HEMASURE INC
DEF 14A, 1998-04-30
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
Previous: PREISS BYRON MULTIMEDIA CO INC, 10KSB/A, 1998-04-30
Next: XCELLENET INC /GA/, 8-A12G/A, 1998-04-30



                                  SCHEDULE 14A

                            SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Filed by the Registrant [X]
Filed by a Party other than the Registrant [ ]
Check the appropriate box:
[ ] Preliminary Proxy Statement
[ ] Confidential, for Use of the Commission Only (as permitted by
    Rule 14a-6(e)(2))
[X] Definitive Proxy Statement
[ ] Definitive Additional Materials
[ ] Soliciting Material Pursuant to ss.240.14a-11(c) or ss.240.14a-12

                                  HemaSure Inc.
- --------------------------------------------------------------------------------

                (Name of Registrant as Specified In Its Charter)

- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

[X]  No fee required.
[ ] Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

     1) Title of each class of securities to which transaction applies:

        ------------------------------------------------------------------------

     2) Aggregate number of securities to which transaction applies:

        ------------------------------------------------------------------------

     3) Per unit price or other underlying value of transaction computed
        pursuant to Exchange Act Rule 0-11 (Set forth the amount on which the
        filing fee is calculated and state how it was determined):

        ------------------------------------------------------------------------

     4) Proposed maximum aggregate value of transaction:

        ------------------------------------------------------------------------

     5) Total fee paid:

        ------------------------------------------------------------------------

[  ] Fee paid previously with preliminary materials.

[  ] Check box if any part of the fee is offset as provided by Exchange Act
     Rule 0-11(a)(2) and identify the filing for which the offsetting fee was
     paid previously. Identify the previous filing by registration statement
     number, or the Form or Schedule and the date of its filing.

     1)  Amount Previously Paid:

         -----------------------------------------------------------------------

     2)  Form, Schedule or Registration Statement No.:

         -----------------------------------------------------------------------

     3)  Filing Party:

         -----------------------------------------------------------------------

     4)  Date Filed:

         -----------------------------------------------------------------------




<PAGE>



                                  HEMASURE INC.
                                 140 Locke Drive
                        Marlborough, Massachusetts 01752

                  NOTICE OF 1998 ANNUAL MEETING OF STOCKHOLDERS

                           To Be Held on May 26, 1998

     The 1998 Annual Meeting of  Stockholders  of HemaSure Inc. (the  "Company")
will be held at the Holiday Inn,  Boxborough  Woods,  Boxborough,  Massachusetts
01719, on Tuesday,  May 26, 1998 at 10:00 a.m.,  local time, to consider and act
upon the following matters:

     1.   To elect five  directors  to serve  until the next  Annual  Meeting of
          Stockholders.

     2.   To approve and adopt an amendment to the Company's 1995 Employee Stock
          Purchase  Plan to increase the number of  authorized  shares of common
          stock issuable thereunder from 100,000 to 250,000.

     3.   To approve and adopt certain  amendments  to the Company's  1994 Stock
          Option Plan.

     4.   To  transact  such other  business  as may  properly  come  before the
          meeting or any adjournment thereof.

     Stockholders  of  record  at the close of  business  on April 24,  1998 are
entitled to notice of, and to vote at, the meeting.  The stock transfer books of
the Company will remain open for the purchase and sale of the  Company's  common
stock, par value $.01 per share.

     All stockholders are cordially invited to attend the meeting.

                                             By Order of the Board of Directors



                                             JAMES B. MURPHY, Secretary

Marlborough, Massachusetts
April 30, 1998


     WHETHER OR NOT YOU EXPECT TO ATTEND THE MEETING,  PLEASE COMPLETE, DATE AND
SIGN THE ENCLOSED  PROXY CARD AND PROMPTLY  MAIL IT IN THE ENCLOSED  ENVELOPE IN
ORDER TO ASSURE REPRESENTATION OF YOUR SHARES AT THE MEETING. NO POSTAGE NEED BE
AFFIXED IF THE PROXY CARD IS MAILED IN THE UNITED STATES.



<PAGE>



                                  HEMASURE INC.
                                 140 Locke Drive
                        Marlborough, Massachusetts 01752

           Proxy Statement for the 1998 Annual Meeting of Stockholders

                           To Be Held on May 26, 1998

     This Proxy  Statement is furnished in connection  with the  solicitation of
proxies by the Board of Directors of HemaSure  Inc. (the  "Company")  for use at
the 1998 Annual  Meeting of  Stockholders  to be held on May 26, 1998 and at any
adjournment or adjournments of that meeting (the "Annual Meeting").  All proxies
will be voted in accordance with the instructions  contained therein,  and if no
choice is specified, the proxies will be voted in favor of the matters set forth
in the accompanying Notice of Meeting. Any proxy may be revoked by a stockholder
at any time before it is  exercised  by delivery  of written  revocation  to the
Secretary of the Company.

     The Company's  Annual Report for the year ended December 31, 1997, is being
mailed to  stockholders  with the  mailing of this  Notice of Meeting  and Proxy
Statement on or about April 30, 1998.

Voting Securities and Votes Required

     On April 24, 1998, the record date for the  determination  of  stockholders
entitled to notice of and to vote at the  meeting,  there were  outstanding  and
entitled  to vote an  aggregate  of  8,991,042  shares  of  common  stock of the
Company,  par value $.01 per share ("Common Stock").  Each share of Common Stock
is entitled to one vote.

     Under the  Company's  Bylaws,  the  holders of a majority  of the shares of
Common  Stock  issued,  outstanding  and  entitled  to vote on any matter  shall
constitute  a  quorum  with  respect  to  that  matter  at the  Annual  Meeting.
Stockholders  holding  shares  of  Common  Stock  who are  present  in person or
represented  by proxy  (including  stockholders  who abstain  from voting  their
shares or who do not vote with  respect to one or more of the matters  presented
for stockholder  approval) will be counted for purposes of determining whether a
quorum is present.

     The  affirmative  vote of the holders of a  plurality  of votes cast by the
stockholders entitled to vote at the Annual Meeting is required for the election
of directors. The affirmative vote of the holders of a majority of the shares of
Common  Stock  voting on the matter is required  for the approval of each of the
other matters to be voted upon.

     Stockholders who abstain from voting as to a particular  matter, and shares
held in "street  name" by brokers or nominees who indicate on their proxies that
they do not have discretionary  authority to vote such shares as to a particular
matter,  will not be counted as votes in favor of such matter, and will also not
be  counted  as  votes  cast  or  shares  voting  on such  matter.  Accordingly,
abstentions and "broker non-votes" will have no effect on the voting on a matter
that requires the affirmative vote of a certain  percentage of the votes cast or
shares voting on a matter.



                                       -1-

<PAGE>



Stock Ownership of Certain Beneficial Owners and Management

     The following table sets forth certain information, as of January 31, 1998,
with  respect  to any person  (including  any  "group,"  as that term is used in
Section  13(d)(3)  of the  Securities  Exchange  Act of 1934,  as  amended  (the
"Exchange  Act")) who is known to the Company to be the beneficial owner of more
than five percent of any class of the  Company's  voting  securities,  and as to
those shares of the Company's equity  securities  beneficially  owned by each of
its directors and nominees for director,  the executive  officers of the Company
named in the  Summary  Compensation  Table under the  heading  "Compensation  of
Executive  Officers" below, and all of its directors and executive officers as a
group.  Unless otherwise  specified in the table below, such information,  other
than information  with respect to the directors and officers of the Company,  is
based on a review of statements  filed, or that should have been filed, with the
Securities and Exchange  Commission pursuant to Sections 13(d), 13(f), and 13(g)
of the Exchange Act with respect to the Company's  Common  Stock.  As of January
31, 1998, there were 8,991,042 shares of Common Stock outstanding.

     The number of shares of Common Stock beneficially owned by each director or
executive  officer  is  determined  under the rules of the  Commission,  and the
information is not necessarily  indicative of beneficial ownership for any other
purpose. Under such rules,  beneficial ownership includes any shares as to which
the individual has sole or shared voting power or investment  power and also any
shares  which the  individual  has the  right to  acquire  within 60 days  after
January 31, 1998 through the exercise of any stock option or other right. Unless
otherwise indicated, each person has sole investment and voting power (or shares
such power with his or her spouse)  with  respect to the shares set forth in the
following table. The inclusion  herein of any shares deemed  beneficially  owned
does not constitute an admission of beneficial ownership of those shares. Unless
otherwise specified, the address for each person below is c/o HemaSure Inc., 140
Locke Drive, Marlborough, Massachusetts 01752.
<TABLE>
<CAPTION>


                                                                           Shares of               Percentage of
                                                                          Common Stock                 Common
                                                                          Beneficially                 Stock
                         Name and Address                                    Owned                  Outstanding
                         ----------------                                 ------------             -------------
<S>                                                                       <C>                      <C>

Sepracor Inc.......................................................          3,000,000                33.1%
         111 Locke Drive
         Marlborough, MA 01752
Novo Nordisk A/S(1)................................................            827,375                 9.1%
         405 Lexington Avenue
         Suite 6400
         New York, NY 10017-6401
Nicholas Madonia, Trustee(2).......................................            489,000                 5.4%
         Madonia, Pilles & Co., P.A.
         30 Outwater Lane
         Garfield, NJ  07026
Timothy J. Barberich(3)............................................             61,875                 *
John F. McGuire....................................................             20,000                 *
David S. Barlow(4).................................................             15,375                 *



                                       -2-

<PAGE>



                                                                           Shares of               Percentage of
                                                                          Common Stock                 Common
                                                                          Beneficially                 Stock
                         Name and Address                                    Owned                  Outstanding
                         ----------------                                 ------------             -------------

Rolf S. Stutz(4)...................................................          18,375                    *
Justin E. Doheny...................................................               0                    *
Peter C. Sutcliffe.................................................           1,881                    *
James B. Murphy....................................................               0                    *
All directors and executive officers as a group                             117,506                    1.3%
(persons)(5).......................................................
</TABLE>

- ---------------
*    Represents holdings of less than one percent.

(1)  On  January  6,  1988,  the  Company  converted  all  indebtedness  under a
     convertible  subordinated  promissory  note  issued  to Novo  Nordisk  A/S,
     pursuant to the terms thereof,  into shares of Common Stock at a conversion
     price of $10.50 per share. Novo Nordisk A/S has contested the conversion of
     the note, including the forgiveness of $3 million of indebtedness  pursuant
     to the terms thereof.

(2)  Mr.  Madonia  is  the  trustee  for  three  trusts  (the  "Trusts")   which
     collectively  hold 489,000 shares of Common Stock.  In accordance  with the
     terms of the Trusts' governing documents, Mr. Madonia has the sole power to
     vote and sole power to  dispose  of the shares of Common  Stock held by the
     trustee.  Each of the Trusts is a charitable  remainder trust in accordance
     with the applicable  rules and regulations of the Internal  Revenue Code of
     1986, as amended.

(3)  Includes 49,875 shares of Common Stock which Mr. Barberich has the right to
     acquire  within 60 days after January 31, 1998 upon exercise of outstanding
     stock options.

(4)  Includes  12,375  shares of Common  Stock which each of Messrs.  Barlow and
     Stutz has the right to acquire  within 60 days after  January 31, 1998 upon
     exercise of outstanding stock options.

(5)  Includes an aggregate of 74,625  shares of Common Stock which all executive
     officers  and  directors  have the right to  acquire  within 60 days  after
     January 31, 1998 upon exercise of outstanding stock options.


                              ELECTION OF DIRECTORS

     The persons named in the enclosed proxy will vote to elect as directors the
five  nominees  named  below,  unless  the  proxy  is  marked  otherwise.  If  a
stockholder returns a proxy without contrary instructions,  the persons named as
proxies will vote to elect as directors the nominees  named below,  each of whom
is currently a member of the Board of Directors of the Company.

     Each director will be elected to hold office until the 1999 Annual  Meeting
of  Stockholders  and until his successor is duly elected and qualified.  All of
the nominees have indicated their willingness to serve, if elected;  however, if
any nominee should be unable to serve, the shares of Common Stock represented by
proxies  may be  voted  for a  substitute  nominee  designated  by the  Board of
Directors.



                                       -3-

<PAGE>



     There  are no  family  relationships  between  or  among  any  officers  or
directors of the Company.

