HANCOCK JOHN INSTITUTIONAL SERIES TRUST
497, 1997-11-19
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                     JOHN HANCOCK INSTITUTIONAL SERIES TRUST

                  Supplements to Prospectus dated July 1, 1997


                      John Hancock Dividend Performers Fund

The Dividend  Performers  Fund's (the "Fund") strategy seeks to invest in common
stocks  with a  record  of  having  increased  their  dividends  in  each of the
preceding ten or more years.  Therefore,  The Fund's investment policy regarding
fixed income and below  investment  grade  securities is being  eliminated.  The
Fund's  strategy as well as its team leader,  John F. Snyder,  III, have been in
place since the Fund's inception.

In order to accomplish this change the Prospectus should be modified as follows:

Delete the second paragraph on page 12 and replace with the following:

Under normal circumstances, the Fund invests at least 65% of its total assets in
dividend  paying  securities.  The  Adviser  expects  that  common  stocks  will
ordinarily  offer the greatest  dividend paying  potential and will constitute a
majority of the Fund's assets.  For defensive  purposes,  however,  the Fund may
temporarily  hold high grade  short-term  debt  securities.  The Adviser and the
Fund's  subadviser,  Sovereign Asset Management Corp.  ("SAMCorp"),  will select
securities for the Fund's portfolio mainly for thier investment  character based
upon  generally  accepted  elements  of  intrinsic  value,   including  industry
position,  management,  financial  strength,  earnings power,  marketability and
prospects for future growth.

Delete the fourth paragraph on page 12 of the Prospectus.

The paragraph under the following heading in the "Organization and Management of
the Funds" section on page 23 of the prospectus is replaced as follows:

Dividend Performers Fund

John F. Snyder, III, assisted by a group of portfolio managers and analysts, has
been primarily  responsible for management of the Fund since its inception.  Mr.
Snyder is an executive vice president of the Adviser, has been in the investment
business since 1972 and has been associated with the Adviser since 1991.

Delete all references to Dividend Performers Fund under the heading "Lower Rated
Securities" on page 30 of the Prospectus.

November 17, 1997


                          John Hancock Global Bond Fund

Replace the second sentence of the fourth  paragraph on page 9 of the Prospectus
with the following:

The Fund may, however,  invest less than 35% of its total assets in fixed-income
debt securities rated, at the time of investment, as low as CCC by S&P or Caa by
Moody's  or their  respective  equivalent  ratings  and  unrated  securities  of
comparable credit quality.


September 10, 1997



KB0PS  11/97

<PAGE>

                     JOHN HANCOCK INSTITUTIONAL SERIES TRUST
               Supplements to Statement of Additional Information
                               dated July 1, 1997



                      John Hancock Dividend Performers Fund


Replace the first sentence of the second  paragraph under  "Dividend  Performers
Fund" on page 5 of the Statement of Additional Information with the following:

The Fund may invest 100% of its total assets in common  stocks or, for defensive
purposes, may temporarily hold cash or high grade short-term debt securities.


Delete the last sentence of the last paragraph under "Dividend  Performers Fund"
on page 5 of the Statement of Additional Information.

Delete all references to Dividend Performers Fund under the heading "Lower Rated
High  Yield  Debt  Obligations"  on  page  23 of  the  Statement  of  Additional
Information.



November 17, 1997




                          John Hancock Global Bond Fund



Replace the fourth  sentence of the first  paragraph on page 23 of the Statement
of Additional  Information with the following:  Global Bond Fund may invest less
than 35% of its total assets in securities rated as low as CCC by S&P or Caa by
Moody's and their equivalents.

September 10, 1997














K0SAIS  11/97



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