BIOSEPRA INC
S-8, 1996-06-10
MISCELLANEOUS CHEMICAL PRODUCTS
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<PAGE>   1
              As filed with the Securities and Exchange Commission
                                on June 10, 1996

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-8

                          REGISTRATION STATEMENT UNDER
                           THE SECURITIES ACT OF 1933

                                  BIOSEPRA INC.
             (Exact name of registrant as specified in its charter)

           DELAWARE                              04-3216867
(State or other jurisdiction of               (I.R.S. Employer
 incorporation or organization)              Identification No.)

                111 LOCKE DRIVE, MARLBOROUGH, MASSACHUSETTS 01752
            (Address of Principal Executive Offices)       (Zip Code)

                            1994 DIRECTOR OPTION PLAN
                            (Full title of the plan)

                              MARK G. BORDEN, ESQ.
                                  HALE AND DORR
                                 60 STATE STREET
                           BOSTON, MASSACHUSETTS 02109
                     (Name and address of agent for service)

                                 (617) 526-6000
          (Telephone number, including area code, of agent for service)

                         CALCULATION OF REGISTRATION FEE

<TABLE>
<CAPTION>
                            Proposed   Proposed
Title of                    maximum    maximum
securities     Amount       offering   aggregate    Amount of
to be          to be        price      offering     registration
registered     registered   per share  price        fee
- ----------     ----------   ---------  ---------    ------------
<S>             <C>         <C>        <C>          <C>    
Common Stock,   30,000      $4.75(1)   $142,500(1)  $100.00
$.01 par        shares
value
</TABLE>

- -------------------------------------------------------------------
(1)      Estimated solely for the purpose of calculating the registration fee,
         and based upon the average of the high and low prices of the Common
         Stock on the Nasdaq National Market on June 3, 1996 in accordance with
         Rules 457(c) and 457(h) of the Securities Act of 1933.
<PAGE>   2
Statement of Incorporation by Reference

         This Registration Statement on Form S-8 incorporates by reference the
contents of the Registration Statement on Form S-8, File No. 33-79396, relating
to the Registrant's 1994 Director Option Plan.

                                      -2-
<PAGE>   3
                                   SIGNATURES

         Pursuant to the requirements of the Securities Act, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the Town of Marlborough, Commonwealth of Massachusetts on the 7th
day of June, 1996.

                                                 BIOSEPRA INC.

                                              By: /s/ Jean-Marie Vogel
                                                 -------------------------------
                                                  Jean-Marie Vogel
                                                  President and
                                                  Chief Executive Officer

                                POWER OF ATTORNEY

         We, the undersigned officers and directors of BioSepra Inc. hereby
severally constitute Jean-Marie Vogel, Peter Castellanos and Mark G. Borden, and
each of them singly, our true and lawful attorneys with full power to them, and
each of them singly, to sign for us and in our names in the capacities indicated
below, the Registration Statement on Form S-8 filed herewith and any and all
subsequent amendments to said Registration Statement, and generally to do all
such things in our names and behalf in our capacities as officers and directors
to enable BioSepra Inc. to comply with all requirements of the Securities and
Exchange Commission, hereby ratifying and confirming our signatures as they may
be signed by said attorneys, or any of them, to said Registration Statement and
any and all amendments thereto.

                                     -3-
<PAGE>   4
         Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed below by the following persons in the capacities and
on the date indicated.

<TABLE>
<CAPTION>
Signature                                Title                                      Date                
- ---------                                -----                                      ----                
<S>                               <C>                                       <C>    <C>                  
/s/ Jean-Marie Vogel              President, Chief                          )                           
- -------------------------         Executive Officer                         )                           
Jean-Marie Vogel                  and Director                              )                           
                                  (Principal Executive                      )                           
                                   and Financial Officer)                   )                           
                                                                            )                           
/s/ Peter M. Castellanos          Controller  (Principal                    )                           
- -------------------------         Accounting Officer)                       )                           
Peter M. Castellanos                                                        )                           
                                                                            )                           
                                                                            )                           
                                                                            )                           
/s/ Timothy J. Barberich          Director                                  )                           
- -------------------------                                                   )                           
Timothy J. Barberich                                                        )                           
                                                                            )                           
                                                                            )      June 7, 1996         
                                                                            )                           
/s/ Robert L. Bratzler            Director                                  )                           
- -------------------------                                                   )                           
Robert L. Bratzler, Ph.D.                                                   )                           
                                                                            )                           
                                                                            )                           
                                                                            )                           
/s/ William M. Cousins, Jr.       Director                                  )                           
- -------------------------                                                   )                           
William M. Cousins, Jr.                                                     )                           
                                                                            )                           
                                                                            )                           
                                                                            )                           
/s/ Alexander M. Klibanov         Director                                  )                           
- -------------------------                                                   )                           
Alexander M. Klibanov, Ph.D.                                                )                           
                                                                            )                           
                                                                            )                           
                                                                            )                           
/s/ Paul A. Looney                Director                                  )                           
- -------------------------                                                   )                           
Paul A. Looney                                                              )                           
                                                                            )                           
                                                                            )                           
                                                                            )                           
/s/ Riccardo Pigliucci            Director                                  )                           
- -------------------------                                                   )                           
Riccardo Pigliucci                                                          )                           
                                                                            )                           
                                                                            )                           
                                                                            )                           
/s/ William E. Rich               Director                                  )                           
- -------------------------                                                   )                           
William E. Rich, Ph.D.                                                      )                           
</TABLE>

                                      -4-
<PAGE>   5
                                  EXHIBIT INDEX
                                  -------------
<TABLE>
<CAPTION>
Exhibit
Number                 Description                                              Page
- -------                -----------                                              ----
<S>                    <C>                                                      <C>    
 4.1                   Certificate of Incorporation
                       of the Registrant, as amended

 4.2                   By-Laws of the Registrant

 4.3 *                 Specimen Certificate of Common Stock of
                       the Registrant                                             -

 5                     Opinion of Hale and Dorr

23.1                   Consent of Hale and Dorr (included in Exhibit 5)           -

23.2                   Consent of Coopers & Lybrand L.L.P.

24                     Power of Attorney (included in the signature pages
                       of this Registration Statement)                            -
</TABLE>

- --------
*  Incorporated herein by reference from the Registrant's Registration
Statement on Form S-1 (File No.  33-75212)

                                       -5-

<PAGE>   1
                          CERTIFICATE OF INCORPORATION

                                       OF

                                 BIOSEPRA INC.

        FIRST.  The name of the Corporation is:

                                 BioSepra Inc.

        SECOND. The address of its registered office in the State of Delaware is
Corporation Trust Center, 1209 Orange Street, in the City of Wilmington, County
of New Castle. The name of its registered agent at such address is The
Corporation Trust Company.

        THIRD.  The nature of the business or purposes to be conducted or
promoted by the Corporation is as follows:

        To engage in any lawful act or activity for which corporations may be
organized under the General Corporation Law of Delaware.

        FOURTH. The total number of shares of all classes of stock which the
Corporation shall have authority to issue is 110,000 shares, consisting of (i)
100,000 shares of Common Stock, $.10 par value per share ("Common Stock"), and
(ii) 10,000 shares of Preferred Stock, $.10 par value per share ("Preferred
Stock"). 

        The following is a statement of the designations and the powers,
privileges and rights, and the qualifications, limitations or restrictions
thereof in respect of each class of capital stock of the Corporation.

A.      COMMON STOCK.

        1.      General.        The voting, dividend and liquidation rights of
the holders of the Common Stock are subject to and qualified by the rights of
the holders of the Preferred Stock of any series as may be designated by the
Board of Directors upon any issuance of the Preferred Stock of any series.

