MCKESSON HBOC INC
POS AM, 1999-10-18
DRUGS, PROPRIETARIES & DRUGGISTS' SUNDRIES
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<PAGE>

   As filed with the Securities and Exchange Commission on October 18, 1999
                          Registration No. 333-66359

                          --------------------------

                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549

                        POST-EFFECTIVE AMENDMENT NO. 1
                                      to
                                   FORM S-3
                            REGISTRATION STATEMENT
                                     under
                          the Securities Act of 1933


<TABLE>
<S>                            <C>                                      <C>
    McKESSON HBOC, INC.                   Delaware                          94-3207296
(Exact name of Registrant       (State or other jurisdiction of          (I.R.S.  employer
as specified in its charter)     incorporation or organization)        identification number)
</TABLE>

                                McKesson Plaza
                                One Post Street
                       San Francisco, California  94104
                                (415) 983-8300
  (Address, including zip code, and telephone number, including area code, of
                   Registrant's principal executive offices)

                               Ivan D. Meyerson
        Senior Vice President, General Counsel and Corporate Secretary
                              McKesson HBOC, Inc.
                        McKesson Plaza, One Post Street
                       San Francisco, California  94104
                                (415) 983-8300
          (Name, address, including zip code, and telephone number,
                  including area code, of agent for service)
                             --------------------
                                   Copy to:
                                 Gregg A. Noel
                   Skadden, Arps, Slate, Meagher & Flom LLP
                      300 South Grand Avenue, Suite 3400
                        Los Angeles, California  90071
                                (213) 687-5000

       Approximate date of commencement of proposed sale to the public:
     From time to time after this registration statement becomes effective.

                             --------------------
     If the only securities being registered on this form are being offered
pursuant to dividend or interest reinvestment plans, please check the following
box. [ ]

     If any of the securities being registered on this form are to be offered on
a delayed or continuous basis pursuant to Rule 415 under the Securities Act of
1933, other than securities being offered only in connection with dividend or
interest reinvestment plans, please check the following box. [ ]

     If this form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list the Securities Act registration statement number of the earlier
effective registration statement for the same offering. [ ]

     If this form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering. [ ]

     If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box. [ ]
<PAGE>

                         DEREGISTRATION OF SECURITIES

     The purpose of this Post-Effective Amendment No. 1 to this Registration
Statement is to deregister all shares of common stock, par value $.01 per share
of McKesson HBOC, Inc., a Delaware corporation (previously named McKesson
Corporation) which have not been sold pursuant to this Registration Statement.

     The Securities and Exchange Commission declared this Registration Statement
effective on November 20, 1998.  This Registration Statement was filed in
accordance with a registration rights agreement, dated as of June 22, 1998 (the
"Registration Rights Agreement"), by and among McKesson HBOC, Inc. and the
parties named therein.  In the Registration Rights Agreement, McKesson HBOC,
Inc. agreed to use its reasonable best efforts to keep the Registration
Statement effective for at least 120 days.   This Post-Effective Amendment No. 1
is being filed in accordance with McKesson HBOC, Inc.'s undertaking set forth in
Part II, Item 17(a)(3) of this Registration Statement.

                                    PART II

                    INFORMATION NOT REQUIRED IN PROSPECTUS

Item 16.  List of Exhibits.

<TABLE>
<CAPTION>
Exhibit Number        Description
- - --------------        -----------
<S>                   <C>
24.1*                 Power of Attorney, dated as of May 29, 1998.

24.2**                Power of Attorney, dated as of April 27, 1999.

24.3**                Power of Attorney, dated as of October 12, 1999.
</TABLE>
________

*    Previously filed
**   Filed herewith

                                       2
<PAGE>

                                  SIGNATURES


     Pursuant to the requirements of the Securities Act of 1933, as amended, the
Company certifies that it has reasonable grounds to believe that it meets all of
the requirements for filing on Form S-3 and has duly caused this Post-Effective
Amendment to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of San Francisco, State of California, on the 18th day
of October, 1999.

