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<PAGE> 1 EXHIBIT 23.1 CONSENT OF COUNSEL Phillips McFall McCaffrey McVay & Murrah, P.C., hereby consents to the filing of its opinion of counsel as an exhibit to the Form S-3 Registration Statement of ZymeTx, Inc. (the "Company") for the registration of 1,621,038 shares of common stock, par value $.001 per share, of the Company. PHILLIPS MCFALL MCCAFFREY MCVAY & MURRAH, P.C. /s/ Phillips McFall McCaffrey McVay & Murrah, P.C. Oklahoma City, Oklahoma November 30, 2000
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