ARRIS PHARMACEUTICAL CORP/DE/
S-8, 1996-07-29
PHARMACEUTICAL PREPARATIONS
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<PAGE>
AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JULY 29, 1996
                                                           REGISTRATION NO. 333-

                          SECURITIES AND EXCHANGE COMMISSION
                                Washington, D.C. 20549

                         ------------------------------
                                       FORM S-8
                                REGISTRATION STATEMENT
                                        UNDER
                              THE SECURITIES ACT OF 1933

                         ------------------------------
                           ARRIS PHARMACEUTICAL CORPORATION
                (Exact name of registrant as specified in its charter)

                         ------------------------------
            DELAWARE                                22-2969941
    (State of Incorporation)           (I.R.S. Employer Identification No.)

                         ------------------------------
                         385 OYSTER POINT BOULEVARD, SUITE 3
                        SOUTH SAN FRANCISCO, CALIFORNIA 94080
                                    (415) 829-1000
            (Address and telephone number of principal executive offices)

                         ------------------------------
                                   1989 STOCK PLAN
                             EMPLOYEE STOCK PURCHASE PLAN

                                    JOHN P. WALKER
                        PRESIDENT AND CHIEF EXECUTIVE OFFICER
                           ARRIS PHARMACEUTICAL CORPORATION
                         385 OYSTER POINT BOULEVARD, SUITE 3
                        SOUTH SAN FRANCISCO, CALIFORNIA 94080
                                    (415) 829-1000
(Name, address, including zip code, and telephone number, including area code,
of agent for service)

                          ----------------------------
                                      Copies to:
                               ALAN C. MENDELSON, ESQ.
                                GREGORY C. SMITH, ESQ.
                       COOLEY GODWARD CASTRO HUDDLESON & TATUM
                                FIVE PALO ALTO SQUARE
                                 3000 EL CAMINO REAL
                             PALO ALTO, CALIFORNIA 94306
                                    (415) 843-5000

                          ----------------------------

<TABLE>
<CAPTION>
                           CALCULATION OF REGISTRATION FEE
- -------------------------------------------------------------------------------------------------------
TITLE OF                               PROPOSED MAXIMUM         PROPOSED MAXIMUM
SECURITIES             AMOUNT TO BE     OFFERING PRICE PER     AGGREGATE OFFERING        AMOUNT OF
TO BE REGISTERED       REGISTERED          SHARE (1)               PRICE (1)          REGISTRATION FEE
- -------------------------------------------------------------------------------------------------------
<S>                    <C>              <C>                    <C>                    <C>
Stock Options and
Common Stock (par
value $.001)             650,000             $10.75                $6,987,500            $2,409.49
- -------------------------------------------------------------------------------------------------------
- -------------------------------------------------------------------------------------------------------
</TABLE>

(1) Estimated solely for the purpose of calculating the amount of the
    registration fee pursuant to Rule 457(c).  The offering price is based upon
    the average high and low price on July 24, 1996, as reported on the Nasdaq
    National Market, pursuant to Rule 475(h) under the Securities Act of 1933,
    as amended (the "Securities Act").


<PAGE>

                                        PART II

ITEM 3.  INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE.

    The following documents filed by the Company with the Securities and
Exchange Commission are incorporated by reference into this Registration
Statement:

    (a)  The Company's Annual Report on Form 10-K for the year ended December
31, 1995 (File No. 0-22788), including all material incorporated by reference
therein;

    (b)  The Company's Quarterly Report on Form 10-Q for the quarter ended
March 31, 1996 (File No. 0-22788), as amended, including all material
incorporated by reference therein;

    (c)  The Company's Current Report on Form 8-K (File No. 0-21888), dated
January 5, 1996; and

    (d)  The description of the Common Stock contained in the Company's
Registration Statement on Form 8-A (File No. 0-22788).

    All reports and other documents subsequently filed by the Company pursuant
to Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act of 1934,
as amended (the "Exchange Act") prior to the filing of a post-effective
amendment which indicates that all securities offered have been sold or which
deregisters all securities then remaining unsold, shall be deemed to be
incorporated by reference herein and to be a part of this registration statement
from the date of the filing of such reports and documents.

ITEM 4.  DESCRIPTION OF SECURITIES

    Not Applicable

ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.

    The validity of the shares of Common Stock offered hereby will be passed
upon for the Company by Cooley Godward Castro Huddleson & Tatum ("CGCH&T"), Palo
Alto, California.  CGCH&T and certain attorneys in such firm own an aggregate of
approximately 10,108 shares of the Company's Common Stock.  Alan C. Mendelson, a
partner of CGCH&T, is the Secretary of the Company.

ITEM 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS.

    Under Section 145 of the Delaware General Corporation Law the Company has
broad powers to indemnify its directors and officers against liabilities they
may incur in such capacities, including liabilities under the Securities Act.
The Company's Bylaws also provide the Company will indemnify its directors and
executive officers, and may indemnify its other officers, employees and other
agents, to the fullest extent not prohibited by Delaware law.

    The Company's Certificate of Incorporation provides for the elimination of
liability for monetary damages for breach of the directors' fiduciary duty of
care to the Company and its stockholders. These provisions do not eliminate the
directors' duty of care and, in appropriate circumstances, equitable remedies
such an injunctive or other forms of non-monetary relief will remain available
under Delaware law.  In addition, each director will continue to be subject to
liability for breach of the director's duty of loyalty to the Company, for acts
or omissions not in good faith or involving intentional misconduct, for knowing
violations of law, for any transaction from which the director derived an
improper personal benefit, and for payment of dividends or approval of stock
repurchases or redemptions that are unlawful under Delaware law.  The provision
does not affect a director's responsibilities under any other laws, such as the
federal securities laws or state or federal environmental laws.

    The Company has entered into agreements with its directors and executive
officers that require the Company to indemnify such persons against expenses,
judgments, fines, settlements and other amounts actually and reasonably incurred
(including expenses of a derivative action) in connection with any proceeding,
whether actual or threatened, to which any such person may be made a party by
reason of the fact that such person is or was a director or officer of the
Company or any of its affiliated enterprises, provided such person acted in good
faith and in a manner such person reasonably believed to be in or not opposed to
the best interests of the Company and, with respect to any criminal proceeding,
had no reasonable cause to believe his or her conduct was unlawful.  The
indemnification agreements also set forth certain procedures that will apply in
the event of a claim for indemnification thereunder.

    In addition, the Company has entered into certain agreements in connection
with the Company's equity financings which provide for the indemnification of
directors and officers in certain circumstances, including indemnification for
liabilities arising under the Securities Act of 1933, as amended.  The Company
also

                                         II-1

<PAGE>

maintains an insurance policy for its directors and officers insuring against
certain liabilities arising in their capacities as such.

ITEM 7.  EXEMPTION FROM REGISTRATION CLAIMED

    Not Applicable

ITEM 8.  EXHIBITS.

EXHIBIT
NUMBER
- -------

5.1      Opinion of Cooley Godward Castro Huddleson & Tatum.

23.1     Consent of Ernst & Young LLP, Independent Auditors.

23.2     Consent of Cooley Godward Castro Huddleson & Tatum.  Reference is made
         to Exhibit 5.1.

24.1     Power of Attorney.  Reference is made to the Signature Page.

99.1     1989 Stock Plan, as amended.

99.2     Form of Stock Option Agreement used in connection with the 1989 Stock
         Option Plan, as amended.(1)

99.3     Employee Stock Purchase Plan, as amended.

99.4     Employee Stock Purchase Plan Offering
- --------------

(1) Incorporated herein by reference to Exhibit 10.2 to the Registrant's
    Registration Statement on Form S-1, File No. 33-69972.

ITEM 9.  UNDERTAKINGS.

    A.   The undersigned registrant hereby undertakes:

         (1)  To file, during any period in which offers or sales are being
made, a post-effective amendment to this registration statement:

              (i)  To include any prospectus required by section 10(a)(3) of
              the Securities Act of 1933;

              (ii) To reflect in the prospectus any facts or events arising
              after the effective date of the registration statement (or the
              most recent post-effective amendment thereof) which, individually
              or in the aggregate, represent a fundamental change in the
              information set forth in the registration statement.
              Notwithstanding the foregoing, any increase or decrease in volume
              of securities offered (if the total dollar value of securities
              offered would not exceed that which was registered) and any
              deviation from the low or high and of the estimated maximum
              offering range may be reflected in the form of prospectus filed
              with the Commission pursuant to Rule 424(b) if, in the aggregate,
              the changes in volume and price represent no more than 20 percent
              change in the maximum aggregate offering price set forth in the
              "Calculation of Registration Fee" table in the effective
              registration statement;

              (iii)  To include any material information with respect to the
              plan of distribution not previously disclosed in the registration
              statement or any material change to such information in the
              registration statement;

provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the
Commission by the registrant pursuant to Section 13 or 15(d) of the Securities
Exchange Act of 1934 that are incorporated by reference in the registration
statement.

