MEDPLUS INC /OH/
11-K, 1998-07-01
COMPUTER PERIPHERAL EQUIPMENT, NEC
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          U. S. SECURITIES AND EXCHANGE COMMISSION
                  Washington, D.C.  20549

                         FORM 11-K

                        (Mark One)

    [X]     ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE
            SECURITIES EXCHANGE ACT OF 1934

            For the fiscal year ended   December 31, 1997

    [ ]     TRANSITION REPORT PURSUANT TO SECTION 15(d) OF THE
            SECURITIES EXCHANGE ACT OF 1934


For the transition period from  ______________ to ______________


                   MEDPLUS, INC. 401(K) PLAN
                   (Full title of the plan)

                          MEDPLUS, INC.
  (Name of issuer of the securities held pursuant to the plan)

   8805 Governor's Hill Drive, Suite 100, Cincinnati OH 45249
            (Address of principal executive offices)



                         MedPlus, Inc. 401k Plan

                               December 31, 1997

                               Table of Contents



                                                             Page
Independent Auditors' Report                                   1     

Statements of Assets Available for Plan Benefits, with Fund 
  Information - December 31, 1997                              2 

Statements of Assets Available for Plan Benefits, with Fund 
     Information - December 31, 1996 (unaudited)               3

Statements of Changes in Assets Available for Plan Benefits, 
     with Fund Information - for the year ended 
     December 31, 1997                                         4

Notes to Financial Statements                              5 - 9

     
Schedules

1 Item 27a, Schedule of Assets Held for Investment 
  Purposes - December 31, 1997                                10

2 Item 27d, Schedule of Reportable Transactions -
  December 31, 1997                                           11


     





                         Independent Auditors' Report


The Trustees
MedPlus, Inc. 401k Plan

We have audited the accompanying statement of assets available for 
plan benefits of the MedPlus, Inc. 401k Plan as of December 31, 
1997, and the related statement of changes in assets available for 
plan benefits for the year then ended. These financial statements 
are the responsibility of the Plan's management. Our 
responsibility is to express an opinion on these financial 
statements based on our audit. We have not audited the 
accompanying statement of assets available for plan benefits as of 
December 31, 1996.

We conducted our audit in accordance with generally accepted 
auditing standards. Those standards require that we plan and 
perform the audit to obtain reasonable assurance about whether the 
financial statements are free of material misstatement. An audit 
includes examining, on a test basis, evidence supporting the 
amounts and disclosures in the financial statements. An audit also 
includes assessing the accounting principles used and significant 
estimates made by management, as well as evaluating the overall 
financial statement presentation. We believe that our audit 
provides a reasonable basis for our opinion.

In our opinion, the financial statements referred to above present 
fairly, in all material respects, the assets available for plan 
benefits of the MedPlus, Inc. 401k Plan as of December 31, 1997, 
and the changes in assets available for plan benefits for the year 
then ended in conformity with generally accepted accounting 
principles.

Our audit was performed for the purpose of forming an opinion on 
the basic financial statements taken as a whole. The supplemental 
schedules of Assets Held for Investment Purposes and Reportable 
Transactions are presented for the purpose of additional analysis 
and are not a required part of the basic financial statements, but 
are supplementary information required by the Department of 
Labor's Rules and Regulations for Reporting and Disclosure under 
the Employee Retirement Income Security Act of 1974. The fund 
information in the statements of assets available for benefits and 
the statements of changes in assets available for plan benefits is 
presented for purposes of additional analysis rather than to 
present the assets available for plan benefits and changes in plan 
assets available for plan benefits of each fund. The supplemental 
schedules and fund information have been subjected to the auditing 
procedures applied in the audits of the basic financial statements 
and, in our opinion, are fairly stated in all material respects in 
relation to the basic financial statements taken as a whole.




June 24, 1998


(1)  Description of Plan

The following description of the MedPlus, Inc. 401k Plan (the 
Plan) provides only general information. Participants should refer 
to the Plan agreement for a more complete description of the 
Plan's provisions.     

     (a)  General

          The Plan is a defined contribution plan covering all 
employee classifications except those employees leased by MedPlus, 
Inc. (The Company). The Plan is subject to the provisions of the 
Employee Retirement Income Security Act of 1974 (ERISA). Employees 
are eligible for participation in the Plan after attainment of age 
21.

