NORTHFIELD LABORATORIES INC /DE/
PRRN14A, 2000-09-25
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                  SCHEDULE 14A
                                 (RULE 14a-101)
                     INFORMATION REQUIRED IN PROXY STATEMENT

                            SCHEDULE 14A INFORMATION
           PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES
                              EXCHANGE ACT OF 1934


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--------------------------------------------------------------------------------
                          NORTHFIELD LABORATORIES INC.
                (Name of Registrant as Specified in Its Charter)

                              C. ROBERT COATES and
                            MANAGEMENT INSIGHTS, INC.
--------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

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<PAGE>





                     PRELIMINARY COPY, SUBJECT TO COMPLETION
                     DEFINITIVE COPY INTENDED TO BE RELEASED
                    TO SECURITY HOLDERS ON SEPTEMBER ___, 2000
        PROXY STATEMENT OF C. ROBERT COATES AND MANAGEMENT INSIGHTS, INC.
                               IN CONNECTION WITH
                      A STOCKHOLDER SOLICITATION REGARDING
            THE ELECTION OF DIRECTORS OF NORTHFIELD LABORATORIES INC.

                                                             September ___, 2000

                  C. Robert Coates and Management  Insights,  Inc.  furnish this
Proxy  Statement in connection  with the  solicitation of proxies for use at the
Annual Meeting (the "Annual Meeting") of stockholders of Northfield Laboratories
Inc.  ("Northfield"  or the  "Company")  to be held at 9:00 a.m.  local  time on
October 12, 2000, at Northfield's  corporate headquarters in Evanston, IL, or at
any postponement or  rescheduling.  Copies of the Proxy Statement and proxy card
are being mailed by Mr. Coates and Management Insights,  Inc. to stockholders on
or about  September ___, 2000.  The mailing  address of the Company's  principal
executive offices is: Northfield  Laboratories Inc., 1560 Sherman Avenue,  Suite
1000, Evanston, IL 60201-4800.


Dear Fellow Northfield Stockholder:

C. Robert Coates and Management  Insights,  Inc. are soliciting  your proxies to
elect its nominees to the Board of Directors of Northfield  Laboratories Inc. We
ask for your support because we are concerned about the future of the investment
of  Northfield  stockholders  and the  capability  of the current  directors and
management to make that investment prosper.


                  REASONS FOR ELECTING THE NOMINEES

                  Despite   the  longest   bull  market  in  American   history,
Northfield  stockholders  over the last five years  actually lost money on their
investment.  Northfield's  own proxy admits that, over the 5 year period between
May 31, 1995 and May 31,  2000,  $100  invested in the NASDAQ Stock Market Index
would be worth  $402.10  today and $100  invested  in the NASDAQ  Pharmaceutical
Index would be worth $416.10. That same $100 invested in the stock of Northfield
is now worth only $80.90.


                  Now the Northfield Board of Directors, not wanting to face its
own  stockholders,  is denying you the right to  question  them in person at the
upcoming Annual Meeting and hold them accountable.  In a recent SEC filing, they
announced  that no questions  concerning  the  Company's  progress and prospects
would be allowed at the Annual  Meeting!  You must submit any questions you have
seven days in advance and any answers they choose to give will only be broadcast
over the Internet or the  telephone.  YOUR  DIRECTORS AND THE  MANAGEMENT  WHOSE
SALARIES YOU PAY WON'T EVEN ADDRESS YOU FACE TO FACE.


        NOW THAT SAME GROUP OF DIRECTORS HAS SENT YOU A WHITE PROXY CARD
          ASKING YOU TO RE-ELECT THEM FOR ANOTHER YEAR OF FRUSTRATION.

We have an alternate proposal for you to consider.

Fundamental  changes  in the way the  Company  conducts  its  business  are long
overdue.  We believe that any changes in the Company's policies will require the
participation  of new  directors  who  are  more  committed  to  maximizing  the
Company's value for all stockholders.

To this  end,  we  propose  to ask you to vote  for C.  Robert  Coates,  Bert R.
Williams III, Jerry L. Ruyan, and Christopher S. Coates to serve on Northfield's
Board of Directors.

These  nominees  for  the  board  of  directors  offer  the  fresh  perspective,
experience and judgment that Northfield  stockholders  need to enhance the value
of their  investment.  They are fully  committed to  implementing  the corporate
governance  principles  and practices  that are  fundamental to the success of a
publicly held firm. When individuals - be they doctors, coaches, teachers or any
other kind of American  worker -fail in the performance of their duties they are
first held accountable and then if necessary removed or required to leave.


<PAGE>


THAT TIME HAS ARRIVED FOR THIS BOARD.

If elected, our nominees will immediately  institute a program of accountability
on the part of the company's Chief Executive  Officer AND Board of Directors and
establish the following benchmarks to evaluate their performance.  These will be
communicated on a regular basis to investors:

     o    RETURN ON INVESTMENT AND MARKET  CAPITALIZATION.  ROI is a fundamental
          measurement  of  a  company's  performance.  Hand-in-glove  with  this
          measurement is a company's  market  capitalization.  Questions such as
          "What is the company's market capitalization compared to competitors?"
          and "How has its share  price  performed  over the last  three to five
          years?"  should be  answered.  These are not invasive  questions,  nor
          should  all their  answers  be  proprietary.  Rather,  they  represent
          need-to-know data, a common denominator for all investors.

     o    LEADERSHIP OPENNESS AND INTEGRITY.  The Chief Executive Officer should
          be forthright  and make a good faith effort to accurately  present the
          company to its  stakeholders,  including the  company's  stockholders,
          employees,   current  and  potential  customers,   suppliers  and  the
          surrounding  community in which it does business.  Examples  abound in
          which a  company's  leadership  has been  less  than  candid  with its
          stakeholders,  has disseminated inaccurate  information,  or has hyped
          the  stock  for  artificial  gain.  We  stand  solidly  against  these
          practices.

     o    COMMUNICATION.   What  is  the   company's   level  and   quality   of
          communication?  Does it respond to inquiries  from  stockholders,  the
          media,  and  prospective  customers?  The best  companies  communicate
          frequently  and fully  through  press  releases,  analyst and investor
          conferences,  meetings  with the media and public  speaking.  The
          content of their communication  encompasses  everything from cash flow
          and R&D  performance  to product  development  reports  and  personnel
          changes.  Again, we believe it is the leadership's  responsibility  to
          get in front of those who have a stake in the  company's  welfare  and
          talk about how it plans to make good on their investment.

