SANGUINE CORP
10QSB, 1996-06-10
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>
                 U. S. Securities and Exchange Commission
                         Washington, D. C.  20549


                                FORM 10-QSB


[X]  QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES
     EXCHANGE ACT OF 1934

     For the quarterly period ended March 31, 1996

[ ]  TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES
     EXCHANGE ACT OF 1934 

     For the transition period from                to 
                                    --------------    ---------------

                                     
                       Commission File No. 0-24480


                           SANGUINE CORPORATION    
              (Name of Small Business Issuer in its Charter)


           NEVADA                                        95-4347608 
           ------                                        ----------    
   (State or Other Jurisdiction of                 (I.R.S. Employer I.D. No.)
    incorporation or organization)

                        101 East Green Street, #11
                        Pasadena, California  91105    
                        ---------------------------
                 (Address of Principal Executive Offices)

                Issuer's Telephone Number:  (818) 405-0079


Indicate by check mark whether the Registrant (1) has filed all reports
required to be filed by Sections 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
Registrant was required to file such reports), and (2) has been
subject to such filing requirements for the past 90 days.

(1)  Yes  X    No                  (2)  Yes  X    No 
         ---     ---                        ---     ---

















<PAGE>
             APPLICABLE ONLY TO ISSUERS INVOLVED IN BANKRUPTCY
                PROCEEDINGS DURING THE PRECEDING FIVE YEARS

                              Not applicable.


                   APPLICABLE ONLY TO CORPORATE ISSUERS

Indicate the number of shares outstanding of each of the Registrant's classes
of common stock, as of the latest practicable date:

                               June 4, 1996

                                19,562,859
                                ----------



                      PART I - FINANCIAL INFORMATION


Item 1.   Financial Statements.

          The Financial Statements of the Registrant required to be filed with
this 10-QSB Quarterly Report were prepared by management, and commence on the
following page, together with Related Notes.  In the opinion of management,
the Financial Statements fairly present the financial condition of the
Registrant.



































<PAGE>
                           SANGUINE CORPORATION
                       (A Development Stage Company)
                               Balance Sheet
             March 31, 1996 (Unaudited) and December 31, 1995
<TABLE>
<CAPTION>
                                        Unaudited 
                                              1996                1995 
                                              ----                ----
                                  ASSETS
<S>                                 <C>                 <C>
Current Assets
- --------------
     Cash                           $        1,015      $           712 

Property & Equipment
- --------------------
     Furniture                               2,614                2,844     

Other Assets
- ------------
     Refundable Loan Commitment
      Fee (See Note #10)                    10,000               10,000 
                                            ------               ------

     TOTAL ASSETS                    $      13,629        $      13,556 
                                            ------               ------
   
                    LIABILITIES & STOCKHOLDERS  EQUITY

Current Liabilities
- -------------------
     Accounts Payable                $      54,521        $      27,626  
     Accrued Salaries                      164,000              140,000 
     Accrued Interest Payable               19,365               18,000  
     Notes Payable                          49,500               43,400
                                            ------               ------  
     
     Total Current Liabilities             287,386              229,026 
     
Stockholders  Equity
- --------------------
     Common Stock, Authorized:
      100,000,000 Shares
      at $0.001 ParValue:
      19,562,859 Shares
      Issued & Outstanding                  19,562               19,562
 
     Paid In Capital
       (Quasi-Reorganized 
       March 20, 1994 Deficit
       Retained Earnings of
       $2,423,964 Eliminated)              513,847              513,847
 
     Retained Earnings Deficit            (807,166)            (748,879)  
                                          ---------            ---------

     Total Stockholders  Equity           (273,757)            (215,470)
                                          ---------            ---------
TOTAL LIABILITIES & STOCKHOLDERS
 EQUITY                               $     13,629         $     13,556
</TABLE>
The accompanying notes are an integral part of these financial statements

