XECHEM INTERNATIONAL INC
DEF 14C, 1998-11-20
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>   1
                                  SCHEDULE 14C
                            SCHEDULE 14C INFORMATION
                 Information Statement Pursuant to Section 14(c)
             of the Securities Exchange Act of 1934 (Amendment No. )

Check the appropriate box:

[ ]    Preliminary Information Statement

[ ]    Confidential, for Use of the Commission Only (as permitted by Rule 
       14c-5(d)(2))

[X]    Definitive Information Statement

                         Xechem International, Inc.               
       -------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)

Payment of Filing Fee (Check the appropriate box):

[X]    No fee required.

[ ]    Fee computed on table below per Exchange Act Rules 14-5(g) and 0-11.


       1) Title of each class of securities to which transaction applies:

       -------------------------------------------------------------------------

       2) Aggregate number of securities to which transaction applies:

       -------------------------------------------------------------------------

       3) Per unit price or other underlying value of transaction computed 
          pursuant to Exchange Act Rule 0-11 (Set forth the amount on which
          the filing fee is calculated and state how it was determined):

       -------------------------------------------------------------------------

       4) Proposed maximum aggregate value of transaction:

       -------------------------------------------------------------------------

       5) Total fee paid:

       -------------------------------------------------------------------------

[ ]    Fee paid previously with preliminary materials.

[ ]    Check box if any part of the fee is offset as provided by Exchange Act
       Rule 0-11(a)(2) and identify the filing for which the offsetting fee was
       paid previously. Identify the previous filing by registration statement
       number, or the Form or Schedule and the date of its filing.

       1)       Amount Previously Paid:
       
       -------------------------------------------------------------------------
       
       2)       Form, Schedule or Registration Statement No.:
       
       -------------------------------------------------------------------------

       3)       Filing Party:

       -------------------------------------------------------------------------

       4)       Date Filed:

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<PAGE>   2
                           XECHEM INTERNATIONAL, INC.
                          100 JERSEY AVENUE, BUILDING B
                                    SUITE 310
                      NEW BRUNSWICK, NEW JERSEY 08901-3279
                                 (732) 247-3300



                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

===============================================================================

To the Common and Class A Preferred Stockholders of Xechem International, Inc.:

         Notice is hereby given that the annual meeting of stockholders (the
"Meeting" or the "Annual Meeting") of Xechem International, Inc., a Delaware
corporation (the "Corporation"), will be convened at the Corporation's
headquarters, 100 Jersey Ave., Building B, Suite 310, New Brunswick, New Jersey,
on December 11, 1998, at 10:00 a.m. Eastern Standard Time (the "Meeting Date").
All holders of Common Stock, par value $.00001 per share, and Class A Preferred
Stock, par value $.00001 per share, of the Corporation (the "Stockholders") are
entitled to attend the Meeting. The Annual Meeting will be held for the
following purposes:

         (1)      To elect two directors to hold office until the next annual
                  meeting of stockholders or otherwise as provided in the
                  Corporation's By-Laws;

         (2)      To amend the Corporation's Certificate of Incorporation to
                  reflect a one share for 75 shares reverse split of the
                  Corporation's outstanding Common Stock;

         (3)      To vote to approve an increase in the number of shares of 
                  Common Stock which may be issued under the Xechem 
                  International, Inc. Amended and Restated Stock Option Plan;

         (4)      To concur in the selection of Moore Stephens P.C. as the
                  Corporation's independent auditor for the fiscal year ending
                  December 31, 1998; and

         (5)      To transact any other business as may properly come before the
                  Meeting, or any adjournment or postponement thereof.

         Only Stockholders of record at the close of business on October 27,
1998 are entitled to receive notice of the Meeting or any adjournment thereof
(the "Eligible Holders'). A list of Eligible Holders will be available for
inspection at the Corporation's offices for at least 10 days prior to the
Meeting.

                                           By order of the Board of Directors:



                                           Ramesh C. Pandey, Ph.D.
                                           President and Chief Executive Officer


<PAGE>   3





                                 PROXY STATEMENT
                                       FOR
                        ANNUAL MEETING OF STOCKHOLDERS OF
                           XECHEM INTERNATIONAL, INC.
                                DECEMBER 11, 1998

================================================================================

         This proxy statement (the "Proxy Statement") is furnished to the
holders (the "Stockholders") of shares of Common Stock (the "Common Shares"),
par value $.00001 per share, and Class A Preferred Stock (the "Class A Preferred
Shares"), par value $.00001 per share (together, the Common Stock and Class A
Preferred Stock are referred to as the "Shares"), of Xechem International, Inc.,
a Delaware corporation (the "Corporation"), in connection with the solicitation
of proxies by the Corporation's board of directors (the "Board") for use at the
annual meeting of Stockholders (the "Meeting" or the "Annual Meeting"). The
Corporation's By-Laws (the "By-Laws") require the directors to call and hold an
annual meeting of stockholders each year. The Annual Meeting will be convened on
December 11, 1998, at approximately 10:00 a.m. Eastern Standard Time, and any
adjournment or postponement thereof. Copies of this Proxy Statement, and the
enclosed form of proxy were first sent or given to Stockholders on or about
November 19, 1998. Stockholders who wish to attend the Meeting should contact
the Corporation at (732) 247-3300 so that arrangements can be made.

         The Corporation will bear all costs in connection with the solicitation
of proxies, including the cost of preparing, printing and mailing this Proxy
Statement. In addition to the use of the mails, proxies may be solicited by the
Corporation's directors, officers or employees. None of these individuals will
be additionally compensated, but they may be reimbursed for out-of-pocket
expenses in connection with the solicitation. Arrangements will also be made
with brokerage houses, banks or other custodians, nominees and fiduciaries for
the forwarding of solicitation material to the beneficial owners of the Shares
held of record by those persons, and the Corporation may reimburse these
custodians, nominees and fiduciaries for their reasonable out-of-pocket expenses
incurred in connection therewith.

         Shares represented by properly executed proxies in the accompanying
form received by the Board prior to the Annual Meeting will be voted at the
Annual Meeting. Shares not represented by properly executed proxies will not be
voted. If a Stockholder specifies a choice with respect to any matter to be
acted upon, the Shares represented by that proxy will be voted as specified. If
the Stockholder does not specify a choice, in an otherwise properly executed
proxy, with respect to any proposal referred to therein, the Shares represented
by that proxy will be voted with respect to that proposal in accordance with the
recommendations of the Board described herein. A Stockholder who signs and
returns a proxy in the accompanying form may revoke it by: (i) giving written
notice of revocation to the Corporation before the proxy is voted at the Annual
Meeting; (ii) executing and delivering a later-dated proxy; or (iii) attending
the Annual Meeting and voting the Shares in person.

         The close of business on October 27, 1998 has been fixed as the date
for determining those Stockholders entitled to notice of and to vote at the
Annual Meeting (the "Record Date"). On the Record Date, the Corporation had
139,850,839 shares of Common Stock and 2,500 shares of Class A Preferred Stock
outstanding. The Corporation has also authorized Class B 8% Preferred Stock, par
value $.00001 per share (the "Class B Preferred Shares"), and Class C Preferred
Stock, par value $.00001 per share (the "Class C Preferred Shares"). Presently,
there are no outstanding Class B or Class C Preferred Shares. The Common Stock
and the Class A Preferred Stock entitle the holders thereof to one vote per
share and 1,000 votes per


                                        1

<PAGE>   4



share, respectively, at the Annual Meeting. Only Stockholders of record as of
the Record Date will be entitled to vote at the Annual Meeting. The presence of
a majority of the total amount of votes allocable to outstanding shares of
Common Stock and Class A Preferred Stock, represented in person or by proxy at
the Annual Meeting, will constitute a quorum. If a quorum is present and a
majority of the votes are cast in favor of the nominees, they will be elected
directors of the Corporation. Accordingly, abstentions and broker non-votes will
not affect the outcome of the election. All other matters to be voted on will be
decided by the affirmative vote of a majority of the Shares present or
represented at the Meeting and entitled to vote. On any such matter, an
abstention will have the same effect as a negative vote and Shares held by
brokers will not be considered entitled to vote on matters as to which the
brokers have not received authority to vote from beneficial owners.


         SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

         The following table sets forth certain information regarding the
beneficial ownership of the total voting stock (including the Common Shares and
the Class A Preferred Shares) as of October 15, 1998 by: (i) each Stockholder
known by the Corporation to beneficially own in excess of 5% of the outstanding
Common Shares or Class A Preferred Shares; (ii) each director and director
nominee; and (iii) all directors, director nominees and executive officers, as a
group. All of the outstanding Class A Preferred Shares are owned by Dr. Ramesh
C. Pandey. Except as otherwise indicated in the footnotes to the table, the
persons named below have sole voting and investment power with respect to the
shares beneficially owned by such persons.


<TABLE>
<CAPTION>
- ---------------------------------------------------------------------------------------------------------------------
                                                                         CLASS A PREFERRED
                                          COMMON STOCK                         STOCK
- ---------------------------------------------------------------------------------------------------------------------
                                     NUMBER OF        PERCENT           NUMBER OF      PERCENT        PERCENT OF
NAME AND ADDRESS                      SHARES         OF CLASS            SHARES       OF  CLASS     VOTING STOCK (1)
- ---------------------------------------------------------------------------------------------------------------------
<S>                                <C>                 <C>              <C>          <C>            <C>  
The Edward A. Blech Trust (2)      40,300,000 (3)      28.8%                 0           -              28.3%
- ---------------------------------------------------------------------------------------------------------------------
David Blech (4)                    47,980,000 (3)(5)   34.3%                 0           -              33.7%
- ---------------------------------------------------------------------------------------------------------------------
Michael G. Jesselson (6) (7)       15,050,000 (8)      10.8%                 0           -              10.6%
- ---------------------------------------------------------------------------------------------------------------------
EER Systems (9)                        20,000,000      14.3%                 0           -              14.0%
- ---------------------------------------------------------------------------------------------------------------------
Dr. Paul Plattner (10)                  7,000,000       5.0%                 0           -               4.9%
- ---------------------------------------------------------------------------------------------------------------------
Dr. Ramesh C. Pandey (11)         22,164,545 (12)      15.8%             2,500          100%            17.3%
- ---------------------------------------------------------------------------------------------------------------------
All directors and executive       22,178,345 (13)      15.9%             2,500          100%            17.3%
officers as a group ....(two
persons)
- ---------------------------------------------------------------------------------------------------------------------
</TABLE>


(1)  Gives effect to the voting rights of 2,500 Class A Preferred Shares,  all 
     of which are owned by Dr. Pandey and which entitle him to cast 1,000 votes
     per share on all matters as to which Stockholders are entitled to vote.

(2)  The address of The Edward A. Blech Trust is 418 Avenue I, Brooklyn, 
     New York 11230.

(3)  As reported in a Schedule 13D filed jointly by Mr. Blech and The Edward A. 
     Blech Trust.

(4)  The address of Mr. Blech is 6th Floor, 94 Mercer Street, New York, New York
     10012.

(5)  Includes Common Shares owned by The Edward A. Blech Trust, Common Shares 
     owned by Mr. Blech as Custodian for Edward A. Blech and Common Shares owned
     by Mr. Blech's spouse.

(6)  Michael Jesselson, whose address is 1301 Avenue of the Americas, Suite 
     4101, New York, New York 10019, is Trustee for each of The Michael G.
     Jesselson 12/18/80 Trust, The Benjamin J. Jesselson 12/18/80 Trust and The
     Jesselson Grandchildren 12/18/80 Trust.


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<PAGE>   5



(7)  As reported in a Form 3.

(8)  Includes shares owned by the Michael G. Jesselson 12/18/80 Trust, The 
     Benjamin J. Jesselson 12/18/80 Trust and The Jesselson Grandchildren
     12/18/80 Trust .

(9)  As reported in a Schedule 13D and whose address is 10289 Aerospace Road, 
     Seabrook, MD 20706.

(10) As reported in a Schedule 13D and whose address is 2300 North Vermilion 
     Street, Danville, IL 61832.

(11) The address of Dr. Pandey is c/o Xechem International, Inc., 100 Jersey 
     Avenue, Building B, Suite 310, New Brunswick, New Jersey 08901.

(12) Does not include 707,000 Common Shares subject to certain options owned by 
     Dr. Pandey, which presently are not exercisable, and will not be
     exercisable, within 60 days from October 15, 1998.

(13) Includes 14,000 Common Shares subject to options which are exercisable 
     within 60 days from October 15, 1998

*     Less than one percent.

         On November 18, 1996, the Corporation entered into and closed the
initial stock issuances set forth in a Stock Purchase Agreement among the
Corporation, David Blech and Dr. Ramesh C. Pandey (the "Blech Purchase
Agreement") dated November 18, 1996, wherein the Corporation agreed to issue up
to a total of 110,000,000 Common Shares to David Blech or his designee. See
"Certain Relationships and Related Transactions." Additional issuances under the
Blech Purchase Agreement were closed at various dates through February 22, 1998.
As a result of such issuances, Mr. Blech has the ability to control the election
of the Board of Directors, as well as a contractual right to have his nominees
elected to the Board. Accordingly, Mr. Blech has obtained the power to control
the affairs of the Corporation. The Corporation is not aware of any other
arrangements, the operation of which may at a subsequent date, result in a
change of control of the Corporation.

                    MATTERS TO BE CONSIDERED BY STOCKHOLDERS

1.       ELECTION OF DIRECTORS

         Two individuals will be elected at the Annual Meeting to serve as
directors of the Corporation until the next annual meeting of stockholders or
otherwise as provided in the By-Laws. The Board of Directors has no reason to
believe that the nominees named will be unable to serve, if elected.

         The nominees for director are as follows:

         Ramesh C. Pandey, Ph.D., age 59, is the founder of the Corporation. He
has been Chief Executive Officer and President and a director of the
Corporation's subsidiary, Xechem, Inc. (the "Subsidiary"), since its formation
in 1990 and the Chief Executive Officer, President, and Chairman of the Board of
Directors of the Corporation since its formation in February 1994. From 1984 to
March 1990, Dr. Pandey was the President and Chief Scientist of the
Corporation's predecessor, Xechem Inc., formerly a subsidiary of
Fujisawa/LyphoMed, Inc. Dr. Pandey served as a visiting Professor at the Waksman
Institute of Microbiology at Rutgers University from 1984 to 1986. Dr. Pandey
has also served as scientist, consultant, and research associate for several
universities and private laboratories. Dr. Pandey has published numerous
articles in professional publications, such as the Journal of Antibiotics, the
Journal of the American Chemical Society and the Journal of Industrial
Microbiology. Dr. Pandey is a member of the editorial board of the Journal of
Antibiotics and of several professional societies.

         Stephen F. Burg, age 61, since 1986 has been chief executive officer of
El Dorado Investments, which offers corporate growth strategies for public and
private companies, nationally and internationally.


                                        3

<PAGE>   6



From 1978 to 1986, Mr. Burg was Vice President-Corporate Acquisitions for Evans
Products Company and from 1973 to 1978 was Corporate Director-Acquisitions and
Human Services for Jack August Enterprises.

