ARRIS PHARMACEUTICAL CORP/DE/
10-Q, 1996-08-13
PHARMACEUTICAL PREPARATIONS
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                                UNITED STATES            
                     SECURITIES AND EXCHANGE  COMMISSION 
                          WASHINGTON, D.C.   20549      
 
                     -----------------------------------

                                  FORM 10-Q              

[ X ]    QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE 
         SECURITIES EXCHANGE ACT OF 1934

                 For the quarterly period ended June 30, 1996

                                    OR

[    ]   TRANSITION REPORTS PURSUANT TO SECTION 13 OR 15(D) OF THE 
         SECURITIES EXCHANGE ACT OF 1934

For the transition period from----------------------to-----------------------.

                       Commission File Number: 0-22788

                       ARRIS PHARMACEUTICAL CORPORATION
            (Exact name of registrant as specified in its charter)

DELAWARE                                                              22-2969941
- --------                                                              ----------
(State or other jurisdiction of                (IRS Employer Identification No.)
incorporation or  organization)

                         385 OYSTER POINT BOULEVARD              
                    SOUTH SAN FRANCISCO, CALIFORNIA 94080        
                   (Address of principal executive offices)      

                               (415) 829-1000                    
             (Registrant's telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports 
required by Section 13 or 15(d) of the Securities Exchange Act of 1934 during 
the preceding 12 months (or for such shorter period that the registrant was 
required to file such reports), and (2) has been subject to such filing 
requirements for the past 90 days.  [x] Yes  [  ] No 

The number of outstanding shares of the registrant's Common Stock, $0.001 par 
value, was 14,052,905 as of July 31, 1996. 

                                      1

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                       ARRIS PHARMACEUTICAL CORPORATION

                                    INDEX


                                                                           PAGE
                                                                           ----
PART I:  FINANCIAL INFORMATION
- ------------------------------
ITEM 1.  Financial Statements (unaudited) *

         Consolidated Balance Sheets - June 30, 1996 and December 31, 1995... 3

         Consolidated   Statements of Operations - Three and six months
                        ended June 30, 1996 and 1995 ........................ 4

         Consolidated Statements of Cash Flows - Six months ended
                        June 30, 1996 and 1995 .............................. 5

         Notes to Consolidated Financial Statements - June 30, 1996 ......... 6

ITEM 2.  Management's Discussion and Analysis of Financial
                        Condition and Results of Operations ................. 9

PART II:  OTHER INFORMATION..................................................14
- ---------------------------

ITEM 1.  Legal Proceedings
ITEM 2.  Changes in Securities
ITEM 3.  Defaults Upon Senior Securities
ITEM 4.  Submission of Matters to a Vote of Security Holders
ITEM 5.  Other Information
ITEM 6.  Exhibits and Reports on Form 8-K

SIGNATURES...................................................................16


*  The financial information should be read in conjunction with the 
consolidated financial statements and notes thereto included in the Company's 
Report on Form 10-K for the year ended December 31, 1995, filed on March 14, 
1996.

                                      2

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                       ARRIS PHARMACEUTICAL CORPORATION

PART 1:   FINANCIAL INFORMATION
- -------------------------------

ITEM 1.  FINANCIAL STATEMENTS

                         CONSOLIDATED BALANCE SHEETS         
                                 (unaudited)                 

                                                           JUNE 30, DECEMBER 31,
                                                             1996      1995     
                                                           -------- ------------
ASSETS                                                         (IN THOUSANDS)   
Current assets:
 Cash and cash equivalents                                   $ 10,421  $ 21,706
 Short-term marketable investments                             39,414     9,399
 Prepaid expenses and other current assets                      2,414       798
                                                             --------  --------
    Total current assets                                       52,249    31,903

