily  Quotation  Service for the
date of the grant of the Option,  or, if none,  shall be  determined by taking a
weighted average of the means between the highest and lowest sales prices on the
nearest date before and the nearest  date after the date of grant in  accordance
with Section  25.2512-2 of the  Regulations.  If the fair market value cannot be
determined under the preceding three  sentences,  it shall be determined in good
faith by the Board.

           9.       Manner of Payment; Manner of Exercise.

           (a) Options granted under the Plan may provide for the payment of the
exercise  price by delivery  of (i) cash or a check  payable to the order of the
Company in an amount equal to the exercise price of such Options, (ii) shares of
Common Stock owned by the grantee  having a fair market value equal in amount to
the exercise price of the Options being  exercised,  or (iii) any combination of
(i) and (ii); provided,  however, that payment of the exercise price by delivery
of  shares  of  Common  Stock  owned by such  grantee  may be made only upon the
condition  that  such  payment  does not  result  in a charge  to  earnings  for
financial  accounting purposes as determined by the Board, unless such condition
is waived by the Board.  The fair  market  value of any  shares of Common  Stock
which may be delivered  upon  exercise of an Option shall be  determined  by the
Board in accordance with Section 8 hereof.


<PAGE>

           (b) To the extent that the right to purchase  shares  under an Option
has accrued and is in effect, Options may be exercised in full at one time or in
part  from time to time,  by  giving  written  notice,  signed by the  person or
persons exercising the Option, to the Company, stating the number of shares with
respect to which the Option is being  exercised,  accompanied by payment in full
for such shares as  provided  in  subparagraph  (a) above.  Upon such  exercise,
delivery of a certificate for paid-up non-assessable shares shall be made at the
principal  office of the Company to the person or persons  exercising the Option
at such time,  during ordinary  business  hours,  after thirty (30) days but not
more  than  ninety  (90)  days  from the date of  receipt  of the  notice by the
Company,  as shall be  designated  in such  notice,  or at such time,  place and
manner as may be agreed upon by the Company and the person or persons exercising
the Option.

           10.      Exercise of Options and SARs.

           Each Option and SAR granted under the Plan shall,  subject to Section
11(b) and  Section 14 hereof,  be  exercisable  at such time or times and during
such period as shall be set forth in the Agreement;  provided,  however, that no
Option or SAR  granted  under the Plan  shall  have a term in excess of ten (10)
years  from  the date of  grant.  To the  extent  that an  Option  or SAR is not
exercised  by a grantee  when it  becomes  initially  exercisable,  it shall not
expire but shall be carried  forward and shall be  exercisable,  on a cumulative
basis,  until the expiration of the exercise period.  No partial exercise may be
made for less than one hundred (100) full shares of Common  Stock.  The exercise
of an Option shall result in the cancellation of any related SAR with respect to
the same number of shares of Common Stock as to which the Option was exercised.

           11.      Term of Options and SARs; Exercisability.

           (a)      Term.

                    (i)         Each  Option  and  SAR  shall  expire  on a date
                                determined  by the Board  which is not more than
                                ten (10)  years  from  the date of the  granting
                                thereof,   except  (a)  as  otherwise   provided
                                pursuant  to  the  provisions  of  Section  6(b)
                                hereof,  and  (b)  for  earlier  termination  as
                                herein provided.

                    (ii)        Except as otherwise provided in this Section 11,
                                an Option or SAR  granted to any  grantee  whose
                                employment,  for  the  Company  or  any  of  its
                                subsidiaries,  is terminated, shall terminate on
                                the  earlier of (i)  ninety  days after the date
                                such  grantee's  employment,  for the Company or
                                any such subsidiary,  is terminated, or (ii) the
                                date on which the  Option or SAR  expires by its
                                terms.

