INKINE PHARMACEUTICAL CO INC
4, 1998-09-10
PHARMACEUTICAL PREPARATIONS
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                                                           OMB APPROVAL        
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- ------                                              OMB Number:  3235-0287
FORM 4                                              Expires: September 30, 1998
- ------                                              Estimated average burden   
                                                    hours per response .... 0.5
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                                 U.S. SECURITIES AND EXCHANGE COMMISSION
                                          WASHINGTON, D.C. 20549
                                       
                               STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
/ / Check this box if no                                                     
    longer subject to         Filed pursuant to Section 16(a) of the Securities 
    Section 16. Form 4            Exchange Act of 1934, Section 17(a) of the 
    or Form 5 obligations         Public Utility Holding Company Act of 1935
    may continue. See              or Section 30(f) of the Investment Company
    Instruction 1(b).                           Act of 1940               

<TABLE> 
<S>                             <C>            <C>                        <C>                <C>          <C>            <C>   
(Print or Type Responses)
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 1. Name and Address of Reporting Person*      2. Issuer Name and Ticker or Trading Symbol   6. Relationship of Reporting Person(s)
 Weisbach, Ph.D.  Jerry                           InKine Pharmaceutical Company, Inc. (INKP)    to Issuer (Check all applicable)
- ---------------------------------------------------------------------------------------------    X  Director         10% Owner
  (Last)          (First)          (Middle)    3. IRS or Social Security  4. Statement for      ----              ---
 InKine Pharmaceutical Company, Inc.              Number of Reporting        Month/Year             Officer (give    Other (Specify
 Sentry Park East                                 Person (Voluntary)                            ----        title ---       below)
 1720 Walton Road                                                            August 1998                    below)
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                 (Street)                                                 5. If Amendment,    7. Individual or Joint/Group Filing 
                                                                             Date of Original    (Check Applicable Line)
                                                                             (Month/Year)      X Form filed by One Reporting Person
                                                                                              --
                                                                                              -- Form filed by More than One Report-
Blue Bell,      Pennsylvania         19422                                                       ing Person
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  (City)           (State)           (Zip)     


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                                               TABLE 1 -- NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
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 1. Title of Security           2. Trans-   3. Transac-  4. Securities Acquired (A)  5.  Amount of Se-    6. Owner-      7. Nature  
  (Instr. 3)                       action      tion         or Disposed of (D)           curities Benefi-    ship           of In-  
                                   Date        Code         (Instr. 3, 4 and 5)          cially Owned at     Form:          direct  
                                               (Instr. 8)                                End of Month        Direct         Benefi-
                                  (Month/                                                (Instr. 3 and 4)    (D) or         cial
                                   Day/   ---------------------------------------                            Indirect       Owner- 
                                   Year)  Code    V      Amount   (A) or    Price                            (I)            ship   
                                                                  (D)                                        (Instr. 4)     (Instr.
                                                                                                                            4)     

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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.                   (Over)
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
                                                                                                                     SEC 1474 (7-96)
 
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<TABLE>
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FORM 4 (CONTINUED)        TABLE II -- DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
                                  (E.G., PUTS, CALLS, WARRANTS, OPTIONS, CONVERTIBLE SECURITIES)

<S>                       <C>          <C>        <C>         <C>              <C>             <C>                   <C>          
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1. Title of Derivative    2. Conver-   3. Trans-  4. Trans-   5. Number of     6. Date Exer-   7. Title and Amount   8. Price     
   Security                  sion or      action     action      Derivative       cisable and     of Underlying         of        
   (Instr. 3)                Exercise     Date       Code        Securities Ac-   Expiration      Securities            Deriv-    
                             Price of     (Month/    (Instr. 8)  quired (A) or    Date            (Instr. 3 and 4)      ative     
                             Deriv-       Day/                   Disposed of (D)  (Month/Day/                           Secur-    
                             ative        Year)                  (Instr. 3, 4     Year)                                 ity       
                             Security                            and 5)                                                 (Instr. 5)
                                                                               -----------------------------------             
                                                                               Date    Expira-            Amount or            
                                                    -------------------------- Exer-   tion       Title   Number of            
                                                    Code  V     (A)     (D)    cisable Date               Shares               
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Stock Option              $1.25          8/3/98        A       20,000          (1)     8/3/08     Common   20,000
(Right to Buy)                                                                                    Stock
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<S>                          <C>                    <C>                         <C>                              
1. Title of Derivative       9. Number of           10. Ownership               11. Nature of                              
   Security                     Derivative              of                          Indirect                     
   (Instr. 3)                   Securities              Derivative                  Beneficial                   
                                Beneficially            Security:                   Ownership                    
                                Owned at End            Direct (D)                  (Instr. 4)                   
                                of Month                or Indirect (I)                                          
                                (Instr. 4)              (Instr. 4)                                               
                                                                                 
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Stock Option
(Right to Buy)                   20,000                 D
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                                137,500(2)
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Explanation of Responses:
 
(1) Option became exercisable as to 4,000 shares on August 3, 1998. It will
    become exercisable with respect to the balance of the shares in annual
    increments of 4,000 shares commencing on August 3, 1999.

(2) Consists of options held prior to the transactions reported hereby.

**  Intentional misstatements or omissions of facts constitute Federal 
    Criminal Violations.                                                         /s/ Jerry Weisbach               September 4, 1998
    See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).                                    -------------------------------  -----------------
                                                                                 **Signature of Reporting Person         Date
                                                                                   Jerry Weisbach, Ph.D.

Note: File three copies of this Form, one of which must be manually signed.                               
      If space provided is insufficient, see Instruction 6 for procedure.                                   

Potential persons who are to respond to the collection of information contained
in this form are not required to respond unless the form displays a currently
valid OMB Number.                                                                                                             Page 2
                                                                                                                     SEC 1474 (7-96)
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