        2.      Voting.         The holders of the Common Stock are entitled to
one vote for each share held at all meetings of stockholders (and written
actions in lieu of meetings). There shall be no cumulative voting.
<PAGE>   2
        The number of authorized shares of Common Stock may be increased or
decreased (but not below the number of shares thereof then outstanding) by the
affirmative vote of the holders of a majority of the stock of the Corporation
entitled to vote, irrespective of the provisions of Section 242(b)(2) of the
General Corporation Law of Delaware.

        3.      Dividends.      Dividends may be declared and paid on the
Common Stock from funds lawfully available therefor as and when determined by
the Board of Directors and subject to any preferential dividend rights of any
then outstanding Preferred Stock.

        4.      Liquidation.    Upon the dissolution or liquidation of the
Corporation, whether voluntary or involuntary, holders of Common Stock will be
entitled to receive all assets of the Corporation available for distribution to
its stockholders, subject to any preferential rights of any then outstanding
Preferred Stock.

B.      PREFERRED STOCK.

        Preferred Stock may be issued from time to time in one or more series,
each of such series to have such terms as stated or expressed herein and in the
resolution or resolutions providing for the issue of such series adopted by the
Board of Directors of the Corporation as hereinafter provided. Any shares of
Preferred Stock which may be redeemed, purchased or acquired by the Corporation
may be reissued except as otherwise provided by law. Different series of
Preferred Stock shall not be construed to constitute different classes of
shares for the purposes of voting by classes unless expressly provided.

        Authority is hereby expressly granted to the Board of Directors from
time to time to issue the Preferred Stock in one or more series, and in
connection with the creation of any such series, by resolution or resolutions
providing for the issue of the shares thereof, to determine and fix such voting
powers, full or limited, or no voting powers, and such designations, preferences
and relative participating, optional or other special rights, and
qualifications, limitations or restrictions thereof, including without
limitation thereof, dividend rights, conversion rights, redemption privileges
and liquidation preferences, as shall be stated and expressed in such
resolutions, all to the full extent now or hereafter permitted by the General
Corporation Law of Delaware. Without limiting the generality of the foregoing,
the resolutions providing for issuance of any series of Preferred Stock may
provide that such series shall be superior or rank equally or be junior to the
Preferred Stock of any other series to the extent permitted by law. Except as
otherwise provided in this Cerificate of Incorporation, no vote of the holders
of the

                                      -2-
<PAGE>   3
Preferred Stock or Common Stock shall be a prerequisite to the designation or
issuance of any shares of any series of the Preferred Stock authorized by and
complying with the conditions of this Certificate of Incorporation, the right
to have such vote being expressly waived by all present and future holders of
the capital stock of the Corporation.

        FIFTH.  The name and mailing address of the sole incorporator are as
follows:

<TABLE>
<CAPTION>
                NAME                            MAILING ADDRESS
               <S>                              <C>
                Victor H. Woolley               BioSepra Inc.
                                                140 Locke Drive
                                                Marlborough, MA 01752
</TABLE>

        SIXTH.  In furtherance of and not in limitation of powers conferred by
statute, it is further provided:

        1.      Election of directors need not be by written ballot.

        2.      The Board of Directors is expressly authorized to adopt, amend
or repeal the By-Laws of the Corporation.

        SEVENTH.  Whenever a compromise or arrangement is proposed between
this corporation and its creditors or any class of them and/or between this
corporation and its stockholders or any class of them, any court of equitable
jurisdiction within the State of Delaware may, on the application in a summary
way of this corporation or of any creditor or stockholder thereof, or on the
application of any receiver or receivers appointed for this corporation under
the provisions of section 291 of Title 8 of the Delaware Code or on the
application of trustees in dissolution or of any receiver or receivers
appointed for this corporation under the provisions of section 279 of Title 8
of the Delaware Code order a meeting of the creditors or class of creditors,
and/or of the stockholders or class of stockholders of this corporation, as the
case may  be, to be summoned in such manner as the said court directs. If a
majority in number representing three-fourths in value of the creditors or
class of creditors, and/or of the stockholders or class of stockholders of this
corporation, as the case may be, agree to any compromise or arrangement and to 
any reorganization of this coporation as consequence of such compromise or
arrangement, the said compromise or arrangement and the said reorganization
shall, if sanctioned by the court to which the said application has been
made, be binding on all the creditors or

                                      -3-
<PAGE>   4
class of creditors, and/or on all the stockholders or class of stockholders, of
this corporation, as the case may be, and also on this corporation.

        EIGHTH. Except to the extent that the General Corporation Law of
Delaware prohibits the elimination or limitation of liability of directors for
breaches of fiduciary duty, no director of the Corporation shall be personally
liable to the Corporation or its stockholders for monetary damages for any
breach of fiduciary duty as a director, notwithstanding any provision of law
imposing such liability. No amendment to or repeal of this provision shall
apply to or have any effect on the liability or alleged liability of any
director of the Corporation for or with respect to any acts or omissions of
such director occurring prior to such amendment.

        NINTH.  1.  Actions, Suits and Proceedings Other than by or in the
Right of the Corporation.  The Corporation shall indemnify each person who was
or is a party or is threatened to be made a party to any threatened, pending or
completed action, suit or proceeding, whether civil, criminal, administrative
or investigative (other than an action by or in the right of the Corporation),
by reason of the fact that he is or was, or has agreed to become, a director or
officer of the Corporation, or is or was serving, or has agreed to serve, at
the request of the Corporation, as a director, officer or trustee of, or in a
similar capacity with, another corporation, partnership, joint venture, trust
or other enterprise (including any employee benefit plan) (all such persons
being referred to hereafter as an "Indemnitee"), or by reason of any action
alleged to have been taken or omitted in such capacity, against all expenses
(including attorneys' fees), judgements, fines and amounts paid in settlement
actually and reasonably incurred by him or on his behalf in connection with
such action, suit or proceeding and any appeal therefrom, if he acted in good
faith and in a manner he reasonably believed to be in, or not opposed to, the
best interests of the Corporation, and, with respect to any criminal action or
proceeding, had no reasonable cause to believe his conduct was unlawful. The
termination of any action, suit or proceeding by judgement, order, settlement,
conviction or upon a plea of nolo contendere or its equivalent, shall not, of
itself, create a presumption that the person did not act in good faith and in a
manner which he reasonably believed to be in, or not opposed to, the best
interests of the Corporation, and, with respect to any criminal action or
proceeding, had reasonable cause to believe that his conduct was unlawful.
Notwithstanding anything to the contrary in this Article, except as set forth
in Section 7 below, the Corporation shall not indemnify an Indemnitee seeking
indemnification in connection with a

                                      -4-
<PAGE>   5
proceeding (or part thereof) initiated by the Indemnitee unless the initiation
thereof was approved by the Board of Directors of the Corporation.

        2.      Actions or Suits by or in the Right of the Corporation.
The Corporation shall indemnify any Indemnitee who was or is a party or is
threatened to be made a party to any threatened, pending or completed action or
suit by or in the right of the Corporation to procure a judgment in its favor
by reason of the fact that he is or was, or has agreed to become, a director or
officer of the Corporation, or is or was serving, or has agreed to serve, at
the request of the Corporation, as a director, officer or trustee of, or in a
similar capacity with, another corporation, partnership, joint venture, trust
or other enterprise (including any employee benefit plan), or by reason of any
action alleged to have been taken or omitted in such capacity, against all
expenses (including attorneys' fees) and amounts paid in settlement actually
and reasonably incurred by him or on his behalf in connection with such action,
suit or proceeding and any appeal therefrom, if he acted in good faith and in a
manner he reasonably believed to be in, or not opposed to, the best interests
of the Corporation, except that no indemnification shall be made in respect of
any claim, issue or matter as to which such person shall have been adjudged to
be liable to the Corporation unless and only to the extent that the Court of
Chancery of Delaware or the court in which such action or suit was brought shall
determine upon application, that, despite the adjudication of such liability
but in view of all the circumstances of the case, such person is fairly and
reasonably entitled to indemnity for such expenses (including attorneys' fees)
which the Court of Chancery of Delaware or such other court shall deem proper.

