TRIPOS INC
DEF 14A, 1999-04-09
PREPACKAGED SOFTWARE
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                      SCHEDULE 14A INFORMATION

          Proxy Statement Pursuant to Section 14(a) of the
                   Securities Exchange Act of 1934

Filed by the Registrant [X]
Filed by a Party other than the Registrant [ ]

Check the appropriate box:

[ ]  Preliminary Proxy Statement
[ ]  Confidential, for Use of the Commission Only (as permitted by
     Rule 14a-6(e)(2))
[X]  Definitive Proxy Statement
[ ]  Definitive Additional Materials
[ ]  Soliciting Material Pursuant to Sec. 240.14a-11(c) or Sec.240.14a-12

                            TRIPOS, INC.
          (Name of Registrant as Specified In Its Charter)


     (Name of Person(s) Filing Proxy Statement if other than the
                             Registrant)

Payment of Filing Fee (Check the appropriate box):

[X]   No fee required.
[ ]   Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

   1)  Title of each class of securities to which transaction applies:

   2)  Aggregate number of securities to which transaction applies:
   
   3)  Per unit price or other underlying value of transaction
   computed pursuant to Exchange Act Rule 0-11 (Set forth the amount
   on which the filing fee is calculated and state how it was determined):

   4) Proposed maximum aggregate value of transaction:

   5) Total fee paid:

[ ]     Fee paid previously with preliminary materials.

[ ]     Check box if any part of the fee is offset as provided by
Exchange Act Rule 0-11(a)(2) and identify the filing for which the
offsetting fee was paid previously.  Identify the previous filing by
registration statement number, or the Form or Schedule and the date
of its filing.

    1) Amount Previously Paid:

    2) Form, Schedule or Registration Statement No.:

    3) Filing Party:

    4) Date Filed:


                                  
                           <Company Logo>
                                  
                            TRIPOS, INC.
                                  
                                  
              NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
                       To Be Held May 11, 1999
                                  
To Our Shareholders:

      The  Annual  Meeting  of Shareholders  of  Tripos,  Inc.  (the
"Company") will be held at the World Trade Center St. Louis, 121  South
Meramec,  10th  Floor, Clayton, Missouri, 63105 at 1:00  p.m.  local
time on May 11, 1999 for the following purposes:

     1.   To elect directors to serve for the ensuing year or until their
          successors are elected;
     
     2.   To act upon such other business as may properly come before the
          Annual Meeting or at any adjournments or postponements thereof.

    The Board of Directors has fixed the close of business on April 2,
1999  as the record date for determining those shareholders  who will
be entitled to notice of and to vote at the Annual Meeting.

     Representation of at least a majority of all outstanding shares
of  Common Stock of the Company is required to constitute a  quorum.
Accordingly, it is important that your shares be represented at  the
meeting.   WHETHER  OR  NOT YOU PLAN TO ATTEND THE  ANNUAL  MEETING,
PLEASE COMPLETE, DATE AND SIGN THE ENCLOSED PROXY FORM AND RETURN IT
IN  THE  ENCLOSED ENVELOPE.  You may revoke your proxy at  any  time
prior to the time it is voted.  If you attend the Annual Meeting and
vote  by  ballot, your proxy will be revoked automatically and  only
your vote at the Annual Meeting will be counted.

                                             Sincerely,


                                             /s/ Colleen A. Martin
                                             Colleen A. Martin
                                             Corporate Secretary

St. Louis, Missouri
April 9, 1999


                                  
                                  
         Shareholders Should Read the Entire Proxy Statement
           Carefully Prior to Returning Their Proxy Forms
                                  
                           PROXY STATEMENT
                                 FOR
                  ANNUAL MEETING OF SHAREHOLDERS OF
                            TRIPOS, INC.
                                  
                       To Be Held May 11, 1999
                                  
      This  Proxy  Statement  is furnished in  connection  with  the
solicitation by the Board of Directors of Tripos, Inc. ("Tripos"  or
the  "Company")  of  proxies to be voted at the  Annual  Meeting  of
Shareholders which will be held at 1:00 p.m. local time on  May  11,
1999  at  the  World Trade Center St. Louis, 121  S.  Meramec,  10th
Floor,   Clayton,   Missouri  63105,  or  at  any  adjournments   or
postponements   thereof,  for  the  purposes  set   forth   in   the
accompanying Notice of Annual Meeting of Shareholders.   This  Proxy
Statement and the accompanying proxy form are first being mailed  to
shareholders on or about April 9, 1999.

                   VOTING RIGHTS AND SOLICITATION
                                  
      The close of business on April 2, 1999 was the record date for
shareholders  entitled  to  notice of and  to  vote  at  the  Annual
Meeting.   As  of that date, Tripos had 3,256,722 shares  of  Common
Stock,  $.01  par value per share (the "Common Stock"),  issued  and
outstanding.   All  of  the  shares of the  Company's  Common  Stock
outstanding  on the record date are entitled to vote at  the  Annual
Meeting, and shareholders of record entitled to vote at the  meeting
will  have one (1) vote for each share so held on the matters to  be
voted upon.

      Shares of the Company's Common Stock represented by proxies in
the  accompanying form that are properly executed  and  returned  to
Tripos  will  be  voted  at the Annual Meeting  of  Shareholders  in
accordance  with  the shareholders' instructions contained  therein.
In  the absence of contrary instructions, shares represented by such
proxies  will be voted FOR the election of each of the directors  as
described  herein  under  "Proposal 1  --  Election  of  Directors".
Management  does  not know of any matters to be  presented  in  this
Annual  Meeting  other than those set forth in this Proxy  Statement
and  in  the  Notice  accompanying this Proxy Statement.   If  other
matters  should properly come before the meeting, the proxy  holders
will vote on such matters in accordance with their best judgement.

     Any shareholder has the right to revoke his or her proxy at any
time  before it is voted.  A proxy may be revoked either by  written
notice  to the Secretary of the Company or by attending the  meeting
and voting in person.
     
     A  majority of the outstanding shares of Common Stock,  present
in  person or represented by proxy, will constitute a quorum for the
transaction  of business at the Annual Meeting.  Shares  represented
by  proxies which are marked to "withhold authority" with respect to
the  election  of  any one or more of the nominees for  election  of
directors and proxies which are marked to "abstain" with respect  to
any  other matter will be counted for the purpose of determining the
number  of  shares  represented by proxy  at  the  meeting  and  the
presence or absence of a quorum.
     
