<PAGE>
Prospectus Supplement Filed Pursuant to Rule 424(b)(3)
(To Prospectus dated December 7, 2000) Registration No. 333-49284
3,463,651 Shares
VITAL IMAGES, INC.
Common Stock
This prospectus supplement contains information about the persons who
can use this prospectus supplement to offer and sell common stock of Vital
Images, Inc. that those persons own.
SELLING SHAREHOLDERS
The information set forth in the table under the caption "Selling
Shareholders" in the Vital Images, Inc. prospectus dated December 7, 2000
relating to the ownership of common stock of Vital Images, Inc. is supplemented
to amend, as follows, the information contained therein regarding the following
shareholder:
<TABLE>
<CAPTION>
Shares Beneficially Shares Beneficially
Owned Prior Shares Owned After
to Offering (1) to be Sold Offering
-------------------------------------------------- ---------- ----------------------
Shares Total
Underlying Number of
Beneficial Owner Shares(2) Warrants Shares Percent(3) Number Percent (3)
---------------- --------- -------- ------ ---------- ------ -----------
<S> <C> <C> <C> <C> <C> <C> <C>
Dain Rauscher Custodian FBO 13,000 6,000 19,000 * 12,000 7,000 *
Sheldon Chester IRA
</TABLE>
The Footnotes to this Table are set forth in the Prospectus dated December 7,
2000.
The date of this prospectus is December 14, 2000.