     (b)  Contributions
     
          A participant may make contributions to the Plan by 
authorizing a deferral of pretax annual compensation, as defined 
in the Plan, up to a maximum of 15%, subject to limitations of the 
Internal Revenue Code. The Company may provide a matching 
contribution equal to such of the participants contribution as 
determined by the employer in its discretion for each Plan year. 
An additional discretionary contribution may also be made by the 
Company. Both the matching contribution and the additional 
discretionary contribution are non-participant directed.
          
     (c)  Participant Accounts

          Each participant's account is credited with the 
participant's contribution and allocation of the Company's 
contribution and Plan earnings. Earnings and gains and losses of 
each investment fund are allocated among the accounts of all 
participants in each fund in the ratio each participant account 
bears to the total account balance. Participants have the ability 
to self-direct the investments of funds allocated to their 
accounts.

     (d)  Vesting

          Participants are immediately vested in their voluntary 
contributions plus actual earnings thereon. Participants become 
20% vested in Company contributions after two years of service. 
Thereafter, participants become vested at a rate of 20% per year 
of service and become fully vested after six years of service. 

     (e)  Participant Loans Receivable

          Participants may borrow from their accounts not less 
than $1,000 and not more than 50% of their vested balance for the 
following hardships: 

          - Purchase of primary  residence
          - Foreclosure or eviction from primary residence
          - College tuition for participant or dependents
          - Medical expenses incurred from prolonged illness, 
disability, or death in immediate family.
          
          Loan terms provide for  repayment over a period not to 
exceed five years. The loans are secured by the balances in the 
participants' accounts and bear interest at 2% over the prime 
interest rate.   Principal and interest amounts are paid ratably 
through payroll deductions. There have been no loans since 
inception of the Plan.

     (f)  Payment of Benefits

          Under the terms of the Plan, upon termination of 
employment a participant's account is distributed upon written 
request of the participant. A participant or participant's estate 
is entitled to receive 100% of the related account balance if 
termination results from reaching normal retirement age, death or 
permanent disability. As of December 31, 1997 there were no 
amounts allocated to accounts of persons who have withdrawn from 
participation in the earnings and operations of the Plan.
 
     (g)  Forfeitures

          Forfeitures of Company contributions by terminated 
participants are used to reduce Company contributions. As of 
December 31, 1997, forfeitures of approximately $7,200 are 
available to reduce future employer contributions.

     (h)  Investment Options

          Upon enrollment in the Plan, a participant may direct 
employee deferred contributions to any of the following eight 
investment options as of December 31, 1997:

          -  Money Market Fund

             Funds are invested in a portfolio of fixed income 
securities, including U.S. Treasuries and related repurchase 
agreements and obligations of U.S. Government Agencies and 
Instrumentalities.


          -  Diversified Income Fund

             Funds are invested in a portfolio of three fixed 
income sectors, which are comprised of U.S. Government securities, 
lower rated, high-yield debt securities, and international 
investing.

          -  Balance Fund

             Funds are invested in a portfolio of stocks and 
bonds.

          -  Investors Fund

             Funds are invested primarily in quality, long-term 
growth stocks.

          -  Global Growth Fund

             Funds are invested in a portfolio of common stocks 
traded in securities markets, located in foreign countries and in 
the United States.

          -  Vista Fund

             Funds are invested in a portfolio of stocks of 
medium-sized growth companies.

          -  New Opportunities Fund

             Funds are invested in dynamic, rapidly growing 
sectors of the economy.

          -  MedPlus Stock

             Funds are invested in the Company's common stock. 

(2)  Summary of Significant Accounting Policies

     (a)  Basis of Presentation

          The accompanying financial statements of the Plan have 
been prepared on the accrual basis of accounting.

     (b)  Investments

          Money market accounts are valued at cost which 
approximates fair value. All other investments are recorded at 
fair value based on quotations obtained from national securities 
exchanges. Purchases and sales of investments are recorded on a 
trade-date basis. Gains or losses on the sales of investments are 
calculated on the specific identification method.

     (c)  Expenses

          All administrative and investment expenses incurred by 
the Plan have been paid by the Company.