                    (iii)       If the  employment of a grantee is terminated by
                                the Company or any of its subsidiaries for cause
                                or  because  the  grantee  is in  breach  of any
                                employment  agreement,  such  Option or SAR will
                                terminate on the date the  grantee's  employment
                                is   terminated  by  the  Company  or  any  such
                                subsidiary.


<PAGE>

                    (iv)        If the  employment of a grantee is terminated by
                                the Company or any of its  subsidiaries  because
                                the  grantee  has  become  permanently  disabled
                                (within the  meaning of Section  22(e)(3) of the
                                Code), such Option or SAR shall terminate on the
                                earlier  of (i) one year  after  the  date  such
                                grantee's  employment,  for the  Company  or any
                                such subsidiary, is terminated, or (ii) the date
                                on which the Option or SAR expires by its terms.

                    (v)         In the  event of the death of any  grantee,  any
                                Option  or SAR  granted  to such  grantee  shall
                                terminate  one year after the date of death,  or
                                on the date on which the  Option or SAR  expires
                                by its terms, whichever occurs first.

           (b)      Exercisability.

                    (i)         Except  as  provided  below,  an  Option  or SAR
                                granted to a grantee whose  employment,  for the
                                Company   or  any  of   its   subsidiaries,   is
                                terminated,  shall  be  exercisable  only to the
                                extent  that such  Option or SAR has accrued and
                                is  in  effect   on  the  date  such   grantee's
                                employment,   for  the   Company   or  any  such
                                subsidiary, is terminated.

                    (ii)        An Option  or SAR  granted  to a  grantee  whose
                                employment  is  terminated by the Company or any
                                of its subsidiaries because he or she has become
                                permanently disabled, as defined above, shall be
                                immediately exercisable as to the full number of
                                shares covered by such Option or SAR, whether or
                                not under the  provisions  of  Section 10 hereof
                                such Option or SAR was otherwise  exercisable as
                                of the date of disability.

                    (iii)       In the  event  of the  death of a  grantee,  the
                                Option or SAR  granted  to such  grantee  may be
                                exercised  as  to  the  full  number  of  shares
                                covered  thereby,   whether  or  not  under  the
                                provisions  of Section 10 hereof the grantee was
                                entitled  to do so at  the  date  of  his or her
                                death,   by  the  executor,   administrator   or
                                personal  representative of such grantee,  or by
                                any person or persons who  acquired the right to
                                exercise  such  Option  or  SAR  by  bequest  or
                                inheritance  or by  reason  of the death of such
                                grantee.

                    (iv)        Neither an SAR nor an Option granted  granted in
                                connection  with an SAR to a person  subject  to
                                Section   16(b)  of  the  Exchange  Act  may  be
                                exercised  before six  months  after the date of
                                grant.



<PAGE>

           12.      Options and SARs Not Transferable.

           The right of any grantee to exercise any Option or SAR granted to him
or her shall not be  assignable  or  transferable  by such grantee other than by
will or the laws of descent and distribution or pursuant to a domestic relations
order  as  defined  in the  Code or Title 1 of the  Employee  Retirement  Income
Security  Act,  or the  rules  thereunder,  and any such  Option or SAR shall be
exercisable  during the  lifetime of such grantee only by him or her. Any Option
or SAR granted under the Plan shall be null and void and without effect upon the
bankruptcy  of the  grantee  to whom the Option or SAR is  granted,  or upon any
attempted assignment or transfer,  except as herein provided,  including without
limitation, any purported assignment,  whether voluntary or by operation of law,
pledge,  hypothecation  or other  disposition,  attachment,  trustee  process or
similar process, whether legal or equitable, upon such Option or SAR.

           13. Terms and Conditions of SARs.

           (a) An SAR may be granted  separately or in connection with an Option
(either at the time of grant or at any time during the term of the Option).

           (b) The  exercise of an SAR shall result in the  cancellation  of the
Option to which it relates  with  respect to the same number of shares of Common
Stock as to which the SAR was exercised.

