AFFYMETRIX INC
10-Q, 1997-08-14
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
Previous: ARRIS PHARMACEUTICAL CORP/DE/, 10-Q, 1997-08-14
Next: MINNESOTA BREWING CO, 10-Q, 1997-08-14



<PAGE>
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
 
                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
 
                            ------------------------
 
                                   FORM 10-Q
 
/X/  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
     ACT OF 1934 FOR THE PERIOD ENDED JUNE 30, 1997
 
                                       OR
 
/ /  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
     EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM              TO
                  .
 
                          Commission File No. 0-28218
 
                                AFFYMETRIX, INC.
             (Exact name of Registrant as specified in its charter)
 
<TABLE>
<CAPTION>
<S>                                                      <C>
                      CALIFORNIA                                 77-0319159
            (State or other jurisdiction of                   (I.R.S. Employer
            incorporation or organization)                 Identification Number)
 
   3380 CENTRAL EXPRESSWAY, SANTA CLARA, CALIFORNIA                95051
       (Address of principal executive offices)                  (Zip Code)
</TABLE>
 
       Registrant's telephone number, including area code: (408)731-5000
 
    Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days.
 
                          Yes____X____    No_________
 
            COMMON SHARES OUTSTANDING ON AUGUST 5, 1997: 22,639,521
 
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
<PAGE>
                                AFFYMETRIX, INC.
                               TABLE OF CONTENTS
 
<TABLE>
<CAPTION>
                                                                                                           PAGE
                                                                                                           -----
<S>        <C>                                                                                          <C>
PART I. FINANCIAL INFORMATION
 
Item 1. Financial Statements
 
           Condensed Balance Sheets at June 30, 1997 and December 31, 1996............................           3
 
           Condensed Statements of Operations for the Three and Six Months Ended June 30, 1997 and
             1996.....................................................................................           4
 
           Condensed Statements of Cash Flows for the Six Months Ended June 30, 1997 and 1996.........           5
 
           Notes to Condensed Financial Statements....................................................           6
 
Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations.........
                                                                                                                 8
 
PART II. OTHER INFORMATION
 
Item 4. Submission of Matters to a Vote of Security Holders...........................................          10
 
Item 6. Exhibits and Reports on Form 8-K..............................................................          11
 
SIGNATURES............................................................................................          12
 
EXHIBIT INDEX.........................................................................................          13
</TABLE>
 
                                       2
<PAGE>
PART I. FINANCIAL INFORMATION
ITEM 1. FINANCIAL STATEMENTS
                                AFFYMETRIX, INC.
 
                            CONDENSED BALANCE SHEETS
 
                             (DOLLARS IN THOUSANDS)
 
<TABLE>
<CAPTION>
                                                                                         JUNE 30,    DECEMBER 31,
                                                                                           1997          1996
                                                                                        -----------  ------------
                                                                                        (UNAUDITED)     (NOTE)
<S>                                                                                     <C>          <C>
                                                     ASSETS
 
Current assets:
  Cash, cash equivalents and short-term investments...................................   $  94,645    $  108,982
  Accounts receivables................................................................       4,480         1,888
  Inventories.........................................................................       2,038         1,901
  Other current assets................................................................         393           523
                                                                                        -----------  ------------
    Total current assets..............................................................     101,556       113,294
Net property and equipment............................................................       8,959         5,397
Other assets..........................................................................         985           169
                                                                                        -----------  ------------
                                                                                         $ 111,500    $  118,860
                                                                                        -----------  ------------
                                                                                        -----------  ------------
 
                                      LIABILITIES AND SHAREHOLDERS' EQUITY
 
Current liabilities:
  Accounts payable and other accrued liabilities......................................   $   8,119    $    5,626
 
Noncurrent portion of capital lease obligation........................................         619           741
 
Shareholders' equity:
  Common stock........................................................................     158,750       158,687
  Deferred compensation...............................................................      (1,087)       (1,460)
  Accumulated deficit.................................................................     (54,875)      (44,743)
  Other...............................................................................         (26)            9
                                                                                        -----------  ------------
    Total shareholders' equity........................................................     102,762       112,493
                                                                                        -----------  ------------
                                                                                         $ 111,500    $  118,860
                                                                                        -----------  ------------
                                                                                        -----------  ------------
</TABLE>
 
Note: The balance sheet at December 31, 1996 has been derived from the audited
      financial statements at that date but does not include all of the
      information and footnotes required by generally accepted accounting
      principles for complete financial statements.
 