<PAGE>
                           SANGUINE CORPORATION
                       (A Development Stage Company)
                         Statements of Operations
       For the Period January 1, 1996 to December 31, 1996 Unaudited
                   and January 1, 1996 to March 31, 1995
<TABLE>
<CAPTION>
                                               March             March 
                                              31, 1996         31, 1995 
                                              --------         --------
<S>                                      <C>                 <C>
Revenues
- --------
   Interest Income                       $         1         $        1 
                                                   -                  -

          Total Revenues                           1                  1 
Expenses
- --------
   Research & Development                     28,501             21,620 
   Promotion                                     -0-              3,916 
   Salaries                                    4,500              4,500 
   Office Expense                              3,598              2,792 
   Auto Expenses                               1,967                270 
   Legal & Professional Fees                   6,801              2,119 
   Rent                                        3,892              3,986 
   Interest Expense                            1,541              1,365 
   Travel                                        283              1,475 
   Stock Transfer                                -0-                102 
   Consultant Fees                             5,800              2,000 
   Tax & License                               1,175                -0- 
   Depreciation                                  230                230
                                                 ---                --- 

      Total Expenses                          58,288             44,375
                                              ------             ------ 

      Loss for Period                    $   (58,287)        $  (44,374)

      Profit (Loss) Per Share                   (.00)              (.00)

      Weighted Average Shares
      Outstanding                         19,562,859         16,721,859 
</TABLE>

The accompanying notes are an integral part of these financial statements<PAGE>
<PAGE>
                           SANGUINE CORPORATION
                       (A Development Stage Company)
                    Statements of Cash Flows Unaudited
          For the Periods January 1, 1996 to March 31, 1996 and 
                    January 1, 1995 to March 31, 1995  
<TABLE>
<CAPTION>

                                                 March              March  
                                              31, 1995           31, 1995 
                                              --------           --------
<S>                                        <C>              <C>
Cash Flows from Operating Activities
- ------------------------------------
 Net (Loss)                                $   (58,287)     $    (44,374)
 Depreciation                                      230               230 
 Changes in Operating Assets & Liabilities:
  Increase (Decrease)Accounts Payable           26,895            18,462 
  Increase in Interest Payable                   1,365             1,365 
  Increase in Accrued Salaries                  24,000            24,000 
                                                ------            ------

      Net Cash Flows from 
      Operating Activities                      (5,797)             (317)

Cash Flows from Investing Activities               -0-              -0- 
- ------------------------------------

Cash Flows from Financing Activities
- ------------------------------------
 Increase in Notes Payable                       6,100              -0- 
                                                 -----              ---
      Net Cash Flows Provided by
      Financing Activities                       6,100              -0- 
                                                 -----              ---
  
    Increase (Decrease) in Cash                    303             (317)

      Cash at Beginning of Period                  712            1,654 

      Cash at End of Period                $     1,015     $      1,337 
                                                 -----            -----

Disclosure for Cash Flows from:
 
 Interest                                  $    1,541      $      1,365 
 Taxes                                             -0-             -0- 

</TABLE>
The accompanying notes are an integral part of these financial statements
<PAGE>
<PAGE>
                           SANGUINE CORPORATION
                       Notes to Financial Statements

NOTE #1 - Statement Preparation

     The Company has prepared the accompanying financial statements with
interim financial reporting requirements promulgated by the Securities &
Exchange Commission.  The information furnished reflects all adjustments which
are, in the opinion of management, necessary for a fair presentation of
financial position and results of operations. 

     The financial statements should be read in conjunction with the
consolidated financial statements and notes thereto included in the Company s
1995 10-K report. 