Marketable investments                                         18,808       -- 
Property and equipment, net                                     8,004     7,423
Other assets                                                      869       967
                                                             --------  --------
    TOTAL ASSETS                                             $ 79,930  $ 40,293
                                                             --------  --------
                                                             --------  --------
LIABILITIES AND STOCKHOLDERS' EQUITY 
Current liabilities:
 Accounts payable                                             $   838  $    872
 Accrued compensation                                           1,834     1,718
 Other accrued liabilities                                      1,473     2,651
 Current portion of deferred revenue                            9,706     8,585
 Current portion of capital lease and debt obligations          2,618     2,699
                                                             --------  --------
    Total current liabilities                                  16,469    16,525

Deferred revenue, net of current portion                        4,250     5,472
Capital lease and debt obligations, net of current portion      4,342     3,263
Convertible acquisition liability                               6,185     6,185
Minority interest payable                                       1,570     1,570

Stockholders' equity:
 Preferred stock, $.001 par value; 10,000,000 shares authorized,
    none issued or outstanding                                    --        -- 
Common stock, $.001 par value; 30,000,000 shares authorized,
 14,000,899 shares and 10,169,076 shares issued and outstanding 
 at June 30, 1996 and December 31, 1995, respectively         107,216    64,389
Note receivable from officer                                     (200)     (200)
Deferred compensation                                             --        (35)
Accumulated deficit                                           (59,902)  (56,876)
                                                             --------  --------
    Total stockholders' equity                                 47,114     7,278
                                                             --------  --------
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                   $ 79,930  $ 40,293
                                                             --------  --------
                                                             --------  --------

          See accompanying notes to consolidated financial statements.

                                       3


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                       ARRIS PHARMACEUTICAL CORPORATION

                    CONSOLIDATED STATEMENTS OF OPERATIONS
                                  (unaudited)                    



                                           THREE MONTHS ENDED   SIX MONTHS ENDED
                                                JUNE 30,            JUNE 30,    
                                           -------------------------------------
                                              1996    1995     1996     1995 
                                             ------  ------   ------   ------
                                        (IN THOUSANDS, EXCEPT PER SHARE AMOUNTS)
Revenues                                    $ 5,990  $3,948  $11,034  $ 7,821

Operating expenses:
 Research and development                     6,867   3,627   12,511    7,195
 General and administrative                   1,385   1,050    2,590    2,139
                                            -------  ------  -------  -------
    Total operating expenses                  8,252   4,677   15,101    9,334
                                            -------  ------  -------  -------
Operating loss                               (2,262)   (729)  (4,067)  (1,513)
Interest income                                 962     323    1,319      642
Interest expense                               (163)    (55)    (278)    (125)
                                            -------  ------  -------  -------
Net loss                                    $(1,463) $ (461) $(3,026)  $ (996)
                                            -------  ------  -------  -------
                                            -------  ------  -------  -------
Net loss per share                          $ (0.11) $(0.05) $ (0.25)  $(0.11)
                                            -------  ------  -------  -------
                                            -------  ------  -------  -------
Shares used in computing net loss per share  13,870   8,691   12,137    8,681
                                            -------  ------  -------  -------
                                            -------  ------  -------  -------

          See accompanying notes to consolidated financial statements.


                                      4

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                       ARRIS PHARMACEUTICAL CORPORATION

                     CONSOLIDATED STATEMENTS OF CASH FLOWS
                                  (unaudited)

                                                             SIX MONTHS ENDED
                                                                 JUNE 30,    
                                                            -----------------
                                                              1996      1995 
                                                            --------   ------
                                                              (IN THOUSANDS) 
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss                                                    $ (3,026)  $  (996)
Adjustments to reconcile net loss to net cash and
  cash equivalents used in operating activities:
   Depreciation and amortization                               2,021     1,183
   Stock grants issuable to employees                            --         37
   Loss on fixed assets                                          182        50
   Changes in assets and liabilities:
     Prepaid expenses and other current assets                (1,616)       17
     Other assets                                                 98       (12)
     Accounts payable, accrued liabilities and 
       deferred revenue                                       (1,197)   (4,138)
                                                            --------   -------
Net cash and cash equivalents used in operating activities    (3,538)   (3,859)
                                                            --------   -------