     The  affirmative vote of a plurality of the shares present,  in
person  or  by  proxy, at the Annual Meeting, is required  to  elect
directors.   "Plurality"  means that the nominees  who  receive  the
largest  number  of  votes  cast,  up  to  the  maximum  number   of
directorships to be filled, will be elected.  Consequently,  marking
the proxy statement to withhold a vote for one or more nominees does
not  have  the effect of a vote against that director(s),  but  will
have an effect on the number of votes cast in the election and could
effect the outcome.
     
     If no specification is made on a duly executed proxy, the proxy
will  be voted FOR election of the directors nominated by the  Board
of Directors.  Abstentions and broker non-votes are each included in
the  determination  of  the  number of  shares  present  for  quorum
purposes.  Abstentions are counted in tabulations of the votes  cast
on proposals presented to shareholders, whereas broker non-votes are
not  counted for purposes of determining whether a proposal has been
approved.
     
      The entire cost of soliciting proxies will be borne by Tripos.
Proxies will be solicited principally through the use of the  mails,
but,  if  deemed  desirable,  may  be  solicited  personally  or  by
telephone, telefax or special letter by officers and regular  Tripos
employees for no additional compensation.  The Board of Directors of
the  Company has engaged ChaseMellon Shareholder Services to provide
routine  advice  and  services.  Arrangements have  been  made  with
brokerage  houses and other custodians, nominees and fiduciaries  to
send  proxies  and proxy materials to the beneficial owners  of  the
Company's  Common  Stock, and such persons shall be  reimbursed  for
their reasonable expenses.
                                  
                                  
                        SHAREHOLDER PROPOSALS
                                  
      Proposals of Shareholders intended to be presented at the 2000
Annual  Meeting  must  be  received by the  Company  no  later  than
December  11,  1999, for inclusion in the Company's proxy  statement
and  proxy  relating  to that meeting.  Upon  receipt  of  any  such
proposal, the Company will determine whether or not to include  such
proposal  in  the  proxy  statement and  proxy  in  accordance  with
regulations governing the solicitation of proxies.

     In order for a Shareholder to nominate a candidate for director
under the Company's Bylaws, timely notice of the nomination must  be
received by the Company in advance of the meeting.  Such notice must
be  received  by the Company no later than March 11,  2000,  and  no
earlier  than February 11, 2000.  The Shareholder filing the  notice
of nomination must describe various matters regarding the nominee as
set  forth  in  the Company's Bylaws, including such information  as
name, address, occupation and shares held.

     Under the Company's Bylaws, in order for a Shareholder to bring
other  business before a Shareholder meeting, timely notice must  be
received  by  the  Company within the time limits  described  above.
Such notice must include a description of the proposed business, the
reasons  therefor,  and  other matters specified  in  the  Company's
Bylaws.   These  requirements are separate from and in  addition  to
requirements a Shareholder must meet to have a proposal included  in
the  Company's proxy statement and proxy.  The foregoing time limits
also  apply in determining whether notice is timely for purposes  of
rules adopted by the Securities and Exchange Commission relating  to
the exercise of discretionary voting authority.

  In  each  case  the notice must be given to the Secretary  of  the
Company,  whose  address  is  1699 South  Hanley  Road,  St.  Louis,
Missouri  63144.



             MATTERS TO BE CONSIDERED AT ANNUAL MEETING
                                  
                             PROPOSAL 1:
                                  
                        ELECTION OF DIRECTORS

      The  nominees for the Board of Directors are set forth  below.
The proxy holders intend to vote all proxies received by them in the
accompanying form for the nominees for directors listed  below.   In
the  event any nominee is unable or declines to serve as a  director
at the time of the Annual Meeting, either the size of the Board will
be reduced or the proxies will be voted for any nominee who shall be
designated  by the present Board of Directors to fill  the  vacancy.
In  the event that additional persons are nominated for election  as
directors, the proxy holders intend to vote all proxies received  by
them  for  the nominees listed below.  As of the date of this  Proxy
Statement, the Board of Directors is not aware of any nominee who is
unable  or will decline to serve as a director.  The directors  will
serve for a one year term, or until their respective successors  are
duly elected and qualified.  Directors are elected by a plurality of
the votes present in person or represented by proxy and entitled  to
vote at the meeting.

Nominees to Board of Directors
       Name        Director   Age         Name            Director   Age
                    Since                                  Since
                                                               
Ralph S. Lobdell     1994     55   Alfred Alberts           1997     67
Stewart Carrell      1994     65   John P. McAlister,III    1994     50
Gary Meredith        1996     64   Ferid Murad              1996     62

     Ralph  S.  Lobdell  has  served as Chairman  of  the  Board  of
Directors of the Company since June 1994.  Mr. Lobdell received  his
Bachelor  of Science degree from the U.S. Naval Academy in 1965  and
his  Master  of Business Administration from Stanford University  in
1972.   Mr.  Lobdell worked for First Chicago Corporation from  1972
through  1977, initially on the parent company staff  and  then  its
venture  capital subsidiaries.  In 1977, Mr. Lobdell  joined  Abbott
Laboratories in Chicago in Corporate Planning and Development.   Mr.
Lobdell  worked for the Harbour Group, a St. Louis based  investment
company, from 1979 to 1991 and was appointed President in 1987.   He
served  on  the  Board of Directors of virtually  all  of  Harbour's
portfolio companies acquired during his tenure.

      Alfred Alberts was named a Director of the Company in February
1997.  Mr. Alberts is currently serving on the Board of Directors of
Inflazyme  Pharmaceuticals, Ltd., Vancouver,  and  is  a  scientific
consultant to several major pharmaceutical companies.  He served  as
the Vice President of Biochemistry and Natural Product Discovery  at
Merck  Research Laboratories prior to his retirement in 1995.  Prior
to  joining  Merck, Mr. Alberts was a member of the faculty  of  the
Department of Biochemistry at Washington University, St. Louis.  Mr.
Alberts has co-authored six patents and received several prestigious
awards  including the Thomas Alva Edison Award, the Inventor of  the
Year Award as well as an Honorary Doctor of Science degree from  the
University of Maryland.

      Stewart  Carrell has been a Director of the Company since  May
1994.  He also serves as Chairman of the Board of Directors of Evans
&   Sutherland   Computer  Corporation  and   of   Seattle   Silicon
Corporation.   Between 1984 and 1994, Mr. Carrell was  Chairman  and
Chief Executive Officer of several companies through his association
with the investment banking and venture capital firm of Hambrecht  &
Quist.   Prior  to 1984, Mr. Carrell was employed for  25  years  by
Texas  Instruments in various capacities, the most recent  of  which
was  Executive  Vice President.  Mr. Carrell holds an  undergraduate
degree from Southern Methodist University and a Masters degree  from
Stanford University.

