LYNX THERAPEUTICS INC
8-K/A, 1998-05-12
MEDICINAL CHEMICALS & BOTANICAL PRODUCTS
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549




                                   FORM 8-K/A
                                 Amendment No. 1



                Current Report Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934



        Date of Report (Date of earliest event reported): March 10, 1998




                             Lynx Therapeutics, Inc.
             (Exact name of registrant as specified in its charter)





          Delaware                         0-22570               94-3161073
(State or other jurisdiction of          (Commission          (I.R.S. Employer
incorporation or organization)           File Number)        Identification No.)


       3832 Bay Center Place
             Hayward, CA                                          94545
(Address of principal executive offices)                        (Zip Code)


                                 (510) 670-9300
              (Registrant's telephone number, including area code)



                                                        Total number of pages: 7
                                                                     Page 1 of 7

<PAGE>

         The Registrant  hereby amends Item 7 of its Current Report on Form 8-K,
filed with the Commission on March 24, 1998, in its entirety to read as follows:


Item 7.           Financial Statements and Exhibits

(a)               Financial Statements of Businesses acquired

                  Not applicable.

(b)               Pro Forma Financial Information

         The accompanying unaudited pro forma financial information gives effect
to the sale of the Registrant's portfolio of phosphorothioate  antisense patents
and licenses and its  therapeutic  oligonucleotide  manufacturing  facility (the
"Antisense  Business") as if the transaction had occurred on January 1, 1997 for
purposes of the unaudited  statement of operations,  and as of December 31, 1997
for  purposes of the  unaudited  balance  sheet.  No gain from the sale has been
reflected  in  the  unaudited  pro  forma  statement  of  operations  due to the
nonrecurring nature of this transaction.

         The actual gain on the sale of the Antisense  Business will be reported
in Lynx  Therapeutics,  Inc.'s unaudited  financial  statements  included in the
Quarterly Report on Form 10-Q for the period ended March 31, 1998 to be filed no
later than May 15, 1998.

(c)               Exhibits

                  2.1** +   Acquisition Agreement, dated as of February 4, 1998,
                            by and between Inex Pharmaceuticals  Corporation and
                            Lynx.

                  99.1 +    Press release dated February 5, 1998.

**  Portions of this  agreement  have been  deleted  pursuant to our request for
    confidential treatment.

+   Included with the  Registrant's  Current  Report on Form 8-K, filed with the
    Commission on March 24, 1998.

                                       2.

<PAGE>

Item 7. (b)


                             Lynx Therapeutics, Inc.
                    Unaudited Pro Forma Financial Statements


         The following  unaudited pro forma financial  statements  represent the
transaction in which Lynx Therapeutics,  Inc. ("Lynx" or the "Company") sold its
portfolio  of   phosphorothioate   antisense  patents  and  licenses,   and  its
therapeutic oligonucleotide manufacturing facility (collectively, the "Antisense
Business"), to Inex Pharmaceuticals  Corporation ("Inex") of Vancouver,  Canada,
under the terms of the Acquisition  Agreement,  dated as of February 4, 1998, by
and between Inex  Pharmaceuticals  Corporation and Lynx Therapeutics,  Inc. (the
"Acquisition Agreement"). The sale was consummated on March 10, 1998.

         Under the terms of the Acquisition  Agreement,  the Company received $3
million in cash and will  receive 1.2 million  shares of Inex common  stock,  in
three equal  installments,  with the first 400,000 shares  received on March 10,
1998,  and the second and third  installments  of stock to be  received no later
than  two  and  three  years,  respectively,   from  the  closing  date  of  the
transaction.  The Inex  common  stock  received  by Lynx is  subject  to certain
restrictions on trading for specific periods of time following  receipt by Lynx.
Lynx is also entitled to receive  royalties on future sales of  phosphorothioate
antisense  products.  In addition,  Lynx agreed to a royalty-bearing  license to
Inex for its phosphoroamidate  chemistry for certain therapeutic applications in
the fields of cancer and inflammation that will be defined later.

         During  1997,   revenues  from  the  Antisense  Business  were  derived
principally from sales of LR-3280 clinical materials to, and cost reimbursements
from,  Schwarz  Pharma  AG.  These  revenues  represented  11% of the  Company's
revenues in 1997. The Company does not expect the sale of the Antisense Business
to have a significant impact on the Company's future revenues.

         The unaudited financial  information ("Lynx  Therapeutics,  Inc. Net of
Antisense  Business")  gives effect to the sale of the Antisense  Business as if
the  transaction  had occurred on January 1, 1997, for purposes of the unaudited
statement  of  operations,  and as of December  31,  1997,  for  purposes of the
unaudited balance sheet.

