CV THERAPEUTICS INC
SC 13G/A, 1998-02-11
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  Schedule 13G
                                 (Rule 13d-102)

             INFORMATION STATEMENT PURSUANT TO RULES 13d-1 AND 13d-2
                    UNDER THE SECURITIES EXCHANGE ACT OF 1934
                                (Amendment No.1)*



                              CV Therapeutics, Inc.
- --------------------------------------------------------------------------------
                                (Name of Issuer)


                                  Common Stock
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                   126667 10 4
- --------------------------------------------------------------------------------
                                 (CUSIP Number)




*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                         (Continued on following pages)





                                Page 1 of 9 Pages


<PAGE>



<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- ---------------------------------------------------------                    ---------------------------------------
CUSIP NO.  126667 10 4                                          13 G                   Page 2 of 9 Pages
- ---------------------------------------------------------                    ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING PERSONS
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                     Delphi Ventures II, L.P. ("DV II")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a)   [ ]        (b)   [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
- ----------------------------------- -------- -----------------------------------------------------------------------

               NUMBER OF            5        SOLE VOTING POWER 
                SHARES                       27,394  shares,  except that DMP II, the general  partner of DVII,  and
             BENEFICIALLY                    Bochnowski,  Douglass, and Lothrop, the general partners of DMP II, may
            OWNED BY EACH                    be deemed to have shared power to vote these shares.                   
               REPORTING                     
                PERSON                 
                 WITH    
                                    -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER
                                             See response to row 5.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER 
                                             27,394  shares,  except that DMP II, the general  partner of DVII,  and
                                             Bochnowski,  Douglass, and Lothrop, the general partners of DMP II, may
                                             be deemed to have shared power to dispose of these shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER   
                                             See response to row 7.

- ----------- --------------------------------------------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       27,394
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                      [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   .44%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*
                                                                                                   PN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>


<PAGE>

<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- ---------------------------------------------------------                    ---------------------------------------
CUSIP NO. 126667 10 4                                           13 G                   Page 3 of 9 Pages
- ---------------------------------------------------------                    ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING PERSONS
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                     Delphi BioInvestments II, L.P. ("DBI II")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a) [ ]          (b) [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
- ----------- --------------------------------------------------------------------------------------------------------
               NUMBER OF            5        SOLE VOTING POWER
                SHARES                       139  shares,  except  that DMP II, the  general  partner of DBI II, and
             BENEFICIALLY                    Bochnowski,  Douglass, and Lothrop, the general partners of DMP II, may
             OWNED BY EACH                   be deemed to have shared power to vote these shares.                   
               REPORTING                     
                PERSON    
                 WITH     
                                    -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER
                                             See response to row 5.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER
                                             139  shares,  except  that DMP II, the  general  partner of DBI II, and
                                             Bochnowski,  Douglass, and Lothrop, the general partners of DMP II, may
                                             be deemed to have shared power to dispose of these shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER
                                             See response to row 7.

- ----------- --------------------------------------------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       139
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                      [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   0.00%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*
                                                                                                   PN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>



<PAGE>

<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- ---------------------------------------------------------                    ---------------------------------------
CUSIP NO. 126667 10 4                                           13 G                   Page 4 of 9 Pages
- ---------------------------------------------------------                    ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING PERSONS
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS
                     Delphi Management Partners II, L.P. ("DMP II")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a)   [ ]           (b)   [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
- ----------------------------------- -------- -----------------------------------------------------------------------
              NUMBER OF             5        SOLE VOTING POWER
               SHARES                        0 shares.
            BENEFICIALLY 
            OWNED BY EACH
              REPORTING  
               PERSON    
                WITH                -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER
                                             27,533 shares,  of which 27,394 are directly owned by DV II and 139 are
                                             directly  owned by DBI II. DMP II is the  general  partner of DV II and
                                             DBI II and may be deemed to have shared power to vote these shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER
                                             27,533 shares,  of which 27,394 are directly owned by DV II and 139 are
                                             directly  owned by DBI II. DMP II is the  general  partner of DV II and
                                             DBI II and may be  deemed  to have  shared  power to  dispose  of these
                                             shares.

