SANGSTAT MEDICAL CORP
SC 13G/A, 1999-03-09
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>

         SECURITIES AND EXCHANGE COMMISSION
              Washington, D.C.  20549

                  Schedule 13G

      Under the Securities Exchange Act of 1934

               (Amendment No. 4)

                Sangstat Medical Corp.
                (Name of Issuer)

                     Common
            (Title of Class of Securities)

                    801003 10 4
                  (CUSIP Number)

                February 28, 1999
(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

/X/ Rule 13d-1(b)   / / Rule 13d-1(c)   / / Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purposes of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

           (Continued on following page(s))

<PAGE>

CUSIP No. 801003 10 4
Schedule 13G

1 NAME OF REPORTING PERSONS
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS 

     Dresdner RCM Global Investors LLC  94-3244780
     Dresdner RCM Global Investors 
       US Holdings LLC  94-3244780

2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)  [  ]           (b)      [X]

3 SEC USE ONLY

4 CITIZENSHIP OR PLACE OF ORGANIZATION

     Dresdner RCM Global Investors LLC - DE Limited Liability Co.
     Dresdner RCM Global Investors US Holdings LLC - 
       DE Limited Liability Co.

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH:

5 SOLE VOTING POWER
     Dresdner RCM Global Investors LLC  637,890
     Dresdner RCM Global Investors 
       US Holdings LLC  637,890

6 SHARED VOTING POWER
     Dresdner RCM Global Investors LLC  -0-
     Dresdner RCM Global Investors 
       US Holdings LLC  -0-

7 SOLE DISPOSITIVE POWER
     Dresdner RCM Global Investors LLC  761,090
     Dresdner RCM Global Investors 
       US Holdings LLC  761,090

8 SHARED DISPOSITIVE POWER
     Dresdner RCM Global Investors LLC  -0-
     Dresdner RCM Global Investors 
       US Holdings LLC  -0-

9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     Dresdner RCM Global Investors LLC  761,090
     Dresdner RCM Global Investors 
       US Holdings LLC  761,090

10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     Dresdner RCM Global Investors LLC  4.67%
     Dresdner RCM Global Investors 
       US Holdings LLC  4.67%

12 TYPE OF REPORTING PERSON

     Dresdner RCM Global Investors LLC -IA,OO
     Dresdner RCM Global Investors 
       US Holdings LLC -HC,OO

<PAGE>

Item 1(a) Name of Issuer:

     Sangstat Medical Corp.

Item 1(b) Address of Issuer's Principal Executive Offices:

     1505 Adams Drive
     Menlo Park, CA  94025

Item 2(a) Name of Person Filing:

     Dresdner RCM Global Investors LLC
     Dresdner RCM Global Investors US Holdings LLC

Item 2(b) Address of Principal Business Office or, if none, Residence:

     Four Embarcadero Center
     San Francisco, California  94111

Item 2(c) Citizenship:

     Dresdner RCM Global Investors LLC 
       - DE Limited Liability Co.
     Dresdner RCM Global Investors US Holdings LLC 
       - DE Limited Liability Co.

Item 2(d) Title of Class of Securities:

     Common

Item 2(e) CUSIP Number:

     801003 10 4

Item 3.  If this statement is filed pursuant to Rules 13d-1(b),
or 13d-2(b), check whether the person filing is a:

     (e)  [X]  An investment adviser in accordance with
     Section 240.13d-1(b)(1)(ii)(E).

Item 4.  Ownership.

     See responses to Items 5, 6, 7, 8, 9, and 11 of Cover Page.

Item 5.  Ownership of Five Percent or Less of a Class.
     
     If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities, check the following [X].

Item 6.  Ownership of More than Five Percent on Behalf of Another Person.

     Not Applicable.

Item 7.  Identification and Classification of the Subsidiary Which Acquired the
Security Being Reported on By the Parent Holding Company.

     See Exhibit A.

Item 8.  Identification and Classification of Members of the Group.

     Not Applicable.

Item 9. Notice of Dissolution of Group.

     Not Applicable.

Item 10.  Certification.

     Not Applicable.

By signing below I certify that, to the best of my knowledge and belief, the
securities referred to above were acquired in the ordinary course of business
and were not acquired for the purpose of and do not have the effect of changing
or influencing the control of the issuer of the securities and were not acquired
in connection with or as a participant in any transaction having that purpose or
effect.

                                  SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.

March 9, 1999

By /s/ Susan C. Gause
     Susan C. Gause
     In her capacity as 
     Chief Operating Officer 
     of Dresdner RCM Global 
     Investors LLC and Chief 
     Operating Officer of 
     Dresdner RCM Global 
     Investors US Holdings LLC

<PAGE>

EXHIBIT A

Dresdner RCM Global Investors LLC ("Dresdner RCM") is an investment adviser and
a wholly owned subsidiary of Dresdner RCM US Holdings LLC ("DRCM Holdings"). 
Dresdner RCM Holdings is a Delaware Limited Liability Company.

Dresdner RCM has filed this Schedule 13G pursuant to Section 
240.13d-1(b)(1)(ii)(E) of the Securities Exchange Act of 1934 (the "Act").  
DRCM Holdings has filed this Schedule 13G pursuant to Section 
240.13d-(b)(1)(ii)(G) of the Act.

Dresdner RCM and DRCM Holdings are filing a joint statement on Schedule 13G
under the Act in connection with the common stock of Sangstat Medical Corp.

Dresdner RCM and DRCM Holdings are each responsible for the timely filing of
Schedule 13G and any amendments thereto, and for the completeness and accuracy
of the information concerning each of them contained therein, but none of them
is responsible for the completeness or accuracy of the information of the other.

March 9, 1999

By /s/ Susan C. Gause
     Susan C. Gause
     In her capacity as 
     Chief Operating Officer 
     of Dresdner RCM Global 
     Investors LLC and Chief 
     Operating Officer of 
     Dresdner RCM Global 
     Investors US Holdings LLC




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