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EXHIBIT 12.1
CV Therapeutics, Inc.
Computation of Ratios of Earnings to Fixed Charges
(in thousands, except ratio)
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Three months
ended
Years ended December 31, March 31,
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1995 1996 1997 1998 1999 2000
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<S> <C> <C> <C> <C> <C> <C>
Net loss $(16,724) $(10,365) $(11,325) $(12,602) $(23,122) $ (7,083)
Add: Fixed charges 1,280 1,553 1,341 1,223 1,367 1,011
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Earnings as defined $(15,444) $ (8,812) $ (9,984) $(11,379) $(21,755) $ (6,072)
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Estimated interest component of rent $ 397 $ 442 $ 466 $ 464 $ 475 $ 117
Interest expense (1) 883 1,111 875 759 892 894
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Total fixed charges $ 1,280 $ 1,553 $ 1,341 $ 1,223 $ 1,367 $ 1,011
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Ratio (2) (2) (2) (2) (2) (2)
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(1) Includes amortization of debt issuance costs
(2) Earnings (as defined) for the period were insufficient to cover fixed
charges by an amount equal to the net loss for the period.