     (d)  Use of Estimates

          The Plan administrator has made a number of estimates 
and assumptions relating to the preparation of these financial 
statements in accordance with generally accepted accounting 
principles. Actual results could differ from those estimates and 
assumptions.

(3)  Investments

     Prior to January 1, 1997, the custodian of the Plan was 
Merrill Lynch. Effective January 1, 1997, Smith Barney Shearson 
(now Salomon Smith Barney) assumed the role as custodian for the 
Plan.  In this capacity, the custodian is to receive and invest 
the contributions made by the participants and the employer, the 
interest, dividends, and other income earned on investments and to 
pay benefits and expenses as provided by the Plan.

     The following table presents the fair values of investments 
at December 31, 1997 that represent five percent or more of the 
Plan's assets:

                Balance Fund                $ 126,633
                Investors Fund                238,849
                Vista Fund                    246,330
                Global Growth Fund             94,314
                New Opportunities Fund        381,735
                MedPlus Stock                 155,892

     During 1997, the Plan's investments (including investments 
bought, sold, and held during the year) appreciated in value as 
follows:

                Mutual funds                $ 129,024
                Common stock                    4,516
                                            _________
                Net change in fair value    $ 133,540
                                            _________
                                            _________
     
(4)  Employer Contributions

     At December 31, 1997, there was a receivable from the Company 
consisting of the matching and the additional discretionary 
contributions for the 1997 Plan Year.  The Company elected to make 
both these contributions in MedPlus, Inc. Common Stock.

(5)  Plan Termination

     Although  it has not expressed any intent to do so, the 
Company has the right under the Plan to discontinue its 
contributions at any time and to terminate the Plan subject to the 
provisions of ERISA. In the event of  Plan termination, 
participants will become 100% vested in their accounts.

(6)  Tax Status

     The Internal Revenue Service issued its latest determination 
letter on August 2, 1993, which stated that the Plan and its 
underlying trust qualify under the applicable provisions of the 
Internal Revenue Code and, therefore, are exempt from Federal 
income tax. In the opinion of the Plan trustee and the Company, 
the Plan and its underlying trust have operated within the terms 
of the Plan and remain qualified under the applicable provisions 
of the Internal Revenue Cod

<TABLE>                                      MedPlus Inc. 401(k) Plan 
<CAPTION> 
                                                Statement of Assets 
                            Available for Plan Benefits, with Fund Information 
 
                                            Year ended December 31, 1997 
 
 
 
                                                              Fund Information                       
                            ________________________________________________________________________________
<S>                             Smith    Putnam                                   Putnam
                                Barney  Diversi-         Putnam           Putnam    New 
                                Money     fied   Putnam  Invest-  Putnam  Global  Opportu- MedPlus
                                Market   Income  Balance  tors    Vista   Growth  nities   Stock    Total
                               _______  _______  _______ _______ _______  _______ _______  _______ _________
Assets:                        <C>      <C>      <C>     <C>     <C>      <C>     <C>      <C>     <C> 
  Investments, at fair value 
  (note 3): 
    Interest-bearing cash      $50,985      -      -        -       -        -       -        -       50,985
    Mutual funds                  -     35,113   126,633 238,849 246,330  94,314  381,735     -    1,122,974
    Common stock                  -         -      -        -       -        -       -     155,892   155,892
                               _______  _______  _______ _______ _______  _______ _______  _______ _________
      Total investments         50,985  35,113   126,633 238,849 246,330  94,314  381,735  155,892 1,329,851 
 
Receivables:                                                     
  Participant contributions      6,164     461     2,179   4,181   5,657   2,816    5,776   1,811     29,045
  Employer contributions 
    (note 4):                     -         -      -         -       -       -       -     213,495   213,495
                               _______  _______  _______ _______ _______  _______ _______  _______ _________
Assets available for plan                                           
     benefits                  $57,149  35,574   128,812 243,030 251,987  97,130  387,511  371,198 1,572,391
                               _______  _______  _______ _______ _______  _______ _______  _______ _________
                               _______  _______  _______ _______ _______  _______ _______  _______ _________ 

See accompanying notes to financial statements.       
</TABLE>

<TABLE>
<CAPTION>                                MedPlus, Inc. 401(k) Plan                                 
                                 
                   Statement of Assets Available for Plan Benefits, with Fund Information 
                                 
                                         Year ended December 31, 1996
                                                 (Unaudited)                              
                                 
