LYNX THERAPEUTICS INC
SC 13D, 1997-03-06
MEDICINAL CHEMICALS & BOTANICAL PRODUCTS
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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549




                                  SCHEDULE 13D
                    UNDER THE SECURITIES EXCHANGE ACT OF 1934
                             (Amendment No. ______)*


                                Sam Eletr, Ph.D.
                         ------------------------------
                                (Name of Issuer)


                                  Common Stock
                         ------------------------------
                         (Title of Class of Securities)


                                   551812 30 8
                         ------------------------------
                                 (CUSIP Number)


If filing person has previously  filed a statement of Schedule 13G to report the
acquisition  which  is the  subject  of this  Schedule  13D and is  filing  this
schedule because of Rule 13d-1(b)(3) or (4), check the following |_|.

Check the following box if a fee is being paid with this  statement  |X|. (A fee
is not required only if the filing person:  (1) has a previous statement on file
reporting beneficial ownership of more than five percent of the class securities
described in Item 1; and (2) has filed no amendment subsequent thereto reporting
beneficial ownership of five percent or less of such class.) (See Rule 13d-7).

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).


                                   Page 1 of 4 pages

<PAGE>


- ----------------------------------                       -----------------------
CUSIP No.         551812 30 8               13D              Page 2 of 4 Pages
         -------------------------                                            
- ----------------------------------                       -----------------------

- --------- --------------------------------------------------------------------
   1      NAME OF REPORTING PERSONS

          S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS

          Sam Eletr,  Ph.D.             ###-##-####
- --------- --------------------------------------------------------------------
   2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*      (a)      |_|
                                                                 (b)      |_|
- --------- --------------------------------------------------------------------
   3      SEC USE ONLY

- --------- --------------------------------------------------------------------
   4      SOURCE OF FUNDS*
          PF
- --------- --------------------------------------------------------------------
   5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT 
          TO ITEMS 2(d) pr 2(e) |_|

- --------- --------------------------------------------------------------------
   6      CITIZENSHIP OR PLACE OF ORGANIZATION
          U.S. citizen
- -------------------------- --------- -------------------------------------------
                              7      SOLE VOTING POWER
                                     413,759(1)
   NUMBER OF               --------- -------------------------------------------
     SHARES                   8      SHARED VOTING POWER
 BENEFICIALLY                        0
 OWNED BY EACH             --------- ------------------------------------------
   REPORTING                  9      SOLE DISPOSITIVE POWER
 PERSON WITH                         413,759(1)
                           --------- -------------------------------------------
                              10     SHARED DISPOSITIVE POWER
                                     0
- -------------------------- --------- -------------------------------------------
   11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
          413,759(1)
- --------- ----------------------------------------------------------------------
   12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*
          |_|

- --------- ----------------------------------------------------------------------
   13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 11
          12.3%
- --------- ----------------------------------------------------------------------
   14     TYPE OF REPORTING PERSON*
          IN
- --------- ----------------------------------------------------------------------
- -------- 
(1)  Includes  217,500  shares of Common Stock  issuable  upon  exercise of Lynx
     stock  options  held by Dr.  Eletr that are  exercisable  within 60 days of
     February 28, 1997. Officers of the Company have the right to exercise their
     options  prior to vesting,  subject to a repurchase  agreement  between the
     officer and the Company.


                                Page 2 of 4 pages

<PAGE>


Item 1.  SECURITY AND ISSUER

         (a)      Name of Issuer:  Lynx Therapeutics, Inc.

         (b)      Address of Issuer's Principal Executive Offices:       
                                             3832 Bay Center Place
                                             Hayward, CA  94545

Item 2.  IDENTITY AND BACKGROUND

         (a)      Name of Person Filing:     Sam Eletr, Ph.D.
                                             CEO & Chairman of the Board

         (b)      Address of Principal Business Office or, if None, Residence:
                  3832 Bay Center Place
                  Hayward, CA  94545

         (c)      Citizenship:   U.S.

         (d)      Title of Class of Securities:   COMMON

         (e)      CUSIP Number:   551812 30 8


Item 3.  SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATIONS

         On November 4, 1996, Lynx and its subsidiary,  Spectragen, Inc., merged
pursuant to a Merger Agreement between the Company and the Spectragen employees,
dated October 23, 1996. Prior to the merger, Dr. Eletr,  director of Spectragen,
was issued a Spectragen stock option of one hundred thousand  (100,000)  shares.
The 100,000  shares  were  exercised  subject to a  repurchase  agreement.  Upon
consummation  and pursuant to the merger,  the Reporting Person received 130,000
shares of Lynx Common Stock. The conversion rate was 1:1.3.

         The shares,  beneficially  owned by the Reporting  Person also includes
217,500 shares exercisable, within 60 days of February 28, 1997. Officers of the
Company have the right to exercise their options prior to vesting,  subject to a
repurchase agreement.

         The balance of the shares were acquired by the Reporting Person through
a distribution of Lynx shares from its parent company, Applied Biosystems,  Inc.
in December 1992. Each shareholder of Applied  Biosystems  received a percentage
of Lynx shares based on the number of shares owned. Lynx was spun-out of Applied
Biosystems on October 1, 1992.

         The  source  of the  funds for the  purchases  described  above was the
personal income of the Reporting Person.


Item 4.  PURPOSE OF TRANSACTION

         See Item 3 (above)


                                Page 3 of 4 pages

<PAGE>


Item 5.  INTEREST IN SECURITIES OF ISSUER

         The following  table sets forth certain  information  on the beneficial
ownership of Issuer's common stock by the Reporting  Person.  The percentage set
forth in the table reflects 3,152,148 shares outstanding.

         (a) Beneficial Ownership:   413,759(1)
         (b) Percentage Ownership:   12.3%
         (c) Number of shares as to which such person has:
               (i)   sole power to vote or to direct the vote: 413,759(1)
              (ii)   shared power to vote or to direct the vote:   0
             (iii)   sole power to dispose or to direct the disposition of: 
                     413,759(1)
              (iv)   shared power to dispose or to direct the disposition of:  0

             Instruction.  For computations regarding securities which represent
         a right to acquire an underlying security, see Rule 13d-3(d)(1).



Item 6.  CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS WITH
         RESPECT TO SECURITIES OF THE ISSUER

         none

Item 7.  EXHIBITS

         none


                                    SIGNATURE

       After  reasonable  inquiry and to the best of my knowledge and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.


              March 5, 1997
            -----------------
                     Date


                                      LYNX THERAPEUTICS, INC.




                                      BY:    /s/ Sam Eletr
                                         ---------------------------------------
                                            Sam Eletr, Ph.D.
                                            CEO & Chairman of the Board





                                Page 4 of 4 pages


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