CYCLODEXTRIN TECHNOLOGIES DEVELOPMENT INC
8-K, 1997-12-29
MEDICINAL CHEMICALS & BOTANICAL PRODUCTS
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                       SECURITIES AND EXCHANGE COMMISSION
                            Washington, D. C.   20549

                                   FORM 8-K

                Current Report Pursuant to Section 13 or 15(d)
                    of The Securities Exchange Act of 1934


  Date of Report: December 23, 1997      Commission file number:  0-24930


                   CYCLODEXTRIN TECHNOLOGIES DEVELOPMENT, INC.
             (Exact name of registrant as specified in its charter)




          FLORIDA                                             59-3029743
(State or other jurisdiction                                 (IRS Employer 
of incorporation or organization)                          Identification No.)



       3713 SW 42nd Avenue, Suite 3, Gainesville, Florida, 32608-6581
  (Address of principal executive offices)                      (Zip Code)


Registrant's telephone number, including area code:   352-375-6822
<PAGE>
Item 4 - Changes in Registrant's Certifying Accountant

(a) On December 23, 1997, Registrant engaged the accounting firm of James Moore
& Co., C.P.A., as independent accountants for the Registrant for 1997.  The 
work of Davis, Monk & Co., C.P.A.,  was terminated on December 23, 1997.  The 
termination of Davis, Monk & Co. and the engagement of James Moore & Co. was 
approved by Registrant's Board of Directors.

(b) During the period of engagement of Davis, Monk & Co., which has been since 
December 5, 1996, there have been no disagreements between them and Registrant 
on any matter of accounting principles or practices, financial statement 
disclosure, auditing scope or procedure, or reportable events.

(c) Davis, Monk & Co.'s reports on the financial statements for its period of 
engagement by Registrant contained no adverse opinion or disclaimer of opinion 
and was not qualified or modified as to uncertainty, audit scope or accounting 
principles.

(d) The Registrant requested that Davis, Monk & Co. furnish it with a 
letter addressed to the Securities and Exchange Commission stating whether or 
not it agrees with the statements made by the Registrant in response to this 
Item 4 and if not, stating the respects in which it does not agree.  Registrant
delivered a copy of this Form 8-K Report to Davis, Monk & Co. on December 23, 
1997.  By letter dated December 26, 1997, Davis, Monk & Co. stated that it 
agreed with the information contained in this report on Form 8-K.  The 
Registrant herewith files a copy of such letter as an exhibit to this report

<PAGE>
Item 14.  Exhibits, Financial Statement Schedules, and Reports on Form 8-K 
 
Exhibit     Description                                                  Page 



(1) Underwriting agreement                                               None

(2) Plan of acquisition, reorganization, 
    arrangement, liquidation or succession                               None

(4) Instruments defining the rights of 
    security holders, including debentures                               None

(16) Letter re change in certifying accountant                             5

(17) Letter re director resignation                                      None

(21) Other documents or statements to security holders                   None
 
(24) Consents of experts and counsel                                     None

(25) Power of attorney                                                   None

(28) Additional exhibits                                                 None


<PAGE>
SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act of 1934, the 
registrant has duly caused this report to be signed on its behalf by the 
undersigned thereunto duly authorized.
 
 
                         CYCLODEXTRIN TECHNOLOGIES
                            DEVELOPMENT, INC.
                             (Registrant)


DATED: December 23, 1997

                         By: _________/S/__________________________
                            C. E. RICK STRATTAN, President, Chief
                            Executive Officer, and Chief Financial 
                                Officer





                 [DAVIS MONK & COMPANY LETTERHEAD]

                                                     December 26, 1997

Mr. C.E. "Rick" Strattan
Cyclodextrin Technologies Development, Inc.
3713 S.W. 42 Avenue, Suite 3
Gainesville, Florida 32608-6518

Dear Mr. Strattan:

We have reviewed the form 8-K provided to us on December 23, 1997 and
agree with the information contained therein.


                                       /S/ Davis, Monk & Company
                                       DAVIS, MONK & COMPANY
                                    CERTIFIED PUBLIC ACCOUNTANTS
                                       & BUSINESS CONSULTANTS

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