LYNX THERAPEUTICS INC
DEF 14A, 1996-10-03
MEDICINAL CHEMICALS & BOTANICAL PRODUCTS
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                            SCHEDULE 14A INFORMATION
                    Proxy Statement Pursuant to Section 14(a)
                     of the Securities Exchange Act of 1934



Filed by the Registrant
Filed by a Party other than the Registrant

Check the appropriate box:

[ ]    Preliminary Proxy Statement
[ ]    Confidential, for Use of the Commission Only (as permitted by
       Rule 14a-6(e)(2))
[X]    Definitive Proxy Statement
[ ]    Definitive Additional Materials
[ ]    Soliciting Material Pursuant to ss. 240.14a-11(c) or ss. 240.14a-12

                            Lynx Therapeutics, Inc.,
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)

- --------------------------------------------------------------------------------
                   (Name of Person(s) Filing Proxy Statement)

Payment of Filing Fee (Check the appropriate box)

[X]    $125 per Exchange Act Rules 0-11(c)(1)(ii),  14a-6(i)(1), or 14a-6(j)(2).
[ ]    $500 per each party to the  controversy  pursuant  to  Exchange  Act Rule
[ ]    14a-6(i)(3).   Fee  computed  on  table  below  per  Exchange  Act  Rules
[ ]    14a-6(i)(4) and 0-11.

1.     Title of each class of securities to which transaction applies:

- --------------------------------------------------------------------------------
2.     Aggregate number of securities to which transaction applies:

- --------------------------------------------------------------------------------
3.     Per unit price or other underlying value of transaction computed pursuant
       to Exchange Act Rule 0-11:(1)

- --------------------------------------------------------------------------------
4.     Proposed maximum aggregate value of transaction:

- --------------------------------------------------------------------------------
5.     Total fee paid:

- --------------------------------------------------------------------------------
       (1)  Set forth the amount on which the filing fee is calculated and state
       how it was determined.

[X]    Fee paid previously with preliminary materials
[ ]    Check box if any part of the fee is offset as provided  by  Exchange  Act
       Rule  0-11(a)(2) and identify the filing for which the offsetting fee was
       paid previously.  Identify the previous filing by registration  statement
       number, or the Form or Schedule and the date of its filing.

1.     Amount Previously Paid:
                               -------------------------------------------------
2.     Form, Schedule or Registration Statement No.:
                                                    ----------------------------
3.     Filing Party:
                    ------------------------------------------------------------
4.     Date Filed:
                  -------------------------------------------------------------
                    


<PAGE>

                             LYNX THERAPEUTICS, INC.
                             3832 Bay Center Place
                            Hayward, California 94545

                                 PROXY STATEMENT

                                 October 7, 1996

                 INFORMATION CONCERNING SOLICITATION AND VOTING

General

         The  enclosed  consent is solicited on behalf of the Board of Directors
of Lynx  Therapeutics,  Inc., a Delaware  corporation (the  "Company"),  for the
purpose  set forth  herein.  The Company  intends to mail or deliver  this Proxy
Statement  and  accompanying  action by written  consent on or about  October 7,
1996, to certain stockholders entitled to vote for the proposal set forth below.
The Company  will not take any  corporate  action  contemplated  herein prior to
October 28, 1996.

Solicitation

         The Company  will bear the entire  cost of  solicitation  of  consents,
including preparation,  assembly,  printing and mailing of this Proxy Statement,
the consents and any additional information furnished to stockholders. Copies of
solicitation materials may be furnished to banks, brokerage houses,  fiduciaries
and custodians  holding in their names shares of Common Stock beneficially owned
by others to  forward to such  beneficial  owners.  The  Company  may  reimburse
persons  representing  beneficial  owners  of Common  Stock  for their  costs of
forwarding   solicitation   materials  to  such  beneficial   owners.   Original
solicitation of consents by mail may be  supplemented by telephone,  telegram or
personal  solicitation by directors,  officers or other regular employees of the
Company. No additional compensation will be paid to directors, officers or other
regular employees for such services.

