UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 3
INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES
1. Name and Address of Reporting Person
TOLBERT III, JAMES R.
PO BOX 1533
OKLAHOMA CITY, OK USA 73101
2. Date of Event Requiring Statement (Month/Day/Year)
6/1/99
3. IRS Identification Number of Reporting Person, if an entity (voluntary)
4. Issuer Name and Ticker or Trading Symbol
ZYMETX, INC. ZMTX
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)
(x) Director ( ) 10% Owner ( ) Officer (give title below)
( ) Other (specify below)
6. If Amendment, Date of Original (Month/Day/Year)
7. Individual or Joint/Group Filing (Check applicable line)
(x) Form Filed by One Reporting Person
( ) Form Filed by More than One Reporting Person
<TABLE>
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Table I -- Non-Derivative Securities Beneficially Owned
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1. Title of Security |2. Amount of |3. Ownership |4. Nature of Indirect |
| Securities | Form: | Beneficial Ownership |
| Beneficially | Direct(D) or | |
| Owned | Indirect(I) | |
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<S> <C> <C> <C>
<CAPTION>
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Table II -- Derivative Securities Beneficially Owned |
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1.Title of Derivative |2.Date Exer- |3.Title and Amount | |4. Conver-|5. Owner- |6. Nature of Indirect |
Security | cisable and | of Underlying | |sion or |ship: | Beneficial Ownership |
| Expiration | Securities | |exercise |Form of | |
| Date(Month/ |-----------------------|---------|price of |Deriv- | |
| Day/Year) | |Amount |deri- |ative | |
| Date | Expira- | |or |vative |Security: | |
| Exer- | tion | Title |Number of|Security |Direct(D) or | |
| cisable | Date | |Shares | |Indirect(I) | |
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<S> <C> <C> <C> <C> <C> <C> <C>
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Non-Qualified Stock |6/1/00 |6/1/09 |COMMON STOCK, par value|40,000 |2.0625 [2]|D | |
Options 6-99 |[1] | |$.001 | | | | |
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Explanation of Responses:
1. Vests at a rate of 33 1/3% per year on June 1, 2000, June 1, 2001, and June
1, 2002.
2. Issued under the ZymeTx, Inc. Stock Option Plan in consideration of Mr.
Tolbert's service as a Director of the Issuer.
/s/ James R. Tolbert III
SIGNATURE OF REPORTING PERSON
/Signature/
James R. Tolbert III
DATE
6/7/99