CASH FLOWS FROM INVESTING ACTIVITIES:
Available-for-sale securities:
  Purchases                                                   (9,973)   (8,808)
  Maturities                                                     --      7,155
Purchase of held-to-maturity security
  Purchases                                                  (67,071)   (3,506)
  Maturities                                                  28,221       -- 
Expenditures for property and equipment                       (2,749)   (1,733)
                                                            --------   -------
Net cash and cash equivalents used in investing activities   (51,572)   (6,892)
                                                            --------   -------
CASH FLOWS FROM FINANCING ACTIVITIES:
Net proceeds from issuance of common stock                    42,827       175
Proceeds from note payable and lease financing                 2,886     1,569
Principal payments on note payable and capital leases         (1,888)     (981)
                                                            --------   -------
Net cash and cash equivalents provided by 
  (used in) financing activities                              43,825       763
                                                            --------   -------
Net decrease in cash and cash equivalents                    (11,285)   (9,988)
Cash and cash equivalents, beginning of period                21,706    17,165
                                                            --------   -------
Cash and cash equivalents, end of period                    $ 10,421   $ 7,177
                                                            --------   -------
                                                            --------   -------


See accompanying notes to consolidated financial statements. 

                                      5

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                        ARRIS PHARMACEUTICAL CORPORATION 

                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                   JUNE 30,1996
                                    (unaudited)


1.  ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES


ORGANIZATION

Arris Pharmaceutical Corporation, a Delaware corporation ("Arris" or the 
"Company") uses an integrated drug discovery approach combining 
structure-based drug design, combinatorial chemistry and its proprietary 
Delta Technology to discover and develop a number of diverse synthetic small 
molecule therapeutics for commercially important disease categories where 
existing therapies have significant limitations.  Arris' product development 
programs include: (1) protease-based discovery programs targeting the 
inhibition of enzymes implicated in inflammatory and other diseases, and (2) 
receptor-based discovery programs including those designed to discover small 
molecule drugs that mimic important therapeutic proteins that are already 
successful products.

The consolidated financial statements include the accounts of the Company, 
its wholly-owned subsidiary, Arris Protease, Inc., and its 50%-owned 
subsidiary, Arris Pharmaceuticals Canada, Inc. ("Arris Canada") which have 
been consolidated based on the Company's ability to demonstrate effective 
control over these entities.  All significant intercompany accounts and 
transactions have been eliminated (See Subsequent Event).

BASIS OF PRESENTATION

The unaudited consolidated financial statements included herein have been 
prepared by the Company according to the rules and regulations of the 
Securities and Exchange Commission.  Certain information and footnote 
disclosures normally included in complete financial statements prepared in 
accordance with generally accepted accounting principles have been condensed 
or omitted pursuant to such rules and regulations.  The financial statements 
reflect, in the opinion of management, all adjustments (which include only 
normal recurring adjustments) necessary to state fairly the financial 
position and results of operations as of and for the periods indicated.  The 
results of operations for the three and six month periods ended June 30, 1996 
are not necessarily indicative of the results to be expected for subsequent 
quarters or the full fiscal year. 

These financial statements should be read in conjunction with the audited 
financial statements and the notes thereto included in the Company's 1995 
Annual Report on Form 10-K filed with the Securities and Exchange Commission.


                                      6

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                        ARRIS PHARMACEUTICAL CORPORATION 

             NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)


2.  CASH AND CASH EQUIVALENTS AND MARKETABLE SECURITIES

The Company considers all highly liquid investments with maturities of three 
months or less at the date of purchase to be cash equivalents.  Marketable 
securities consist of U.S. treasury and agency securities, municipal 
obligations and high-grade corporate obligations.  Amortization of premiums 
and accretion of discounts to maturity are included in interest income.

SECURITIES HELD-TO-MATURITY:   Management determines the appropriate 
classification of debt securities at the time of purchase and reevaluates 
such designation as of each balance sheet date. Debt securities are 
classified as held-to-maturity  when the Company has the positive intent and 
ability to hold the securities to maturity. Held-to-maturity securities are 
stated at amortized cost.