      Dr.  John  P.  McAlister, III has served  as  Chief  Executive
Officer  and  Director since May 1994.  Dr. McAlister  obtained  his
B.S.  in Chemistry from Tarleton State College in 1971 and his Ph.D.
in  Biochemistry  and X-Ray Crystallography from the  University  of
Wisconsin,   Madison,  in  1978.   After  a  two-year  post-doctoral
appointment, Dr. McAlister joined the staff of the Computer  Systems
Laboratory  at Washington University, St. Louis, in 1980,  where  he
served   first   as  Associate  Director  of  the   MMS-X   National
Collaborative  Research Program and then as  Research  Associate  in
Computer  Science.  Dr. McAlister began working for Tripos  in  1982
under  contract  to  supervise software  development  for  molecular
graphics  applications.  In 1984, he joined Tripos  as  Director  of
Software Research and Development.  In 1987, Dr. McAlister was named
Vice  President, Research and Development, and in 1988 was  promoted
to President.

      Gary  Meredith was named a Director of the Company in  January
1996.   He  presently  serves as Senior Vice President  of  Evans  &
Sutherland Computer Corporation ("E&S").  Mr. Meredith has been with
E&S for twenty-one years during which time he held several positions
including  Assistant to the President, VP-Administration, President-
Interactive  Systems  Division, VP-Development  and  Secretary,  and
Chief Financial Officer.  Prior to joining E&S, he was President  of
Interwest General Corporation and Windsor Industries.  Mr.  Meredith
also was Chairman and President of Reid-Meredith, Inc., a company he
founded in 1962.  Mr. Meredith received his B.S. degree from Brigham
Young  University.   In addition to his position  on  the  Board  of
Directors  of  Tripos, Mr. Meredith is a Director  of  Regence  Blue
Cross/Blue Shield of Utah.
                    
     Dr. Ferid Murad was named a Director of the Company in November
1996.   Dr.  Murad  received his M.D. and Ph.D.  from  Case  Western
Reserve  University.   Dr.  Murad is the former  Vice  President  of
Pharmaceutical Research and Development at Abbott Laboratories,  and
formerly, the President and CEO of Molecular Geriatrics Corporation,
a  bio-pharmaceutical  company.  Dr. Murad  has  held  a  number  of
notable  positions  during  his career  including  Chairman  of  the
Department of Medicine at Stanford University, Chief of Medicine  at
Palo Alto Veterans Administration Hospital, and Director of Clinical
Research  at  the  University of Virginia School of  Medicine.   Dr.
Murad was the 1998 co-recipient of the Nobel Prize for Physiology or
Medicine  as  well  as the 1996 recipient of the prestigious  Albert
Lasker  Medical  Research  award and is a  member  of  the  National
Academy of Science.  He is currently Professor and Chairman  of  the
Department  of  Integrative Biology, Pharmacology and Physiology  at
the University of Texas Medical School in Houston.

      There are no family relationships among executive officers  or
directors  of  the Company.  No related party transactions  occurred
between the Company and any of the directors or their affiliates.


Board Meetings and Committees

      During  the fiscal year ended December 31, 1998, the Board  of
Directors of the Company held a total of ten (10) meetings.   During
this  period, a quorum of directors attended or participated in  all
of  (i)  the  meetings  of the Board that were  held  and  (ii)  the
meetings  held  by all committees of the Board of  which  they  were
members.

      The  Company has an Audit Committee, a Compensation Committee,
an  Executive  Committee, and a Technical Review  Committee  of  the
Board  of  Directors.  There is no nominating committee or committee
performing the functions of such committee.

       The  Audit  Committee  meets  with  the  Company's  financial
management  and its independent accountants at various times  during
each  year and reviews internal control conditions, audit plans  and
results,   and  financial  reporting  procedures.   This  Committee,
consisting  of Stewart Carrell, Ralph Lobdell, Alfred Alberts,  Gary
Meredith and Ferid Murad, held two (2) meetings during fiscal 1998.

      The  Compensation Committee reviews and approves the Company's
compensation   arrangements   for   management.    This   Committee,
consisting  of Ralph Lobdell, Alfred Alberts, Stewart Carrell,  Gary
Meredith  and  Ferid  Murad, held three (3) meetings  during  fiscal
1998.

      The  Executive  Committee receives investment  proposals  from
within  and  without  the  Company and decides  whether  they  merit
consideration.  This Committee, consisting of Ralph Lobdell,  Alfred
Alberts,  Stewart Carrell, Gary Meredith and Ferid Murad,  held  two
(2) meetings during fiscal 1998.

      The  Technical  Review  Committee  reviews  and  approves  the
mechanisms  by  which scientific and software development  decisions
are  made  by  the  Company.   This Committee,  consisting  of  John
McAlister,  Alfred Alberts, Ferid Murad  and several key  employees,
did not meet during fiscal 1998.

Director Remuneration

      Non-employee members of the Board, except for Mr. Lobdell, are
each paid an annual retainer of $10,000, and are reimbursed for  all
out-of-pocket costs incurred in connection with their attendance  at
all  Board  meetings and applicable committee meetings.  The  annual
retainer  is  paid quarterly in the form of 50% cash and  50%  stock
valued  at  the  then market rate.  Employee members  of  the  Board
receive no additional compensation for their service on the Board.

     Under the Tripos, Inc. 1994 Director Option Plan, an individual
who first becomes a non-employee member of the Board will receive an
automatic  option  grant for 10,000 shares of the  Company's  Common
Stock  upon commencement of Board service, and each individual  with
six or more months of Board service will receive an automatic option
grant  for  an  additional 2,500 shares on January 1 of  each  year.
Options  issued  under  the Tripos, Inc. 1994 Director  Option  Plan
become  exercisable at a rate of twenty-five percent  (25%)  of  the
shares  under  such option on each anniversary of the grant  of  the
option.  There are currently 240,000 shares reserved for issuance of
options  under  the  1994 Director Option  Plan,  as  amended.   The
exercise  price  for  the options granted under  the  1994  Director
Option Plan is equal to the fair market value of the Common Stock as
of  the last trading day immediately prior to the date the option is
granted.   The  options  have a term of ten  years.   However,  each
option automatically terminates 90 days after the optionee ceases to
be  a  director  of the Company except by reason of  the  optionee's
death, disability, or employment by the Company or a subsidiary, and
terminates within twelve (12) months after the occurrence of one  of
these stated events.