         (2)  That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered

                                         II-2
<PAGE>

herein, and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.

         (3)  To remove from registration by means of a post-effective
amendment any of the securities being registered which remain unsold at the
termination of the offering.

    B.   The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan's
annual report pursuant to section 15(d) of the Exchange Act) that is
incorporated by reference in the Registration Statement shall be deemed to be a
new registration statement relating to the securities offered herein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

    C.   Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the registrant pursuant to the foregoing provisions, or otherwise, the
registrant has been advised that in the opinion of the Securities and Exchange
Commission such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable.  In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Securities
Act and will be governed by the final adjudication of such issue.


                                         II-3

<PAGE>
                                       SIGNATURES

    THE REGISTRANT.  Pursuant to the requirements of the Securities Act of
1933, as amended, the Registrant certifies that it has reasonable grounds to
believe that it meets all of the requirements for filing on Form S-8 and has
duly caused this Registration Statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the City of South San Francisco,
State of California, on July 29, 1996.


                                       ARRIS PHARMACEUTICAL CORPORATION




                                       By: /s/ John P. Walker
                                          ------------------------------------
                                                  John P. Walker
                                                  PRESIDENT, CHIEF EXECUTIVE
                                                  OFFICER AND DIRECTOR




                                  POWER OF ATTORNEY

    KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature
appears below constitutes and appoints John P. Walker and Daniel H. Petree, and
each or any one of them, his true and lawful attorney-in-fact and agent, with
full power of substitution and resubstitution, for him and in his name, place
and stead, in any and all capacities, to sign any and all amendments (including
post-effective amendments) to this Registration Statement, and to file the same,
with all exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, granting unto said attorneys-in-fact and
agents, and each of them, full power and authority to do and perform each and
every act and thing requisite and necessary to be done in connection therewith,
as fully to all intents and purposes as he might or could do in person, hereby
ratifying and confirming all that said attorneys-in-fact and agents, or any of
them, or their or his substitutes or substitute, may lawfully do or cause to be
done by virtue hereof.

                                         II-4

<PAGE>

     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.


SIGNATURE               TITLE                              DATE

/s/ John P. Walker      President, Chief Executive         July 29, 1996
- ------------------      Officer and Director
  John P. Walker        (PRINCIPAL EXECUTIVE OFFICER)
 


/s/ Daniel H. Petree    Vice President, Corporate          July 29, 1996
- --------------------    Development and Chief
  Daniel H. Petree      Financial Officer
                        (PRINCIPAL FINANCIAL AND
                        ACCOUNTING OFFICER)


/s/ Brook H. Byers      Director                           July 29, 1996
- ------------------
  Brook H. Byers


/s/ Anthony B. Evnin    Director                           July 29, 1996
- --------------------
  Anthony B. Evnin


/s/ Michael J. Ross     Director                           July 29, 1996
- -------------------
  Michael J. Ross


- -------------------     Director                           July   , 1996
Hans U. Sievertsson


/s/ Vaughn Kailian      Director                           July 29, 1996
- ------------------
  Vaughn Kailian


                                         II-5

<PAGE>
                                     EXHIBIT INDEX


EXHIBIT
NUMBER                               DESCRIPTION

 5.1     Opinion of Cooley Godward Castro Huddleson & Tatum.
23.1     Consent of Ernst & Young LLP, Independent Auditors
23.2     Consent of Cooley Godward Castro Huddleson & Tatum.  Reference is made
         to Exhibit 5.1.
24.1     Power of Attorney.  Reference is made to the Signature Page.
99.1     1989 Stock Plan, as amended
99.2     Form of Stock Option Agreement used in connection with the 1989 Stock
         Option Plan, as amended.(1)
99.3     Employee Stock Purchase Plan, as amended.
99.4     Employee Stock Purchase Plan Offering Document

- --------------

(1) Incorporated herein by reference to Exhibit 10.2 to the Registrant's
    Registration Statement on Form S-1, File No. 33-69972.

                                         II-6




<PAGE>

                                                                     Exhibit 5.1




ALAN C. MENDELSON
DIRECT: (415) 843-5010
INTERNET: [email protected]


July 29, 1996


Arris Pharmaceutical Corp.
385 Oyster Point Blvd.
Suite 3
South San Francisco, CA  94080

Ladies and Gentlemen:

You have requested our opinion with respect to certain matters in connection
with the filing by Arris Pharmaceutical Corp. (the "Company") of a Registration
Statement on Form S-8 (the "Registration Statement") with the Securities and
Exchange Commission covering the offering of up to 650,000 shares of the
Company's Common Stock, $0.001 par value, (the "Shares") pursuant to its 1989
Stock Plan, as amended, and the Employee Stock Purchase Plan, as amended (the
"Plans").

In connection with this opinion, we have examined the Registration Statement and
related Prospectus, your Certificate of Incorporation and Bylaws, as amended,
and such other documents, records, certificates, memoranda and other instruments
as we deem necessary as a basis for this opinion.  We have assumed the
genuineness and authenticity of all documents submitted to us as originals, the
conformity to originals of all documents submitted to us as copies thereof, and
the due execution and delivery of all documents where due execution and delivery
are a prerequisite to the effectiveness thereof.

On the basis of the foregoing, and in reliance thereon, we are of the opinion
that the Shares, when issued in accordance with the Plan, the Registration
Statement and related Prospectus, will be validly issued, fully paid, and
nonassessable (except as to shares issued pursuant to certain deferred payment
arrangements, which will be fully paid and nonassessable when such deferred
payments are made in full).

We consent to the filing of this opinion as an exhibit to the Registration
Statement.

Very truly yours,

COOLEY GODWARD CASTRO
HUDDLESON & TATUM



By:
   --------------------------
    Alan C. Mendelson

cc: Daniel H. Petree




<PAGE>

                                                                    Exhibit 23.1





                  Consent of Ernst & Young LLP, Independent Auditors



We consent to the incorporation by reference in this Registration Statement
(Form S-8) pertaining to the 1989 Stock Plan and Employee Stock Purchase Plan of
Arris Pharmaceutical Corporation of our report dated January 20, 1996 with
respect to the consolidated financial statements of Arris Pharmaceutical
Corporation included in the Annual Report (Form 10-K) for the year ended
December 31, 1995, filed with the Securities and Exchange Commission.


                                  /s/ Ernst & Young LLP


Palo Alto, California
July 25, 1996

<PAGE>

                                                                    Exhibit 99.1




                           ARRIS PHARMACEUTICAL CORPORATION

                                   1989 STOCK PLAN

                                 ADOPTED MAY 16, 1989
                        AS AMENDED BY THE BOARD MARCH 25, 1992
                       APPROVED BY STOCKHOLDERS MARCH 25, 1992
                        AS AMENDED BY THE BOARD APRIL 6, 1993
                       APPROVED BY STOCKHOLDERS OCTOBER 5, 1993
                        AS AMENDED BY THE BOARD APRIL 20, 1994
                        APPROVED BY STOCKHOLDERS JUNE 7, 1994
                       AS AMENDED BY THE BOARD FEBRUARY 8, 1995
                        APPROVED BY STOCKHOLDERS JUNE 7, 1995
                      AS AMENDED BY THE BOARD FEBRUARY 27, 1996
                        APPROVED BY STOCKHOLDERS JUNE 5, 1996

    1.   PURPOSES OF THE PLAN.  The purposes of this Stock Plan are to attract
and retain the best available personnel for positions of substantial
responsibility, to provide additional incentive to Employees and Consultants of
the Company and its Subsidiaries and to promote the success of the Company's
business.  Options granted under the Plan may be incentive stock options (as
defined under Section 422 of the Code) or non-statutory stock options, as
determined by the Administrator at the time of grant of an option and subject to
the applicable provisions of Section 422 of the Code, as amended, and the
regulations promulgated thereunder.  Stock purchase rights may also be granted
under the Plan.

    2.   DEFINITIONS.  As used herein, the following definitions shall apply:

         (a)  "ADMINISTRATOR" means the Board or any of its Committees
appointed pursuant to Section 4 of the Plan.

         (b)  "BOARD" means the Board of Directors of the Company.

         (c)  "CODE" means the Internal Revenue Code of 1986, as amended.

         (d)  "COMMITTEE" means the Committee appointed by the Board of
Directors in accordance with paragraph (a) of Section 4 of the Plan.

         (e)  "COMMON STOCK" means the Common Stock of the Company.

         (f)  "COMPANY" means Arris Pharmaceutical Corporation, a Delaware
corporation.

         (g)  "CONSULTANT" means any person, including an advisor, who is
engaged by the Company or any Parent or Subsidiary to render services and is
compensated for such services, and any director of the Company whether
compensated for such services or not;

                                          1

<PAGE>

provided that if and in the event the Company registers any class of any equity
security pursuant to the Exchange Act, the term Consultant shall thereafter not
include directors who are not compensated for their services or are paid only a
director's fee by the Company.