- ----------- --------------------------------------------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       27,533
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                       [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   .44%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*
                                                                                                   PN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>


<PAGE>


<TABLE>
<CAPTION>

<S>                                                             <C>          <C>
- ---------------------------------------------------------                    ---------------------------------------
CUSIP NO. 126667 10 4                                           13 G                   Page 5 of 9 Pages
- ---------------------------------------------------------                    ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING PERSONS
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS
                     James J. Bochnowski ("Bochnowski")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a)  [ ]         (b)   [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            U.S. Citizen
- ----------------------------------- -------- -----------------------------------------------------------------------
              NUMBER OF             5        SOLE VOTING POWER
               SHARES                        2,315 shares.
            BENEFICIALLY 
            OWNED BY EACH
              REPORTING  
               PERSON    
                WITH                -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER
                                             27,533 shares,  of which 27,394 are directly owned by DV II and 139 are
                                             directly  owned by DBI II. DMP II is the  general  partner of DV II and
                                             DBI II, and  Bochnowski,  a general partner of DMP II, may be deemed to
                                             have shared power to vote these shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE  DISPOSITIVE  POWER
                                             2,933 shares.
                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER
                                             27,533 shares,  of which 27,394 are directly owned by DV II and 139 are
                                             directly  owned by DBI II. DMP II is the  general  partner of DV II and
                                             DBI II, and  Bochnowski,  a general partner of DMP II, may be deemed to
                                             have shared power to dispose of these shares.

- ----------- --------------------------------------------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       29,848
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                      [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   .48%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*
                                                                                                   IN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>


<PAGE>


<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- ---------------------------------------------------------                    ---------------------------------------
CUSIP NO. 126667 10 4                                           13 G                   Page 6 of 9 Pages
- ---------------------------------------------------------                    ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING PERSONS
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS
                     David L. Douglass ("Douglass")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a)  [ ]         (b)  [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            U.S. Citizen
- ----------------------------------- -------- -----------------------------------------------------------------------
              NUMBER OF             5        SOLE VOTING POWER
               SHARES                        0 shares.
            BENEFICIALLY 
            OWNED BY EACH
              REPORTING  
               PERSON    
                WITH                -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER
                                             27,533 shares,  of which 27,394 are directly owned by DV II and 139 are
                                             directly  owned by DBI II. DMP II is the  general  partner of DV II and
                                             DBI II,  and  Douglass,  a general  partner of DMP II, may be deemed to
                                             have shared power to vote these shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER
                                             27,533 shares, of which 27,3994 are directly owned by DV II and 139 are
                                             directly  owned by DBI II. DMP II is the  general  partner of DV II and
                                             DBI II,  and  Douglass,  a general  partner of DMP II, may be deemed to
                                             have shared power to dispose of these shares.

- ----------- --------------------------------------------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       27,533
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                      [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   .44%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*                                                              IN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>


<PAGE>

<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- ---------------------------------------------------------                    ---------------------------------------
CUSIP NO. 126667 10 4                                           13 G                   Page 7 of 9 Pages
- ---------------------------------------------------------                    ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------

1           NAME OF REPORTING PERSONS
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS
                     Donald J. Lothrop ("Lothrop")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a)  [ ]            (b)  [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            U.S. Citizen
- ----------------------------------- -------- -----------------------------------------------------------------------
              NUMBER OF             5        SOLE VOTING POWER
               SHARES                        90 shares.
            BENEFICIALLY 
            OWNED BY EACH
              REPORTING  
               PERSON    
                WITH                -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER
                                             27,533 shares,  of which 27,394 are directly owned by DV II and 139 are
                                             directly  owned by DBI II. DMP II is the  general  partner of DV II and
                                             DBI II, and Lothrop, a general partner of DMP II, may be deemed to have
                                             shared power to vote these shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER
                                             90 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER
                                             27,533 shares,  of which 27,394 are directly owned by DV II and 139 are
                                             directly  owned by DBI II. DMP II is the  general  partner of DV II and
                                             DBI II, and Lothrop, a general partner of DMP II, may be deemed to have
                                             shared power to dispose of these shares.