     Dr. Ferid Murad, receives a $1,000 fee for his role as Chairman
of  the Technical Review Committee for every meeting he attends, and
is  reimbursed  for  all  out-of  pocket  costs  incurred  with  his
attendance at such meetings.

      Mr.  Ralph  Lobdell receives an annual retainer of $25,000  as
Chairman of the Board for the Company, in lieu of the $10,000 annual
retainer  received  by  other non-employee  Board  members,  and  is
reimbursed  for all out-of-pocket expenses related to attendance  at
meetings  of the Board of Directors.  Mr. Lobdell's annual  retainer
is  paid  quarterly in the form of 50% cash and 50% stock valued  at
the then market rate.

      No  other compensation is paid to the non-employee members  of
the Board with respect to service on the Board.

Recommendation of the Board of Directors

      The  Board of Directors recommends that the shareholders  vote
FOR the election of each of the above nominees.

                                  
                       OWNERSHIP OF SECURITIES

     The following table sets forth, as of the Record Date, the name
of  each person who owns of record or is known by the Company to own
beneficially more than 5% of the outstanding shares of Common Stock,
the  number of shares owned by all directors, the executive officers
named  in  the  Summary  Compensation Table  (the  "Named  Executive
Officers") and all directors and executive officers as a group,  and
the  percentage of the outstanding shares represented thereby.   The
Company  believes that each of the directors and executive  officers
has  sole  voting  and investment power over such shares  of  Common
Stock.

Holders of More than 5%
                                  Amount and  
                                  Nature of           (1)
Name  and  Address of             Beneficial       Percent of
Beneficial Owner                  Ownership          Class
                                                   
Brown Capital Management          359,700 (2)       11.0%
809 Cathedral Street                   
Baltimore, Maryland 21201

State  of  Wisconsin              303,334 (2)        9.3%
Investment Board                            
121 East Wilson Street
Madison, Wisconsin  53707

Dimensional Fund Advisors, Inc.   205,165 (2)        6.3%
1299 Ocean Avenue                
Santa Monica, California 90401

Casdin Capital Partners LLC       192,700 (3)        5.9%
230 Park Avenue                                    
New York, New York 10169
                                                   

Directors and Named Executive Officers:

                                  Amount and       
                                  Nature of         (1)
Name of Beneficial Owner          Beneficial      Percent
                                  Ownership         of
                                                   Class
                                                   
Ralph S. Lobdell                    52,578         1.6%
Alfred Alberts                      6,415            *
Stewart Carrell                     47,446         1.5%
Gary Meredith                       10,571           *
John P. McAlister III              140,375         4.3%
Ferid Murad                         14,756           *
Martin Bohl                         14,680           *
Richard D. Cramer III               54,371         1.7%
Martin Stuart                       27,635           *
Paul L. Weber                       32,960         1.0%
                                                   
All directors and named                            
executive officers
    as a group (10 persons)        401,787       12.3%

 *   Less than one percent of the outstanding Common Stock.
(1)     Percentage  of  beneficial ownership is calculated  assuming
  3,256,722  shares  of Common Stock were outstanding  on  April  2,
  1999.   This  percentage also includes Common Stock of which  such
  individual or entity has the right to acquire beneficial ownership
  within  sixty days of April 2, 1999, including but not limited  to
  the exercise of an option; however, such Common Stock shall not be
  deemed  outstanding  for the purpose of computing  the  percentage
  owned  by  any  other individual or entity.  Such  calculation  is
  required by Rule 13d-3(d)(1)(i) under the Securities Exchange  Act
  of 1934.
(2)     This  information is based on Schedules 13G filed  with  the
  Securities  and  Exchange Commission (the "SEC").   The  reporting
  entity  attests  that they have sole voting and  investment  power
  over their reported shares of Common Stock.
(3)This  information is based on Schedules 13G filed with  the  SEC.
  The reporting  entity attests  that they  have shared  voting  and
  investment power over their reported shares of Common Stock.

Section  16(a) of the Securities Exchange Act of 1934  requires  the
Company's officers and directors, and persons who own more than  ten
percent  of the Company's Common Stock, to file reports of ownership
and   changes   in  ownership  with  the  Securities  and   Exchange
Commission.    Officers,  directors  and  greater  than  ten-percent
shareholders are required by SEC regulation to furnish  the  Company
with copies of all Section 16(a) forms they file.

Based  on its review of the copies of such forms received by  it,  or
written representations from certain reporting persons that no  year-
end  reports on Forms 5 were required for those persons, the  Company
believes that, during fiscal 1998, all filing requirements applicable
to  its  officers, directors, and greater than ten-percent beneficial
owners were complied with except that Dr. Ferid Murad failed to  file
a  monthly  report of a transaction but he did report the transaction
in his year-end report on Form 5, which was timely filed.

                                  
                                  
                             MANAGEMENT
                                  
Set forth below is certain information with respect to additional
executive officers and key employees of the Company not listed in
"Election of Directors":

         Name           Age       Title

Martin Bohl              56    Vice President, European Operations
Richard D. Cramer, III   57    Vice President, Scientific Activities
Robert C. Glen           45    Vice President, ADS Research US and Asia
Peter Hecht              36    Vice President, European Research Operations
Trevor Heritage          32    Vice President, Software Research and
                                Development
Colleen A. Martin        38    Vice President, Chief Financial Officer, and
                                Secretary
David E. Patterson       47    Senior Fellow
Martin Stuart            42    Vice President, Sales and Marketing
Paul L. Weber            40    Vice President, Software Consulting Services
Mary P. Woodward         53    Vice President, Strategic Development
John D. Yingling         42    Corporate Controller and Treasurer

      Dr. Martin Bohl obtained his training at the Friedrich Shiller
University of Jena in Germany, receiving the Diplom-Chemiker  degree
in  1974 and a Ph.D. in theoretical chemistry in 1979.  After  three
years  of  research and management at the Jenaer Glaswerk  Schott  &
Gen., Dr. Bohl joined the Academy of Sciences, Central Institute  of
Microbiology and Experimental Therapy in Jena.  During an eight-year
period,  Dr.  Bohl's  major  interests  included  structure-activity
relationships  of steroids.  Dr. Bohl joined Tripos in  1989  as  an
Application  and  Sales Support Scientist.  Other positions  he  has
held include: Manager of the Munich Sales Office, European Technical
Manager,  and General Manager for Central and Southern Europe.   Dr.
Bohl  was promoted to Vice President of European Software Operations
in   October   1996.   In  January  1999,  Dr.  Bohl   assumed   the
responsibility  of sales manager for all products  and  services  in
Europe.

