CV THERAPEUTICS INC
S-3, EX-25.1, 2000-06-02
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                                                                  Exhibit 25.1
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                          -----------------------------

                                    FORM T-1

                            STATEMENT OF ELIGIBILITY
                   UNDER THE TRUST INDENTURE ACT OF 1939 OF A
                    CORPORATION DESIGNATED TO ACT AS TRUSTEE

                          -----------------------------

 __ CHECK IF AN APPLICATION TO DETERMINE ELIGIBILITY OF A TRUSTEE PURSUANT TO
                               SECTION 305(b) (2)

                  NORWEST BANK MINNESOTA, NATIONAL ASSOCIATION
               (Exact name of trustee as specified in its charter)

A U.S. NATIONAL BANKING ASSOCIATION                        41-1592157
(Jurisdiction of incorporation or                          (I.R.S. Employer
organization if not a U.S. national                        Identification No.)
bank)

SIXTH STREET AND MARQUETTE AVENUE
Minneapolis, Minnesota                                     55479
(Address of principal executive offices)                   (Zip code)

                       Stanley S. Stroup, General Counsel
                  NORWEST BANK MINNESOTA, NATIONAL ASSOCIATION
                        Sixth Street and Marquette Avenue
                          Minneapolis, Minnesota 55479
                                 (612) 667-1234
                               (Agent for Service)

                          -----------------------------

                              CV THERAPEUTICS, INC.
               (Exact name of obligor as specified in its charter)

DELAWARE                                                   43-1570294
(State or other jurisdiction of                            (I.R.S. Employer
incorporation or organization)                             Identification No.)

3172 PORTER DRIVE
PALO ALTO, CALIFORNIA                                      94304
(Address of principal executive offices)                   (Zip code)

                          -----------------------------
                  4.75% CONVERTIBLE SUBORDINATED NOTES DUE 2007
                       (Title of the indenture securities)

================================================================================


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Item 1. GENERAL INFORMATION. Furnish the following information as to the
trustee:

         (a)      Name and address of each examining or supervising authority to
                  which it is subject.

                  Comptroller of the Currency
                  Treasury Department
                  Washington, D.C.

                  Federal Deposit Insurance Corporation
                  Washington, D.C.

                  The Board of Governors of the Federal Reserve System
                  Washington, D.C.

         (b)      Whether it is authorized to exercise corporate trust powers.

                  The trustee is authorized to exercise corporate trust powers.

Item 2. AFFILIATIONS WITH OBLIGOR. If the obligor is an affiliate of the
trustee, describe each such affiliation.

                  None with respect to the trustee.

No responses are included for Items 3-14 of this Form T-1 because the obligor is
not in default as provided under Item 13.

Item 15. FOREIGN TRUSTEE.     Not applicable.

Item 16. LIST OF EXHIBITS.    List below all exhibits filed as a part of this
                              Statement of Eligibility.  Norwest Bank
                              incorporates by reference into this Form T-1 the
                              exhibits attached hereto.

       Exhibit 1.   a.        A copy of the Articles of Association of the
                              trustee now in effect.*

       Exhibit 2.   a         A copy of the certificate of authority of the
                              trustee to commence business issued June 28,
                              1872, by the Comptroller of the Currency to The
                              Northwestern National Bank of Minneapolis.*

                    b.        A copy of the certificate of the Comptroller of
                              the Currency dated January 2, 1934, approving
                              the consolidation of The Northwestern National
                              Bank of Minneapolis and The Minnesota Loan and
                              Trust Company of Minneapolis, with the
                              surviving entity being titled Northwestern
                              National Bank and Trust Company of Minneapolis.*

                    c.        A copy of the certificate of the Acting
                              Comptroller of the Currency dated January 12,
                              1943, as tochange of corporate title of
                              NorthwesternNational Bank and Trust Company of
                              Minneapolis to Northwestern National Bank of
                              Minneapolis.*

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                    d.        A copy of the letter dated May 12, 1983 from the
                              Regional Counsel, Comptroller of the Currency,
                              acknowledging receipt of notice ofname change
                              effective May 1, 1983 fromNorthwestern National
                              Bank of Minneapolis toNorwest Bank Minneapolis,
                              National Association.*

                    e.        A copy of the letter dated January 4, 1988 from
                              the Administrator of National Banks for the
                              Comptroller of the Currency certifying approval
                              of consolidation and merger effective January
                              1, 1988 of Norwest Bank Minneapolis, National
                              Association with various other banks under the
                              title of "Norwest Bank Minnesota, National
                              Association."*

          Exhibit 3. A copy of the authorization of the trustee to exercise
                     corporate trust powers issued January 2, 1934, by the
                     Federal Reserve Board.*

          Exhibit 4. Copy of By-laws of the trustee as now in effect.*

          Exhibit 5. Not applicable.

          Exhibit 6. The consent of the trustee required by Section 321(b) of
                     the  Act.

          Exhibit 7. A copy of the latest report of condition of the trustee
                     published pursuant to law or the requirements of its
                     supervising or examining authority.**

          Exhibit 8. Not applicable.

          Exhibit 9. Not applicable.

          *    Incorporated by reference to exhibit number 25 filed with
               registration statement number 33-66026.

          **   Incorporated by reference to exhibit number 25 filed with
               registration statement number 333-32992.


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                                    SIGNATURE

Pursuant to the requirements of the Trust Indenture Act of 1939, as amended, the
trustee, Norwest Bank Minnesota, National Association, a national banking
association organized and existing under the laws of the United States of
America, has duly caused this statement of eligibility to be signed on its
behalf by the undersigned, thereunto duly authorized, all in the City of
Minneapolis and State of Minnesota on the 25th day of May 2000.

                             NORWEST BANK MINNESOTA,
                             NATIONAL ASSOCIATION

                              /s/ Jane Y. Schweiger
                         --------------------------------

                             Jane Y. Schweiger
                             Corporate Trust Officer


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                                    EXHIBIT 6

May 25, 2000

Securities and Exchange Commission
Washington, D.C.  20549

Gentlemen:

In accordance with Section 321(b) of the Trust Indenture Act of 1939, as
amended, the undersigned hereby consents that reports of examination of the
undersigned made by Federal, State, Territorial, or District authorities
authorized to make such examination may be furnished by such authorities to the
Securities and Exchange Commission upon its request therefor.

                                            Very truly yours,

                                            NORWEST BANK MINNESOTA,
                                            NATIONAL ASSOCIATION

                                            /s/ JANE Y. SCHWEIGER
                                            ---------------------
                                            Jane Y. Schweiger
                                            Corporate Trust Officer


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