     Set forth  below are the name and age of each member of, or nominee to, the
Board of  Directors,  and the  positions  and offices held by him, his principal
occupation  and  business  experience  during the past five years,  the names of
other  publicly held  companies of which he serves as a director and the year of
the  commencement  of his term as a director of the  Company.  Information  with
respect  to the  number of shares of  Common  Stock  beneficially  owned by each
director,  directly or indirectly,  as of January 31, 1998,  appears above under
the heading "Stock Ownership of Certain Beneficial Owners and Management."

     John T.  Kimbell,  served as a director of the Company  from  January  1994
until his death in September  1997. The Board of Directors and management of the
Company regret the loss of Mr. Kimbell and are deeply grateful for his dedicated
service as a member of the Board of Directors and for his lifelong contributions
to making blood safer.

     In April 1997, Messrs. Philip M. Hampton, Steven H. Rouhandeh and Eugene J.
Zurlo resigned as directors of the Company.

                              Nominees For Director

     Timothy J.  Barberich,  age 50, has served as  Chairman of the Board of the
Company since April 1997, as a director since the Company's organization in 1993
and was  Chairman of the Board of  Directors  from 1993 until  March  1996.  Mr.
Barberich   was  a  founder  of   Sepracor   Inc.   ("Sepracor"),   a  specialty
pharmaceutical company, and has served as President, Chief Executive Officer and
a director  of Sepracor  since  1984.  As of January  31,  1998,  Sepracor  owns
approximately 33% of the outstanding Common Stock of the Company.  Mr. Barberich
also serves as Chairman of the board of directors  of BioSepra  Inc., a publicly
traded subsidiary of Sepracor engaged in the manufacture of instrumentation  and
media for the pharmaceutical industry.

     David S.  Barlow,  age 41, has served as a director  of the  Company  since
January  1994.  Mr. Barlow has been  Executive  Vice  President  and  President,
Pharmaceuticals  Division  of Sepracor  since  October  1995.  From July 1993 to
October 1995,  Mr. Barlow held the position of Senior Vice President and General
Manager of the Pharmaceuticals  Division of Sepracor.  From 1991 to 1993, he was
president of the Business Group, a management  consulting firm.  Previously,  he
was Vice  President,  Worldwide  Marketing  and Business  Development  of Armour
Pharmaceutical  Company, a subsidiary of Rhone-Poulenc Rorer, from 1988 to 1991.
Prior to that time, he was associated with Pfizer Inc. and Ares-Serono,  Inc. in
various business planning and marketing positions.

     Rolf S.  Stutz,  age 48,  has  served as a director  of the  Company  since
January 1994.  Mr. Stutz has been Chairman  (since June 1996),  Chief  Executive
Officer  (since 1983) and a director of Zoll  Medical  Corporation  ("Zoll"),  a
manufacturer of  cardiovascular  monitoring and treatment  equipment.  He served
previously as President of Zoll from 1983 to June 1996.  From 1979 to 1983,  Mr.
Stutz held a variety of domestic and  international  management  positions  with
Millipore Corporation, an industrial filtration manufacturer.  Mr. Stutz is also
a director of Cambridge  Heart,  Inc., a  corporation  engaged in the  research,
development,  and  commercialization  of products for non-invasive  diagnosis of
cardiac disease.

     John F.  McGuire,  age 51,  has  served as Chief  Executive  Officer  and a
director of the Company since April 1997. Prior to that time, Mr. McGuire served
as Vice  President  and  General  Manager of Johnson & Johnson's  ("J&J")  Ortho
Diagnostic Systems Blood Bank Business Unit since January 1996.


                                       -4-

<PAGE>



From  March  1995 to  January  1996,  Mr.  McGuire  held  the  position  of Vice
President,  Sales & Marketing,  North America for J&J. From August 1990 to March
1995, Mr. McGuire served as Managing Director of Ortho Diagnostic Systems,  U.K.
and Belgium for J&J. From  September  1988 to August 1990,  Mr. McGuire held the
position of Marketing  Director for the AIDS and Hepatitis Business Unit of J&J.
From 1977 to 1988, Mr. McGuire held various management  positions at E.I. DuPont
De Nemours &  Company,  the last of which was  National  Sales  Manager,  AIDS &
Hepatitis  Business.  Mr.  McGuire is a member of the Board of  Trustees  of the
National Blood Foundation Trust Fund and of the Bergen Community Blood Center.

     Justin E.  Doheny,  age 46, has been  Executive  Vice  President  and Chief
Operating  Officer of Saint Peter's  Medical  Center,  New Brunswick,  NJ, since
August  1997.  During  1996  (June-October),  Mr.  Doheny  served as Senior Vice
President of Saint Barnabas Health Care System in Livingston,  NJ. From December
1985 until June 1996, Mr. Doheny held the position of President of Wayne General
Hospital,  located  in Wayne,  NJ.  Mr.  Doheny is also  Chairman  of the Bergen
Community Regional Blood Center.

Board and Committee Meetings

     The Company has a standing Audit Committee of the Board of Directors, which
provides the opportunity  for direct contact  between the Company's  independent
accountants and the Board of Directors.  The Audit Committee has  responsibility
for  recommending  the  appointment  of the Company's  independent  accountants,
reviewing the scope and results of audits and  reviewing the Company's  internal
accounting control policies and procedures.  The Audit Committee did not meet in
1997.  In 1997,  the  members of the Audit  Committee  were Mr.  Kimbell and Mr.
Hampton  until April 1997,  Mr.  Kimbell from April 1997 until August 1997,  Mr.
Kimbell and Mr. Stutz from August 1997 until  September  1997, and Mr. Stutz for
the remainder of 1997.

     The  Company  also has a standing  Compensation  Committee  of the Board of
Directors,  which provides  recommendations to the Board of Directors  regarding
compensation programs of the Company. The Compensation  Committee is responsible
for establishing and modifying the compensation of all corporate officers of the
Company,  adoption and amendment of all stock option and other employee  benefit
plans,   and  the  engagement  of,  terms  of  any  employment   agreements  and
arrangements  with, and termination  of, all corporate  officers of the Company.
The Compensation Committee did not meet during 1997. In 1997, the members of the
Compensation  Committee were Messrs. Kimbell and Stutz until September 1997, and
Mr.  Stutz  from  September  1997  until  December  1997.  See  "Report  of  the
Compensation Committee" below.

     The Company does not have a nominating  committee or a committee  serving a
similar  function.  Nominations  are  made by and  through  the  full  Board  of
Directors.

     The Board of Directors  held seven  meetings  during 1997.  Each  director,
other  than  Messrs.  Hampton,  Rouhandeh  and  Zurlo who are  addressed  below,
attended  at least 75% of the total  number of meetings  (including  consents in
lieu of meetings) of the Board of  Directors.  Messrs.  Hampton,  Rouhandeh  and
Zurlo attended at least 75% of the total number of meetings  (including consents
in lieu of  meetings)  of the Board of  Directors  which took  place  during the
period of their respective directorships.



                                       -5-

<PAGE>



Compensation for Directors

     Directors  who are neither  officers nor employees of the Company or of any
subsidiary  of the Company (the  "Outside  Directors")  receive  $1,000 for each
meeting  of the  Board  they  attend  and are  entitled  to  participate  in the
Company's  1994  Director  Stock Option Plan, as amended (the  "Director  Option
Plan"),  provided that Mr. Barberich and Mr. Barlow do not receive  compensation
for attendance at meetings of the Board. Directors who are officers or employees
of the Company do not receive any additional  compensation for their services as
directors. On January 5, 1994, options to purchase an aggregate of 75,000 shares
of Common Stock at an exercise  price of $2.00 per share were granted  under the
Director Option Plan to the following directors:  Mr. Barberich,  45,000 shares,
and Mr. Barlow,  Mr. Kimbell and Mr. Stutz,  7,500 shares each. On May 17, 1995,
options to purchase  1,500 shares of Common Stock at an exercise  price of $5.50
per  share  were  granted  under  the  Director  Option  Plan  to the  following
directors: Mr. Barberich, Mr. Barlow, Mr. Kimbell and Mr. Stutz. On February 15,
1996,  options to purchase 18,750 shares of Common Stock at an exercise price of
$12.375  per  share  were  granted  under  the  1994  Stock  Option  Plan to Mr.
Barberich. On May 16, 1996, options to purchase an aggregate of 39,000 shares of
Common  Stock at an exercise  price of $16.25 per share were  granted  under the
Director Option Plan to the following directors:  Mr. Barberich, Mr. Barlow, Mr.
Kimbell,  and Mr. Stutz, 9,750 shares each. On May 15, 1997, options to purchase
an aggregate of 12,000 shares of Common Stock at an exercise  price of $1.75 per
share were granted under the Director  Option Plan to the  following  directors:
Mr. Barberich, Mr. Barlow, Mr. Kimbell and Mr. Stutz, 3,000 shares each.

                      EXECUTIVE OFFICERS OF THE REGISTRANT

     The following table sets forth the names, ages and positions of the current
executive officers of the Company.
<TABLE>
<CAPTION>

                  Name                        Age                  Position
                  ----                        ---                  --------
<S>                                          <C>          <C>

John F. McGuire.............................    51        President, Chief Executive Officer and Director

James B. Murphy.............................    41        Senior Vice President, Finance and Administration

 Peter Sutcliffe  ..........................    48        Vice President and Chief Operating Officer
</TABLE>


     Mr.  McGuire's  biography  is set forth under  "Election  of  Directors  --
Nominees for Director."

     Mr. Murphy has served as Senior Vice President,  Finance and Administration
since  February  1996.  From  April  1994 to  January  1996,  he  served as Vice
President and Corporate  Controller of the Company.  Prior to that, from 1990 to
April 1994,  he served as  Corporate  Controller  of Sepracor.  Previously,  Mr.
Murphy held the positions of Senior Corporate  Accountant at BBN Inc. and Senior
Accountant at Arthur Andersen LLP.

     Mr.  Sutcliffe has served as Chief  Operating  Officer of the Company since
April 3,  1998.  From May 1996 until that  time,  Mr.  Sutcliffe  served as Vice
President of  Manufacturing  Operations of the Company.  From May 1982 until May
1996, Mr. Sutcliffe held the position of Vice President Manufacturing for Cornig
Costar Incorporated.  From 1976 until 1982, he was a plant manufacturing manager
at Millipore Corporation.


                                       -6-

<PAGE>



Compensation of Executive Officers

     Summary   Compensation  Table.  The  following  table  sets  forth  certain
information  with respect to the annual and long-term  compensation for the last
three fiscal years of the Company's  President and Chief  Executive  Officer and
the Company's other executive  officers  (including  former executive  officers)
whose total annual  salary and bonus for 1997 exceeded  $100,000  (collectively,
the "Named Executive Officers").



                           SUMMARY COMPENSATION TABLE
<TABLE>
<CAPTION>

                                                                                            Long-Term
                                                                                          Compensation
                                                   Annual Compensation                       Awards
                                 ------------------------------------------------------   ------------
                                                                                           Securities             All
                                                                         Other Annual      Underlying             Other
                                                                         Compensation     Options/SARs        Compensation
   Name and Principal Position   Year        Salary ($)    Bonus($)         ($)(1)                               ($)(2)
   ---------------------------   ----        ----------    --------        --------     --------------     ------------
<S>                              <C>         <C>          <C>              <C>          <C>                <C>

John F. McGuire................. 1997          $140,302    $75,000             -           600,000                $708
    President and                1996                 -          -             -                 -                   -
    Chief Executive Officer      1995                 -          -             -                 -                   -
James B. Murphy................. 1997          $119,387                                     60,000                $222
    Senior Vice President        1996           112,926          0             0            30,000                 247
    Finance and Administration   1995            93,013     20,000             0            12,000                 203
Steven H. Rouhandeh (3)......... 1997          $239,064                                                           $260
    President and                1996           194,157          0             0           480,000                 266
    Chief Executive Officer      1995           144,629     50,000             0           150,000                 198
Jeffrey B. Davis (3)............ 1997          $234,282                                                           $435
    Senior Vice President        1996           116,713          0             0           150,000                 255
    Chief Financial Officer      1995                 -          -             -                 -                   -
Edward W. Kelly (3)............. 1997          $188,342                                                         $3,616
    Senior Vice President        1996           106,057          -             0            45,000               2,036
    Chief Operating Officer      1995                 -          -             -                 -                   -

</TABLE>
- -------------

(1)  Other  compensation in the form of perquisites and other personal  benefits
     has  been  omitted  if  such   perquisites  and  other  personal   benefits
     constituted  less than the lesser of $50,000 or 10% of the total salary and
     bonus for the Named Executive Officer.
(2)  Represents the taxable portion of group life insurance paid by the Company.
(3)  Effective April 2, 1997, Messrs. Rouhandeh,  Davis, and Kelly were relieved
     of their duties as executive officers and employees of the Company, and, in
     connection  therewith,  all  unvested  options  previously  granted to such
     persons, aggregating 480,000, 150,000, and 45,000, respectively, expired by
     their terms.