     o    INSTITUTIONAL  INVESTORS.  Institutional  investors are often key to a
          company's  success.  It's  only  fair  to  ask a  company  how  it has
          cultivated  and  collaborated  with  this  influential   group,  whose
          decision-making power over huge sums of money can go a long way toward
          helping a company reach its goals.  How many  institutional  investors
          are behind the company? Who are they and whom do they represent?  Most
          importantly,  what are they saying about the company? Along with stock
          market analysts,  their  recommendations  carry a tremendous amount of
          weight.

     o    STAFF TALENT.  Investors deserve to know that the leadership is hiring
          top-notch  people,  and that these  people are  filling  jobs that are
          vital to the company's welfare.  For example,  in a company devoted to
          research and development,  a vice-president  of regulatory  affairs is
          critical.  In the biomedical  industry,  experience and a proven track
          record  of  working  with  the Food & Drug  Administration  is a must.
          Further,  every  company  needs a key  executive in charge of business
          development.  Experienced  in marketing  and the building of long-term
          relationships,  this individual  should target potential  customers in
          the military,  health care and disaster  support  agencies such as the
          American Red Cross.

     o    ALLIANCES.  Finally, no company does business in a vacuum. To assess a
          company's performance, it is important to understand the alliances and
          partnerships that it has created to help its product succeed.  This is
          especially true when a product is in the development  stage,  when the
          company does not yet have any other demonstrably  successful  product.
          Stockholders  want to know  whom the  manufacturer  will be,  who will
          distribute it, where the product will be available and how its arrival
          to market will be  communicated.  Again, the disclosure of proprietary
          information  is not  called  for.  An  explanation  of plans to create
          widespread use of the product is.

<PAGE>

MEETINGS ANC COMMUNICATIONS WITH NORTHFIELD MANAGEMENT

During 1998, C. Robert Coates contacted Richard DeWoskin by phone several times.

On about June 1998, he mentioned his recent purchase of a significant  number of
shares and his strong interest in Polyheme.  He also discussed with Mr. DeWoskin
various  topics  that had  been  mentioned  in the  following  Northfield  press
releases:

Northfield Laboratories Enters Home Stretch for Blood Substitute Product, May 6,
1997 PRNewswire. Source: Northfield Laboratories, Inc.

Northfield  Laboratories  to Start  European  Trials  of Blood  Substitute  with
Pharmacia  &  Upjohn  AB,  May  12,   1998.   PRNewswire.   Source:   Northfield
Laboratories, Inc.

Mr.  Coates grew  increasingly  concerned  about  Northfield's  progress and its
direction  as  Northfield's  stock price  declined  from $18.125 in July 1998 to
$9.125 in  October  1998.  His staff  conducted  market  research  and talked to
several experts on blood substitutes and to several doctors at Dallas hospitals.
In several  calls and letters to Mr.  DeWoskin in November and December of 1998,
Mr. Coates offered to share this research with Northfield and Mr. DeWoskin at no
cost.

Mr. DeWoskin declined to discuss the company with Mr. Coates or to meet with Mr.
Coates.

Here are excerpts  from a letter  Management  Insights  sent to Mr.  DeWoskin on
December 1, 1998 by a vice president of Management Insights.

Dear Richard:

It was a pleasure  meeting  you and Steven  Gould at the Blood  Substitutes  and
Oxygen Therapeutics  Conference last week.  Northfield  Laboratories  clearly is
succeeding in the area of research and  development  and should be commended for
its efforts towards bringing PolyHeme to market.

At the same  time,  it is  necessary  for  Northfield  to succeed in the area of
maximizing  shareholder  value,  rewarding  investors  who have  believed in the
Northfield vision.  Without them, the research and development efforts could not
exist. We are not alone in this view as  demonstrated  by other  shareholders at
the Annual Meeting.

For example,  an immediate area where we believe  Northfield  could redirect its
current  effort  is in the  area  of  corporate  communications.  As  Northfield
transitions from a sole focus on R&D to production,  sales and marketing,  it is
imperative  to  deliver a  continuous  flow of press  releases  and  shareholder
communication.

Management Insights believes that at least two substantive press releases should
be provided to the public prior to yearend.  In addition,  the first in a series
of continuous corporate  communiques should begin the first week of January 1999
outlining  and  updating  strategic  direction.  In the  absence of  traditional
financial  and  managerial  measurements  such as return on equity and  earnings
growth, the quality and quantity of positive  information made public becomes an
important yardstick.


<PAGE>


Management  Insights has  attempted  to meet with you on two previous  occasions
with the intention of passing  along our analysis and insight,  however you have
declined meeting in both instances.  For this reason,  we will begin copying the
Directors on all correspondence.


Please  recognize  that our  investment  of 675,000  shares does not represent a
casual  investment.  While it is  certainly  our right to ask for and obtain the
Northfield  shareholder  list,  we are not  doing so at this  time,  as we would
rather work with  management  in an effort to increase  shareholder  value.  Our
offer to meet with you and share our insights remains open. At the same time, we
will  monitor  the  increase  in   Northfield   press   releases  and  corporate
communications  through yearend as a measure of management's  increasing efforts
to improve shareholder wealth.



Mr. DeWoskin wrote back on December 16, 1998. Here are excerpts from his letter:



While I agree with you that Northfield's current stock price does not accurately
reflect  the  Company's  true  long-term  value,  the  Board  of  Directors  and
management  of  Northfield  believe it is not possible at this time to implement
the  measures  suggested in your  letter.  The process of  obtaining  regulatory
approval for PolyHeme in the United  States is at a critical  stage.  Northfield
has concluded that extensive public  communication  regarding its regulatory and
business  strategies  is not  advisable  and that such actions  could in fact be
detrimental to Northfield's efforts to pursue regulatory approval of PolyHeme.



We are also mindful of the possibility that corporate  communications  regarding
the timing of regulatory  approvals and other matters  outside of the control of
the  Company  could be  misperceived  by our  public  shareholders.  Like  other
responsible companies in the industry, Northfield believes it is unfair to raise
shareholder  expectations  regarding  these matters prior to the  achievement of
objective milestones.