The following is a summary of held-to-maturity debt securities at June 30, 
1996 and December 31, 1995:

                                        HELD-TO-MATURITY SECURITIES           
                             -------------------------------------------------
                                           GROSS         GROSS       ESTIMATED
                                         UNREALIZED    UNREALIZED      FAIR   
                              COST         GAINS         LOSSES        VALUE  
                             -------     ----------    ----------    ---------
                                               (IN THOUSANDS)
Balances at June 30, 1996
   U.S. treasury securities  $19,187     $     --        $  (9)       $19,178
   U.S. agency securities      8,414           --          (12)         8,402
   U.S. corporate securities  20,647           --          (16)        20,631
                             -------     ----------      ------       -------
                             $48,248     $     --        $ (37)       $48,211
                             -------     ----------      ------       -------
                             -------     ----------      ------       -------

Balances at December 31, 1995
   U.S. treasury securities  $ 5,015     $     --        $(101)       $ 4,914
   U.S. agency securities      7,392           --          (23)         7,369
   U.S. corporate securities  11,487           --          (14)        11,473
                             -------     ----------      ------       -------
                             $23,894     $     --        $(138)       $23,756
                             -------     ----------      ------       -------
                             -------     ----------      ------       -------

At June 30, 1996, $39,414,000 were in short-term marketable investments and 
$8,834,000 were considered non-current marketable investments.  At December 
31, 1995, $14,495,000 were included in cash equivalents, of the total amount 
of cash and cash equivalents of $21,706,000 and $9,399,000 were in short-term 
marketable investments.  As of June 30, 1996, the average remaining portfolio 
duration of held-to-maturity securities was approximately nine months.  

SECURITIES AVAILABLE-FOR-SALE:  Debt securities not classified as 
held-to-maturity are classified as available-for-sale. Available-for-sale 
securities are stated at fair market value, with the unrealized gains and 
losses included in accumulated deficit.   The Company had $9,974,000 in


                                      7

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                        ARRIS PHARMACEUTICAL CORPORATION 

             NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)


U.S. treasury notes at June 30, 1996, and the fair value of these securities 
approximates cost.  These securities are included in non-current marketable 
investments at June 30, 1996.  The Company had no securities classified as 
available-for-sale at December 31, 1995.

3.  SUBSEQUENT EVENT

On July 9, 1996 the Minority Interest Investors in Arris Canada exercised 
their right to exchange their interest in Arris Canada for 161,418 shares of 
the Company's common stock.  Upon conversion of their shares, Arris Canada 
will become a wholly owned subsidiary of the Company.  The fair value of the 
shares issued to the minority interest investors exceeds the book value of 
the minority interest in Arris Canada by $230,000. This amount will be 
expensed in the third quarter of 1996. 



                                      8

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                        ARRIS PHARMACEUTICAL CORPORATION 

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                      AND RESULTS OF OPERATIONS


THIS QUARTERLY REPORT ON FORM 10-Q CONTAINS, IN ADDITION TO HISTORICAL 
INFORMATION, FORWARD-LOOKING STATEMENTS THAT INVOLVE RISKS AND UNCERTAINTIES. 
THE COMPANY'S ACTUAL RESULTS COULD DIFFER SIGNIFICANTLY FROM THE RESULTS 
DISCUSSED IN THE FORWARD-LOOKING STATEMENTS.  FACTORS THAT COULD CAUSE OR 
CONTRIBUTE TO SUCH DIFFERENCES INCLUDE, BUT ARE NOT LIMITED TO THOSE DISCUSSED 
BELOW AS WELL AS THOSE DISCUSSED IN THE COMPANY'S PROPECTUS DATED MARCH 22, 
1996.