- ----------- --------------------------------------------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       27,623
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                      [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   0.45%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*                                                              IN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>


<PAGE>




                                                               Page 8 of 9 Pages


                  This  Statement  amends the  Statement on Schedule  13(G) (the
                  "Original  Statement")  filed by Delphi  Ventures  II, L.P., a
                  Delaware limited partnership ("DV II"), Delphi  BioInvestments
                  II, L.P. ("DBI II"),  Delphi  Management  Partners II, L.P., a
                  Delaware limited  partnership  ("DMP II"), James J. Bochnowski
                  ("Bochnowski"),  David L. Douglass ("Douglass"), and Donald J.
                  Lothrop  ("Lothrop").  The foregoing  entities and individuals
                  are collectively  referred to as the "Reporting Persons." Only
                  those Items as to which there has been a change of Information
                  are included in this Amendment.

                  DMP II is the general  partner of DV II and DBI II, and may be
                  deemed  to have  shared  power  to vote  and  shared  power to
                  dispose  of shares of the issuer  directly  owned by DV II and
                  DBI II.  Bochnowski,  Douglass  and  Lothrop  are the  general
                  partners of DMP II, and may be deemed to have shared  power to
                  vote and  shared  power to  dispose  of the  shares  of issuer
                  directly owned by DV II and DBI II.

ITEM 4.           OWNERSHIP:

                  The following information with respect to the ownership of the
                  Common  Stock  of  the  issuer  by  the  persons  filing  this
                  Statement is provided as of December 31, 1997:

                    (a)      Amount beneficially owned:

                                   See Row 9 of cover  page  for each  Reporting
                                   Person.

                    (b)      Percent of Class:

                                   See Row 11 of cover  page for each  Reporting
                                   Person.

                    (c) Number of shares as to which such person has:

                           (i)  Sole power to vote or to direct the vote:

                                   See Row 5 of cover  page  for each  Reporting
                                   Person.

                          (ii)  Shared power to vote or to direct the vote:

                                   See Row 6 of cover  page  for each  Reporting
                                   Person.

                         (iii)  Sole power to dispose or to direct 
                                the disposition of:

                                   See Row 7 of cover  page  for each  Reporting
                                   Person.

                          (iv)  Shared power to dispose or to direct the 
                                disposition of:

                                   See Row 8 of cover  page  for each  Reporting
                                   Person.


<PAGE>




                                                               Page 9 of 9 Pages




ITEM 5.           OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS:

                  If this statement is being filed to report the fact that as of
                  the date  hereof,  the  reporting  person has ceased to be the
                  beneficial  owner of more  than five  percent  of the class of
                  securities, check the following:     [X]


                                   SIGNATURES

                  After  reasonable  inquiry and to the best of my knowledge and
belief,  I certify  that the  information  set forth in this  statement is true,
complete and correct.

Dated:  February 6, 1998




                                   /s/ James J. Bochnowski
                                   ---------------------------------------------
                                   James  J.  Bochnowski,  individually,  and on
                                   behalf of DVII,  in his capacity as a general
                                   partner  of DMP II,  the  general  partner of
                                   DVII, on behalf of DBI II, in his capacity as
                                   a  general  partner  of DMP II,  the  general
                                   partner of DBI II, and on behalf of DMP II in
                                   his capacity as a general partner thereof.





                                   /s/ David L. Douglass
                                   ---------------------------------------------
                                   David L. Douglass





                                   /s/ Donald J. Lothrop
                                   ---------------------------------------------
                                   Donald J. Lothrop






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