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FORM 4 OMB APPROVAL
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[ ] Check this box if no OMB Number: 3235-0287
longer subject to Expires: April 30, 1998
Section 16. Form 4 Estimated average burden
or Form 5 obligations hours per response .... 0.5
may continue. See ---------------------------
Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
Section 17(a) of the Public Utility Holding Company Act of 1935
or Section 30(f) of the Investment Company Act of 1940
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<S> <C> <C> <C> <C> <C> <C>
(Print or Type Responses)
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1. Name and Address of Reporting Person* 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person(s)
Pedersen, Gary W. ZYMETX, Inc. "ZMTX" to Issuer (Check all applicable)
- --------------------------------------------- ---------------------------------------------- Director 10% Owner
(Last) (First) (Middle) 3. IRS or Social Security 4. Statement for ---- ---
Number of Reporting Month/Year X Officer (give Other (Specify
Rt. 3, Box 145 Person (voluntary) 8/98 ---- title --- below)
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(Street) 5. If Amendment,
Meeker, OK 74055 ###-##-#### Date of Original Vice President of Marketing and Sales
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(City) (State) (Zip) 7. Individual or Joint/Group Filing
------------- (Check Applicable Line)
X Form filed by One Reporting
--- Person
Form filed by More than One
--- Reporting Person
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TABLE I -- NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
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1. Title of Security 2. Trans- 3. Transac- 4. Securities Acquired (A) 5. Amount of Se- 6. Owner- 7. Nature
(Instr. 3) action tion or Disposed of (D) curities Benefi- ship of In-
Date Code (Instr. 3, 4 and 5) cially Owned at Form: direct
(Instr. 8) End of Month Direct Benefi-
(Month/ (Instr. 3 and 4) (D) or cial
Day/ --------------------------------------- Indirect Owner-
Year) Code V Amount (A) or Price (I) ship
(D) (Instr. 4) (Instr.
4)
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Common Stock 10/27/97 P 551 A $8.00 551 D N/A
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par value $.001
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per share
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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. Page 1 of 2
* If the form is filed by more than one reporting person, see Instruction 4(b)(v). SEC 1474 (7-96)
POTENTIAL PERSONS WHO ARE TO RESPOND TO THE COLLECTIONS OF INFORMATION
CONTAINED IN THIS FORM ARE NOT REQUIRED TO RESPOND UNLESS THE FORM DISPLAYS
A CURRENTLY VALID OMB CONTROL NUMBER.
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FORM 4 (CONTINUED) TABLE II -- DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
(E.G., PUTS, CALLS, WARRANTS, OPTIONS, CONVERTIBLE SECURITIES)
<S> <C> <C> <C> <C> <C> <C> <C> <C>
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1. Title of Derivative 2. Conver- 3. Trans- 4. Trans- 5. Number of 6. Date Exer- 7. Title and Amount 8. Price
Security sion or action action Derivative cisable and of Underlying of
(Instr. 3) Exercise Date Code Securities Ac- Expiration Securities Deriv-
Price of (Month/ (Instr. 8) quired (A) or Date (Instr. 3 and 4) ative
Deriv- Day/ Disposed of (D) (Month/Day/ Secur-
ative Year) (Instr. 3, 4, Year) ity
Security and 5)
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Date Expira- Amount or
-------------------------- Exer- tion Title Number of
Code V (A) (D) cisable Date Shares
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Incentive Stock Options $2.00 [no transaction for the period of this report] 6/5/98 (1) 6/5/07 Common Stock 20,000(2)
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Incentive Stock Options $4.94 8/18/98 A 3,350 8/18/99(3) 8/18/08 Common Stock 3,350(2)
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<C> <C> <C>
9. Number of 10. Ownership 11. Nature of
Derivative Form of Indirect
Securities Derivative Beneficial
Beneficially Security: Ownership
Owned at End Direct (D) (Instr. 4)
of Month or Indirect (I)
(Instr. 4) (Instr. 4)
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20,000 D N/A
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3,350 D N/A
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Explanation of Responses:
(1) Vest at a rare of 25% per year on June 5, 1998, June 5, 1999, June 5, 2000 and June 5, 2001
(2) Issued under the Zyme, TX, Inc. Stock Option Plan in consideration of Mr. Pederson's services as a key
employee.
(3) Vest at a rate of 25% per year on August 18, 1999, August 18, 2000, August 18, 2001 and August 18, 2002.
/s/ Gary W. Pederson 9/10/98
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**Signature of Reporting Person Date
Note: File three copies of this Form, one of which must be manually signed. Page 2 of 2
If space provided is insufficient, see Instruction 6 for procedure. SEC 1474 (7-96)
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