         (h)  "CONTINUOUS STATUS AS AN EMPLOYEE" means the absence of any
interruption or termination of the employment relationship by the Company or any
Subsidiary.  Continuous Status as an Employee shall not be considered
interrupted in the case of:  (i) sick leave; (ii) military leave; (iii) any
other leave of absence approved by the Board, provided that such leave is for a
period of not more than ninety (90) days, unless reemployment upon the
expiration of such leave is guaranteed by contract or statute, or unless
provided otherwise pursuant to Company policy adopted from time to time; or (iv)
in the case of transfers between locations of the Company or between the
Company, its Subsidiaries or its successor.

         (i)  "DISINTERESTED PERSON" means a Director who either (i) was not
during the one year prior to service as an administrator of the Plan granted or
awarded equity securities pursuant to the Plan or any other plan of the Company
or any of its affiliates entitling the participants therein to acquire equity
securities of the Company or any of its affiliates except as permitted by
Rule 16b-3(c)(2)(i); or (ii) who is otherwise considered to be a "disinterested
person" in accordance with Rule 16b-3(c)(2)(i), or any other applicable rules,
regulations or interpretations of the Securities and Exchange Commission.

         (j)  "EMPLOYEE" means any person, including officers and directors,
employed by the Company or any Parent or Subsidiary of the Company.  The payment
of a director's fee by the Company shall not be sufficient to constitute
"employment" by the Company.

         (k)  "EXCHANGE ACT" means the Securities Exchange Act of 1934, as
amended.

         (l)  "FAIR MARKET VALUE" means the value of the common stock of the
Company as determined in good faith by the Administrator.

         (m)  "INCENTIVE STOCK OPTION" means an Option intended to qualify as
an incentive stock option within the meaning of Section 422 of the Code.

         (n)  "NONSTATUTORY STOCK OPTION" means an Option not intended to
qualify as an Incentive Stock Option.

         (o)  "OPTION" means a stock option granted pursuant to the Plan.

         (p)  "OPTIONED STOCK" means the Common Stock subject to an Option.

         (q)  "OPTIONEE" means an Employee or Consultant who receives an
Option.

         (r)  "OUTSIDE DIRECTOR" means a Director who either (i) is not a
current employee of the Company or an affiliated corporation, is not a former
employee of the Company or an affiliated corporation receiving compensation for
prior services (other than benefits under

                                          2

<PAGE>

a tax qualified pension plan), was not an officer of the Company or an
affiliated corporation at any time, and is not currently receiving compensation
for personal services in any capacity other than as a Director, or (ii) is
otherwise considered an "outside director" for purposes of Section 162(m) of the
Code.

         (s)  "PARENT" means a "parent corporation", whether now or hereafter
existing, as defined in Section 425(e) of the Code.

         (t)  "PLAN" means this 1989 Stock Plan.

         (u)  "RESTRICTED STOCK" means shares of Common Stock acquired pursuant
to a grant of Stock Purchase Rights under Section 11 below.

         (v)  "RULE 16B-3" means Rule 16b-3 of the Exchange Act or any
successor to Rule 16b-3, as in effect when discretion is being exercised with
respect to the Plan.

         (w)  "SHARE" means a share of the Common Stock, as adjusted in
accordance with Section 13 of the Plan.

         (x)  "STOCK PURCHASE RIGHT" means the right to purchase Restricted
Stock in accordance with the provisions of Section 11 below.

         (y)  "SUBSIDIARY" means a "subsidiary corporation," whether now or
hereafter existing, as defined in Section 425(f) of the Code.

    3.   STOCK SUBJECT TO THE PLAN.  Subject to the provisions of Section 13 of
the Plan, the maximum aggregate number of shares which may be optioned and sold
under the Plan is two million six hundred sixty-seven thousand five hundred
(2,667,500) shares of Common Stock.  The shares may be authorized, but unissued,
or reacquired Common Stock.

    If an Option should expire or become unexercisable (for any reason) without
having been exercised in full, the unpurchased Shares which were subject thereto
shall, unless the Plan shall have been terminated, become available for future
grant under the Plan.

    4.   ADMINISTRATION OF THE PLAN.

         (a)  PROCEDURE.  The Board may delegate administration of the Plan to
a committee composed of not fewer than two (2) members (the "Committee"), all of
the members of which Committee shall be Disinterested Persons and may also be,
in the discretion of the Board, Outside Directors.  If administration is
delegated to a Committee, the Committee shall have, in connection with the
administration of the Plan, the powers theretofore possessed by the Board (and
references in this Plan to the Board shall thereafter be to the Committee),
subject, however, to such resolutions, not inconsistent with the provisions of
the Plan, as may be adopted from time to time by the Board.  The Board may
abolish the Committee at any time and revest in the Board the administration of
the Plan.  Notwithstanding anything in this Section 4 to the

                                          3

<PAGE>

contrary, the Board or the Committee may delegate to a committee of one or more
members of the Board the authority to grant options to eligible persons who are
not then subject to Section 16 of the Exchange Act and to eligible persons with
respect to whom the Company does not wish to comply with Section 162(m) of the
Code.

         Any requirement that an administrator of the Plan be a Disinterested
Person shall not apply if the Board or the Committee expressly declares that
such requirement shall not apply.  Any Disinterested Person shall otherwise
comply with the requirements of Rule 16b-3.

         (b)  POWERS OF THE ADMINISTRATOR.  Subject to the provisions of the
Plan and in the case of a duly authorized committee, the specific duties
delegated by the Board to such duly authorized committee, the Administrator
shall have the authority, in its discretion:

              (i)  to determine the Fair Market Value of the Common Stock, in
accordance with Section 2(k) of the Plan;

              (ii) to select the officers, Consultants and Employees to whom
Options and Stock Purchase Rights may from time to time be granted hereunder;

              (iii)     to determine whether and to what extent Options and
Stock Purchase Rights or any combination thereof, are granted hereunder;

              (iv) to determine the number of shares of Common Stock to be
covered by each such award granted hereunder;

              (v)  to approve forms of agreement for use under the Plan;

              (vi) to determine the terms and conditions, not inconsistent with
the terms of the Plan, of any award granted hereunder (including, but not
limited to, the share price and any restriction or limitation, regarding any
Option or other award and/or the shares of Common Stock relating thereto, based
in each case on such factors as the Administrator shall determine, in its sole
discretion);

              (vii)     to determine whether and under what circumstances an
Option may be settled in cash under subsection 9(f) instead of Common Stock;

              (viii)    to determine whether, to what extent and under what
circumstances Common Stock and other amounts payable with respect to an award
under this Plan shall be deferred either automatically or at the election of the
participant (including providing for and determining the amount, if any, of any
deemed earnings on any deferred amount during any deferral period);

              (ix) to reduce the exercise price of any Option to the then
current Fair Market Value if the Fair Market Value of the Common Stock covered
by such Option shall have declined since the date the Option was granted; and

                                          4

<PAGE>

              (x)  to determine the terms and restrictions applicable to Stock
Purchase Rights and the Restricted Stock purchased by exercising such Stock
Purchase Rights.

         (c)  EFFECT OF COMMITTEE'S DECISION.  All decisions, determinations
and interpretations of the Administrator shall be final and binding on all
Optionees and any other holders of awards granted under the Plan.

    5.   ELIGIBILITY.

         (a)  Stock Purchase Rights may be granted to Employees and
Consultants.

         (b)  Nonstatutory Stock Options may be granted to Employees and
Consultants.  Incentive Stock Options may be granted only to Employees.  An
Employee or Consultant who has been granted an Option may, if he is otherwise
eligible, be granted an additional Option or Options.

         (c)  A director shall in no event be eligible for the benefits of the
Plan unless at the time discretion is exercised in the selection of the director
as a person to whom Options may be granted, or in the determination of the
number of shares which may be covered by Options granted to the director:
(A) the Board has delegated its discretionary authority over the Plan to a
Committee which consists solely of Disinterested Persons; or (B) the Plan
otherwise complies with the requirements of Rule 16b-3.  The Board shall
otherwise comply with the requirements of Rule 16b-3.  This subsection 5(c)
shall not apply if the Board or Committee expressly declares that it shall not
apply.

         (d)  Each Option shall be designated in the written option agreement
as either an Incentive Stock Option or a Nonstatutory Stock Option.  However,
notwithstanding such designations, to the extent that the aggregate Fair Market
Value of the Shares with respect to which Options designated as Incentive Stock
Options are exercisable for the first time by any Optionees during any calendar
year (under all plans of the Company or any Parent or Subsidiary) exceeds
$100,000, such excess Options shall be treated as Nonstatutory Stock Options.