      Dr.  Richard  D.  Cramer, III received his  A.B.  degree  from
Harvard  University in Chemistry and Physics in 1963, and his  Ph.D.
in  Physical  Organic Chemistry from the Massachusetts Institute  of
Technology in 1967.  Dr. Cramer worked for Polaroid Corporation from
1967 through 1969.  This was followed by a two year fellowship as  a
senior  member of the computer synthesis group at Harvard University
under direction of Dr. E. J. Corey.  Dr. Cramer joined Smith Kline &
French  Laboratories in 1971.  He was awarded a succession of titles
culminating  in Associate Director and Fellow, Medicinal  Chemistry.
Dr.  Cramer joined Tripos in 1983 as Vice President of New  Products
where  he  formulated  the  techniques  of  Comparative    Molecular
Field    Analysis   (CoMFA),  a   patented   software    technology,
at   Tripos.   Dr.  Cramer  was named Vice President  of  Scientific
Activities  in 1988.  Dr. Cramer also founded and previously  served
on the Board of Directors of STATS, Inc.

      Dr.  Robert C. Glen  received his B.S. in Chemistry  from  the
University  of Paisley, Scotland in 1978 and his Ph.D. in  Chemistry
and  X-ray Crystallography from the University of Stirling in  1982.
Dr.  Glen  was  a  Senior Physical Chemist with  responsibility  for
computer-aided  molecular  design (CAMD) at  the  Wellcome  Research
Laboratories, in London, from 1982 to 1987.  After a short period at
ICI  Pharmaceuticals,  Dr. Glen returned to  Wellcome  as  a  Senior
Research  Scientist  responsible for CAMD, Protein  Crystallography,
measured  physico-chemical  properties  and  Quantitative  Structure
Activity  Relationships.  Dr. Glen has published over 70  scientific
papers  in drug discovery and holds a number of patents on drugs  in
the  clinic,  including Zomig (Zolmitriptan) for  the  treatment  of
migraine.  Dr. Glen joined Tripos in June 1995 as Senior Director of
Science.  In February 1996, Dr. Glen was promoted to Senior Director
of   Collaborative   Discovery  Services  and  to   Vice   President
Collaborative Discovery Services in August 1996.  He was named  Vice
President, ADS Research US and Asia in November 1997.

      Dr.  Peter  Hecht   received a degree in pharmacy from  Vienna
University,  Austria in 1987.  From 1987 to 1990 he  worked  at  the
Sandoz  Research  Institute in Vienna on the design  of  anti-fungal
compounds as part of his Ph.D. thesis, which he completed  in  1990.
From  1990 to 1992 he served as a post-doctoral researcher at Tripos
St.  Louis, funded initially by Sandoz then by the Erwin Schroedinger
scholarship.   From  1992 to 1995 he worked at the  Sandoz  Research
Institute  in  Vienna  as head of the local computational  chemistry
group.    In  1995,  he  joined  Tripos  in  Munich  and  has   been
establishing  the drug discovery efforts of Tripos as  well  as  the
consultancy  service business in Europe.  Dr. Hecht was promoted  to
Vice  President,  European  Research  Operations  and  additionally,
General Manager of Tripos Receptor Research, in November 1997.

      Dr.  Trevor Heritage  received his Ph.D. in Organic  Chemistry
from  University  of Reading, England in 1990.  Dr. Heritage  joined
Shell  Research Ltd. in 1990 as a computational chemist  working  on
the   design  of  agrochemical  products,  catalysts  and  petroleum
additives.   Dr. Heritage joined Tripos in 1994, where he  has  held
scientific  research, marketing, and software development positions.
Dr.   Heritage  has  played  a  leading  role  in  the  design   and
implementation  of  Tripos'  UNITY,  EVA/QSAR,  and  patented  HQSAR
technology.   Dr. Heritage was promoted to Vice President,  Software
Research and Development in April 1998.

      Ms. Colleen A. Martin  received her Bachelor of Science degree
in  Accounting from the University of Missouri, St. Louis,  in  1982
and  has  attended  Northwestern University's J.L. Kellogg  Graduate
School  of  Management Executive Programs.  Ms. Martin, a  Certified
Public  Accountant, worked on the audit staff for KPMG Peat  Marwick
LLP from 1982 through 1984 and worked for Continental Cablevision as
District  Controller  from 1984 through  1989.   Ms.  Martin  joined
Tripos in June 1989 as Controller and was promoted to Vice President
and Chief Financial Officer in April 1995.

       Mr.   David  E.  Patterson   received  his  B.S.  in  Applied
Mathematics  and  Computer Science in 1974  and an M.S.  in  Systems
Science  in  1980  from Washington University  in  St.  Louis.   Mr.
Patterson worked as a Senior Research Scientist with the Center  for
Air  Pollution  Impact and Trend Analysis from  1976  until  joining
Tripos  in  1986.  His positions have included Product  Manager  for
QSAR and Senior Director of New Products prior to being promoted  to
Senior Fellow in March 1996.

      Dr. Martin Stuart  received his Bachelor of Science in Physics
and  Mathematics  from the Council for National Academic  Awards  in
London in 1982.  He was awarded a Ph.D. in the Physics of Thin Films
from the University College of North Wales in 1986.  Dr. Stuart is a
member  of  the  Institute of Physics and is a Chartered  Physicist.
Dr.  Stuart  joined  3M Company in 1974 and held several  scientific
positions,  and  ultimately, Senior Research  Scientist.   His  work
ranged from optimization of photographic development systems to  the
design of highly efficient drug delivery systems.  Dr. Stuart joined
Tripos  in  1987 to support its products in the United  Kingdom  and
Scandinavia.   He was promoted to Manager of Asia Pacific  Sales  in
1993.  Dr. Stuart was promoted to Vice President of the Americas and
Asia  Pacific  Sales  in February 1996.  In November  1997,  he  was
promoted  to Vice President and General Manager, ADS Products.   Dr.
Stuart  was  promoted  to  Vice President, Sales  and  Marketing  in
November 1998.