                                 
                                                   Fund Information       
                               ________________________________________________________   
                                Pimco      Pimco       Pimco                                    
                                Money       U.S.       Equity      Pimco       MedPlus  
                                Market    Government   Income      Target       Stock    Total
                               _________  __________   _________   _________   ________  _______
<S>                            <C>        <C>          <C>         <C>         <C>       <C>
Assets:                                 
  Investments, at fair value: 
    Interest-bearing cash      $ 47,276       -           -           -           -       47,276 
    Mutual funds                  -           -        196,809     322,005        -      518,814 
    Government securities         -         21,021        -           -           -       21,021 
    Common stocks                 -           -           -           -         48,783    48,783 
                               _________  __________   _________   _________   _________ _______                                 
      Total investments          47,276     21,021     196,809     322,005      48,783   635,894                                  
Receivables -                                  
  Participant contributions       1,062      1,048       4,954      10,942         784    18,790 
                               _________  __________   _________   _________   _________ _______

    Assets available for
     plan benefits               48,338     22,069     201,763     332,947      49,567   654,684 
                               _________  __________   _________   _________   _________ _______
                               _________  __________   _________   _________   _________ _______                                 

See accompanying notes to financial statements.                                             
</TABLE>                                    

<TABLE>
<CAPTION>
                                           MedPlus Inc. 401(k) Plan
                              Statement of Changes in Assets Available for
                                      Plan Benefits, with Fund Information 
                                                        
                                        Year ended December 31, 1997     
                                                         
                                                            Merrill Lynch Funds 
                                        __________________________________________________________
                                         Pimco   
                                         Funds 
                                         Money          US       Equity                   MedPlus
                                         Market     Government   Income      Target        Stock
                                       _________     __________  _________   _________   _________ 
<S>                                    <C>           <C>          <C>        <C>         <C>
Assets available for plan benefits, 
  December 31, 1996                    $ 48,338      22,069       201,763     332,947      49,567
Contributions: 
  Employer                                  -           -           -           -           -
  Employee                                  -           -           -           -           -  
  Rollovers from other benefit plans        -           -           -           -           - 
Investment income:
  Interest and dividends                    -           -           -           -           -
Net appreciation (depreciation) in 
  fair value of investments 
  (note 3)                                  -           -           -           -           -
Benefits paid to participants               -           -           -           -           -
Interfund transfers, net                (48,338)    (22,069)     (201,763)   (332,947)    (49,567) 
                                       _________     __________  _________   _________   _________
Assets available for plan benefits, 
     December 31, 1997                 $    -           -           -           -           - 
                                       _________     __________  _________   _________   _________
                                       _________     __________  _________   _________   _________

See accompanying notes to financial statements.                                                        
</TABLE


</TABLE>
<TABLE>                                           MedPlus Inc. 401(k) Plan  
<CAPTION>                                                        
                              Statement of Changes in Assets Available for Plan
                                               Benefits, with Fund Information
                                                 Year ended December 31, 1997 
                                                        
                                                        Smith Barney Funds   
                          __________________________________________________________________________________
<S>                       Putnam   Putnam                                       Putnam
                          Funds    Diversi-          Putnam            Putnam   New
                          Money    fied     Putnam   Invest-  Putnam   Global   Opportu-  MedPlus
                          Market   Income   Balance  ors      Vista    Growth   nities    Stock      Total
                          _______  _______  _______  _______  _______  _______  _______   ________  ________
                          <C>      <C>      <C>      <C>      <C>      <C>      <C>       <C>        <C>
Assets available for
  plan benefits,
  December 31, 1996          -        -        -        -        -        -        -         -      654,684 
Contributions: 
  Employer                   -        -        -        -        -        -        -       213,495  213,495 
  Employee                 13,908   11,368   33,177   72,689  106,315   50,129   166,294    77,978  531,858 
  Rollovers from other
    benefit plans          13,482     -      28,555   27,735   40,526    1,626    39,174    29,104  180,202 
Investment income:              
  Interest and dividends    2,707    1,861    6,101    3,271    2,196    6,635     1,848       632   25,251 
Net appreciation
 (depreciation) in fair
 value of investments 
 (note 3)                    -         533    8,925   40,176   31,061     (844)   49,173     4,516  133,540 
Benefits paid to 
  participants            (31,264) (13,597) (20,124) (36,217) (28,328)  (4,306)  (26,184)   (6,619)(166,639)
Interfund transfers, net   58,316   35,409   72,178  135,376  100,217   43,890   157,206    52,092     -  
                          _______  _______  _______  _______  _______  _______  _______   ________  ________
Assets available for 
   plan benefits,              
   December 31, 1997      $57,149   35,574  128,812  243,030  251,987   97,130  387,511    371,198 1,572,391
                          _______  _______  _______  _______  _______  _______  _______   ________  ________
            _______  _______  _______  _______  _______  _______  _______   ________  ________