         (e)  No person shall be eligible to be granted Options covering more
than three hundred thousand (300,000) shares of the Company's Common Stock in
any calendar year.

         (f)  For purposes of Section 5(d), Incentive Stock Options shall be
taken into account in the order in which they were granted, and the Fair Market
Value of the Shares shall be determined as of the time the Option with respect
to such Shares is granted.

         (g)  The Plan shall not confer upon any grantee of an award under the
Plan any right with respect to continuation of employment or consulting
relationship with the Company, nor shall it interfere in any way with his right
or the Company's right to terminate his employment or consulting relationship at
any time, with or without cause.

                                          5

<PAGE>


    6.   TERM OF PLAN.  The Plan shall be come effective upon the earlier to
occur of its adoption by the Board of Directors or its approval by the
Shareholders of the Company as described in Section 19 of the Plan.  It shall
continue in effect for a term of ten (10) years unless sooner terminated under
Section 15 of the Plan.

    7.   TERM OF OPTION.  The term of each Option shall be the term stated in
the Option Agreement; provided, however, that in the case of an Incentive Stock
Option, the term shall be no more than ten (10) years from the date of grant
thereof or such shorter term as may be provided in the Option Agreement.
However, in the case of an Option granted to an Optionee who, at the time the
Option is granted, owns stock representing more than ten percent (10%) of the
voting power of all classes of stock of the Company or any Parent or Subsidiary,
the term of the Option shall be five (5) years from the date of grant thereof or
such shorter term as may be provided in the Option Agreement.

    8.   OPTION EXERCISE PRICE AND CONSIDERATION.

         (a)  The per share exercise price for the Shares to be issued pursuant
to exercise of an Option shall be such price as is determined by the Board, but
shall be subject to the following:

              (i)  In the case of an Incentive Stock Option

                   (A)  granted to an Employee who, at the time of the grant of
such Incentive Stock Option, owns stock representing more than ten percent (10%)
of the voting power of all classes of stock of the Company or any Parent or
Subsidiary, the per Share exercise price shall be no less than 110% of the Fair
Market Value per Share on the date of grant.

                   (B)  granted to any Employee, the per Share exercise price
shall be no less than 100% of the Fair Market Value per Share on the date of
grant.

              (ii) In the case of a Nonstatutory Stock Option

                   (A)  granted to a person who, at the time of the grant of
such Option, owns stock representing more than ten percent (10%) of the voting
power of all classes of stock of the Company or any Parent of Subsidiary, the
per Share exercise price shall be no less than 110% of the Fair Market Value per
Share on the date of the grant.

                   (B)  granted to any person, the per Share exercise price
shall be no less than 85% of the Fair Market Value per Share on the date of
grant.

         (b)  The consideration to be paid for the Shares to be issued upon
exercise of an Option, including the method of payment, shall be determined by
the Administrator (and, in the case of an Incentive Stock Option, shall be
determined at the time of grant) and may consist entirely of (1) cash, (2)
check, (3) promissory note, (4) other Shares which (x) in the case of Shares
acquired upon exercise of an Option either have been owned by the Optionee for
more

                                          6

<PAGE>

than six months on the date of surrender or were not acquired, directly or
indirectly, from the Company, and (y) have a Fair Market Value on the date of
surrender equal to the aggregate exercise price of the Shares as to which said
Option shall be exercised, (5) authorization from the Company to retain from the
total number of Shares as to which the Option is exercised that number of Shares
having a Fair Market Value on the date of exercise equal to the exercise price
for the total number of Shares as to which the Option is exercised, (6) delivery
of a properly executed exercise notice together with irrevocable instructions to
a broker to promptly deliver to the Company the amount of sale or loan proceeds
required to pay the exercise price, (7) by delivering an irrevocable
subscription agreement for the Shares which irrevocably obligates the option
holder to take and pay for the Shares not more than twelve months after the date
of delivery of the subscription agreement, (8) any combination of the foregoing
methods of payment, (9) or such other consideration and method of payment for
the issuance of Shares to the extent permitted under Applicable Laws.  In making
its determination as of the type of consideration to accept, the Board shall
consider if acceptance of such consideration may be reasonably expected to
benefit the Company (Section 153 of the Delaware Corporation law).

    9.   EXERCISE OF OPTION.

         (a)  PROCEDURE FOR EXERCISE; RIGHTS AS A SHAREHOLDER.  Any Option
granted hereunder shall be exercisable at such times and under such conditions
as determined by the Board, including performance criteria with respect to the
Company and/or the Optionee, and as shall be permissible under the terms of the
Plan.

              An Option may not be exercised for a fraction of a Share.

              An Option shall be deemed to be exercised when written notice of
such exercise has been given to the Company in accordance with the terms of the
Option by the person entitled to exercise the Option and full payment for the
Shares with respect to which the Option is exercised has been received by the
Company.  Full payment may, as authorized by the Board, consist of any
consideration and method of payment allowable under Section 8(b) of the Plan.
Until the issuance (as evidenced by the appropriate entry on the books of the
Company or of a duly authorized transfer agent of the Company) of the stock
certificate evidencing such Shares, no right to vote or receive dividends or any
other rights as a shareholder shall exist with respect to the Optioned Stock,
notwithstanding the exercise of the Option.  The Company shall issue (or cause
to be issued) such stock certificate promptly upon exercise of the Option.  No
adjustment will be made for a divided or other right for which the record date
is prior to the date the stock certificate is issued, except as provided in
Section 13 of the Plan.

    Exercise of an Option in any manner shall result in a decrease in the
number of Shares which thereafter may be available, both for purposes of the
Plan and for sale under the Option, by the number of Shares as to which the
Option is exercised.

         (b)  TERMINATION OF EMPLOYMENT.  In the event of termination of an
Optionee's consulting relationship or Continuous Status as an Employee with the
Company (as the case may be), such Optionee may, but only within ninety (90)
days (or such other period of



                                          7

<PAGE>

time as is determined by the Board, with such determination in the case of an
Incentive Stock Option being made at the time of grant of the Option and not
exceeding ninety (90) days) after the date of such termination (but in no event
later than the expiration date of the term of such Option as set forth in the
Option Agreement), exercise his Option of the extent that Optionee was entitled
to exercise it at the date of such termination.  To the extent that Optionee was
not entitled to exercise the Option at the date of such termination, or if
Optionee does not exercise such Option to the extent so entitled within the time
specified herein, the Option shall terminate.

         (c)  DISABILITY OF OPTIONEE.  Notwithstanding the provisions of
Section 9(b) above, in the event of termination of an Optionee's Consulting
relationship or Continuous Status as an Employee as a result of his total and
permanent disability (as defined in Section 22(e)(3) of the Code), Optionee may,
but only within twelve (12) months from the date of such termination (but in no
event later than the expiration date of the term of such Option as set forth in
the Option Agreement), exercise the Option to the extent otherwise entitled to
exercise it at the date of such termination.  To the extent that Optionee was
not entitled to exercise the Option at the date of termination, or if Optionee
does not exercise such Option to the extent so entitled within the time
specified herein, the Option shall terminate.

         (d)  DEATH OF OPTIONEE.  In the event of the death of an Optionee, the
Option may be exercised, at any time within twelve (12) months following the
date of death (but in no event later than the expiration date of the term of
such Option as set forth in the Option Agreement), by the Optionee's estate or
by a person who acquired the right to exercise the Option by bequest or
inheritance, but only to the extent the Optionee was entitled to exercise the
Option at the date of death.  To the extent that Optionee was not entitled to
exercise the Option at the date of termination, or if Optionee does not exercise
such Option to the extent so entitled within the time specified herein, the
Option shall terminate.

         (e)  RULE 16B-3.  Options granted to persons subject to Section l6(b)
of the Exchange Act must comply with Rule 16-3 and shall contain such additional
conditions or restrictions as may be required thereunder to qualify for the
maximum exemption from Section 16 of the Exchange Act with respect to Plan
transactions.

         (f)  BUYOUT PROVISIONS.  The Administrator may at any time offer to
buy out for a payment in cash or Shares, an Option previously granted, based on
such terms and conditions as the Administrator shall establish and communicate
to the Optionee at the time that such offer is made.

    10.  NON-TRANSFERABILITY OF OPTIONS.  The Option may not be sold, pledged,
assigned, hypothecated, transferred, or disposed of in any manner other than by
will or by the laws of descent or distribution and may be exercised, during the
lifetime of the Optionee, only by the Optionee.