           (c) An SAR granted in connection  with an Option shall be exercisable
or  transferable  only to the extent that such related  Option is exercisable or
transferable.

           (d) Upon the exercise of an SAR related to an Option, the holder will
be entitled to receive payment of an amount determined by multiplying:

                    (i) The  difference  obtained by  subtracting  the  purchase
price of a share of Common Stock  specified in the related  Option from the fair
market  value of a share of Common Stock on the date of exercise of such SAR (as
determined by the Board), by

                    (ii) The number of shares as to which such SAR is exercised.

           (e) An  SAR  granted  without  relationship  to an  Option  shall  be
exercisable as determined by the Board, but in no event after ten years from the
date of grant.

           (f) An SAR granted without relationship to an Option will entitle the
holder,  upon exercise of the SAR, to receive payment of an amount determined by
multiplying:

                    (i) The difference  obtained by subtracting  the fair market
value of the a share of Common  Stock on the date the SAR was  granted  from the
fair market value of a share of Common Stock on the date of exercise of such SAR
(as determined by the Board), by

                    (ii) The number of shares as to which such SAR is exercised.

           (g)  Notwithstanding  subsections  (d) and (f)  above,  the Board may
limit the amount payable upon exercise of an SAR. Any such  limitation  shall be
determined as of the date of grant and noted on the  instrument  evidencing  the
SAR granted.

           (h) At the discretion of the Board,  payment of the amount determined
under subsections (d) and (f) above may be made solely in whole shares of Common
Stock  valued at their fair market  value on the date of exercise of the SAR (as
determined by the Board),  or solely in cash,  or in a  combination  of cash and
shares.  If the Board decides to make full payment in shares of Common Stock and
the amount  payable  results in a fractional  share,  payment for the fractional
share shall be made in cash.


<PAGE>

           14.      Recapitalization, Reorganizations and the Like.

           In the event  that the  outstanding  shares of the  Common  Stock are
changed  into or  exchanged  for a  different  number or kind of shares or other
securities  of  the  Company  or  of  another   corporation  by  reason  of  any
reorganization, merger, consolidation, recapitalization, reclassification, stock
split-up,  combination  of  shares,  or  dividends  payable  in  capital  stock,
appropriate  adjustment  shall be made in the  number  and kind of  shares as to
which Options and SARs may be granted under the Plan and as to which outstanding
Options,  SARs, or portions thereof then unexercised,  shall be exercisable,  to
the end that the  proportionate  interest of the grantee  shall be maintained as
before the occurrence of such event; such adjustment in outstanding  Options and
SARs  shall  be  made  without  change  in the  total  price  applicable  to the
unexercised portion of such Options and SARs and with a corresponding adjustment
in the Option price per share.

           In addition,  unless  otherwise  determined  by the Board in its sole
discretion,  in the case of any (i) sale or conveyance to another  entity of all
or substantially all of the property and assets of the Company or (ii) Change in
Control  (as  hereinafter  defined)  of the  Company,  the  purchaser(s)  of the
Company's  assets or stock, in his, her or its sole  discretion,  may deliver to
the grantee the same kind of consideration that is delivered to the shareholders
of the Company as a result of such sale, conveyance or Change in Control, or the
Board may cancel all outstanding  Options in exchange for  consideration in cash
or in kind,  which  consideration  in both cases  shall be equal in value to the
value of those  shares  of stock or other  securities  the  grantee  would  have
received had the Option been exercised (but only to the extent then exercisable)
and had no disposition of the shares acquired upon such exercise been made prior
to such sale,  conveyance or Change in Control,  less the Option price therefor.
Upon  receipt  of  such   consideration,   all  Options  (whether  or  not  then
exercisable)  shall immediately  terminate and be of no further force or effect.
The value of the stock or other  securities  the grantee  would have received if
the Option had been  exercised  shall be  determined in good faith by the Board,
and in the case of shares of Common Stock,  in accordance with the provisions of
Section 8 hereof.