Given the foregoing situation, I do not believe it would be productive for us to
meet to  discuss  the  suggestions  raised  in your  recent  letter.  Northfield
appreciates your input and hopes you will continue to support our efforts.



On October 14, 1999,  Mr. Coates sent a letter to Mr.  DeWoskin  requesting  the
opportunity  to review the stocklist and saying that he might  communicate  with
stockholders.  He also said he looked  forward to the annual  meeting on October
28, 1999 and was interested in learning from the meeting  whether  enrollment in
the  expanded  third  stage  trials (600 plus  patients)  was  completed  by the
beginning of the third quarter of 1999 as management had  predicted.  Mr. Coates
also expressed a hope that Mr. DeWoskin would discuss the status of their effort
to enlist a strategic marketing partner.



To Mr.  Coates'  knowledge,  Mr.  DeWoskin did not respond to this letter in any
way.


<PAGE>


During  November and  December,  1999,  Mr.  Coates sent several  letters to Mr.
DeWoskin  asking  to  discuss  the  possibility  of his  joining  the  Board  of
Northfield.  He stated  that he would  prefer  to join the  board by  invitation
rather than through a proxy contest.


To Mr. Coates' knowledge, Mr. DeWoskin did not respond to those letters.

In his letter of December 16, 1999, Mr. Coates said the following:

"I  beneficially  own 652,000 shares of  Northfield's  common stock. I have been
concerned  with  the  direction  of the  company.  I  believe  that my  business
experience may help increase Northfield's shareholder value.

I am  considering  whether to seek  election as a director of  Northfield at its
2000  annual  meeting,  either  alone  or with  other  candidates  who may  have
concerns.  I believe that,  as a director,  I would be able to identify and help
implement meaningful steps to improve the company for all shareholders.

I am  forwarding  this letter to you as an  invitation  to discuss these matters
further.  I hope we have the opportunity to do so in the next few weeks.  Please
contact me at (972) 755-2006."



To our knowledge,  Mr. DeWoskin did not reply to this letter.  So Mr. Coates had
an attorney send a letter on February 28, 2000, asking for a response.



On March 13, 2000, Mr. DeWoskin replied to our attorneys letter as follows:



"With respect to board  membership,  I appreciate your interest.  But, the board
sees no current need to expand its membership. We have, on occasion,  considered
additions to the board.  These were  individuals  with either FDA or health care
backgrounds of specific value to the board at the time of consideration. As your
background doesn't seem to include credentials of this sort, it is unlikely that
the board would favorably act on your expression of interest."


On June 22, 2000,  convinced that there was no other way to get Mr.  DeWoskin to
provide  Northfield's  shareholders with more information about the company, Mr.
Coates issued a press release and mailed a letter to shareholders dated June 19,
2000.  More  than six  hundred  shareholders  responded  to Mr.  Coates'  letter
expressing support for his efforts.


On July  24,  2000 Mr.  C.  Robert  Coates  met with  Northfield  Labs'  CEO and
President,  Mr. Richard  DeWoskin and Dr. Steven Gould,  to discuss our June 19,
2000 letter to the company's stockholders and share the feedback we had received
from many  stockholders  supporting  our actions.  By mutual  consent we did not
discuss any information about Northfield Labs that is not publicly available.

In that meeting, Mr. Coates discussed:

    -- our belief that PolyHeme represented an incredible scientific
       achievement.
    -- his background, including his MBA and PhD in Finance, Economics and
       Accounting  from the University of Chicago,  his ownership and management
       for the last twenty years of a very successful  consulting  company,  and
       his  extensive  experience  in the  valuation  of  companies -- including
       having served as an expert witness in that area.
    -- a comparison of Northfield's market value with those of its peers and
       his reasons for expecting a higher market value if Mr. DeWoskin followed
       standard business practices.  These include adding staff in the marketing
       and investor  relations areas and  communicating  with  securities
       analysts, shareholders, the medical community and the general public.
    -- his concerns that Northfield was falling behind several of its
       competitors.

      See "Stock Value contained in August 31, 2000 Press Release."


Mr. Coates believed that he was going to receive a response from Mr. DeWoskin to
the issues  raised by Mr.  Coates at that  meeting.  When he did not, Mr. Coates
issued his own press release on August 2, 2000 confirming the meeting.

August 10,  2000.  Mr.  Coates  submitted  a detailed  package  nominating  four
directors to the Board of Directors.



On August 14, 2000,  Northfield replied that we may have failed to satisfy their
nomination requirements.



August 15, 2000, we responded to the Northfield  letter by verifying  additional
information about our nominees.



On August 18, 2000,  Northfield  sent a letter saying they would not include the
proposed nominees in the list of directors recommended by the Northfield board.


<PAGE>


August 31, 2000,  Mr. Coates issues a press release  announcing  the filing of a
slate of four directors and distributed a second letter to shareholders.


September 13, 2000, Mr. Coates sent a letter to Mr. Gould  suggesting  that they
get together.



Mr.  Coates  called Mr.  Bruce  Chelberg's  office  several  times in August and
September,  2000 and asked Mr.  Chelberg's  assistant  if he would meet with Mr.
Coates.  Mr.  Chelberg  was in  meetings  and was  unavailable  to meet with Mr.
Coates.



September 18, 2000,  Northfield's attorney sent Mr. Coates a letter stating that
in response to Mr. Coates' letter,  Northfield's  senior  management  would meet
again with Mr.  Coates if Mr.  Coates would  provide an agenda or summary of the
matters  he  would  like to  discuss  at the  meeting.  Mr.  Coates  has not yet
responded to this letter.



STOCK VALUE CONTAINED IN AUGUST 31, 2000 PRESS RELEASE

This Press Release  refers to Mr. Coates'  belief that  Northfield  Lab's common
stock could have a value of thirty-five  dollars ($35.00) or more. His belief is
based on a review of the stock prices of a comparable  company,  Biopure  Corp.,
using the average of the closing stock prices  ($20.21) for all the days in July
2000  immediately  preceding  the  meeting  scheduled  between  Mr.  Coates  and
Northfield  Labs on July 24, 2000,  and dividing that market value by the number
of Northfield shares that were issued and outstanding at that time.  Biopure was
chosen as a comparable  company by Mr. Coates because it has a similar competing
product in the same stage of FDA  development and both companies are one product
companies. Biopure's market value may not be an accurate reflection of the value
of Northfield Lab's common stock. Even if all of our nominees are elected to the
Board,  there can be no  guarantee  that any  actions  they take will  result in
Northfield's Common Stock reaching the value discussed in the press release.


