PRICE T ROWE FIXED INCOME SERIES INC
497, 2000-05-01
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May 1, 2000

Zandra Y. Bailes, Esquire
Office of Insurance Products
Division of Investment Management
U.S. Securities & Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549

Re:  T. Rowe Price Fixed Income Series, Inc.
     consisting of two separate portfolios:
       T. Rowe Price Limited-Term Bond Portfolio
       T. Rowe Price Prime Reserve Portfolio
     File Nos.: 033-52749/811-07153

Dear Ms. Bailes:

This letter will serve as our filing under provisions of Rule 497 of the
Securities Act of 1933. We are writing to inform you that there have been no
changes to the Funds' Prospectuses and Statements of Additional Information that
were filed under Rule 485(b) as part of Post-Effective Amendment No. 9 on April
24, 2000.

The Prospectuses and Statements of Additional Information went effective on May
1, 2000. These documents will be used for the offer and sale of Fund shares.

Sincerely,
/s/Forrest R. Foss
Forrest R. Foss


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