                                          8

<PAGE>




    11.  STOCK PURCHASE RIGHTS.

         (a)  RIGHTS TO PURCHASE.  Stock Purchase Rights may be issued either
alone, in addition to, or in tandem with other awards granted under the Plan
and/or cash awards made outside of the Plan. After the Administrator determines
that it will offer Stock Purchase Rights under the Plan, it shall advise the
offeree in writing of the terms, conditions and restrictions related to the
offer, including the number of Shares that such person shall be entitled to
purchase, the price to be paid (which price shall not be less than 50% of the
Fair Market Value of the Shares as of the date of the offer), and the time
within which such person must accept such offer, which shall not exceed thirty
(30) days (or such longer time as may be determined by the Administrator)  from
the date upon which the Administrator made the determination to grant the Stock
Purchase Right.  The offer shall be accepted by execution of a Restricted Stock
purchase agreement in the form determined by the Administrator.  Shares
purchased pursuant to the grant of a Stock Purchase Right shall be referred to
herein as "Restricted Stock."

         (b)  REPURCHASE OPTION.  Unless the Administrator determines
otherwise, the Restricted Stock purchase agreement shall grant the Company a
repurchase option exercisable upon the voluntary or involuntary termination of
the purchaser's employment with the Company for any reason (including death or
disability).  The purchase price for Shares repurchased pursuant to the
Restricted Stock purchase agreement shall be the original price paid by the
purchaser and may be paid by cancellation of any indebtedness of the purchaser
to the Company.  The repurchase option shall lapse at such rate as the Committee
may determine.

         (c)  OTHER PROVISIONS.  The Restricted Stock purchase agreement 
shall contain such other terms, provisions and conditions not inconsistent 
with the Plan as may be determined by the Administrator in its sole 
discretion.   In addition, the provisions of Restricted Stock purchase 
agreements need not be the same with respect to each purchaser.

         (d)  RIGHTS AS A STOCKHOLDER.  Once the Stock Purchase Right is
exercised, the purchaser shall have the rights equivalent to those of a
stockholder, and shall be a shareholder when his or her purchase is entered upon
the records of the duly authorized transfer agent of the Company.  No adjustment
will be made for a dividend or other right for which the record date is prior to
the date the Stock Purchase Right is exercised, except as provided in Section 13
of the Plan.

    12.  STOCK WITHHOLDING TO SATISFY WITHHOLDING TAX OBLIGATIONS.  At the
discretion of the Administrator, grantees of an Option or Stock Purchase Right
may satisfy withholding obligations as provided in this paragraph.  When a
grantee incurs tax liability in connection with an Option or Stock Purchase
Right, which tax liability is subject to tax withholding under applicable tax
laws, and the grantee is obligated to pay the Company an amount required to be
withheld under applicable tax laws, the grantee may satisfy the withholding tax
obligation by electing to have the Company withhold from the Shares to be issued
upon exercise of the Option, or the Shares to be issued in connection with the
Stock Purchase Right, if any, that number of Shares having a Fair Market Value
equal to the amount required to be withheld.  The Fair Market Value of the
Shares to be withheld shall be

                                          9

<PAGE>

determined on the date that the amount of tax to be withheld is to be determined
(the "Tax Date").

    All elections by a grantee to have Shares withheld for this purpose shall
be made in writing in a form acceptable to the Administrator and shall be
subject to the following restrictions:

         (a)  the election must be made on or prior to the applicable Tax Date;

         (b)  once made, the election shall be irrevocable as to the particular
Shares of the Option or Right as to which the election is made;

         (c)  all elections shall be subject to the consent or disapproval of
the Administrator;

         (d)  if the grantee is subject to Rule l6b-3, the election must comply
with the applicable provisions of Rule l6b-3 and shall be subject to such
additional conditions or restrictions as may be required thereunder to qualify
for the maximum exemption from Section 16 of the Exchange Act with respect to
Plan transactions.

    In the event the election to have Shares withheld is made by a grantee and
the Tax Date is deferred under Section 83 of the Code because no election is
filed under Section 83(b) of the Code, the grantee shall receive the full number
of Shares with respect to which the Option or Stock Purchase Right is exercised
but such grantee shall be unconditionally obligated to tender back to the
Company the proper number of Shares on the Tax Date.

    13.  ADJUSTMENTS UPON CHANGES IN CAPITALIZATION OR MERGER.  Subject to any
required action by the shareholders of the Company, the number of shares of
Common Stock covered by each outstanding Option, and the number of shares of
Common Stock which have been authorized for issuance under the Plan but as to
which no Options have yet been granted or which have been returned to the Plan
upon cancellation or expiration of an Option, as well as the price per share of
Common Stock covered by each such outstanding Option, shall be proportionately
adjusted for any increase or decrease in the number of issued shares of Common
Stock resulting from a stock split, reverse stock split, stock dividend,
combination or reclassification of the Common Stock, or any other increase or
decrease in the number of issued shares of Common Stock effected without receipt
of consideration by the Company; provided, however, that conversion of any
convertible securities of the Company shall not be deemed to have been "effected
without receipt of consideration."  Such adjustment shall be made by the Board,
whose determination in that respect shall be final, binding and conclusive.
Except as expressly provided herein, no issuance by the Company of shares of
stock of any class, or securities convertible into shares of stock of any class,
shall affect, and no adjustment by reason thereof shall be made with respect to,
the number or price of shares of Common Stock subject to an Option.

                                          10

<PAGE>

    In the event of the proposed dissolution or liquidation of the Company, the
Board shall notify the Optionee at least fifteen (15) days prior to such
proposed action.  To the extent it has not been previously exercised, the Option
will terminate immediately prior to the consummation of such proposed action.
In the event of a merger of the Company with or into another corporation, the
Option shall be assumed or an equivalent option shall be substituted by such
successor corporation or a parent or subsidiary of such successor corporation.

    14.  TIME OF GRANTING OPTIONS.  The date of grant of an Option shall, for
all purposes, be the date on which the Administrator makes the determination
granting such Option, or such other date as is determined by the Board.  Notice
of the determination shall be given to each Employee or Consultant to whom an
Option is so granted within a reasonable time after the date of such grant.

    15.  AMENDMENT AND TERMINATION OF THE PLAN.

         (a)  AMENDMENT AND TERMINATION.  The Board may at any time amend,
alter, suspend or discontinue the Plan, but no amendment, alteration, suspension
or discontinuation shall be made which would impair the rights of any grantee
under any grant theretofore made, without his or her consent.  In addition, to
the extent necessary and desirable to comply with Rule 16b-3 under the Exchange
Act or with Sections 162(m) or 422 of the Code (or any other applicable law or
regulation, including the requirements of the NASD or an established stock
exchange), the Company shall obtain shareholder approval of any Plan amendment
in such a manner and to such a degree as required.

         (b)  EFFECT OF AMENDMENT OR TERMINATION.  Any such amendment or
termination of the Plan shall not affect Options or Stock Purchase Rights
already granted and such awards shall remain in full force and effect as if this
Plan had not been amended or terminated, unless mutually agreed otherwise
between the grantee and the Board, which agreement must be in writing and signed
by the grantee and the Company.

    16.  CONDITIONS UPON ISSUANCE OF SHARES.  Shares shall not be issued
pursuant to the exercise of an Option unless the exercise of such Option and the
issuance and delivery of such Shares pursuant thereto shall comply with all
relevant provisions of law, including, without limitation, the Securities Act of
1933, as amended, the Exchange Act, the rules and regulations promulgated
thereunder, and the requirements of any stock exchange upon which the Shares may
then be listed, and shall be further subject to the approval of counsel for the
Company with respect to such compliance.

    As a condition to the exercise of an Option, the Company may require the
person exercising such Option to represent and warrant at the time of any such
exercise that the Shares are being purchased only for investment and without any
present intention to sell or distribute such Shares if, in the opinion of
counsel for the Company, such a representation is required by any of the
aforementioned relevant provisions of law.

                                          11

<PAGE>


    17.  RESERVATION OF SHARES.  The Company, during the term of this Plan,
will at all times reserve and keep available such number of Shares as shall be
sufficient to satisfy the requirements of the Plan.

    The inability of the Company to obtain authority from any regulatory body
having jurisdiction, which authority is deemed by the Company's counsel to be
necessary to the lawful issuance and sale of any Shares hereunder, shall relieve
the Company of any liability in respect of the failure to issue or sell such
Shares as to which such requisite authority shall not have been obtained.

    18.  AGREEMENTS.  Options and Stock Purchase Rights shall be evidenced by
written agreements in such form as the Board shall approve from time to time.

    19.  SHAREHOLDER APPROVAL.  Continuance of the Plan shall be subject to
approval by the shareholders of the Company within twelve (12) months before or
after the date the Plan is adopted. Such shareholder approval shall be obtained
in the degree and manner required under applicable state and federal law.

    20.  INFORMATION TO OPTIONEE.  The Company shall provide to each Optionee,
during the period for which such Optionee has one or more Options outstanding,
copies of all annul reports and other information which are provided to all
shareholders of the Company. The Company shall not be required to provide such
information if the issuance of Options under the Plan is limited to key
employees whose duties in connection with the Company assure their access to
equivalent information.