         The Corporation's By-Laws do not require that the directors meet any
specific number of times during the year. Such meetings may be held either in
person or by telephonic conference. The Board met six times during the year
ended December 31, 1997.

         The Board has an audit committee presently consisting of Dr. Pandey
which was formed on May 26, 1995. The audit committee reviews with the
Corporation's independent public accountants the scope and timing of their audit
services and any other services they are asked to perform, the accountants
report on the Corporation's financial statements following completion of their
audit and the Corporation's policies and procedures with respect to internal
accounting and financial controls. In addition, the audit committee makes annual
recommendations to the Board for the appointment of independent accountants for
the ensuing year.

         The audit committee held one meeting during the year ended December 31,
1997.

         The Board has a stock option committee presently consisting of Dr.
Pandey which was formed on May 26, 1995. The stock option committee administers
the Xechem International, Inc. Amended and Restated Stock Option Plan (the
"Plan") and reviews and recommends to the Board stock options to be granted.

         The stock option committee held one meeting during the year ended
December 31, 1997.

         The Board has a compensation committee presently consisting of Dr.
Pandey which was formed on May 26, 1995. The compensation committee reviews and
recommends to the Board the compensation and benefits of all officers of the
Corporation and reviews general policy matters relating to compensation and
benefits of employees of the Corporation.

         Section 16(a) of the Securities Exchange Act of 1934, as amended,
requires the Corporation's officers and directors and persons who own more than
ten percent of a registered class of the Corporation's equity securities, to
file initial statements of beneficial ownership (Form 3), and statements of
changes in beneficial ownership (Forms 4 or 5), of Common Shares and other
equity securities of the Corporation with the U.S. Securities and Exchange
Commission (the "SEC"). The SEC requires officers, directors and greater than
ten percent stockholders to furnish the Corporation with copies of all these
forms filed with the SEC.

         To the Corporation's knowledge, based solely on its review of the
copies of these forms received by it, or written representations from certain
reporting persons that no additional forms were required for those persons, the
Corporation believes that all filing requirements applicable to its officers,
directors, and greater than ten percent beneficial owners were complied with.

         The two nominees receiving the highest vote totals will be elected
directors of the Corporation. Accordingly, abstentions and broker non-votes will
not affect the outcome of the election.

2.       APPROVAL OF AN AMENDMENT TO THE CORPORATION'S CERTIFICATE OF
         INCORPORATION TO REFLECT A ONE SHARE FOR 75 SHARES REVERSE SPLIT OF THE
         CORPORATION'S COMMON SHARES.

         The Board of Directors of the Corporation has approved a proposal to
effect a reverse stock split of the Corporation's Common Shares of one share for
each 75 shares previously issued and outstanding (the "Reverse Stock Split").
Except as may result from the payment of cash for fractional shares as described


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<PAGE>   7



below, each Stockholder will hold the same percentage of Common Shares
outstanding immediately following the Reverse Stock split as each Stockholder
did immediately prior to the Reverse Stock Split. If approved by the
Stockholders as provided herein, the Reverse Stock Split will be effected by an
amendment to the Corporation's Certificate of Incorporation in substantially the
form attached to this Proxy Statement as Appendix A (the "Reverse Stock Split
Amendment"), and will become effective upon the filing of the Reverse Stock
Split Amendment with the Secretary of State of Delaware (the "Effective Time").
The following discussion is qualified in its entirety by the full text of the
Reverse Stock Split Amendment, which is hereby incorporated by reference herein.

         At the Effective Time, each Common Share issued and outstanding will
automatically be reclassified and converted into one seventy-fifth of a Common
Share. Outstanding Class A Preferred Shares have not been specifically included
in the Reverse Stock Split Proposal because their conversion rate into Common
Shares automatically adjusts to reflect the Reverse Stock Split.

         Fractional Common Shares will not be issued as a result of the Reverse
Stock Split. Stockholders entitled to receive a fractional Common Share as a
consequence of the Reverse Stock Split will, instead, receive from the Company a
cash payment in U.S. dollars determined by multiplying such fraction by 75 times
the average closing price of the Common Shares on the OTC Bulletin Board for the
five trading days immediately preceding the effective date of the Amendment to
the Corporation's Certificate of Incorporation authorizing the Reverse Split.

         The Company expects that, if the Reverse Stock Split Proposal is
approved by the Stockholders at the Meeting, the Reverse Stock Split Amendment
will be filed promptly.

Reasons for the Reverse Stock Split

         The primary purpose of the Reverse Stock Split is to combine the
outstanding Common Shares so that the Common Shares outstanding after giving
effect to the Reverse Stock Split trade at a significantly higher price per
share than the Common Shares outstanding before giving effect to the Reverse
Stock Split.

         From January 1, 1998 to September 30, 1998, the closing bid price for
the Common Shares on the OTC Bulletin Board ranged from $0.72 to $0.09 per
share. The closing bid price for the Common Shares on October 20, 1998, was $.05
per share.

         The Corporation believes that such a low quoted market price per share
may discourage potential new investors, increase market price volatility and
decrease the liquidity of the Common Shares.

         The Corporation also believes that the current per share price level of
the Common Shares has reduced the effective marketability of the Common Shares
because of the reluctance of many brokerage firms to recommend low priced stock
to their clients. Certain investors view low-priced stock as unattractive,
although certain other investors may be attracted to low-priced stock because of
the greater trading volatility sometimes associated with such securities. In
addition, a variety of brokerage house policies and practices tend to discourage
individual brokers within those firms from dealing in low priced stock. Some of
those policies and practices pertain to the payment of brokers commissions and
to time-consuming procedures that function to make the handling of low priced
stocks unattractive to brokers from an economic standpoint.

         In addition, since brokerage commissions on low-priced stock generally
represent a higher percentage of the stock price than commissions on higher
priced stock, the current share price of the


                                        5

<PAGE>   8



Common Shares can result in individual Stockholders paying transaction costs
(commission, markups, or markdowns) which are a higher percentage of their total
share value than would be the case if the share price were substantially higher.
This factor also may limit the willingness of institutions to purchase the
Common Shares at their current low share price.

         The Common Shares presently are considered "penny stock" under the
Securities Exchange Act of 1934, as amended (the "Exchange Act"). The Exchange
Act imposes certain obligations on brokerage firms engaging in transactions
involving penny stock, including providing additional disclosure to investors
and obtaining certain written representations from such investors. These
additional obligations result in many brokerage firms declining to engage in
transactions involving penny stock.

         For all the above reasons, the Corporation believes that the Reverse
Stock Split is in the best interests of the Corporation and its Stockholders.
However, there can be no assurances that the Reverse Stock Split will have the
desired consequences. The Corporation anticipates that, following the
consummation of the Reverse Stock Split, the Common Shares will trade at a price
per share that is significantly higher than the current market price of the
Common Shares. However, there can be no assurance that, following the Reverse
Stock Split, the Common Shares will trade at seventy-five times the market price
of the Common Shares prior to the Reverse Stock Split.

Effect of the Reverse Stock Split Proposal

         Subject to Stockholder approval, the Reverse Stock Split Proposal will
be effected by filing the Reverse Stock Split Amendment to the Corporation's
Certificate of Incorporation, and will be effective immediately upon such
filing. Although the Corporation expects to file the Reverse Stock Split
Amendment with the Delaware Secretary of State's office promptly following
approval of the Reverse Stock Split Proposal at the Meeting, the actual timing
of such filing will be determined by the Corporation's management based upon
their evaluation as to when such action will be most advantageous to the
Corporation and its Stockholders.