                                       -7-

<PAGE>



         Option Grant Table. The following table sets forth certain information
regarding options granted during the year ended December 31, 1997 by the Company
to the Named Executive Officers.



                         OPTION/SAR GRANTS IN LAST YEAR
<TABLE>
<CAPTION>

                              Individual Grants
                          --------------------------
                                        Percent of                   Market
                                           Total                    Price of
                           Number of      Options/                  Securities
                          Securities       SARs       Exercise     Underlying                Potential Realizable Value
                          Underlying     Granted to       or         Options/                 at Assumed Annual Rates of
                         Options/SARS  Employees In     Base          SARs                    Stock Price Appreciation
                            Granted       Fiscal        Price       On Grant    Expiration       For Option Term(2)
                                                                                            ------------------------
      Name                  (#)(1)         Year        ($/sh)         Date         Date          5%($)        10%($)
- -----------------------  ------------  ------------   --------    ------------- ----------  ------------   ---------
<S>                      <C>           <C>            <C>         <C>           <C>         <C>

John F. McGuire             156,064       12.4861     $2.563        $2.563       4/02/07     $251,522.84  $  637,489.29
                            443,936       35.5177      2.563         2.563       4/02/07      715,561.32   1,813,372.87

James B. Murphy..........    60,000        4.8003     $3.500         $3.50       4/16/07     $131,976.43    $334,401.53
                             12,000        0.9600      3.500          3.50       4/16/07       26,413.57      66,937.18
                             30,000        2.4001      3.500          3.50       4/16/07       66,033.94     167,342.96
</TABLE>





- ---------------

(1)  Options vest in up to five equal annual installments beginning on the first
     anniversary of the date of grant.

(2)  Amounts represent  hypothetical gains that could be achieved for options if
     exercised and sold at the end of the option term.  These gains are based on
     assumed rates of stock price appreciation of 5% and 10% compounded annually
     from the date options are granted.  Actual  gains,  if any, on stock option
     exercises will depend on the future  performance of the Common Stock on the
     date on which the options are sold.






                                       -8-

<PAGE>



     Year-End Option Table.  The following table sets forth certain  information
regarding options held as of December 31, 1997 by the Named Executive  Officers.
No Named Executive Officer exercised stock options in 1997.

                AGGREGATED OPTION/SAR EXERCISES IN LAST YEAR AND
                           YEAR-END OPTION/SAR VALUES
<TABLE>
<CAPTION>


                                                                           Number of
                                                                          Securities
                                                                          Underlying           Value of Unexercised
                                                                          Unexercised              In-The-Money
                                                                        Options/SARs at           Options/SARs at
                                                                      Fiscal Year-End (#)     Fiscal Year-End ($)(1)
                                                                      -------------------     ----------------------
                                         Shares
                                        Acquired
                                           on             Value          Exercisable/              Exercisable/
                Name                  Exercise (#)    Realized ($)     Unexercisable(2)            Unexercisable
- ------------------------------------  ------------    ------------     ----------------       ----------------------
<S>                                   <C>             <C>              <C>                         <C>

John F. McGuire.....................                                       0/600,000                   0/0

James B. Murphy.....................                                    19,200/100,800                 0/0

Steven H. Rouhandeh(2)..............                                       150,000/0                   0/0

Jeffrey B. Davis(2).................                                          0/0                      0/0

Edward W. Kelly(2)..................                                          0/0                      0/0
</TABLE>

- ---------------

(1)  Value is based on the closing sales price of the Company's  Common Stock on
     December  31, 1997  ($0.938),  the last trading day of the  Company's  1997
     fiscal year, less the applicable option exercise price.

(2)  Effective April 2, 1997, Messrs.  Rouhandeh,  Davis and Kelly were relieved
     of their duties as executive  officers of the Company,  and, in  connection
     therewith,  all  unvested  options  previously  granted  to  such  persons,
     aggregating 675,000, expired by their terms.

     Option  Repricing  Table.  The  table  set  forth  below  provides  certain
information  concerning all  adjustments  to the exercise  prices of outstanding
stock  options  held by  executive  officers of the  Company  during the past 10
years.

                         TEN-YEAR OPTION/SAR REPRICINGS
<TABLE>
<CAPTION>

                                            Number of
                                           Securities     Market Price      Exercise                    Length of Original
                                           Underlying      of Stock at      Price at                        Option Term
                                          Options/SARs       Time of        Time of                      Remaining at Date
                                           Repriced or    Repricing or    Repricing or       New          of Repricing or
           Name                 Date         Amended        Amendment      Amendment    Exercise Price   Amendment (years)
                                ----         -------        ---------      ---------    --------------   -----------------
<S>                           <C>            <C>            <C>            <C>          <C>              <C>

James B. Murphy...........    4/16/97         12,000           $3.50        $  7.50          $3.50           9
                                              30,000           $3.50         $12.38          $3.50           9

Hans J. Heiniger..........    4/16/97         25,000           $3.50        $  7.50          $3.50           9
                              4/16/97         35,000           $3.50         $12.38          $3.50           9
                              3/16/95         10,000           $3.38        $  7.52          $3.38           9

John E. McCray............    4/16/97         19,600           $3.50         $ 7.50          $3.50           9
                              4/16/97         15,000           $3.50         $12.38          $3.50           9

Eugene Zurlo..............    3/16/95        120,000           $3.38        $  8.50          $3.38          10
</TABLE>



                                       -9-

<PAGE>



Report of the Compensation Committee

     The  Compensation  Committee of the Board of Directors,  which is currently
comprised  of one  non-employee  director,  Rolf S. Stutz,  is  responsible  for
determining the compensation  package of each executive officer and recommending
it to the Board of Directors.  The Compensation  Committee sets the compensation
for executive officers and establishes  compensation  policies for the Company's
Chief  Executive  Officer and the other executive  officers of the Company.  All
decisions by the Compensation Committee are reviewed by the Board of Directors.

     The  Company's  executive  compensation  program is designed to promote the
achievement of the Company's business goals, and, thereby, to maximize corporate
performance  and  stockholder  returns.  Executive  compensation  consists  of a
combination  of  base  salary  and  stock-based  incentives.   The  Compensation
Committee   considers  stock  incentives  to  be  a  critical  component  of  an
executive's compensation package in order to help align executive interests with
stockholder interests.

     Compensation Philosophy

     The  objectives  of  the  executive   compensation  program  are  to  align
compensation with business objectives and individual performance,  and to enable
the Company to attract, retain and reward executive officers who are expected to
contribute to the  long-term  success of the Company.  The  Company's  executive
compensation  philosophy  is based on the  principles  of  competitive  and fair
compensation and sustained performance.

  o  Competitive and Fair Compensation

     The Company is committed to  providing  an executive  compensation  program
     that helps attract and retain highly qualified  executives.  To ensure that
     compensation  is  competitive,   the  Company   compares  its  compensation
     practices  with  those  of other  companies  in the  industry  and sets its
     compensation   guidelines  based  on  this  review.  The  Company  believes
     compensation for its executive officers is within the range of compensation
     paid  to  executives   with  comparable   qualifications,   experience  and
     responsibilities  in the same or similar  businesses and of comparable size
     and success.  The Company also strives to achieve  equitable  relationships
     both  among  the  compensation  of  individual  officers  and  between  the
     compensation of officers and other employees throughout the organization.

  o  Sustained Performance

     Executive  officers  are  rewarded  based upon  corporate  performance  and
     individual performance. Corporate performance is evaluated by reviewing the
     extent to which  strategic and business plan goals are met,  including such
     factors  as  achievement  of  operating  budgets,  timely  development  and
     commercial  introduction  of new processes and products,  establishment  of
     strategic  licensing  and  development  alliances  with third  parties  and
     performance relative to competitors. Individual performance is evaluated by
     reviewing attainment of specified  individual  objectives and the degree to
     which teamwork and Company values are fostered.

     In evaluating each executive officer's  performance,  the Company generally
conforms to the following process:



                                      -10-

<PAGE>



     o    Company and individual  goals and  objectives  are  established at the
          beginning of the performance cycle.

     o    At  the  end of  the  performance  cycle,  the  accomplishment  of the
          executive's  goals and objectives and his contributions to the Company
          are evaluated.

     o    The  executive's  performance  is then  compared with peers within the
          Company and the results are communicated to the executive.

     o    The  comparative  results,   combined  with  comparative  compensation
          practices  of  other  companies  in the  industry,  are  then  used to
          determine salary and stock compensation levels.

     Annual compensation for the Company's  executives generally consists of two
elements:  salary  and stock  options.  From  time to time,  the  Committee  may
consider payment of cash bonuses based upon performance in a particular year.

     The salary for  executives is generally set by reviewing  compensation  for
competitive  positions in the market and the historical  compensation  levels of
the executives.  Increases in annual salaries are based on actual  corporate and
individual  performance  against  targeted  performance  and various  subjective
performance  criteria.  Targeted  performance  criteria vary for each  executive
based  on his  area  of  responsibility,  and  may  include  achievement  of the
operating  budget  for the  Company  as a whole  or of a  business  group of the
Company,  continued  innovation  in  development  and  commercialization  of the
Company's   technology   and  products,   timely   development   and  commercial
introduction  of  new  products  or  processes,   implementation   of  financing
strategies and  establishment of strategic  licensing and development  alliances
with third  parties.  Subjective  performance  criteria  include an  executive's
ability to motivate others,  develop the skills necessary to grow as the Company
matures,  recognize and pursue new business  opportunities and initiate programs
to enhance  the  Company's  growth and  success.  The  Committee  does not use a
specific  formula based on these targeted  performance and subjective  criteria,
but instead makes an evaluation of each  executive  officer's  contributions  in
light of all such criteria.

     Compensation  at the  executive  officer  level also includes the long-term
incentives  afforded by stock  options.  The stock option program is designed to
promote the identity of long-term  interests between the Company's employees and
its shareholders  and assist in the retention of executives.  The size of option
grants is  generally  intended  to reflect  the  executive's  position  with the
Company and his contributions to the Company, including his success in achieving
the  individual   performance  criteria  described  above.  The  option  program
generally  uses a vesting  period of up to five years to encourage key employees
to continue in the employ of the Company. All stock options granted to executive
officers in 1997 were granted at fair market value on the date of grant.  During
1997,  all  executive  officers  received  options to purchase an  aggregate  of
702,000 shares of Common Stock,  at a weighted  average  exercise price of $2.70
per share.

     Executive  officers are also eligible to  participate in the Company's 1995
Employee Stock Purchase  Plan, as amended (the  "Purchase  Plan").  The Purchase
Plan is  available  to  virtually  all  employees  of the Company and  generally
permits  participants  to  purchase  shares of  Common  Stock at a  discount  of
approximately  15% from the fair  market  value at the  beginning  or end of the
applicable purchase period.

     Base Salaries

     Base salaries paid to the Named  Executive  Officers in 1997 were set forth
in their respective  employment  agreements.  The employment agreements with the
Named Executive Officers are described


                                      -11-

<PAGE>



more fully  under  "Certain  Relationship  and Related  Transactions."  The base
salaries of executives without employment  agreements have been set by reviewing
compensation  for  competitive  positions  in  the  market  and  the  historical
compensation levels of such executives.

     Annual Bonus

     Other than John F.  McGuire  who  received a $75,000  bonus,  no  executive
officer received a bonus in respect of the Company's 1997 fiscal year due to the
failure to achieve certain  performance  related goals which were established by
the Board in 1997.

