<PAGE>
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(AMENDMENT NO. 1)*
INKINE PHARMACEUTICAL COMPANY, INC.
(Name of Issuer)
COMMON STOCK, $.0001 PAR VALUE
(Title of Class of Securities)
457214 10 4
(CUSIP Number)
DECEMBER 31, 1999
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
/ / Rule 13d-1(b)
/ / Rule 13d-1(c)
/X/ Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class
of securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the Securities
Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of
that section of the Act but shall be subject to all other provisions of
the Act (however, see the Notes).
Page 1 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 2 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Oxford Bioscience Partners II L.P.
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- ------------------------- ----- ------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------- ------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
- ------- ------------------------------------------------------------------------
Page 2 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 3 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Oxford Bioscience Partners (Adjunct) II L.P.
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- ------- ------------------------------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
- ------- ------------------------------------------------------------------------
Page 3 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 4 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Oxford Bioscience Partners (GS-Adjunct) II L.P.
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- ------- ------------------------------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
- ------- ------------------------------------------------------------------------
Page 4 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 5 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
OBP Management II L.P.
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- ------------------------- ----- ------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
- ------- ------------------------------------------------------------------------
Page 5 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 6 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Oxford Bioscience Partners (Bermuda) II Limited Partnership
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Bermuda
- ------------------------- ----- ------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
- ------- ------------------------------------------------------------------------
Page 6 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 7 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
OBP Management (Bermuda) II Limited Partnership
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Bermuda
- ------------------------- ----- ------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
- ------- ------------------------------------------------------------------------
Page 7 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 8 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
OBP Management (Bermuda) II Ltd.
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Bermuda
- ------- ------------------------------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- -----------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
CO
- ------- ------------------------------------------------------------------------
Page 8 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 9 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Edmund M. Olivier
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ------- ------------------------------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
- ------- ------------------------------------------------------------------------
Page 9 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 10 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Cornelius T. Ryan
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ------------------------- ----- ------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
- ------- ------------------------------------------------------------------------
Page 10 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 11 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Alan G. Walton
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ------------------------- ----- ------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
- ------- ------------------------------------------------------------------------
Page 11 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 12 of 19 pages
- ------- ------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Jonathan J. Fleming
- ------- ------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) / /
(b) / /
- ------- ------------------------------------------------------------------------
3 SEC USE ONLY
- ------- ------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ------- ------------------------------------------------------------------------
5 SOLE VOTING POWER
0 Shares
NUMBER OF
----- ------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 2,134,615 Shares
----- ------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 Shares
----- ------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
2,134,615 Shares
- ------------------------- ----- ------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,134,615 Shares
- ------- ------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) / /
- ------- ------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
8.3%
- ------- ------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
- ------- ------------------------------------------------------------------------
Page 12 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 13 of 19 pages
NOTE: This Statement on Schedule 13G is being filed on behalf of: (i) Oxford
Bioscience Partners II L.P., a Delaware limited partnership; (ii) Oxford
Bioscience Partners (Adjunct) II L.P., a Delaware limited partnership; (iii)
Oxford Bioscience Partners (GS-Adjunct) II L.P., a Delaware limited partnership;
(iv) OBP Management II L.P., a Delaware limited partnership; (v) Oxford
Bioscience Partners (Bermuda) II Limited Partnership, a Bermuda limited
partnership; (vi) OBP Management (Bermuda) II Limited Partnership, a Bermuda
limited partnership; (vii) OBP Management (Bermuda) II Ltd., a Bermuda company;
(viii) Edmund M. Olivier; (ix) Cornelius T. Ryan; (x) Alan G. Walton and (xi)
Jonathan J. Fleming.
Item 1(a). NAME OF ISSUER: InKine Pharmaceutical Company, Inc.