                                          12



<PAGE>

                                                                    Exhibit 99.3




                           ARRIS PHARMACEUTICAL CORPORATION

                             EMPLOYEE STOCK PURCHASE PLAN

                         ADOPTED BY THE BOARD OCTOBER 1, 1993
                       APPROVED BY STOCKHOLDERS OCTOBER 5, 1993
                      AS AMENDED BY THE BOARD FEBRUARY 27, 1996
                        APPROVED BY STOCKHOLDERS JUNE 5, 1996


1.  PURPOSE.

    (a)  The purpose of the Employee Stock Purchase Plan (the "Plan") is to
provide a means by which employees of Arris Pharmaceutical Corporation, a
Delaware corporation (the "Company"), and its Affiliates, as defined in
subparagraph 1(b), which are designated as provided in subparagraph 2(b), may be
given an opportunity to purchase stock of the Company.

    (b)  The word "Affiliate" as used in the Plan means any parent corporation
or subsidiary corporation of the Company, as those terms are defined in
Sections 424(e) and (f), respectively, of the Internal Revenue Code of 1986, as
amended (the "Code").

    (c)  The Company, by means of the Plan, seeks to retain the services of its
employees, to secure and retain the services of new employees, and to provide
incentives for such persons to exert maximum efforts for the success of the
Company.

    (d)  The Company intends that the rights to purchase stock of the Company
granted under the Plan be considered options issued under an "employee stock
purchase plan" as that term is defined in Section 423(b) of the Code.

2.  ADMINISTRATION.

    (a)  The Plan shall be administered by the Board of Directors (the "Board")
of the Company unless and until the Board delegates administration to a
Committee, as provided in subparagraph 2(c).  Whether or not the Board has
delegated administration, the Board shall have the final power to determine all
questions of policy and expediency that may arise in the administration of the
Plan.

    (b)  The Board shall have the power, subject to, and within the limitations
of, the express provisions of the Plan:

         (i)  To determine when and how rights to purchase stock of the Company
shall be granted and the provisions of each offering of such rights (which need
not be identical).

         (ii) To designate from time to time which Affiliates of the Company
shall be eligible to participate in the Plan.

                                          1

<PAGE>

        (iii) To construe and interpret the Plan and rights granted under it,
and to establish, amend and revoke rules and regulations for its administration.
The Board, in the exercise of this power, may correct any defect, omission or
inconsistency in the Plan, in a manner and to the extent it shall deem necessary
or expedient to make the Plan fully effective.

         (iv) To amend the Plan as provided in paragraph 13.

         (v)  Generally, to exercise such powers and to perform such acts as
the Board deems necessary or expedient to promote the best interests of the
Company.

    (c)  The Board may delegate administration of the Plan to a Committee
composed of not fewer than two (2) members of the Board (the "Committee").  If
administration is delegated to a Committee, the Committee shall have, in
connection with the administration of the Plan, the powers theretofore possessed
by the Board, subject, however, to such resolutions, not inconsistent with the
provisions of the Plan, as may be adopted from time to time by the Board.  The
Board may abolish the Committee at any time and revest in the Board the
administration of the Plan.

3.  SHARES SUBJECT TO THE PLAN.

    (a)  Subject to the provisions of paragraph 12 relating to adjustments upon
changes in stock, the stock that may be sold pursuant to rights granted under
the Plan shall not exceed in the aggregate two hundred fifty thousand (250,000)
shares of the Company's common stock (the "Common Stock").  If any right granted
under the Plan shall for any reason terminate without having been exercised, the
Common Stock not purchased under such right shall again become available for the
Plan.

    (b)  The stock subject to the Plan may be unissued shares or reacquired
shares, bought on the market or otherwise.

4.  GRANT OF RIGHTS; OFFERING.

    The Board or the Committee may from time to time grant or provide for the
grant of rights to purchase Common Stock of the Company under the Plan to
eligible employees (an "Offering") on a date or dates (the "Offering Date(s)")
selected by the Board or the Committee.  Each Offering shall be in such form and
shall contain such terms and conditions as the Board or the Committee shall deem
appropriate.  The provisions of separate Offerings need not be identical, but
each Offering shall include (through incorporation of the provisions of this
Plan by reference in the Offering or otherwise) the substance of the provisions
contained in paragraphs 5 through 8, inclusive.

                                          2

<PAGE>

5.  ELIGIBILITY.

    (a)  Rights may be granted only to employees of the Company or, as the
Board or the Committee may designate as provided in subparagraph 2(b), to
employees of any Affiliate of the Company.  Except as provided in subparagraph
5(b), an employee of the Company or any Affiliate shall not be eligible to be
granted rights under the Plan, unless, on the Offering Date, such employee has
been in the employ of the Company or any Affiliate for such continuous period
preceding such grant as the Board or the Committee may require, but in no event
shall the required period of continuous employment be equal to or greater than
two (2) years.  In addition, unless otherwise determined by the Board or the
Committee and set forth in the terms of the applicable Offering, no employee of
the Company or any Affiliate shall be eligible to be granted rights under the
Plan, unless, on the Offering Date, such employee's customary employment with
the Company or such Affiliate is at least twenty (20) hours per week and at
least five (5) months per calendar year.

    (b)  The Board or the Committee may provide that each person who, during
the course of an Offering, first becomes an eligible employee of the Company or
designated Affiliate will, on a date or dates specified in the Offering which
coincides with the day on which such person becomes an eligible employee or
occurs thereafter, receive a right under that Offering, which right shall
thereafter be deemed to be a part of that Offering.  Such right shall have the
same characteristics as any rights originally granted under that Offering, as
described herein, except that:

         (i)  the date on which such right is granted shall be the "Offering
Date" of such right for all purposes, including determination of the exercise
price of such right;

         (ii) the Offering Period for such right shall begin on its Offering
Date and end coincident with the end of such Offering; and

         (iii)     the Board or the Committee may provide that if such person
first becomes an eligible employee within a specified period of time before the
end of the Offering Period for such Offering, he or she will not receive any
right under that Offering.

    (c)  No employee shall be eligible for the grant of any rights under the
Plan if, immediately after any such rights are granted, such employee owns stock
possessing five percent (5%) or more of the total combined voting power or value
of all classes of stock of the Company or of any Affiliate.  For purposes of
this subparagraph 5(c), the rules of Section 424(d) of the Code shall apply in
determining the stock ownership of any employee, and stock which such employee
may purchase under all outstanding rights and options shall be treated as stock
owned by such employee.

    (d)  An eligible employee may be granted rights under the Plan only if such
rights, together with any other rights granted under "employee stock purchase
plans" of the Company and any Affiliates, as specified by Section 423(b)(8) of
the Code, do not permit such employee's rights to purchase stock of the Company
or any Affiliate to accrue at a rate which exceeds

                                          3

<PAGE>

twenty-five thousand dollars ($25,000) of fair market value of such stock
(determined at the time such rights are granted) for each calendar year in which
such rights are outstanding at any time.

    (e)  Officers of the Company and any designated Affiliate shall be eligible
to participate in Offerings under the Plan, provided, however, that the Board
may provide in an Offering that certain employees who are highly compensated
employees within the meaning of Section 423(b)(4)(D) of the Code shall not be
eligible to participate.

6.  RIGHTS; PURCHASE PRICE.

    (a)  On each Offering Date, each eligible employee, pursuant to an Offering
made under the Plan, shall be granted the right to purchase up to the number of
shares of Common Stock of the Company purchasable with a percentage designated
by the Board or the Committee not exceeding fifteen percent (15%) of such
employee's Earnings (as defined in Section 7(a)) during the period which begins
on the Offering Date (or such later date as the Board or the Committee
determines for a particular Offering) and ends on the date stated in the
Offering, which date shall be no more than twenty-seven (27) months after the
Offering Date (the "Offering Period").  In connection with each Offering made
under this Plan, the Board or the Committee shall specify a maximum number of
shares which may be purchased by any employee as well as a maximum aggregate
number of shares which may be purchased by all eligible employees pursuant to
such Offering.  In addition, in connection with each Offering which contains
more than one Purchase Date (as defined in the Offering), the Board or the
Committee may specify a maximum aggregate number of shares which may be
purchased by all eligible employees on any given Purchase Date under the
Offering.  If the aggregate purchase of shares upon exercise of rights granted
under the Offering would exceed any such maximum aggregate number, the Board or
the Committee shall make a pro rata allocation of the shares available in as
nearly a uniform manner as shall be practicable and as it shall deem to be
equitable.

    (b)  The purchase price of stock acquired pursuant to rights granted under
the Plan shall be not less than the lesser of:

         (i)  an amount equal to eighty-five percent (85%) of the fair market
value of the stock on the Offering Date; or

         (ii) an amount equal to eighty-five percent (85%) of the fair market
value of the stock on the Purchase Date.