Voting Rights and Outstanding Shares

         Only  certain  holders of record of Common  Stock,  Series B  Preferred
Stock,  Series C Preferred  Stock and Series D  Preferred  Stock at the close of
business on October 7, 1996 will  receive this Proxy  Statement  and the written
consent.  At the  close  of  business  on  October  7,  1996,  the  Company  had
outstanding  and  entitled to vote  2,345,466  shares of Common  Stock,  332,288
shares of Series B Preferred  Stock,  123,299 shares of Series C Preferred Stock
and 40,000  shares of Series D Preferred  Stock.  Each share of Common  Stock is
entitled  to one vote,  and each  share of Series B  Preferred  Stock,  Series C
Preferred  Stock and Series D  Preferred  Stock is entitled to one vote for each
share of Common Stock into which such share of Preferred  Stock is  convertible.
Each share of Series B Preferred  Stock,  Series C Preferred  Stock and Series D
Preferred Stock is convertible  into 10 shares of Common Stock.  Certain holders
of outstanding  Common Stock and Preferred  Stock are being asked to take action
by written consent to adopt the proposal described in this Proxy Statement,  and
such  action will be approved  if holders of Common  Stock and  Preferred  Stock
constituting  a  majority  of  the  votes   collectively   attributable  to  the
outstanding  Common Stock and Preferred Stock (calculated on an  as-if-converted
to Common  Stock  basis)  shall sign the  written  consent and deliver it to the
Company  within  the time  frame  specified  above.  To be  effective,  executed
consents must be returned to the Company not more than 60 days after the date of
the executed consent bearing the earliest date.

      All votes will be  tabulated  by the  designated  Inspector  of  Election.
Abstentions and broker non-votes will have the same effect as negative votes.

Revocability of Consents

         Any person giving a consent pursuant to this solicitation has the power
to revoke it at any time before the  requisite  consents  to adopt the  proposal
shall have been received by the Company. A consent may be revoked by filing with
the Secretary of the Company at the Company's  principal  executive office, 3832
Bay Center Place, Hayward, California 94545, a written notice of revocation.


<PAGE>

Stockholder  Proposals

         Proposals  of  stockholders  that are  intended to be  presented at the
Company's  next Annual Meeting of  Stockholders  must be received by the Company
not later than December 10, 1996, in order to be included in the proxy statement
and proxy  relating to that Annual  Meeting.  Stockholders  are also  advised to
review the Company's By-laws, which contain additional requirements with respect
to advance notice of stockholder proposals and director nominations.

Proposal:  Approval of Certificate of Amendment

         The Board of Directors has adopted, subject to stockholder approval, an
amendment to the Company's  Amended and Restated  Certificate  of  Incorporation
solely to decrease the authorized number of shares of the Company's Common Stock
from 120,000,000 shares to 20,000,000 shares and the authorized number of shares
of the Company's Preferred Stock from 25,000,000 shares to 2,000,000 shares.

         Purpose of Decrease. The decrease in the number of authorized shares of
Common Stock and Preferred Stock is intended to decrease the Company's  Delaware
franchise  tax  liability,  which is based in part on the  number of  authorized
shares.  The decrease in the number of authorized shares shall have no effect on
the rights of existing securityholders.

         The consent of holders of Common Stock and Preferred Stock constituting
a majority of the votes  collectively  attributable to the outstanding shares of
Common Stock and Preferred  Stock  (calculated on an  as-if-converted  to Common
Stock basis) will be required to approve this amendment of the Company's Amended
and Restated Certificate of Incorporation.

          MANAGEMENT RECOMMENDS A VOTE IN FAVOR OF THE ABOVE PROPOSAL.


Security Ownership of Certain Beneficial Owners and Management

<TABLE>

         The following table sets forth certain information regarding beneficial
ownership of each class of the  Company's  voting stock as of October 7, 1996 by
(i) each stockholder who is known by the Company to own  beneficially  more than
5% of the Common Stock;  Series B Preferred Stock;  Series C Preferred Stock and
Series D Preferred  Stock;  (ii) each Named  Executive  Officer of the  Company;
(iii)  each  director  of the  Company;  and (iv) all  directors  and  executive
officers  of the  Company as a group.  All Series D  Preferred  Stock is held by
Hoechst  Marion  Roussel as  reflected in the common stock table and as noted in
footnote (6).