Item 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
Sentry Park East, 1720 Walton Road, Blue Bell, Pennsylvania 19422
<TABLE>
<CAPTION>
ITEM 2(a) ITEM 2(b) ITEM 2(c)
Citizenship or Place
Name of Person Filing Address of Organization
--------------------- --------- --------------------
<S> <C> <C>
Oxford Bioscience Partners II L.P. Oxford Bioscience Partners Delaware
("OBP II") 315 Post Road West
Westport, CT 06880
Oxford Bioscience Partners Oxford Bioscience Partners Delaware
(Adjunct) II L.P. ("OBP 315 Post Road West
Adjunct II") Westport, CT 06880
Oxford Bioscience Partners Oxford Bioscience Partners Delaware
(GS-Adjunct) II L.P. ("OBP 315 Post Road West
GS-Adjunct II") Westport, CT 06880
OBP Management II L.P. ("OBP Oxford Bioscience Partners Delaware
Management II") the general 315 Post Road West
partner of OBP II, OBP Adjunct Westport, CT 06880
II and OBP GS-Adjunct II
Oxford Bioscience Partners Richmond House Bermuda
(Bermuda) II Limited Par-la-Ville Road
Partnership ("OBP Bermuda II") Hamilton, Bermuda
OBP Management (Bermuda) II Limited Richmond House Bermuda
Partnership ("OBP Management Par-la-Ville Road
Bermuda II"), the general Hamilton, Bermuda
partner of OBP Bermuda II
</TABLE>
Page 13 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 14 of 19 pages
<TABLE>
<S> <C> <C>
OBP Management (Bermuda) II Ltd. Richmond House Bermuda
("OBP Bermuda II Ltd."), the Par-la-Ville Road
corporate general partner of Hamilton, Bermuda
OBP Management Bermuda II
Edmund M. Olivier, a general Oxford Bioscience Partners United States
partner of OBP Management II 650 Town Center Drive
and OBP Management Bermuda II Costa Mesa, California 92626
Cornelius T. Ryan, a general Oxford Bioscience Partners United States
partner of OBP Management II 315 Post Road West
and OBP Management Bermuda II Westport, CT 06880
Alan G. Walton, a general partner Oxford Bioscience Partners United States
of OBP Management II and OBP 315 Post Road West
Management Bermuda II Westport, CT 06880
Jonathan J. Fleming, a general Oxford Bioscience Partners United States
partner of OBP Management II 31 St. James Avenue, Suite 905
and OBP Management Bermuda II Boston, MA 02116
</TABLE>
Item 2(d). TITLE OF CLASS OF SECURITIES: Common Stock, $.0001 par value.
Item 2(e). CUSIP NUMBER: 457 214 10 4
------------
Item 3. IF THIS STATEMENT IS FILED PURSUANT TO RULES 13d-1(b), OR 13d-2(b) OR
(c), CHECK WHETHER THE PERSON FILING IS A:
(a) / / Broker or Dealer registered under Section 15 of
the Securities Exchange Act of 1934 (the "Act").
(b) / / Bank as defined in Section 3(a)(6) of the Act.
(c) / / Insurance Company as defined in Section 3(a)(19)
of the Act.
(d) / / Investment Company registered under Section 8 of
the Investment Company Act of 1940.
(e) / / An Investment Adviser in accordance with Rule
13d-1(b)(i)(ii)(E) of the Act.
(f) / / Employee Benefit Plan, Pension Fund which is
subject to the provisions of the Employee
Retirement Income Security Act of 1974 or
Endowment Fund; see
Rule 13d-1(b)(1)(ii)(F) of the Act.
(g) / / Parent Holding Company or control person, in
accordance with Rule 13d-1(b)(ii)(G) of the Act.
(h) / / A savings association as defined in Section 3(b)
of the Federal Deposit Insurance Act.
(i) / / A church plan that is excluded from the
definition of investment company under Section
3(c)(14) of the Investment Company Act of 1940.
Page 14 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 15 of 19 pages
(j) / / Group, in accordance with
Rule 13d-1(b)(1)(ii)(J) of the Act.
None of the above.
Item 4. OWNERSHIP.