      Dr. Paul L. Weber  obtained his Bachelor of Science degrees in
Chemistry and Honors Biology from the University of Illinois, Urbana
in  1981.   He  was  awarded  his Ph.D.  in  Biochemistry  from  the
University of Washington, Seattle in 1985.  Prior to joining Tripos,
Dr.  Weber  was  employed as Director of Scientific Applications  at
Hare Research, Inc. where he was involved with business development,
customer  support, sales and program documentation, development  and
debugging.   Dr.  Weber joined Tripos in January  1991  as  the  NMR
Project Manager.  In January 1995, Dr. Weber was promoted to  Senior
Director,  Product  Development  and  in  November  1995   to   Vice
President,  Product  Development. In 1997, Dr. Weber  initiated  the
Software  Consulting Services effort and was named  Vice  President,
Software Consulting Services.

      Ms.  Mary  P.  Woodward  obtained her  B.A.  in  English  from
Creighton  University  in  1967,  her  M.A.  in  English  from   the
University  of  Kansas  in  1969, and  has  taken  courses  in  high
technology,  international marketing and strategic alliance  offered
in  the  Berkeley, Stanford, and Northwestern J.L. Kellogg  Graduate
School  of  Management Executive Programs.  Since joining Tripos  in
1983,  Ms. Woodward has held a series of sales, legal, and marketing
administration positions, and is currently Vice President, Strategic
Development.

      Mr.  John D. Yingling  received his Bachelor of Science degree
in  Accounting from the University of Missouri, St. Louis,  in  1979
and  holds  certificates  as a Certified  Public  Accountant  and  a
Certified  Cash  Manager.  Mr. Yingling worked for Storz  Instrument
Company,  a micro-surgical instrument manufacturer, in a  series  of
accounting  positions  from 1979 to 1983 and for  Clayton  Brokerage
Company from 1983 to 1985.  This was followed by several accounting,
tax  and  treasury positions at Venture Stores, Inc.  from  1985  to
1995.  Mr. Yingling joined Tripos in May 1995 as U.S. Controller and
was promoted to Corporate Controller & Treasurer in January 1999.
                                  
                                  
           EXECUTIVE COMPENSATION AND RELATED INFORMATION
                                  
Summary of Cash and Certain Other Compensation

   The  following table sets forth the compensation  earned  by  the
Named Executive Officers for services rendered in all capacities  to
the Company and its subsidiaries for the fiscal years ended December
31, 1998, December 31, 1997, and December 31, 1996.

                     SUMMARY COMPENSATION TABLE
                                  
                                 Annual             Long-Term        
                              Compensation    Compensation Awards
                                                        Securities       
                                                        Underlying    All Other
 Name & Principal           Salary    Bonus    LTIP      Options    Compensation
     Position       Year    ($) (1)  ($) (2)  Payouts $   # (3)        ($) (4)
                                                                    
John P. McAlister,III
President and Chief 1998    202,083       -        -          -          4,656
Executive Officer   1997    170,833  100,000       -      12,000        10,902
                    1996    150,000       -        -      15,000         4,500
                                                                    
Martin Bohl         1998    101,826   31,625       -       2,000         8,473
Vice President,     1997 #  100,000   67,465       -       5,000        15,972
European Operations
                                                                    
Richard D. Cramer, III
Vice President,     1998    128,750       -        -      10,000            -
Scientific          1997    115,000   38,669       -       5,000         2,588
Activities          1996    115,000       -        -       5,000            -
                                                                    
Martin Stuart       1998    130,894   74,280       -       5,000         6,080
Vice President,     1997 #   89,167   85,222       -      22,500        15,027
Sales & Marketing
                                                                    
Paul L. Weber       1998    122,854    9,916       -       5,000        13,031
Vice President,     1997     99,000   35,000       -       5,000         4,020
Software            1996     94,551       -        -          -          2,837
Consulting
 Services
                                                                    
W. Ward Davidson,III
Former              1998 +   45,859   58,490       -          -          3,797
Vice President,     1997    120,000  101,580       -       5,000        30,757
Sales               1996    120,000   76,881       -          -          8,750

(1)  Includes salary deferred under the Company's 401(k) Plan.
(2)    Bonuses earned were based on an allocation of a discretionary
  bonus pool.  Bonuses for fiscal years 1996, 1997 and 1998 for  Mr.
  Davidson  were  earned  based  on  commissions  payable  upon  the
  Company's  achievement  of  targeted  revenue  levels.   The  1998
  bonuses  paid  to  Messrs.  Bohl,  Stuart  and  Weber  included  a
  commission related to achieving targeted revenue goals.
(3)   The  number of shares underlying option grants include options
  granted to Tripos employees under the 1994 Stock Option Plan.
(4)  "All Other Compensation" includes a matching contribution to the
  Company's 401(k) Plan.  It also includes a car allowance for   Mr.
  Davidson ($1,600), Mr. Stuart ($1,200) and Mr. Bohl ($5,238) and a
  relocation allowance for Mr. Weber ($9,211).
+     Mr.  Davidson's 1998 compensation reflects the period up until
  his resignation from the Company on May 3, 1998.
#     Mr. Stuart and Mr. Bohl became named executive officers of the
  Company during 1997.


Stock Options

   The following table contains information concerning the grant  of
stock options made to the Named Executive Officers in 1998.

                OPTION/SAR GRANTS IN LAST FISCAL YEAR
                                  
                   Individual Grants                       Potential Realizable
                 Number of   % of Total                       Value at Assumed
                 Securities  Options/                         Annual Rates of
                 Underlying  SARs        Exercise             Stock Price
                 Options/    Granted to  Price                Appreciation for
                 SARs        Employees   Per      Expiration  Option Term
      Name       Granted     in Fiscal   Share    Date        5% (3)   10% (3)
                             Year         (2)
John P. McAlister     -         -         -        -             $-       $-
Martin Bohl        2,000(1)    1.3%      $12.375  3/16/08     $15,565  $39,445
Richard D. Cramer 10,000(1)    6.7%      $12.375  3/16/08     $77,826 $197,226
Martin Stuart      5,000(1)    3.4%      $12.375  3/16/08     $38,913  $98,613
Paul L. Weber      5,000(1)    3.4%      $12.375  3/16/08     $38,913  $98,613
                                                                       

(1)     The  options granted under the 1994 Stock Option Plan become
  exercisable  as  to  25%  of  the  option  shares  on  the   first
  anniversary of the grant date and 1/48th per month for three years
  thereafter.  The options have a 10-year term, subject  to  earlier
  termination  in the event of the optionee's cessation  of  service
  with the Company.
(2)     The  exercise price of each option may be paid in  cash,  in
  shares of Common Stock valued at fair market value on the exercise
  date or through a cashless exercise procedure involving a same-day
  sale of the purchased shares.
(3)     The  five percent (5%) and ten percent (10%) assumed  annual
  rates  of compounded stock price appreciation are mandated by  the
  rules  of  the Securities and Exchange Commission.   There  is  no
  assurance provided to any executive officer or any other holder of
  the  Company's securities that the actual stock price appreciation
  over  the  10-year option term will be at the assumed  5%  or  10%
  levels or at any other defined level.