           The Board  shall  also have the  power  and right to  accelerate  the
exercisability of any Options,  notwithstanding  any limitations in this Plan or
in the Agreement  upon such a sale,  conveyance or Change in Control.  Upon such
acceleration,  any Options or portion thereof originally designated as incentive
stock  options that no longer  qualify as incentive  stock options under Section
422 of the Code as a  result  of such  acceleration  shall  be  redesignated  as
non-qualified stock options without the necessity of further Board action.

           A "Change in Control" shall be deemed to have occurred if any person,
or any two or more persons acting as a group,  and all affiliates of such person
or persons,  who prior to such time owned less than fifty  percent  (50%) of the
then outstanding  Common Stock,  shall acquire such additional  shares of Common
Stock  in one or  more  transactions,  or  series  of  transactions,  such  that
following such transaction or transactions,  such person or group and affiliates
beneficially own fifty percent (50%) or more of the Common Stock outstanding.

           Upon dissolution or liquidation of the Company,  all Options and SARs
granted  under this Plan shall  terminate,  but each grantee (if at such time in
the  employ  of  or  otherwise  associated  with  the  Company  or  any  of  its
subsidiaries  as  a  director,  agent  or  consultant)  shall  have  the  right,
immediately  prior to such  dissolution or  liquidation,  to exercise his or her
Option or SAR to the extent then exercisable.


<PAGE>

           If by reason of a corporate  merger,  consolidation,  acquisition  of
property or stock, separation,  reorganization,  or liquidation, the Board shall
authorize  the issuance or  assumption  of a stock option or stock  options in a
transaction to which Section 424(a) of the Code applies,  then,  notwithstanding
any other  provision of the Plan,  the Board may grant an option or options upon
such  terms  and  conditions  as it may  deem  appropriate  for the  purpose  of
assumption  of the old  Option,  or  substitution  of a new  option  for the old
Option, in conformity with the provisions of such Section 424(a) of the Code and
the  Regulations  thereunder,  and any such  option  grant  shall not reduce the
number of shares otherwise available for issuance under the Plan.

           No fraction of a share shall be purchasable  or deliverable  upon the
exercise of any Option, but in the event any adjustment  hereunder in the number
of shares covered by the Option shall cause such number to include a fraction of
a share,  such fraction shall be adjusted to the nearest smaller whole number of
shares.

           15.      No Special Employment Rights.

           Nothing  contained in the Plan or in any Option or SAR granted  under
the  Plan  shall  confer  upon  any  grantee  any  right  with  respect  to  the
continuation  of his or her  employment  by the  Company  or any  subsidiary  or
interfere in any way with the right of the Company or any subsidiary, subject to
the terms of any separate employment  agreement to the contrary,  at any time to
terminate  such  employment or to increase or decrease the  compensation  of the
Option or SAR holder from the rate in  existence  at the time of the grant of an
Option or SAR. Whether an authorized leave of absence, or absence in military or
government  service,   shall  constitute  termination  of  employment  shall  be
determined  by the  Board at the time of such  occurrence  pursuant  to  uniform
nondiscriminatory criteria.

           16.      Withholding.

           The Company's  obligation to deliver  shares upon the exercise of any
non-qualified Option granted under the Plan, or cash upon the exercise of an SAR
granted under the Plan,  shall be subject to the grantee's  satisfaction  of all
applicable  Federal,  state and local  income  and  employment  tax  withholding
requirements.  The Company  and  grantee may agree to withhold  shares of Common
Stock  purchased  upon  exercise  of an Option to  satisfy  the  above-mentioned
withholding requirements;  provided, however, no such agreement may be made by a
grantee who is an  "officer" or  "director"  within the meaning of Section 16 of
the Exchange Act, except  pursuant to a standing  election to so withhold shares
of Common Stock  purchased upon exercise of an Option,  such election to be made
not less  than six  months  prior to such  exercise  and which  election  may be
revoked only upon six months prior written notice.