        3.      Indemnification for Expenses of Successful Party.
Notwithstanding the other provisions of this Article, to the extent that an
Indemnitee has been successful, on the merits or otherwise, in defense of any
action, suit or proceeding referred to in Sections 1 and 2 of this Article, or
in defense of any claim, issue or matter therein, or on appeal from any such
action, suit or proceeding, he shall be indemnified against all expenses
(including attorneys' fees) actually and reasonably incurred by him or on his
behalf in connection therewith. Without limiting the foregoing, if any action,
suit or proceeding is disposed of, on the merits or otherwise (including a
disposition without prejudice), without (i) the disposition being adverse to
the Indemnitee, (ii) an adjudication that the Indemnitee was liable to the
Corporation, (iii) a plea of guilty or nolo contendere by the Indemnitee, (iv)
an adjudication that the Indemnitee did not act in good faith and in a manner
he reasonably believed to be in or not opposed to the best interests of the
Corporation, and (v) with

                                      -5-
<PAGE>   6
respect to any criminal proceeding, an adjudication that the Indemnitee has
reasonable cause to believe his conduct was unlawful, the Indemnitee shall be
considered for the purposes hereof to have been wholly successful with respect
thereto. 

        4.      Notification and Defense of Claim.  As a condition precedent to
his right to be indemnified, the Indemnitee must notify the Corporation in
writing as soon as practicable of any action, suit, proceeding or investigation
involving him for which indemnity will or could be sought.  With respect to any
action, suit, proceeding or investigation of which the Corporation is so
notified, the Corporation will be entitled to participate therein at its own
expense and/or to assume the defense thereof at its own expense, with legal
counsel reasonably acceptable to the Indemnitee. After notice from the
Corporation to the Indemnitee of its election so to assume such defense, the
Corporation shall not be liable to the Indemnitee for any legal or other
expenses subsequently incurred by the Indemnitee in connection with such claim,
other than as provided below in this Section 4. The Indemnitee shall have the
right to employ his own counsel in connection with such claim, but the fees and
expenses of such counsel incurred after notice from the Corporation of its
assumption of the defense thereof shall be at the expense of the Indemnitee
unless (i) the employment of counsel by the Indemnitee has been authorized by
the Corporation, (ii) counsel to the Indemnitee shall have reasonably concluded
that there may be a conflict of interest or position on any significant issue
between the Corporation and the Indemnitee in the conduct of the defense of
such action or (iii) the Corporation shall not in fact have employed counsel to
assume the defense of such action, in each of which cases the fees and expenses
of counsel for the Indemnitee shall be at the expense of the Corporation,
except as otherwise expressly provided by this Article. The Corporation shall
not be entitled, without the consent of the Indemnitee, to assume the defense
of any claim brought by or in the right of the Corporation or as to which
counsel for the Indemnitee shall have reasonably made the conclusion provided
for in clause (ii) above.

        5.      Advance of Expenses.  Subject to the provisions of Section 6
below, in the event that the Corporation does not assume the defense pursuant
to Section 4 of this Article of any action, suit, proceeding or investigation
of which the Corporation receives notice under this Article, any expenses
(including attorneys' fees) incurred by an Indemnitee in defending a civil or
criminal action, suit, proceeding or investigation or any appeal therefrom
shall be paid by the Corporation in advance of the final disposition of such
matter, provided, however, that the payment of such expenses incurred by an
Indemnitee in advance of the final disposition of such matter shall be made
only upon receipt of an

                                      -6-
<PAGE>   7
undertaking by or on behalf of the Indemnitee to repay all amounts so advanced
in the event that it shall ultimately be determined that the Indemnitee is not
entitled to be indemnified by the Corporation as authorized in this Article.
Such undertaking may be accepted without reference to the financial ability of
such person to make such repayment.

        6.      Procedure for Indemnification.  In order to obtain
indemnification or advancement of expenses pursuant to Section 1, 2, 3 or 5 of
this Article, the Indemnitee shall submit to the Corporation a written request,
including in such request such documentation and information as is reasonably
available to the Indemnitee and is reasonably necessary to determine whether
and to what extent the Indemnitee is entitled to indemnification or advancement
of expenses. Any such indemnification or advancement of expenses shall be made
promptly, and in any event within 60 days after receipt by the Corporation of
the written request of the Indemnitee, unless with respect to requests under
Section 1, 2 or 5 the Corporation determines within such 60-day period that the
Indemnitee did not meet the applicable standard of conduct set forth in Section
1 or 2, as the case may be. Such determination shall be made in each instance
by (a) a majority vote of a quorum of the directors of the Corporation
consisting of persons who are not at that time parties to the action, suit or
proceeding in question ("disinterested directors"), (b) if no such quorum is
obtainable, a majority vote of a committee of two or more disinterested
directors, (c) a majority vote of a quorum of the outstanding shares of stock
of all classes entitled to vote for directors, voting as a single class, which
quorum shall consist of stockholders who are not at that time parties to the
action, suit or proceeding in question, (d) independent legal counsel (who may
be regular legal counsel to the Corporation), or (e) a court of competent
jurisdiction.

        7.      Remedies.  The right to indemnification or advances as granted
by this Article shall be enforceable by the Indemnitee in any court of
competent jurisdiction if the Corporation denies such request, in whole or in
part, or if no disposition thereof is made within the 60-day period referred to
above in Section 6. Unless otherwise required by law, the burden of proving
that the Indemnitee is not entitled to indemnification or advancement of
expenses under this Article shall be on the Corporation. Neither the failure of
the Corporation to have made a determination prior to the commencement of such
action that indemnification is proper in the circumstances because the
Indemnitee has met the applicable standard of conduct, nor an actual
determination by the Corporation pursuant to Section 6 that the Indemnitee has
not met such applicable standard of conduct, shall be a defense to the action
or create a presumption that the Indemnitee has not met the

                                      -7-
<PAGE>   8
applicable standard of conduct. The Indemnitee's expenses (including attorneys'
fees) incurred in connection with successfully establishing his right
indemnification, in whole or in part, in any such proceeding shall also be
indemnified by the Corporation.

        8.      Subsequent Amendment.  No amendment, temination or repeal of
this Article or of the relevant provisions of the General Corporation Law of
Delaware or any other applicable laws shall affect or diminish in any way the
rights of any Indemnitee to indemnification under the provisions hereof with
respect to any action, suit, proceeding or investigation arising out of or
relating to any actions, transactions or facts occurring prior to the final
adoption of such amendment, termination or repeal.