OVERVIEW

Since its inception in April 1989, the Company has devoted substantially all 
of its resources to its research and development programs.  To date, the 
Company's only source of revenue has been its corporate collaborations with 
Pharmacia & Upjohn, Inc. and its predecessors ("PNU"), Amgen, Inc. ("Amgen"), 
Bayer AG ("Bayer") and a new collaboration with SmithKline Beecham ("SB").  
Its collaborations have taken a variety of forms including in each case 
certain of the following elements:  payments to the Company of an up-front 
fee, purchase of the Company's common stock (PNU human growth hormone 
collaboration only), research funding payments, milestone payments, if and 
when received and royalties upon the sale of any resulting products. Where 
appropriate, the up-front fees have been recorded as deferred revenue until 
earned.

In June 1996, the Company announced a new collaboration agreement with SB to 
explore the application of the Company's proprietary Delta technology to 
intracellular antiviral protease targets.  The agreement provides for a 
license fee and an intial proof-of-concept phase. Assuming success in the 
proof-of-concept phase, the agreement then provides for a research and 
development collaboration, with potential milestone payments and royalties 
upon the sale of any resulting products. 

The Company has not been profitable since inception and expects to incur 
substantial losses for at least the next several years, primarily due to the 
cost of its research and development programs, including preclinical studies 
and human clinical trials.  The Company expects that losses will fluctuate 
from quarter to quarter, that such fluctuations may be substantial, and that 
results from prior quarters may not be indicative of future operating 
results.  As of June 30, 1996, the Company's accumulated deficit was 
approximately $59.9 million.

RESULTS OF OPERATIONS

The Company's revenues increased to $6.0 million and $11.0 million for the 
three- and six-month periods ended June 30, 1996, respectively, as compared 
to $3.9 million and $7.8 million, respectively for periods in 1995. These 
increases for 1996 were primarily due to:  (i) the full effect in the 1996 
periods of the high throughput screening collaboration with PNU initiated in 
April 1995, (ii) commencement in August 1995 of the collaboration with PNU 
for the discovery and development of oral antithrombotics, (iii) commencement 
in March 1996 of the combinatorial chemistry collaboration with PNU and (iv) 
the commencement in June of 1996 of the collaboration with SB, described 
above, to apply Delta technology to certain viral proteases.


                                      9

<PAGE>

                        ARRIS PHARMACEUTICAL CORPORATION 

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                      AND RESULTS OF OPERATIONS (CONTINUED)


Revenues in the second half of 1996, are expected to be approximately the 
same as that of the first half of 1996.

Research and development expenses increased to $6.9 million and $12.5 million 
for the three- and six-month period ended June 30, 1996 respectively, from 
$3.6 and $7.2 million in the comparable periods in 1995.  This increase was 
primarily due to (i) the expansion of the Company's research efforts in new 
and existing programs and the expenses of programs and facilities added as 
part of the December 22, 1995 acquisition of Khepri Pharmaceuticals, Inc. 
("Khepri"), (ii) ramp up costs associated with the additional collaborations 
commencing in the first half of 1996, and (iii) certain severance costs.  The 
Company expects its research and development costs to increase during the 
remainder of 1996 and into 1997 due to expansion of its research programs and 
the conduct of additional preclinical studies and clinical trials. 

The Company's general and administrative expenses increased to $1.4 million 
and $2.6 million for the three-and six-month periods ended June 30, 1996 from 
$1.1 and $2.1 million in the comparable periods in 1995. General and 
administrative expenses as a percentage of total expenses has decreased in 
the six months period to 17% in 1996 from 23% in 1995.  The increase in 
expense was primarily due to the acquisition of Khepri, and the addition of 
general and administrative personnel in support of the Company's expanded 
research and development efforts.  The Company expects its general and 
administrative costs to increase for the remainder of 1996 and into 1997.

Interest income increased to $962,000 and $1.3 million, respectively, for the 
three- and six-months ended June 30, 1996 from $323,000 and $642,000 in the 
comparable periods in 1995. The increase was largely due to the higher 
average cash balances resulting from receipt of net proceeds of approximately 
$36 million from the follow-on offering of 3,000,000 shares of the Company's 
common stock which closed on March 27, 1996, approximately $5.5 million from 
the exercise on April 24, 1996 by the underwriters of the over allotment 
option in the offering of 450,000 shares and to the receipt of commitment 
fees collected under new collaborations.  Interest expense increased to 
$163,000 and $278,000, respectively for the three- and six-months ended June 
30, 1996 from $55,000 and $125,000 in the comparable period of 1995 as a 
result of higher average debt balances incurred to finance the expansion of 
the Company's facilities and acquisition of lab equipment. 

