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<PAGE> Exhibit 23.1 INDEPENDENT AUDITORS' CONSENT We consent to the incorporation by reference in Registration Statement No. 333-50261 of McKesson HBOC, Inc. on Form S-8 of our report dated September 18, 2000 appearing in the Annual Report on Form 11-K of the McKesson HBOC, Inc. Profit-Sharing Investment Plan for the fiscal year ended March 31, 2000. /s/ Deloitte & Touche LLP San Francisco, California September 26, 2000
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