        9.      Other Rights.  The indemnification and advancement of expenses
provided by this Article shall not be deemed exclusive of any other rights to
which an Indemnitee seeking indemnification or advancement of expenses may be
entitled under any law (common or statutory), agreement or vote of
stockholders or disinterested directors or otherwise, both as to action in his
official capacity and as to action in any other capacity while holding office
for the Corporation, and shall continue as to an Indemnitee who has ceased to
be a director or officer, and shall inure to the benefit of the estate, heirs,
executors and administrators of the Indemnitee. Nothing contained in this
Article shall be deemed to prohibit, and the Corporation is specifically
authorized to enter into, agreements with officers and directors providing
indemnification rights and procedures different from those set forth in this
Article. In addition, the Corporation may, to the extent authorized from time
to time by its Board of Directors, grant indemnification rights to other
employees or agents of the Corporation or other persons serving the Corporation
and such rights may be equivalent to, or greater or less than, those set forth
in this Article.

        10.     Partial Indemnification.  If an Indemnitee is entitled under
any provision of this Article to indemnification by the Corporation for some or
a portion of the expenses (including attorneys' fees), judgments, fines or
amounts paid in settlement actually and reasonably incurred by him or on his
behalf in connection with any action, suit, proceeding or investigation and any
appeal therefrom but not, however, for the total amount thereof, the
Corporation shall nevertheless indemnify the Indemnitee for the portion of such
expenses (including attorneys' fees), judgments, fines or amounts paid in
settlement to which the Indemnitee is entitled.

                                      -8-
<PAGE>   9
        11.     Insurance.  The Corporation may purchase and maintain
insurance, at its expense, to protect itself and any director, officer, employee
or agent of the Corporation or another corporation, partnership, joint venture,
trust or other enterprise (including any employee benefit plan) against any
expense, liability or loss incurred by him in any such capacity, or arising out
of his status as such, whether or not the Corporation would have the power to
indemnify such person against such expense, liability or loss under the General
Corporation Law of Delaware.

        12.     Merger or Consolidation.  If the Corporation is merged into or
consolidated with another corporation and the Corporation is not the surviving
corporation, the surviving corporation shall assume the obligations of the
Corporation under this Article with respect to any action, suit, proceeding or
investigation arising out of or relating to any actions, transactions or facts
occurring prior to the date of such merger or consolidation.

        13.     Savings Clause.  If this Article or any portion hereof shall be
invalidated on any ground by any court of competent jurisdiction, then the
Corporation shall nevertheless indemnify each Indemnitee as to any expenses
(including attorneys' fees), judgments, fines and amount paid in settlement in
connection with any action, suit, proceeding or investigation, whether civil,
criminal or administrative, including an action by or in the right of the
Corporation, to the fullest extent permitted by any applicable portion of this
Article that shall not have been invalidated and to the fullest extent
permitted by applicable law.

        14.     Definitions.  Terms used herein and defined in Section 145(h)
and Section 145(i) of the General Corporation Law of Delaware shall have the
respective meanings assigned to such terms in such Section 145(h) and Section
145(i). 

        15.     Subsequent Legislation.  If the General Corporation Law of
Delaware is amended after adoption of this Article to expand further the
indemnification permitted to Indemnitees, then the Corporation shall indemnify
such persons to the fullest extent permitted by the General Corporation Law of
Delaware, as so amended.

        TENTH.  The Corporation reserves the right to amend, alter, change or
repeal any provision contained in this Certificate of Incorporation, in the
manner now or hereafter prescribed by statute and this Certificate of
Incorporation, and all rights conferred upon stockholders herein are granted
subject to this reservation.

                                      -9-
<PAGE>   10
        EXECUTED at Marlborough, Massachusetts, on December 31, 1993.

                                        /s/  Victor H. Woolley
                                           --------------------------
                                           Incorporator


                                      -10-
<PAGE>   11
                            CERTIFICATE OF AMENDMENT
                                       OF
                          CERTIFICATE OF INCORPORATION
                                       OF
                                  BIOSEPRA INC.

                     Pursuant to Section 242 of the General
                    Corporation Law of the State of Delaware

         BIOSEPRA INC. (the "Corporation"), organized and existing under and by 
virtue of the General Corporation Law of the State of Delaware, does hereby
certify:

         The Board of Directors of the Corporation, acting pursuant to Section
242 of the General Corporation Law of the State of Delaware, at a meeting duly
called and held, duly adopted the following resolution setting forth an
amendment to the Certificate of Incorporation of the Corporation and declaring
said amendment to be advisable (the "Amendment"). The sole stockholder of the
Corporation, by written action in lieu of a meeting, duly approved the
Amendment, in accordance with the General Corporation law of the State of
Delaware.
         The resolution setting forth the Amendment is as follows:

RESOLVED:         That the first paragraph of Article FOURTH of the Certificate 
                  of Incorporation of the Corporation be and hereby is amended 
                  to read as follows:

                  "FOURTH. The total number of shares of all classes of stock
                  which the Corporation shall have authority to issue is
                  13,000,000 shares, consisting of (i) 12,000,000 shares of
                  Common Stock, $.01 par value per share ("Common Stock"), and
                  (ii) 1,000,000 shares of Preferred Stock, $.01 par value per
                  share ("Preferred Stock")."
<PAGE>   12
         IN WITNESS WHEREOF, the Corporation has caused its corporate seal to be
affixed hereto and the Certificate of Amendment to be signed by its President
and attested by its Secretary this 31st day of January, 1994.




                                            /s/ William E. Rich
                                            ------------------------------------
                                            William E. Rich
                                            President

ATTEST:

/s/ Victor H. Woolley
- -----------------------------------
Victor H. Woolley
Secretary



                                       -2-

<PAGE>   1
                                     BY-LAWS

                                       OF


                                 BIOSEPRA INC.
<PAGE>   2
                                     BY-LAWS

                                TABLE OF CONTENTS

<TABLE>
<CAPTION>
                                                                            PAGE
                                                                            ----

<S>                      <C>                                                <C>
ARTICLE 1 - Stockholders .................................................    1
                                                                              
       Section 1.1       Place of Meetings ...............................    1
       Section 1.2       Annual Meeting ..................................    1
       Section 1.3       Special Meetings ................................    1
       Section 1.4       Notice of Meetings ..............................    1
       Section 1.5       Voting List .....................................    2
       Section 1.6       Quorum ..........................................    2
       Section 1.7       Adjournments ....................................    2
       Section 1.8       Voting and Proxies ..............................    2
       Section 1.9       Action at Meeting ...............................    3
       Section 1.10      Action without Meeting ..........................    3

ARTICLE 2 - Directors ....................................................    3 

       Section 2.1       General Powers ..................................    3
       Section 2.2       Number; Election and Qualification ..............    4
       Section 2.3       Enlargement of the Board ........................    4
       Section 2.4       Tenure ..........................................    4
       Section 2.5       Vacancies .......................................    4
       Section 2.6       Resignation .....................................    4
       Section 2.7       Regular Meetings ................................    4
       Section 2.8       Special Meetings ................................    5
       Section 2.9       Notice of Special Meetings ......................    5
       Section 2.10      Meetings by Telephone Conference
                           Calls .........................................    5
       Section 2.11      Quorum ..........................................    5
       Section 2.12      Action at Meeting ...............................    5
       Section 2.13      Action by Consent ...............................    5
       Section 2.14      Removal .........................................    6
       Section 2.15      Committees ......................................    6
       Section 2.16      Compensation of Directors .......................    6

ARTICLE 3 - Officers .....................................................    7
                                                                              
       Section 3.1       Enumeration .....................................    7
       Section 3.2       Election ........................................    7
       Section 3.3       Qualification ...................................    7
       Section 3.4       Tenure ..........................................    7
</TABLE>


