HANCOCK JOHN INSTITUTIONAL SERIES TRUST
497, 1996-04-09
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                     JOHN HANCOCK INSTITUTIONAL SERIES TRUST

                 - John Hancock Small Capitalization Equity Fund
                     - John Hancock Dividend Performers Fund
                         - John Hancock Active Bond Fund
                         - John Hancock Global Bond Fund
                     - John Hancock Multi-Sector Growth Fund
                    - John Hancock International Equity Fund
                Supplement to Prospectus dated December 11, 1995

The paragraphs under the following  headings in the "Organization and Management
of the  Funds"  section on pages 22 and 23 of the  prospectus  are  replaced  as
follows:

Small Capitalization Fund
As of  April  1996  Bernice  S.  Behar  has  become  primarily  responsible  for
management of the Fund  assisted by a group of portfolio  managers and analysts.
Ms. Behar, a Senior Vice  President,  has been associated with the Adviser since
1991.

Dividend Performers Fund
John F. Snyder III has been primarily  responsible  for management of the equity
securities of the Fund since its inception.  As of April 1996 Barry H. Evans has
become  primarily  responsible for management of the fixed income  securities of
the Fund.  They are assisted by Jere Estes and Thomas  Weary.  Mr.  Snyder is an
Executive Vice President of the Adviser and has been associated with the Adviser
since 1991.  Mr. Evans is a Senior Vice President of the Adviser and has managed
bond funds since he joined the Adviser in 1986.

Active Bond Fund
James K. Ho has been primarily  responsible for the management of the Fund since
its inception. Mr. Ho is assisted by a group of portfolio managers and analysts.
Mr. Ho, an Executive Vice President,  has been associated with the Adviser since
1985.

Global Bond Fund
Lawrence J. Daly and Anthony A. Goodchild have been  primarily  responsible  for
management of the Fund since its  inception.  As of April 1996 Janet L. Clay has
joined Messrs. Daly and Goodchild as a co-portfolio manager of the Fund. Messrs.
Daly and Goodchild, Senior Vice Presidents, joined the Adviser 1994 and prior to
that were Senior Vice Presidents at Putnam Investments.  Ms. Clay, a Second Vice
President,  joined the Adviser in 1995 and prior to that was an  Assistant  Vice
President at Putnam  Investments.  Ms. Clay has also served in various  research
positions at Colonial Management Associates.

Multi-Sector Growth Fund
As of April  1996  Kevin R.  Baker  has  become  primarily  responsible  for the
management of the Fund  assisted by a group of portfolio  managers and analysts.
Mr. Baker, a Second Vice  President,  was President of Baker Capital  Management
from 1991 until joining the Adviser in 1994.

International Equity Fund
David S. Beckwith and John L. F. Wills have been primarily  responsible  for the
management of the Fund since its  inception.  Mr.  Beckwith,  a Vice  President,
joined the Adviser in 1992 and prior to that was associated with Freedom Capital
Management,  an affiliate of the Adviser. Mr. Wills is managing director of JHAI
and has been associated with the Adviser since 1987.


April 10, 1996



KB00S-4-96



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