ITEM 1: ELECTION OF DIRECTORS

We believe that Mr. Robert Coates, Mr. Williams,  Mr. Ruyan, and Mr. Christopher
Coates will be the type of  independent,  effective  directors  that  Northfield
needs to protect stockholder  interests and increase  stockholder value. None of
these directors  works for a company that is a direct or indirect  competitor to
Northfield  Labs.  Each of the nominees has  consented to serve as a director if
elected.


Management Insights is primarily a diversified  management  consulting firm with
limited venture  capital  investment  operations.  It has been in business since
1980 and is located primarily in Dallas,  Texas. It specifically advises Fortune
1000 companies in obtaining state and federal tax credits. It has a list of over
50 Fortune 1000 clients. It has 65 employees, many of whom are CPAs and MBAs. It
recently started a recruiting company located in Chicago.



Management  Insights  does not engage in any  investment  activities  other that
those related to the  investments of its own money and the personal  investments
of Mr.  Coates and his  family.  Management  Insights  has  reviewed a number of
possible  venture capital  investments  during the past several years. So far it
has invested in Artbyte,  a magazine,  and in an internal  company venture named
Revhire, a recruiting company.



                                    NOMINEES

C. ROBERT COATES
Age: 55

For the past  twenty  years,  Mr.  Coates  has been Chief  Executive  Officer of
Management Insights, Inc., a diversified management consulting, venture capital,
and investment firm with offices in Lake Forest, IL, Chicago, IL and Dallas, TX.
He maintains homes both in Lake Forest and Dallas.  Mr. Coates earned a Bachelor
of Arts Degree in Economics  with  Distinction  from the University of Virginia,
MBA in Finance from the  University of Chicago and Ph.D.  in Finance,  Economics
and Accounting from the University of Chicago. Mr. Coates served on the Board of
Directors of Inprise Corporation,  a publicly traded company,  from June 1999 to
February 2000. He was not a member of that Board's compensation committee.


<PAGE>


BERT R. WILLIAMS III
Age: 43

Since November 1993,  Bert R. Williams III has been President of Immuno Concepts
N.A.  Ltd.,  a  leading  manufacturer  and  worldwide   distributor  of  medical
diagnostic kits. He is responsible for production,  marketing, technical support
and operations.  He implemented the program that achieved ISO 9001 certification
at Immuno Concepts.

Mr.  Williams has also served as Director of Marketing at Immuno  Concepts since
1985. In that role, he has been responsible for strategic marketing  development
and direction, nationally and internationally.  He expanded international market
penetration from four countries to over sixty. His duties include responsibility
for full-scope marketing, product pricing, campaign development, sales training,
advertising,   collateral   materials  design  and  production,   and  technical
workshops.

Mr. Williams holds a Bachelor of Science degree from Wayne State  University and
an MBA from Marquette University. He also serves as a Director of the Intestinal
Health  Institute,  a  Dallas-based  non-profit  organization,  and has  been an
Adjunct  Professor at the  University of Dallas'  Graduate  School of Management
since 1996. Mr.  Williams is co-patent  holder of patent  #5490830  covering the
innovative design of a biohazard centrifuge.

JERRY L. RUYAN
Age: 54

Jerry L. Ruyan has been Chairman and Chief Executive  Officer of publicly traded
Hemagen  Diagnostics,  Inc.  since  October  1999.  Prior to that, he co-founded
Redwood  Holdings,  Inc., a privately  held venture  capital firm. He co-founded
Meridian  Diagnostics,  Inc., a public  company that  develops  diagnostic  test
products  for the global  medical  industry,  in 1977 and served as its CEO from
1990 through  1992.  He served as a Director of Meridian from March 1977 to July
1999,  when he became  part of a  consent  solicitation  to change  the board of
Hemagen  Diagnostics,  Inc. He has served on the board of  Meritage  Hospitality
Group,  Inc., a publicly  traded  company,  since October 1996. He served on the
board of PopMail.com  Inc, a publicly traded company,  from October 1998 through
April 2000. He has not served on the Compensation Committee of any boards.

He also serves on the boards for Schonstedt Instrument Company and The Last Best
Place  Catalog  Company,  both private  companies,  and is a Trustee for Ashland
University.  Mr. Ruyan earned a B.S.  degree in Biology from Ashland  University
and a Master's Degree in Microbiology from Ohio State University.

CHRISTOPHER S. COATES
Age: 46

Since May 1993  Christopher  S.  Coates has been  President  and CEO of Ahlstrom
Technical  Specialties  LLC,  a  $32  million,   120-employee   manufacturer  of
laboratory  and process  filtration  products used for blood and  pharmaceutical
purification  techniques.   His  responsibilities  include  strategic  planning,
management  of R&D,  production,  and sales  functions,  budgeting and financial
management, and identification and negotiation of acquisitions.

From 1991 to 1993,  Mr. Coates served as the company's  Vice-President  of Sales
and Marketing in the scientific,  industrial,  and non-woven sectors. His duties
included pricing strategy, key account development,  managing inside and outside
sales professionals,  and development of forecasts and long term planning. Prior
to that he was the Director of Marketing for five years,  launching new products
and creating an international distribution network.

Mr. Coates  previously  served in several sales and marketing  capacities in the
analytical, healthcare, and bioscience markets. He holds a B.A. in Chemistry and
Business  from   Shippensburg   University   and  has  completed  the  Executive
Development Program at the INSEAD in Paris, France.



<PAGE>

                            SHARES OWNED BY NOMINEES
The table  below  shows the  amount of  Northfield's  outstanding  common  stock
beneficially owned by the our nominees.




                                            AMOUNT AND NATURE           PERCENT
                                            OF BENEFICIAL               OF
NAME AND ADDRESS                            OWNERSHIP                   CLASS

================================================================================
 C. Robert Coates (1)(6)                    647,550       (2)           4.5%



Bert R. Williams III (3)                    0                          --




Jerry L. Ruyan (4)                          0                          --






Christopher S. Coates (5) (6)               0                          --




(1)  Mr. Robert Coates' main business address is: 14755 Preston Road, Suite 525,
     Dallas TX 75240.