See accompanying notes to financial statements. 

</TABLE>



<TABLE>                                                                                   Schedule 1
<CAPTION>             
                                    MedPlus, Inc. 401(k) Plan                      
                  Item 27a, Schedule of Assets Held for Investment Purposes                      
                                          December 31, 1997                      
                                                                                               Fair
          Issuer                             Description                      Cost            value
___________________________       ________________________________          _________       _________            
<S>                               <C>                                    <C>               <C>
Money Market Fund        
       
Smith Barney                      Money market fund (50,985 units)       $     50,985          50,985 
                                                                            _________       _________
Putnam Mutual Funds        
        
Diversified Income Fund           Mutual fund (2,791 units)                    34,573          35,113 
Balance Fund                      Mutual fund (7,039 units)                   123,798         126,633 
Investors Fund                    Mutual fund (21,250 units)                  222,476         238,849 
Vista Fund                        Mutual fund (20,752 units)                  235,963         246,330 
Global Growth Fund                Mutual fund (9,469 units)                   106,215          94,314 
New Opportunities Fund            Mutual fund (7,770 units)                   337,364         381,735 
                                                                            _________       _________

  Total Putnam Mutual Funds                                                 1,060,389       1,122,974 
                                                                            _________       _________
Common Stock                                                  
                                                  
*MedPlus, Inc.                     Common stock (21,136 shares)               157,991         155,892 
                                                                             _________       _________

  Total Investments                                                      $  1,269,365       1,329,851 
                                                                             _________       _________
 *Denotes party-in-interest.                                                 _________       _________
</TABLE>


<TABLE>                                                                                     Schedule 2
<CAPTION>         
                                         MedPlus, Inc. 401(k) Plan        
                  
                               Item 27d, Schedule of Reportable Transactions                  
                  
                                        Year ended December 31, 1997                  
                  
                  
                                                                                       Cost          
        Identity of                     Description       Purchase      Selling      of asset       Net
       party involved                  of investment       price         price         sold         gain
______________________________       _________________    __________   _________     _________    _________  
<S>                                  <C>                  <C>          <C>           <C>           <C>     
Purchases                  
                  
Putnam Diversified Income Fund       Mutual fund          $   46,066          -             -             -  
Putnam Balance Fund                  Mutual fund             139,570          -             -             -  
Putnam Investors Fund                Mutual fund             247,894          -             -             -  
Putnam Vista Fund                    Mutual fund             272,342          -             -             -  
Putnam Global Growth Fund            Mutual fund             107,603          -             -             -  
Putnam New Opportunities Fund        Mutual fund             343,973          -             -             -  
MedPlus Stock                        Common stock            165,785          -             -             -  
Smith Barney Money Market Fund       Money market fund       902,815          -             -             -    
                  
                  
Sales                  
                  
Putnam Vista Fund                    Mutual fund                -           39,495        36,379         
3,117 
                  
Smith Barney Money Market Fund       Money market fund          -          947,554       947,554          -  
                                                  
                                                  
                                                  
</TABLE>                                          
                                                  


SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act 
of 1934, the trustees have duly caused this annual report to be 
signed on its behalf by the undersigned hereunto duly authorized.
     
MEDPLUS, INC 401(K) PLAN


Signature                                   Date


/s/ Amy J. Seltz                          June 30, 1998
Amy J. Seltz                    
                    
/s/ Daniel A. Silber                      June 30, 1998
Daniel A. Silber                                        
Vice President of Finance 
and Chief Financial Officer                            














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