                                       -i-
<PAGE>   3
<TABLE>
<CAPTION>
                                                                           PAGE
                                                                           ----
<S>                      <C>                                               <C>
       Section 3.5       Resignation and Removal ........................     7
       Section 3.6       Vacancies ......................................     8
       Section 3.7       Chairman of the Board and Vice-                   
                            Chairman of the Board .......................     8
       Section 3.8       President ......................................     8
       Section 3.9       Vice Presidents ................................     8
       Section 3.10      Secretary and Assistant Secretaries ............     8
       Section 3.11      Treasurer and Assistant Treasurers .............     9
       Section 3.12      Salaries .......................................     9
                                                                           
ARTICLE 4 - Capital Stock ...............................................    10
                                                                             
       Section 4.1       Issuance of Stock ..............................    10
       Section 4.2       Certificates of Stock ..........................    10
       Section 4.3       Transfers ......................................    11
       Section 4.4       Lost, Stolen or Destroyed                           
                         Certificates ...................................    11
       Section 4.5       Record Date ....................................    11
                                                                             
ARTICLE 5 - General Provisions ..........................................    12
                                                                             
       Section 5.1       Fiscal Year ....................................    12
       Section 5.2       Corporate Seal .................................    12
       Section 5.3       Waiver of Notice ...............................    12
       Section 5.4       Voting of Securities ...........................    12
       Section 5.5       Evidence of Authority ..........................    12
       Section 5.6       Certificate of Incorporation ...................    13
       Section 5.7       Transactions with Interested Parties............    13
       Section 5.8       Severability ...................................    13
       Section 5.9       Pronouns .......................................    14
                                                                             
ARTICLE 6 - Amendments ..................................................    14
                                                                             
       Section 6.1        By the Board of Directors .....................    14
       Section 6.2        By the Stockholders ...........................    14
</TABLE>
   

                                      -ii-
<PAGE>   4
                                     BY-LAWS

                                OF BIOSEPRA INC.


                            ARTICLE 1 - Stockholders

         1.1   Place of Meetings. All meetings of stockholders shall be held at
such place within or without the State of Delaware as may be designated from
time to time by the Board of Directors or the President or, if not so
designated, at the registered office of the corporation.

         1.2   Annual Meeting. The annual meeting of stockholders for the 
election of directors and for the transaction of such other business as may
properly be brought before the meeting shall be held on a date to be fixed by
the Board of Directors or the President (which date shall not be a legal holiday
in the place where the meeting is to be held) at the time and place to be fixed
by the Board of Directors or the President and stated in the notice of the
meeting. If no annual meeting is held in accordance with the foregoing
provisions, the Board of Directors shall cause the meeting to be held as soon
thereafter as convenient. If no annual meeting is held in accordance with the
foregoing provisions, a special meeting may be held in lieu of the annual
meeting, and any action taken at that special meeting shall have the same effect
as if it had been taken at the annual meeting, and in such case all references
in these By-Laws to the annual meeting of the stockholders shall be deemed to
refer to such special meeting.

         1.3   Special Meetings. Special meetings of stockholders may be called 
at any time by the President or by the Board of Directors. Business transacted
at any special meeting of stockholders shall be limited to matters relating to
the purpose or purposes stated in the notice of meeting.

         1.4   Notice of Meetings. Except as otherwise provided by law, written
notice of each meeting of stockholders, whether annual or special, shall be
given not less than 10 nor more than 60 days before the date of the meeting to
each stockholder entitled to vote at such meeting. The notices of all meetings
<PAGE>   5
shall state the place, date and hour of the meeting. The notice of a special
meeting shall state, in addition, the purpose or purposes for which the meeting
is called. If mailed, notice is given when deposited in the United States mail,
postage prepaid, directed to the stockholder at his address as it appears on the
records of the corporation.

         1.5   Voting List. The officer who has charge of the stock ledger of 
the corporation shall prepare, at least 10 days before every meeting of
stockholders, a complete list of the stockholders entitled to vote at the
meeting, arranged in alphabetical order, and showing the address of each
stockholder and the number of shares registered in the name of each stockholder.
Such list shall be open to the examination of any stockholder, for any purpose
germane to the meeting, during ordinary business hours, for a period of at least
10 days prior to the meeting, at a place within the city where the meeting is to
be held. The list shall also be produced and kept at the time and place of the
meeting during the whole time of the meeting, and may be inspected by any
stockholder who is present.

         1.6   Quorum. Except as otherwise provided by law, the Certificate of
Incorporation or these By-Laws, the holders of a majority of the shares of the
capital stock of the corporation issued and outstanding and entitled to vote at
the meeting, present in person or represented by proxy, shall constitute a
quorum for the transaction of business.

         1.7   Adjournments. Any meeting of stockholders may be adjourned to any
other time and to any other place at which a meeting of stockholders may be held
under these By-Laws by the stockholders present or represented at the meeting
and entitled to vote, although less than a quorum, or, if no stockholder is
present, by any officer entitled to preside at or to act as Secretary of such
meeting. It shall not be necessary to notify any stockholder of any adjournment
of less than 30 days if the time and place of the adjourned meeting are
announced at the meeting at which adjournment is taken, unless after the
adjournment a new record date is fixed for the adjourned meeting. At the
adjourned meeting, the corporation may transact any business which might have
been transacted at the original meeting.

         1.8   Voting and Proxies. Each stockholder shall have one vote for each
share of stock entitled to vote held of record by such stockholder and a
proportionate vote for each fractional share so held, unless otherwise provided
in the Certificate of Incorporation. Each stockholder of record entitled to vote
at a meeting of stockholders, or to express consent or dissent to


                                       -2-
<PAGE>   6
corporate action in writing without a meeting, may vote or express such consent
or dissent in person or may authorize another person or persons to vote or act
for him by written proxy executed by the stockholder or his authorized agent and
delivered to the Secretary of the corporation. No such proxy shall be voted or
acted upon after three years from the date of its execution, unless the proxy
expressly provides for a longer period.

         1.9   Action at Meeting. When a quorum is present at any meeting, the
holders of shares of stock representing a majority of the votes cast on a matter
(or if there are two or more classes of stock entitled to vote as separate
classes, then in the case of each such class, the holders of shares of stock of
that class representing a majority of the votes cast on a matter) shall decide
any matter to be voted upon by the stockholders at such meeting, except when a
different vote is required by express provision of law, the Certificate of
Incorporation or these By-Laws. When a quorum is present at any meeting, any
election by stockholders shall be determined by a plurality of the votes cast on
the election.

         1.10  Action without Meeting. Any action required or permitted to be
taken at any annual or special meeting of stockholders of the corporation may be
taken without a meeting, without prior notice and without a vote, if a consent
in writing, setting forth the action so taken, is signed by the holders of
outstanding stock having not less than the minimum number of votes that would be
necessary to authorize or take such action at a meeting at which all shares
entitled to vote on such action were present and voted. Prompt notice of the
taking of corporate action without a meeting by less than unanimous written
consent shall be given to those stockholders who have not consented in writing.



                              ARTICLE 2 - Directors

         2.1   General Powers. The business and affairs of the corporation shall
be managed by or under the direction of a Board of Directors, who may exercise
all of the powers of the corporation except as otherwise provided by law or the
Certificate of Incorporation. In the event of a vacancy in the Board of
Directors, the remaining directors, except as otherwise provided by law, may
exercise the powers of the full Board until the vacancy is filled.


                                       -3-
<PAGE>   7
         2.2   Number; Election and Qualification. The number of directors which
shall constitute the whole Board of Directors shall be determined by resolution
of the stockholders or the Board of Directors, but in no event shall be less
than one. The number of directors may be decreased at any time and from time to
time either by the stockholders or by a majority of the directors then in
office, but only to eliminate vacancies existing by reason of the death,
resignation, removal or expiration of the term of one or more directors. The
directors shall be elected at the annual meeting of stockholders by such
stockholders as have the right to vote on such election. Directors need not be
stockholders of the corporation.