     Compliance with Internal Revenue Code Section 162(m)

     Section  162(m) of the  Internal  Revenue  Code of 1986,  as  amended  (the
"Code"),  enacted  in  1993,  generally  disallows  a tax  deduction  to  public
companies  for  compensation  over $1 million  paid to the  corporation's  Chief
Executive  Officer and four other most highly  compensated  executive  officers.
Qualifying  performance  compensation will not be subject to the deduction limit
if  certain  requirements  are met.  Subsequent  to the death of Mr.  Kimbell in
September 1997 (who was a member of the Compensation Committee), any performance
based  compensation  approved by the Board would not be "qualifying  performance
compensation" under Section 162(m) of the Code because it was not established by
a compensation committee comprised of two or more outside directors. The Company
intends to structure the  performance-based  portion of the  compensation of its
executive  officers  (which  currently  consists  of  stock  option  grants  and
performance  based  bonuses  described  above) in the  future  in a manner  that
complies with the new statute to mitigate any disallowance of deductions.

     Repricing of Options

THE  FOLLOWING  SECTION  OF THIS  PROXY  STATEMENT  SHALL  NOT BE  DEEMED  TO BE
INCORPORATED  BY REFERENCE INTO ANY FILING BY THE COMPANY WITH THE SEC UNDER THE
SECURITIES ACT OF 1933, AS AMENDED,  OR THE SECURITIES  EXCHANGE ACT OF 1934, AS
AMENDED,  NOTWITHSTANDING  ANY SUCH  INCORPORATION  BY  REFERENCE  OF ANY  OTHER
PORTIONS OF THIS PROXY STATEMENT.

     On April 16, 1997, the Compensation Committee authorized a program pursuant
to which the  Company  offered to holders  of certain  "out-of-the-money"  stock
options  issued under the  Company's  1994 Stock  Option  Plan,  as amended (the
"Plan"),  the right to surrender those options for  cancellation in exchange for
new options  exercisable at $3.50 per share,  which was the fair value per share
of Common Stock on April 16, 1997.  Each new option is exercisable  for the same
number  of  shares  as the  canceled  option  for  which it was  exchanged,  and
generally  follows the same type of vesting and  expiration  schedules,  but the
vesting and  expiration  schedules  begin on the new grant date.  The  Committee
believes that this exchange program was in the best interests of the Company and
was  necessary  in order for the Plan to  continue  serving  one of its  primary
purposes  -- to  encourage  key  employees  to remain  with the  Company  and to
contribute  toward efforts to increase the value of the Company's  Common Stock.
Prior  to  their   cancellation   pursuant   to  the   exchange   program,   the
out-of-the-money  options had exercise prices ranging from $7.50 to $12.38,  and
therefore provided little incentive to employees.

                                                     Compensation Committee

                                                     Rolf S. Stutz




                                      -12-

<PAGE>



Compensation Committee Interlocks and Insider Participation

     The current member of the  Compensation  Committee is Mr. Stutz.  Mr. Stutz
was not at any time  during  1997,  or  formerly,  an officer or employee of the
Company or any subsidiary of the Company, nor has any member of the Compensation
Committee had any relationship with the Company requiring  disclosure under Item
404 of Regulation S-K under the Exchange Act.

     No  executive  officer of the Company has served as a director or member of
the Compensation  Committee (or other committee serving an equivalent  function)
of any other entity,  one of whose executive officers served as a director of or
member of the Compensation Committee of the Company.

Comparative Stock Performance

     The  comparative  stock  performance  graph below  compares the  cumulative
stockholder  return on the Common Stock of the Company for the period from April
7, 1994  through  the year ended  December  31, 1997 with the  cumulative  total
return on (i) the CRSP Total  Return  Index for The  Nasdaq  Stock  Market  (the
"Nasdaq Composite Index"),  and (ii) the Nasdaq  Pharmaceutical  Index (assuming
the  investment  of $100 in the  Company's  Common Stock (at the initial  public
offering price), the Nasdaq Composite Index and the Nasdaq  Pharmaceutical Index
on April 7, 1994 and reinvestment of all dividends).

     Measurement  points  are on April 7, 1994 and the last  trading  day of the
years ended December 31, 1994, December 31, 1995, December 31, 1996 and December
31, 1997.  Prior to April 7, 1994, the Company's Common Stock was not registered
under the Exchange Act.

<TABLE>
<CAPTION>

                                PERFORMANCE GRAPH

                           4/7/94      12/31/94       12/31/95       12/31/96   12/31/97
<S>                          <C>         <C>            <C>            <C>      <C>
HemaSure Inc.                $100        $ 46           $182           $ 89     $ 13
Nasdaq Composite Index        100         103            145            179      220
Nasdaq Pharmaceutical Index   100          92            169            169      175
</TABLE>




                                      -13-

<PAGE>



Certain Relationships and Related Transactions

     Sepracor.  The Company was  organized in December  1993 as a subsidiary  of
Sepracor.  Effective January 1, 1994, Sepracor  transferred its blood filtration
and membrane  filter  design  business to the Company in exchange for  3,000,000
shares  of Common  Stock.  As of  January  31,  1998,  Sepracor  currently  owns
approximately 33% of the Company's  outstanding Common Stock. Messrs.  Barberich
and Barlow,  directors of the Company, are President and Chief Executive Officer
and  Executive   Vice  President  and   President,   Pharmaceuticals   Division,
respectively, of Sepracor.

     Employment Agreements.  Effective April 2, 1997, Messrs. Zurlo,  Rouhandeh,
Davis,  and Kelly  were  relieved  of their  duties as  executive  officers  and
employees of the  Company.  The Company  entered into a separation  agreement on
April 2,  1997  with  Mr.  Rouhandeh  (the  "Rouhandeh  Separation  Agreement"),
pursuant to which Mr.  Rouhandeh  will receive 52 weeks of severance  pay in the
aggregate amount of $245,000.  Pursuant to the terms of the Rouhandeh Separation
Agreement,  Mr. Rouhandeh agreed to cooperate with the Company in all litigation
or regulatory  matters arising out of or related to the business,  operations or
personnel of the Company from the date thereof until April 1, 1998. On August 1,
1997, the Company entered into a separation agreement with Mr. Davis (the "Davis
Separation  Agreement"),  pursuant to which Mr. Davis received $380,000 of total
severance  pursuant to the terms of his  employment  agreement in exchange for a
release of any and all claims he may have against the  Company.  Pursuant to the
terms of the Davis Separation Agreement,  Mr. Davis agreed to cooperate with the
Company in all litigation or regulatory matters arising out of or related to the
business,  operations  or personnel  of the Company from the date thereof  until
April 1, 1998. The Company entered into a master  consulting  agreement on April
2, 1997 with Mr. Zurlo (the "Consulting Agreement"), pursuant to which Mr. Zurlo
will provide confidential consulting services as an independent contractor.  The
initial  term of the  Consulting  Agreement  will  extend  through  March  2000.
Pursuant to the terms of the Consulting Agreement, Mr. Zurlo's compensation will
be negotiated on a project by project basis.

     The Company entered into an employment agreement,  as of April 1, 1997 (the
"Agreement"),  with John F. McGuire  which  provides  that Mr.  McGuire serve as
President and Chief Executive Officer of the Company. The Agreement provides for
a salary of $14,583  per month and an annual  bonus of $75,000 to be earned upon
the  achievement of certain goals as determined by the Board of Directors.  Upon
execution of the Agreement,  Mr. McGuire  received an option to purchase 600,000
shares of Common Stock at an exercise price equal to the "low" bid price for the
Common  Stock as quoted on the  Nasdaq  National  Market  System for the week of
April 4, 1997. The options vest in four equal annual installments  commencing in
1998.  Pursuant to the Agreement,  an additional 200,000 incentive stock options
were issued to Mr. McGuire in January,  1998. Finally,  pursuant to the terms of
the  Agreement,  if Mr.  McGuire is  terminated  other  than for cause,  he will
receive one year's  salary plus the bonus payable for the prior year, to be paid
monthly over the course of the 12 months following such termination, or until he
secures employment in an equivalent role.

     Novo Nordisk A/S. Under the terms of the May 1996 agreement relating to the
Company's  acquisition  of the  plasma  product  unit of Novo  Nordisk  A/S (the
"Denmark  Acquisition"),  the purchase  price to be paid for the plasma  product
unit was to be comprised of three portions:  (i) $1,800,000 was to be payable in
1998 in cash or common stock of the Company or a subsidiary  of the Company,  at
the Company's option; (ii) approximately $13,000,000 was to be payable from time
to time upon the sale of


                                      -14-

<PAGE>



acquired  inventory (valued at approximately  $13,000,000),  but in any event no
later than 1998,  provided that up to  approximately  $3,000,000 of such portion
could be forgiven in certain circumstances;  and (iii) approximately  $8,000,000
was to be payable in 1998 in cash or Common Stock of the Company or a subsidiary
of the Company, at the Company's option, provided that all of this portion would
be  forgiven in certain  circumstances.  In January  1997,  the Company and Novo
Nordisk  entered  into  a  Restructuring   Agreement  relating  to  the  Denmark
Acquisition  (the  "Restructuring  Agreement").  Pursuant  to the  Restructuring
Agreement,  approximately  $23,000,000 of indebtedness  owed to Novo Nordisk was
restructured  by way of  issuance  by  the  Company  to  Novo  Nordisk  of a 12%
convertible   subordinated   promissory   note  in  the   principal   amount  of
approximately $11,722,000,  which was due and payable on December 31, 20001 (the
"Note"),  with interest  payable  quarterly  (provided that up to  approximately
$3,000,000 would be forgiven in certain circumstances). Approximately $8,500,000
of the  reduction  of such  indebtedness  was  forgiven.  The  remainder  of the
reduction  represented a net amount due from Novo Nordisk to the Company related
to various service arrangements  between the two companies.  On January 6, 1998,
the Company elected to convert all indebtedness under the Note,  pursuant to the
terms thereof,  into shares of Common Stock of the Company at a conversion price
equal to $10.50 per share, or 827,375 shares.  Pursuant to a registration rights
agreement,  the Company  previously  granted Novo Nordisk  certain  registration
rights with respect to any shares of Common Stock  acquired by Novo Nordisk upon
conversion of the Note.  Novo Nordisk has contested the  conversion of the Note,
including the forgiveness of the $3,000,000  amount.  The Company  believes such
claims are without merit.




                                      -15-

<PAGE>



           APPROVAL OF AMENDMENTS TO 1995 EMPLOYEE STOCK PURCHASE PLAN

Summary of Amendment

     On April 3, 1998,  the  Company's  Board of Directors  adopted,  subject to
stockholder approval, an amendment to the Company's 1995 Employee Stock Purchase
Plan (as amended, the "Amended Purchase Plan") to provide for an increase,  from
100,000 to 250,000,  in the number of authorized shares of Common Stock issuable
under the Amended  Purchase Plan. The Board of Directors  believes that it is in
the best  interest of the Company to continue to  encourage  stock  ownership by
employees of the Company.

     The principal provisions of the Amended Purchase Plan are summarized below.
The following  summary of the material  provisions of the Amended  Purchase Plan
does not purport to be complete and is qualified in its entirety by the terms of
the Amended  Purchase Plan. A copy of the Amended  Purchase Plan may be obtained
from the Company by contacting  James B. Murphy,  Senior Vice President  Finance
and Administration, 140 Locke Drive, Malborough, Massachusetts 01752.

The Amended Purchase Plan

     The purpose of the Amended Purchase Plan is to provide  eligible  employees
of the Company and certain of its  subsidiaries  with  opportunities to purchase
shares of the Company's Common Stock.

     Administration.  The  Amended  Purchase  Plan will be  administered  by the
     --------------
Company's  Board  of  Directors  or by a  committee  appointed  by the  Board of
Directors (the "Committee"),  whose construction and interpretation of the terms
and provisions of the Amended Purchase Plan shall be final and conclusive.

     Eligibility.  With  certain  limited  exceptions  in the case of  employees
     -----------
already  holding a  significant  amount of Common  Stock,  each  employee of the
Company as of the date an offering  commences  and who  ordinarily  works twenty
(20) or more hours per week and more than five (5)  months per year is  eligible
to participate in the Amended Purchase Plan. As of April 30, 1998, approximately
45 employees were eligible to participate in the Amended Purchase Plan.

     Offerings.  The Company  will make one or more  offerings  to  employees to
     ---------
purchase stock under the Amended Purchase Plan. Offerings will begin each June 1
and December 1, or the first business day thereafter (the "Offering Commencement
Date"). The Offering  Commencement Date will begin a six (6) month period during
which payroll deductions will be made and held for the purchase of the Company's
common  stock at the end of the offering  period.  The Board of Directors of the
Committee  may,  at its  discretion,  select a  different  period of twelve (12)
months or less for  subsequent  offerings,  as further  detailed  in the Amended
Purchase Plan.