<PAGE>
<PAGE>
Item 2.   Management's Discussion and Analysis or Plan of Operation.
- --------------------------------------------------------------------

Plan of Operation.
- ------------------

          The Company has conducted all of its business operations through its
majority owned subsidiary, Sanguine Corporation, a California corporation
("Sanguine California").  Sanguine California is engaged in the development of
a synthetic red blood cell product called "PHER-O2."  The development of this
product presently comprises its sole business operations.  PHER-O2 is composed
of perfluoro-decalin molecules (i.e., synthetic red blood cells), purified
water and a proprietary, synthetic, fluorinated surfactant to hold the
emulsion together.  Perfluoro-decalin has great oxygen-carrying capacity, yet
it can be as much as 900 times smaller than a red blood cell.  Management
believes that PHER-O2 may carry three to four times the oxygen of human blood
per unit volume. This increased oxygen-carrying capacity may make PHER-O2
useful in the treatment of heart attacks, strokes, cancer and other diseases
for which increased oxygenation is beneficial.  Furthermore, the Company
believes that perfluoro-decalin may be effective as an imaging agent in X-ray
imaging, nuclear magnetic resonance (NMR) imaging and CAT scans, without side
effects. Management also believes that PHER-O2 has several other advantages
over human blood:  it can be sterilized to be free of disease; is believed to
have the quality of a universal match for all blood types; can be
mass-produced; and may be stored much longer than human blood.

          Battelle Memorial Institute, through its Battelle Columbus
Operations ("Battelle"), was retained to assist the Company in completing the
emulsion of perfluoro-decalin and the synthetic surfactants that make up
PHER-O2; it is anticipated that on completion of the compounding of PHER-O2,
Battelle will perform initial gross animal tests, which do not require
regulatory approval prior to commencement; however, the data gathered from any
such tests will be subject to regulatory review in the future.  The Company
anticipates that it will manufacture experimental doses of PHER-O2 required to
conduct gross animal testing.

          It is anticipated that continued research and development of PHER-O2
will depend upon the Company's ability to obtain substantial additional equity
or debt funding, as to which no assurance can be given.  See the captions
"Business Development," "Future Capital Requirements; Uncertainty of Future
Funding" and "Patents, Trademarks, Licenses, Franchises, Concessions, Royalty
Agreements or Labor Contracts" of the Company's Annual Report on Form
10-KSB for the fiscal year ended December 31, 1995, which has previously been
filed with the Securities and Exchange Commission.
 
          In its second phase of operations, management intends to continue
developing the perfluorocarbon compounds in PHER-O2 in order to optimize its
quality, and expects to begin animal safety and efficacy trials in accordance
with guidelines of the United States Food and Drug Administration ("FDA") and
comparable foreign regulatory requirements.  

          In the final phase of the Company's proposed business operations, it
intends to complete its United States testing of PHER-O2, receive all
necessary FDA approvals and begin American and Canadian sales for cancer
treatment and angioplasty; and complete overseas testing, begin overseas sales
and begin the construction of manufacturing facilities.  Sanguine California
has previously licensed BioLogix Development Partners, an unaffiliated
California limited partnership, to manufacture and market PHER-O2 in Canada,
including any future Canadian patent rights, and the exclusive right to market
PHER-O2 in U.S. military pre-hospital markets.  In this final phase, the
Company also intends to continue trials to test PHER-O2  for other
applications, including transplant organ preservation and the treatment of
carbon monoxide poisoning, sickle cell anemia, heart attack and stroke.  The
Company will be required to conduct similar rigorous testing and clinical
trials of PHER-O2 for each desired application for which it is sought to be
used.  

          PHER-O2 is still in the research and development stage.  It has not
been tested on animals or humans; nor has any application been submitted to
any federal, state or foreign agency to seek authority for such testing.  This
development process will be time consuming, costly, subject to extreme
governmental regulation and must prove that this product is safe and
efficacious for human use.  Until then, the Company will have no potential for
revenues from operations.  No assurance can be given that the Company will be
able to raise the capital it will need to develop PHER-O2, or that if
sufficient funds are raised, the Company will ever receive requisite federal,
state or foreign agency approval to manufacture or market this product.  See
the captions "Business Development," "Special Risk Factors," "Principal
Products or Services and their Markets," "Competition," "Patents, Trademarks,
Licenses, Franchises, Concessions, Royalty Agreements or Labor Contracts" and
"Governmental Approval of Principal Products or Services" of the Company's
Registration Statement on Form 10-SB-A1, which has previously been filed
with the Securities and Exchange Commission, and which is incorporated herein
by reference. 

