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: FORM 3 : : OMB APPROVAL :
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:OMB NUMBER 3235-0104:
:EXPIRES: September 30, 1998:
:ESTIMATED AVERAGE BURDEN :
:HOURS PER RESPONSE.... 0.5 :
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U.S. SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES
Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
Section 17(a) of the Public Utility Holding Company Act of 1935 or
Section 30(f) of the Investment Company Act of 1940
(Print or Type Responses)
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1. Name and Address of Reporting Person*
SkyePharma plc
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(Last) (First) (Middle)
105 Piccadilly
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(Street)
London W1V 9FN, England
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(City) (State) (Zip)
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2. Date of Event Requiring Statement (Month/Day/Year)
10/19/98
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3. IRS or Social Security Number of Reporting Person (Voluntary)
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4. Issuer Name AND Ticker or Trading Symbol
DepoTech Corporation, DEPO
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5. Relationship of Reporting Person(s) to Issuer (Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (Specify below)
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6. If Amendment, Date of Original (Month/Day/Year)
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7. Individual or Joint/Group Filing (Check Applicable Line)
__X__ Form filed by One Reporting Person
_____ Form filed by More than One Reporting Person
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<PAGE>
TABLE I-NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
<TABLE>
<CAPTION>
1. Title of Security 2. Amount of Securities 3. Ownership Form: Direct (D) 4. Nature of Indirect
(Instr. 4) Benefically Owned or Indirect (I) (Instr. 5) Beneficial Ownership
(Instr. 4) (Instr. 5)
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<S> <C> <C> <C>
Common Stock of no par value 2,857,143 D
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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. (Over)
<FN>
* If the form is filed by more than one reporting person, see Instruction 5(b)(v). SEC 1473 (7-96)
</FN>
</TABLE>
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FORM 3 (CONTINUED)
TABLE II -- DERIVATIVE SECURITIES BENEFICIALLY OWNED (E.G., PUTS, CALLS,
WARRANTS, OPTIONS, CONVERTIBLE SECURITIES)
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1. Title of Derivative Security (Instr. 4)
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2. Date Exercisable and Expiration Date (Month/Day/Year)
Date Exercisable Expiration Date
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3. Title and Amount of Underlying Derivative Security (Instr. 4)
Title Amount or Number of Shares
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4. Conversion or Exercise Price of Derivative Security
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5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
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6. Nature of Indirect Beneficial Ownership (Instr. 5)
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Explanation of Responses:
** Intentional misstatements or omissions of facts constitute Federal Criminal
Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed.
If space is insufficient, See Instruction 6 for procedure.
/s/ Peter Warburton 10/29/98
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**Signature of Reporting Person Date
Peter Warburton
Company Secretary and
International Counsel,
SkyePharma plc
Potential persons who are to respond to the
collection of information contained in this
form are not required to respond unless the Page 2
form displays a currently valid OMB Number. SEC 1474 (7-96)