(2)  1,000 shares are held by Mr. Robert Coates in his own name;  357,800 shares
     are personally held in street name,  282,000 shares are held in street name
     by  Management  Insights,  Inc. and 1,750 shares are held in street name by
     Mr.  Coates  son, a minor.  Mr.  Coates is a director  of a  not-for-profit
     foundation which owns 5,000 shares.

(3)  Mr. William's  business  address is  Immuno Concepts,  9779  Business  Park
     Drive, Sacramento, CA 95827

(4)  Mr. Ruyan's business address is Hemagen  Diagnostics,  Inc, 34-40 Bear Hill
     Road, Waltham, MA 02451.

(5)  Mr. Christopher Coates' business address is: Ahlstrom Technical Specialties
     LLC, 122 West Butler Street, Mount Holly Springs, PA 17065.

(6) Mr. Christopher S. Coates and Mr. C. Robert Coates are brothers.


The  following  table shows the  purchases  and sales of  Northfield  stock held
beneficially and directly by Mr. Robert Coates:

                   MANAGEMENT INSIGHTS, INC.
        Shares of
        Northfield
        Common Stock  Action     Price            Date

           5,000       Buy        13 15/16         5/27/98
           2,000       Buy        15 3/8           6/5/98
          30,000       Buy        17 1/2           7/15/98
          20,000       Buy        17               7/15/98
          10,000       Buy        15 5/8           7/28/98
          14,000       Buy        13               8/21/98
           1,000       Buy        12 3/4           8/21/98
          95,000       Buy        13               8/24/98
           5,000       Buy        12 15/16         8/24/98
          15,000       Buy        12 1/2           8/26/98
          85,000       Buy        12 5/8           8/26/98



<PAGE>

                       C. ROBERT COATES
        Shares of
        Northfield
        Common Stock  Action     Price            Date

           5,000       Buy        15               6/12/98
          10,000       Buy        14 3/8           6/15/98
          10,000       Buy        14  7/16         6/15/98
           6,000       Buy        14  3/16         6/15/98
             200       Buy        14  5/16         6/16/98
          10,000       Buy        14 1/2           6/17/98
          10,000       Buy        14 3/8           6/18/98
          10,000       Buy        14 1/2           6/18/98
          10,000       Buy        14 1/8           6/19/98
           3,500       Buy        14  5/16         6/23/98
           2,000       Buy        14  5/16         6/24/98
           1,000       Buy        14 3/8           6/25/98
           1,100       Buy        14 1/2           6/26/98
           9,900       Buy        14 7/8           6/26/98
          10,000       Buy        15               6/29/98
           5,200       Buy        14 7/8           6/30/98
          10,000       Buy        15               7/1/98
           3,000       Buy        14 7/8           7/1/98
           6,600       Buy        14 5/8           7/2/98
           2,000       Buy        15 3/8           7/7/98
           2,500       Buy        15 3/8           7/9/98
           2,500       Buy        16               7/13/98
          10,000       Buy        16 1/2           7/14/98
           5,000       Buy        16 3/4           7/14/98
           3,600       Buy        16 3/4           8/4/98
         115,000       Buy        17.207           8/6/98
          65,000       Buy        17.289           8/7/98
          50,000       Buy        16 7/8           8/10/98
          13,900       Buy        17               8/10/98
          10,000       Sell       15 1/2           1/6/99
          10,000       Sell       15 3/8           1/6/99
           2,000       Sell       14  1/16         9/8/99
           1,000       Sell       14               9/8/99
           9,800       Sell       21               1/24/00
             100       Sell       21  3/16         1/24/00
           1,200       Sell       21 3/4           1/24/00
             100       Sell       21               1/25/00


                   SPENCER COATES, MINOR SON
        Shares of
        Northfield
        Common Stock  Action     Price            Date

             700       Buy        13 1/2           6/6/00
             450       Buy        13 5/8           6/6/00
             300       Buy        13  7/16         6/6/00
             300       Buy        12 5/8           6/6/00


                     NON-PROFIT FOUNDATION
        Shares of
        Northfield
        Common Stock  Action     Price            Date

                200    Buy        12 3/8           6/19/00
              1,600    Buy        12 7/16          6/20/00
                500    Buy        12 3/8           6/20/00
                500    Buy        12 3/8           6/21/00
              1,800    Buy        12 1/2           6/21/00
                400    Buy        12 5/8           6/21/00

<PAGE>


Except  as  described  above,  none  of our  nominees  have  purchased  or  sold
Northfield securities within the past two years.



                      SHARES OWNED BY CERTAIN STOCKHOLDERS
According to the Company's Proxy Statement,  filed August 18, 2000, two entities
each  beneficially  owned  more than five  percent of  Northfield's  outstanding
common stock. We know of no other  stockholder who beneficially owns more than 5
percent of Northfield's outstanding common stock.


                                                                     PERCENTAGE
                                                     NUMBER         BENEFICIALLY
                    NAME OF STOCKHOLDER             OF SHARES         OWNED(1)
                    -------------------             ---------       ------------

Richard E. DeWoskin...............................    717,715(2)        5.0%
Bruce S. Chelberg.................................  1,502,345(3)       10.5%
  c/o Whitman Corporation
  III Crossroad of Commerce
  3501 Algonquin Road
  Rolling Meadows, Illinois 60008
Whitman Corporation...............................  1,502,345          10.5%
  III Crossroads of Commerce
  3501 Algonquin Road
  Rolling Meadows, Illinois 60008



 (1)  Beneficial  ownership is determined  in  accordance  with the rules of the
      Securities  and  Exchange  Commission  and  generally  includes  voting or
      investment  power  with  respect  to  securities.  Shares of common  stock
      subject to stock options and warrants currently exercisable or exercisable
      within  60 days  are  deemed  outstanding  for  computing  the  percentage
      ownership of the person holding the options and the  percentage  ownership
      of any  group  of  which  the  holder  is a  member,  but are  not  deemed
      outstanding  for computing the  percentage  ownership of any other person.
      Except as indicated by footnote,  and subject to community  property  laws
      where  applicable,  the  persons  named in the table have sole  voting and
      investment  power  with  respect to all  shares of common  stock  shown as
      beneficially owned by them.