<CAPTION>
                                                                        Series B                    Series C
                                          Common Stock(1)           Preferred Stock(1)         Preferred Stock(1)
  Name and Address                        ---------------           ------------------         -----------------
of Beneficial Owners                     Number    Percent(2)       Number    Percent(2)      Number     Percent(2)
- --------------------                     ------    ----------       ------    ----------      ------     ----------

<S>                                     <C>          <C>            <C>          <C>          <C>          <C>
Entities affiliated with the
     Sprout Group(3)                    729,980      23.7%          49,999       15.0%        22,999       18.7%
     3000 Sand Hill Road
     Building 4, Suite 270
     Menlo Park, CA  94025

Entities affiliated with the
     U.S. Venture Partners IV, L.P.(4)  730,000      23.7%          50,000       15.0%        23,000       18.7%
     2180 Sand Hill Road
     Suite 300
     Menlo Park, CA  94025

Cannon Street Fund Ltd.                 565,000      19.4%          40,000       12.0%        16,500       13.4%
     c/o Meridian Venture Group
     R.R. Box 272
     Charlottesville, VA 22314

</TABLE>


                                       2.

<PAGE>

<TABLE>
<CAPTION>
                                                                        Series B                    Series C
                                          Common Stock(1)           Preferred Stock(1)         Preferred Stock(1)
  Name and Address                        ---------------           ------------------         -----------------
of Beneficial Owners                     Number    Percent(2)       Number    Percent(2)      Number     Percent(2)
- --------------------                     ------    ----------       ------    ----------      ------     ----------

<S>                                     <C>          <C>            <C>          <C>          <C>          <C>
Biotechnology Investments Ltd.          545,000      18.8%          40,000       12.0%        14,500       11.8%
     c/o Old Court Limited
     P.O. Box 58
     St. Julian's Court
     St. Peter Port
     Guernsey, Channel Islands

Singapore Bio-Innovations Pte, Ltd.     420,000      15.2%          42,000       12.6%             0          **
     250 North Bridge Road
     24-00 Raffles City Tower
     Singapore  0617

Hoechst Marion Roussel(6)               400,000      14.6%               0          **             0          **
     9300 Ward Parkway
     Kansas City, MO  64114

Asset Management Associates             360,000      13.3%          36,000       10.8%             0          **
  1989 L.P.(7)
     2275 East Bayshore Rd., #150
     Palo Alto, CA  94303

Applied Biosystems a Division of        357,410      13.2%               0          **             0          **
  Perkin Elmer Corporation(5)
     850 Lincoln Centre Drive
     Foster City, CA  94404

Chiron Corporation                      300,000      12.8%               0          **             0          **
     4360 Horton Street
     Emeryville, CA  94608

Entities affiliated with the
     Partech International(8)           300,000      11.3%          15,000        4.5%        15,000       12.2%
     101 California Ave., Suite 3150
     San Francisco, CA  94111

New York Life Insurance Company(9)      270,000      10.3%          20,000        6.0%         7,000        5.7%
     51 Madison Avenue, Rm 203
     New York, NY  10010

Becton Dickinson & Company              233,689       9.1%               0          **             0          **
     One Becton Drive
     Franklin Lakes,  NJ  07417

European Medical Ventures               140,000       5.6%               0          **        14,000       11.4%
     c/o FINOVELEC
     6, rue Ancelle
     92521 Neuilly, Cedex, France

Sam Eletr(9)                            142,590       5.6%               0          **             0          **

William K. Bowes, Jr.(10)               747,720      24.4%          50,000       15.0%        23,000       18.7%

Sydney Brenner(11)                       10,374         **               0          **             0          **

</TABLE>

                                       3.

<PAGE>

<TABLE>
<CAPTION>
                                                                        Series B                    Series C
                                          Common Stock(1)           Preferred Stock(1)         Preferred Stock(1)
  Name and Address                        ---------------           ------------------         -----------------
of Beneficial Owners                     Number    Percent(2)       Number    Percent(2)      Number     Percent(2)
- --------------------                     ------    ----------       ------    ----------      ------     ----------

<S>                                   <C>            <C>           <C>           <C>          <C>          <C>
Timothy G. Geiser(12)                    89,573       3.6%               0          **             0          **

James C. Kitch(13)                       13,606         **             700          **           300          **

Kathleen D. La Porte(14)                729,980      23.8%          49,999       15.0%        22,999       18.7%