LIQUIDITY AND CAPITAL RESOURCES

The Company has financed its operations since inception primarily through 
private and public offerings of its capital stock and through corporate 
collaborations.  As of June 30, 1996, the Company had realized approximately 
$89.4 million in net proceeds from offerings of its capital stock.



                                      10

<PAGE>

                        ARRIS PHARMACEUTICAL CORPORATION 

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                      AND RESULTS OF OPERATIONS (CONTINUED)


In addition, the Company has realized $52.6 million from its corporate 
collaborations. (excluding the $5.4 million equity investment in the Company 
made by PNU).  

The Company's principal sources of liquidity are its cash and investments, 
which totaled $68.6 million as of June 30, 1996.  The Company currently has 
approximately $2.1 million available under various capital lease and debt 
lines.  Net cash used by operating activities during the six month period 
ended June 30, 1996 was $3.5 million.  This included receipt of an up-front 
commitment fee from PNU in connection with the combinatorial chemistry 
collaboration agreement which was initiated in March 1996.  Cash used in 
operating activities is expected to fluctuate from quarter to quarter 
depending, in part, upon the timing of cash received from new or expanded 
collaboration agreements.  There can be no assurances that such payments will 
be received on a quarterly basis or at all.  The Company also spent 
approximately $2.7 million for the purchase of property, plant and equipment. 
 Additional equipment will be needed as the Company increases its research 
and development activities.  The Company received net financing of $998,000, 
net of principal repayments under new and existing line of credit and lease 
agreements.

The Company's contract revenues presently are attributable to collaborations 
with PNU, Amgen, Bayer and SB. PNU recently exercised an option to extend the 
human growth hormone collaboration for one year through April 1997.  Amgen 
and Arris recently restructured their erythropoetin collaboration to extend 
through mid-February 1997.  The proof of concept phase of the SB 
collaboration ends in June 1997 and can be extended beyond that into a 
research phase.  All of the Company's other collaborations extend beyond the 
next 12 months.  If the Company is unable to renew any of these 
collaborations or extend the SB collaboration into the research phase, such 
events may have a material adverse effect on the Company's business and 
financial condition.

The cash received by the Company under collaborations for the six months 
ended June 30, 1996 was approximately $10.4 million, which includes an 
up-front payment from PNU for the  combinatorial chemistry agreement signed 
February 29, 1996.  The aggregate collaboration funding to be received by the 
Company in 1996 is expected to be approximately $16 million, excluding 
payments which may be received upon the achievement of certain milestones.  
There can be no assurance that the research support or any milestone payments 
will be realized on a timely basis or at all.

The Company expects that its existing capital resources, including research 
and development revenues from existing collaborations, will enable the 
Company to maintain current and planned operations through at least the next 
48 months.  The Company may need to raise substantial additional capital to 
fund its operations before the end of such period.  The Company expects that 
it will seek such additional funding through new collaborations, through the 
extension of existing collaborations or through public or private equity or 
debt financing. 



                                      11

<PAGE>

                        ARRIS PHARMACEUTICAL CORPORATION 

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                      AND RESULTS OF OPERATIONS (CONTINUED)


There can be no assurance that additional financing will be available on 
acceptable terms or at all.  If additional funds are raised  by issuing 
equity securities, further dilution to stockholders may result.  If adequate 
funds are not available, the Company may be required to delay, to reduce the 
scope of or to eliminate one or more of its research or development programs 
or to obtain funds through arrangements with collaborative partners or others 
that may require the Company to relinquish rights to certain of its 
technologies or products that the Company would otherwise seek to develop or 
commercialize itself.