 (2)  Includes  75,000 shares of common stock which Mr.  DeWoskin is entitled to
      acquire  pursuant to stock options  currently  exercisable  or exercisable
      within 60 days.  Does not include  40,000  shares  acquirable  pursuant to
      stock options not currently exercisable or exercisable within 60 days.

 (3)  Includes shares of common stock held by Whitman Corporation.  Mr. Chelberg
      is the Chairman and Chief Executive Officer of Whitman Corporation.  Under
      the rules and regulations of the Securities and Exchange  Commission,  Mr.
      Chelberg  may be deemed a  beneficial  owner of the stock  held by Whitman
      Corporation. Mr. Chelberg disclaims beneficial ownership of the stock held
      by Whitman Corporation.



                                LEGAL PROCEEDINGS
There are no material pending legal  proceedings in which any of the nominees or
any other  participant or any of their respective  associates is a party adverse
to  Northfield  or any of its  affiliates or in which any of the nominees or any
other participant or any of their respective  associates has an interest adverse
to Northfield or any of its affiliates.

<PAGE>

ITEM 2. APPROVAL OF SELECTION OF INDEPENDENT AUDITORS

The  Company's  Board  of  Directors  has  selected  KPMG  LLP  as  Northfield's
independent  auditors for the fiscal year ending May 31,  2001,  and has further
directed that the selection of independent auditors be submitted for approval by
the stockholders at the annual meeting.

Representatives of KPMG LLP will be present at the annual meeting, will have the
opportunity to make a statement if they desire to do so and will be available to
respond to appropriate questions.


                           VOTING AND PROXY PROCEDURES
The  Company's  Board of Directors has fixed the close of business on August 14,
2000 as the record date for determining the stockholders of the Company entitled
to notice of and to vote at the Annual Meeting and any adjournment thereof. Only
stockholders  of record as of August 14, 2000 are entitled to vote at the Annual
Meeting. At each Annual Meeting, stockholders elect all the members of the Board
of Directors.

Based on  publicly  available  information,  C.  Robert  Coates  and  Management
Insights,  Inc.  believe  that  the only  outstanding  class  of  securities  of
Northfield  Laboratories Inc. is shares of Northfield's common stock.  According
to Northfield's  Proxy  Statement,  as of the record date, there were 14,242,375
shares of Northfield common stock issued and outstanding.


QUORUM

According to the Company's proxy statement,  each holder of record of shares who
is  entitled  to vote may cast one vote per share held on all  matters  properly
submitted for the vote of the stockholders at the annual meeting.  The presence,
in person or by proxy, of the holders of a majority of the outstanding shares of
common stock entitled to vote at the annual meeting is necessary to constitute a
quorum  at the  annual  meeting.  If a  stockholder  withholds  its vote for the
election of  directors  or abstains  from  voting on the other  proposals  to be
considered at the annual meeting,  the shares owned by that  stockholder will be
considered to be present at the annual meeting for purposes of establishing  the
presence or absence of a quorum for the transaction of business. There can be no
broker non-votes at this annual meeting.

REQUIRED VOTE

According to the Company's proxy  statement,  the affirmative vote of a majority
of the  votes  cast at the  annual  meeting  will be  required  to  approve  the
proposals  with  respect to the  election of directors  and the  appointment  of
independent auditors. Withheld votes and abstentions will be considered as votes
cast with  respect to these  proposals  and will have the same  effect as a vote
against these proposals.

According to the Company's proxy statement, if any nominee for director fails to
receive  the  affirmative  vote of a  majority  of the votes  cast at the annual
meeting, the majority of the directors then in office will be entitled under the
Company's  certificate of incorporation and bylaws to fill the resulting vacancy
in the board of directors.  Each director chosen in this manner will hold office
for a term expiring at the Company's next annual meeting of stockholders.

VOTING FOR FOUR NOMINEES

We are soliciting proxies for four directors.  We are not soliciting proxies for
six directors.  This means that at least two of Northfield's incumbent directors
can be elected if they received the requisite  majority vote as described  above
under  "Required  Vote." Election of all our nominees will constitute a majority
of the directors under Northfield's Certificate of Incorporation and By-Laws and
will allow our directors to approve all actions taken by the Board. There are no
supermajority or unanimous approval requirements in Northfield's  Certificate of
Incorporation or By-Laws for actions to be taken by the Board.

By using our proxy  only,  stockholders  will be voting for four  directors  and
giving up their right to vote for six directors.

We do not intend to replace  any of the  current  directors  if we are  elected.
Instead,  we leave that choice to our  stockholders.  The six directors with the
highest  number of votes will  serve on the Board,  assuming  they  receive  the
requisite majority vote. See "Required Vote."

There is a  possibility,  although we think it very  unlikely,  that none of the
current Northfield directors will serve on the Board with us. If we need to fill
two vacancies  because  Northfield's  elected  directors decide not to serve, we
will seek out retired senior managers of major pharmaceutical companies that are
not direct or indirect competitors of Northfield.

If three of our nominees are elected along with three incumbent directors, we do
not know what the possible  effect  would be of a split Board.  If a split Board
persists,  we may not be able to implement the proposals  discussed in the proxy
materials or any other proposals  brought before the Board and we cannot predict
the impact  this  would have on  Northfield.  Nevertheless,  we believe  that no
director  should be tied to or loyal to any officer or other board  member,  but
should instead hold all officers and directors  accountable to the stockholders,
employees and customers of Northfield.

If only four nominees are elected, in accordance with the Company's  Certificate
of Incorporation and By-Laws, a majority of the directors then in office will be
entitled to fill the  resulting  vacancies  in the Board of  Directors.  See the
second paragraph under "Required Vote."


PROXY PROCEDURES

C. Robert Coates and Management  Insights,  Inc. urge all stockholders to attend
the Annual Meeting in person.


Any stockholder  executing a proxy has the power to revoke it at any time before
it is voted.  A proxy may be revoked by filing with the Secretary of the Company
a written  notice of  revocation,  by delivering a duly executed proxy bearing a
later date or by attending the Annual Meeting and/or by voting in person. If you
have already  executed the  Company's  proxy card,  you may revoke that proxy by
executing  the  enclosed  BLUE proxy card and  returning  it to the  appropriate
address.