(a) Amount Beneficially Owned: As of December 31, 1999, each of
the following is the owner of record of the number of shares of
Common Stock set forth next to his, her or its name:
OBP II: 1,220,189 Shares
OBP Adjunct II: 0 Shares
OBP GS-Adjunct II: 0 Shares
OBP Management II: 0 Shares
OBP Bermuda II: 914,426 Shares
OBP Management Bermuda II: 0 Shares
OBP Bermuda II Ltd.: 0 Shares
Mr. Olivier: 0 Shares
Mr. Ryan: 0 Shares
Mr. Walton: 0 Shares
Mr. Fleming: 0 Shares
By virtue of their relationship as affiliated limited
partnerships, whose sole general partners share individual
general partners, OBP II, OBP Adjunct II, OBP GS-Adjunct II and
OBP Bermuda II may be deemed to share voting power and the power
to direct the disposition of the shares of Common Stock which
each partnership owns of record. OBP Management II (as the
general partner of OBP II, OBP Adjunct II and OBP GS-Adjunct II)
and OBP Management Bermuda II (as the general partner of OBP
Bermuda II) may also be deemed to own beneficially the shares of
OBP II, OBP Adjunct II, OBP GS-Adjunct II and OBP Bermuda II.
OBP Bermuda II Ltd., as the corporate general partner of OBP
Management Bermuda II, may also be deemed to own beneficially
the shares of OBP II, OBP Adjunct II, OBP GS-Adjunct II and OBP
Bermuda II. Messrs. Ryan, Walton, Olivier and Fleming are
general partners of both OBP Management II, the general partner
of OBP II, OBP Adjunct II, and OBP GS-Adjunct II, and OBP
Management Bermuda II, the general partner of OBP Bermuda II.
Therefore, each of Messrs. Ryan, Walton, Olivier and Fleming,
the general partners of OBP Management II and OBP Management
Bermuda II, may be deemed to own beneficially the shares held by
OBP II and OBP Bermuda II.
(b) Percent of Class:
OBP II: 8.3%
OBP Adjunct II: 8.3%
OBP GS-Adjunct II: 8.3%
OBP Management II: 8.3%
OBP Bermuda II: 8.3%
OBP Management Bermuda II: 8.3%
OBP Bermuda II Ltd.: 8.3%
Mr. Olivier: 8.3%
Mr. Ryan: 8.3%
Mr. Walton: 8.3%
Mr. Fleming: 8.3%
The foregoing percentages are calculated based on the 25,730,294
shares of Common Stock reported to be outstanding as of November
12, 1999 in the Quarterly Report on Form 10-Q of InKine
Pharmaceutical Company, Inc. for the quarter ended September 30,
1999, as adjusted pursuant to Rule 13d-3 (d)(1) of the Act.
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
Page 15 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 16 of 19 pages
OBP II: 0 Shares
OBP Adjunct II: 0 Shares
OBP GS-Adjunct II: 0 Shares
OBP Management II: 0 Shares
OBP Bermuda II: 0 Shares
OBP Management Bermuda II: 0 Shares
OBP Bermuda II Ltd.: 0 Shares
Mr. Olivier: 0 Shares
Mr. Ryan: 0 Shares
Mr. Walton: 0 Shares
Mr. Fleming: 0 Shares
(ii) shared power to vote or to direct the vote:
OBP II: 2,134,615 Shares
OBP Adjunct II: 2,134,615 Shares
OBP GS-Adjunct II: 2,134,615 Shares
OBP Management II: 2,134,615 Shares
OBP Bermuda II: 2,134,615 Shares
OBP Management Bermuda II: 2,134,615 Shares
OBP Bermuda II Ltd.: 2,134,615 Shares
Mr. Olivier: 2,134,615 Shares
Mr. Ryan: 2,134,615 Shares
Mr. Walton: 2,134,615 Shares
Mr. Fleming: 2,134,615 Shares
(iii) sole power to dispose or to direct the disposition of:
OBP II: 0 Shares
OBP Adjunct II: 0 Shares
OBP GS-Adjunct II: 0 Shares
OBP Management II: 0 Shares
OBP Bermuda II: 0 Shares
OBP Management Bermuda II: 0 Shares
OBP Bermuda II Ltd.: 0 Shares
Mr. Olivier: 0 Shares
Mr. Ryan: 0 Shares
Mr. Walton: 0 Shares
Mr. Fleming: 0 Shares
(iv) shared power to dispose or to direct the disposition of:
OBP II: 2,134,615 Shares
OBP Adjunct II: 2,134,615 Shares
OBP GS-Adjunct II: 2,134,615 Shares
OBP Management II: 2,134,615 Shares
OBP Bermuda II: 2,134,615 Shares
OBP Management Bermuda II: 2,134,615 Shares
OBP Bermuda II Ltd.: 2,134,615 Shares
Mr. Olivier: 2,134,615 Shares
Mr. Ryan: 2,134,615 Shares
Mr. Walton: 2,134,615 Shares
Mr. Fleming: 2,134,615 Shares
Page 16 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 17 of 19 pages
Each of OBP II, OBP Adjunct II, OBP GS-Adjunct II, OBP Management
II, OBP Bermuda II, OBP Management Bermuda II, OBP Bermuda II
Ltd., Mr. Olivier, Mr. Ryan, Mr. Walton and Mr. Fleming expressly
disclaims beneficial ownership of any shares of Common Stock of
InKine Pharmaceutical Company, Inc., except any shares held
directly of record.