                            See accompanying notes.
 
                                       3
<PAGE>
                                AFFYMETRIX, INC.
 
                       CONDENSED STATEMENTS OF OPERATIONS
 
          (DOLLARS AND SHARES IN THOUSANDS, EXCEPT PER SHARE AMOUNTS)
 
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                                                        THREE MONTHS ENDED   SIX MONTHS ENDED JUNE
                                                                             JUNE 30,                 30,
                                                                       --------------------  ---------------------
                                                                         1997       1996        1997       1996
                                                                       ---------  ---------  ----------  ---------
<S>                                                                    <C>        <C>        <C>         <C>
Revenue:
  Product............................................................  $     942  $     436  $    1,362  $     457
  Contract and grant.................................................      3,800      1,863       6,188      3,258
                                                                       ---------  ---------  ----------  ---------
    Total revenue....................................................      4,742      2,299       7,550      3,715
 
Cost and expenses:
  Cost of product revenue............................................        979        606       1,844        707
  Research and development...........................................      7,212      4,234      12,710      8,310
  General and administrative.........................................      3,009      1,901       5,815      3,550
                                                                       ---------  ---------  ----------  ---------
    Total operating expenses.........................................     11,200      6,741      20,369     12,567
                                                                       ---------  ---------  ----------  ---------
Loss from operations.................................................     (6,458)    (4,442)    (12,819)    (8,852)
 
Interest income, net.................................................      1,249        665       2,687      1,154
                                                                       ---------  ---------  ----------  ---------
 
Net loss.............................................................  $  (5,209) $  (3,777) $  (10,132) $  (7,698)
                                                                       ---------  ---------  ----------  ---------
                                                                       ---------  ---------  ----------  ---------
 
Net loss per share(1)................................................  $   (0.23) $   (0.21) $    (0.45) $   (0.43)
                                                                       ---------  ---------  ----------  ---------
                                                                       ---------  ---------  ----------  ---------
 
Shares used in computing net loss per share(1).......................     22,613     17,900      22,594     17,782
                                                                       ---------  ---------  ----------  ---------
                                                                       ---------  ---------  ----------  ---------
</TABLE>
 
- ------------------------
 
(1) For the three and six months ended June 30, 1996, shares used in computing
    net loss per share include convertible preferred shares as if they had been
    converted due to the Company's initial public offering in June 1996.
 
                            See accompanying notes.
 
                                       4
<PAGE>
                                AFFYMETRIX, INC.
 
                       CONDENSED STATEMENTS OF CASH FLOWS
 
                INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS
 
                             (DOLLARS IN THOUSANDS)
 
<TABLE>
<CAPTION>
                                                                      SIX MONTHS ENDED JUNE 30,
                                                                   -------------------------------
                                                                     1997                   1996
                                                                   --------               --------
<S>                                                                <C>                    <C>
Cash flows from operating activities:
  Net loss.......................................................  $(10,132)              $ (7,698)
  Adjustments to reconcile net loss to net cash used in operating
    activities:
    Depreciation and amortization................................     1,254                  1,197
    Amortization of investment premiums, net.....................       206                   (637)
    Loss on disposal of equipment................................        --                     62
 
  Change in operating assets and liabilities:
    Accounts receivable..........................................    (2,592)                    77
    Inventories..................................................      (137)                  (880)
    Other current assets.........................................       130                   (392)
    Other assets.................................................      (816)                    --
    Accounts payable and other accrued liabilities...............     2,471                    831
                                                                   --------               --------
      Net cash used in operating activities......................    (9,616)                (7,440)
 