                              McKesson HBOC, Inc.


                              By:   /s/ Ivan D. Meyerson
                                  ----------------------------------------------
                                  Name:  Ivan D. Meyerson
                                  Title: Senior Vice President, General
                                         Counsel and Corporate Secretary

     Pursuant to the requirements of the Securities Act of 1933, as amended,
this Amendment has been signed below by the following persons in the capacities
and on the date indicated.

<TABLE>
<CAPTION>
            Signature                                 Title
            ---------                                 -----
<S>                                  <C>
               *                                 Co-President and
- - ---------------------------------    Co-Chief Executive Officer and Director
       John H. Hammergren                  (principal executive officer)


               *                                 Co-President and
- - ---------------------------------    Co-Chief Executive Officer and Director
        David L. Mahoney                   (principal executive officer)


               *                     Senior Vice President and Controller and
- - ---------------------------------         Acting Chief Financial Officer
       Heidi E. Yodowitz            (principal financial and accounting officer)


               *
- - ---------------------------------                    Director
      Alfred C. Eckert III


               *
- - ---------------------------------                    Director
       Tully M. Friedman


               *
- - ---------------------------------                    Director
        Alton F. Irby III
</TABLE>


                                       3
<PAGE>

<TABLE>
<CAPTION>
            Signature                                 Title
            ---------                                 -----
<S>                                         <C>

               *
- - ---------------------------------                    Director
       M. Christine Jacobs


               *
- - ---------------------------------                    Director
        Gerald E. Mayo


               *
- - ---------------------------------                    Director
       Charles W. McCall


               *
- - ---------------------------------                    Director
         James V. Napier


               *
- - ---------------------------------                    Director
        David S. Pottruck


               *
- - ---------------------------------                    Director
        Carl E. Reichardt


               *                            Chairman of the Board and
- - ---------------------------------                    Director
        Alan Seelenfreund


               *
- - ---------------------------------                    Director
          Jane E. Shaw


*By:   /s/ Ivan D. Meyerson
    -----------------------------
           Ivan D. Meyerson
           Attorney-in-fact
</TABLE>

Dated: October 18, 1999

                                       4
<PAGE>

                                 EXHIBIT INDEX


Exhibit Number          Description
- - --------------          -----------

24.2                    Power of Attorney, dated as of April 27, 1999

24.3                    Power of Attorney, dated as of October 12, 1999


                                       5

<PAGE>

                                                                    EXHIBIT 24.2


                                POWER OF ATTORNEY

     Each of the undersigned directors and each of the undersigned officers of
McKesson HBOC, Inc., a Delaware corporation (the "Corporation"), does hereby
constitute and appoint Ivan D. Meyerson and Kristina Veaco as his or her true
and lawful attorney-in-fact and agent, each with full power of substitution and
resubstitution (acting alone and without the other), for him or her and in his
or her name, place and stead in any and all capacities, to execute and deliver
in his or her name and on his or her behalf any and all post-effective
amendments to the Registration Statement on Form S-3 (Registration No. 333-
66359) under the Securities Act of 1933, as amended (the "Securities Act"), with
respect to the deregistration of common stock of the Corporation registered
thereunder (the "Common Stock"), and to file the same with all exhibits thereto
and any other documents in connection therewith and any and all other
certificates, letters, reports, statements, applications and any other documents
and instruments in connection with the deregistration of the Common Stock which
such attorney-in-fact and agent deems necessary, advisable or appropriate to
enable the Corporation to comply with (i) the Securities Act, the Securities
Exchange Act of 1934, as amended, and the other federal securities laws of the
United States of America and the rules, regulations and  requirements of the
Securities and Exchange Commission in respect of any thereof; (ii) the
securities or Blue Sky laws of any state or other governmental subdivision of
the United States of America; and (iii) the securities or similar applicable
laws of any foreign jurisdiction, and each of the undersigned hereby grants unto
such attorney-in-fact and agent or his substitute or substitutes, each and every
act and thing requisite and necessary to be done in and about the premises as
fully as to all intents and purposes as he or she might or could do in person,
and does hereby ratify and confirm as his or her own acts and deeds all that
such attorney-in-fact and agent, or his substitute or substitutes, shall
lawfully do or cause to be done by virtue hereof.  Such attorney-in-fact and
agent shall have, and may exercise, all of the powers hereby conferred.

