BIOSPHERE MEDICAL INC
8-K, EX-99.1, 2000-08-04
PHARMACEUTICAL PREPARATIONS
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                                                                    Exhibit 99.1


BioSphere Medical, Inc. Completes Approximately $13 Million Private Placement


Capital Intended to be Used in Advancing  Worldwide  Commercialization  Strategy
for Embosphere(R)Microspheres

ROCKLAND,  Mass.--(BUSINESS  WIRE)--July  31,  2000--  BioSphere  Medical,  Inc.
(Nasdaq:BSMD  - news),  a medical  device  company that is pioneering the use of
bioengineered  microspheres  to  treat  tumors  and  vascular  malformations  by
occluding  their blood supply,  announced  today that it has completed a private
placement  of  its  Common  Stock  to  selected   institutional  and  accredited
investors,  for aggregate  proceeds of  approximately  $13 million.  The Company
intends  to use the  proceeds  to  fund  working  capital  needs  and  operating
expenses.

Stated  John  Carnuccio,   president  and  chief  executive  officer,  "We  have
accomplished  yet another  major  milestone  with this  financing,  after having
completed several key regulatory and product commercialization  achievements for
Embosphere(R)  Microspheres during the past several months. We are proud to have
added a number of highly regarded financial institutions as investors."

"We intend to use this  additional  capital to help build our direct sales team,
enhance  our  marketing  programs,   expand  clinical  studies  worldwide,   and
accelerate new product  development and other strategic research and development
initiatives.  We believe that, along with this new financing,  BioSphere Medical
is well positioned to capitalize on opportunities  in the growing  embolotherapy
market," concluded Carnuccio.

The Common Stock sold has not been registered  under the Securities Act of 1933,
as amended, and may not be offered or sold in the United States, except pursuant
to the registration  requirements of the Securities Act of 1933, as amended,  or
an applicable exemption from the Securities Act regulation requirements.

This press release shall not constitute an offer to sell or the  solicitation of
an offer to buy the Common Stock. This press release is being issued pursuant to
and in accordance with Rule 135c under the Securities Act.

About BioSphere Medical

BioSphere Medical, Inc., based in Rockland,  Massachusetts,  is a medical device
company  focused  on  embolotherapy,   the  treatment  of  tumors  and  vascular
malformations  by occluding  blood flow.  The Company is  pioneering  the use of
patented and proprietary bioengineered microspheres as a new class of embolics.

This press release  contains  forward-looking  statements that involve risks and
uncertainties,  including  those  relating to the future  sale of the  Company's
products and the long-term  growth of the Company.  Among the important  factors
that could cause  actual  events to differ  materially  from those  indicated by
forward-looking  statements  in this  release  are the failure of the Company to
achieve or maintain necessary regulatory approvals,  either in the United States
or internationally, with respect to the manufacture and sale of its products; to
successfully  develop  and  commercialize  the  Embosphere(R)  Microspheres  and
HepaSphere  SAP(TM)  Microsphere  technologies for uterine artery  embolization,
targeted liver embolization and other applications;  to provide patent and other
proprietary  protection for the Company's products; the absence of or delays and
cancellations of, product orders; the delay in the introduction of new products;
competitive  pressures;  the inability of the Company to raise additional funds,
if needed,  to finance the  development,  marketing,  and sales of its products;
general  economic  conditions;  as well as those risk  factors  detailed  in the
Company's  Annual  Report on form 10-K for the year ended  December 31, 1999 and
other  periodic  reports filed by the Company with the  Securities  and Exchange
Commission.


Contact:

     BioSphere Medical, Inc.
     Robert Palladino
     781-681-7900



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