David W. Martin, Jr.                    250,000      10.7%               0          **             0          **

Craig C. Taylor(15)                     371,498      13.7%          36,000       10.8%             0          **

Gerald Zon(16)                           89,888       3.6%               0          **             0          **

All directors and officers            2,508,979      57.2%         136,699       41.1%        46,299       37.6%
     as a group (11 persons)

<FN>

**Less than one percent.


 (1)     Except as otherwise noted, and subject to community property laws where
         applicable,  each  person or entity  named in the table has sole voting
         and investment  power with respect to all shares shown as  beneficially
         owned by him, her or it. Beneficial  ownership of Common Stock reflects
         beneficial  ownership of Series B Preferred  Stock,  Series C Preferred
         Stock and Series D  Preferred  Stock as set forth in the table or, with
         respect to Hoechst Marion Roussel, as set forth in footnote (6).

(2)      Percentage of beneficial  ownership is based on 2,345,466 shares of the
         Company's  Common  Stock,  332,288  shares  of the  Company's  Series B
         Preferred  Stock,  123,299  shares of the Company's  Series C Preferred
         Stock and  40,000  shares of the  Company's  Series D  Preferred  Stock
         outstanding  as of October 7, 1996,  except as  otherwise  noted in the
         footnotes.  The  Series B,  Series C and  Series D  Preferred  Stock is
         convertible into Common Stock on a ten-for-one basis.

(3)      Includes 49,999 shares of Series B Preferred Stock and 22,999 shares of
         Series C Preferred Stock held by entities affiliated with Sprout Group.
         Ms. La Porte,  a director of the Company,  is a general  partner of the
         Sprout  Group,  an entity  affiliated  with Sprout  Capital VI,  Sprout
         Capital VII and DLJ Capital.  Ms. La Porte shares the power to vote and
         control the  disposition  of shares held by Sprout  Capital VI,  Sprout
         Capital  VII and DLJ  Capital  and  therefore  may be  deemed to be the
         beneficial  owner of such  shares.  Ms. La Porte  disclaims  beneficial
         ownership of such shares,  except to the extent of her prorata interest
         therein.

(4)      Includes 50,000 shares of Series B Preferred Stock and 23,300 shares of
         Series C Preferred Stock held by entities  affiliated with U.S. Venture
         Partners IV, L.P. ("U.S.V.P. IV") Mr. Bowes, a director of the Company,
         is a general  partner of  Presidio  Management  Group IV,  the  general
         partner of U.S.V.P.  IV. Mr. Bowes shares the power to vote and control
         the  disposition  of shares held by U.S.V.P.  IV and  therefore  may be
         deemed to be the beneficial  owner of such shares.  Mr. Bowes disclaims
         beneficial  ownership  of such  shares,  except  to the  extent  of his
         prorata interest therein.

(5)      Includes  152,400 shares of Common Stock issuable upon exercise of Lynx
         option held by Applied Biosystems that is exercisable within 60 days of
         October 7, 1996.

(6)      Consists  solely of 40,000  shares of Series D Preferred  Stock,  which
         constitutes 100% of the shares of Series D Preferred Stock outstanding.

(7)      Includes  36,000  shares  of  Series B  Preferred  Stock  held by Asset
         Management  Associates  1989 L.P.  ("Asset 1989 L.P.").  Mr. Taylor,  a
         director of the Company, is a general partner of AMC Partners 89, which
         is the 

                                       4.

<PAGE>

         general  partner of Asset 1989 L.P. Mr. Taylor shares the power to vote
         and  control  the  disposition  of shares  held by Asset 1989 L.P.  and
         therefore may be deemed to be the beneficial owner of such shares.  Mr.
         Taylor  disclaims  beneficial  ownership of such shares,  except to the
         extent of his prorata interest  therein.  (8) Includes 15,000 shares of
         Series B Preferred  Stock and 15,000  shares  Series C Preferred  Stock
         held by entities affiliated with Partech International.

(9)      Includes  76,331 shares of Common Stock  issuable upon exercise of Lynx
         stock options held by Dr. Eletr that are exercisable  within 60 days of
         October 7, 1996.

(10)     See Note 4 above.  Common  Stock  amount  also  includes  607 shares of
         Common Stock issuable upon exercise of Perkin Elmer Options held by Mr.
         Bowes that are exercisable immediately.

