S R ONE LTD
SC 13D/A, 2000-10-13
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<PAGE>   1
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                  SCHEDULE 13D


                    UNDER THE SECURITIES EXCHANGE ACT OF 1934

                                (Amendment No. 1)


                               Corixa Corporation
--------------------------------------------------------------------------------
                                (Name of Issuer)


                          Common Stock, $.001 Par Value
--------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                    21887F100
--------------------------------------------------------------------------------
                                 (CUSIP Number)


                Donald F. Parman, SmithKline Beecham Corporation
                   One Franklin Plaza, Philadelphia, PA 19102
                             Telephone 215-751-7633
--------------------------------------------------------------------------------
           (Name, Address and Telephone Number of Person Authorized to
                       Receive Notices and Communications)


                                 October 6, 1999
--------------------------------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)


If the filing person has previously filed a statement on Schedule 13G to report
the acquisition which is the subject of this Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box / /.

Check the following box if a fee is being paid with the statement / /.
(A fee is not required only if the reporting person: (1) has a previous
statement on file reporting beneficial ownership of more than five percent of
the class of securities described in Item 1; and (2) has filed no amendment
subsequent thereto reporting beneficial ownership of five percent or less of
such class.) (See Rule 13d-7.)

Note: Six copies of this statement, including all exhibits, should be filed with
the Commission. See Rule 13d-1(a) for other parties to whom copies are to be
sent.

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

This Amendment No. 1 amends and supplements the Statement of Schedule 13D
electronically filed with the Securities and Exchange Commission (the
"Commission") on February 5, 1999 (the "Initial Statement").

The undersigned hereby amends and supplements Item 5 of the Initial Statement to
include the following information (capitalized terms used herein without
definition shall have the same meaning as set forth in the Initial Statement.
<PAGE>   2
                                  SCHEDULE 13D

CUSIP NO. 21887F100                                            PAGE 2 OF 7 PAGES

--------------------------------------------------------------------------------

1   NAME OF REPORTING PERSON
    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

        S.R. One, Limited
        23-1729901
-------------------------------------------------------------------------------
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                         (a) /x/
                                                                         (b) / /
--------------------------------------------------------------------------------
3   SEC USE ONLY


--------------------------------------------------------------------------------
4   SOURCE OF FUNDS*

        WC
--------------------------------------------------------------------------------
5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
    TO ITEMS 2(D) OR 2(E)                                                    / /

--------------------------------------------------------------------------------
6   CITIZENSHIP OR PLACE OF ORGANIZATION


        Pennsylvania Business Trust
--------------------------------------------------------------------------------
                7   SOLE VOTING POWER
  NUMBER OF
   SHARES               530,427
BENEFICIALLY   -----------------------------------------------------------------
  OWNED BY      8   SHARED VOTING POWER
   EACH
 REPORTING
  PERSON       -----------------------------------------------------------------
   WITH         9   SOLE DISPOSITIVE POWER

                        530,427
              -----------------------------------------------------------------
               10   SHARED DISPOSITIVE POWER


--------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        530,427
--------------------------------------------------------------------------------
12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
     CERTAIN SHARES*                                                         / /

--------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

        2.5%
--------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON*

        CO
--------------------------------------------------------------------------------
<PAGE>   3
                                  SCHEDULE 13D

CUSIP NO. 21887F100                                            PAGE 3 OF 7 PAGES

--------------------------------------------------------------------------------

1   NAME OF REPORTING PERSON
    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

        SmithKline Beecham plc
        98-0101920
-------------------------------------------------------------------------------
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                         (a) /x/
                                                                         (b) / /
--------------------------------------------------------------------------------
3   SEC USE ONLY


--------------------------------------------------------------------------------
4   SOURCE OF FUNDS*

        WC
--------------------------------------------------------------------------------
5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
    TO ITEMS 2(D) OR 2(E)                                                    / /

--------------------------------------------------------------------------------
6   CITIZENSHIP OR PLACE OF ORGANIZATION


        England
--------------------------------------------------------------------------------
                7   SOLE VOTING POWER
  NUMBER OF
   SHARES               427,807
BENEFICIALLY   -----------------------------------------------------------------
  OWNED BY      8   SHARED VOTING POWER
   EACH
 REPORTING
  PERSON       -----------------------------------------------------------------
   WITH         9   SOLE DISPOSITIVE POWER

                        427,807
               -----------------------------------------------------------------
               10   SHARED DISPOSITIVE POWER


--------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        427,807
--------------------------------------------------------------------------------
12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
     CERTAIN SHARES*                                                         / /

--------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

        2.0%
--------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON*

        CO
--------------------------------------------------------------------------------
                     *SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>   4
                                  SCHEDULE 13D

CUSIP NO. 21887F100                                            PAGE 4 OF 7 PAGES

--------------------------------------------------------------------------------
1   NAME OF REPORTING PERSON
    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

        SmithKline Beecham Biologicals Manufacturing s.a.