7.  PARTICIPATION; WITHDRAWAL; TERMINATION.

    (a)  An eligible employee may become a participant in an Offering by
delivering a participation agreement to the Company within the time specified in
the Offering, in such form as the Company provides.  Each such agreement shall
authorize payroll deductions of up to the maximum percentage specified by the
Board or the Committee of such employee's Earnings during the Offering Period.
"Earnings" is defined as the total compensation paid to an employee, including
all salary, wages (including amounts elected to be deferred by the

                                          4

<PAGE>

employee, that would otherwise have been paid, under any cash or deferred
arrangement established by the Company), overtime pay, commissions, bonuses, and
other remuneration paid directly to the employee, but excluding profit sharing,
the cost of employee benefits paid for by the Company, education or tuition
reimbursements, imputed income arising under any Company group insurance or
benefit program, traveling expenses, business and moving expense reimbursements,
income received in connection with stock options, contributions made by the
Company under any employee benefit plan, and similar items of compensation.  The
payroll deductions made for each participant shall be credited to an account for
such participant under the Plan and shall be deposited with the general funds of
the Company.  A participant may reduce (including to zero), increase or begin
such payroll deductions after the beginning of any Purchase Period only as
provided for in the Offering.

    (b)  At any time during an Offering Period a participant may terminate his
or her payroll deductions under the Plan and withdraw from the Offering by
delivering to the Company a notice of withdrawal in such form as the Company
provides.  Such withdrawal may be elected at any time prior to the end of the
Offering Period except as provided by the Board or the Committee in the
Offering.  Upon such withdrawal from the Offering by a participant, the Company
shall distribute to such participant all of his or her accumulated payroll
deductions (reduced to the extent, if any, such deductions have been used to
acquire stock for the participant) under the Offering, without interest, and
such participant's interest in that Offering shall be automatically terminated.
A participant's withdrawal from an Offering will have no effect upon such
participant's eligibility to participate in any other Offerings under the Plan
but such participant will be required to deliver a new participation agreement
in order to participate in subsequent Offerings under the Plan.

    (c)  Rights granted pursuant to any Offering under the Plan shall terminate
immediately upon cessation of any participating employee's employment with the
Company and any designated Affiliate, for any reason, and the Company shall
distribute to such terminated employee all of his or her accumulated payroll
deductions (reduced to the extent, if any, such deductions have been used to
acquire stock for the terminated employee), under the Offering, without
interest.

    (d)  Rights granted under the Plan shall not be transferable, and, except
as provided in Section 14, shall be exercisable only by the person to whom such
rights are granted.

8.  EXERCISE.

    (a)  On each purchase date, as defined in the relevant Offering (a
"Purchase Date"), each participant's accumulated payroll deductions and other
additional payments specifically provided for in the Offering (without any
increase for interest) will be applied to the purchase of whole shares of stock
of the Company, up to the maximum number of shares permitted pursuant to the
terms of the Plan and the applicable Offering, at the purchase price specified
in the Offering.  No fractional shares shall be issued upon the exercise of
rights granted under the Plan.  The amount, if any, of accumulated payroll
deductions remaining in each participant's account after the purchase of shares
which is less than the amount required to purchase one share

                                          5

<PAGE>

of stock on the final Purchase Date of an Offering shall be held in each such
participant's account for the purchase of shares under the next Offering under
the Plan, unless such participant withdraws from such next Offering, as provided
in subparagraph 7(b), or is no longer eligible to be granted rights under the
Plan, as provided in paragraph 5, in which case such amount shall be distributed
to the participant after the final Purchase Date of the Offering, without
interest.  The amount, if any, of accumulated payroll deductions remaining in
any participant's account after the purchase of shares which is equal to the
amount required to purchase whole shares of stock on the final Purchase Date of
an Offering shall be distributed in full to the participant after such Purchase
Date, without interest.

    (b)  No rights granted under the Plan may be exercised to any extent unless
the Plan (including rights granted thereunder) is covered by an effective
registration statement pursuant to the Securities Act of 1933, as amended (the
"Securities Act").  If on a Purchase Date of any Offering hereunder the Plan is
not so registered, no rights granted under the Plan or any Offering shall be
exercised on said Purchase Date and the Purchase Date shall be delayed until the
Plan is subject to such an effective registration statement, except that the
Purchase Date shall not be delayed more than two (2) months and the Purchase
Date shall in no event be more than twenty-seven (27) months from the Offering
Date.  If on the Purchase Date of any Offering hereunder, as delayed to the
maximum extent permissible, the Plan is not registered, no rights granted under
the Plan or any Offering shall be exercised and all payroll deductions
accumulated during the Offering Period (reduced to the extent, if any, such
deductions have been used to acquire stock) shall be distributed to the
participants, without interest.

9.  COVENANTS OF THE COMPANY.

    (a)  During the terms of the rights granted under the Plan, the Company
shall keep available at all times the number of shares of stock required to
satisfy such rights.

    (b)  The Company shall seek to obtain from each regulatory commission or
agency having jurisdiction over the Plan such authority as may be required to
issue and sell shares of stock upon exercise of the rights granted under the
Plan.  If, after reasonable efforts, the Company is unable to obtain from any
such regulatory commission or agency the authority which counsel for the Company
deems necessary for the lawful issuance and sale of stock under the Plan, the
Company shall be relieved from any liability for failure to issue and sell stock
upon exercise of such rights unless and until such authority is obtained.

10. USE OF PROCEEDS FROM STOCK.

    Proceeds from the sale of stock pursuant to rights granted under the Plan
shall constitute general funds of the Company.



                                          6


<PAGE>

11. RIGHTS AS A STOCKHOLDER.

    A participant shall not be deemed to be the holder of, or to have any of
the rights of a holder with respect to, any shares subject to rights granted
under the Plan unless and until the participant's shareholdings acquired upon
exercise of rights hereunder are recorded in the books of the Company.

12. ADJUSTMENTS UPON CHANGES IN STOCK.

    (a)  If any change is made in the stock subject to the Plan, or subject to
any rights granted under the Plan (through merger, consolidation,
reorganization, recapitalization, stock dividend, dividend in property other
than cash, stock split, liquidating dividend, combination of shares, exchange of
shares, change in corporate structure or otherwise), the Plan and outstanding
rights will be appropriately adjusted in the class(es) and maximum number of
shares subject to the Plan and the class(es) and number of shares and price per
share of stock subject to outstanding rights.

    (b)  In the event of:  (1) a dissolution or liquidation of the Company;
(2) a merger or consolidation in which the Company is not the surviving
corporation; (3) a reverse merger in which the Company is the surviving
corporation but the shares of the Company's Common Stock outstanding immediately
preceding the merger are converted by virtue of the merger into other property,
whether in the form of securities, cash or otherwise; or (4) any other capital
reorganization in which more than fifty percent (50%) of the shares of the
Company entitled to vote are exchanged, then, as determined by the Board in its
sole discretion (i) any surviving corporation may assume outstanding rights or
substitute similar rights for those under the Plan, (ii) such rights may
continue in full force and effect, or (iii) participants' accumulated payroll
deductions may be used to purchase Common Stock immediately prior to the
transaction described above and the participants' rights under the ongoing
Offering terminated.

13. AMENDMENT OF THE PLAN.

    (a)  The Board at any time, and from time to time, may amend the Plan.
However, except as provided in paragraph 12 relating to adjustments upon changes
in stock, no amendment shall be effective unless approved by the stockholders of
the Company within twelve (12) months before or after the adoption of the
amendment, where the amendment will:

         (i)  Increase the number of shares reserved for rights under the Plan;

         (ii) Modify the provisions as to eligibility for participation in the
    Plan (to the extent such modification requires stockholder approval in
    order for the Plan to obtain employee stock purchase plan treatment under
    Section 423 of the Code or to comply with the requirements of Rule 16b-3
    promulgated under the Securities Exchange Act of 1934, as amended ("Rule
    16b-3")); or

                                          7


<PAGE>

         (iii)     Modify the Plan in any other way if such modification
    requires stockholder approval in order for the Plan to obtain employee
    stock purchase plan treatment under Section 423 of the Code or to comply
    with the requirements of Rule 16b-3.

It is expressly contemplated that the Board may amend the Plan in any respect
the Board deems necessary or advisable to provide eligible employees with the
maximum benefits provided or to be provided under the provisions of the Code and
the regulations promulgated thereunder relating to employee stock purchase plans
and/or to bring the Plan and/or rights granted under it into compliance
therewith.

    (b)  Rights and obligations under any rights granted before amendment of
the Plan shall not be altered or impaired by any amendment of the Plan, except
with the consent of the person to whom such rights were granted or except as
necessary to comply with any laws or governmental regulation.

14. DESIGNATION OF BENEFICIARY.

    (a)  A participant may file a written designation of a beneficiary who is
to receive any shares and cash, if any, from the participant's account under the
Plan in the event of such participant's death subsequent to the end of an
Offering but prior to delivery to him of such shares and cash.  In addition, a
participant may file a written designation of a beneficiary who is to receive
any cash from the participant's account under the Plan in the event of such
participant's death during an Offering Period.