Option Exercises and Holdings

      The  following table provides information with respect to  the
Named  Executive Officers concerning unexercised options held as  of
the end of the 1998 fiscal year.

           AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR
                  AND FISCAL YEAR-END OPTION VALUES
                                  

                                        Number of                 
                Shares                  Securities
               Acquired                  Underlying       Value of Unexercised
                  on     Value     Unexercised Options   in-the-Money Options
    Name       Exercise Realized    at Year-End 1998       at Fiscal Year-End
                                                Un-                     Un-
                   #        $    Exercisable exercisable Exercisable exercisable
John P. McAlister  0       $0      128,626     13,374     $322,971  (1) $7,029
Martin Bohl        0       $0       11,563     10,437       $7,875  (1)     $0
Richard D. Cramer  0       $0       48,788     15,312     $104,317  (1)   $195
Martin Stuart      0       $0       17,397     25,103       $7,875  (1)     $0
Paul L. Weber      0       $0       28,074     11,926      $65,217  (1) $6,033
                                                                       

(1)  Based on the fair market value of Tripos Common shares on
December 31, 1998 ($7.625 per share).
                                  
                REPORT OF THE COMPENSATION COMMITTEE
                                  
      The  following is the Report of the Compensation Committee  of
the   Board   of   Directors  ("the  Committee"),   describing   the
compensation  policies  and rationale applicable  to  the  Company's
executive  officers with respect to the compensation  paid  to  such
executive  officers  for  the year ended  December  31,  1998.   The
Compensation Committee of the Board of Directors is responsible  for
setting  the  general compensation policies of  the  Company,  which
include  specific compensation levels for executive officers,  bonus
pools,  and  the 1994 Tripos Stock Option Plan.  These programs  and
the  Committee's compensation philosophy are designed to attract and
retain key executives by providing appropriate incentives linked  to
Company  performance. The Committee is composed of all  non-employee
Directors.

Compensation Philosophy

      The  Compensation Committee evaluates the performance  of  the
Chief  Executive Officer and other officers of Tripos annually based
upon  financial and non-financial performance goals which contribute
to the profitability of the Company.  The Compensation Committee has
approved  compensation policies that seek to enhance the linkage  of
compensation  to Company objectives and overall company performance.
The  executive  officers' compensation package is comprised  of  (i)
base  salary, (ii) annual incentive opportunity tied to  achievement
of  Operating Income and other goals, and (iii) long-term incentives
established  to align management with shareholders, in the  form  of
stock   options.  The  Chief  Executive  Officer  recommends  annual
increases for other executives for review and approval by the Board.

                 Base Salaries --   Individual salary increases  are
          likely to be based on a variety of factors including,  but
          not  limited to: competitive salary levels, individual job
          responsibilities,  results versus target  objectives,  and
          Company financial performance.

               Annual  Incentives -- Effective for fiscal  1995  and
          later  years,  the  Company's officers  were  eligible  to
          participate  in  an  annual incentive  compensation  plan.
          Annual  incentive targets are set as a percent  of  salary
          for  each  officer based on attainment of financial  goals
          including  Operating  Income  and  individual  performance
          goals.   Weighting  of goals varies by participant.   Over
          120%  of the Operating Income goal was achieved in  fiscal
          1996,  therefore a payout related to financial  goals  was
          made in early 1997.  No payout was made in 1996 for fiscal
          1995 nor in 1998 for fiscal 1997 or in 1999 for 1998.

                Long-term Incentives -- The Company has adopted  the
          1994  Tripos Stock Option Plan to attract and  retain  the
          best  available  personnel  for positions  of  substantial
          responsibility,   to  provide  additional   incentive   to
          employees,  and  to promote the success of  the  Company's
          business.  Awards under the 1994 Tripos Stock Option  Plan
          are  designed  to give the recipient a significant  equity
          stake  in  the  Company and thereby  closely  align  their
          interests  with those of the Company's shareholders.   The
          Committee  has  established certain general guidelines  in
          making  option grants to executive officers in an  attempt
          to  target a fixed number of unvested option shares  based
          upon the individual's position with the Company and his or
          her existing holdings of unvested options.  The number  of
          shares  granted to each executive officer in fiscal  years
          1998,  1997 and 1996 was based upon the officer's  tenure,
          level  of  responsibility, and relative  position  in  the
          Company.   However, the Committee does not adhere strictly
          to these guidelines and will occasionally vary the size of
          the  option  grant  made  to  each  executive  officer  as
          circumstances warrant.

      The  Internal  Revenue  Code, and the  regulations  promulgated
thereunder,  limit  the tax deduction the Company may  recognize  for
compensation  paid  to its executive officers whose  compensation  is
listed in this Proxy Statement, to $1.0 million per person, per year.
This  deduction  limit does not apply to compensation  that  complies
with   applicable  provisions  of  such  regulations.   Because   the
Committee did not expect the compensation to be paid to such  persons
to exceed $1.0 million per person in 1998, the Committee did not take
any action prior to or during 1998 which would have been required  to
comply  with  the  aforementioned regulations so that  the  deduction
limit  would not apply.  The Committee will continue to evaluate  the
other components of the Company's executive compensation program  and
will  take the necessary actions with respect to such regulations  if
it  is deemed appropriate to do so with respect to compensation to be
paid to executive officers in future years.


Chief Executive Officer Compensation

     The  Chairman  and other members of the Compensation  Committee
meet  semi-annually  with  Dr. McAlister  to  discuss  his  personal
performance during the fiscal year.  The Committee's objective is to
have  Dr. McAlister's base salary keep pace with the salaries  being
paid  to  similarly situated CEOs in the software and  biotechnology
industries,  and reflect individual performance and  achievement  of
Tripos  corporate  goals.  Dr. McAlister's base salary  is  reviewed
annually  by  the Compensation Committee based on these  discussions
and other criteria mentioned above.