-------------------------------------------------------------------------------
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                         (a) /x/
                                                                         (b) / /
--------------------------------------------------------------------------------
3   SEC USE ONLY


--------------------------------------------------------------------------------
4   SOURCE OF FUNDS*

        WC
--------------------------------------------------------------------------------
5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
    TO ITEMS 2(D) OR 2(E)                                                    / /

--------------------------------------------------------------------------------
6   CITIZENSHIP OR PLACE OF ORGANIZATION


        Belgium
--------------------------------------------------------------------------------
                7   SOLE VOTING POWER
  NUMBER OF
   SHARES               185,922
BENEFICIALLY   -----------------------------------------------------------------
  OWNED BY      8   SHARED VOTING POWER
   EACH
 REPORTING
  PERSON       -----------------------------------------------------------------
   WITH         9   SOLE DISPOSITIVE POWER

                                185,922
               -----------------------------------------------------------------
               10   SHARED DISPOSITIVE POWER


--------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        185,922
--------------------------------------------------------------------------------
12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
     CERTAIN SHARES*                                                         / /

--------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

        .9%
--------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON*

        CO
--------------------------------------------------------------------------------
<PAGE>   5
                                                               PAGE 5 OF 7 PAGES

Item 1.  Security and Issuer.


Item 2.  Identity and Background.

                (a) SmithKline Beecham Biologicals Manufacturing s.a. (SBBM), a
company organized under the laws of Belgium, engages in commercial, industrial
and financial activities relating to real and personal property for SmithKline
Beecham's worldwide vaccines business, SmithKline Beecham Biologicals.

                         Collectively, SRO, SBplc and SBBM are sometimes
referred to as the "Group".

                (b) The principal business address for SBBM is:

                         Rue de l'Institut 89
                         B-1330 Rixensart
                         BELGIUM


                (c) Information concerning the Group is set forth in response to
Item 2(a) above.

                (d) During the last five years, the Group has not been convicted
in a criminal proceeding, excluding traffic violations or similar misdemeanors.

                (e) During the last five years the Group was not a party to a
civil proceeding of a judicial or administrative body of competent jurisdiction
and as a result thereof subject to a judgment, decree or final order enjoining
future violations of, or prohibiting or mandating activities subject to Federal
or State securities laws or finding any violation with respect to such laws.

                (f) Not applicable.
<PAGE>   6
                                                               PAGE 6 OF 7 PAGES

Item 3.  Source and Amount of Funds or Other Consideration.


Item 4.  Purpose of Transaction.

         The Group intends to review from time to time the business affairs and
financial position of the Issuer. Based on such evaluation and review, as well
as general economic and industry conditions existing at the time and the Group's
own financial plans, the Group may consider from time to time various
alternative courses of action. Such actions may include the acquisition of
additional shares through open market purchases, privately negotiated
transactions or otherwise. Alternatively, such actions may involve the sale of
all or a portion of the shares in the open market, in privately negotiated
transactions, through public offering or otherwise. All of the securities
acquired have been purchases for investment purposes.


Item 5.  Interest in Securities of the Issuer.

                  (a)  Amount and Percent Beneficially Owned

<TABLE>
<CAPTION>
                       Registered Name         No. of Shares      Percent
<S>                                            <C>                <C>
                       SRO                       505,050
                       SRO                        25,377 *        2.5%
                       SBplc                     427,807          2.0%
                       SBBM                      185,922 *        0.9%
                                               ---------          ----
                                               1,144,156          5.4%
</TABLE>

*On October 6, 1999, Ribi Immunochem Research Inc. (Ribi) merged into Issuer.
SRO and SBBM received an aggregate amount of 211,299 shares of Issuer's Common
stock in exchange for their Ribi shares as a result of this merger.



Item 6.  Contracts, Arrangements, Understandings or
         Relationship With respect to Securities of the Issuer.


Item 7.  Materials to be Filed as Exhibits.

         Exhibit 1.  Joint Filing Agreement dated as of October 4, 2000



                                    SIGNATURE

                After reasonable inquiry and to the best of my knowledge and
belief, the undersigned certifies that the information set forth in the
Statement is true, correct and complete.

DATED:  October 11, 2000                        S.R. ONE, LIMITED



                                                By: /s/
                                                     Donald F. Parman
                                                     Vice President
                                                     and Secretary
<PAGE>   7
                                                               PAGE 7 OF 7 PAGES

                                    EXHIBIT 1

        The undersigned hereby agree, pursuant to Rule 13d-1(f)(1) under Section
13(d) of the Securities Exchange Act of 1934, as amended, that (1) they shall
cause a single Schedule 13D to be filed on behalf of each party in respect
of their ownership interests in the Common Stock of Corixa Corporation and (2)
S.R. One, Limited shall be authorized to sign said Schedule 13D and any
amendments thereto on behalf of each member of the Group.


                                           S.R. ONE, LIMITED


                                           By: /s/
                                                Donald F. Parman
                                                Vice President
                                                and Secretary

                                           SMITHKLINE BEECHAM plc


                                           By: /s/
                                           Name: S. Wilbraham
                                           Title: Assistant
                                                  Sectretary

                                           SMITHKLINE BEECHAM BIOLOGICALS
                                           MANUFACTURING s.a.


                                           By: /s/
                                           Name: Jean-Pierre Suin
                                           Title: Vice President Director
                                                  Finances/I.R.
DATED: October 4, 2000                            Management Services


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