         2.3   Enlargement of the Board. The number of directors may be 
increased at any time and from time to time by the stockholders or by a majority
of the directors then in office.

         2.4   Tenure. Each director shall hold office until the next annual
meeting and until his successor is elected and qualified, or until his earlier
death, resignation or removal.

         2.5   Vacancies. Unless and until filled by the stockholders, any 
vacancy in the Board of Directors, however occurring, including a vacancy
resulting from an enlargement of the Board, may be filled by vote of a majority
of the directors then in office, although less than a quorum, or by a sole
remaining director. A director elected to fill a vacancy shall be elected for
the unexpired term of his predecessor in office, and a director chosen to fill a
position resulting from an increase in the number of directors shall hold office
until the next annual meeting of stockholders and until his successor is elected
and qualified, or until his earlier death, resignation or removal.

         2.6   Resignation. Any director may resign by delivering his written
resignation to the corporation at its principal office or to the President or
Secretary. Such resignation shall be effective upon receipt unless it is
specified to be effective at some other time or upon the happening of some other
event.

         2.7   Regular Meetings. Regular meetings of the Board of Directors may 
be held without notice at such time and place, either within or without the
State of Delaware, as shall be determined from time to time by the Board of
Directors; provided that any director who is absent when such a determination is
made shall be given notice of the determination. A regular meeting of the Board
of Directors may be held without notice immediately after and at the same place
as the annual meeting of stockholders.


                                       -4-
<PAGE>   8
         2.8   Special Meetings. Special meetings of the Board of Directors may 
be held at any time and place, within or without the State of Delaware,
designated in a call by the Chairman of the Board, President, two or more
directors, or by one director in the event that there is only a single director
in office.

         2.9   Notice of Special Meetings. Notice of any special meeting of
directors shall be given to each director by the Secretary or by the officer or
one of the directors calling the meeting. Notice shall be duly given to each
director (i) by giving notice to such director in person or by telephone at
least 48 hours in advance of the meeting, (ii) by sending a telegram or telex,
or delivering written notice by hand, to his last known business or home address
at least 48 hours in advance of the meeting, or (iii) by mailing written notice
to his last known business or home address at least 72 hours in advance of the
meeting. A notice or waiver of notice of a meeting of the Board of Directors
need not specify the purposes of the meeting.

         2.10  Meetings by Telephone Conference Calls. Directors or any members
of any committee designated by the directors may participate in a meeting of the
Board of Directors or such committee by means of conference telephone or similar
communications equipment by means of which all persons participating in the
meeting can hear each other, and participation by such means shall constitute
presence in person at such meeting.

         2.11  Quorum. A majority of the total number of the whole Board of
Directors shall constitute a quorum at all meetings of the Board of Directors.
In the event one or more of the directors shall be disqualified to vote at any
meeting, then the required quorum shall be reduced by one for each such director
so disqualified; provided, however, that in no case shall less than one-third
(1/3) of the number so fixed constitute a quorum. In the absence of a quorum at
any such meeting, a majority of the directors present may adjourn the meeting
from time to time without further notice other than announcement at the meeting,
until a quorum shall be present.

         2.12  Action at Meeting. At any meeting of the Board of Directors at
which a quorum is present, the vote of a majority of those present shall be
sufficient to take any action, unless a different vote is specified by law, the
Certificate of Incorporation or these By-Laws.

         2.13  Action by Consent. Any action required or permitted to be taken 
at any meeting of the Board of Directors or of any committee of the Board of
Directors may be taken without a meeting,


                                       -5-
<PAGE>   9
if all members of the Board or committee, as the case may be, consent to the
action in writing, and the written consents are filed with the minutes of
proceedings of the Board or committee.

         2.14  Removal. Except as otherwise provided by the General Corporation
Law of Delaware, any one or more or all of the directors may be removed, with or
without cause, by the holders of a majority of the shares then entitled to vote
at an election of directors, except that the directors elected by the holders of
a particular class or series of stock may be removed without cause only by vote
of the holders of a majority of the outstanding shares of such class or series.

         2.15  Committees. The Board of Directors may, by resolution passed by a
majority of the whole Board, designate one or more committees, each committee to
consist of one or more of the directors of the corporation. The Board may
designate one or more directors as alternate members of any committee, who may
replace any absent or disqualified member at any meeting of the committee. In
the absence or disqualification of a member of a committee, the member or
members of the committee present at any meeting and not disqualified from
voting, whether or not he or they constitute a quorum, may unanimously appoint
another member of the Board of Directors to act at the meeting in the place of
any such absent or disqualified member. Any such committee, to the extent
provided in the resolution of the Board of Directors and subject to the
provisions of the General Corporation Law of the State of Delaware, shall have
and may exercise all the powers and authority of the Board of Directors in the
management of the business and affairs of the corporation and may authorize the
seal of the corporation to be affixed to all papers which may require it. Each
such committee shall keep minutes and make such reports as the Board of
Directors may from time to time request. Except as the Board of Directors may
otherwise determine, any committee may make rules for the conduct of its
business, but unless otherwise provided by the directors or in such rules, its
business shall be conducted as nearly as possible in the same manner as is
provided in these By-Laws for the Board of Directors.

         2.16  Compensation of Directors. Directors may be paid such 
compensation for their services and such reimbursement for expenses of
attendance at meetings as the Board of Directors may from time to time
determine. No such payment shall preclude any director from serving the
corporation or any of its parent or subsidiary corporations in any other
capacity and receiving compensation for such service.


                                       -6-
<PAGE>   10
                              ARTICLE 3 - Officers

         3.1   Enumeration. The officers of the corporation shall consist of a
President, a Secretary, a Treasurer and such other officers with such other
titles as the Board of Directors shall determine, including a Chairman of the
Board, a Vice-Chairman of the Board, and one or more Vice Presidents, Assistant
Treasurers, and Assistant Secretaries. The Board of Directors may appoint such
other officers as it may deem appropriate.

         3.2   Election. The President, Treasurer and Secretary shall be elected
annually by the Board of Directors at its first meeting following the annual
meeting of stockholders. Other officers may be appointed by the Board of
Directors at such meeting or at any other meeting.

         3.3   Qualification. No officer need be a stockholder. Any two or more 
offices may be held by the same person.

         3.4   Tenure. Except as otherwise provided by law, by the Certificate 
of Incorporation or by these By-Laws, each officer shall hold office until his
successor is elected and qualified, unless a different term is specified in the
vote choosing or appointing him, or until his earlier death, resignation or
removal.

         3.5   Resignation and Removal. Any officer may resign by delivering his
written resignation to the corporation at its principal office or to the
President or Secretary. Such resignation shall be effective upon receipt unless
it is specified to be effective at some other time or upon the happening of some
other event.

         Any officer may be removed at any time, with or without cause, by vote
of a majority of the entire number of directors then in office.

         Except as the Board of Directors may otherwise determine, no officer
who resigns or is removed shall have any right to any compensation as an officer
for any period following his resignation or removal, or any right to damages on
account of such removal, whether his compensation be by the month or by the year
or otherwise, unless such compensation is expressly provided in a duly
authorized written agreement with the corporation.


                                       -7-
<PAGE>   11
         3.6   Vacancies. The Board of Directors may fill any vacancy occurring 
in any office for any reason and may, in its discretion, leave unfilled for such
period as it may determine any offices other than those of President, Treasurer
and Secretary. Each such successor shall hold office for the unexpired term of
his predecessor and until his successor is elected and qualified, or until his
earlier death, resignation or removal.

         3.7   Chairman of the Board and Vice-Chairman of the Board. The Board 
of Directors may appoint a Chairman of the Board and may designate the Chairman
of the Board as Chief Executive Officer. If the Board of Directors appoints a
Chairman of the Board, he shall perform such duties and possess such powers as
are assigned to him by the Board of Directors. If the Board of Directors
appoints a Vice-Chairman of the Board, he shall, in the absence or disability of
the Chairman of the Board, perform the duties and exercise the powers of the
Chairman of the Board and shall perform such other duties and possess such other
powers as may from time to time be vested in him by the Board of Directors.

         3.8   President. The President shall, subject to the direction of the
Board of Directors, have general charge and supervision of the business of the
corporation. Unless otherwise provided by the Board of Directors, he shall
preside at all meetings of the stockholders and, if he is a director, at all
meetings of the Board of Directors. Unless the Board of Directors has designated
the Chairman of the Board or another officer as Chief Executive Officer, the
President shall be the Chief Executive Officer of the corporation. The President
shall perform such other duties and shall have such other powers as the Board of
Directors may from time to time prescribe.

         3.9   Vice Presidents. Any Vice President shall perform such duties and
possess such powers as the Board of Directors or the President may from time to
time prescribe. In the event of the absence, inability or refusal to act of the
President, the Vice President (or if there shall be more than one, the Vice
Presidents in the order determined by the Board of Directors) shall perform the
duties of the President and when so performing shall have all the powers of and
be subject to all the restrictions upon the President. The Board of Directors
may assign to any Vice President the title of Executive Vice President, Senior
Vice President or any other title selected by the Board of Directors.

         3.10  Secretary and Assistant Secretaries. The Secretary shall perform 
such duties and shall have such powers as the Board of Directors or the
President may from time to time prescribe. In addition, the Secretary shall
perform such duties and have such


                                       -8-
<PAGE>   12
powers as are incident to the office of the secretary, including without
limitation the duty and power to give notices of all meetings of stockholders
and special meetings of the Board of Directors, to attend all meetings of
stockholders and the Board of Directors and keep a record of the proceedings, to
maintain a stock ledger and prepare lists of stockholders and their addresses as
required, to be custodian of corporate records and the corporate seal and to
affix and attest to the same on documents.

         Any Assistant Secretary shall perform such duties and possess such
powers as the Board of Directors, the President or the Secretary may from time
to time prescribe. In the event of the absence, inability or refusal to act of
the Secretary, the Assistant Secretary, (or if there shall be more than one, the
Assistant Secretaries in the order determined by the Board of Directors) shall
perform the duties and exercise the powers of the Secretary.

         In the absence of the Secretary or any Assistant Secretary at any
meeting of stockholders or directors, the person presiding at the meeting shall
designate a temporary secretary to keep a record of the meeting.

         3.11   Treasurer and Assistant Treasurers. The Treasurer shall perform
such duties and shall have such powers as may from time to time be assigned to
him by the Board of Directors or the President. In addition, the Treasurer shall
perform such duties and have such powers as are incident to the office of
treasurer, including without limitation the duty and power to keep and be
responsible for all funds and securities of the corporation, to deposit funds of
the corporation in depositories selected in accordance with these By-Laws, to
disburse such funds as ordered by the Board of Directors, to make proper
accounts of such funds, and to render as required by the Board of Directors
statements of all such transactions and of the financial condition of the
corporation.

         The Assistant Treasurers shall perform such duties and possess such
powers as the Board of Directors, the President or the Treasurer may from time
to time prescribe. In the event of the absence, inability or refusal to act of
the Treasurer, the Assistant Treasurer, (or if there shall be more than one, the
Assistant Treasurers in the order determined by the Board of Directors) shall
perform the duties and exercise the powers of the Treasurer.

         3.12   Salaries. Officers of the corporation shall be entitled to such
salaries, compensation or reimbursement as shall be fixed or allowed from time
to time by the Board of Directors.

                
                                       -9-
<PAGE>   13
                            ARTICLE 4 - Capital Stock

         4.1   Issuance of Stock. Unless otherwise voted by the stockholders and
subject to the provisions of the Certificate of Incorporation, the whole or any
part of any unissued balance of the authorized capital stock of the corporation
or the whole or any part of any unissued balance of the authorized capital stock
of the corporation held in its treasury may be issued, sold, transferred or
otherwise disposed of by vote of the Board of Directors in such manner, for such
consideration and on such terms as the Board of Directors may determine.

         4.2   Certificates of Stock. Every holder of stock of the corporation
shall be entitled to have a certificate, in such form as may be prescribed by
law and by the Board of Directors, certifying the number and class of shares
owned by him in the corporation. Each such certificate shall be signed by, or in
the name of the corporation by, the Chairman or Vice-Chairman, if any, of the
Board of Directors, or the President or a Vice President, and the Treasurer or
an Assistant Treasurer, or the Secretary or an Assistant Secretary of the
corporation. Any or all of the signatures on the certificate may be a facsimile.

         Each certificate for shares of stock which are subject to any
restriction on transfer pursuant to the Certificate of Incorporation, the
By-Laws, applicable securities laws or any agreement among any number of
shareholders or among such holders and the corporation shall have conspicuously
noted on the face or back of the certificate either the full text of the
restriction or a statement of the existence of such restriction.

         If the corporation shall be authorized to issue more than one class of
stock or more than one series of any class, the powers, designations,
preferences and relative, participating, optional or other special rights of
each class of stock or series thereof and the qualifications, limitations or
restrictions of such preferences and/or rights shall be set forth in full or
summarized on the face or back of each certificate representing shares of such
class or series of stock, provided that in lieu of the foregoing requirements
there may be set forth on the face or back of each certificate representing
shares of such class or series of stock a statement that the corporation will
furnish without charge to each stockholder who so requests a copy of the full
text of the powers, designations, preferences and relative, participating,

                                                           

                                      -10-
<PAGE>   14
optional or other special rights of each class of stock or series thereof and
the qualifications, limitations or restrictions of such preferences and/or
rights.

         4.3   Transfers. Except as otherwise established by rules and 
regulations adopted by the Board of Directors, and subject to applicable law,
shares of stock may be transferred on the books of the corporation by the
surrender to the corporation or its transfer agent of the certificate
representing such shares properly endorsed or accompanied by a written
assignment or power of attorney properly executed, and with such proof of
authority or the authenticity of signature as the corporation or its transfer
agent may reasonably require. Except as may be otherwise required by law, by the
Certificate of Incorporation or by these By-Laws, the corporation shall be
entitled to treat the record holder of stock as shown on its books as the owner
of such stock for all purposes, including the payment of dividends and the right
to vote with respect to such stock, regardless of any transfer, pledge or other
disposition of such stock until the shares have been transferred on the books of
the corporation in accordance with the requirements of these By-Laws.

         4.4   Lost, Stolen or Destroyed Certificates. The corporation may issue
a new certificate of stock in place of any previously issued certificate alleged
to have been lost, stolen, or destroyed, upon such terms and conditions as the
Board of Directors may prescribe, including the presentation of reasonable
evidence of such loss, theft or destruction and the giving of such indemnity as
the Board of Directors may require for the protection of the corporation or any
transfer agent or registrar.

         4.5   Record Date. The Board of Directors may fix in advance a date as 
a record date for the determination of the stockholders entitled to notice of or
to vote at any meeting of stockholders or to express consent (or dissent) to
corporate action in writing without a meeting, or entitled to receive payment of
any dividend or other distribution or allotment of any rights in respect of any
change, conversion or exchange of stock, or for the purpose of any other lawful
action. Such record date shall not be more than 60 nor less than 10 days before
the date of such meeting, nor more than 10 days after the date of adoption of a
record date for a written consent without a meeting, nor more than 60 days prior
to any other action to which such record date relates.