     Participation  and  Deductions.   An  employee  eligible  on  the  Offering
     ------------------------------
Commencement  Date may participate in an offering by completing and forwarding a
payroll  deduction  authorization  form at least  thirty  (30) days prior to the
applicable  Offering  Commencement  Date.  Payroll deductions may be made in one
(1%) percent increments from 1% to 10% of compensation (which excludes overtime,
incentive or bonus awards, allowances and reimbursements for expenses), with any
change in  compensation  during the  offering  period to result in an  automatic
corresponding change in the dollar amount withheld.  An employee may decrease or
discontinue his payroll  deduction once during the offering period,  by filing a
new payroll deduction authorization form. An employee may not, however, increase
his payroll deduction during the offering period. Unless an employee files a new
form or withdraws from the Amended


                                      -16-

<PAGE>



Purchase  Plan,  his deductions and purchases will continue at the same rate for
future offerings under the Amended Purchase Plan as long as the Amended Purchase
Plan remains in effect.

     No employee may be granted an option  which  permits his rights to purchase
the Company's  Common Stock under the Amended  Purchase Plan and any other stock
purchase  plan of the  Company and its  subsidiaries,  to accrue at a rate which
exceeds $25,000 of the fair market value of such Common Stock (determined at the
Offering  Commencement  Date of the offering  period) for each  calendar year in
which the option is outstanding at any time.

     Withdrawal  of Funds.  An  employee  may at any time  prior to the close of
     --------------------
business on the last  business  day in an offering  period,  and for any reason,
withdraw the funds  accumulated in the employee's  account and thereby  withdraw
from  participation  in the Amended Purchase Plan.  Partial  withdrawals are not
permitted.

     Purchase  of  Shares.  On the  Offering  Commencement  Date of an  offering
     --------------------
period,  the Company  will grant to each  participating  employee,  an option to
purchase,  on the last business day of such offering period, at the option price
provided for in the Amended  Purchase  Plan,  such number of whole shares of the
Company's Common Stock reserved for the purposes of the Amended Purchase Plan as
does not exceed the number of shares  determined by dividing six (6%) percent of
such employee's  annualized  compensation  for the  immediately  prior six-month
period by the price  determined in accordance  with the formula set forth in the
Amended Purchase Plan, but using the closing price on the Offering  Commencement
Date of such offering period.

     Each  employee who continues to be a  participant  in the Amended  Purchase
Plan at the end of the  offering  period shall be deemed to have  exercised  his
option at the applicable  option price on such date, and shall be deemed to have
purchased from the Company the applicable number of full shares of the Company's
Common Stock.  With minor  exceptions,  any balance  remaining in the employee's
payroll   deduction   account  at  the  end  of  the  offering  period  will  be
automatically refunded to the employee.




                                      -17-

<PAGE>



     Issuance of Certificates.  Certificates representing shares of Common Stock
purchased under the Amended  Purchase Plan may be issued only in the name of the
employee,  in the name of the employee and another  person of legal age as joint
tenants with rights of  survivorship,  or (in the Company's sole  discretion) in
the street name of a brokerage firm, bank or other nominee holder  designated by
the employee.

     Amendment and Termination. Subject to the approval of the stockholders in
certain circumstances, the Board of Directors may at any time, and from time to
time, amend the Amended Purchase Plan. The Amended Purchase Plan may be
terminated at any time by the Board of Directors. Upon termination of the
Amended Purchase Plan, all amounts in the accounts of participating employees
will be promptly refunded.

Federal Income Tax Consequences.

     The Amended  Purchase  Plan is intended  to qualify as an  "employee  stock
purchase  plan" as defined in Section 423 of the Code,  which  provides  that an
employee does not have to pay any federal  income tax when such  employee  joins
the Amended  Purchase  Plan,  or when an offering  period ends and such employee
receives  shares of the  Company's  Common  Stock.  The  employee  is,  however,
required  to pay a federal  income tax on the  difference,  if any,  between the
price at which he sells the shares and the price he or she paid for them.

     If an employee has owned shares for more than one year and disposes of them
at least two years after the date an offering period commenced, he will be taxed
as described  below. If the market price of the shares on the date they are sold
is less than the price paid for the shares under the Amended  Purchase Plan, the
employee  will incur a long term  capital  loss in the amount equal to the price
paid over the sale price.  If the sale price is higher than the price paid under
the Amended Purchase Plan, such employee will have to recognize  ordinary income
in an amount  equal to the lesser of the market  price of the shares on the date
the offering commenced over the price paid, or the excess of the sale price over
the price paid. Any further gain is treated as long-term capital gain. Except as
set forth below,  the Company will  generally not be entitled to a tax deduction
upon the  purchase or sale of shares  under the Amended  Purchase  Plan.  If the
employee sells the shares before he or she has owned them for more than one year
or  before  the  expiration  of a  two-year  period  commencing  on the date the
offering period commenced,  the employee will have to recognize  ordinary income
in the amount of the difference between the option price and the market price of
the  shares on the date of  purchase  and the  Company  will  receive an expense
deduction  for the same amount.  The employee  will  recognize a capital gain or
loss for the difference  between the sale price and the market price on the date
of purchase. The gain or loss will be long-term if the employee owned the shares
for more than one year.

Board Recommendation

     The Board of Directors  believes the Amended  Purchase  Plan is in the best
interests of the Company and its  stockholders  and therefore  recommends a vote
FOR this proposal.


                                      -18-

<PAGE>


              APPROVAL OF AMENDMENTS TO THE 1994 STOCK OPTION PLAN

Summary of the Amendments

     On April 3, 1998,  the  Company's  Board of Directors  adopted,  subject to
stockholder  approval,  an amendment and restatement of the Company's 1994 Stock
Option  Plan  (as  amended,  the  "Amended  Option  Plan")  to  (i)  incorporate
amendments  previously  adopted by the Board and  approved by the  stockholders,
(ii) make  certain  changes in light of  changes to Rule 16b under the  Exchange
Act, and (iii)  increase the number of shares  authorized for issuance under the
Amended Option Plan.

     The Board of Directors  adopted a so-called  "evergreen"  limitation on the
number of shares of Common  Stock that can be  transferred  with  respect to the
grant of options made under the Amended  Option Plan (i.e.,  the Amended  Option
Plan  expresses  the  maximum  number of shares  which may be  transferred  with
respect to the grant of options in terms of a percentage of outstanding  shares)
to ensure that the Company can continue to grant options to employees,  officers
and  directors  of,  and  consultants  or  advisors  to,  the  Company at levels
determined  appropriate by the Board of Directors.  This type of limitation will
replenish the shares  available under the Amended Option Plan,  without the need
for further amendment, in the event there is an increase in the number of shares
the Company has  outstanding.  The  amendment  provides  for a pool of shares of
Common Stock  reserved and available for issuance  under the Amended Option Plan
equal to the greater of (i)  2,500,000  shares of Common Stock and (ii) eighteen
(18%) percent of the issued and outstanding  shares,  calculated  generally with
respect  to the  number  of shares  outstanding  as of the last day of the prior
calendar year (assuming all unexpired and outstanding options are exercised).

     The principal  provisions of the Amended Option Plan are summarized  below.
The following summary of the material provisions of the Amended Option Plan does
not purport to be complete  and is qualified in its entirety by the terms of the
Amended  Option Plan. A copy of the Amended Option Plan is attached as Exhibit A
to this Proxy Statement.

The Amended Option Plan

     The Board of  Directors  adopted,  subject  to  stockholder  approval,  the
Amended  Option  Plan for the  purposes  of  securing  for the  Company  and its
stockholders  the benefits  arising from capital  stock  ownership by employees,
officers and directors of, and  consultants  or advisors to, the Company and its
parent  and  subsidiary  corporations  who are  expected  to  contribute  to the
Company's future growth and success.

     Administration.  The Amended Option Plan will be  administered by the Board
     --------------
of  Directors  of the Company or a committee  of the Board of  Directors,  whose
construction  and  interpretation  of the terms and  provisions  of the  Amended
Option Plan shall be final and conclusive.

     Eligibility.  Options  may be granted to  persons  who are,  at the time of
     -----------
grant,  employees,  officers or directors of, or consultants or advisors to, the
Company (each a "Participant").

     Options.  Options  granted  under the Amended  Option Plan may be Incentive
     -------
Stock Options  ("ISOs") or  nonqualified  stock  options.  An option  entitles a
Participant  to purchase  shares of Common  Stock from the Company at the option
price.  The option price may be paid in cash or with shares of Common Stock. The
purchase  price per share of stock  deliverable  upon the  exercise of an option
will be determined by the


                                      -19-

<PAGE>



Board of Directors, provided that in the case of nonqualified stock options, the
exercise  price  cannot be less than 50% of the fair market value of such stock,
as determined by the Board of Directors, at the time of grant of such option. In
the case of ISOs,  however,  the exercise  price cannot be less than 100% of the
fair market value of such stock, as determined by the Board of Directors, at the
time of grant of the option (110% of the fair market value in the case of an ISO
granted to an ten percent stockholder of the Company).  Options may be exercised
at such  time or  times  and  during  such  period  as may be set  forth  in the
agreement  evidencing  such  option,  subject to the  provisions  of the Amended
Option  Plan,  but the  maximum  term of an option is ten years from the date of
grant,  or five years from the date of grant in the case of an ISO  granted to a
ten percent stockholder.

     ISOs may only be granted to employees;  however, no employee may be granted
ISOs (under the Amended  Option Plan or any other plan of the Company)  that are
first  exercisable  in a calendar year for Common Stock having an aggregate fair
market value  (determined as of the  respective  date or dates of grant) of more
than  $100,000.  In  addition,  no  Participant  may be  granted  options in any
calendar year for more than 600,000 shares of Common Stock.

     Transferability. Awards granted under the Amended Option Plan are generally
     ---------------
non-transferable, except by will or the laws of descent and distribution.

     Share Authorization.  The maximum number of shares of Common Stock that may
     -------------------
be issued pursuant to options granted under the Amended Option Plan shall be the
greater of (i) 2,500,000 shares (which currently is the maximum amount permitted
prior to the amendments contemplated hereby) and (ii) (eighteen (18%) percent of
the total number of shares of Common Stock issued and outstanding  (assuming all
unexpired and outstanding  options are exercised and the Common Stock subject to
such  options  is  issued) as of the last day of the prior  calendar  year.  All
awards  made  under  the  Amended  Option  Plan  will be  evidenced  by  written
agreements  between the Company and the  Participant.  The share  limitation and
terms of outstanding  options will be adjusted,  as the Board of Directors deems
appropriate,  in the  event  of a stock  split,  combination,  reclassification,
recapitalization or other similar event. As of April 30, 1998,  approximately 60
individuals were eligible to participate in the Amended Option Plan.

     Termination and Amendment.  Unless terminated sooner in accordance with its
     -------------------------
terms,  the Amended Option Plan will  terminate,  with respect to ISOs, upon the
earlier  of (i) the  close of  business  on the day  next  preceding  the  tenth
anniversary  of the  original  date of adoption of 1994 Stock Option Plan by the
Board of Directors,  or (ii) the date on which all shares available for issuance
under the Amended Option Plan shall have been issued pursuant to the exercise or
cancellation of options granted under the Amended Option Plan. Unless terminated
sooner in accordance with its terms, the Amended Option Plan will terminate with
respect to options which are not ISOs on the date specified in (ii) above.

Certain Federal Income Tax Consequences.

     In general,  a participant will not recognize taxable income upon the grant
or exercise of an ISO.  However,  upon the exercise of an ISO, the excess of the
fair  market  value of the  shares  received  on the date of  exercise  over the
exercise  price of the shares will be treated as an  adjustment  to  alternative
minimum  taxable  income.  When a  participant  disposes  of shares  acquired by
exercise of an ISO,  the  participant's  gain (the  difference  between the sale
proceeds  and  the  price  paid by the  participant  for the  shares)  upon  the
disposition  will be taxed as capital  gain  provided the  participant  does not
dispose  of the shares  within two years  after the date of grant nor within one
year after the date of exercise,  and  exercises the option while an employee of
the Company or of a subsidiary of the Company or within three months


                                      -20-

<PAGE>



after  termination of employment for reasons other than death or disability.  If
the first condition is not met, the participant  generally will realize ordinary
income in the year of the disqualifying disposition.  If the second condition is
not met, the participant  generally will recognize ordinary income upon exercise
of the ISO.