RECENT EVENTS

On July 9, 1996 the Minority Interest Investors in Arris Pharmaceutical 
Canada, Inc. ("Arris Canada"), exercised their right to exchange their 
interest in Arris Canada for 161,418 shares of the Company's common stock.  
Upon conversion of their shares, Arris Canada will become a wholly owned 
subsidiary of the Company. The fair value of the shares issued to the 
Minority Interest Investors exceeds the book value of the minority interest 
in Arris Canada by $230,000.  This amount will be expensed in the third 
quarter of 1996.

CERTAIN BUSINESS RISKS 

The Company is at an early stage of development.  The Company's technologies 
are, in many cases, new and still under development.  All of the Company's 
proposed products are in research or development and will require significant 
additional research and development efforts prior to any commercial use, 
including extensive preclinical and clinical testing as well as lengthy 
regulatory approval.  There can be no assurance that the Company's research 
and development efforts will be successful, that any of its proposed products 
will prove to be safe and efficacious in the clinical trials or that any 
commercially successful products will ultimately be developed by the Company. 
 In addition, many of the Company's currently proposed products are subject 
to development and licensing arrangements with the Company's collaborators.  
Therefore, the Company is dependent on the research and development efforts 
of these collaborators.  Moreover, the Company is entitled only to a portion 
of the revenues, if any, realized from the commercial sale of any of the 
proposed products covered by the collaborations.  The Company has experienced 
significant operating losses since its inception and expects to incur 
significant operating losses over at least the next several years. The 
development of the Company's technology and proposed products will require a 
commitment of substantial funds to conduct these costly and time consuming 
activities.  All of the Company's revenues to date have been received 
pursuant to the Company's  collaborations.  



                                      12

<PAGE>

                        ARRIS PHARMACEUTICAL CORPORATION 

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                      AND RESULTS OF OPERATIONS (CONTINUED)


Should the Company or its collaborators fail to perform in accordance with 
the terms of any of their agreements, any consequent loss of revenue under 
the agreements could have a material adverse effect on the Company's results 
of operations.  The proposed products under development by the Company have 
never been manufactured on a commercial scale and there can be no assurance 
that such products can be manufactured at a cost or in quantities necessary 
to make them commercially viable.  The Company has no sales, marketing or 
distribution capability.  If any of its products subject to collaborative 
agreements are successfully developed, the Company must rely on its 
collaborators to market such products.  

If the Company develops any products which are not subject to collaborative 
agreements, it must either rely on other large pharmaceutical companies to 
market such products or must develop a marketing and sales force with 
technical expertise and supporting distribution capability in order to market 
such products directly. The foregoing risks reflect the Company's early stage 
of development and the nature of the Company's industry and products.  Also 
inherent in the Company's stage of development is a range of additional 
risks, including competition, uncertainties regarding protection of patents 
and proprietary rights, government regulation and uncertainties regarding 
health care reform. 


                                      13

<PAGE>

                        ARRIS PHARMACEUTICAL CORPORATION 

PART II:  OTHER INFORMATION
- ---------------------------

ITEM 1.          LEGAL PROCEEDINGS
                 None

ITEM 2.          CHANGES IN SECURITIES
                 None

ITEM 3.          DEFAULTS UPON SENIOR SECURITIES
                 None

ITEM 4.          SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

The Company's 1996 Annual Meeting of Stockholders was held on June 5, 1996.  
Stockholders were asked (i) to elect directors to serve for the ensuing year 
and until their successors are elected, (ii) to approve the issuance of a 
sufficient number of shares to satisfy the payment of the second stock 
payment, pursuant to the Company's recent acquisition of Khepri 
Pharmaceutical, Inc., (iii) to approve the issuance of a sufficient number of 
shares to satisfy the exercise of certain exchange rights of the Class B 
Shareholders of Khepri Pharmaceuticals Canada, Inc., (iv) to approve the 
Company's 1989 Stock Plan, as amended, to increase the aggregate number of 
shares of Common Stock authorized for issuance under such plan by 550,000 
shares, to 2,667,500 shares, (v) to approve the Company's Employee Stock 
Purchase Plan, as amended, to increase the number of shares of Common Stock 
authorized for issuance under such plan by 100,000 shares, to 250,000 shares, 
(vi) to ratify the selection of Ernst & Young LLP as independent auditors of 
the Company for its fiscal year ending December 31, 1996.