Cash flows from investing activities:
    Capital expenditures.........................................    (4,443)                (1,236)
    Proceeds from the sale of short-term investments.............    66,364                 12,460
    Proceeds from maturities of short-term investments...........    12,252                  2,157
    Purchases of short-term investments..........................   (44,068)               (70,383)
                                                                   --------               --------
      Net cash (used in)/provided by investing activities........    30,105                (57,002)
 
Cash flows from financing activities:
    Issuance of common stock.....................................        63                 83,362
    Principal payments on capital lease obligation...............      (101)                   (92)
                                                                   --------               --------
      Net cash (used in)/provided by financing activities........       (38)                83,270
 
Net increase in cash and cash equivalents........................    20,451                 18,828
Cash and cash equivalents at beginning of period.................    14,143                  2,481
                                                                   --------               --------
Cash and cash equivalents at end of period.......................  $ 34,594               $ 21,309
                                                                   --------               --------
                                                                   --------               --------
</TABLE>
 
                            See accompanying notes.
 
                                       5
<PAGE>
                                AFFYMETRIX, INC.
 
                    NOTES TO CONDENSED FINANCIAL STATEMENTS
 
                                 JUNE 30, 1997
 
                                  (UNAUDITED)
 
NOTE 1. SUMMARY OF SIGNIFICANT ACCOUNTING PRINCIPLES
 
BASIS OF PRESENTATION
 
    The accompanying unaudited condensed financial statements have been prepared
in accordance with generally accepted accounting principles for interim
financial information and with the instructions to Form 10-Q and Article 10 of
Regulation S-X. Accordingly, they do not include all of the information and
footnotes required by generally accepted accounting principles for complete
financial statements. In the opinion of management, all adjustments (consisting
of normal recurring accruals) considered necessary for a fair presentation have
been included. Operating results for the three and six month periods ended June
30, 1997 are not necessarily indicative of the results that may be expected for
the year ending December 31, 1997. For further information, refer to the
financial statements and notes thereto included in the Annual Report on Form
10-K for the year ended December 31, 1996 and the Quarterly Report on Form 10-Q
for the quarter ended March 31, 1997, by Affymetrix, Inc. ("Affymetrix" or the
"Company").
 
REVENUE RECOGNITION
 
    Contract and grant revenue is recorded as earned as defined within the
specific agreements. Payments received in advance under these arrangements are
recorded as deferred revenue until earned. Direct costs associated with these
contracts and grants, other than cost of goods sold, are reported as research
and development expense. Product revenue is recognized upon shipment. Certain
reserves are also recorded upon product shipment.
 
NOTE 2. CASH, CASH EQUIVALENTS AND SHORT-TERM INVESTMENTS
 
    As of June 30, 1997, debt securities held by the Company are comprised of
U.S. Government obligations and U.S. Corporate debt securities. They are
classified as available-for-sale and are carried at fair value with unrealized
gains and losses reported in shareholders' equity.
 
NOTE 3. INVENTORIES
 
    Inventories consist of the following (in thousands):
 
<TABLE>
<CAPTION>
                                                                        JUNE 30,    DECEMBER 31,
                                                                          1997          1996
                                                                       -----------  -------------
<S>                                                                    <C>          <C>
Raw material.........................................................   $     579     $     358
Work in process......................................................          79           178
Finished goods.......................................................       1,380         1,365
                                                                       -----------       ------
    Total............................................................   $   2,038     $   1,901
                                                                       -----------       ------
                                                                       -----------       ------
</TABLE>
 
NOTE 4. SHAREHOLDERS' EQUITY
 
    The Company's initial public offering on June 6, 1996 generated net proceeds
of approximately $83.0 million from the sale of 6.0 million shares. On July 5,
1996, the Company's underwriters purchased 153,000 shares pursuant to the
over-allotment option, for additional net proceeds of $2.1 million. The Company
had 22.6 million shares outstanding at June 30, 1997.
 
                                       6
<PAGE>
                                AFFYMETRIX, INC.
 
              NOTES TO CONDENSED FINANCIAL STATEMENTS (CONTINUED)
 
                                 JUNE 30, 1997
 
                                  (UNAUDITED)
 
NOTE 5. RECENTLY ISSUED ACCOUNTING STANDARD
 
    In February 1997, the Financial Accounting Standards Board issued Statement
No. 128, Earnings Per Share, which is required to be adopted on December 31,
1997. At that time, the Company will be required to change the method currently
used to compute earnings per share. The adoption of FAS 128 will not result in a
change to previously reported earnings per share information.
 
                                       7
<PAGE>
PART I. FINANCIAL INFORMATION
ITEM 2.
 
                    MANAGEMENT'S DISCUSSION AND ANALYSIS OF
                 FINANCIAL CONDITION AND RESULTS OF OPERATIONS
 
    This Management's Discussion and Analysis of Financial Condition and Results
of Operations as of June 30, 1997 and for the three and six month periods ended
June 30, 1997 and 1996 should be read in conjunction with the Management's
Discussion and Analysis of Financial Condition and Results of Operations
included in the Company's Annual Report on Form 10-K for the year ended December
31, 1996 and the Quarterly Report on Form 10-Q for the quarter ended March 31,
1997.
 
    All statements in this discussion that are not historical are forward
looking statements. Such statements are subject to risks and uncertainties that
could cause actual results to differ materially from those projected, including,
but not limited to, uncertainties relating to technological approaches, product
development, manufacturing and market acceptance, uncertainties related to cost
and pricing of the Company's products, dependence on collaborative partners,
uncertainties relating to sole source suppliers, uncertainties relating to FDA
and other regulatory approvals, competition, risks relating to intellectual
property of others, uncertainties of patent protection and uncertainties related
to litigation. These and other risk factors are discussed herein and in the
reports filed with the Securities and Exchange Commission, including the
Company's Annual Report on Form 10-K for the year ended December 31, 1996 and
Quarterly Report on Form 10-Q for the quarter ended March 31, 1997. These
forward-looking statements speak only as of the date hereof. The Company
expressly disclaims any obligation or undertaking to released publicly any
updates or revisions to any forward-looking statements contained herein to
reflect any change in the Company's expectations with regard thereto or any
change in events, conditions, or circumstances on which any such statements are
based.
 
OVERVIEW
 
    Affymetrix is developing GeneChip systems and related applications and
technologies for the acquisition, analysis and management of complex genetic
information. The business and operations of the Company were commenced in 1991
by Affymax N.V. ("Affymax") and were initially conducted within Affymax. In
March 1992, the Company was incorporated as a California corporation and
wholly-owned subsidiary of Affymax. In September 1993, the Company issued equity
securities through a private financing of approximately $21.0 million that
reduced Affymax' ownership to approximately 65%. In March 1995, Glaxo plc, now
Glaxo Wellcome plc ("Glaxo") acquired Affymax, including its then majority
ownership interest in Affymetrix. In August 1995, the Company issued equity
securities through a second private financing of approximately $39.0 million,
reducing Affymax' percentage ownership to approximately 46%. As a result of the
Company's initial public offering of approximately 6.0 million shares in June
1996, Glaxo Wellcome indirectly owned approximately 34% of Affymetrix.
Currently, Glaxo Wellcome owns approximately 33% of Affymetrix.
 
RESULTS OF OPERATIONS
 
    THREE MONTHS AND SIX MONTHS ENDED JUNE 30, 1997 AND 1996
 
    Product revenue was $942,000 and $1.4 million for the three and six months
ended June 30, 1997, respectively, compared to $436,000 and $457,000 in the
three and six months ended June 30, 1996. Contract and grant revenue increased
to $3.8 million for the three months ended June 30, 1997 from $1.9 million for
the three months ended June 30, 1996. Contract and grant revenue increased to
$6.2 million for the six months ended June 30, 1997 from $3.3 million for the
six months ended June 30, 1996. The increase was primarily due to milestone
accomplishments with certain collaborative partners and increases in funding
from the Advanced Technology Program and NIH National Center for Human Genome
Research grants.
 
                                       8
<PAGE>
    Cost of product revenue was $979,000 and $1.8 million for the three and six
months ended June 30, 1997, respectively, compared to $606,000 and $707,000 for
the three and six months ended June 30, 1996. Margins fluctuated during the
three and six month periods due primarily to scale-up costs of production.
 
    Research and development expenses increased to $7.2 million and $12.7
million for the three and six months ended June 30, 1997, respectively, compared
to $4.2 million and $8.3 million for the same periods ending June 30, 1996. The
increase in research and development expenses was attributable primarily to the
hiring of additional research and development personnel and associated purchases
of research supplies. The Company expects research and development spending to
increase over the next several years as product development and core research
efforts continue to expand.
 
    General and administrative expenses increased to $3.0 million for the three
months ended June 30, 1997 compared to $1.9 million for the three months ended
June 30, 1996. General and administrative expenses increased to $5.8 million for
the six months ended June 30, 1997 compared to $3.6 million for the six months
ended June 30, 1996. The increase in general and administrative expenses was
attributable primarily to the hiring of additional management personnel,
professional fees (primarily legal fees) and overall scale-up of the Company's
operations and business development efforts. General and administrative expenses
are expected to continue to increase as the Company expands sales and marketing
and adds management and support staff.
 
    Net interest income was $1.2 million and $2.7 million for the three and six
months ended June 30, 1997, respectively. This compares to net interest income
of $665,000 and $1.2 million for the three and six months ended June 30, 1996.
The increase in net interest income was primarily attributable to increased
investment balances from the initial public offering in June 1996.
 
LIQUIDITY AND CAPITAL RESOURCES
 
    As of June 30, 1997, the Company's cash, cash equivalents, and short-term
investments were $94.6 million compared to $109 million at December 31, 1996.
The decrease is primarily attributable to expansion of core research,
manufacturing and capital spending, and growth in general and administrative
expenses.
 
    Net cash used in operating activities was $9.6 million for the six months
ended June 30, 1997, as compared to $7.4 million for the six months ended June
30, 1996. The increase in net cash used in operating activities resulted
primarily from increases in the Company's net loss and accounts receivables,
offset by an increase in accounts payable and other accrued liabilities. The
Company's investing activities, other than purchases, sales and maturities of
available-for-sale securities, consisted of capital expenditures, which totaled
$4.4 million and $1.2 million for the six months ended June 30, 1997 and 1996,
respectively. These capital expenditures included investments in facilities and
laboratory equipment and scale-up of manufacturing.
 
    The Company anticipates that the existing capital resources will enable it
to maintain currently planned operations through at least 1998. However, this
expectation is based on the Company's current operating plan, which could
change, and therefore the Company could require additional funding sooner than
anticipated. In addition, the Company expects its capital requirements to
increase over the next several years as it expands its facilities and acquires
scientific equipment to support expanded manufacturing and research and
development efforts. The Company's long-term capital expenditure requirements
will depend on numerous factors, including: the progress of its research and
development programs; initiation or expansion of research programs; the
development of commercial scale manufacturing capabilities; its ability to
maintain existing collaborative arrangements and establish and maintain new
collaborative arrangements; the costs involved in preparing, filing,
prosecuting, defending and enforcing intellectual property rights; the
effectiveness of product commercialization activities and arrangements; and
other factors.
 
                                       9
<PAGE>
                                AFFYMETRIX, INC.
 
                                 JUNE 30, 1997
 
PART II. OTHER INFORMATION
 
ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS
 
    (a) Date of meeting.
 
       The Annual Meeting of the Shareholders of Affymetrix, Inc. was held on
       June 6, 1997.
 
    (b) Description of each matter voted on and number of votes cast.
 
<TABLE>
<CAPTION>
                                                                                          FOR        AGAINST   WITHHELD
                                                                                      ------------  ---------  ---------
<C>        <S>                                                                        <C>           <C>        <C>
       1.  To elect directors to serve until the next annual meeting of shareholders
             or until their successors are elected.
           John D. Diekman, Ph.D.                                                       20,211,174          0      5,570
           Stephen P.A. Fodor, Ph.D.                                                    20,211,174          0      5,570
           Paul Berg, Ph.D.                                                             20,211,174          0      5,570
           Douglas M. Hurt                                                              20,211,074          0      5,670
           Vernon R. Loucks, Jr.                                                        19,936,050          0    280,694
           Barry C. Ross, Ph.D.                                                         20,211,174          0      5,670
           David B. Singer                                                              20,209,699          0      7,045
           Lubert Stryer, M.D.                                                          20,210,774          0      5,970
           John A. Young                                                                20,211,099          0      5,645
           Alejandro C. Zaffaroni, Ph.D.                                                20,211,174          0      5,570
 
       2.  To approve an Amendment to the Company's Amended and Restated 1993 Stock     16,159,222    308,164     92,686
             Plan to provide for additional shares.
 
       3.  To approve an Amendment to the Company's Amended and Restated 1993 Stock     19,758,881    273,879     17,895
             Plan to limit the number of shares that may be granted to any
             participant in any one-year period.
 
       4.  To approve an amendment to the Company's Amended and Restated 1993 Stock     19,442,728    382,862     26,472
             Plan to reflect changes to the shareholder approval requirements of
             Securities and Exchange Commission Rule 16b-3.
 
       5.  To ratify the appointment of Ernst & Young LLP as independent auditors of    20,196,862     10,082      9,800
             the Company for the fiscal year ending December 31, 1997.
</TABLE>
 
                                       10
<PAGE>
                                AFFYMETRIX, INC.
 
                                 JUNE 30, 1997
 
ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K
 
    (a) Exhibits:
 
<TABLE>
<CAPTION>
EXHIBIT
NUMBER                           DESCRIPTION OF DOCUMENT
- ------         ------------------------------------------------------------
<S>            <C>
 10.28(1)      Consortium Member Agreement between Affymetrix, Inc.,
                 Bristol-Myers Squibb Company and Millennium
                 Pharmaceuticals, Inc. effective as of April 28, 1997.
 10.29(2)      Sponsored Research Agreement between Whitehead Institute for
                 Biomedical Research, Affymetrix, Inc., Bristol-Myers
                 Squibb Company and Millennium Pharmaceuticals, Inc.
                 effective as of April 28, 1997.
 11.1          Statement of computation of net loss per share.
 27.0          Financial data schedule.
</TABLE>
 
- ------------------------
 
(1) Previously filed as Exhibit Number 10.5 to the quarterly report on Form 10-Q
    of Millennium Pharmaceuticals, Inc. filed August 14, 1997. [SEC File No.
    0-28494]
 
(2) Previously filed as Exhibit Number 10.4 to the quarterly report on Form 10-Q
    of Millennium Pharmaceuticals, Inc. filed August 14, 1997. [SEC File No.
    0-28494]
 
    (b) Reports on Form 8-K:
 
       No reports on Form 8-K were filed during the quarter ended June 30, 1997.
 
                                       11
<PAGE>
                                   SIGNATURES
 
    Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.
 
                                AFFYMETRIX, INC.
 
August 8, 1997                  By:            /s/ EDWARD M. HURWITZ
                                     -----------------------------------------
                                                 Edward M. Hurwitz
                                                 VICE PRESIDENT AND
                                              CHIEF FINANCIAL OFFICER
 
                                       12
<PAGE>
                                AFFYMETRIX, INC.
 
                                 EXHIBIT INDEX
 
                                 JUNE 30, 1997
 
<TABLE>
<CAPTION>
EXHIBIT
NUMBER                                DESCRIPTION OF DOCUMENT
- ------         ----------------------------------------------------------------------
<S>            <C>
 10.28(1)      Consortium Member Agreement between Affymetrix, Inc., Bristol-Myers
                 Squibb Company and Millennium Pharmaceuticals, Inc. effective as of
                 April 28, 1997
 10.29(2)      Sponsored Research Agreement between Whitehead Institute for
                 Biomedical Research, Affymetrix, Inc., Bristol-Myers Squibb Company
                 and Millennium Pharmaceuticals, Inc. effective as of April 28, 1997
 11.1          Statement of computation of net loss per share
 27.0          Financial data schedule
</TABLE>
 
- ------------------------
 
(1) Previously filed as Exhibit Number 10.5 to the quarterly report on Form 10-Q
    of Millennium Pharmaceuticals, Inc. filed August 14, 1997. [SEC File No.
    0-28494]
 
(2) Previously filed as Exhibit Number 10.4 to the quarterly report on Form 10-Q
    of Millennium Pharmaceuticals, Inc. filed August 14, 1997. [SEC File No.
    0-28494]
 
                                       13

<PAGE>
                                                                    EXHIBIT 11.1
                                AFFYMETRIX, INC.
 