         The pro forma  information is presented for illustrative  purposes only
and is not  necessarily  indicative of operating  results or financial  position
that would have  occurred if the sale had been  consummated  as presented in the
accompanying  unaudited pro forma  financial  information  nor is it necessarily
indicative of future operating results or financial position.

         The unaudited pro forma condensed financial  information should be read
in  conjunction  with  the  accompanying  note  and  the  historical   financial
statements,  including the notes  thereto,  as filed with the  Commission on the
Company's Annual Report on Form 10-K for the year ended December 31, 1997.

                                       3.

<PAGE>

Item 7. (b)
<TABLE>
                             Lynx Therapeutics, Inc.

                        Unaudited Pro Forma Balance Sheet
                                December 31, 1997
                                 (In thousands)
<CAPTION>

                                                                                                    Lynx               Lynx
                                                                                             Therapeutics, Inc. Therapeutics, Inc.
Assets                                                                             Lynx           Antisense           Net of
                                                                               Therapeutics,      Business           Antisense
                                                                                 Inc. (a)        Sold (b)          Business (c)
                                                                                ----------------------------------------------
<S>                                                                             <C>               <C>                <C>
Current assets:                                                                
   Cash and cash equivalents                                                    $  8,798          $  3,000           $  11,798
   Short-term investments                                                         16,132               --               16,132
   Accounts receivable                                                               244               --                  244
   Other current assets                                                              199               --                  199
                                                                                ----------------------------------------------
Total current assets                                                              25,373             3,000              28,373
                                                                               
Property and equipment:                                                        
   Leasehold improvements                                                          3,795               --                3,795
   Laboratory and other equipment                                                  3,562            (1,444)              2,118
                                                                                ----------------------------------------------
                                                                                   7,357            (1,444)              5,913
   Less accumulated depreciation                                                  (3,588)            1,234              (2,354)
                                                                                ----------------------------------------------
Net property and equipment                                                         3,769              (210)              3,559
Notes receivable from officers and employees                                         125               (85)                 40
Other assets                                                                          --               883                 883
                                                                                ----------------------------------------------
                                                                                $ 29,267          $  3,588           $  32,855
                                                                                ==============================================
Liabilities and stockholders' equity                                           
Current liabilities:                                                           
   Accounts payable                                                             $    210          $    --            $     210
   Accrued compensation                                                              289               --                  289
   Accrued professional fees                                                         179               --                  179
   Deferred revenue from related parties                                           2,292               --                2,292
   Other accrued liabilities                                                         528                67                 595
                                                                                ----------------------------------------------
Total current liabilities                                                          3,498                67               3,565
Other noncurrent liabilities                                                         179               --                  179
                                                                    
Stockholders' equity:
   Preferred stock, issuable in series, $.001 par value; 2,000,000 shares
     authorized, all shares designated represent convertible preferred stock:

   Series B, 332,288 shares designated, issued, and outstanding at December 31,
     1997; aggregate liquidation value of $16,614 at December 31, 1997            16,091               --               16,091

   Series C, 123,299 shares designated, issued, and outstanding at December 31,
     1997; aggregate liquidation value of $6,165 at December 31, 1997              6,109               --                6,109

   Series D, 40,000 shares  designated, issued, and outstanding at December 31,
     1997; aggregate liquidation value of $5,000 at December 31, 1997              4,989               --                4,989

   Common stock, $.001 par value; 20,000,000 shares authorized,
     5,892,353 shares issued and outstanding at December 31, 1997                 46,640              170               46,810

   Notes receivable from stockholders                                               (460)              --                 (460)

   Deferred compensation                                                          (5,394)              --               (5,394)

   Unrealized gain/(loss) on marketable securities                                   (45)              --                  (45)

   Accumulated deficit                                                           (42,340)            3,351             (38,989)
                                                                                -----------------------------------------------
Total stockholders' equity                                                        25,590             3,521              29,111
                                                                                -----------------------------------------------
                                                                                $ 29,267          $  3,588            $ 32,855
                                                                                ===============================================
<FN>
(a)  Represents  historical  Lynx  Therapeutics,   Inc.,  financial  statements,
     including the Antisense Business sold.

(b)  Reflects the cash and the first  installment  of Inex common stock received
     on the  transaction  date, the Antisense  Business assets sold to Inex, and
     certain other costs associated with the transaction and incurred by Lynx.

(c)  Represents  historical Lynx Therapeutics,  Inc.,  financial statements with
     reflection of the amounts referred to in (b) above.

                             See accompanying note.
</FN>
</TABLE>

                                       4.

<PAGE>


Item 7. (b)
<TABLE>
                                              Lynx Therapeutics, Inc.

                              Unaudited Pro Forma Consolidated Statement of Operations
                                        For the year ended December 31, 1997
                                      (In thousands, except per share amounts)
<CAPTION>


                                                                              Less:   Lynx             Lynx
                                                                           Therapeutics, Inc.   Therapeutics, Inc.
                                                             Lynx               Antisense             Net of
                                                      Therapeutics, Inc.        Business             Antisense
                                                              (a)               Sold (b)           Business (c)
                                                      -------------------------------------------------------------
<S>                                                   <C>                    <C>                  <C>
Net revenues:
   Revenues from collaborative arrangements
     with related parties                             $      4,420           $      523           $    3,897
Product sales and other revenues                               162                  --                   162
                                                      -------------------------------------------------------------
Total revenues                                               4,582                  523                4,059

Operating costs and expenses:
   Research and development                                 14,226                2,892               11,334
   Selling, general and administrative                       1,930                  174                1,756
                                                      -------------------------------------------------------------
Total operating costs and expenses                          16,156                3,066               13,090
                                                      -------------------------------------------------------------

Loss from operations                                       (11,574)              (2,543)              (9,031)

Interest income                                                753                 (140)                 893
                                                      -------------------------------------------------------------
Provisions for income taxes
Net loss                                              $    (10,821)          $   (2,683)          $   (8,138)
                                                      =============================================================

Basic and diluted net loss per share                  $      (3.09)          $    (0.77)          $    (2.32)
                                                      =============================================================

Shares used in basic and diluted per
share computation                                            3,501                3,501                3,501
                                                      =============================================================

<FN>
(a)  Represents  historical  Lynx  Therapeutics,   Inc.,  financial  statements,
     including the Antisense Business.

(b)  Reflects the Antisense Business sold, exclusive of any gain realized on the
     sale.

(c)  Represents historical Lynx Therapeutics,  Inc. financial statements, net of
     the Antisense Business sold, exclusive of any gain realized on the sale.


                                              See accompanying note.
</FN>
</TABLE>

                                       5.

<PAGE>


 Item 7. (b)



                             Lynx Therapeutics, Inc.
                Note to Unaudited Pro Forma Financial Statements


         The pro forma  financial  statements  give effect to the  following pro
forma adjustments:

         The preceding  unaudited pro forma financial  statements  represent the
transaction in which Lynx Therapeutics,  Inc. ("Lynx" or the "Company") sold its
portfolio  of   phosphorothioate   antisense  patents  and  licenses,   and  its
therapeutic  oligonucleotide  manufacturing facility (the "Antisense Business"),
to Inex  Pharmaceuticals  Corporation  ("Inex") of Vancouver,  Canada, under the
terms of the Acquisition Agreement, dated as of February 4, 1998, by and between
Inex Pharmaceuticals  Corporation and the Company (the "Acquisition Agreement").
The sale was consummated on March 10, 1998.

         Under the terms of the Acquisition  Agreement,  the Company received $3
million in cash and will  receive 1.2 million  shares of Inex common  stock,  in
three equal  installments,  with the first 400,000 shares  received on March 10,
1998,  and the second and third  installments  of stock to be  received no later
than  two  and  three  years,  respectively,   from  the  closing  date  of  the
transaction.  The Inex  common  stock  received  by Lynx is  subject  to certain
restrictions on trading for specific periods of time following  receipt by Lynx.
Lynx is also entitled to receive  royalties on future sales of  phosphorothioate
antisense products. In addition, Lynx has agreed to a royalty-bearing license to
Inex for its phosphoroamidate  chemistry for certain therapeutic applications in
the fields of cancer and inflammation that will be defined later.

         During  1997,   revenues  from  the  Antisense  Business  were  derived
principally from sales of LR-3280 clinical materials to, and cost reimbursements
from,  Schwarz  Pharma  AG.  These  revenues  represented  11% of the  Company's
revenues in 1997. The Company does not expect the sale of the Antisense Business
to have a significant impact on the Company's future revenues.

         The unaudited financial  information ("Lynx  Therapeutics,  Inc. Net of
Antisense  Business")  gives effect to the sale of the Antisense  Business as if
the  transaction  had occurred on January 1, 1997, for purposes of the unaudited
statements  of  operations,  and as of December  31,  1997,  for purposes of the
unaudited balance sheet.

                                       6.

<PAGE>


                                   Signatures


         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                   Lynx Therapeutics, Inc.
                                   --------------------------------------------
                                           (Registrant)

May 11, 1998                       /s/  Edward C. Albini
- -----------------------------      --------------------------------------------
           (Date)                  Edward C. Albini
                                   Chief Financial Officer
                                   (Principal Financial and Accounting Officer)

                                       7.



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