All of the matters were approved by the stockholders of the Company.  The 
number of shares voted for, against and withheld for each matter were:

                                     FOR          WITHHOLD
                               ------------------------------
Election of Directors:
     John P. Walker               9,401,288        306,283
     Michael J. Ross, Ph.D.       9,401,134        307,437
     Brook H. Byers               9,401,288        306,283
     Anthony B. Evnin, Ph.D.      9,401,288        306,283
     Vaughn M. Kailian            9,401,288        306,283
     Hans U. Sievertsson, Ph.D.   9,400,588        306,983



                                      14

<PAGE>

                        ARRIS PHARMACEUTICAL CORPORATION 


ITEM 4.          SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS (CONTINUED)


                                                                        BROKER/
                                             FOR     AGAINST  ABSTAIN  NON-VOTES
                                          --------------------------------------
Approve Shares for Second Payment
  in connection with the acquisition of 
  Khepri Pharmaceuticals, Inc.            7,856,809     10,047   7,231  861,200
Approve Shares for exchange rights for 
  Khepri Pharmaceuticals, Canada, Inc.    7,551,799    312,647   9,641  861,200
Approve Amendment to the 1989 Stock Plan  8,335,543  1,759,918   9,701  861,200
Approve Amendment to the Employee 
  Stock Purchase Plan                    10,063,469     51,367  10,326  861,200
Selection of Ernst & Young LLP           10,352,439      5,015  21,545  709,200



ITEM 5.          OTHER INFORMATION
                 None

ITEM 6.          EXHIBITS AND REPORTS ON FORM 8-K                             
                          
                 a)       Exhibits
                          27      Financial Data Schedule   
                          
                 b)       Reports on Form 8-K

                          The Company filed no reports on Form 8-K for the 
                          quarter ended June 30, 1996.

                                      15

<PAGE>

                        ARRIS PHARMACEUTICAL CORPORATION

                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the 
registrant has duly caused this report to be signed on its behalf by the 
undersigned thereunto duly authorized.

                         ARRIS PHARMACEUTICAL CORPORATION



Date:  August 13, 1996     By: /s/ John P. Walker
                               -----------------------------------
                               John P. Walker
                               President,  Chief Executive Officer and Director





Date:  August 13, 1996     By: /s/ Daniel H. Petree               
                               -----------------------------------
                               Daniel H. Petree
                               Executive Vice President, Corporate
                               Development and Chief Financial Officer
                               (Principal Financial and Accounting Officer)   



                                      16



<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
This schedule contains summary financial information extracted from the
consolidated balance sheets, statements of operation and statements of cash
flows included in the Company's Form 10-Q for the period ended June 30, 1996,
and is qualified in its entirety by reference to such financial statements
and notes thereto.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   6-MOS
<FISCAL-YEAR-END>                          DEC-31-1996
<PERIOD-START>                             JAN-01-1996
<PERIOD-END>                               JUN-30-1996
<CASH>                                          10,421
<SECURITIES>                                    58,222
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                                52,249
<PP&E>                                          18,314
<DEPRECIATION>                                (10,310)
<TOTAL-ASSETS>                                  79,930
<CURRENT-LIABILITIES>                           16,469
<BONDS>                                              0
                                0
                                          0
<COMMON>                                        14,001
<OTHER-SE>                                      47,114
<TOTAL-LIABILITY-AND-EQUITY>                    79,930
<SALES>                                              0
<TOTAL-REVENUES>                                11,034
<CGS>                                                0
<TOTAL-COSTS>                                   12,511
<OTHER-EXPENSES>                                 2,590
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                 278
<INCOME-PRETAX>                                (3,026)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                            (3,026)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                   (3,026)
<EPS-PRIMARY>                                    (.25)
<EPS-DILUTED>                                    (.25)
        

</TABLE>


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