     IN WITNESS WHEREOF, the undersigned has hereunto subscribed this power of
attorney this 27th day of April, 1999.

<TABLE>
<CAPTION>
<S>                                                                  <C>
              /s/ Charles W. McCall                                                /s/ Alfred C. Eckert III
- - -------------------------------------------------                    -------------------------------------------------
                  Charles W. McCall                                                    Alfred C. Eckert III


              /s/ Tully M. Friedman                                                 /s/ James V. Napier
- - -------------------------------------------------                    -------------------------------------------------
                  Tully M. Friedman                                                     James V. Napier


              /s/ Alton F. Irby III                                                 /s/ David S. Pottruck
- - -------------------------------------------------                    -------------------------------------------------
                  Alton F. Irby III                                                     David S. Pottruck


              /s/ M. Christine Jacobs                                               /s/ Carl E. Reichardt
- - -------------------------------------------------                    -------------------------------------------------
                  M. Christine Jacobs                                                   Carl E. Reichardt


              /s/ Gerald E. Mayo
- - -------------------------------------------------
                  Gerald E. Mayo

</TABLE>

                                       1

<PAGE>

                                                                    EXHIBIT 24.3


                                POWER OF ATTORNEY

     Each of the undersigned directors and each of the undersigned officers of
McKesson HBOC, Inc., a Delaware corporation (the "Corporation"), does hereby
constitute and appoint Ivan D. Meyerson and Kristina Veaco as his or her true
and lawful attorney-in-fact and agent, each with full power of substitution and
resubstitution (acting alone and without the other), for him or her and in his
or her name, place and stead in any and all capacities, to execute and deliver
in his or her name and on his or her behalf any and all post-effective
amendments to the Registration Statement on Form S-3 (Registration No. 333-
66359) under the Securities Act of 1933, as amended (the "Securities Act"), with
respect to the deregistration of common stock of the Corporation registered
thereunder (the "Common Stock"), and to file the same with all exhibits thereto
and any other documents in connection therewith and any and all other
certificates, letters, reports, statements, applications and any other documents
and instruments in connection with the deregistration of the Common Stock which
such attorney-in-fact and agent deems necessary, advisable or appropriate to
enable the Corporation to comply with (i) the Securities Act, the Securities
Exchange Act of 1934, as amended, and the other federal securities laws of the
United States of America and the rules, regulations and  requirements of the
Securities and Exchange Commission in respect of any thereof; (ii) the
securities or Blue Sky laws of any state or other governmental subdivision of
the United States of America; and (iii) the securities or similar applicable
laws of any foreign jurisdiction, and each of the undersigned hereby grants unto
such attorney-in-fact and agent or his substitute or substitutes, each and every
act and thing requisite and necessary to be done in and about the premises as
fully as to all intents and purposes as he or she might or could do in person,
and does hereby ratify and confirm as his or her own acts and deeds all that
such attorney-in-fact and agent, or his substitute or substitutes, shall
lawfully do or cause to be done by virtue hereof.  Such attorney-in-fact and
agent shall have, and may exercise, all of the powers hereby conferred.

     IN WITNESS WHEREOF, the undersigned has hereunto subscribed this power of
attorney this 12th day of October, 1999.

<TABLE>
<CAPTION>
<S>                                                                  <C>
              /s/ John H. Hammergren                                                /s/ David L. Mahoney
- - -------------------------------------------------                    -------------------------------------------------
                  John H. Hammergren                                                    David L. Mahoney
</TABLE>

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