    (b)  Such designation of beneficiary may be changed by the participant at
any time by written notice.  In the event of the death of a participant and in
the absence of a beneficiary validly designated under the Plan who is living at
the time of such participant's death, the Company shall deliver such shares
and/or cash to the executor or administrator of the estate of the participant,
or if no such executor or administrator has been appointed (to the knowledge of
the Company), the Company, in its discretion, may deliver such shares and/or
cash to the spouse or to any one or more dependents or relatives of the
participant, or if no spouse, dependent or relative is known to the Company,
then to such other person as the Company may designate.

15. TERMINATION OR SUSPENSION OF THE PLAN.

    (a)  The Board may suspend or terminate the Plan at any time.  Unless
sooner terminated, the Plan shall terminate on December 31, 2002.  No rights may
be granted under the Plan while the Plan is suspended or after it is terminated.

    (b)  Rights and obligations under any rights granted while the Plan is in
effect shall not be altered or impaired by suspension or termination of the
Plan, except with the consent of the person to whom such rights were granted or
except as necessary to comply with any laws or governmental regulation.

                                          8

<PAGE>

16. EFFECTIVE DATE OF PLAN.

    The Plan shall become effective as determined by the Board, but no rights
granted under the Plan shall be exercised unless and until the Plan has been
approved by the stockholders of the Company.


                                          9




<PAGE>

                                                                    Exhibit 99.4




                           ARRIS PHARMACEUTICAL CORPORATION

                        EMPLOYEE STOCK PURCHASE PLAN OFFERING

                  FOR OFFERINGS BEGINNING ON OR AFTER AUGUST 1, 1996


1.  GRANT; OFFERING DATE.

    The Board of Directors of Arris Pharmaceutical Corporation, a Delaware
corporation (the "Company"), pursuant to the Company's Employee Stock Purchase
Plan (the "Plan"), hereby authorizes the grant of rights to purchase shares of
the common stock of the Company ("Common Stock") to all Eligible Employees (an
"Offering").  The first Offering hereunder shall begin August 1, 1996 and end on
July 31, 1998, unless terminated sooner as herein provided (the "1996
Offering").  Thereafter Offerings shall begin on August 1, 1998 and on each
subsequent second anniversary of the most recent Offering Date (the first day of
an Offering is that Offering's "Offering Date"); PROVIDED, HOWEVER, that if on
any Purchase Date (as defined in Section 6 below) the fair market value of the
Company's Common Stock is less than it was on the Offering Date for that
Offering, the day after such Purchase Date (I.E., February 1 or August 1) shall
become the next Offering Date and the Offering that would otherwise have
continued in effect shall immediately terminate.  Each Offering after the 1996
Offering shall end on the day prior to the second anniversary of its Offering
Date unless sooner terminated as provided above.

    Prior to the commencement of any Offering, the Board of Directors or the
Compensation Committee may change any or all terms of such Offering and any
subsequent Offerings.  The granting of rights pursuant to each Offering
hereunder shall occur on each respective Offering Date unless, prior to such
date (a) the Board of Directors or the Compensation Committee determines that
such Offering shall not occur, or (b) no shares remain available for issuance
under the Plan in connection with the Offering.

2.  ELIGIBLE EMPLOYEES.

    (a)  All employees of the Company and each of its Affiliates (as defined in
the Plan) incorporated in the United States shall be granted rights to purchase
Common Stock under each Offering on the Offering Date of such Offering, provided
that each such employee otherwise meets the employment requirements of
subparagraph 5(a) of the Plan and has been continuously employed by the Company
for at least three months (an "Eligible Employee").  Notwithstanding the
foregoing, no employee who is disqualified by subparagraph 5(c) or 5(d) of the
Plan shall be an Eligible Employee or be granted rights under an Offering.

    (b)  Notwithstanding the foregoing, each person who first becomes an
Eligible Employee after an Offering Date will on the next February 1st or
August 1st during that Offering receive a right under such Offering, which right
shall thereafter be deemed to be a part

                                          1
<PAGE>

of the Offering.  Such right shall have the same characteristics as any rights
originally granted under the Offering, except that:

         (1)  the date on which such right is granted shall be the "Offering
Date" of such right for all purposes, including determination of the exercise
price of such right; and


         (2)  the Offering for such right shall begin on its Offering Date and
end coincident with the end of the ongoing Offering.

3.  RIGHTS.

    (a)  Subject to the limitations contained herein and in the Plan, on each
Offering Date each Eligible Employee shall be granted the right to purchase the
number of shares of Common Stock purchasable with up to ten percent (10%) of
such employee's Earnings (as defined in the Plan) paid during such Offering;
PROVIDED, HOWEVER, that no employee may purchase Common Stock in a particular
year with more than ten percent (10%) of such employee's Earnings in such year
under all ongoing Offerings under the Plan and all other Company plans intended
to qualify as "employee stock purchase plans" under Section 423 of the Internal
Revenue Code of 1986, as amended.  Notwithstanding the foregoing, the maximum
number of shares of Common Stock an Eligible Employee may purchase on any
Purchase Date (as defined in Section 6) in an Offering shall be the number of
shares determined by dividing $12,500 by the fair market value of a share of the
Common Stock on the Offering Date for such Offering.

    (b)  The maximum aggregate number of shares available to be purchased by
all Eligible Employees under an Offering shall be one hundred thousand (100,000)
shares of Common Stock, or, if less, the number of shares remaining available
under the Plan on the Offering Date.  The maximum aggregate number of shares
available to be purchased by Eligible Employees on any Purchase Date (as defined
in Section 6) under an Offering shall be the lesser of (i) fifty thousand
(50,000) shares of Common Stock, (ii) one hundred thousand (100,000) shares of
Common Stock less any shares of Common Stock previously purchased on any
Purchase Date during the Offering, or (iii) the number of shares remaining
available under the Plan.  If the aggregate purchase of shares of Common Stock
upon exercise of rights granted under the Offering would exceed the maximum
aggregate number of shares available, the Board shall make a pro rata allocation
of the shares available in a uniform and equitable manner.

4.  PURCHASE PRICE.

    The purchase price of the Common Stock shall be the lesser of eighty-five
percent (85%) of the fair market value of the Common Stock on the Offering Date
or eighty-five percent (85%) of the fair market value of the Common Stock on the
Purchase Date, in each case rounded up to the nearest cent per share.

                                          2
<PAGE>

5.  PARTICIPATION.

    An Eligible Employee may elect to participate in an Offering at the
beginning of the Offering or any February 1st or August 1st during the Offering.
An Eligible Employee shall become a participant in an Offering by delivering an
agreement authorizing payroll deductions.  Such deductions may be in whole
percentages only, with a minimum percentage of one percent (1%), and a
participant may not make additional payments into his or her account.  The
agreement shall be in such form as the Company provides, and must be delivered
to the Company before the Offering Date or (February 1st or August 1st during an
Offering) to be effective for the remaining portion of that Offering, unless a
later time for filing the enrollment form is set by the Board for all Eligible
Employees with respect to a given Offering.  A participant may not increase or
reduce his or her participation percentage during the course of an Offering
except on each February 1st and August 1st.  A participant may withdraw from an
Offering and receive his or her accumulated payroll deductions (reduced to the
extent, if any, such deductions have been used to acquire stock for the
participant) from the Offering, without interest, at any time prior to the end
of the Offering Period of the Offering by delivering a withdrawal notice to the
Company in such form as the Company provides.

6.  EXERCISE.

    Subject to the limitations contained herein, on each Purchase Date, each
participant's accumulated payroll deductions (without any increase for interest)
shall be applied to the purchase of whole shares of Common Stock, up to the
maximum number of shares permitted under the Plan and the Offering.  "Purchase
Date" shall be defined as each January 31st and July 31st (I.E., the first
Purchase Date of the 1996 Offering shall be January 31, 1997 and the next
Purchase Date shall be July 31, 1997.)

7.  NOTICES AND AGREEMENTS.

    Any notices or agreements provided for in an Offering or the Plan shall be
given in writing, in a form provided by the Company, and unless specifically
provided for in the Plan or this Offering shall be deemed effectively given upon
receipt or, in the case of notices and agreements delivered by the Company,
five (5) days after deposit in the United States mail, postage prepaid.

8.  OFFERING SUBJECT TO PLAN.

    Each Offering is subject to all the provisions of the Plan, and its
provisions are hereby made a part of the Offering, and is further subject to all
interpretations, amendments, rules and regulations which may from time to time
be promulgated and adopted pursuant to the Plan.  In the event of any conflict
between the provisions of an Offering and those of the Plan (including
interpretations, amendments, rules and regulations which may from time to time
be promulgated and adopted pursuant to the Plan), the provisions of the Plan
shall control.

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