     In general,  a participant  who receives a  nonqualified  stock option will
recognize no income at the time of the grant of the option.  Upon  exercise of a
nonqualified  stock option, a participant  will recognize  ordinary income in an
amount equal to the excess of the fair market value of the shares on the date of
exercise over the exercise  price of the option.  Special timing rules may apply
to a participant who is subject to Section 16(a) of the Exchange Act.

     The  employer  (either  the Company or its  affiliate)  will be entitled to
claim  a  federal  income  tax  deduction  on  account  of  the  exercise  of  a
nonqualified  option.  The amount of the deduction will be equal to the ordinary
income  recognized  by the  participant.  The employer will not be entitled to a
federal  income tax deduction on account of the grant or the exercise of an ISO.
The  employer  may claim a federal  income tax  deduction  on account of certain
disqualifying dispositions of Common Stock acquired upon the exercise of an ISO.

     The transfer of a non-qualified  stock option to a permitted  family member
will have no immediate tax consequences to the Company,  the participant or such
permitted family member.  Upon the subsequent exercise of the transferred option
by the permitted family member,  the participant will realize ordinary income in
an amount  measured by the difference  between the option exercise price and the
fair market value of the shares on the date of exercise,  and the employer  will
be entitled to a deduction in the same amount.  Any difference between such fair
market value and the price at which the permitted family member may subsequently
sell such shares will be treated as capital gain or loss to the permitted family
member,  long-term or short-term depending on the length of time the shares have
been held by the permitted family member.

     Section  162(m) of the Code places a limitation of $1,000,000 on the amount
of compensation payable to each of the named executive officers that the Company
may deduct for federal income tax purposes.  The limit does not apply to certain
performance-based  compensation paid under a plan that meets the requirements of
the Code and regulations promulgated  thereunder.  While the Amended Option Plan
generally  complies with the  requirements for  performance-based  compensation,
options  granted at less than 100% of fair market value under the Amended Option
Plan will not satisfy those requirements.

Board Recommendation

     The Board of  Directors  believes  the  Amended  Option Plan is in the best
interests of the Company and its  stockholders  and therefore  recommends a vote
FOR this proposal.




                                      -21-

<PAGE>



                             INDEPENDENT ACCOUNTANTS

     Coopers & Lybrand L.L.P. is currently serving as the Company's  independent
accountants.  Coopers & Lybrand L.L.P.  has served as the Company's  independent
accountants since 1993. Representatives of Coopers & Lybrand L.L.P. are expected
to be present at the Annual  Meeting.  They will have the  opportunity to make a
statement  if they  desire to do so and will also be  available  to  respond  to
appropriate questions from stockholders.


                                  OTHER MATTERS

     The Board of Directors  does not know of any other  matters  which may come
before the meeting.  However, if any other matters are properly presented to the
meeting,  it is the intention of the persons named in the accompanying  proxy to
vote, or otherwise act, in accordance with their judgment on such matters.

     All costs of  solicitation  of  proxies  will be borne by the  Company.  In
addition to solicitations by mail, the Company's directors, officers and regular
employees,  without additional  remuneration,  may solicit proxies by telephone,
telegraph,   facsimile  and  personal   interviews.   Brokers,   custodians  and
fiduciaries will be requested to forward proxy soliciting material to the owners
of stock held in their  names,  and the Company  will  reimburse  them for their
reasonable  out-of-pocket  expenses incurred in connection with the distribution
of proxy materials.

Deadline For Submission of Stockholder Proposals for the 1999 Annual Meeting

     Proposals  of  stockholders  intended  to be  presented  at the 1999 Annual
Meeting of Stockholders  must be received by the Company at its principal office
in Marlborough,  Massachusetts not later than December 31, 1998 for inclusion in
the proxy statement for that meeting.

                                 By Order of the Board of Directors



                                 JAMES B. MURPHY
                                 Secretary


April 30, 1998



     THE BOARD OF  DIRECTORS  ENCOURAGES  STOCKHOLDERS  TO ATTEND  THE  MEETING.
WHETHER OR NOT YOU PLAN TO ATTEND,  YOU ARE URGED TO  COMPLETE,  DATE,  SIGN AND
RETURN THE ENCLOSED PROXY IN THE ACCOMPANYING  ENVELOPE.  A PROMPT RESPONSE WILL
GREATLY  FACILITATE  ARRANGEMENTS  FOR THE MEETING AND YOUR  COOPERATION WILL BE
APPRECIATED.   STOCKHOLDERS  WHO  ATTEND  THIS  MEETING  MAY  VOTE  THEIR  STOCK
PERSONALLY EVEN THOUGH THEY HAVE SENT IN THEIR PROXIES.


                                      -22-


<PAGE>

                                                                       EXHIBIT A



                                 HEMASURE, INC.

                              AMENDED AND RESTATED
                             1994 STOCK OPTION PLAN


1.   Purpose.
     -------

     The purpose of this plan (the "Plan") is to secure for HemaSure  Inc.  (the
"Company")  and  its  shareholders  the  benefits  arising  from  capital  stock
ownership by employees,  officers and directors of, and  consultants or advisors
to, the Company and its parent and subsidiary  corporations  who are expected to
contribute to the Company's future growth and success.  Except where the context
otherwise requires,  the term "Company" shall include the parent and all present
and future  subsidiaries  of the Company as defined in Section 424(e) and 424(f)
of the Internal  Revenue Code of 1986,  as amended or replaced from time to time
(the  "Code").  Those  provisions  of the Plan which make  express  reference to
Section 422 shall apply only to Incentive Stock Options (as that term is defined
in the Plan).

2. Type of Options and Administration.
   -----------------------------------

     (a)  Types of  Options.  Options  granted  pursuant  to the  Plan  shall be
          -----------------
authorized  by action of the Board of  Directors  of the Company (or a Committee
designated by the Board of Directors) and may be either  incentive stock options
("Incentive  Stock Options") meeting the requirements of Section 422 of the Code
or  non-statutory  options  which are not intended to meet the  requirements  of
Section 422 of the Code.

     (b) Administration. The Plan will be administered by the Board of Directors
         --------------
of  the  Company,  whose  construction  and  interpretation  of  the  terms  and
provisions of the Plan shall be final and conclusive. The Board of Directors may
in its sole discretion  grant options to purchase shares of the Company's Common
Stock  ("Common  Stock")  and issue  shares  upon  exercise  of such  options as
provided  in the Plan.  The Board shall have  authority,  subject to the express
provisions of the Plan, to construe the  respective  option  agreements  and the
Plan, to  prescribe,  amend and rescind  rules and  regulations  relating to the
Plan, to determine the terms and provisions of the respective option agreements,
which  need  not be  identical,  and to make  all  other  determinations  in the
judgment of the Board of Directors necessary or desirable for the administration
of the  Plan.  The Board of  Directors  may  correct  any  defect or supply  any
omission or reconcile any  inconsistency  in the Plan or in any option agreement
in the manner and to the extent it shall deem  expedient  to carry the Plan into
effect and it shall be the sole and final judge of such expediency.  No director
or person acting pursuant to authority delegated by the Board of Directors shall
be liable for any action or determination under the Plan made in good faith. The
Board of Directors may, to the


                                       -1-

<PAGE>



full extent permitted by or consistent with applicable  laws,  Section 162(m) of
the Code or any regulations  thereunder or any successor  section of the Code or
regulations  thereunder  ("Section 162(m)") or regulations  (including,  without
limitation, applicable state law and Rule 16b-3 promulgated under the Securities
Exchange Act of 1934 (the "Exchange Act"), or any successor rule ("Rule 16b-3)),
delegate  any  or  all  of  its  powers  under  the  Plan  to a  committee  (the
"Committee")  appointed by the Board of  Directors,  and if the  Committee is so
appointed  all  references  to the Board of Directors in the Plan shall mean and
relate to such Committee.

     (c)  Applicability  of Rule 16b-3.  Those provisions of the Plan which make
          ----------------------------
express reference to Rule 16b-3 shall apply only to such persons as are required
to file reports under Section 16(a) of the Exchange Act (a "Reporting Person").

3.   Eligibility.
     -----------

     (a)  General.  Options  may be granted to persons  who are,  at the time of
          -------
grant,  employees,  officers or directors of, or consultants or advisors to, the
Company;  provided,  that the class of employees to whom Incentive Stock Options
may be granted  shall be limited to all  employees of the Company.  A person who
has been granted an option may, if he or she is otherwise  eligible,  be granted
additional  options if the Board of Directors  shall so  determine.  No employee
shall be granted options to purchase more than an aggregate of 600,000 shares of
Common  Stock under the Plan in any one calendar  year.  For this  purpose,  the
issuance of new options in substitution for outstanding  options shall be deemed
to constitute a new grant of additional options separate from the original grant
of the options that are to be canceled.

     (b) Grant of Options to Directors and Officers. The selection of a director
         ------------------------------------------
or officer (as the terms  "directors" and "officers" are defined for purposes of
Rule 16b-3) as a recipient  of an option shall be either (i)  determined  by (A)
the Board of Directors or (B) by two or more directors  having full authority to
act in the matter,  each of whom shall be a "non-employee  director"  within the
meaning of Rule 16b-3,  (ii) approved in advance or ratified by the shareholders
of the Company in accordance with Rule  16b-3(d)(3) or (iii) made in reliance on
another available exemption from the application of Section 16(b). To the extent
compliance  with  Section  162(m) of the Code is  desired,  in  addition  to the
foregoing if  applicable,  the selection of a "covered  employee" (as defined in
Section  162(m) of the Code) as a recipient of an option shall be made by two or
more  directors  each of whom is an  "outside  director"  as  defined in Section
162(m) of the Code.

4.   Stock Subject to Plan.
     ---------------------

     Subject to adjustment as provided in Section 15 below,  the maximum  number
of shares of Common Stock  reserved and available for issuance under the Amended
Option Plan shall be such  aggregate  number of Common  Stock as does not exceed
the greater of (i)  2,500,000  shares of Common  Stock and (ii)  eighteen  (18%)
percent of the total  number of shares of Common  Stock  issued and  outstanding
(assuming  all unexpired  and  outstanding  options are exercised and the Common
Stock  subject  to such  options  is  issued)  as of the last  day of the  prior
calendar year.


                                       -2-

<PAGE>



Notwithstanding the foregoing,  the maximum number of shares of Common Stock for
which Incentive Stock Options may be granted under the Amended Option Plan shall
not exceed 2,500,000 shares of Common Stock,  reduced by the aggregate number of
shares of Common Stock subject to then-outstanding  Incentive Stock Options. For
purposes of this limitation,  if any portion of the  then-outstanding  Incentive
Stock Options are  forfeited,  canceled,  reacquired  by the Company,  satisfied
without the  issuance of Common  Stock or  otherwise  terminated,  the shares of
Common Stock  underlying  such portion of the  Incentive  Stock Options shall be
added  back to the  shares of Common  Stock  available  for  issuance  under the
Amended Option Plan.

5.   Forms of Option Agreements.
     --------------------------

     As a condition to the grant of an option under the Plan,  each recipient of
an option shall execute an option agreement in such form not  inconsistent  with
the Plan as may be approved by the Board of  Directors.  Such option  agreements
may differ among recipients.

6.   Purchase Price.
     --------------

     (a) General.  The purchase  price per share of stock  deliverable  upon the
         -------
exercise of an option shall be determined  by the Board of Directors,  provided,
however,  that (i) in the case of an Incentive Stock Option,  the exercise price
shall  not be less  than  100% of the  fair  market  value  of  such  stock,  as
determined  by the Board of Directors,  at the time of grant of such option,  or
less than 110% of such fair market  value in the cause of options  described  in
Section  11(b),  and (ii) in the case of a  non-qualified  option,  the exercise
price  shall not be less than 50% of the fair  market  value of such  stock,  as
determined by the Board of Directors, at the time of grant of such option.