      Notwithstanding anything to the contrary set forth in  any  of
the  Company's previous filing under the Securities Exchange Act  of
1934  that  might incorporate future filings, including  this  Proxy
Statement,  in  whole  or  in part, the  foregoing  report  and  the
Performance  Graph  which  follows  shall  not  be  deemed   to   be
incorporated by reference into any such filing.

          Compensation Committee
          Mr. Ralph S. Lobdell, Chairman
          Mr. Stewart Carrell
          Mr. Gary Meredith
          Dr. Ferid Murad
          Mr. Alfred Alberts


                  COMPARISON OF SHAREHOLDER RETURN
                                  
        Indexed Comparison of Total Return since Distribution
        Total Return Index for the NASDAQ National Market and
          Total Return for NASDAQ Pharmaceutical Companies
                                  
                   <Graph of the following table>


                  6/1/94  12/31/94  12/31/95  12/31/96  12/31/97  12/31/98
NASDAQ            100.00    103.13    145.86    179.37    220.06    309.34
Pharmaceuticals   100.00     97.46    178.76    179.31    185.15    237.00
Tripos, Inc.      100.00     86.36    154.55    213.64    265.91    138.64
                                  

Note:      Assumes $100 invested on 6/1/94 in the Company, the total
return  index  for the NASDAQ National Market and the  total  return
index for NASDAQ Pharmaceutical Companies.  Assumes reinvestment  of
dividends on a daily basis.

      The  graph covers the period from June 1, 1994, the  date  the
Company's distribution of Common Stock to holders of record  of  the
Common  Stock  of  E&S  commenced, through  the  fiscal  year  ended
December 31, 1998.  The graph assumes that $100 was invested on June
1, 1994 in the Company's Common Stock and in each index and that all
dividends were reinvested.  No cash dividends have been declared  on
the  Company's Common Stock.  Shareholder returns over the indicated
period  should  not  be considered indicative of future  shareholder
returns.


                            ANNUAL REPORT
                                  
      A copy of the Annual Report of the Company for the fiscal year
ended December 31, 1998 has been mailed concurrently with this Proxy
Statement to all shareholders entitled to notice of and to  vote  at
the  Annual  Meeting. The Company filed a Form 10-K  with  the  SEC.
Shareholders may obtain a copy of the Form 10-K without  charge,  by
writing  to  Colleen Martin/Corporate Secretary,  at  the  Company's
executive  offices  at 1699 South Hanley Road, St.  Louis,  Missouri
63144.

             SELECTION OF INDEPENDENT PUBLIC ACCOUNTANTS
                                  
       Ernst  & Young LLP, independent certified public accountants,
has been selected by the Board of Directors as the firm to audit the
accounts  and to report on the financial statements of  the  Company
for the current fiscal year ending December 31, 1999.  Neither Ernst
&  Young  LLP,  nor  any of its members has any financial  interest,
direct  or indirect, in the Company, nor has Ernst & Young LLP,  nor
any of its members ever been connected with the Company as promoter,
underwriter, voting trustee, director, officer or employee.   It  is
anticipated  that a representative of Ernst & Young LLP will  attend
the  meeting  and  shall  be  available to  respond  to  appropriate
questions.  It is not anticipated that the representative from Ernst
& Young LLP will make any statement or presentation.



                            OTHER MATTERS
                                  
      The  Board  of  Directors does not know of any matters  to  be
presented  at this Annual Meeting other than those set forth  herein
and in the Notice accompanying this Proxy Statement.

                                   TRIPOS, INC.


                                   /s/ Colleen A. Martin
                                   Colleen A. Martin
                                   Corporate Secretary

                                   April 9, 1999
                                   St. Louis, Missouri



PROXY CARD




                            Tripos, Inc.
                                  
     THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS
                                  
                                                  April 9, 1999
Dear Shareholder:

     The  undersigned hereby appoints Colleen  A. Martin and John  D.
Yingling  as  proxies,  each  with  full  power  to  appoint  her/his
substitute,  and  hereby authorizes them to vote all  the  shares  of
Common Stock of Tripos, Inc. held of record by the undersigned at the
annual  meeting of shareholders to be held on May 11, 1999,  at  1:00
p.m.,  local  time,  at  the World Trade Center  St.  Louis,  121  S.
Meramec,  10th Floor, Clayton, Missouri, 63105, or at any adjournment
thereof.:  (1) as hereinafter specified upon the proposals listed  on
the reverse and as more particularly described in the Company's proxy
statement, receipt of which is hereby acknowledged; and (2) in  their
discretion  upon such other matters as may properly come  before  the
Annual Meeting of Shareholders.

     PLEASE DETACH AND MARK THE PROXY, SIGN IT ON THE REVERSE SIDE,
AND RETURN IT IN THE ENVELOPE PROVIDED BEFORE THE BEFORE THE MEETING








- ------------------------------------------------------------------------------
                      (Detach Proxy Form Here)

   A VOTE FOR THE FOLLOWING PROPOSALS IS RECOMMENDED BY THE BOARD.

1.   Election of Directors

FOR  O   all nominees listed below        WITHHOLD AUTHORITY  O
(except as marked to the contrary below)  to vote for all nominees listed below

(INSTRUCTION: To withhold authority to vote for any individual nominee,
              strike a line through the nominee's name in the list below)
                                  
Ralph Lobdell,   Alfred Alberts,   Stewart Carrell,  
     John McAlister,   Gary Meredith,   Ferid Murad
                                  
2.   In their discretion, the proxies are authorized to vote on such
  other business as may properly come before this meeting.

This proxy, when properly executed, will be voted in the manner directed
herein by the undersigned shareholder.  IF NO DIRECTION IS MADE, THIS
PROXY WILL BE VOTED  FOR  PROPOSAL  1.
                                        
                                        Dated: ________________________,
                                        1999
                                        
                                        
                                        ________________________________
                                             Signature *
                                        
                                        ________________________________
                                             Signature, if held jointly *
                                        *Please sign exactly as name
                                        appears on this form.  When signing 
                                        as attorney, executor,
                                        administrator, trustee, or
                                        guardian, please give full title
                                        as such.  If a corporation,
                                        please sign in full corporate
                                        name by President or other
                                        authorized officer.  If a
                                        partnership, please sign in
                                        partnership name by authorized person.

 PLEASE MARK, SIGN, DATE AND RETURN THIS PROXY PRIOR TO THE MEETING.





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