                 STATEMENT OF COMPUTATION OF NET LOSS PER SHARE
 
          (DOLLARS AND SHARES IN THOUSANDS, EXCEPT PER SHARE AMOUNTS)
 
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                                                         THREE MONTHS ENDED     SIX MONTHS ENDED
                                                                              JUNE 30,              JUNE 30,
                                                                        --------------------  --------------------
                                                                          1997       1996       1997       1996
                                                                        ---------  ---------  ---------  ---------
<S>                                                                     <C>        <C>        <C>        <C>
Net loss..............................................................  $   5,209  $   3,777  $  10,132  $   7,698
                                                                        ---------  ---------  ---------  ---------
                                                                        ---------  ---------  ---------  ---------
 
Historical primary and fully diluted number of shares:
  Weighted average common shares......................................     22,613      6,564     22,594      3,486
  Shares related to SAB Topic 4D......................................          0          0          0      3,702
                                                                        ---------  ---------  ---------  ---------
Shares used in computing net loss per share...........................     22,613      6,564     22,594      7,188
                                                                        ---------  ---------  ---------  ---------
                                                                        ---------  ---------  ---------  ---------
 
Net loss per share....................................................  $   (0.23) $   (0.58) $   (0.45) $   (1.07)
                                                                        ---------  ---------  ---------  ---------
                                                                        ---------  ---------  ---------  ---------
Pro forma number of shares:
  Weighted average common shares......................................     22,613      6,564     22,594      3,486
  Shares related to SAB Topic 4D......................................          0          0          0      3,702
  Convertible preferred shares, as if converted.......................          0     11,336          0     10,594
                                                                        ---------  ---------  ---------  ---------
 
Shares used in computing pro forma loss per share.....................     22,613     17,900     22,594     17,782
                                                                        ---------  ---------  ---------  ---------
                                                                        ---------  ---------  ---------  ---------
 
Pro forma net loss per share..........................................  $   (0.23) $   (0.21) $   (0.45) $   (0.43)
                                                                        ---------  ---------  ---------  ---------
                                                                        ---------  ---------  ---------  ---------
</TABLE>
 
                                       14

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM ITEM 1
OF FORM 10-Q FOR THE PERIOD ENDED JUNE 30, 1997 AND IS QUALIFIED IN ITS
ENTIRETY BY REFERENCE TO SUCH 10-Q.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   6-MOS
<FISCAL-YEAR-END>                          DEC-31-1997
<PERIOD-START>                             JAN-01-1997
<PERIOD-END>                               JUN-30-1997
<CASH>                                          34,594
<SECURITIES>                                    60,051
<RECEIVABLES>                                    4,480
<ALLOWANCES>                                         0
<INVENTORY>                                      2,038
<CURRENT-ASSETS>                               101,556
<PP&E>                                           8,959
<DEPRECIATION>                                       0
<TOTAL-ASSETS>                                 111,500
<CURRENT-LIABILITIES>                            8,119
<BONDS>                                              0
                                0
                                          0
<COMMON>                                       158,750
<OTHER-SE>                                    (55,988)
<TOTAL-LIABILITY-AND-EQUITY>                   111,500
<SALES>                                          1,362
<TOTAL-REVENUES>                                 7,550
<CGS>                                            1,844
<TOTAL-COSTS>                                    1,844
<OTHER-EXPENSES>                                12,710
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                               2,687
<INCOME-PRETAX>                               (10,132)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                           (10,132)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                  (10,132)
<EPS-PRIMARY>                                   (0.45)
<EPS-DILUTED>                                   (0.45)
        

</TABLE>


© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission