HANCOCK JOHN INSTITUTIONAL SERIES TRUST
497, 1997-06-13
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                     JOHN HANCOCK INSTITUTIONAL SERIES TRUST


                     -John Hancock Multi-Sector Growth Fund

                 Supplement to Prospectus dated December 2, 1996


The discussion of who is responsible  for the day-to-day  management of the Fund
contained in the  "Organization  and Management of the Fund" section is replaced
with the following:

Robert  G.  Freedman,  Benjamin  A.  Hock,  Jr.,  CFA and James M. Boyd lead the
portfolio  management team. Mr. Freedman,  is Vice Chairman and Chief Investment
Officer of John Hancock Advisers, Inc. (the "Adviser"). He joined the Adviser in
1984 and has been in the investment business since 1968. Mr. Hock, a Senior Vice
President,  joined the Adviser in 1994 and has been in the  investment  business
since 1974. Mr. Boyd, an assistant portfolio manager, has been with John Hancock
Funds since 1992.

June 10, 1997

KB00S 6/97



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