Item 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
If this statement is being filed to report the fact that as of
the date hereof the reporting person has ceased to be the
beneficial owner of more than five percent of the class of
securities, check the following: |_|
Item 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.
Not applicable.
Item 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING
COMPANY.
Not applicable.
Item 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
Not applicable. OBP II, OBP Adjunct II, OBP GS-Adjunct II, OBP
Bermuda II, OBP Management Bermuda II, OBP Bermuda II Ltd., Mr.
Olivier, Mr. Ryan, Mr. Walton and Mr. Fleming expressly disclaim
membership in a "group" as defined in Rule 13d-1(b)(ii)(J) of the
Act.
Item 9. NOTICE OF DISSOLUTION OF GROUP.
Not applicable.
Item 10. CERTIFICATION.
Not applicable. This statement on Schedule 13G is not filed
pursuant to Rule 13d-1(b) or Rule 13d-1(c).
Page 17 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 18 of 19 pages
SIGNATURE
After reasonable inquiry and to the best of his, her or its knowledge
and belief, each of the undersigned certifies that the information set forth in
this statement is true, complete and correct. We also hereby agree to file this
statement jointly pursuant to the agreement set forth as EXHIBIT 1 to our
initial Schedule 13G filing.
Dated: February 3, 2000
OXFORD BIOSCIENCE PARTNERS II L.P.
By: OBP Management II L.P., its general partner
By: /S/ JONATHAN J. FLEMING
---------------------------------
Jonathan J. Fleming
General Partner
OXFORD BIOSCIENCE PARTNERS (ADJUNCT) II L.P.
By: OBP Management II L.P., its general partner
By: /S/ JONATHAN J. FLEMING
---------------------------------
Jonathan J. Fleming
General Partner
OXFORD BIOSCIENCE PARTNERS
(GS - ADJUNCT) II L.P.
By: OBP Management II L.P., its general partner
By: /S/ JONATHAN J. FLEMING
---------------------------------
Jonathan J. Fleming
General Partner
OBP MANAGEMENT II L.P.
By: /S/ JONATHAN J. FLEMING
---------------------------------
Jonathan J. Fleming
General Partner
OXFORD BIOSCIENCE PARTNERS (BERMUDA) II LIMITED PARTNERSHIP
By: OBP Management (Bermuda) II Limited Partnership, its
general partner
By: /S/ JONATHAN J. FLEMING
---------------------------------
Jonathan J. Fleming
General Partner
Page 18 of 19 pages
<PAGE>
CUSIP No. 457214 10 4 13G Page 19 of 19 pages
OBP MANAGEMENT (BERMUDA) II LIMITED PARTNERSHIP
By: OBP Management (Bermuda) II Ltd., its general partner
By: /S/ JONATHAN J. FLEMING
---------------------------------
Jonathan J. Fleming
Director
OBP MANAGEMENT (BERMUDA) II LTD.
By: /S/ JONATHAN J. FLEMING
---------------------------------
Jonathan J. Fleming
Director
/S/ CORNELIUS T. RYAN
---------------------------------
Cornelius T. Ryan
/S/ ALAN G. WALTON
---------------------------------
Alan G. Walton
/S/ EDMUND M. OLIVIER
---------------------------------
Edmund M. Olivier
/S/ JONATHAN J. FLEMING
---------------------------------
Jonathan J. Fleming
Page 19 of 19 pages
ROSEN6178/6.924797-1