     (b) Payment of Purchase  Price.  Options granted under the Plan may provide
         --------------------------
for the  payment of the  exercise  price by  delivery  of cash or a check to the
order of the Company in an amount equal to the exercise  price of such  options,
or, to the extent provided in the applicable option  agreement,  (i) by delivery
to the  Company of shares of Common  Stock of the Company  already  owned by the
optionee having a fair market value equal in amount to the exercise price of the
options being exercised, (ii) by any other means (including, without limitation,
by delivery of a promissory  note of the  optionee  payable on such terms as are
specified by the Board of Directors) which the Board of Directors determines are
consistent with the purpose of the Plan and with applicable laws and regulations
(including, without limitation, the provisions of Rule 16b-3, Section 162(m) and
Regulation  T  promulgated  by  the  Federal  Reserve  Board)  or  (iii)  by any
combination  of such methods of payment.  The fair market value of any shares of
the  Company's  Common  Stock  or  other  non-cash  consideration  which  may be
delivered  upon  exercise  of an  option  shall be  determined  by the  Board of
Directors.



                                       -3-

<PAGE>



7.   Option Period.
     -------------

     Each option and all rights thereunder shall expire on such date as shall be
set forth in the  applicable  option  agreement,  except that, in the case of an
Incentive  Stock  Option,  such date shall not be later than ten years after the
date on which the option is granted and, in all cases,  options shall be subject
to earlier termination as provided in the Plan.

8.   Exercise of Options.
     -------------------

     Each option granted under the Plan shall be  exercisable  either in full or
in  installments  at such time or times and during  such  period as shall be set
forth in the agreement evidencing such option,  subject to the provisions of the
Plan.

9.   Nontransferability of Options.
     -----------------------------

     Incentive  Stock Options shall not be  assignable  or  transferable  by the
person to whom they are  granted,  either  voluntarily  or by  operation of law,
except by will or the laws of descent and distribution,  and, during the life of
the optionee,  shall be exercisable only by the optionee.  Non-statutory options
may be transferred with the consent of the Board of Directors to family members,
trusts  for family  members or  partnerships  in which all of the  partners  are
family members or family trusts of the option holder.

10.  Effect of Termination of Employment or Other Relationship.
     ----------------------------------------------------------

     Except as  provided  in Section  11(d)  with  respect  to  Incentive  Stock
Options, and subject to the provisions of the Plan, the Board of Directors shall
determine  the period of time during  which an optionee  may  exercise an option
following (i) the termination of the optionee's employment or other relationship
with the Company or (ii) the death or disability  of the optionee.  Such periods
shall be set forth in the agreement evidencing such option.

11.  Incentive Stock Options.
     -----------------------

     Options  granted  under the Plan which are intended to be  Incentive  Stock
Options shall be subject to the following additional terms and conditions:

     (a) Express Designation. All Incentive Stock Options granted under the Plan
         -------------------
shall, at the time of grant,  be  specifically  designated as such in the option
agreement covering such Incentive Stock Options.

     (b) 10%  Shareholder.  If any employee to whom an Incentive Stock Option is
         ----------------
to be granted  under the Plan is, at the time of the grant of such  option,  the
owner of stock  possessing  more than 10% of the total combined  voting power of
all classes of stock of the Company  (after taking into account the  attribution
of stock  ownership  rules of Section  424(d) of the Code),  then the  following
special  provisions shall be applicable to the Incentive Stock Option granted to
such individual:


                                       -4-

<PAGE>



          (i) The purchase  price per share of the Common Stock  subject to such
     Incentive Stock Option shall not be less than 110% of the fair market value
     of one share of Common Stock at the time of grant: and

          (ii) the option  exercise  period shall not exceed five years from the
     date of grant.

     (c) Dollar  Limitation.  For so long as the Code shall so provide,  options
         ------------------
granted to any  employee  under the Plan (and any other  incentive  stock option
plans of the Company) which are intended to constitute  Incentive  Stock Options
shall not constitute Incentive Stock Options to the extent that such options, in
the aggregate,  become  exercisable  for the first time in any one calendar year
for shares of Common Stock with an aggregate fair market value (determined as of
the respective date or dates of grant) of more than $100,000.

     (d)  Termination of Employment,  Death or  Disability.  No Incentive  Stock
          ------------------------------------------------
Option may be exercised unless,  at the time of such exercise,  the optionee is,
and has been continuously since the date of grant of his or her option, employed
by the  Company,  except that:

          (i) an Incentive  Stock  Option may be exercised  within the period of
     three months  after the date the optionee  ceases to be an employees of the
     Company (or within such lesser period as may be specified in the applicable
     option agreement(, provided, that the agreement with respect to such option
     may  designate a longer  exercise  period and that the exercise  after such
     three-month  period  shall be treated as the  exercise  of a  non-statutory
     option under the Plan;

          (ii) if the optionee  dies while in the  employee of the  Company,  or
     within three months after the optionee  ceases to be such an employee,  the
     Incentive  Stock  Option  may be  exercised  by the  person  to  whom it is
     transferred  by will or the laws of  descent  and  distribution  within the
     period of one year after the date of death (or within such lesser period as
     may be specified in the applicable option agreement); and

          (iii) if the optionee  becomes disabled (within the meaning of Section
     22(e)(3)  of the  Code or any  successor  provision  thereto)  while in the
     employ of the Company,  the Incentive Stock Option may be exercised  within
     the  period of one year  after the date the  optionee  ceases to be such an
     employee because of such disability (or within such lesser period as may be
     specified in the applicable option agreement).

For all  purposes  of the Plan and any option  granted  hereunder,  "employment"
shall be defined in accordance with the provisions of Section  1.421-7(h) of the
Income Tax  Regulations  (or any  successor  regulations).  Notwithstanding  the
foregoing  provisions,  no Incentive  Stock  Option may be  exercised  after its
expiration date.

     (e) Savings  Clause.  To the extent any Incentive  Stock Option fails to be
         ---------------
treated as an Incentive  Stock  Option,  it shall be treated as a  non-statutory
stock option.

12.  Additional Provisions.
     ---------------------



                                       -5-

<PAGE>



     (a) Additional Option  Provisions.  The Board of Directors may, in its sole
         -----------------------------
discretion,  include additional provisions in option agreements covering options
granted under the Plan,  including without limitation  restrictions on transfer,
repurchase  rights,  commitments  to pay cash bonuses,  to make,  arrange for or
guaranty  loans or to transfer  other  property to  optionees  upon  exercise of
options,  or such  other  provisions  as shall  be  determined  by the  Board of
Directors;  provided that such additional  provisions  shall not be inconsistent
with any other  term or  condition  of the Plan and such  additional  provisions
shall not cause any  Incentive  Stock Option  granted  under the Plan to fail to
qualify as an Incentive  Stock  Option  within the meaning of Section 422 of the
code.

     (b) Acceleration,  Extension,  Etc. The Board of Directors may, in its sole
         ------------------------------
discretion,  (i)  accelerate  the date or dates on which  all or any  particular
option or options  granted  under the Plan may be  exercised  or (ii) extend the
dates during which all, or any  particular,  option or options granted under the
Plan  may be  exercised;  provided,  however,  that no such  extension  shall be
permitted  if it would cause the Plan to fail to comply with  Section 422 of the
Code or with Rule  16b-3 or cause any option  granted  under the Plan to fail to
qualify as performance-based compensation within the meaning of Section 162(m).

13.  General Restrictions.
     --------------------

     (a) Investment Representations.  The Company may require any person to whom
         --------------------------
an option is granted,  as a condition of exercising such option, to give written
assurances in substance and form  satisfactory to the Company to the effect that
such person is acquiring  the Common Stock  subject to the option for his or her
own account for  investment  and not with any  present  intention  of selling or
otherwise  distributing the same, and to such other effects as the Company deems
necessary or appropriate  in order to comply with federal and  applicable  state
securities  laws, or with  covenants or  representations  made by the Company in
connection with any public offering of its Common Stock.

     (b) Compliance  With  Securities  Laws. Each option shall be subject to the
         ----------------------------------
requirement  that if, at any time,  counsel to the Company shall  determine that
the listing,  registration or qualification of the shares subject to such option
upon any  securities  exchange or under any state or federal law, or the consent
of approval of any  governmental  or regulatory  body, or that the disclosure of
non-public  information or the  satisfaction of any other condition is necessary
as a condition  of, or in  connection  with,  the issuance or purchase of shares
thereunder,  such option may not be exercised,  in whole or in part, unless such
listing,  registration,  qualification,  consent or approval, or satisfaction of
such condition shall have been effected or obtained on conditions  acceptable to
the Board of Directors. Nothing herein shall be deemed to require the Company to
apply  for or to obtain  such  listing,  registration  or  qualification,  or to
satisfy such condition.

14. Rights as a Shareholder.
    -----------------------

     The holder of an option shall have no rights as a shareholder  with respect
to any shares covered by the option (including,  without limitation,  any rights
to receive dividends or non-cash


                                       -6-

<PAGE>



distributions  with  respect to such shares ) until the date of issue of a stock
certificate  to him or her for  such  shares.  No  adjustment  shall be made for
dividends  or other  rights for which the record  date is prior to the date such
stock certificate is issued.

15.  Adjustment Provisions for Recapitalizations and Related Transactions.
     ---------------------------------------------------------------------

     (a) General. If, through or as a result of any merger, consolidation,  sale
         -------
of  all or  substantially  all of the  assets  of the  Company,  reorganization,
recapitalization,  reclassification,  stock dividend, stock split, reverse stock
split or other similar  transaction,  (i) the outstanding shares of Common Stock
are increased,  decreased or exchanged for a different  number or kind of shares
or  other  securities  of the  Company,  or  (ii)  additional  shares  or new or
different shares or other securities of the Company or other non-cash assets are
distributed with respect to such shares of Common Stock or other securities,  an
appropriate and  proportionate  adjustment may be made in (x) the maximum number
and kind of shares reserved for issuance under the Plan, (y) the number and kind
of shares or other securities subject to any then outstanding  options under the
Plan, and (z) the price for each share subject to any then  outstanding  options
under the Plan,  without changing the aggregate  purchase price as to which such
options remain exercisable.  Notwithstanding the foregoing,  no adjustment shall
be made pursuant to this Section 15 if such  adjustment  would cause the Plan to
fail to comply with Section 422 of the Code or with Rule 16b- 3.

     (b) Board Authority to Make Adjustments. Any adjustments under this Section
         -----------------------------------
15 will be  made by the  Board  of  Directors,  whose  determination  as to what
adjustments,  if any, will be made and the extent thereof will be final, binding
and conclusive. No fractional shares will be issued under the Plan on account of
any such adjustments.

16.  Merger, Consolidation, Asset Sale, Liquidation, etc.
     ----------------------------------------------------

     (a) General.  Subject to Section 16(c), in the event of a consolidation  or
         -------
merger or sale of all or substantially all of the assets of the Company in which
outstanding  shares of Common Stock are exchanged for securities,  cash or other
property  of any  other  corporation  or  business  entity  or in the event of a
liquidation of the Company,  the Board of Directors of the Company, or the board
of directors of any corporation  assuming the obligations of the Company, may in
its discretion, take any one or more of the following actions, as to outstanding
options:  (i) provide that such options shall be assumed,  or equivalent options
shall  be  substituted,  by  the  acquiring  or  succeeding  corporation  (or an
affiliate  thereof),  provided that any such options  substituted  for Incentive
Stock Options shall meet the  requirements  of Section 424(a) of the Code,  (ii)
upon written notice to the optionees,  provide that all unexercised options will
terminate  immediately  prior to the  consummation  of such  transaction  unless
exercised by the optionee  (to the extent then  exercisable)  within a specified
period  following  the date of such  notice  and  (iii) in the event of a merger
under the terms of which holders of the Common Stock of the Company will receive
upon  consummation  thereof a cash  payment  for each share  surrendered  in the
merger (the "Merger Price"), make or provide for a cash payment to the optionees
equal to the difference  between (A) the Merger Price times the number of shares
of Common Stock subject to such outstanding options


                                       -7-

<PAGE>



(to the extent then exercisable at prices not in excess of the Merger Price) and
(B) the aggregate exercise price of all such outstanding options in exchange for
the termination of such options.

     (b)  Substitute  Options.  The Company may grant  options under the Plan in
          -------------------
substitution  for options held by employees  of another  corporation  who become
employees of the Company,  or a  subsidiary  of the Company,  as the result of a
merger or  consolidation  of the  employing  corporation  with the  Company or a
subsidiary of the Company,  or as a result of the acquisition by the Company, or
one of its subsidiaries,  of property or stock of the employing corporation. The
Company  may  direct  that  substitute  options  be  granted  on such  terms and
conditions as the Board of Directors considers appropriate in the circumstances.