Please  sign and  date the  enclosed  BLUE  proxy  card,  and  return  it in the
postage-paid  envelope as promptly as possible.  By returning  the enclosed BLUE
proxy  card,  stockholders  will be able to vote on the  election  of C.  Robert
Coates, Bert R. Williams III, Jerry L. Ruyan, and Christopher S. Coates.

<PAGE>


PLEASE SIGN, DATE AND RETURN TODAY THE ENCLOSED BLUE PROXY CARD TO:
Beacon Hill Partners
90 Broad Street
New York, NY 10004

                  If any of the individuals  nominated becomes unavailable,  the
proxies  received will be voted for the  remaining  nominees or for a substitute
nominee selected by C. Robert Coates and Management Insights, Inc.


PLEASE VOTE TO ELECT THE  NOMINEES--  C. ROBERT  COATES,  BERT R.  WILLIAMS III,
JERRY L. RUYAN, AND CHRISTOPHER S. COATES.


                            SOLICITATION INFORMATION
C.  Robert  Coates and  Management  Insights,  Inc.  have  retained  Beacon Hill
Partners  for  solicitation  and  advisory  services  in  connection  with  this
solicitation.  Under the agreement with Beacon Hill  Partners,  Beacon Hill will
receive  a fee  estimated  not to exceed  $75,000,  plus  reimbursement  for its
reasonable  out-of-pocket  expenses.  C. Robert  Coates has agreed to  indemnify
Beacon Hill against certain  liabilities and expenses.  Beacon Hill Partners may
employ up to 25 to 30 people in connection with the  solicitation of proxies for
the  Annual  Meeting.  Proxies  will be  solicited  by mail,  courier  services,
Internet,  advertising,  telephone or telecopier or in person. We also intend to
use agents and employees of Management Insights, Inc., without compensation,  to
solicit proxies by telephone, mail, or in person.


C. Robert  Coates and  Management  Insights,  Inc. are bearing the costs of this
solicitation. The total expenditures to date in preparation for the solicitation
of stockholders  are  approximately  $25,000.  The total  expenditures  for this
solicitation are expected to be approximately  $250,000.  We currently intend to
seek  reimbursement  from  Northfield for the reasonable  expenses in connection
with this  solicitation  but do not  expect to  submit  the  matter to a vote of
security holders, unless required by law.



                    OTHER MATTERS AND ADDITIONAL INFORMATION
Except as described above,  none of the nominees or any other participant or any
associate  of the  nominees,  directly  or  indirectly  owns any  securities  of
Northfield or any subsidiary of Northfield  beneficially  or of record,  has the
right to acquire  beneficial  ownership within 60 days, or has purchased or sold
such securities within the past two years.

Except as described above, none of the nominees or any other participant has any
substantial interest,  direct or indirect, by security holdings or otherwise, in
any matter to be acted upon at the Annual  Meeting,  except for the  election of
directors.

No part of the purchase price of any of the shares of common stock  beneficially
owned by any of the nominees or any other  participant  is  represented by funds
borrowed or  otherwise  obtained  for the purpose of  acquiring  or holding such
securities.

None of the  nominees or any other  participant  is, or within the past year has
been, a party to any contract, arrangement or understanding with any person with
respect to any securities of Northfield.

None of the nominees has engaged in any  transaction  or series of  transactions
since the beginning of Northfield's  last fiscal year or has currently  proposed
any  transaction,  to which  Northfield or any of its  subsidiaries  is a party,
where the amount involved was in excess of $60,000.

None of the nominees has been indebted to Northfield or any of its  subsidiaries
at any time since the beginning of Northfield's last fiscal year.

None of the nominees or any other  participant or any associate of the nominees,
has any  arrangement  or  understanding  with any person (A) with respect to any
future  employment by Northfield or (B) with respect to any future  transactions
to which Northfield or any of the affiliates will or may be a party.

None of the nominees or any other  participant holds any position or office with
Northfield or any parent,  subsidiary,  or affiliate of Northfield,  and none of
the  nominees  or any  other  participant  has  ever  served  as a  director  of
Northfield or any parent,  subsidiary,  or affiliate of  Northfield.  Management
Insights, Inc. is not an affiliate of Northfield Laboratories, Inc.

Except as described above, none of the nominees or any other participant has any
family relationship, by blood, marriage, or adoption, to any director, executive
officer,  or person  nominated or chosen by  Northfield  to become a director or
executive  officer  of  Northfield.  During  the last  three  fiscal  years,  no
compensation  was awarded to,  earned by, or paid to any of the  nominees or any
other  participant  by any person for any  services  rendered in any capacity to
Northfield or its subsidiaries.

<PAGE>

None  of  the  nominees  or  any  other   participant  has  any  arrangement  or
understanding  with any  nominee  or any  other  person  pursuant  to which  the
nominations were made,  other than each nominee's  agreement to be nominated and
to serve as a director if elected.


C. Robert  Coates and  Management  Insights,  Inc. are not aware of any business
other than as set forth in this Proxy Statement and Northfield's proxy materials
that will be presented at the Annual Meeting.  Should other proposals be brought
before the Annual  Meeting about matters  unknown to the  stockholders  within a
reasonable  time before this  solicitation,  the persons named as proxies on the
enclosed BLUE proxy card will vote on such matters at their discretion.


The information concerning Northfield contained in this Proxy Statement has been
taken from, and is based upon, publicly available information.


                 PROCEDURE FOR SUBMITTING STOCKHOLDER PROPOSALS
The Company's proxy  statement  indicates that  stockholders  may present proper
proposals for inclusion in Northfield's proxy statement and for consideration at
the next  annual  meeting of the  Company's  stockholders  by  submitting  their
proposals  to the  Company in a timely  manner.  In order to be  included in the
Company's  proxy statement for its next annual  meeting,  stockholder  proposals
must be received by the Company no later than April 20, 2001, and must otherwise
comply with the  requirements  of the  applicable  rules of the  Securities  and
Exchange  Commission.  In addition,  the Company's  bylaws  establish an advance
notice procedure with regard to certain matters, including stockholder proposals
not included in our proxy statement,  to be brought before any annual meeting of
stockholders.  In general,  notice must be received by the  Company's  corporate
secretary  not less than 60 days nor more than 90 days  prior to the date of the
annual meeting,  except if less than 70 days' notice or prior public  disclosure
of the date of the meeting is given or made to our stockholders,  in which event
notice by the stockholders to be timely must be received no later than the close
of business on the tenth day  following  the date on which notice of the date of
the annual  meeting was mailed or public  disclosure  was made.  It is currently
expected that the 2001 annual meeting of  stockholders  will be held on or about
October 11, 2001. Therefore, the deadline for timely submission of a stockholder
proposal for  consideration at the 2001 annual meeting is currently  expected to
be August 12, 2001.