(11)     Includes  10,374 shares of Common Stock  issuable upon exercise of Lynx
         stock  options held by Sydney  Brenner that are  exercisable  within 60
         days of October 7, 1996.

(12)     Includes  52,750 shares of Common Stock  issuable upon exercise of Lynx
         stock options held by Dr. Geiser that are exercisable within 60 days of
         October 7, 1996.  Also includes 4 shares of Common Stock held of record
         by Dr. Geiser's wife, to which shares Dr. Geiser  disclaims  beneficial
         ownership.

(13)     Includes  700  shares of  Series B  Preferred  Stock and 300  shares of
         Series  C  Preferred  Stock  held by GC&H  Investments,  an  investment
         partnership  of which Mr.  Kitch is a  general  partner.  Common  Stock
         amount also includes 2,999 shares of Common Stock exercisable within 60
         days of October 7, 1996. Mr. Kitch shares the power to vote and control
         the  disposition  of such shares and  therefore may be deemed to be the
         beneficial  owner  of  such  shares.  Mr.  Kitch  disclaims  beneficial
         ownership of such shares,  except to the extent of his prorata interest
         therein.  Common Stock amount also  includes 607 shares of Common Stock
         issuable  upon  exercise of Perkin Elmer Options held by Mr. Kitch that
         are exercisable immediately.

(14)     See Note 3 above.

(15)     See Note 7 above.  Common  Stock  amount  also  includes  607 shares of
         Common Stock issuable upon exercise of Perkin Elmer Options held by Mr.
         Taylor that are exercisable immediately.

(16)     Includes  60,000 shares of Common Stock  issuable upon exercise of Lynx
         stock  options held by Dr. Zon that are  exercisable  within 60 days of
         October  7, 1996.  Also  includes  105  shares of Common  Stock held of
         record by Dr.  Zon's wife and 48 shares of Common Stock  issuable  upon
         exercise  of  Perkin  Elmer  Options  held by Dr.  Zon's  wife that are
         exercisable  within 60 days of October  7, 1996 as to which  shares Dr.
         Zon disclaims beneficial ownership.

(17)     Common Stock amount  includes  204,525  shares of Common Stock issuable
         upon exercise of the  Company's  stock options and Perkin Elmer Options
         held by all directors and officers that are exercisable  within 60 days
         of October 7, 1996. See Notes 9 through 16 above.

</FN>
</TABLE>


                                              By Order of the Board of Directors



                                              James C. Kitch, Secretary

 October 7, 1996


                                       5.


<PAGE>

                            ACTION BY WRITTEN CONSENT
                             OF THE STOCKHOLDERS OF
                   LYNX THERAPEUTICS, INC. SOLICITED ON BEHALF
                            OF THE BOARD OF DIRECTORS


         The  undersigned,  being the  holder of the number of shares of capital
stock of LYNX THERAPEUTICS,  INC., a Delaware  corporation (the "Company"),  set
forth below,  hereby  adopts,  pursuant to Section 228 of the  Delaware  General
Corporation Law, the following resolutions by written consent:

                  WHEREAS,  the Board of  Directors  believes  it is in the best
         interests  of the Company to amend the  Company's  Amended and Restated
         Certificate  of  Incorporation  to  decrease  the number of  authorized
         shares  of Common  Stock to  twenty  million  (20,000,000)  shares  and
         decrease  the number of  authorized  shares of  Preferred  Stock to two
         million  (2,000,000)  shares,  as  set  forth  in  the  Certificate  of
         Amendment (the "Amendment") attached hereto as Exhibit A.

                  NOW,  THEREFORE,   BE  IT  RESOLVED,  that  the  Amendment  in
         substantially  the form attached  hereto be, and it hereby is,  adopted
         and approved.

         IN WITNESS  WHEREOF,  the  undersigned  stockholder  has executed  this
Action by Written Consent as of this    day of         , 1996.

STOCKHOLDER:


______________________________________________
(Signature)



______________________________________________
(Print Name)

Number of Shares of Common Stock:                 _______________
Number of Shares of Series B Preferred Stock:     _______________
Number of Shares of Series C Preferred Stock:     _______________
Number of Shares of Series D Preferred Stock:     _______________



                                       1.




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