         If no record date is fixed, the record date for determining
stockholders entitled to notice of or to vote at a meeting of stockholders shall
be at the close of business on the day before the day on which notice is given,
or, if notice is waived, at the


                                      -11-
<PAGE>   15
close of business on the day before the day on which the meeting is held. The
record date for determining stockholders entitled to express consent to
corporate action in writing without a meeting, when no prior action by the Board
of Directors is necessary, shall be the day on which the first written consent
is properly delivered to the corporation. The record date for determining
stockholders for any other purpose shall be at the close of business on the day
on which the Board of Directors adopts the resolution relating to such purpose.

         A determination of stockholders of record entitled to notice of or to
vote at a meeting of stockholders shall apply to any adjournment of the meeting;
provided, however, that the Board of Directors may fix a new record date for the
adjourned meeting.

                         ARTICLE 5 - General Provisions

         5.1   Fiscal Year. Except as from time to time otherwise designated by
the Board of Directors, the fiscal year of the corporation shall begin on the
first day of January in each year and end on the last day of December in each
year.

         5.2   Corporate Seal. The corporate seal shall be in such form as shall
 be approved by the Board of Directors.

         5.3   Waiver of Notice. Whenever any notice whatsoever is required to 
be given by law, by the Certificate of Incorporation or by these By-Laws, a
waiver of such notice either in writing signed by the person entitled to such
notice or such person's duly authorized attorney, or by telegraph, cable or any
other available method, whether before, at or after the time stated in such
waiver, or the appearance of such person or persons at such meeting in person or
by proxy, shall be deemed equivalent to such notice.

         5.4   Voting of Securities. Except as the directors may otherwise
designate, the President or Treasurer may waive notice of, and act as, or
appoint any person or persons to act as, proxy or attorney-in-fact for this
corporation (with or without power of substitution) at, any meeting of
stockholders or shareholders of any other corporation or organization, the
securities of which may be held by this corporation.

         5.5   Evidence of Authority. A certificate by the Secretary, or an 
Assistant Secretary, or a temporary Secretary, as to any action taken by the
stockholders, directors, a committee or any


                                      -12-
<PAGE>   16
officer or representative of the corporation shall as to all persons who rely on
the certificate in good faith be conclusive evidence of such action.

         5.6   Certificate of Incorporation. All references in these By-Laws to
the Certificate of Incorporation shall be deemed to refer to the Certificate of
Incorporation of the corporation, as amended and in effect from time to time.

         5.7   Transactions with Interested Parties. No contract or transaction
between the corporation and one or more of the directors or officers, or between
the corporation and any other corporation, partnership, association, or other
organization in which one or more of the directors or officers are directors or
officers, or have a financial interest, shall be void or voidable solely for
this reason, or solely because the director or officer is present at or
participates in the meeting of the Board of Directors or a committee of the
Board of Directors which authorizes the contract or transaction or solely
because his or their votes are counted for such purpose, if:

               (1)    The material facts as to his relationship or interest and
         as to the contract or transaction are disclosed or are known to the
         Board of Directors or the committee, and the Board or committee in good
         faith authorizes the contract or transaction by the affirmative votes
         of a majority of the disinterested directors, even though the
         disinterested directors be less than a quorum;

               (2)    The material facts as to his relationship or interest and
         as to the contract or transaction are disclosed or are known to the
         stockholders entitled to vote thereon, and the contract or transaction
         is specifically approved in good faith by vote of the stockholders; or

               (3)    The contract or transaction is fair as to the corporation
         as of the time it is authorized, approved or ratified, by the Board of
         Directors, a committee of the Board of Directors, or the stockholders.

         Common or interested directors may be counted in determining the
presence of a quorum at a meeting of the Board of Directors or of a committee
which authorizes the contract or transaction.

         5.8   Severability. Any determination that any provision of these 
By-Laws is for any reason inapplicable, illegal or ineffective shall not affect
or invalidate any other provision of these By-Laws.


                                      -13-
<PAGE>   17
         5.9   Pronouns. All pronouns used in these By-Laws shall be deemed to
refer to the masculine, feminine or neuter, singular or plural, as the identity
of the person or persons may require.

                             ARTICLE 6 - Amendments

         6.1   By the Board of Directors. These By-Laws may be altered, amended 
or repealed or new by-laws may be adopted by the affirmative vote of a majority
of the directors present at any regular or special meeting of the Board of
Directors at which a quorum is present.

         6.2   By the Stockholders. These By-Laws may be altered, amended or
repealed or new by-laws may be adopted by the affirmative vote of the holders of
a majority of the shares of the capital stock of the corporation issued and
outstanding and entitled to vote at any regular meeting of stockholders, or at
any special meeting of stockholders, provided notice of such alteration,
amendment, repeal or adoption of new by-laws shall have been stated in the
notice of such special meeting.


                                      -14-

<PAGE>   1
                                  HALE AND DORR
                                 60 STATE STREET
                           BOSTON, MASSACHUSETTS 02109
                                 (617) 526-6000

                                  June 10, 1996

BioSepra Inc.
111 Locke Drive
Marlborough, MA  01752

         Re:      1994 Director Option Plan

Ladies and Gentlemen:

         We have assisted in the preparation of a Registration Statement on Form
S-8 (the "Registration Statement") to be filed with the Securities and Exchange
Commission relating to an additional 30,000 shares of Common Stock, $.01 par
value per share (the "Shares"), of BioSepra Inc., a Delaware corporation (the
"Company"), issuable under the Company's 1994 Director Option Plan (the "Plan").

         We have examined the Certificate of Incorporation, as amended and the
By-Laws of the Company, and originals, or copies certified to our satisfaction,
of all pertinent records of the meetings of the directors and stockholders of
the Company, the Registration Statement and such other documents relating to the
Company as we have deemed material for the purposes of this opinion.

         In our examination of the foregoing documents, we have assumed the
genuineness of all signatures and the authenticity of all documents submitted to
us as originals, the conformity to original documents of all documents submitted
to us as certified or photostatic copies, and the authenticity of the originals
of such latter documents.

         Based on the foregoing, we are of the opinion that the Company has duly
authorized for issuance the shares of its Common Stock covered by the
Registration Statement to be issued under the Plan, as described in the
Registration Statement, and such shares, when issued in accordance with the
terms of the Plan at a price per share at least equal to the par value per
share of the Common Stock, will be legally issued, fully paid and nonassessable.

                                      -6-
<PAGE>   2
         We hereby consent to the filing of this opinion with the Securities and
Exchange Commission in connection with the Registration Statement.

                                Very truly yours,

                                /s/ HALE AND DORR
                                ---------------------------
                                HALE AND DORR

                                       -7-

<PAGE>   1
                                                                    EXHIBIT 23.2

                       CONSENT OF INDEPENDENT ACCOUNTANTS
                       
         We consent to the incorporation by reference in this Registration
Statement of BioSepra Inc. relating to the 1994 Director Option Plan, of our
report dated February 27, 1996, except as to information contained in Notes I
and T, for which the date is March 29, 1996, on our audits of the consolidated
financial statements and financial statement schedule of BioSepra Inc.

                                                  /s/ COOPERS & LYBRAND L.L.P.
                                                  ----------------------------
                                                      COOPERS & LYBRAND L.L.P.

Boston, Massachusetts
June 7, 1996

                                      -8-


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