<PAGE> PAGE 1
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<PAGE> PAGE 2
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<PAGE> PAGE 3
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<PAGE> PAGE 4
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<PAGE> PAGE 5
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<PAGE> PAGE 6
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<PAGE> PAGE 7
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<PAGE> PAGE 8
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<PAGE> PAGE 9
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<PAGE> PAGE 10
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<PAGE> PAGE 11
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<PAGE> PAGE 12
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<PAGE> PAGE 13
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<PAGE> PAGE 14
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<PAGE> PAGE 15
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<PAGE> PAGE 16
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<PAGE> PAGE 17
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<PAGE> PAGE 18
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<PAGE> PAGE 19
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<PAGE> PAGE 20
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<PAGE> PAGE 21
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063 B000400 7.0
064 A000400 Y
064 B000400 N
066 A000400 N
067 000400 N
068 A000400 N
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069 000400 N
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070 A020400 Y
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070 B020400 N
070 C010400 N
070 C020400 N
070 D010400 N
070 D020400 N
070 E010400 N
070 E020400 N
070 F010400 N
070 F020400 N
070 G010400 N
070 G020400 N
070 H010400 N
070 H020400 N
070 I010400 N
070 I020400 N
070 J010400 Y
070 J020400 N
070 K010400 Y
070 K020400 N
070 L010400 Y
070 L020400 N
070 M010400 N
070 M020400 N
070 N010400 N
070 N020400 N
070 O010400 Y
070 O020400 N
070 P010400 N
070 P020400 N
070 Q010400 N
070 Q020400 N
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070 R020400 N
<PAGE> PAGE 22
071 A000400 8690
071 B000400 1226
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072 A000400 7
072 B000400 204
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072 Z000400 178
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073 A010400 0.2600
073 A020400 0.0000
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<PAGE> PAGE 23
074 K000400 1
074 L000400 146
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074 N000400 7894
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028 A010500 0
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028 B010500 40000
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028 E010500 10000
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<PAGE> PAGE 24
028 H000500 0
045 000500 Y
046 000500 N
047 000500 Y
048 000500 0.400
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055 A000500 N
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<PAGE> PAGE 25
062 P000500 0.0
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064 A000500 N
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068 A000500 N
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070 A010500 Y
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070 E020500 N
070 F010500 N
070 F020500 N
070 G010500 N
070 G020500 N
070 H010500 N
070 H020500 N
070 I010500 N
070 I020500 N
070 J010500 Y
070 J020500 N
070 K010500 Y
070 K020500 N
070 L010500 Y
070 L020500 N
070 M010500 N
070 M020500 N
070 N010500 N
070 N020500 N
070 O010500 Y
070 O020500 N
070 P010500 N
070 P020500 N
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071 A000500 110982
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<PAGE> PAGE 26
071 D000500 133
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<PAGE> PAGE 27
074 N000500 52395
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<PAGE> PAGE 28
047 000600 Y
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<PAGE> PAGE 29
063 A000600 0
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<PAGE> PAGE 30
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<PAGE> PAGE 31
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SIGNATURE NICHOLAS PALMERINO
TITLE MANAGER FUND ACCNTG
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000917469
<NAME> LOOMIS SAYLES INVESTMENT TRUST
<SERIES>
<NUMBER> 1
<NAME> SMALL CAP GROWTH FUND
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<SENIOR-EQUITY> 0
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<SHARES-COMMON-STOCK> 0
<SHARES-COMMON-PRIOR> 0
<ACCUMULATED-NII-CURRENT> (15874)
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<NET-INVESTMENT-INCOME> (5321)
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<NET-CHANGE-FROM-OPS> (3499606)
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<NET-CHANGE-IN-ASSETS> (3499606)
<ACCUMULATED-NII-PRIOR> (10553)
<ACCUMULATED-GAINS-PRIOR> (393219)
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<TABLE> <S> <C>
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<CIK> 0000917469
<NAME> LOOMIS SAYLES INVESTMENT TRUST
<SERIES>
<NUMBER> 2
<NAME> INVESTMENT GRADE FIXED INCOME FUND
<S> <C>
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<PERIOD-END> DEC-31-1995
<INVESTMENTS-AT-COST> 19985283
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</TABLE>
<TABLE> <S> <C>
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<NAME> LOOMIS SAYLES INVESTMENT TRUST
<SERIES>
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<CIK> 0000917469
<NAME> LOOMIS SAYLES INVESTMENT TRUST
<SERIES>
<NUMBER> 4
<NAME> CALIFORNIA TAX FREE INCOME FUND
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<TABLE> <S> <C>
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<CIK> 0000917469
<NAME> LOOMIS SAYLES INVESTMENT TRUST
<SERIES>
<NUMBER> 5
<NAME> MORTGAGE SECURITIES FUND
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<NAME> LOOMIS SAYLES INVESTMENT TRUST
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<NAME> CORE GROWTH FUND
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