All notice of  proposals by  stockholders,  whether or not to be included in the
Company's proxy materials,  should be sent to Northfield Laboratories Inc., 1560
Sherman Avenue, Suite 1000, Evanston, Illinois 60201-4800,  Attention: Corporate
Secretary.

================================================================================
                                    IMPORTANT
Your vote is important.  No matter how many shares you own,  please give us your
proxy FOR the election of the nominees by taking the following steps:

    1. SIGN the enclosed BLUE proxy card;

    2. DATE the enclosed BLUE proxy card;

    3. MAIL the  enclosed  BLUE proxy card TODAY in the  envelope  provided  (no
    postage is necessary if mailed in the United States); or

    4.  CONTACT your broker and instruct the broker to execute a BLUE proxy card
    FOR the election of the Committee's nominees.

If any of your  shares  are held in the name of a  brokerage  firm,  bank,  bank
nominee or other institution, only it can vote such shares and only upon receipt
of your specific  instructions.  Accordingly,  we recommend  that you return the
BLUE proxy card  provided by your broker or contact the person  responsible  for
your  account  and  instruct   that  person  to  execute  the  BLUE  proxy  card
representing your shares.


<PAGE>

If you have any  questions or require  additional  information,  please  contact
Beacon Hill Partners,  90 Broad Street, New York, NY 10004. You can also contact
Beacon Hill  Partners by calling  toll free  1(800)  755-5501,  or by e-mail at:
[email protected]


     PLEASE VOTE FOR C. ROBERT COATES, BERT R. WILLIAMS III, JERRY L. RUYAN, AND
     CHRISTOPHER S. COATES.

                                              Sincerely,

                                              C. Robert Coates and
                                              Management Insights, Inc.



================================================================================

    DEFINITIVE COPY INTENDED TO BE RELEASED
    TO SECURITY HOLDERS ON SEPTEMBER __, 2000

    NORTHFIELD LABORATORIES INC.
    2000 ANNUAL MEETING OF STOCKHOLDERS
    THIS PROXY IS SOLICITED BY C.ROBERT COATES AND MANAGEMENT INSIGHTS, INC.




    The  undersigned  hereby appoints C. Robert Coates and Bert R. Williams III,
    as  attorneys  and agents  with full power of  substitution  as proxy of the
    undersigned  at the  2000  Annual  Meeting  of  Stockholders  of  Northfield
    Laboratories Inc.  ("Northfield" or the "Company"),  to be held at 9:00 a.m.
    local time on October 12, 2000,  at the  Company's  corporate  headquarters,
    1560  Sherman  Avenue,  Suite  1000,  Evanston,  IL  60201-4800,  or at  any
    postponement  or  rescheduling,  and to vote all  shares of common  stock of
    Northfield Laboratories Inc,, that the undersigned would be entitled to vote
    if personally  present.  The undersigned hereby revokes any previous proxies
    with respect to the matters covered by this proxy.

    VOTING

    [X] PLEASE MARK YOUR VOTES AS IN THIS EXAMPLE

ITEM 1:
      C. ROBERT COATES AND MANAGEMENT INSIGHTS, INC. RECOMMEND VOTING FOR C.
      ROBERT COATES, BERT R. WILLIAMS III, JERRY L. RUYAN, AND CHRISTOPHER S.
      COATES TO SERVE AS DIRECTORS.



C. Robert Coates   Bert R. Williams III   Jerry L. Ruyan   Christopher S. Coates

[ ] Vote For All Nominees   [ ] Withhold Authority to Vote for    [ ] Exceptions
                            All Nominees


       (INSTRUCTIONS:  TO WITHHOLD AUTHORITY TO VOTE FOR ANY INDIVIDUAL NOMINEE,
       MARK THE "EXCEPTIONS" BOX AND STRIKE A LINE THROUGH THAT NOMINEE'S NAME.)

       THE SHARES  REPRESENTED BY THIS PROXY WILL BE VOTED AS SPECIFIED  HEREIN.
       WHERE NO VOTING  INSTRUCTIONS ARE GIVEN,  THE SHARES  REPRESENTED BY THIS
       PROXY WILL BE VOTED FOR C.ROBERT  COATES,  BERT R. WILLIAMS III, JERRY L.
       RUYAN, AND CHRISTOPHER S. COATES.


<PAGE>

ITEM 2:
         C. ROBERT COATES AND MANAGEMENT INSIGHTS, INC.  RECOMMEND  VOTING TO
         APPROVE THE APPOINTMENT OF KPMG LLP AS INDEPENDENT AUDITORS OF THE
         COMPANY TO SERVE FOR THE COMPANY'S 2001 FISCAL YEAR.

       [  ] FOR                   [  ] AGAINST                      [  ] ABSTAIN


       In their  discretion,  C.  Robert  Coates  and Bert R.  Williams  III are
       authorized  to vote upon such other  business as may properly come before
       the Annual  Meeting or any  adjournment,  postponement  or  rescheduling,
         about  matters  unknown to the  stockholders  within a reasonable  time
before this solicitation.

       Please date and sign this proxy exactly as your name appears hereon:


                                                Dated: ___________________, 2000


================================================================================
                                   (Signature)


================================================================================
                          (Signature, if held jointly)





================================================================================
                                     (Title)

                                        When  shares are held by joint  tenants,
                                        both  should   sign.   When  signing  as
                                        attorney-in-fact,              executor,
                                        administrator,     trustee,    guardian,
                                        corporate  officer  or  partner,  please
                                        give   full   title   as   such.   If  a
                                        corporation,  please  sign in  corporate
                                        name by  President  or other  authorized
                                        officer.  If a partnership,  please sign
                                        in   partnership   name  by   authorized
                                        person.

           PLEASE MARK, SIGN, DATE AND RETURN THIS PROXY CARD PROMPTLY
                       IN THE ENCLOSED ENVELOPE PROVIDED.







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