           17.      Restrictions on Issuance of Shares.

           (a)  Notwithstanding  the  provisions  of Section 9, the  Company may
delay the  issuance  of shares  covered  by the  exercise  of an Option  and the
delivery of a certificate for such shares until one of the following  conditions
shall be satisfied:


<PAGE>

                    (i)         The shares with respect to which such Option has
                                been  exercised  are at the time of the issue of
                                such shares effectively  registered or qualified
                                under  applicable  Federal and state  securities
                                acts now in force or as hereafter amended; or

                    (ii)        Counsel  for the  Company  shall  have  given an
                                opinion, which opinion shall not be unreasonably
                                conditioned  or  withheld,  that such shares are
                                exempt from registration and qualification under
                                applicable Federal and state securities acts now
                                in force or as hereafter amended.

           (b) It is intended  that all exercises of Options shall be effective,
and the Company  shall use its best efforts to bring about  compliance  with the
above  conditions  within a reasonable  time,  except that the Company  shall be
under no obligation to qualify shares or to cause a registration  statement or a
post-effective  amendment to any  registration  statement to be prepared for the
purpose  of  covering  the issue of shares in respect of which any Option may be
exercised,  except as otherwise  agreed to by the Company in writing in its sole
discretion.

           18.      Purchase for Investment; Rights of Holder on Subsequent
                    Registration.

           Unless and until the shares to be issued  upon  exercise of an Option
granted under the Plan have been effectively registered under the Securities Act
of 1933, as amended (the "1933 Act"), as now in force or hereafter amended,  the
Company shall be under no  obligation to issue any shares  covered by any Option
unless the person who exercises such Option,  in whole or in part,  shall give a
written  representation  and undertaking to the Company which is satisfactory in
form and scope to counsel for the Company and upon which, in the opinion of such
counsel, the Company may reasonably rely, that he or she is acquiring the shares
issued  pursuant to such exercise of the Option for his or her own account as an
investment  and  not  with a view  to,  or for  sale  in  connection  with,  the
distribution of any such shares, and that he or she will make no transfer of the
same except in compliance with any rules and regulations in force at the time of
such  transfer  under the 1933 Act,  or any other  applicable  law,  and that if
shares are issued  without  such  registration,  a legend to this  effect may be
endorsed upon the securities so issued.

           In the event that the Company shall, nevertheless,  deem it necessary
or desirable  to register  under the 1933 Act or other  applicable  statutes any
shares with respect to which an Option shall have been exercised,  or to qualify
any such shares for exemption  from the 1933 Act or other  applicable  statutes,
then the Company may take such action and may  require  from each  grantee  such
information  in writing  for use in any  registration  statement,  supplementary
registration statement, prospectus,  preliminary prospectus or offering circular
as is reasonably necessary for such purpose and may require reasonable indemnity
to the Company  and its  officers  and  directors  from such holder  against all
losses, claims, damages and liabilities arising from such use of the information
so furnished and caused by any untrue  statement of any material fact therein or
caused by the omission to state a material fact required to be stated therein or
necessary  to make the  statements  therein not  misleading  in the light of the
circumstances under which they were made.


<PAGE>

           19.      Loans.

           At the  discretion of the Board,  the Company may loan to the grantee
some or all of the purchase  price of the shares  acquired  upon  exercise of an
Option.

           20.      Modification of Outstanding Options and SARs.

           Subject to any applicable limitations contained herein, the Board may
authorize the amendment of any outstanding Option or SAR with the consent of the
grantee  when and  subject  to such  conditions  as are deemed to be in the best
interests of the Company and in accordance with the purposes of the Plan.

           21.      Approval of Stockholders.

           The Plan shall become effective upon adoption by the Board; provided,
however,  that the Plan shall be submitted for approval by the  stockholders  of
the Company no later than  twelve (12) months  after the date of adoption of the
Plan by the Board.  Should the  stockholders  of the Company fail to approve the
Plan within such twelve-month  period,  all Options granted  thereunder shall be
and become null and void.

           22.      Termination and Amendment of Plan.

           Unless sooner terminated as herein provided, the Plan shall terminate
ten (10) years  from the date upon which the Plan was duly  adopted by the Board
of the  Company.  The  Board  may at any time  terminate  the Plan or make  such
modification or amendment thereof as it deems advisable;  provided, however, (i)
the Board may not,  without  the  approval  of the  stockholders  of the Company
obtained in the manner  stated in Section  21,  increase  the maximum  number of
shares for which  Options and SARs may be granted or change the  designation  of
the class of persons  eligible to receive  Options and SARs under the Plan,  and
(ii) any such  modification  or  amendment  of the Plan shall be  approved  by a
majority of the  stockholders of the Company to the extent that such stockholder
approval is necessary to comply with  applicable  provisions of the Code,  rules
promulgated pursuant to Section 16 of the Exchange Act, applicable state law, or
applicable   NASD  or  exchange   listing   requirements.   Termination  or  any
modification  or  amendment  of the Plan shall  not,  without  the  consent of a
grantee,  affect his or her rights under an Option or SAR theretofore granted to
him or her.

           23.      Limitation of Rights in the Option Shares.

           A grantee shall not be deemed for any purpose to be a stockholder  of
the Company  with  respect to any of the  Options  except to the extent that the
Option  shall have been  exercised  with respect  thereto  and, in  addition,  a
certificate shall have been issued theretofore and delivered to the grantee.

           24.      Notices.

           Any  communication  or notice required or permitted to be given under
the Plan shall be in writing,  and mailed by  registered  or  certified  mail or
delivered by hand,  if to the Company,  to the attention of the President at the
Company's  principal  place of  business;  and,  if to a grantee,  to his or her
address as it appears on the records of the Company.


<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
CONDENSED UNAUDITED FINANCIAL STATEMENT OF SYMBOLLON CORPORATION FOR THE SIX
MONTHS ENDED JUNE 30, 1999 AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE
TO SUCH FINANCIAL STATEMENT AS FILED IN THE FORM 10-QSB.
</LEGEND>
<MULTIPLIER>                                  1

<S>                             <C>
<PERIOD-TYPE>                   6-MOS
<FISCAL-YEAR-END>                              DEC-31-1999
<PERIOD-START>                                 JAN-01-1999
<PERIOD-END>                                   JUN-30-1999
<CASH>                                         1,202,538
<SECURITIES>                                           0
<RECEIVABLES>                                     76,248
<ALLOWANCES>                                           0
<INVENTORY>                                       81,161
<CURRENT-ASSETS>                               1,688,976
<PP&E>                                           286,134
<DEPRECIATION>                                   177,144
<TOTAL-ASSETS>                                 2,013,785
<CURRENT-LIABILITIES>                            476,687
<BONDS>                                                0
                            350,000
                                            0
<COMMON>                                           3,420
<OTHER-SE>                                     1,187,098
<TOTAL-LIABILITY-AND-EQUITY>                   2,013,785
<SALES>                                          172,500
<TOTAL-REVENUES>                                 361,379
<CGS>                                            140,190
<TOTAL-COSTS>                                          0
<OTHER-EXPENSES>                                 914,108
<LOSS-PROVISION>                                       0
<INTEREST-EXPENSE>                                     0
<INCOME-PRETAX>                                 (858,435)
<INCOME-TAX>                                           0
<INCOME-CONTINUING>                             (858,435)
<DISCONTINUED>                                         0
<EXTRAORDINARY>                                        0
<CHANGES>                                              0
<NET-INCOME>                                    (858,435)
<EPS-BASIC>                                       (.30)
<EPS-DILUTED>                                       (.30)




</TABLE>


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