         Each Stockholder that owns fewer than 75 Common Shares or who, as a
result of the Reverse Split will own a number of whole Common Shares plus a
fractional Common Share will have such Stockholder's fractional Common Shares
converted into the right to receive cash as set forth below in "Exchange of
Stock Certificates and Payment for Fractional Shares." The interest of such
Stockholder in the Corporation will thereby be terminated and such Stockholder
will have no right to share in the assets or future growth of the Corporation.
Each Stockholder that owns 75 or more Common Shares will continue to own Common
Shares and will continue to share in the assets and future growth of the
Corporation as a Stockholder. Such interest will be represented by one
seventy-fifth as many shares as such Stockholder owned before the Reverse Stock
Split, subject to the adjustment for fractional shares in which case such
Stockholder shall receive cash in lieu of such fractional share. The number of
Common Shares that may be purchased upon the exercise of outstanding options,
warrants and other securities convertible into, or exercisable or exchangeable
for, Common Shares, including the Class A Preferred Shares (collectively,
"Convertible Securities") and the per share exercise or conversion prices
thereof, will be adjusted appropriately as of the Effective Date, so that the
aggregate number of Common Shares issuable in respect of Convertible Securities
immediately following the Effective Date will be one seventy-fifth of the number
issuable in respect thereof immediately prior to the Effective Date, and the
aggregate exercise or conversion prices thereunder shall remain unchanged.

         The Reverse Stock Split will also result in some Stockholders owning
"odd lots" of less than 100 Common Shares received as a result of the Reverse
Stock Split. Brokerage commissions and other costs of


                                        6

<PAGE>   9



transactions in odd lots may be higher, particularly on a per-share basis, than
the cost of transactions in even multiples of 100 shares.

         The Corporation is authorized to issue 247,000,000 Common Shares, of
which 139,850,839 shares were issued and outstanding at the close of business on
the Record Date. The Corporation is also authorized to issue 3,000,000 shares of
Preferred Stock $.00001 par value (the "Preferred Stock"), of which 2,500 were
designated Class A Preferred Shares, with 2,500 issued and outstanding at the
close of business on the Record Date. The Reverse Stock Split will not effect
the amount of the Corporation's authorized Common Shares and Preferred Shares.
The number of outstanding Class A Preferred Shares will not be changed by the
Reverse Stock Split Proposal because their conversion rate into Common Shares
automatically adjusts to reflect the Reverse Stock Split.

         As of October 15, 1998, the Corporation had approximately 184 record
holders of Common Shares and one holder of Class A Preferred Shares and
believes, based on information received from the transfer agent and those
brokerage firms that hold the Corporation's securities in custodial or "street"
name, that such shares were beneficially owned by an aggregate of approximately
1,200 beneficial owners of Common Shares and one beneficial owner of Class A
Preferred Shares. Based on estimated stock holdings as of October 15, 1998, the
Corporation estimates that, after the Reverse Stock Split, the Corporation will
continue to have approximately the same number of Stockholders. EXCEPT FOR THE
RECEIPT OF CASH IN LIEU OF FRACTIONAL SHARES, THE REVERSE STOCK SPLIT WILL NOT
AFFECT ANY STOCKHOLDER'S PROPORTIONATE EQUITY INTEREST IN THE CORPORATION.

         The par value of the Common Shares will remain at $.00001 per share
following the Reverse Stock Split, and the number of Common Shares outstanding
will be reduced. As a consequence, the aggregate par value of the outstanding
Common Shares will be reduced, while the aggregate capital in excess of par
value attributable to the outstanding Common Shares for statutory and accounting
purposes will be correspondingly increased. The Reverse Stock Split will not
affect the Corporation's retained earnings deficit, and stockholders' equity
will remain substantially unchanged.

         Effectuation of the Reverse Stock Split Proposal as of December 31,
1997 would not have had an effect on the Corporation's $5.28 million
consolidated net loss for the twelve month period then ended. However, net loss
per share of $.06 would have been proportionately increased to approximately
$4.25. No adjustment has been made for the reduction in the number of Common
Shares resulting from the payment of cash for fractional shares. If the Reverse
Stock Split Proposal is effected, the per share information included in
consolidated financial statements and other publicly available information of
the Corporation would be restated following the Effective Date to reflect the
Reverse Stock Split.

Exchange of Stock Certificates and Payment for Fractional Shares

         The combination and reclassification of Common Shares pursuant to the
Reverse Stock Split will occur automatically on the Effective Date without any
action on the part of Stockholders and without regard to the date certificates
representing Common Shares prior to the Reverse Stock Split are physically
surrendered for new certificates. If the number of Common Shares to which a
holder is entitled as a result of the Reverse Stock Split would otherwise
include a fraction, the Corporation will pay to the Stockholder, in lieu of
issuing fractional shares of the Corporation, cash in an amount equal to the
same fraction multiplied by 75 times the average closing price of the Common
Shares on the OTC Bulletin Board for the five trading days immediately preceding
the Effective Date.


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<PAGE>   10



         As soon as practicable after the Effective Date, transmittal forms will
be mailed to each holder of record of certificates for Common Shares to be used
in forwarding such certificates for surrender and exchange for certificates
representing the number of Common Shares such Stockholder is entitled to receive
as a consequence of the Reverse Stock Split. The transmittal forms will be
accompanied by instructions specifying other details of the exchange. Upon
receipt of such transmittal form, each Stockholder should surrender the
certificates representing Common Shares prior to the Reverse Stock Split, in
accordance with the applicable instructions. Each holder who surrenders
certificates will receive new certificates representing the whole number of
Common Shares that he holds as a result of the Reverse Stock Split and any cash
payable in lieu of a fractional share. STOCKHOLDERS SHOULD NOT SEND THEIR STOCK
CERTIFICATES UNTIL THEY RECEIVE A TRANSMITTAL FORM.

         After the Effective Date, each certificate representing Common Shares
outstanding prior to the Effective Date (an "old certificate") will, until
surrendered and exchanged as described above, be deemed, for all corporate
purposes, to evidence ownership of the whole number of Common Shares, and the
right to receive from the Corporation the amount of cash for any fractional
shares, into which the Common Shares evidenced by such certificate have been
converted by the Reverse Stock Split, except that the holder of such unexchanged
certificates will not be entitled to receive any dividends or other
distributions payable by the Corporation after the Effective Date, until the old
certificates have been surrendered. Such dividends and distributions, if any,
will be accumulated, and at the time of surrender of the old certificates, all
such unpaid dividends or distributions will be paid without interest.

Federal Income Tax Consequences

         The following discussion describes the material federal income tax
consequences of the Reverse Stock Split. This discussion is based upon the
Internal Revenue Code of 1986 (the "Code"), existing and proposed regulations
thereunder, reports of congressional committees, judicial decisions, and current
administrative rulings and practices, all as amended and in effect on the date
hereof. Any of these authorities could be repealed, overruled, or modified at
any time. Any such change could be retroactive and, accordingly, could cause the
tax consequences to vary substantially from the consequences described herein.
No ruling from the Internal Revenue Service (the "IRS") with respect to the
matters discussed herein has been requested, and there is no assurance that the
IRS would agree with the conclusions set forth in this discussion. All
Stockholders should consult with their own tax advisors.

         This discussion may not address certain federal income tax consequences
that may be relevant to particular Stockholders in light of their personal
circumstances or to certain types of Stockholders (such as dealers in
securities, insurance companies, foreign individuals and entities, financial
institutions, and tax-exempt entities) who may be subject to special treatment
under the federal income tax laws. This discussion also does not address any tax
consequences under state, local or foreign laws.

         STOCKHOLDERS ARE URGED TO CONSULT THEIR TAX ADVISERS AS TO THE
PARTICULAR TAX CONSEQUENCES TO THEM OF THE REVERSE SPLIT, INCLUDING THE
APPLICABILITY OF ANY STATE, LOCAL, OR FOREIGN TAX LAWS, CHANGES IN APPLICABLE
TAX LAWS, AND ANY PENDING OR PROPOSED LEGISLATION.

         The Company should not recognize any gain or loss as a result of the
Reverse Stock Split. No gain or loss should be recognized by a Stockholder who
receives only Common Shares upon the Reverse Stock Split. A Stockholder who
receives cash in lieu of a fractional Common Share that otherwise would be held
as a capital asset generally should recognize capital gain or loss on an amount
equal to the difference between the cash received and his basis in such
fractional share of Common Share. For this purpose, a


                                        8

<PAGE>   11



Stockholder's basis in such fractional share of Common Stock will be determined
as if the Stockholder actually received such fractional share. Except as
provided with respect to fractional shares, the aggregate tax basis of the
Common Shares held by a Stockholder following the Reverse Stock Split will equal
the Stockholder's aggregate basis in the Common Share held immediately prior to
the Reverse Stock Split and generally will be allocated among the Common Shares
held following the Reverse Stock Split on a pro-rata basis. Stockholders who
have used the specific identification method to identify their basis in Common
Shares combined in the Reverse Stock Split should consult their own tax advisors
to determine their basis in the post-Reverse Stock Split Common Shares received
in exchange therefor.

3.       APPROVAL OF AN INCREASE IN THE NUMBER OF COMMON SHARES WHICH MAY BE
         ISSUED UNDER THE XECHEM INTERNATIONAL, INC. AMENDED AND RESTATED STOCK 
         OPTION PLAN

         The Plan amends and restates the 1993 Xechem, Inc. Stock Option and
Incentive Plan, the obligations under which the Corporation assumed as part of
the Corporation's organization and prior to its April 26, 1994 public offering.
The purpose of the Plan is to encourage ownership of Common Shares by the
Corporation's key employees, non-employee directors and advisors, including
members of the Corporation's Scientific Adversary Board, in order to attract
such persons, to induce such persons to remain in the employ of the Corporation
or its affiliates, or to serve as an advisor to the Corporation, and to provide
additional compensation for such persons to promote the success of the
Corporation or its affiliates. Key employees include employees who are also
officers or directors of the Corporation or its affiliates.

         The decision to grant options to these individuals is intended to
reward them for their services to the Corporation without burdening the
Corporation with significant increases in direct compensation. Since its
inception, the Corporation's directors, key employees and advisors have been
endeavoring to reach the Corporation's objectives of developing a more efficient
drug discovery process and niche generic drugs, as well as commercializing and
marketing such drugs. Through their efforts, the Corporation believes that
significant progress has been made toward these objectives. The Board believes
that the ability to achieve these objectives is best served by the alignment of
the financial success of the Corporation's directors and key employees with that
of its Stockholders.

         Stockholder approval of this amendment to the Plan is sought to
continue to qualify the Plan under Rule 16b-3 of the Exchange Act and thereby
render certain pre-split transactions under the Plan exempt from certain
provisions of Section 16 of the Exchange Act.

         As of the date of this Proxy Statement, the Corporation has granted
options for 1,692,000 Common Shares available for issuance under the Plan. The
Board has authorized an increase of 10,000,000 Common Shares for issuance under
the Plan, for a total of 12,600,000 shares. The Board believes that it is in the
best interests of the Corporation and the Stockholders to increase the number of
Common Shares which may be issued under the Plan in order to continue to attract
key persons to the Corporation and reward them for their efforts. With the
exception of increasing the number of Common Shares which may be issued under
the Plan, the Board is not seeking Stockholder approval of any other provisions
of the Plan.

General

         The Plan grants the Board authority to issue options to purchase up to
2,600,000 (to be increased to 12,600,000) Common Shares and any other stock or
security resulting from adjustments or substitutions as described in the Plan.
Common Shares will be reserved and available for purchase upon the exercise of
options granted under the Plan.


                                        9

<PAGE>   12



         The Plan provides for the issuance of incentive options under Section
422 of the Internal Revenue Code of 1986, as amended (the "Code"), and
nonstatutory options which are not intended to be incentive stock options under
Section 422 of the Code. The decision as to whether incentive options or
nonstatutory options will be issued to recipients is solely within the
discretion of the Board. The Board will administer the Plan and have the
authority to determine, among other things, the individuals to be granted
incentive options or nonstatutory options, the exercise price at which the
Common Shares may be acquired, the number of Common Shares subject to each
option and the exercise period of each option. The Board will also be authorized
to construe and interpret the Plan and to prescribe additional terms and
conditions of exercise in option agreements and provide the form of option
agreement to be utilized with the Plan.

         Incentive options terminate not more than ten years from the date of
grant; however, such options terminate not more than five years from the date of
grant if such options are required to have an exercise price of at least 110% of
fair market value. Nonstatutory options terminate not more than eleven years
from the date of grant.

         Options will not be transferable except by will or by the laws of
descent and distribution, and are exercisable during an optionee's lifetime only
by the optionee or the appointed guardian or legal representative of the
optionee. Upon the (i) death or permanent and total disability of an optionee,
or (ii) termination of employment with the Corporation, then any unexercised
options to acquire Common Shares will be exercisable at any time within six
months in the case of (i) and 30 days in the case of (ii) (but in no case beyond
the expiration date specified in the option agreement).

         The Plan requires the optionee to pay, at the time of exercise, for all
shares acquired on exercise in cash, Common Shares or other forms of
consideration acceptable to the Board.

         If the Corporation declares a stock dividend, splits its stock,
combines or exchanges its Common Shares, or engages in any other transactions
which result in a change in capital structure, such as a merger, consolidation,
dissolution, liquidation or similar transaction, the Board may adjust or
substitute, as the case may be, the number of Common Shares available for
issuance upon exercise of options granted under the Plan, the number of shares
covered by outstanding options, the exercise price per share of outstanding
options, any target price levels for vesting of the options and any other
characteristics of the options as the Board deems necessary to equitably reflect
the effects of those changes on the option holders.

         The Corporation has granted options for a total of 1,692,000 Common
Shares under the Plan. Included in the count are options to purchase 318,500
Common Shares granted to former directors and a former executive officer of the
Corporation and options to purchase 851,500 Common Shares granted to current and
former employees of the Corporation.

         Pursuant to the terms of the grants, the options for shares granted
under the Plan vest and are exercisable in installments as follows: (i) to the
extent of 20% of the number of Common Shares, commencing on the first
anniversary of the date of grant; and (ii) to the remaining 80% of Common
Shares, an additional 20% commencing on each of the second through the fifth
anniversary of the date of grant.

Discussion of Federal Income Tax Consequences

         The following summary of tax consequences is not comprehensive and is
based on laws and regulations in effect on October 15, 1998. These laws and
regulations are subject to change on a retroactive basis.


                                       10

<PAGE>   13



         The grant of a nonqualified option under the Plan is not a taxable
event and the Corporation is not entitled to a deduction upon such grant. Upon
exercise of a nonqualified option, participants will be taxed at ordinary income
rates on the difference between the exercise price of the option and the fair
market value of the Common Shares issued pursuant to such exercise. Fair market
value generally will be determined on the date of exercise (or in the case where
a sale of property could subject a transferor to suit under Section 16(b) of the
Securities Exchange Act of 1934, the later of the date of exercise and the date
which is six months and one day after the date on which the option was granted,
unless the participant elects to be taxed based on the fair market value at the
date of exercise). The Corporation will receive a corresponding deduction for
the amount of income recognized by a participant upon exercise of an option in
the same year the participant recognizes income in connection with the exercise
of an option. The participant, generally, will have a tax basis for the Common
Shares acquired equal to the fair market value of the Common Shares at the date
of exercise. Any gain or loss realized upon the subsequent sale of the Common
Shares issued upon exercise of a nonqualified option will be taxed at either
long-term or short-term capital gain (or loss) rates, depending on the selling
stockholder's holding period. The subsequent sale would have no tax consequences
for the Corporation.

         The recipient of an incentive stock option generally will not recognize
any income upon its grant or upon its exercise if no disposition of the Common
Shares received upon exercise is made within two years from the date of grant or
within one year after the acquisition of the Common Shares. The excess of the
fair market value of the Common Shares over the exercise price of the Common
Shares received upon the exercise of an incentive stock option, however, is a
tax preference item in the year of exercise which may subject the recipient to
an alternative minimum tax. Upon a subsequent sale of Common Shares acquired
pursuant to exercise of an incentive stock option, if the foregoing holding
periods are met, the recipient will recognize a long-term capital gain upon the
difference between the sale price and the exercise price, and the Corporation
will receive no deduction from taxable income. If these holding periods are not
met, the recipient generally will realize ordinary income to the extent of the
difference between the exercise price and the fair market value of the Common
Shares on the date the option is exercised. However, if the disposition is by a
sale or exchange at a price less than the fair market value of the Common Shares
on the date of exercise, then, in general, the amount of ordinary income is
limited to the gain recognized on such sale or exchange. If the sale price
exceeds the fair market value of the Common Shares on the date of exercise, such
excess will be a long-term or short-term capital gain, depending on the
employee's holding period for the Common Shares being sold. The Corporation will
have a deduction in an amount equal to the ordinary income recognized by the
optionee.

4.       SELECTION OF INDEPENDENT AUDITOR

         The Corporation's financial statements, including those for the fiscal
year ended December 31, 1997, are included in the Annual Report furnished to all
Stockholders. The year-end statements have been audited by the independent firm
of Moore Stephens P.C. (formerly known as Mortenson and Associates, P.C.) which
has served as the Corporation's independent auditor since its formation in
February 1994. The total fees paid or accrued to Moore Stephens P.C. in
connection with the 1997 audit were approximately $20,000. The Board believes
that Moore Stephens P.C. is knowledgeable about the Corporation's operations and
accounting practices and is well qualified to act in the capacity of independent
auditor. Therefore, the Board has selected Moore Stephens P.C. as the
Corporation's independent auditor to examine its financial statements for the
fiscal year ended December 31, 1998. Although the selection of an auditor does
not require a Stockholder vote, the Board believes it is desirable to obtain the
concurrence of the Stockholders to this selection. Due to the difficulty and
expense involved in retaining another independent firm on short notice, the
Board does not contemplate appointing another firm to act as the Corporation's
independent auditor for fiscal year 1998 if the Stockholders do not concur in
the appointment of Moore Stephens P.C.


                                       11

<PAGE>   14



Instead, the Board will consider the vote as advice in making its selection of
an independent auditor for the following year.

         Representatives of Moore Stephens P.C. are expected to be present at
the Meeting and will have the opportunity to make a statement, if they so
desire, and will be available to respond to appropriate questions.

                COMPENSATION OF DIRECTORS AND EXECUTIVE OFFICERS

A.       DIRECTOR COMPENSATION

         Directors serve without compensation for such services.

B.       EXECUTIVE COMPENSATION

         Set forth below is information concerning the compensation for 1995,
1996 and 1997 for the Corporation's President and Chief Executive Officer, who
is the only executive officer of the Corporation whose compensation exceeded
$100,000 during such years:

<TABLE>
<CAPTION>
- ------------------------------------------------------------------------------------------------------------------------------------
                                                                                  LONG TERM COMPENSATION
- ------------------------------------------------------------------------------------------------------------------------------------
                                                                                                                        ALL OTHER
                                    ANNUAL COMPENSATION                           AWARDS                PAYOUTS       COMPENSATION
- -----------------------------------------------------------------------------------------------------------------------------------
                                                                                        SECURITIES     LONG TERM
                                                             OTHER        RESTRICTED      UNDER-       INCENTIVE
                                                            ANNUAL          STOCK         LYING          PLAN
                       YEAR    SALARY        BONUS       COMPENSATION       AWARDS       OPTIONS        PAYOUTS
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                    <C>     <C>              <C>         <C>               <C>           <C>            <C>              <C>
Dr. Ramesh Pandey      1995    $139,525         0           $7,072            0             0              0                0
                       1996    $118,365         0           $13,375           0             0              0                0
                       1997    $130,273         0           $7,991            0             0              0                0
===========================  ============= ===========  ===============  ============  ============  =============  ================
</TABLE>

Employment Agreements.

         Ramesh C. Pandey is employed pursuant to an agreement which provides
for a base salary of $140,000 per year, subject to an annual increase in
proportion to the increase in the consumer price index, such bonuses as a
majority of the disinterested members of the Board of Directors may determine,
and a royalty of 2 1/2% of the Corporation's net profits before taxes with
respect to any products developed by the Corporation or its affiliates during
the term of the agreement. The royalty will be payable to Dr. Pandey or his
estate so long as the Corporation continues to sell such products,
notwithstanding any termination of the agreement. The agreement provides for a
ten year term, but permits either party to terminate the agreement after five
years; if the Corporation terminates the agreement, Dr. Pandey will be entitled
to receive severance equal to his compensation for the two years prior to
termination. Dr. Pandey has agreed not to engage in certain business activities
(generally similar to those currently engaged in by the Corporation) for six
months (four months, in certain cases) after the termination of his employment
with the Corporation. If there is a change in the beneficial ownership of 20% or
more of the Corporation's capital stock, Dr. Pandey may, at any time within one
year after such event, terminate the agreement, in which event his non-compete
and confidentiality agreement terminate and all indebtedness of the Corporation
to Dr. Pandey shall accelerate. Dr. Pandey has agreed and approved the
transactions contemplated by the Blech Purchase Agreement (see "Certain
Relationships and Related Transactions") and, accordingly, such transactions do
not and will not result in a "Change of Control" as defined in the Employment
Agreement. In August 1996, due to the


                                       12

<PAGE>   15



financial constraints of the Company, Dr. Pandey's salary was reduced by 54%. In
November 1996, 50% of the reduction was restored and in February 1997, Dr.
Pandey was returned to full salary. The reduction in salary was not accrued and
will not be paid to Dr. Pandey.

         The Corporation has granted an option to Dr. Pandey to purchase Common
Shares in an amount equal to 20% of the total number of shares of the
Corporation's stock sold in a recently concluded rights offering to certain
shareholders and one or more subsequent offerings to raise additional capital.
The exercise price for this option is 1/10,000 of $.01 per share and the option
is exercisable for ten years.

STOCK PLAN

         Effective December 1993, Xechem's sole stockholder approved the Share
Option Plan (the "Plan"), which the Corporation has assumed, providing for the
issuance to employees, consultants, and directors of options to purchase up to
2,600,000 Common Shares, which number of shares the Corporation is seeking to
increase to 12,600,000. The Plan provides for the grant to employees of
incentive stock options ("ISOs") and non-qualified stock options.

         The Plan is administered by a Stock Option Committee established in May
1995 and is presently comprised of one member of the Board of Directors which
has the power to determine eligibility to receive options and the terms of any
options granted, including the exercise or purchase price, the number of shares
subject to the options, the vesting schedule, and the exercise period. The
exercise price of all ISOs granted under the Plan must be at least equal to the
fair market value of the Common Shares on the date of grant. With respect to any
participant who owns stock possessing more than 10% of the voting power of the
Corporation's outstanding capital stock, the exercise price of any ISO granted
must equal at least 110% of the fair market value on the grant date and the
maximum exercise period of the ISO must not exceed five years. The exercise
period of any other options granted under the Plan may not exceed 11 years (10
years in the case of ISOs).

         The Plan will terminate in December 2003, ten years after the date it
was first approved by the Corporation's stockholders, though awards made prior
to termination may expire after that date, depending on when granted. As of
October 15, the Corporation has granted options under the Plan to purchase
1,692,000 Common Shares.

OPTION TABLES

         The following table sets forth certain information with respect to
options granted to the directors and executive officers of the Corporation
during the year ended December 31, 1997 under the Plan. The Corporation did not
grant any stock appreciation rights during the year.


<TABLE>
<CAPTION>
======================================================================================================
                                          Individual Grants
- ------------------------------------------------------------------------------------------------------
                       Number of Securities    % of Total Options        Exercise
                        Underlying Options    Granted to Employees      Price (per
        Name                 Granted             In Fiscal Year           Share)      Expiration Date
- ------------------------------------------------------------------------------------------------------
<S>                           <C>                      <C>                <C>             <C>   
Stephen Burg                  10,000                   .7%                $0.34           06/10/07
- ------------------------------------------------------------------------------------------------------
Stephen Burg                  50,000                  3.6%                $0.66           12/01/08
- ------------------------------------------------------------------------------------------------------
         TOTAL                60,000                  4.3%
======================================================================================================

</TABLE>


                                       13

<PAGE>   16



AGGREGATED OPTION EXERCISES IN FISCAL 1997 AND FISCAL YEAR-END OPTION VALUES

         The following table provides information on option exercises during the
year ended December 31, 1997 by the directors and executive officers of the
Corporation and the value of such parties' unexercised stock options as of
December 31, 1997.

<TABLE>
<CAPTION>
==============================================================================================================================
                                                                Number of Securities              Value of Unexercised
                                                               Underlying Unexercised             In-the-Money Options
                                                                 Options at 12/31/97                 at 12/31/97 (1)
- ------------------------------------------------------------------------------------------------------------------------------
                                Shares
                               Acquired        Value
           Name                   on          Realized     Exercisable      Unexercisable     Exercisable     Unexercisable
                               Exercise         ($)
                                  (#)
- -----------------------------------------------------------------------------------------------------------------------------
<S>                            <C>            <C>          <C>              <C>               <C>            <C>     
Dr. Ramesh C. Pandey               0             0              0            707,000(2)            0            $331,336
- -----------------------------------------------------------------------------------------------------------------------------
Stephen Burg                       0             0          1,000             64,000            $220                   0(3)
=============================================================================================================================
</TABLE>



(1)      Represents the excess, if any, of the closing price of the Common
         Shares as quoted on the OTC Bulletin Board on December 31, 1997 ($0.47)
         over the exercise price of the options, multiplied by the corresponding
         number of underlying shares.

(2)      These options were issued in exchange for the capital stock of the
         Subsidiary in the reorganization of the Corporation. These options are
         exercisable upon the Corporation attaining specific financial goals.

(3)      The net exercise price of the options exceeds the closing price of the 
         Common Shares on the OTC Bulletin Board on December 31, 1997.

                 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

         On April 25, 1994, Dr. Ramesh C. Pandey, the Corporation's Chairman of
the Board and Chief Executive Officer, exchanged the capital stock of Xechem,
Inc. for 2,800,000 of the Company's Common Shares, 2,500 Class A Preferred
Shares, and certain options. On the same date, Dr. Pandey exchanged $107,000 of
indebtedness of the Subsidiary for 1,070 Class B Preferred Shares and $517,451
of indebtedness of the Subsidiary (including accrued interest) for a note of the
Corporation in the same amount. Pursuant to the Blech Purchase Agreement, Dr.
Pandey subsequently exchanged such Class B Preferred Shares and the note for
other equity securities of the Corporation.

         Subject to obtaining necessary regulatory approvals in India, Dr.
Pandey has transferred his interest in Xechem India to the Corporation for no
consideration other than reimbursement of amounts (equal to approximately
$5,000) Dr. Pandey advanced for organizational expenses. Dr. Pandey's brothers
own the remaining equity in Xechem India, some or all of which the Corporation
anticipates will be made available to other, unrelated, persons in India. Both
of Dr. Pandey's brothers and Mr. Anil Sharma, a chartered accountant, serve as
directors of Xechem India. No compensation is paid to Dr. Pandey, his relatives
or Mr. Anil Sharma for service as directors.

         Effective June 25, 1996, an entity wholly-owned by Dr. Pandey (the
"Holding Company") became a member of Vineyard Productions, L.L.C. ("Vineyard"),
which in June 1994 acquired the building in which the Corporation leases its
offices. Prior to making such investment, Dr. Pandey informed the Board of
Directors of the opportunity for such investment, and the Board determined that
the Corporation was not


                                       14

<PAGE>   17



interested in such opportunity and approved Dr. Pandey making the investment.
The Corporation's lease was entered into prior to that date (with a prior owner
of the building) and has not been modified subsequent thereto. The Corporation
paid Vineyard $110,491 in 1996, including $21,705 subsequent to June 25, 1996,
and $130,258 in 1997.

         On November 18, 1996, the Corporation entered into and closed the
initial stage of a the Blech Purchase Agreement providing for the sale of up to
55,000 shares of Class C Series 2 Voting Cumulative Preferred Stock (the "Series
2 Preferred Shares") for a purchase price of $100 per share ($5,500,000 in the
aggregate), or the underlying Common Shares, over approximately nine months. At
the initial closing, The Edward A. Blech Trust (the "Trust") purchased 5,000
Series 2 Preferred Shares for $500,000. The Trust purchased an additional 5,000
Series 2 Preferred Shares on December 30, 1996; 5,000 Series 2 Preferred Shares
on January 8, 1997; and 7,500 Series 2 Preferred Shares on February 7, 1997. The
Blech Purchase Agreement was amended, effective March 27, 1997, to modify the
dates for closing of other purchases of portions of the shares issuable
thereunder. Pursuant to the Blech Purchase Agreement, on February 7, 1997, Dr.
Ramesh Pandey, the Company's Chairman and Chief Executive Officer, exchanged
certain indebtedness owed by the Corporation to him and the 1,070 Class B
Preferred Shares of the Corporation held by him for 12,144 shares of Class C
Series 3 Preferred Shares (the "Series 3 Preferred Shares"). Pursuant to their
terms, effective February 8, 1997, the then outstanding 22,500 Series 2
Preferred Shares and 12,144 Series 3 Preferred Shares were converted into
45,000,000 and 19,430,400 Common Shares, respectively. For the period March 28,
1997 through December 31, 1997, The Edward Blech Trust purchased 2,300,000
Common Shares and 15 other assignees purchased 48,320,000 Common Shares, which
included two affiliated individuals who purchased 1,960,000 Common Shares, two
trusts, not otherwise affiliated with Mr. Blech, each purchased 5,000,000 Common
Shares on March 27, 1997 and Mr. Blech purchased 5,000,000 Common Shares on
April 14, 1997. On May 1, 1997, Mr. Blech sold (at his cost) his 5,000,000
Common Shares to the two referenced unaffiliated trusts and a third unaffiliated
trust. To date, cash payments of $5,500,000 have been made under the Blech
Purchase Agreement and 110,000,000 Common Shares have been issued thereunder.

         Pursuant to the Blech Purchase Agreement, the Corporation, Dr. Pandey
and Mr. Blech have also entered into a stockholders' agreement, which, among
other things: (i) generally prohibits the sale of any of Dr. Pandey's shares of
capital stock of the Corporation for a period of five years, except with the
consent of Mr. Blech; (ii) provides Mr. Blech with the right to sell his pro
rata portion (relative to the holdings of Dr. Pandey) of any proposed sale of
shares by Dr. Pandey, and a reciprocal right in favor of Dr. Pandey to sell his
pro rata portion of any shares sold by Mr. Blech; (iii) requires Mr. Blech to
vote for Dr. Pandey as a director of the Corporation, and to use his efforts to
cause Dr. Pandey to remain Chairman, President and Chief Executive Officer of
the Corporation; (iv) requires the Corporation and its directors (subject to
their fiduciary duties to the Corporation and the Stockholders) to take such
actions as Mr. Blech may request to elect his nominees to constitute a majority
of the directors of the Corporation (to date, Mr. Blech has not exercised such
right); and (v) provides for certain demand and piggyback registration rights in
favor of Mr. Blech.

         The Corporation has received an opinion from The Griffing Group, Inc.,
an independent valuation and financial advisory firm, as to the fairness of the
above transactions, from a financial point of view, to the Stockholders.

         During 1997 and 1998, the Corporation made secured and unsecured loans
totaling $100,000 to Consumers Choice Systems, Inc. ("CCS"), a company engaged
in the marketing and distribution of products in the over-the-counter
pharmaceutical market. The Corporation has entered into negotiations with CCS in


                                       15

<PAGE>   18



connection with possible distribution of nutraceuticals of the Corporation's
subsidiary, XetaPharm, Inc. ("XetaPharm"). CCS is engaged in a private offering
of its securities and, upon completion of this offering, The Edward Blech Trust
would own approximately 30.8% of CCS's common stock.

         During 1998, the Corporation made six unsecured loans totaling $72,000
to Pacific Sensuals, Inc. ("Pacific"), a company engaged in the marketing and
distribution of products sold through health stores. The Corporation has entered
into negotiations with Pacific in connection with possible distribution of
XetaPharm nutraceuticals. David Blech, a principal Stockholder of the Company,
has an indirect 38% ownership interest in Pacific.

         During 1997 and 1998, the Corporation made four unsecured loans
totaling $144,000 to Margaret Chassman. Ms. Chassman is the wife of David Blech,
a principal Stockholder of the Corporation.

                              STOCKHOLDER PROPOSALS

         Stockholder proposals for the 1999 Annual Meeting of Stockholders must
be received by the Corporation at its executive office in New Brunswick, New
Jersey, on or prior to July 21, 1999 for inclusion in the Corporation's proxy
statement for that meeting. Any stockholder proposal must also meet the other
requirements for stockholder proposals as set forth in the rules of the U.S.
Securities and Exchange Commission relating to stockholder proposals.

                                  OTHER MATTERS

         As of the date of this Information Statement, no business, other than
that discussed above, is to be acted upon at the Meeting. If other matters not
known to the Board should, however, properly come before the Meeting, the
persons to whom the Majority Stockholders have given their consents and proxies
intend to vote in accordance with their best judgment.



                                          Xechem International, Inc.
                                          By the Order of the Board of Directors


                                          Ramesh C. Pandey, Ph.D.
                                          President and Chief Executive Officer


New Brunswick, New Jersey
November 19, 1998



                                       16

<PAGE>   19


         A COPY OF THE XECHEM INTERNATIONAL, INC. 1997 ANNUAL REPORT ON FORM
10-KSB FILED WITH THE U.S. SECURITIES AND EXCHANGE COMMISSION WILL BE SUPPLIED
TO STOCKHOLDERS WITHOUT CHARGE. REQUESTS FOR THE REPORT SHOULD BE DIRECTED TO:

                  Xechem International, Inc.
                  100 Jersey Avenue, Building B, Suite 310
                  New Brunswick, New Jersey  08901-3279


================================================================================
              YOUR VOTE IS IMPORTANT. THE PROMPT RETURN OF PROXIES
                WILL SAVE THE CORPORATION THE EXPENSE OF FURTHER
             REQUESTS FOR PROXIES. PLEASE PROMPTLY MARK, SIGN, DATE
             AND RETURN THE ENCLOSED PROXY IN THE ENCLOSED ENVELOPE.
================================================================================


                                       17

<PAGE>   20
                           XECHEM INTERNATIONAL, INC.
                    100 JERSEY AVENUE, BUILDING B, SUITE 310
                         NEW BRUNSWICK, NEW JERSEY 08901


          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS.

         The undersigned hereby appoints Dr. Ramesh C. Pandey and Stephen Burg,
and each of them, as Proxies, with the power to appoint their substitutes, and
hereby authorizes them to represent and to vote, as designated below, all the
Shares of Common Stock and Class A Preferred Stock of Xechem International, Inc.
(the "Corporation") held of record by the undersigned on October 27, 1998, at
the Annual Meeting of Stockholders when convened on December 11, 1998, or any
adjournment thereof.

THIS PROXY WHEN PROPERLY EXECUTED WILL BE VOTED IN THE MANNER DIRECTED HEREIN BY
THE UNDERSIGNED SHAREHOLDER. IF NO DIRECTION IS MADE, THIS PROXY WILL BE VOTED
FOR PROPOSALS 1, 2, 3, 4 AND 5.

                                      
                        CONTINUED ON THE REVERSE SIDE.


<PAGE>   21


X

   PLEASE MARK YOUR
   VOTES AS IN THIS
   EXAMPLE.



<TABLE>
<CAPTION>

<S>                  <C>        <C>              <C>

                     FOR        WITHHELD          PROPOSAL to elect two Directors to hold office until the next Annual Meeting
1. Election of       [ ]          [ ]             of Stockholders, or otherwise as provided in the Corporation's Certificate of
   Directors                                      Incorporation (check one box):
                                                  NOMINEES:    Dr. Ramesh C. Pandey
                                                               Stephen Burg

For, except vote withheld from the following nominee(s):


- ------------------------------------------------


                     FOR      AGAINST       ABSTAIN    PROPOSAL to amend the Certificate of Incorporation of Xechem 
2. Amend             [ ]        [ ]           [ ]      International, Inc. to reflect a one share for 75 shares reverse split of
   Certificate of                                      the outstanding Common Stock.
   Incorporation                                       
   
                     FOR      AGAINST       ABSTAIN    PROPOSAL to approve an increase in the number of shares of Common
3. Stock             [ ]        [ ]           [ ]      Stock which may be issued under the Xechem International, Inc. Amended
   Option Plan                                         and Restated Stock Option Plan(check one box).

                     FOR      AGAINST       ABSTAIN    PROPOSAL to concur in the selection of Mortenson and Associates, P.C. as
4. Select            [ ]        [ ]           [ ]      the Corporation's independent auditor for the fiscal year ending December 31,
   Auditor                                             1998 (check one box).

                     FOR      AGAINST       ABSTAIN    In their discretion, the Proxies are authorized to transact any other
                                                       business as may properly come before the Meeting, or any adjournment thereof.
5. Other             [ ]        [ ]           [ ]      
   Business

                                                       PLEASE PROMPTLY MARK, DATE, SIGN AND RETURN THIS CARD USING THE ENCLOSED
                                                       ENVELOPE.  PLEASE CONTACT DR. RAMESH C. PANDEY AT (732) 247-3300 WITH ANY
                                                       QUESTIONS REGARDING THE ABOVE.

</TABLE>



SIGNATURE(S)_____________________________________________ DATE__________________
NOTE:   Sign exactly as name appears above.  If joint tenant, both should sign.
        If attorney, executor, administrator, trustee or guardian, give full
        title as such. If a corporation, please sign corporate name by President
        or authorized officer. If partnership, sign in full partnership name by 
        authorized person.




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