CUBIST PHARMACEUTICALS INC
8-A12G, 1996-09-17
PHARMACEUTICAL PREPARATIONS
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<PAGE>
 
                      SECURITIES AND EXCHANGE COMMISSION

                            WASHINGTON, D.C.  20549

                                 _____________

                                    FORM 8-A

               FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES
                   PURSUANT TO SECTION 12(B) OR 12(G) OF THE
                        SECURITIES EXCHANGE ACT OF 1934

                          CUBIST PHARMACEUTICALS, INC.
                          ----------------------------
             (Exact Name of Registrant as Specified in its Charter)



        DELAWARE                                                      22-3192085
- --------------------------------------------------------------------------------
(State of Incorporation or Organization)                        (I.R.S. Employer
                                                             Identification no.)

24 Emily Street, Cambridge, Massachusetts                                  02139
- --------------------------------------------------------------------------------
(Address of principal executive offices)                              (zip code)

   If this Form relates to the                If this Form relates to the
   registration of a class of debt            registration of a class of debt
   securities and is effective upon filing    securities and is to become
   pursuant to General                        simultaneously with the
   Instruction A(c)(1) please check           effectiveness of a concurrent
   the following box. / /                     registration statement under the
                                              Securities Act of 1933 pursuant to
                                              General Instruction A(c)(2) please
                                              check the following box. / /

Securities to be registered pursuant to Section 12(b) of the Act:

Title of Each Class                 Name of Each Exchange on Which
to be so Registered                  Each Class is to be Registered
- -------------------                 --------------------------------
                         None.

Securities to be registered pursuant to Section 12(g) of the Act:

                        Common Stock, $0.001 par value
- --------------------------------------------------------------------------------
                               (Title of Class)
<PAGE>
 
                INFORMATION REQUIRED IN REGISTRATION STATEMENT



ITEM 1.  DESCRIPTION OF REGISTRANT'S SECURITIES TO BE REGISTERED

     The information required by Item 202 of Regulation S-K is included under
the heading "Description of Capital Stock" in the Registrant's Registration
Statement on Form S-1, filed with the Securities and Exchange Commission on June
25, 1996 (the "Registration Statement"), including any form of the prospectus
contained therein filed by the Registrant pursuant to Rule 424(b) under the
Securities Act of 1933, as amended, which is incorporated herein by reference.

ITEM 2.  EXHIBITS

     1.   The Restated Certificate of Incorporation of the Registrant is
incorporated herein by reference to Exhibit 3.1 to the Registration Statement.

     2.   The Amended and Restated By-Laws of the Registrant are incorporated
herein by reference to Exhibit 3.4 to the Registration Statement.

     3.   A specimen copy of the certificate representing shares of the
Registrant's Common Stock is incorporated herein by reference to Exhibit 4.1 to
the Registration Statement.
<PAGE>
 
                                   SIGNATURE


     Pursuant to the Requirements of Section 12 of the Securities Exchange Act
of 1934, the registrant has duly caused this registration statement to be signed
on its behalf by the undersigned, thereto duly authorized.


                                 CUBIST PHARMACEUTICALS, INC.



                                 By: /s/ Scott M. Rocklage
                                 ----------------------------------
                                     Name:  Scott M. Rocklage
                                     Title: President and
                                            Chief Executive Officer


Date: September 17, 1996


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