     (c)  Change  in  Control.  Notwithstanding  any other  provision  contained
          -------------------
herein,  in the event of a "Change in Control" of the Company (as defined below)
each outstanding  option under the Plan held by a person who is then an employee
of the Company shall immediately become exercisable in full. For purposes of the
Plan, a "Change in Control"  shall be deemed to have occurred only if any of the
following  events  occurs:  (i) any  "person",  as such term is used in Sections
13(d) and 14(d) of the  Exchange  Act (other  than the  Company,  any trustee or
other  fiduciary  holding  securities  under  an  employee  benefit  plan of the
Company,  or any corporation owned directly or indirectly by the stockholders of
the Company in substantially  the same proportion as their ownership of stock of
the  Company),  is or becomes the  "beneficial  owner" (as defined in Rule 13d-3
under the Exchange Act),  directly or  indirectly,  of securities of the Company
representing  50% or more of the  combined  voting power of the  Company's  then
outstanding securities; (ii) the stockholders of the Company approve a merger or
consolidation of the Company with any other corporation,  other than a merger or
consolidation  which  would  result  in the  voting  securities  of the  Company
outstanding  immediately  prior  thereto  continuing  to  represent  (either  by
remaining  outstanding  or by being  converted  into  voting  securities  of the
surviving  entity)  more than 50% of the  combined  voting  power of the  voting
securities of the Company or such surviving entity outstanding  immediately afer
such merger or  consolidation;  (iii) the  stockholders of the Company approve a
plan of  complete  liquidation  of the Company or an  agreement  for the sale or
disposition by the Company of all or substantially  all of the Company's assets;
or (iv)  individuals who, on the date on which the Plan was adopted by the Board
of Directors,  constituted the Board of Directors of the Company,  together with
any new director  whose  election by the Board of Directors  or  nomination  for
election  by the  Company's  stockholders  was  approved by a vote of at least a
majority of the directors then still in office who were directors on the date on
which  the Plan was  adopted  by the Board of  Directors  or whose  election  or
nomination  was  previously  so approved,  cease for any reason to constitute at
least a majority of the Board of Directors.

17.  No Special Employment Rights.
     ----------------------------

     Nothing  contained  in the  Plan or in any  option  shall  confer  upon any
optionee any right with respect to the  continuation of his or her employment by
the Company or interfere in any way with the right of the Company at any time to
terminate  such  employment or to increase or decrease the  compensation  of the
optionee.


                                       -8-

<PAGE>



18.  Other Employee Benefits.
     -----------------------

     Except  as  to  plan  which  by  their  terms   include   such  amounts  as
compensation,  the  amount  of any  compensation  deemed  to be  received  by an
employee as a result of the exercise of an option or the sale or shares received
upon such exercise will not  constitute  compensation  with respect to which any
other  employee  benefits of such employee are  determined,  including,  without
limitation, benefits under any bonus, pension, profit-sharing, life insurance or
salary  continuation  plan, except as otherwise  specifically  determined by the
Board of Directors.

19.  Amendment of the Plan.
     ---------------------

     (a) The Board of Directors may at any time,  and from time to time,  modify
or amend the Plan in any respect, except that if at any time the approval of the
shareholders  of the  Company is required  under  Section 422 of the Code or any
successor  provision  with respect to  Incentive  Stock  Options,  or under Rule
16b-3, or is required to ensure that any compensation  resulting from any option
under the Plan is  deductible  for federal  income tax  purposes  under  Section
162(m).  The Board of Directors  may not effect such  modification  or amendment
without such approval.

     (b) The termination or any modification or amendment of the Plan shall not,
without the  consent of an  optionee,  affect his or her rights  under an option
previously granted to him or her. With the consent of the optionee affected, the
Board of  Directors  may amend  outstanding  option  agreements  in a manner not
inconsistent with the Plan. The Board of Directors shall have the right to amend
or  modify  (i) the  terms  and  provisions  of the Plan and of any  outstanding
Incentive  Stock  Options  granted  under the Plan to the  extent  necessary  to
qualify any or all such options for such favorable  federal income tax treatment
(including  deferral of taxation  upon  exercise)  as may be afforded  incentive
stock options under Section 422 of the Code and (ii) the terms and provisions of
the Plan and of any  outstanding  option to the extent  necessary  to ensure the
qualification of the Plan under Rule 16b-3 or to ensure the deductibility of any
compensation resulting from any option under 162(m).



                                       -9-

<PAGE>




20.  Withholding.
     -----------

     (a) The Company  shall have the right to deduct  from  payments of any kind
otherwise  due to the  optionee  any  federal,  state or local taxes of any kind
required by law to be withheld  with respect to any shares  issued upon exercise
of options under the Plan.  Subject to the prior approval of the Company,  which
may be withheld by the Company in its sole discretion, the optionee may elect to
satisfy  such  obligations,  in whole or in part,  (i) by causing the Company to
withhold shares of Common Stock otherwise  issuable  pursuant to the exercise of
an option or (ii) by  delivering  to the Company  shares of Common Stock already
owned by the  optionee.  The shares so delivered  or withheld  shall have a fair
market value equal to such withholding obligation.  The fair market value of the
shares used to satisfy such  withholding  obligation  shall be determined by the
Company  as of  the  date  that  the  amount  of  tax  to be  withheld  is to be
determined.  An optionee who has made an election pursuant to this Section 20(a)
may only satisfy his or her  withholding  obligation with shares of Common Stock
which are not  subject to any  repurchase,  forfeiture,  unfulfilled  vesting or
other similar requirements.

     (b)  Notwithstanding  the foregoing,  in the case of a Reporting Person, no
election to use shares for the payment of  withholding  taxes shall be effective
unless made in compliance with any applicable requirements of Rule 16b-3.

21.  Cancellation and New Grant of Options, Etc.
     -------------------------------------------

     The Board of directors shall have the authority to effect,  at any time and
from  time  to  time,  with  the  consent  of the  affected  optionees,  (i) the
cancellation of any or all  outstanding  options under the Plan and the grant in
substitution  therefor  of new  options  under  the  Plan  covering  the same or
different  numbers of shares of Common stock and having an option exercise price
per share which may be lower or higher than the exercise  price per share of the
canceled  options or (ii) the amendment of the terms of any and all  outstanding
options  under the Plan to provide an option  exercise  price per share which is
higher  or  lower  than  the  then-current  exercise  price  per  share  of such
outstanding options.

22.  Effective Date and Duration of the Plan.
     ----------------------------------------

     (a) Effective  Date.  The Plan shall become  effective  when adopted by the
         ---------------
Board of Directors,  but no Incentive  Stock Option granted under the Plan shall
become  exercisable  unless and until the Plan shall have been  approved  by the
Company's  shareholders.  If such  shareholder  approval is not obtained  within
twelve  months  after the date of the  Board's  adoption  of the Plan no options
previously granted under the Plan shall be deemed to be Incentive Stock Options,
options previously granted to covered employees, directors or officers shall not
vest and  shall  terminate  and no  Incentive  Stock  Options  shall be  granted
thereafter nor shall any options be granted  thereafter to covered  employees or
officers. Amendments to the Plan not requiring shareholder approval shall become
effective  when  adopted  by  the  Board  of  Directors;   amendments  requiring
shareholder  approval (as provided in Section 19) shall  become  effective  when
adopted by the


                                      -10-

<PAGE>


Board of Directors, but no Incentive Stock Option granted after the date of such
amendment  and no option  granted to any covered  employee,  director or officer
after the date of such amendment  shall become  exercisable  (to the extent that
(i) such  amendment to the Plan was required to enable the Company to grant such
Incentive Stock Option to a particular optionee or (ii) shareholder  approval of
such amendment to the Plan was required to ensure the continued qualification of
the Plan under Section 16b-3 or Section 162(m) or to ensure the deductibility of
any compensation resulting from any option under Section 162(m) unless and until
such amendment shall have been approved by the Company's  shareholders.  If such
shareholder  approval  is not  obtained  within  twelve  months  of the  Board's
adoption of such amendment,  (i) any Incentive Stock Options granted on or after
the date of such amendment  shall terminate to the extent that such amendment to
the Plan was required to enable the Company to grant such option to a particular
optionee and (ii) any option granted to a covered employee,  director or officer
on or after  the date of such  amendment  shall  terminate  to the  extent  that
shareholder  approval  of  such  amendment  was  required  to  ensure  continued
qualification  of the Plan under  Rule 16b-3 or Section  162(m) or to ensure the
deductibility  of any  compensation  resulting  from any  option  under  Section
162(m). Subject to this limitation, options may be granted under the Plan at any
time after the effective  date and before the date fixed for  termination of the
Plan.

     (b)  Termination.  Unless sooner  terminated in accordance with Section 16,
          -----------
the Plan shall  terminate,  with respect to Incentive  Stock  Options,  upon the
earlier  of (i) the  close of  business  on the day  next  preceding  the  tenth
anniversary  of the date of its adoption by the Board of Directors,  or (ii) the
date on which all shares  available for issuance  under the Plan shall have been
issued  pursuant to the exercise or  cancellation  of options  granted under the
Plan.  Unless sooner  terminated  in accordance  with Section 16, the Plan shall
terminate  with respect to options which are not Incentive  Stock Options on the
date specified in (ii) above. If the date of termination is determined under (i)
above,  then options  outstanding  on such date shall continue to have force and
effect in accordance  with the  provisions of the  instruments  evidencing  such
options.

23.  Provision for Foreign Participants.
     ----------------------------------

     The Board of Directors  may,  without  amending the Plan,  modify awards or
options granted to participants  who are foreign  nationals or employed  outside
the United  States to  recognize  differences  in laws,  rules,  regulations  or
customs of such foreign jurisdictions with respect to tax, securities, currency,
employee benefit or other matters.

                                    Adopted by the Board of Directors on
                                    April 3, 1998


                                      -11-

<PAGE>




                                  HEMASURE INC.
                    PROXY SOLICITED BY THE BOARD OF DIRECTORS
                  Annual Meeting of Stockholders - May 26, 1998

          Those signing on the reverse side, revoking any prior proxies, hereby
appoint(s) Timothy J. Barberich and John F. McGuire, or each or any of them,
with full power of substitution, as proxies for those signing on the reverse
side to act and vote at the 1998 Annual Meeting of Stockholders of HemaSure
Inc., and at any adjournments thereof as indicated upon all matters referred to
on the reverse side and described in the Proxy Statement for the Meeting, and,
in their discretion, upon any other matters which may properly come before the
Meeting.

          This proxy when properly executed will be voted in the manner directed
by the undersigned stockholder(s). If no other indication is made, the proxies
shall vote "For" proposal numbers 1, 2, 3 and 4.

          A vote FOR the director nominiees and FOR proposal numbers 2, 3 and 4
is recommended by the Board of Directors.

              PLEASE VOTE, DATE, AND SIGN ON OTHER SIDE AND RETURN
                          PROMPTLY IN ENCLOSED ENVELOP.



<PAGE>


/ x/ Please mark your votes
     as in this example



1. ELECTION OF   for all nominees     Withheld authority to
   DIRECTOR      listed at right      vote for all nominees
                                      listed at right
                     / /                   / /   Nominees:  Timothy J. Barberich
                                                            David S. Barlow
                                                            Roff S. Stutz
                                                            John F. McGuire
                                                            Justin E. Doheny

INSTRUCTIONS: To withhold authority to vote for individual nominee(s) strike a
line through each such nominee's name in the list at right. Your shares will be
voted for the remaining nominee(s).




2.   Approval of the Amendment to the                FOR     AGAINST     ABSTAIN
     Company's 1995 Employee Stock                  /  /       /  /         /  /
     Purchase Plan.

3.   Approval of Amendments to the                  /  /       /  /         /  /
     Company's 1994 Stock Option Plan.

4.   To transact such other business as may         /  /       /  /         /  /
     properly come before the meeting or any
     adjournment thereof.


Please read the reverse side of this card.

PLEASE VOTE, SIGN, DATE AND RETURN THE PROXY CARD PROMPLY
USING THE ENCLOSED ENVELOPE


HAS YOUR ADDRESS CHANGED?                            DO YOU HAVE COMMENTS?

- --------------------------------------------------------------------------------


- --------------------------------------------------------------------------------


SIGNATURE ___________________________ DATE __________________

NOTE:    Please sign this proxy exactly as your name appears hereon. Joint
         owners should each sign personally. Trustees or other Fiduciaries
         should indicate the capacity in which they sign. If a corporation or
         partnerships signature should be that of an authorized officer who
         should give his or her title.





© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission