XECHEM INTERNATIONAL INC
10QSB, EX-15, 2000-08-11
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                                                      Exhibit 15

Board of Directors
Xechem International, Inc.

          We have reviewed the accompanying consolidated balance sheet of Xechem
International,  Inc. and its  subsidiaries  as of June 30, 2000, and the related
consolidated  statements of operations,  stockholders' equity and cash flows for
the three-month and six-month periods then ended. These  consolidated  financial
statements are the responsibility of the Company's management

          We conducted our review in accordance  with  standards  established by
the  American  Institute of Certified  Public  Accountants.  A review of interim
financial  information consists principally of applying analytical procedures to
financial  data and making  inquiries of persons  responsible  for financial and
accounting matters. It is substantially less in scope than an audit conducted in
accordance with generally accepted auditing standards, the objective of which is
the  expression  of an opinion  regarding the  financial  statements  taken as a
whole. Accordingly we do not express such an opinion.

          Based on our review,  we are not aware of any  material  modifications
that should be made to the accompanying  consolidated  financial  statements for
them to be in conformity with generally accepted accounting principles.

          The accompanying  consolidated financial statements have been prepared
assuming  Xechem  International,  Inc. and its  subsidiaries  will continue as a
going concern. As discussed in Note 2 to the consolidated  financial  statements
appearing in Form 10-KSB for the year ended  December  31,1999,  the Company has
suffered  recurring losses from operations and has a net capital deficiency that
raise  substantial  doubt  about its  ability to  continue  as a going  concern.
Management's  plans in regard to these matters are also described in Note 2. The
consolidated  financial  statements  do not include any  adjustments  that might
result from the outcome of this uncertainty.

                                        /s/  Wiss & Company
                                        ----------------------------------
                                        Wiss & Company, LLP

Livingston, New Jersey
August 04, 2000



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