Results of Operations.
- ----------------------

          During the quarterly period ending March 31, 1996, the Company's
only business operations were those of Sanguine California.  During this
period, the Company received total revenues of $1 and sustained a net loss of
$58,287.

Liquidity.
- ----------

          During the quarterly period ended March 31, 1996, the Company had
total expenses of $58,288, while receiving $1 in revenues.

                        PART II - OTHER INFORMATION

Item 1.   Legal Proceedings.
- ----------------------------

          None; not applicable.

Item 2.   Changes in Securities.
- --------------------------------

          None; not applicable.

Item 3.   Defaults Upon Senior Securities.
- ------------------------------------------

          None; not applicable.

Item 4.   Submission of Matters to a Vote of Security Holders.
- --------------------------------------------------------------

          None; not applicable.
          
Item 5.   Other Information.
- ----------------------------

          On or about March 11, 1996, the Board of Directors of the Company,
acting without a meeting pursuant to Section 78.315 of the Nevada Revised
Statutes, resolved to appoint David E. Nelson, CPA, Chief Financial Officer of
the Company.  Also on March 11, 1996, Thomas D. Drees, Ph.D., and Anthony G.
Hargreaves, who collectively held in excess of a majority of the issued and
outstanding shares of the Company's common stock, acting without a meeting
pursuant to Section 78.320 of the Nevada Revised Statutes, resolved to elect
Mr. Nelson and Holomon J. Nicholas, II, to the Board of Directors of the
Company, to serve until the next annual meeting of stockholders or until their
respective successors are elected and qualified or their prior resignations or
termination.

Item 6.   Exhibits and Reports on Form 8-K.
- -------------------------------------------

          (a)  Exhibits.

               10-SB-A1 Registration Statement.*

               Form 10-KSB-A1 Annual Report for the 
               Fiscal Year ended December 31, 1994.*

          (b)  Reports on Form 8-K.

               None.

               *  Incorporated herein by reference.







































<PAGE>
 
                               SIGNATURES

          Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this Report to be signed on its behalf by the
undersigned thereunto duly authorized.

                                      SANGUINE CORPORATION



Date: 6/4/96                          By  /s/
     --------------                     -------------------------------------
                                        Thomas C. Drees, CEO and Chairman of   
                                        the Board of Directors


Date: 6/7/96                          By  /s/
     --------------                     -------------------------------------
                                        Holomon J. Nicholas, II
                                        President, COO and Director 
                                  

Date: 6/4/96                          By  /s/
     --------------                     -------------------------------------
                                        Anthony G. Hargreaves
                                        Vice President, Secretary/Treasurer    
                                        and Director


Date: 6/7/96                          By  /s/
     --------------                     -------------------------------------
                                        David E. Nelson, CPA
                                        CFO and Director


Date: 6/4/96                          By  /s/
     --------------                     -------------------------------------
                                        Edward L. Kunkel, Esq.
                                        Director

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<CIK> 0000926287
<NAME> SANGUINE CORPORATION
       
<S>                                        <C>
<PERIOD-TYPE>                              3-MOS
<FISCAL-YEAR-END>                          DEC-31-1996
<PERIOD-END>                               MAR-31-1996
<CASH>                                           1,015
<SECURITIES>                                         0
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                                 1,015
<PP&E>                                           2,614
<DEPRECIATION>                                       0
<TOTAL-ASSETS>                                  13,629
<CURRENT-LIABILITIES>                          287,386
<BONDS>                                              0
                                0
                                          0
<COMMON>                                        19,562
<OTHER-SE>                                   (293,319)
<TOTAL-LIABILITY-AND-EQUITY>                 (273,757)
<SALES>                                              0
<TOTAL-REVENUES>                                     1
<CGS>                                                0
<TOTAL-COSTS>                                        0
<OTHER-EXPENSES>                                56,747
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                               1,541
<INCOME-PRETAX>                               (58,287)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                                  0
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                  (58,287)
<EPS-PRIMARY>                                   (0.00)
<EPS-DILUTED>                                   (0.00)
        

</TABLE>


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